PBB geneid 9619 ATP binding cassette sub family G member 1 is a protein that in humans is encoded by the ABCG1 gene . ref name pmid8659545 cite journal author Chen H, Rossier C, Lalioti MD, Lynn A, Chakravarti A, Perrin G, Antonarakis SE title Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3 journal Am J Hum Genet volume 59 issue 1 pages 66 75 year 1996 month Aug pmid 8659545 pmc 1915121 doi ref ref name pmid16870176 cite journal author Engel T, Bode G, Lueken A, Knop M, Kannenberg F, Nofer JR, Assmann G, Seedorf U title Expression and functional characterization of ABCG1 splice variant ABCG1 666 journal FEBS Lett volume 580 issue 18 pages ... cite web title Entrez Gene ABCG1 ATP binding cassette, sub family G WHITE , member 1 url http www.ncbi.nlm.nih.gov ... Schmitz G, Langmann T, Heimerl S title Role of ABCG1 and other ABCG family members in lipid metabolism ... G cite journal author Klucken J title ABCG1 ABC8 , the human homolog of the Drosophila white gene ... of the human ATP binding cassette transporter G1 ABCG1 gene journal Biochim. Biophys. Acta volume ... author Lorkowski S title Genomic sequence and structure of the human ABCG1 ABC8 gene journal Biochem ... repressor of ATP binding cassette transporter A1 ABCA1 and ABCG1 gene expression and a modulator ... Expression of the ATP binding cassette transporter gene ABCG1 ABC8 in Tangier disease journal Biochem ... of the human ABCG1 gene liver X receptor activates an internal promoter that produces ... induces expression of ABCA1 but not ABCG1 via an LXR independent pathway journal J. Lipid Res ... author Cserepes J title Functional expression and characterization of the human ABCG1 and ABCG4 ... Homolya first9 L szl refend External links MeshName ABCG1 protein, human NLM content ABC transporters ... summary yes update citations yes Category ABC transporters membrane protein stub de ABCG1 DEFAULTSORT Abcg1 ... more details
and characterization of the human ABCG1 and ABCG4 proteins indications for heterodimerization. journal ... of ABCG1 splice variant ABCG1 666 . journal FEBS Lett. volume 580 issue 18 pages 4551 9 year ... ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol rich ... more details
Infobox rfam Name miR 33a image Mir 33 SS.png width caption Conserved secondary structure of miR 33a microRNA precursor Symbol miR 33a AltSymbols mir33a Rfam RF00667 miRBase MI0000091 miRBase family MIPF0000070 RNA type miRNA Tax domain Metazoa GO 0035195 SO 0001244 CAS number EntrezGene 407039 HGNCid 31634 OMIM PDB RefSeq Chromosome 22 Arm q Band 13.2 LocusSupplementaryData Infobox rfam Name miR 33b image width caption Symbol miR 33b AltSymbols mir33b Rfam RF00667 miRBase MI0003646 miRBase family MIPF0000070 RNA type miRNA Tax domain Metazoa GO 0035195 SO 0001244 CAS number EntrezGene 693120 HGNCid 32791 OMIM PDB RefSeq Chromosome 17 Arm Band 13.2 LocusSupplementaryData lowercase miR 33 is a family of microRNA precursors, which are processed by the Dicer enzyme to give mature microRNAs. ref cite journal last Ambros first V year 2001 title microRNAs tiny regulators with great potential journal Cell volume 107 pages 823&ndash 826 pmid 11779458 doi 10.1016 S0092 8674 01 00616 X issue 7 ref miR 33 is found in several animal species, including human s. In some species there is a single member of this family which gives the mature product mir 33. In humans there are two members of this family called mir 33a and mir 33b, which are located in intron ic regions within two gene protein coding genes for Sterol regulatory element binding protein s SREBP 2 and SREBP 1 respectively. ref name Naj11 cite journal last Najafi Shoushtari first SH title MicroRNAs in cardiometabolic disease. journal Current atherosclerosis reports date 2011 Jun volume 13 issue 3 pages 202 7 pmid 21461683 doi 10.1007 s11883 011 0179 y ref Function miR 33 plays a role in lipid metabolism it downregulates a number of ABC transporter s, including ABCA1 and ABCG1 , which in turn regulate cholesterol and High density lipoprotein HDL generation. ref cite journal last Fern ndez Hernando first C coauthors Su rez, Y, Rayner, KJ, Moore, KJ title MicroRNAs in lipid metabolism. journal Current opinion in lipidology ... more details
Role of ABCG1 and other ABCG family members in lipid metabolism. journal J. Lipid Res. volume ..., ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8 journal J. Hum. Genet. volume 47 issue 6 ... more details
Infobox protein family Symbol ABC tran Name ABC Transporter image 1l7v opm.gif width caption Vitamin B sub 12 sub transporter, BtuCD PDB PDBe 1l7v Pfam PF00005 Pfam clan InterPro IPR003439 SMART PROSITE PDOC00185 MEROPS SCOP 1b0u TCDB 3.A.1 OPM family 17 OPM protein 3g5u CAZy CDD Image 3b60.gif thumb 300 right Lipid flippase MsbA Image 2onk.gif thumb 300 right Molybdate transporter AB sub 2 sub C sub 2 sub complex, open state ATP binding Gene cassette cassette transporters ABC transporter are members of a protein superfamily that is one of the largest and most ancient families with representatives in all extant taxon extant Phylum phyla from prokaryote s to humans. ref name Jones2004 cite journal author Jones PM, George AM title The ABC transporter structure and mechanism perspectives on recent research journal Cell Mol Life Sci. volume 61 issue 6 pages 682 99 year 2004 month Mar pmid 15052411 doi 10.1007 s00018 003 3336 9 ref ref name Ponte SucreA cite book author Ponte Sucre, A editor year 2009 title ABC Transporters in Microorganisms publisher Caister Academic Press isbn 978 1 904455 49 3 ref ABC transporters are transmembrane protein s that utilize the energy of adenosine triphosphate ATP hydrolysis to carry out certain biological processes including translocation of various substrates across membranes and non transport related processes such as translation of RNA and DNA repair. ref name davidson cite journal doi 10.1128 MMBR.00031 07 author Davidson A.L., Dassa E., Orelle C., Chen J. year 2008 title Structure, function, and evolution of bacterial ATP binding cassette systems journal Microbiol. Mol. Biol. Rev. volume 72 issue 2 pages 317 364 pmid 18535149 pmc 2415747 ref ref name goffeau Goffeau, A. B. de Hertogh and P.V. Baret. 2004. ABC Transporters. In Encyclopedia of Biological Chemistry. Vol. 1, 1 5. ref They transport a wide variety of substrates across extra and intracellular cell membrane membranes , including metabolism metabolic products, lipid s and ... more details
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