This article is about the medical condition. For the moth genus , see Asplenia moth . For spleenwort fern s, see Asplenium . Infobox disease Name Asplenia Image Caption DiseasesDB ICD10 ICD10 D 73 0 d 70 , ICD10 Q 89 0 q 80 ICD9 ICD9 289.59 , ICD9 759.01 ICDO OMIM 208530 OMIM mult OMIM2 271400 OMIM2 208540 MedlinePlus eMedicineSubj ped eMedicineTopic 150 eMedicine mult eMedicine2 radio 58 MeshID Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks. Hyposplenism is used to describe reduced hypo splenic functioning, but not as severely affected as with asplenism. Causes Congenital Congenital asplenia rare may be due to genetic disorders, i.e. heterotaxy syndrome . Acquired Acquired disorder Acquired asplenia occurs for several reasons Following splenectomy due to splenic rupture from Physical trauma trauma or because of tumor After splenectomy with the goal of interfering with splenic function, as a treatment for diseases e.g. idiopathic thrombocytopenic purpura , thalessemia , spherocytosis , in which the spleen s usual activity exacerbates the disease Due to underlying diseases that destroy the spleen autosplenectomy , e.g. sickle cell disease . Functional asplenia occurs when splenic tissue is present but does not work well, e.g. sickle cell disease, polysplenia such patients are managed as if asplenic. Partial splenectomy ... This may be particularly important in poorer countries where protective measures for patients with asplenia ... ref Risks Asplenia is a form of immunodeficiency , increasing the risk of sepsis from polysaccharide ... at birth, for congenital asplenia or functional asplenia . The duration suggested varies one ... with asplenia or splenic dysfunction title Immunisation against infectious disease The Green Book ... Spleens year 2004 url http www.medik.info MI Asplenia OPSI.doc format DOC publisher Medik.Info patient ... it Asplenia nl Asplenie pl Asplenia pt Asplenia fi Asplenia ... more details
DISPLAYTITLE Asplenia moth Taxobox image regnum Animal ia phylum Arthropod a classis Insect a ordo Lepidoptera familia Noctuidae subfamilia Catocalinae genus Asplenia genus authority Hampson, 1916 synonyms Asplenia small Hampson, 1926 small Asplenia is a genus of moth s of the Noctuidae family. Species Asplenia melanodonta small Hampson, 1896 small References http www.nic.funet.fi pub sci bio life insecta lepidoptera ditrysia noctuoidea noctuidae catocalinae asplenia index.html Asplenia at funet.fi http www.nhm.ac.uk jdsml research curation projects butmoth GenusList3.dsml?searchPageURL index.dsml&SUPERFAMIL &FAMILYqtype starts with&FAMILY noctuidae&SUBFAMILYqtype starts with&SUBFAMILY &TRIBEqtype starts with&TRIBE &SUBTRIBEqtype starts with&SUBTRIBE &GENUSqtype starts with&GENUS &AUTHORqtype starts with&AUTHOR &YEARqtype equals&YEAR &sort GENUS Natural History Museum Lepidoptera genus database DEFAULTSORT Asplenia Moth Category Armadini Catocalinae stub ... more details
This article was auto generated by User Polbot . Taxobox name Caudacaecilia asplenia image status DD status system IUCN3.1 regnum Animalia phylum Chordata classis Amphibia ordo Gymnophiona familia Ichthyophiidae genus Caudacaecilia species C. asplenia binomial Caudacaecilia asplenia binomial authority Edward Harrison Taylor Taylor , 1965 synonyms Caudacaecilia asplenia is a species of amphibian in the Ichthyophiidae family. It is found in Malaysia and possibly Thailand . Its natural habitat s are subtropical or tropical moist lowland forest s, river s, intermittent rivers, plantation s , rural gardens, heavily degraded former forest, irrigated land, and seasonally flooded agricultural land. Source van Dijk, P.P., Sukumaran, J., Yaakob, N., Chuaynkern, Y., Wilkinson, M., Gower, D. & Kupfer, A. 2004. http www.iucnredlist.org search details.php 59602 all Caudacaecilia asplenia . http www.iucnredlist.org 2006 IUCN Red List of Threatened Species. Downloaded on 22 July 2007. caecilian stub Category Caudacaecilia Category Animals described in 1965 Category Amphibians of Malaysia es Caudacaecilia asplenia fr Caudacaecilia asplenia pt Caudacaecilia asplenia vi Caudacaecilia asplenia ... more details
