PBB geneid 28977 28Sribosomal protein L42, mitochondrial is a protein that in humans is encoded by the MRPL42 gene . ref name pmid11279123 cite journal author Cavdar Koc E, Burkhart W, Blackburn K, Moseley A, Spremulli LL title The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present journal J Biol Chem volume 276 issue 22 pages 19363 74 year 2001 month May pmid 11279123 pmc doi 10.1074 jbc.M100727200 ref ref name pmid11042152 cite journal author Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z title Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34 hematopoietic stem progenitor cells journal Genome Res volume 10 issue 10 pages 1546 60 year 2000 month Nov pmid 11042152 pmc 310934 doi 10.1101 gr.140200 ref ref name entrez cite web title Entrez Gene MRPL42 mitochondrial ribosomal protein L42 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 28977 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes mitoribosomes consist of a small 28S ... to both the 28S and the 39S subunits. Further experiments will be needed to identify the specific ..., and 15q. ref name entrez cite web title Entrez Gene MRPL42 mitochondrial ribosomal protein L42 url ... cite journal author Kenmochi N, Suzuki T, Uechi T, et al. title The human mitochondrial ribosomal ... ribosome. Analysis of the complement of ribosomal proteins present. journal J. Biol. Chem. volume ... author Zhang Z, Gerstein M title Identification and characterization of over 100 mitochondrial ribosomal ... more details
Infobox rfam Name Ornate Large Extremophilic RNA image OLE secondary structure.jpg width caption Predicted secondary structure and sequence conservation of OLE Symbol OLE AltSymbols Rfam RF01071 miRBase miRBase family RNA type Gene Tax domain Bacteria GO SO SO 0001263 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData OLE RNA Ornate Large Extremophilic RNA is a conserved RNA structure present in certain bacteria . ref cite journal author Puerta Fernandez E, Barrick JE, Roth A, Breaker RR title Identification of a large noncoding RNA in extremophilic eubacteria journal Proc. Natl. Acad. Sci. U.S.A. volume 103 issue 51 pages 19490 5 year 2006 month December pmid 17164334 pmc 1748253 doi 10.1073 pnas.0607493103 url ref The RNA averages roughly 610 nucleotides in length. The only known RNAs that are longer than OLE RNA are ribozyme s such as the group II intron and ribosomalRNA s. The exceptional length and highly conserved structure of OLE RNA prompted the hypothesis that OLE RNA could be a ribozyme, or otherwise perform an intricate biochemical task. OLE RNAs are predominantly found in the order Clostridiales , but other kinds of Firmicute s contain OLE RNAs as well. Organisms containing OLE RNA are predominantly extremophile s and anaerobe s. OLE RNAs are transcribed as RNA, and experiments in Bacillus halodurans show that it is transcribed in a mRNA with 10 other gene s. The adjacent genes are conserved in the vicinity of OLE RNA in most species containing it, but in Desulfitobacterium hafniense they are located elsewhere on the chromosome . OLE RNAs are processed from the larger transcript into a shorter RNA that roughly corresponds to the conserved ... in species with the presence of OLE RNA. This correlation suggests a possible functional association between the RNA and the protein. References references External links Rfam id RF01071 name OLE RNA Category Non coding RNA molecular cell biology stub ... more details
A ribosomal binding site RBS is a sequence on mRNA that is bound by the ribosome when initiating translation biology protein translation . It can be either the 5 cap of a messenger RNA in eukaryotes , a region 6 7 nucleotides upstream of the start codon AUG in prokaryotes called the Shine Dalgarno sequence , or an internal ribosome entry site IRES in viruses. The sequence is complementary to the 3 end of the rRNA. The ribosome searches for this site and binds to it through base pairing of nucleotides. Then, the ribosome begins the translation process and recruits initiation factors. After finding the ribosome binding site in eukaryotes, the ribosome recognizes the Kozak consensus sequence and begins translation at the 1 AUG codon. See also Alpha operon ribosome binding site GeneticTranslation Category Protein biosynthesis Category Molecular biology Category Drug interaction Category Cell biology genetics stub ... more details
