No footnotes date March 2012 STUMP stands for stromal tumor of undetermined malignant potential . They are atypical smooth muscle tumors with low mitotic activity . the Bell criteria were developed to help categorize them by the degree of cellular atypia atypia , the mitotic figures , and necrosis . Bell Criteria Atypia none minimal smooth Cell nucleus nuclei , smooth contours, minimal variation in nuclear size, shape, and evenly distributed chromatin moderate many large, plump, irregular nuclei, 1 2 mitotic figures severe obvious pleomorphism, enlarged bizarre nuclei with dense chromatin, giant cells , often multinucleated , enlarged, atypical nucleoli Mitotic figures Evaluation of the mitotic figures in a STUMP requires evaluation of 3 specific criteria Hairy extensions of chromatin must be present, extending from a central clot like dense mass of chromosomes . Hairy extensions from an empty center favor a non mitosis. Count 4 sets of 10 fields in the area of highest mitotic activity and use the highest count No nuclear membrane Rule out lymphocytes , mast cells , stripped nuclei , degenerated cells, and precipitate d hematoxylin . Necrosis coagulative necrosis Coagulative tumor cell necrosis is common in clinically malignant smooth muscle cell tumors. It consists of an abrupt transition between necrotic cells and preserved cells. Ghost nuclei from necrotic cells are often see, but inflammatory cells are uncommon. Hyalinizing necrosis is more common in leiomyomas. It consists ... to extrauterine tumors No or mild atypia, no tumor cell necrosis leiomyoma. If 5 or more mitotic figures are present in 10 high powered fields but the behavior still appears benign, may append with significant mitotic activity . Moderate to severe atypia without tumor cell necrosis atypical leiomyoma ... field Moderate to severe atypia and tumor cell necrosis leiomyosarcoma mitotic figures don t matter ... A title Uterine smooth muscle tumor of uncertain malignant potential a retrospective analysis ... more details
tumors in rat s are benign fibroadenomas, which are also the most common tumor in the rat. ref ...For mammary tumors in humans breast cancer A mammary tumor is a tumor originating in the mammary gland ... tumor type, malignant malignancy , and treatment options. The prevalence in dogs is about three ... 2007 03 21 ref In dogs, mammary tumors are the second most common tumor after skin tumors over all and the most common tumor in female dogs ref cite journal author Benjamin S, Lee A, Saunders W title ... 2007 03 21 ref Image Mammary tumor.JPG thumb Mammary tumor in a dog Mammary tumors in dogs File Lexhe magnant m tetes lon.jpg thumb Female dog with a 9 month old mammary tumor. Note the deep emaciation ... 7216 6795 3 ref although taking into account tumor behavior, one study has estimated true malignancy in mammary tumors to be 21 to 22 percent. ref name Schafer Adenoma s and fibroadenoma s make up the benign ... malignant type of canine mammary tumor. ref cite web last Nieto first Ana coauthors ... with invasive adenocarcinomas have an average survival time of one year. ref name Morrison 1998 Tumor ... year 2005 pmid 16313041 doi 10.2460 javma.2005.227.1625 ref Tumor type is also important. Sarcomas and carcinosarcomas .... ref name Ettinger 1995 Metastasis for any malignant mammary tumor is usually to the regional ... of this canine tumor has potential to complement and refine the current diagnostic and therapeutic approach to this tumor type. ref name Klopfleisch cite journal author Klopfleisch ... and location of the tumor is enough to identify it as a mammary tumor. Biopsy will give type and invasiveness of the tumor. In addition, newer studies showed that certain gene expression patterns are associated ... malignant from benign canine mammary tumors. journal Veterinary Pathology. volume 47 issue 3 pages ... of disease outcome when spaying was performed after the tumor had developed. Chemotherapy is rarely ... adenocarcinoma tumor size as a prognostic indicator journal Can Vet J volume 43 issue 1 pages 33 7 ... more details
Tumor promotion is a process in which existing tumors are stimulated to grow. It is the second phase in tumor development. Tumor promoters are not able to cause tumors to form. See also Tumor initiation Tumor progression External links http www.cancer.gov Templates db alpha.aspx?CdrID 390316 Tumor promotion entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Carcinogenesis Oncology stub ... more details
A primary tumor is a tumor growing at the anatomical site where tumor progression began and proceeded to yield a cancerous mass. References Weinberg, Robert. The Biology of Cancer, 2007. Category Types of neoplasia disease stub de Prim rtumor ... more details
A stromal tumor is a tumor that arises in the supporting connective tissue of an organ. External links http www.cancer.gov Templates db alpha.aspx?CdrID 44929 Stromal tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Types of neoplasia Oncology stub ... more details
A papillary tumor is a tumor shaped like a small mushroom , with its stem attached to the epithelial layer inner lining of an organ. External links http www.cancer.gov Templates db alpha.aspx?CdrID 46240 Papillary tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Types of neoplasia oncology stub ... more details
Glial tumor is a general term for numerous tumors of the central nervous system , including astrocytomas , ependymal tumor s, glioblastoma multiforme , and primitive neuroectodermal tumor s. External links http www.cancer.gov Templates db alpha.aspx?CdrID 45697 Glial tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Nervous system neoplasia oncology stub ... more details