Infobox disease Name Asplenia with cardiovascular anomalies Image Alt Caption DiseasesDB ICD10 ICD9 ICDO OMIM 208530 MedlinePlus eMedicineSubj eMedicineTopic MeshID Asplenia with cardiovascular anomalies or Ivemark syndrome , also known as Right Atrial Isomerism , ref name patientuk cite web url http www.patient.co.uk showdoc 26740304 title Ivemark Syndrome Association work Patient UK date 2008 11 10 accessdate 2009 05 27 ref is an example of a Situs ambiguus heterotaxy syndrome . These uncommon congenital disorders are characterized by defects in the heart, spleen and paired organs such as the lungs and kidneys. Another name is asplenia cardiovascular defect heterotaxy . ref Cite journal last1 Konstantinidou first1 A. last2 Sifakis first2 S. last3 Koukoura first3 O. last4 Mantas first4 N. last5 Agrogiannis first5 G. last6 Patsouris first6 E. title Pancreatic aplasia in a fetus with asplenia cardiovascular defect heterotaxy Ivemark syndrome . journal Birth Defects Res A Clin Mol Teratol volume 82 issue 8 pages 601 4 month Aug year 2008 doi 10.1002 bdra.20467 PMID 18496831 ref Right atrial isomerism is named for its discoverer, the Swedish pathologist Bi rn Ivemark . ref Cite journal last1 IVEMARK first1 BI. title Implications of agenesis of the spleen on the pathogenesis of conotruncus anomalies in childhood an analysis of the heart malformations in the splenic agenesis syndrome, with fourteen new cases. journal Acta Paediatr Suppl volume 44 issue Suppl 104 pages 7 110 month Nov year 1955 doi PMID 13292296 ref Presentation In right atrial isomerism, both atria of the heart are morphological right atria leading to associated abnormalities in the pulmonary venous system. In addition, individuals with right atrial isomerism develop asplenia , a mid line liver, malrotation of the small intestine and the presence of two morphologic right lungs. Individuals with left atrial isomerism, by comparison, have two morphologic left atria, polysplenia , intestinal malrotation and two ... more details
Unreferenced date January 2007 orphan date November 2009 Taxobox name Armadini regnum Animal ia phylum Arthropod a subphylum Hexapoda classis Insect a ordo Lepidoptera superfamilia Noctuoidea familia Noctuidae subfamilia Catocalinae tribus Armadini tribus authority subdivision ranks Genus Genera subdivision Metoponrhis br Epharmottomena br Drasteriodes br Iranada br Riadhia br Metopistis br Asplenia moth Asplenia br Armada moth Armada br Tarachephia The Armadini are a noctuidae noctuid owlet moth tribe biology tribe of the Catocalinae subfamily . As numerous catocaline genera have not yet been assigned to a tribe, the genus list should be considered preliminary. Category Catocalinae Category Armadini Catocalinae stub es Armadini ... more details
or cytomegalovirus . Other infections should be excluded if these tests are negative. Asplenia Main AspleniaAsplenia is the absence of normal spleen function. It predisposes to some sepsis septicemia ... this is rare. Sickle cell disease can cause a functional asplenia or autosplenectomy by causing infarction ... more details
An autosplenectomy from auto self, splen spleen, List of ectomies ectomy removal occurs when a disease damages the spleen to such an extent that it becomes shrunken and non functional. ref http library.med.utah.edu WebPath HEMEHTML HEME116.html Autosplenectomy with sickle cell anemia, gross at http library.med.utah.edu WebPath WebPath , The Internet Pathology Laboratory for Medical Education at Mercer University School of Medicine. Retrieved September 10, 2011 ref Consequences Main Asplenia Absence of effective splenic function asplenia is associated with increased risks of overwhelming post splenectomy infection , especially by encapsulated organisms. Protocols involving vaccination and Prophylaxis prophylactic antibiotics can reduce these risks. Diseases that cause autosplenectomy Sickle cell anemia Sickle cell anemia causes autosplenism by causing hypoxia and infarcts in the spleen. Since in the spleen blood flow is sluggish, the oxygen tension is low. When red blood cells with hemogblobin S are exposed to this low oxygen tension they tend to aggregate and polymerize. Sickled cells also express more adhesion molecules and appear more sticky. The sickle cells arrest in the hypoxic vascular bed in the spleen, resulting in a vicious cycle decrease in O2, sickling and vascular obstruction from thrombus formation. Initially the spleen is enlarged, then progressively becomes smaller. The stasis of flow in the spleen causes hypoxic damage, thrombosis, infarction and fibrosis. In the end the spleen disappears completely termed autosplenectomy . References reflist Category Immune system disorders Category Lymphatic organ diseases Immunology stub ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB 32864 ICD10 ICD10 Q 89 0 q 80 ICD9 ICD9 759.0 ICDO OMIM MedlinePlus eMedicineSubj ped eMedicineTopic 2514 MeshID Polysplenia is a congenital disease manifested by multiple small