Infobox rfam Name Small nucleolar RNA SNORD73 image RF00071.jpg width caption Predicted secondary structure and sequence conservation of SNORD73 Symbol SNORD73 AltSymbols U73 Rfam RF00071 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA CD box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000593 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData snoRNA U73 also known as SNORD73 is a non coding RNA ncRNA molecule which functions in the biogenesis modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA. snoRNA U73 is a member of the SnoRNA C.2FD box C D box class of snoRNAs which contain the conserved sequence motifs known as the C box UGAUGA and the D box CUGA . Most of the members of the box C D family ... box C D snoRNPs are able to reproduce site specific 2 O ribose methylation of target RNA in vitro journal ... issue 19 pmc 134041 ref U73 is encoded within the intron s of ribosomal proteins ribosomal protein S3a and contains a 12 nucleotide region of complementarity to a conserved sequence in 28SribosomalRNA rRNA . ref cite journal last Rebane first A coauthors Tamme R, Laan M, Pata I, Metspalu A year 1998 title A novel snoRNA U73 is encoded within the introns of the human and mouse ribosomal protein ... 5 issue 2 ref U73 has been demonstrated to function as a 2 O ribose methylation small nucleolar RNA guide RNA for pre 28S rRNA. ref cite journal last Rebane first A coauthors Roomere H, Metspalu A. year 2002 title Locations of several novel 2 O methylated nucleotides in human 28S rRNA journal BMC Mol ... External links Rfam id RF00071 name Small nucleolar RNA SNORD73 http www snorna.biotoul.fr plus.php ... for SNORD73B Small nucleolar RNA Category Small nuclear RNA molecular cell biology stub ... more details
PBB geneid 64975 39S ribosomal protein L41, mitochondrial is a protein that in humans is encoded by the MRPL41 gene . ref name pmid11543634 cite journal author Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T title The human mitochondrial ribosomal protein genes mapping of 54 genes to the chromosomes and implications for human disorders journal Genomics volume 77 issue 1 2 pages 65 70 year 2001 month Sep pmid 11543634 pmc doi 10.1006 geno.2001.6622 ref ref name entrez cite web title Entrez Gene MRPL41 mitochondrial ribosomal protein L41 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 64975 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Mammalian mitochondrial ribosomal protein s are encoded by nuclear genes and help in protein synthesis within the mitochondrion . Mitochondrial ribosomes mitoribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical ... subunit protein that belongs to the YmL27 ribosomal protein family. ref name entrez References reflist ... S, Kitakawa M, Herfurth E, et al. title Mammalian mitochondrial ribosomal proteins. N terminal amino ... mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. journal J. Biol ... ribosomal protein pseudogenes in the human genome. journal Genomics volume 81 issue 5 pages 468 ... cite journal author Yoo YA, Kim MJ, Park JK, et al. title Mitochondrial ribosomal protein L41 suppresses ... author Kim MJ, Yoo YA, Kim HJ, et al. title Mitochondrial ribosomal protein L41 mediates serum starvation ... more details
PBB geneid 6171 60S ribosomal protein L41 is a protein that in humans is encoded by the RPL41 gene . ref name pmid1326959 cite journal author Klaudiny J, von der Kammer H, Scheit KH title Characterization by cDNA cloning of the mRNA of a highly basic human protein homologous to the yeast ribosomal protein YL41 journal Biochem Biophys Res Commun volume 187 issue 2 pages 901 6 year 1992 month Oct pmid 1326959 pmc doi 10.1016 0006 291X 92 91282 U ref ref name pmid9582194 cite journal author Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 issue 5 pages 509 23 year 1998 month Aug pmid 9582194 pmc doi 10.1101 gr.8.5.509 ref ref name entrez cite web title Entrez Gene RPL41 ribosomal protein L41 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6171 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with the yeast ribosomal protein YL41, belongs to the L41E family of ribosomal proteins. It is located ... variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal ... author Wool IG, Chan YL, Gl ck A title Structure and evolution of mammalian ribosomal proteins ... 94 90433 2 cite journal author Lee JH, Kim JM, Kim MS, et al. title The highly basic ribosomal protein ... S title Genomic structure of the human ribosomal protein L41 gene. journal Biochem. Mol. Biol. Int ... N title A complete map of the human ribosomal protein genes assignment of 80 genes to the cytogenetic ... more details