Tumor antigen is an antigen ic substance produced in tumor Cell biology cells , i.e., it triggers an immune response in the Host biology host . Tumor antigens are useful in identifying tumor cells and are potential candidates for use in cancer therapy . Mechanism of tumor antigenesis Normal protein s in the body ... of tumor antigens Initially they were broadly classified into two categories based on their pattern of expression Tumor Specific Antigens TSA , which are present only on tumor cells and not on any other cell and Tumor Associated Antigens TAA , which are present on some tumor cells and also some normal cells. This classification, however,is imperfect because many antigens thought to be tumor specific turned out to be expressed on some normal cells as well. The modern classification of tumor ... needed date June 2010 Products of Mutated Oncogenes and Tumor Suppressor Genes Products of Other Mutated Genes Overexpressed or Aberrantly Expressed Cellular Proteins Tumor Antigens Produced ... Specific Differentiation Antigens Types Any protein produced in a tumor cell that has an abnormal structure due to mutation can act as a tumor antigen. Such abnormal proteins are produced due to mutation of the concerned gene . Mutation of protooncogene s and tumor suppressor s which lead to abnormal protein production are the cause of the tumor and thus such abnormal proteins are called tumor specific antigens . Examples of tumor specific antigens include the abnormal products of ras and p53 genes. In contrast, mutation of other genes unrelated to the tumor formation may lead to synthesis of abnormal proteins which are called tumor associated antigens . Proteins that are normally produced in very low quantities but whose production is dramatically increased in tumor cells, trigger an immune ... in melanoma cells. Oncofetal antigen s are another important class of tumor antigens. Examples are alphafetoprotein ... s may also have an abnormal structure in tumor cells and could thus be targets of the immune system ... more details
unreferenced date October 2011 Tumor progression is the third and last phase in tumor development. This phase is characterised by increased growth speed and invasiveness of the tumor cells. As a result of the progression, phenotypical changes occur. Together with the progression, more and more aneuploidy occurs. This leads to expression in cell and nuclear polymorphism. See also Tumor initiation Tumor promotion External links http www.cancer.gov Templates db alpha.aspx?CdrID 390316 Tumor progression entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Carcinogenesis Oncology stub ... more details
Infobox Disease Name Neuroectodermal tumor Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D018358 A neuroectodermal tumor is a tumor of the central nervous system central or peripheral nervous system . See also Neuroendocrine tumors Neuroectoderm Primitive neuroectodermal tumor PNET Medulloblastoma External links http www.cancer.gov Templates db alpha.aspx?CdrID 45952 Neuroectodermal tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Central nervous system tumors Category Anatomical pathology Category Nervous system neoplasia oncology stub fr Tumeur d origine neuroectodermique ... more details
Orphan date February 2009 A functioning tumor is a tumor that is found in endocrine tissue and makes hormones chemicals that travel in the bloodstream and control the actions of other cells or organs . External links http www.cancer.gov Templates db alpha.aspx?CdrID 458094 Functioning tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Types of neoplasia oncology stub ... more details
Micrograph of a neuroendocrine tumor. H&E stain . DiseasesDB ICD10 ICD9 ICD9 209 ICDO M8013 3 ... s. Many are benign , while some are malignant . They most commonly occur in the intestine, but are also ... with benign and those with uncertain behavior well differentiated low grade neuroendocrine carcinomas ... carcinoid goblet cell cancer , a rare gastrointestinal tract tumor . ref name vanEeden2007 cite doi 10.1111 j.1365 2559.2007.02883.x ref Placing a given tumor into one of categories depends on well defined ... associated protein 2 a new sensitive and specific marker for pulmonary carcinoid tumor and small ... of neuroendocrine tumors there are many different tumor types ref cite pmid 15053292 ref this outline ... or cancers at these locations. Pituitary neuroendocrine tumor of the anterior pituitary Thyroid ... pmid 21160597 ref including well differentiated NETs benign well differentiated NETs uncertain malignant ... neuroblastoma Breast ref cite pmid 11890336 ref Genitourinary tract urinary tract carcinoid tumor and neuroendocrine ... 7511278 ref ovary neuroendocrine tumor of the cervix ref name Soga2001Cerv cite pmid 11718210 ref testes ... stage A TNM staging system TNM scheme has been proposed for NETs by the European Neuroendocrine Tumor ... thumb right 200px Small intestine Small intestinal neuroendocrine tumor at bottom third of image, showing ... there can be anaplasia , mitosis mitotic activity, and necrosis . Some neuroendocrine tumor cells ... Tumor. http emedicine.medscape.com article 986050 overview ref These tumors can metastasize ... url In 800 autopsy cases, ... incidence of tumor was 10 6 60 in individuals having histological ... hormones. ref name Pommier 10 ref name HC Health Communities. Carcinoid Tumor Overview. http www.healthcommunities.com ... cause Cushing s syndrome . Occasionally, haemorrhage or the effects of tumor bulk are the presenting ... products ref name Pommier with an intense desmoplastic reaction at the tumor site, or of the mesentery ... tumors PETs or PNETs not to be confused with the Primitive neuroectodermal tumor primitive neuroectodermal ... more details
