Advert date October 2010 reason The 1st 3 paragraphs appear to have been copied from Symyx advertising. Update date October 2010 reason Company is defunct, having merged with Accelrys Infobox company infobox source http www.symyx.com company name Symyx Technologies company logo Image Symyx logo.JPG 214px Symyx Technologies foundation 1994 location Santa Clara, CA USA key people Isy Goldwasser , CEO br Steven D. Goldby , Executive Chairman br Rex S. Jackson , Executive Vice President and General Counsel br W. Henry Weinberg Ph.D. , Executive Vice President and CTO industry Life Sciences Chemical and Energy and Performance Materials and Consumer Products products Electronic lab notebook and R&D execution and analysis software, lab automation and breakthrough materials technology num employees 400 homepage http accelrys.com accelrys.com Symyx Technologies was a company specializing in the area of combinatorial chemistry and is now part of Accelrys . Symyx offers high speed combinatorial technologies for the discovery of new materials. Using proprietary technologies including instruments, software and methods enabled Symyx to generate hundreds to thousands of unique materials at a time and screen those materials rapidly and automatically for desired properties. This approach can deliver results hundreds to thousands of times faster than traditional research methods, at a fraction of the cost. ref cite web url http www.healthtech.com news strategic briefings 2007 Symyx.asp title Symyx Technologies & Pharmaceutical R&D A Synergistic Combo date 2007, July dead link date October 2010 ref Symyx is applying this technology to revolutionize materials discovery in the life sciences, chemical, and electronics industries. Founded in 1994 by Dr. Alejandro Zaffaroni and Dr. Peter G. Schultz , Symyx conceptual basis draws from Affymax , Inc. and Affymetrix , Inc., which commercialized the use of high speed combinatorial methods for pharmaceutical and genetics genetic research, respe ... more details
Image Mostafa Ronaghi.jpg thumb right Mostafa Ronaghi Mostafa Ronaghi born 1968 , is an Iranian molecular biologist , specializing in DNA sequencing methodology . He earned his Ph.D. from the Royal Institute of Technology in Sweden in 1998. He is currently the Chief Technology Officer and Senior Vice President at Illumina company Illumina . ref http investor.illumina.com phoenix.zhtml?c 121127&p irol newsArticle&ID 1182777&highlight Illumina 2008 Release Illumina Appoints Mostafa Ronaghi as Senior Vice President and Chief Technology Officer ref Prior to this position, he was a principal investigator and Senior Research Associate at the Stanford Genome Technology Center at Stanford University , focusing on developing analytical techniques for molecular diagnostics. He is principal investigator for several grants including grants from the National Human Genome Research Institute NHGRI , part of the National Institutes of Health ref http www.genome.gov 12513210 genome.gov 2004 Release NHGRI Seeks Next Generation of Sequencing Technologies Bot generated title ref for the development of array based Pyrosequencing . He is an inventor of Pyrosequencing technology and co founded Pyrosequencing AB in 1997 renamed to Biotage in 2003 , and co invented Molecular Inversion Probe assay and co founded ParAllele BioScience to develop this multiplexed technology for genetic testing. ParAllele was acquired by Affymetrix in May 2005. In 2005, he co founded Nextbio , a search engine for life science data. He also serves on the board of directors of IntegenX and Aurora Biofuels. In 2008 he co founded Avantome , a DNA sequencing company acquired by Illumina July 2008. ref http www.tradingmarkets.com .site news Stock 20News 1775391 tradingmarkets.com 2008 Release Illumina To Acquire Privately Held Avantome For 25 Million In Cash Upfront ref Publications Among his approximately 50 peer reviewed journal articles are the publications describing Pyrosequencing and Molecular Inversion Probe as ... more details
on the analysis of single channel Affymetrix and two or more channel Complementary DNA cDNA Oligonucleotide ... for pre processing Affymetrix and Complementary DNA cDNA array data identifying Expression profiling ... DNA Microarray Affymetrix , a microarray technology platform External links Official website http www.bioconductor.org ... more details