Infobox rfam Name Small nucleolar RNA SNORA43 image RF00416.jpg width caption Predicted secondary structure and sequence conservation of SNORA43 Symbol SNORA43 AltSymbols snoACA43 Rfam RF00416 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData Small nucleolar RNA SNORA43 also known as ACA43 is a non coding RNA ncRNA molecule which functions in the biogenesis modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA . ACA43 was originally cloned from HeLa cells ref name pmid15199136 cite journal author Kiss AM, Jady BE, Bertrand E, Kiss T title Human box H ACA pseudouridylation guide RNA machinery journal Mol. Cell. Biol. volume 24 issue 13 pages 5797 807 year 2004 pmid 15199136 doi 10.1128 MCB.24.13.5797 5807.2004 pmc 480876 ref and belongs to the SnoRNA H.2FACA box H ACA box class of snoRNAs as it has the predicted hairpin hinge hairpin tail structure, has the conserved H ACA box motifs and is found associated with Nucleolar protein, member A1 GAR1 protein . snoRNA ACA43 is predicted to guide the pseudouridylation of U4938 of 28SribosomalRNA rRNA . Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine . References reflist 1 External links Rfam id RF00416 name Small nucleolar RNA SNORA43 http www snorna.biotoul.fr plus.php?id ACA43 snoRNAbase entry for ACA43 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA SNORA ... more details
Infobox rfam Name Small nucleolar RNA SNORA52 image RF00419.jpg width caption Predicted secondary structure and sequence conservation of SNORA52 Symbol SNORA52 AltSymbols snoACA52 Rfam RF00419 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData Small nucleolar RNA SNORA52 also known as ACA52 is a non coding RNA ncRNA molecule which functions in the biogenesis modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA . ACA52 was originally cloned from HeLa cells ref name pmid15199136 cite journal author Kiss AM, Jady BE, Bertrand E, Kiss T title Human box H ACA pseudouridylation guide RNA machinery journal Mol. Cell. Biol. volume 24 issue 13 pages 5797 807 year 2004 pmid 15199136 doi 10.1128 MCB.24.13.5797 5807.2004 pmc 480876 ref and belongs to the SnoRNA H.2FACA box H ACA box class of snoRNAs as it has the predicted hairpin hinge hairpin tail structure, has the conserved H ACA box motifs and is found associated with GAR1 protein. snoRNA ACA52 is predicted to guide the pseudouridylation of U3823 of 28SribosomalRNA rRNA . Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine . References reflist 1 External links Rfam id RF00419 name Small nucleolar RNA SNORA52 http www snorna.biotoul.fr plus.php?id ACA52 snoRNAbase entry for ACA52 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA SNORA ... more details
Infobox rfam Name Small nucleolar RNA SNORA54 image RF00430.jpg width caption Predicted secondary structure and sequence conservation of SNORA54 Symbol SNORA54 AltSymbols snoACA54 Rfam RF00430 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData Small nucleolar RNA SNORA54 also known as ACA54 is a non coding RNA ncRNA molecule which functions in the biogenesis modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA . ACA54 was originally cloned from HeLa cells ref name pmid15199136 cite journal author Kiss AM, Jady BE, Bertrand E, Kiss T title Human box H ACA pseudouridylation guide RNA machinery journal Mol. Cell. Biol. volume 24 issue 13 pages 5797 807 year 2004 pmid 15199136 doi 10.1128 MCB.24.13.5797 5807.2004 pmc 480876 ref and belongs to the SnoRNA H.2FACA box H ACA box class of snoRNAs as it has the predicted hairpin hinge hairpin tail structure, has the conserved H ACA box motifs and is found associated with GAR1 protein. snoRNA ACA54 is predicted to guide the pseudouridylation of U3801 of 28SribosomalRNA rRNA . Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine . References reflist 1 External links Rfam id RF00430 name Small nucleolar RNA SNORA54 http www snorna.biotoul.fr plus.php?id ACA54 snoRNAbase entry for ACA54 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA SNORA ... more details
Infobox rfam Name Small nucleolar RNA SNORA56 image RF00417.jpg width caption Predicted secondary structure and sequence conservation of SNORA56 Symbol SNORA56 AltSymbols snoACA56 Rfam RF00417 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData Small nucleolar RNA SNORA56 also known as ACA56 is a non coding RNA ncRNA molecule which functions in the biogenesis modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA . ACA56 was originally cloned from HeLa cells ref name pmid15199136 cite journal author Kiss AM, Jady BE, Bertrand E, Kiss T title Human box H ACA pseudouridylation guide RNA machinery journal Mol. Cell. Biol. volume 24 issue 13 pages 5797 807 year 2004 pmid 15199136 doi 10.1128 MCB.24.13.5797 5807.2004 pmc 480876 ref and belongs to the SnoRNA H.2FACA box H ACA box class of snoRNAs as it has the predicted hairpin hinge hairpin tail structure, has the conserved H ACA box motifs and is found associated with GAR1 protein. snoRNA ACA56 is predicted to guide the pseudouridylation of U1664 of 28SribosomalRNA rRNA . Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine . References reflist 1 External links Rfam id RF00417 name Small nucleolar RNA SNORA56 http www snorna.biotoul.fr plus.php?id ACA56 snoRNAbase entry for ACA56 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA SNORA ... more details