accessory spleen s. ref DorlandsDict seven 000085247 polysplenia ref Associated conditions There are frequent associated congenital anomalies all related to deviations in the development of anatomical asymmetries in early embryonic stages. These conditions considered together are called polysplenia syndrome . ref DorlandsDict eight 000104623 polysplenia syndrome ref Associated conditions include heterotaxy syndrome , intestinal malrotation , situs inversus , biliary atresia , and the range of congenital cardiac malformations. Although present, the multiple small spleens are ineffective this is termed functional asplenia . References reflist disease stub Splenic disease Category Lymphatic organ diseases es Poliesplenia it Polisplenia ... more details
Bi rn sic Bi rn and not Bj rn Ivemark born 1925 in Karlstad , died May 8, 2005 in Carcassonne was a Swedish pediatrician and pathologist. He is credited with characterizing Asplenia with cardiovascular anomalies , also sometimes known as Ivemark syndrome . ref http www.steadyhealth.com encyclopedia Ivemark s syndrome Steadyhealth Ivemark s syndrome ref Ivemark graduated from Karolinska Institutet with a med.lic. degree in 1951 and received his research doctorate in 1955. ref Ivemark, Bi rn I., Implications of agenesis of the spleen on the pathogenesis of cono truncus anomalies in childhood An analysis of the heart malformations in the splenic agenesis syndrome, with fourteen new cases , Diss. Stockholm Karol. inst.,Stockholm, 1955 LIBRIS http libris.kb.se bib 1453830 record ref References Reflist Persondata Metadata see Wikipedia Persondata . NAME Ivemark, Bjorn ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 1925 PLACE OF BIRTH DATE OF DEATH May 8, 2005 PLACE OF DEATH DEFAULTSORT Ivemark, Biorn Category 1925 births Category 2005 deaths Category Swedish physicians Category Pediatricians Category Pathologists Category Karolinska Institutet alumni med bio stub de Bj rn Ivemark fr Bj rn Ivemark pl Bj rn Ivemark sv Bi rn Ivemark ... more details
Howell Jolly bodies are histopathology histopathological findings of basophilic cell nucleus nuclear remnants clusters of DNA in circulating erythrocytes . During maturation in the bone marrow erythrocytes normally expel their nuclei, but in some cases a small portion of DNA remains. It is named for William Henry Howell and Justin Marie Jolly . ref WhoNamedIt synd 1596 ref ref W. H. Howell. The life history of the formed elements of the blood , especially the red blood corpuscles. Journal of Morphology, New York, 1890 91, 4 57 116. ref ref J. M. J. Jolly. Sur la formation des globules rouges des mammif res. Comptes rendus de la Soci t de Biologie, Paris, 1905, 58 528 531. ref Appearance File Howell Jolly smear 2010 11 17.JPG thumb right Howell Jolly bodies small, round inclusions seen in erythrocytes. Peripheral blood MGG stain This DNA appears as a basophilic purple spot on the otherwise eosinophilic pink erythrocyte on a standard H&E stain ed blood smear. These inclusions are normally pitted out by the spleen during erythrocyte circulation, but will persist in individuals with functional hyposplenia or asplenia . Causes Common causes of asplenia are splenectomy following Physical trauma trauma to the spleen, and autosplenectomy caused by sickle cell anemia . Ten percent of patients with Coeliac disease also present with splenic atrophy with subsequent Howell Jolly bodies. Other causes are radiation therapy involving the spleen, such as that used to treat Hodgkin lymphoma . Howell Jolly bodies are also seen in severe hemolytic anemia , megaloblastic anemia , hereditary spherocytosis , and myelodysplastic syndrome MDS . References reflist External links http www.academic.marist.edu jzmz topics inclusions inclusions18.html Link currently not functional http www.brown.edu Courses Digital Path systemic path heme howelljolly.html pathology stub Abnormal clinical and laboratory findings Eponymous medical signs for hematology and oncology Category Abnormal clinical and l ... more details
, and the meningococcal vaccine see asplenia . These bacteria often cause a sore throat under normal ... typically have Howell Jolly bodies ref WhoNamedIt synd 1596 ref ref Katcher AL. Familial asplenia ... and antibiotics provide good protection against the risks of asplenia, this is not always available ... 9660206 doi 10.1016 S0022 3468 98 90651 0 ref See also Asplenia Lymphatic system Autosplenectomy Infectious ... more details