SickKids built a new Affymetrix microarray facility. This core has quickly grown to become the largest such service centre in Canada and is in the top ten in North America. ref Data provided by Affymetrix ... and Gene Expression Core Facility has a dedicated manager, and operates Affymetrix and Agilent ... Genomics Genetic and Statistical Analysis Genetic Analysis Core Facility . Affymetrix MegAllele and Single nucleotide polymorphism Single Nucleotide Polymorphism SNP DNA microarray microarrays , Affymetrix ... more details
This is a list of organization s involved in genetics research or related activities. Companies Affymetrix , United Kingdom UK http www.affymetrix.com Applera , Norwalk, Connecticut Norwalk , Connecticut CT http www.applera.com Applied Biosystems , Foster City, California Foster City , California CA http www.appliedbiosystems.com Asper Asper Biotech http www.asperbio.com Celera Genomics Genentech , San Francisco , California CA http www.gene.com Genetix, Hampshire , United Kingdom UK http www.genetix.com Research institutes Africa Kenya International Livestock Research Institute ILRI , Nairobi , http www.cgiar.org Asia Pacific Australia Commonwealth Scientific and Industrial Research Organisation http www.csiro.au India Centre for population genetics, KolKatta Department of Genetics, Dr. ALM. PG. IBMS, University of Madras Institute of Forest Genetics and Tree Breeding IFGTB , http ifgtb.icfre.gov.in Hong Kong Chinese University of Hong Kong s Department of Biology, http www.bio.cuhk.edu.hk bio Hong Kong Institute of Biotechnology , http www.hkib.org.hk Institute of Molecular Biology, Hong Kong , http www.hku.hk hkuimb China Beijing Genomics Institute Chinese National Human Genome Center Singapore Biopolis, Singapore http www.biopolis.com.sg Genome Institute of Singapore http www.gis.a star.edu.sg Bioinformatik Institute, Singapore http www.bii sg.org Institute of Molecular and Cell Biology Singapore Institute of Molecular and Cell Biology http www.imcb.a star.edu.sg Bioinformatics Center, Singapore http www.bic.nus.edu.sg Taiwan National Health Research Institutes http www.nhri.org.tw Japan National Institute of Genetics http www.nig.ac.jp index e.html Kazusa DNA Research Institute http www.kazusa.or.jp e index.html RIKEN http www.riken.go.jp Canada Canada s Michael Smith Genome Sciences Centre, Vancouver , British Columbia http www.bcgsc.bc.ca McGill University and G nome Qu bec Innovation Centre, Montreal , Quebec http www.genomequebecplatforms.com mcgill home index.aspx ... more details
In bioinformatics , a genome browser is a graphical interface for display of information from a biological database for genomic data. Genome browsers enable researchers to visualize and browse entire genomes most have many complete genomes with annotated data including gene prediction and structure, proteins, expression, regulation, variation, comparative analysis, etc. Annotated data is usually from multiple diverse sources. They differ from ordinary biological databases in that they display data in a graphical format, with genome coordinates on one axis and the location of annotations indicated by a space filling graphic to show the occurrence of genes, etc. List of genome browsers PLEASE KEEP IN ALPHABETICAL ORDER http annmap.picr.man.ac.uk Annmap A genome browser that shows Affymetrix Exon Microarray hit locations alongside the gene , transcript and exon data on a Google Maps API http apollo.berkeleybop.org current index.html Apollo Genome Annotation Curation Tool A cross platform, Java based standalone genome viewer with enterprise level functionality and customizations. The standard for many model organism databases. ref cite pmid 12537571 ref http www.broad.mit.edu annotation argo Argo Genome Browser A free and open source standalone Java based genome browser for visualizing and manually annotating whole genomes. ref cite pmid 16709588 ref http www.avadis ngs.com features genome browser Avadis NGS combines a genome browser and set of data analysis tools for ChIP Seq , RNA Seq , and genomic variation experiments, developed by Strand Life Sciences http doolittle.ibls.gla.ac.uk leader BugView index.html BugView Free cross platform desktop browser for visualizing genomes, especially suited for comparing prokaryotic genomes. http sourceforge.net projects celeragb files Celera Genome Browser , developed at Celera Genomics as part of Celera s sequencing and annotation of the human genome, and released as open source in 2006. http www.biodalliance.org Dalliance Javas ... more details