Infobox rfam Name Small nucleolar RNA SNORA61 image RF00420.jpg width caption Predicted secondary structure and sequence conservation of SNORA61 Symbol SNORA61 AltSymbols snoACA61 Rfam RF00420 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData Small nucleolar RNA SNORA61 also known as ACA61 is a non coding RNA ncRNA molecule which functions in the biogenesis modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA . ACA61 was originally cloned from HeLa cells ref name pmid15199136 cite journal author Kiss AM, Jady BE, Bertrand E, Kiss T title Human box H ACA pseudouridylation guide RNA machinery journal Mol. Cell. Biol. volume 24 issue 13 pages 5797 807 year 2004 pmid 15199136 doi 10.1128 MCB.24.13.5797 5807.2004 pmc 480876 ref and belongs to the SnoRNA H.2FACA box H ACA box class of snoRNAs as it has the predicted hairpin hinge hairpin tail structure, has the conserved H ACA box motifs and is found associated with GAR1 protein. snoRNA ACA61 is predicted to guide the pseudouridylation of U2495 of 28SribosomalRNA rRNA . Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine . References reflist 1 External links Rfam id RF00420 name Small nucleolar RNA SNORA61 http www snorna.biotoul.fr plus.php?id ACA61 snoRNAbase entry for ACA61 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA SNORA ... more details
Infobox rfam Name Small nucleolar RNA SNORA68 image RF00263.jpg width caption Predicted secondary structure and sequence conservation of SNORA68 Symbol SNORA68 AltSymbols U68 Rfam RF00263 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData Small nucleolar RNA SNORA68 also known as U68 is a non coding RNA ncRNA molecule which functions in the biogenesis modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA . ACA68 was originally cloned from HeLa cells ref name pmid9106664 cite journal author Ganot P, Caizergues Ferrer M, Kiss T title The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation journal Genes Dev. volume 11 issue 7 pages 941 56 year 1997 pmid 9106664 doi 10.1101 gad.11.7.941 ref and belongs to the SnoRNA H.2FACA box H ACA box class of snoRNAs as it has the predicted hairpin hinge hairpin tail structure, has the conserved H ACA box motifs and is found associated with GAR1 protein. snoRNA ACA68 is predicted to guide the pseudouridylation of U4393 of 28SribosomalRNA rRNA . Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine . References reflist 1 External links Rfam id RF00263 name Small nucleolar RNA SNORA68 http www snorna.biotoul.fr plus.php?id U68 snoRNAbase entry for U68 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA SNORA ... more details
PBB geneid 11224 60S ribosomal protein L35 is a protein that in humans is encoded by the RPL35 gene . ref name pmid11401437 cite journal author Uechi T, Tanaka T, Kenmochi N title A complete map of the human ribosomal protein genes assignment of 80 genes to the cytogenetic map and implications for human disorders journal Genomics volume 72 issue 3 pages 223 30 year 2001 month Jun pmid 11401437 pmc doi 10.1006 geno.2000.6470 ref ref name entrez cite web title Entrez Gene RPL35 ribosomal protein L35 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 11224 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. ref name entrez References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Wool IG, Chan YL, Gl ck A title Structure and evolution of mammalian ribosomal proteins. journal Biochem. Cell Biol. volume 73 issue 11 12 pages 933 47 year 1996 pmid 8722009 doi 10.1139 o95 101 cite journal author Ou JH, Yen TS, Wang YF, et al. title Cloning and characterization of a human ribosomal protein gene with enhanced expression in fetal and neoplastic cells. journal Nucleic Acids Res. volume 15 issue 21 pages 8919 34 year 1988 pmid 2891103 doi 10.1093 nar 15.21.8919 pmc 306413 cite ... of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing ... more details