Refimprove date July 2007 Target cell is a term given to one of three different concepts in medicine. Hematology In hematology , target cells are very abnormal red blood cells , that have a bullseye target bullseye appearance See main article codocyte . These target cells from red blood cells are associated with Hemoglobin C HbC disease, Asplenia , Liver Disease , Thalassemia and severe Iron deficiency anemia . Target cells may be seen on a peripheral blood smear when there is excess membrane relative to the amount of hemoglobin. Membrane may be excessive in liver disease. Intracellular hemoglobin may be lowered during iron deficiency, thalassemia, hemoglobin C or SC and other hemoglobinopathies. Immunology In immunology , target cells are cells which present the antigen antigenic peptide combined with MHC class I molecules to Cytotoxic T cell s. These cells have MHC molecules on their surface in contrast to Antigen Presenting Cell s, which in addition also have MHC class II molecules . Target Cells are the normal cells of the body which have undergone some alteration and synthesize abnormal proteins e.g. tumor cells, virus infected cells. Endocrinology In endocrinology , target cells can refer to the cells where hormone s have their effect. Target cells are capable of responding to hormones because they bear Receptor biochemistry receptors to which the hormone can bind. Most hormones circulate in blood, coming into contact with essentially all cells. However, a given hormone usually affects only a limited number of cells, which are called target cells. A target cell responds to a hormone because it bears receptors for the hormone. Hormone receptors are found either exposed on the surface of the cell or within the cell, depending on the type of hormone. A hormone may bind target cells in three general ways Endocrine action the hormone is distributed in blood and binds to distant target cells. Paracrine action the hormone acts locally by diffusing from its source to ... more details
to encapsulated bacterial infections. Asplenia People that lack a spleen , functionally as in sickle ... with asplenia are vaccine vaccinated against N eisseria meningitis , H aemophilus influenzae , and S treptococcus ... more details
italic title Taxobox name Capnocytophaga regnum Bacteria phylum Bacteroidetes phylum Bacteroidetes classis Flavobacteria ordo Flavobacteriaceae familia Flavobacteriaceae genus Capnocytophaga species C. canimorsus species authority Brenner et al. , 1990 binomial Capnocytophaga canimorsus Capnocytophaga canimorsus is a Gram negative bacillus rod shaped bacterium that causes a zoonotic disease , most commonly in asplenia asplenic patients . It is a member of the normal gingival flora of dogs and cats . It causes fulminant sepsis with disseminated intravascular coagulation DIC . Treatment Treatment is via antibiotics with the possible aid of activated protein C or plasmapheresis in severe cases. Following animal bites, co amoxiclav is often given to asplenic individuals to prevent disseminated infection but in patients who are allergic to penicillins, the combination of doxycycline and metronidazole to cover anaerobes anaerobic organisms may be used instead. In patients with sepsis, treatment with imipenem , clindamycin , or a penicillin &beta lactamase inhibitor combination e.g., co amoxiclav or piperacillin tazobactam should be used. ref cite journal title Antimicrobial treatment of Capnocytophaga infections author Jolivet Gougeon A, Sixou J, Tamanai Shacoori Z, Bonnaure Mallet M journal Int J Antimicrob Agents year 2007 volume 29 issue 4 pages 367 373 doi 10.1016 j.ijantimicag.2006.10.005 pmid 17250994 ref Doxycycline is active in vitro ref cite journal author Chraibi DI, Girond S, Michel G title Evaluation of the activity of four antimicrobial agents using an in vitro rapid micromethod against oral streptococci and various bacterial strains implicated in periodontitis journal J Periodontal Res year 1990 volume 25 issue 4 pages 201&ndash 6 pmid 2142728 doi 10.1111 j.1600 0765.1990.tb00905.x ref ref cite journal author Heimdahl A, Nord CE title Antimicrobial agents in the treatment of periodontal diseases special aspects on tetracycline and doxycycline journal Scand J ... more details
granulomatous disease . Asplenia , where there is no function of the spleen Complement deficiency ... species Asplenia Spleen Splenectomy Trauma medical Trauma Sickle cell anemia Polysaccharide encapsulated ... more details
Asplenia absence of normal spleen function or hyposplenism Anemia or hemorrhage Over medication ... , such as thrombocytosis due to congenital asplenia . ref cite pmid 11064471 http www.haematologica.org ... more details