as 70 Microarrays, Inc. to 25 mers Affymetrix . Feb 2007 Probe composition There are tiled and non ... genome. ref name M.J. Buck, J.D. Lieb 2004 Nowadays, Affymetrix offers whole genome tiled yeast ... more and more powerful, too. Just to name example, Affymetrix offers a set of seven arrays with about ... wiki ChIP chip List of ChIP chip software Wikiomics OpenWetWare http www.chiponchip.net Affymetrix ... more details
Infobox Person name Dietrich Stephan birth date Birth date 1969 08 25 birth place Pittsburgh, Pennsylvania Pittsburgh , Pennsylvania known for Co founder of Navigenics , Amnestix, and Aueon Founder of Ignite Institute for Individualized Health occupation Human Geneticist nationality United States American Dr. Dietrich Stephan , Ph.D. born August 25, 1969 is an American human geneticist and co founder of Navigenics , ref http www.navigenics.com visitor about us team executives dietrich stephan Stephan s profile on Navigenics ref a personal genetics company. He is also the President and CEO of the Ignite Institute for Individualized Health. Early life Dietrich Stephan was born in Pittsburgh, Pennsylvania Pittsburgh , Pennsylvania . He received his B.S. in Biology Biochemistry from Carnegie Mellon University in 1991. He went on to obtain his Ph.D. in Human Molecular Genetics in 1996 from the University of Pittsburgh . Stephan completed a fellowship in 1999 at the National Human Genome Research Institute. ref name aaas.org http www.aaas.org spp PM bios ref Academic career Stephan s career spans research and academia to entrepreneurship. He has held faculty positions at Johns Hopkins University , George Washington University , Arizona State University , University of Arizona , the National Human Genome Research Institute of the NIH and the Children s National Medical Center . During his time at the NIH, Stephan researched and published extensive information on the genetic components of common cancers such as prostate cancer and breast cancer. ref name aaas.org In 2003, Stephan was an early recruit to the Translational Genomics Research Institute TGen in Phoenix, Arizona as a Senior Investigator and founding Chairman of the Department of Neurogenomics. He later served as the Deputy Director of Discovery Research at TGen, where he oversaw the research program. During his time at TGen, Stephan and his colleagues were some of the first to use the Affymetrix gene chip platfor ... more details
Infobox rfam Name CrfA RNA image CrfA SScons.png width 220px caption Conserved secondary structure of CrfA RNA. Symbol CrfA AltSymbols Rfam RNA type Tax domain Caulobacter CrfA RNA C aulobacter r esponse to f amine RNA is a family of non coding RNA s found in Caulobacter crescentus . CrfA is gene expression expressed upon carbon starvation and is thought to activate 27 gene s. ref name Lan10 cite journal author Landt SG, Lesley JA, Britos L, Shapiro L title CrfA, a Small Noncoding RNA Regulator of Adaptation to Carbon Starvation in Caulobacter crescentus journal J. Bacteriol. volume 192 issue 18 pages 4763 75 year 2010 month September pmid 20601471 doi 10.1128 JB.00343 10 url http jb.asm.org cgi pmidlookup?view long&pmid 20601471 accessdate 2010 09 01 pmc 2937403 ref It was originally identified along with Caulobacter crescentus Genomics 26 other non coding RNAs using a tiled Caulobacter microarray protocol specifically aimed at detecting small RNAs. ref name Lan08 cite journal author Landt SG, Abeliuk E, McGrath PT, Lesley JA, McAdams HH, Shapiro L title Small non coding RNAs in Caulobacter crescentus journal Mol. Microbiol. volume 68 issue 3 pages 600 14 year 2008 month May pmid 18373523 doi 10.1111 j.1365 2958.2008.06172.x url http www3.interscience.wiley.com resolve openurl?genre article&sid nlm pubmed&issn 0950 382X&date 2008&volume 68&issue 3&spage 600 accessdate 2010 09 01 ref CrfA RNA is one of only 8 putative ncRNAs conserved in the closely related Caulobacter species K31 Caulobacter sp. K31 . ref name Lan10 Carbon starvation response CrfA was found to be upregulated 10 fold in C. crescentus when glucose was deprived in a growth medium minimal medium . Further experimentation found the response to be specific to carbon deprivation its expression was not increased when phosphate or nitrogen were limiting factor s. ref name Lan10 Affymetrix DNA microarry microarrays were then used to analyse changes in the transcriptome in response to increased CrfA. Seven af ... more details