PBB geneid 6158 60S ribosomal protein L28 is a protein that in humans is encoded by the RPL28 gene . ref name pmid7772601 cite journal author Frigerio JM, Dagorn JC, Iovanna JL title Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs journal Biochim Biophys Acta volume 1262 issue 1 pages 64 8 year 1995 month Jul pmid 7772601 pmc doi ref ref name pmid9582194 cite journal author Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 issue 5 pages 509 23 year 1998 month Aug pmid 9582194 pmc doi 10.1101 gr.8.5.509 ref ref name entrez The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers ... of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal ... name entrez cite web title Entrez Gene RPL28 ribosomal protein L28 url http www.ncbi.nlm.nih.gov ... Structure and evolution of mammalian ribosomal proteins. journal Biochem. Cell Biol. volume 73 issue ..., Romualdi C, Danieli GA title Differential expression of genes coding for ribosomal proteins in different ... Differential expression of ribosomal proteins in human normal and neoplastic colorectum. journal ... modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman ... J title The composition of Staufen containing RNA granules from human cells indicates their role ... more details
PBB geneid 6223 40S ribosomal protein S19 is a protein that in humans is encoded by the RPS19 gene . ref ... TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 ... cite web title Entrez Gene RPS19 ribosomal protein S19 url http www.ncbi.nlm.nih.gov sites entrez ... are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal ... of patients. This suggests a possible extra ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels .... ref name entrez Interactions Ribosomal protein S19 has been shown to Protein protein interaction ... growth factor 2 interacts with free ribosomal protein S19 journal Biochem. Biophys. Res. Commun ... Leng, Richard Bucala, Sandra Kraemer, J rgen Bernhagen, and Andreas Meinhardt. Ribosomal Protein S19 ... Structure and evolution of mammalian ribosomal proteins journal Biochem. Cell Biol. volume 73 issue ... cite journal author Yamamoto T title Roles of the ribosomal protein S19 dimer and the C5a ... Kondoh N, Schweinfest CW, Henderson KW, Papas TS title Differential expression of S19 ribosomal protein ... ribosomal subunit proteins by N terminal and internal sequencing, and mass spectrometry journal Eur ... ribosomal protein S19 is mutated in Diamond Blackfan anaemia journal Nat. Genet. volume 21 issue 2 pages ... cite journal author Willig TN title Mutations in ribosomal protein S19 gene and diamond blackfan anemia ... first8 P last9 Garelli first9 E cite journal author Matsson H title Truncating ribosomal protein ... cells of an epithelial cell line, AsPC 1, release monocyte chemotactic S19 ribosomal protein ... factor 2 interacts with free ribosomal protein S19 journal Biochem. Biophys. Res. Commun. volume ... more details
nucleotides in eukaryotic ribosomalRNA journal Prog. Nucleic Acid Res. Mol. Biol. volume 39 issue pages 241 303 year 1990 pmid 2247610 doi 10.1016 S0079 6603 08 60629 7 ref . Small nucleolar RNA SNORA1 ACA1 , Small nucleolar RNA SNORA1 ACA8 , Small nucleolar RNA SNORA18 ACA18 , Small nucleolar RNA SNORA25 ACA25 , Small nucleolar RNA SNORA32 ACA32 and Small nucleolar RNA SNORA1 ACA40 and the C ...Infobox rfam Name Small nucleolar RNA SNORA40 image RF00561.jpg width caption Predicted secondary structure and sequence conservation of SNORA40 Symbol SNORA40 AltSymbols snoACA40 Rfam RF00561 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The small nucleolar RNA ACA40 belongs to the snoRNA H ACA family of snoRNAs and guides the pseudouridine pseudouridylation of rRNA 28S rRNA subunit at position U4565. snoRNA ACA40 was originally discovered using large scale Molecular cloning cloning by Kiss et al. 2004 ref name KISS04 cite journal last Kiss first AM coauthors Jady BE, Bertrand E, Kiss T year 2004 title Human box H ACA pseudouridylation guide RNA machinery journal Mol Cell Biol. volume 24 pages 5797&ndash 5807 pmid 15199136 doi 10.1128 MCB.24.13.5797 5807.2004 issue 13 pmc 480876 ref from a HeLa ... pseudouridylation of residues rRNA 28S rRNA U4546 and rRNA 18S rRNA 1174 ref name KISS04 ref ... screen for mammalian pseudouridylation guide H ACA RNAs journal RNA volume 12 issue 1 pages 15 25 year ... ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts ... External links Rfam id RF00561 name Small nucleolar RNA SNORA40 http www snorna.biotoul.fr plus.php?id ACA40 snoRNAbase entry for SNORA40 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA SNORA ... more details