Unreferenced date January 2009 A medical identification tag is a small emblem or tag worn on a bracelet, neck chain, or on the clothing bearing a message that the wearer has an important medical condition that might require immediate attention. The intention is to alert a paramedic, physician, emergency department personnel or other first responders of the condition even if the wearer is not conscious enough or old enough to explain. Some people prefer to carry a wallet card with the same information. A new type of medic identification alert is the USB medical alert tag. This is essentially a USB flash drive that contains an individual s emergency information. Because of the memory on the flash drive these USB medical alert tags are capable of carrying much more information than the conventional medical ID bracelet. Information such as medications, existing conditions, doctors and emergency contacts can all be stored on the USB tags. Emergency personnel can instantly access the information with any available computer, if they have access to a computer with a USB port and have the software to read the data, and their policies allow inserting USB drives of unknown origin into their computer systems. http www.diariodeburgos.es noticia.cfm Ribera 20080603 arandino reclama patente sistema guardar datos medicos 4B422DD3 1A64 968D 59498EECD6437B6B MemoHisT MHT http ecodiario.eleconomista.es salud noticias 579808 06 08 Un joven reclama la patente de un sistema que almacena datos medicos y que comercializa una empresa americana.html MemoHisT MHT http www.espatentes.com pdf 1058894 u.pdf MemoHisT MHT Conditions for use Typical conditions warranting such a tag are Asplenia Autism Alzheimer s Disease Rare blood type Hemophelia Von Willebrand Disease Advance Medical Directives Do Not Revive order, POLST, Durable Power of Attorney, Living Will Drug allergies Epilepsy Any seizure disorder Diabetes Type 1 Diabetes Type 1 and Type 2 Diabetes 2 Anaphylactic Allergies food, drug, inse ... more details
Taxobox name Asiatic tailed caecilians image Caecilian wynaad1.jpg image width 240px image caption Ichthyophis sp. from the Western Ghats regnum Animal ia phylum Chordate Chordata classis Amphibia ordo Gymnophiona familia Ichthyophiidae familia authority Edward Harrison Taylor Taylor , 1968 subdivision ranks Genera subdivision Caudacaecilia br Ichthyophis br Uraeotyphlus Image Caecilian wynaad2.jpg The vent is an important taxonomic feature for Ichthyophis identification thumb Ichthyophiidae is the family of Asiatic tailed caecilians or fish caecilians . They are found in south east Asia. They are primitive caecilian s, lacking many of the derived characters found in the other families. For example, the mouth is not recessed underneath the head, they possess tails, and have numerous scales on their body. However, they have two sets of muscles for closing the jaw, a feature unique to caecilians, but absent in the related family Rhinatrematidae . ref name EoR cite book editor Cogger, H.G. & Zweifel, R.G. author Nussbaum, Ronald A. year 1998 title Encyclopedia of Reptiles and Amphibians publisher Academic Press location San Diego isbn 0 12 178560 2 page 55 ref They lay their eggs in cavities in moist soil, where they hatch into larvae that seek out streams or underground seepages, before metamorphosing into adults. There is some evidence that the female may protect the eggs until they hatch. ref name EoR Taxonomy Family Ichthyophiidae Genus Caudacaecilia Caudacaecilia asplenia Broad striped Caecilian Caudacaecilia larutensis Larut Hills Caecilian Caudacaecilia nigroflava Kuala Lumpur Caecilian Caudacaecilia paucidentula Kapahiang Caecilian Caudacaecilia weberi Malatgan River Caecilian Genus Ichthyophis Ichthyophis acuminatus Elongate headed Caecilian Ichthyophis alfredii Ichthyophis atricollaris Long Bloee Caecilian Ichthyophis bannanicus Banna Caecilian Ichthyophis beddomei Yellow striped Caecilian Ichthyophis bernisi Indonesian Caecilian Ichthyophis biangularis Angul ... more details
e.g. chemotherapy or radio therapy, long term steroid use, and problems with the spleen asplenia ... Special risk group Children at special risk e.g. sickle cell disease and asplenia require as full ... more details
of pneumococci. In particular, the absence of a functional spleen , through congenital asplenia , splenectomy ... post splenectomy infection and prevention measures are indicated see asplenia . People whose immune ... more details
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