Infobox rfam Name RNA anti toxin A image RatA SScons.png width 220px caption Conserved secondary structure of RatA antitoxin sRNA. Symbol RatA AltSymbols Rfam RF01776 RNA type Antisense RNA Antisense Tax domain Firmicutes The TxpA RatA toxin antitoxin system was first identified in Bacillus subtilis . ref name Sil05 cite journal author Silvaggi JM, Perkins JB, Losick R title Small untranslated RNA antitoxin in Bacillus subtilis journal J. Bacteriol. volume 187 issue 19 pages 6641 50 year 2005 month October pmid 16166525 pmc 1251590 doi 10.1128 JB.187.19.6641 6650.2005 url http jb.asm.org cgi pmidlookup?view long&pmid 16166525 accessdate 2010 09 16 ref It consists of a non coding RNA non coding 222nt sRNA called RatA RNA a nti t oxin A and a protein toxin named TxpA Toxic protein A . ref name Foz10 cite journal author Fozo EM, Makarova KS, Shabalina SA, Yutin N, Koonin EV, Storz G title Abundance of type I toxin antitoxin systems in bacteria searches for new candidates and discovery of novel families journal Nucleic Acids Res. volume 38 issue 11 pages 3743 59 year 2010 month June pmid 20156992 pmc 2887945 doi 10.1093 nar gkq054 url http nar.oxfordjournals.org cgi pmidlookup?view long&pmid 20156992 accessdate 2010 09 16 ref RatA was discovered in intergenic regions of the B. subtilis genome , in a 728 nucleotide region between genes yqdB later renamed TxpA and yqbM . Initially, Affymetrix DNA microarray microarrays were used to detect transcription genetics transcription in this region, ref cite journal author Lee JM, Zhang S, Saha S, Santa Anna S, Jiang C, Perkins J title RNA expression analysis using an antisense Bacillus subtilis genome array journal J. Bacteriol. volume 183 issue 24 pages 7371 80 year 2001 month December pmid 11717296 pmc 95586 doi 10.1128 JB.183.24.7371 7380.2001 url http jb.asm.org cgi pmidlookup?view long&pmid 11717296 accessdate 2010 09 16 ref Northern blot experiments and mutation analysis were then employed to characterise the RNA transcript ... more details
inbred strain s. By early 2003, the first large Affymetrix gene expression data sets whole mouse ... annotation files for several RNA profiling platforms Affymetrix, Illumina, and Agilent . RNA seq data ... more details
compatible Status with the Affymetrix GeneChip Microarray Platform publisher Business Wire date ...... a0144053717 ref with the Affymetrix Inc. GeneChip microarray platform. SBT launched an SaaS ... more details
The NASDAQ Biotechnology Index includes securities of NASDAQ listed companies classified according to the Industry Classification Benchmark as either Biotechnology or Pharmaceuticals . Criteria In order to remain included within the index, the components must meet the following criteria The security U.S. listing must be exclusively on the NASDAQ National Market unless the security was dually listed on another U.S. market prior to January 1, 2004 and has continuously maintained such listing . The issuer of the security must be classified according to the Industry Classification Benchmark as either Biotechnology or Pharmaceuticals. The security may not be issued by an issuer currently in bankruptcy proceedings. The security must have a market capitalization of at least 200 million. The security must have an average daily trading volume of at least 100,000 shares. The issuer of the security may not have entered into a definitive agreement or other arrangement which would likely result in the security no longer being Index. The issuer of the security may not have annual financial statements with an audit opinion that is currently withdrawn. The issuer of the security must have seasoned on NASDAQ or another recognized market for at least 6 months in the case of spin offs, the operating history of the spin off will be considered. Components Update after 2012 05 This list of 119 companies is current as of 24 January 2012. The list reviewed twice annually in May and November, although components may be removed at any time. Achillion Pharmaceuticals Inc. NASDAQ ACHN Acorda Therapeutics Inc. NASDAQ ACOR Affymetrix Inc. NASDAQ AFFX Affymax Inc. NASDAQ AFFY Akorn Inc. NASDAQ AKRX Alkermes plc NASDAQ ALKS Alnylam Pharmaceuticals Inc. NASDAQ ALNY AMAG Pharmaceuticals Inc. NASDAQ AMAG Amgen Inc. NASDAQ AMGN Amylin Pharmaceuticals Inc. NASDAQ AMLN Amarin Corporation plc NASDAQ AMRN ARIAD Pharmaceuticals Inc. NASDAQ ARIA Arena Pharmaceuticals Inc. NASDAQ ARNA ArQule Inc. NASDAQ ARQL ... more details
Encyclopedia
top