PBB geneid 6124 60S ribosomal protein L4 is a protein that in humans is encoded by the RPL4 gene . ref name pmid9582194 cite journal author Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 issue 5 pages 509 23 year 1998 month Aug pmid 9582194 pmc doi 10.1101 gr.8.5.509 ref ref name pmid8268230 cite journal author Bagni C, Mariottini P, Annesi F, Amaldi F title Human ribosomal protein L4 cloning and sequencing of the cDNA and primary structure of the protein journal Biochim Biophys Acta volume 1216 issue 3 pages 475 8 year 1994 month Feb pmid 8268230 pmc doi ref ref name entrez cite web title Entrez Gene RPL4 ribosomal protein L4 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6124 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L4E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene ... of mammalian ribosomal proteins. journal Biochem. Cell Biol. volume 73 issue 11 12 pages 933 47 year ... structures of rat ribosomal proteins L4 and L41. journal Biochem. Biophys. Res. Commun. volume ... 3 cite journal author Twiss JL, Smith DS, Chang B, Shooter EM title Translational control of ribosomal ... T, Kenmochi N title A complete map of the human ribosomal protein genes assignment of 80 genes ... M, Uechi T, Asakawa S, et al. title The human ribosomal protein genes sequencing and comparative ... more details
Orphan date April 2012 RRNA RibosomalRNA rRNA intergenic spacer analysis RISA is a method of microbial community analysis that provides a means of comparing differing environments or treatment impacts without the bias imposed by culture dependent approaches. This type of analysis is often referred to as Community Fingerprinting community fingerprinting . RISA involves PCR amplification of a region of the rRNA gene operon between the small 16S and large 23S subunits called the intergenic spacer intergenic spacer region ISR. By using Oligonucleotide oligonucleotide primers targeted to conserved regions in the 16S and 23S genes, RISA fragments can be generated from most of the dominant bacteria in an environmental sample. While the majority of the rRNA operon serves a structural function, portions of the 16S 23S intergenic region can encode Transfer RNA tRNAs depending on the bacterial species. However the taxonomic value of the ISR lies in the significant heterogeneity in both length and nucleotide sequence. In RISA, we attempt to exploit the length heterogeneity of the ISR, which has been shown to range between 150 and 1500 bp with the majority of the ISR lengths being between 150 and 500 bp. The resulting PCR product will be a mixture of fragments contributed by several dominant community members. This product is electrophoresed in a polyacrylamide gel , and the DNA is visualized following staining. The result is a complex banding pattern that provides a community specific profile, with each DNA band corresponding to a bacterial population on the original assemblage. References references Borneman, J. and E.W. Triplett. 1997. Molecular microbial diversity in soils from eastern Amazonia evidence for unusual microorganisms and microbial population shifts associated with deforestation. Appl. Environ. Microbiol. 63 2647 2653. Sigler, W.V. and J. Zeyer. 2002. Microbial diversity and activity along the forefields of two receding glaciers Microb. Ecol. 43 397 407. Sigler, W.V. ... more details
PBB geneid 6160 60S ribosomal protein L31 is a protein that in humans is encoded by the RPL31 gene . ref name pmid2780320 cite journal author Nobori T, Hexdall LE, Carson DA title cDNA sequence of human ribosomal protein L31 journal Nucleic Acids Res volume 17 issue 17 pages 7105 year 1989 month Oct pmid 2780320 pmc 318439 doi 10.1093 nar 17.17.7105 ref ref name pmid11875025 cite journal author Yoshihama M, Uechi T, Asakawa S, Kawasaki K, Kato S, Higa S, Maeda N, Minoshima S, Tanaka T, Shimizu N, Kenmochi N title The human ribosomal protein genes sequencing and comparative analysis of 73 genes journal Genome Res volume 12 issue 3 pages 379 90 year 2002 month Mar pmid 11875025 pmc 155282 doi 10.1101 gr.214202 ref ref name entrez cite web title Entrez Gene RPL31 ribosomal protein L31 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6160 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L31E family of ribosomal proteins. It is located in the cytoplasm. Higher levels of expression of this gene in familial adenomatous ... ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome ... and evolution of mammalian ribosomal proteins. journal Biochem. Cell Biol. volume 73 issue 11 ..., Begent RH, et al. title Identification of a human ribosomal protein mRNA with increased expression ... S, et al. title A map of 75 human ribosomal protein genes. journal Genome Res. volume 8 issue 5 pages ... modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman ... more details
PBB geneid 6169 60S ribosomal protein L38 is a protein that in humans is encoded by the RPL38 gene . ref name pmid9582194 cite journal author Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 issue 5 pages 509 23 year 1998 month Aug pmid 9582194 pmc doi 10.1101 gr.8.5.509 ref ref name entrez cite web title Entrez Gene RPL38 ribosomal protein L38 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6169 accessdate ref Gene The human RPL38 gene resides on the long arm of chromosome 17 at 17q25.1. It consists of five exons spread out over a distance of 6223 bp. The 213 nucleotide open reading frame encodes a 70 amino acid protein . Alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogene s of this gene dispersed through the genome, including one located in the promoter region of the angiotensin II receptor type 1 gene. ref name entrez Function Ribosome s, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L38E family of ribosomal proteins. It is located in the cytoplasm .... ref cite pmid 15520262 ref In humans, mutations in ribosomal proteins cause Diamond Blackfan Anemia ... ribosomal proteins journal Biochem. Cell Biol. volume 73 issue 11 12 pages 933 947 year 1996 ..., lysine rich, ribosomal protein RPL38 and detection of an unusual RPL38 processed pseudogene in the promoter ... T, Kenmochi N title A complete map of the human ribosomal protein genes assignment of 80 genes to the cytogenetic ... ribosomal protein genes sequencing and comparative analysis of 73 genes journal Genome Res. volume ... more details
PBB geneid 9045 60S ribosomal protein L14 is a protein that in humans is encoded by the RPL14 gene . ref name pmid9480843 cite journal author Tanaka M, Tanaka T, Harata M, Suzuki T, Mitsui Y title Triplet repeat containing ribosomal protein L14 gene in immortalized human endothelial cell line t HUE4 journal Biochem Biophys Res Commun volume 243 issue 2 pages 531 7 year 1998 month Mar pmid 9480843 pmc doi 10.1006 bbrc.1998.8125 ref ref name entrez cite web title Entrez Gene RPL14 ribosomal protein L14 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 9045 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region leucine zipper bZIP like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide GCT repeat tract whose length is highly polymorphic these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5 terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed ... cite journal author Wool IG, Chan YL, Gl ck A title Structure and evolution of mammalian ribosomal ... ribosomal protein genes assignment of 80 genes to the cytogenetic map and implications for human ... The human ribosomal protein genes sequencing and comparative analysis of 73 genes. journal Genome ... modifications of the human large cytoplasmic ribosomal subunit proteins by mass ... more details
issue 2 ref and at homologous positions in mouse and chicken ribosomal protein genes. U35 is predicted to guide the 2 O ribose methylation of 28SribosomalRNA rRNA residue C4506 ref name pmid8764399 ...Infobox rfam Name Small nucleolar RNA SNORD35 image RF00211.jpg width caption Predicted secondary structure and sequence conservation of SNORD35 Symbol SNORD35 AltSymbols U35 Rfam RF00211 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA CD box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000593 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData snoRNA U35 also known as SNORD35 is a non coding RNA ncRNA molecule which functions in the modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA. snoRNA U35 belongs to the SnoRNA C.2FD box C D box class of snoRNAs which contain the conserved sequence motifs known as the C box UGAUGA and the D box CUGA . Most of the members of the box C D family function in directing site specific 2 O methylation of substrate RNAs ref name pmid12215523 cite journal last Galardi first S coauthors Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I year 2002 title Purified Box C D snoRNPs Are Able To Reproduce Site Specific 2 O Methylation of Target RNA In Vitro journal Mol Cell Biol volume 22 pages 6663&ndash 6668 pmid 12215523 doi 10.1128 MCB.22.19.6663 6668.2002 issue 19 pmc 134041 ref . U35 is encoded in intron 6 of ribosomal protein L13A and intron 3 of ribosomal ... ref . References references External links Rfam id RF00211 name Small nucleolar RNA SNORD35 http www snorna.biotoul.fr plus.php?id U35 snoRNABase entry for SNORD35 Small nucleolar RNA Category Small nuclear RNA molecular cell biology stub ... more details
Infobox rfam Name U8 small nucleolar RNA image RF00096.jpg width caption Predicted secondary structure and sequence conservation of U8 Symbol U8 AltSymbols CeN21 CeR 2 Rfam RF00096 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA CD box Tax domain Eukaryota GO GO 0005730 GO 0006396 SO SO 0000593 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData U8 small nucleolar RNA also known as SNORD118 is the RNA component of a small RNA protein complex the U8 snoRNP which is required for biogenesis of mature large subunit ribosomalRNA s, 5.8S and 28S rRNAs. ref name pmid9199304 cite journal author Peculis BA title The sequence of the 5 end of the U8 small nucleolar RNA is critical for 5.8S and 28S rRNA maturation journal Mol. Cell. Biol. volume 17 issue 7 pages 3702 13 year 1997 pmid 9199304 doi issn pmc 232222 ref ref name pmid11675000 cite journal author Peculis BA, DeGregorio S, McDowell K title The U8 snoRNA gene family identification and characterization of distinct, functional U8 genes in Xenopus journal Gene volume 274 issue 1 2 pages 83 92 year 2001 pmid 11675000 doi 10.1016 S0378 1119 01 00596 0 ref More specifically, U8 is a non coding RNA ncRNA molecule which functions in the modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA. snoRNA U8 belongs to the SnoRNA C.2FD box C D box class ... of target RNA in vitro journal Mol Cell Biol volume 22 pages 6663&ndash 6668 pmid 12215523 doi 10.1128 MCB.22.19.6663 6668.2002 issue 19 pmc 134041 ref U8 RNA genes have been identified in human ... name U8 small nucleolar RNA http www snorna.biotoul.fr plus.php?id U8 snoRNABase entry for SNORD118 Category Small nuclear RNA Small nucleolar RNA molecular cell biology stub ... more details
the 2 O ribose methylation of 28SribosomalRNA rRNA residue G4020. ref name pmid16381836 References reflist External links Rfam id RF00187 name Small nucleolar RNA SNORD102 http www snorna.biotoul.fr plus.php?id U102 snoRNABase entry for SNORD102 Small nucleolar RNA Category Small nuclear RNA molecular ...Infobox rfam Name Small nucleolar RNA SNORD102 image RF00187.jpg width caption Predicted secondary structure and sequence conservation of SNORD102 Symbol SNORD102 AltSymbols U102 Rfam RF00187 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA CD box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000593 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData snoRNA U102 also known as SNORD102 is a non coding RNA ncRNA molecule which functions in the modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA. snoRNA U102 belongs to the SnoRNA C.2FD box C D box class of snoRNAs which contain the conserved sequence motifs known as the C box UGAUGA and the D box CUGA . Most of the members of the box C D family function in directing site specific 2 O methylation of substrate RNAs. ref cite journal last Galardi first S coauthors Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I year 2002 title Purified Box C D snoRNPs Are Able To Reproduce Site Specific 2 O Methylation of Target RNA In Vitro journal Mol Cell Biol volume 22 pages 6663&ndash 6668 pmid 12215523 doi 10.1128 MCB.22.19.6663 6668.2002 issue 19 pmc 134041 ref U102 was identified by computational screening of the introns of ribosomal protein genes for conserved C D box sequence motifs and expression experimentally verified by northern blotting ... ref It is found within intron 2 of the L21 ribosomal protein gene. The SnoRNA H.2FACA box H ACA box ... more details
Infobox rfam Name Small nucleolar RNA SNORA17 image RF00560.jpg width caption Predicted secondary structure and sequence conservation of SNORA17 Symbol SNORA17 AltSymbols snoACA17 Rfam RF00560 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA HACA box Tax domain Eukaryota GO GO 0006396 GO 0005730 SO SO 0000594 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData In molecular biology , SNORA17 also known as ACA17 is a member of the H ACA class of small nucleolar RNA that guide the sites of modification of uridine s to pseudouridine s. ref name kiss 2004 cite journal last Kiss first AM coauthors Jady BE, Bertrand E, Kiss T year 2004 title Human box H ACA pseudouridylation guide RNA machinery journal Mol Cell Biol volume 24 pages 5797&ndash 5807 pmid 15199136 doi 10.1128 MCB.24.13.5797 5807.2004 issue 13 pmc 480876 ref Specifically, it is predicted to guide pseudouridylation of the 28S rRNA at positions U4659 and U4598. It shares the same host gene together with Small nucleolar RNA SNORA43 ACA43 . Interestingly, there are many closely related sequences that do not appear to have conserved H and ACA boxes, and may be pseudogenes. References reflist 1 cite journal last Ofengand first J coauthors Bakin A year 1997 title Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts journal J Mol Biol. volume 266 pages 246&ndash 268 pmid 9047361 doi 10.1006 jmbi.1996.0737 issue 2 External links Rfam id RF00560 name Small nucleolar RNA SNORA17 Category Small nuclear RNA molecular cell biology stub Small nucleolar RNA ... more details
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