An ependymal tumor is a type of brain tumor that begins in cells lining the spinal cord central canal fluid filled space down the center or the Ventricular system ventricles fluid filled spaces of the brain . Ependymal tumors may also form in the choroid plexus tissue in the ventricles that makes cerebrospinal fluid . Also called ependymoma . External links http www.cancer.gov Templates db alpha.aspx?CdrID 45679 Ependymal tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Central nervous system tumors Category Brain tumor oncology stub ... more details
A Tumor Bank , as used in this article, is a term commonly used to describe a service that collects, stores and distributes fresh human tumor tissue for the purposes of biomedical research, primarily cancer research. A Tumor Bank is sometimes also referred to as a Tissue Bank , since normal tissues for research are also often collected. However, this function is distinct from a Tissue bank Tissue Bank which collects and harvests human cadaver tissue for medical research and education, and banks which store Biomedical tissue for organ transplantation. Cancer Samples Most tumor banks collect their tumor samples from discarded tissues not needed for pathologic diagnosis, after patients undergo surgery to remove the tumor. The tissue is often snap frozen in liquid nitrogen but may also be preserved in special fixative such as RNAlater which preserves RNA , or formalin which preserved tissue architecture. Many NCI designated Cancer Center Cancer Centers in the U.S. have a Tumor Bank to supply biomedical scientists with actual patient samples of cancer and associated adjacent normal tissue. This process is currently a high priority to support more Translational Research . See also Cooperative Human Tissue Network CHTN References cite journal author Hidalgo DO, Entrena NR title Tumor Banks for genomic and proteomic research journal Clinical and Translational Oncology volume 6 pages 381 390 year 2004 url http www.springerlink.com content x764rw76q2268446 cite journal author Isabelle M, Teodorovic I, Morente MM, et al. title TuBaFrost 5 multifunctional central database application for a European tumor bank journal Eur. J. Cancer volume 42 issue 18 pages 3103 9 year 2006 month December pmid 17029787 doi 10.1016 j.ejca.2006.04.032 External links http www.umassmed.edu cancercenter tissuebank index.aspx UMass Cancer Center Tumor Bank http www.cancerdiagnosis.nci.nih.gov specimens National Cancer Institute Human specimens for research Category Medical research ... more details
A Mixed tumor is a tumor that derives from multiple tissue types. ref http medical dictionary.thefreedictionary.com mixed tumor ref For example, a Chondroid syringoma is a cutaneous condition characterized histology histologically by nests of cuboidal or polygonal epithelial Cell biology cells in the dermis . ref name Andrews cite book author James, William D. Berger, Timothy G. et al. title Andrews Diseases of the Skin clinical Dermatology publisher Saunders Elsevier location year 2006 pages isbn 0 7216 2921 0 oclc doi accessdate ref rp 667 and it s of two types 1 derived from a single germ cell layer that differentiates into more than one cell type 2 derived from more than one germ cell layer totipotent cells See also Malignant mixed tumor Cylindroma Complex and mixed tumor List of cutaneous conditions References reflist Epidermal growth stub Category Epidermal nevi, neoplasms, cysts ... more details
Tumor hypoxia is the situation where tumor cell biology cells have been deprived of oxygen . As a tumor grows, it rapidly outgrows its blood supply, leaving portions of the tumor with regions where the oxygen concentration is significantly lower than in healthy tissues. Hypoxic tumor cells are usually resistant to radiotherapy and chemotherapy , ref W. A. Denny, Prodrug strategies in cancer therapy, Eur. J. Med. Chem., 2001, 36, 577 595 ref but they can be made more susceptible to treatment by increasing the amount of oxygen in them. Bioreductive prodrugs also play a significant part in dealing with these kinds of cells they can kill the oxygen deficient tumor cells selectively as hypoxic cytotoxins . The study of tumors in such conditions was pioneered by Louis Harold Gray Dr L. H. Gray . Tumor hypoxia can also be a result of the high degree of cell proliferation undergone in tumor tissue which causes a higher cell density and thus taxes the local oxygen supply. There are several companies working to address tumor hypoxia Novacea, Inc., Proacta Inc. and Threshold Pharmaceuticals, Inc. These companies are developing the following drug candidates AQ4N Novacea , PR 104 Proacta and TH 302 Threshold Pharmaceuticals . These drug candidates target levels of hypoxia that are common in tumors but are rare in normal tissues. The hypoxic zones of tumors generally evade traditional chemotherapeutic agents and ultimately contribute to relapse. In the literature, hypoxia has been demonstrated ... response. ref Association between tumor hypoxia and malignant progression in advanced cancer ... . ref Exploiting tumor hypoxia in cancer treatment J.M. Brown and W.R. Wilson Nat.Rev.Canc.4,437, 2004. ref ref Hypoxia targeting the tumor R.G. Boyle and S. Travess Anticancer Agents Med. Chem. 64 281 ... as a chemo and radio sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia ..., Charles H. Graham Cancer Metastatis Review 2007 26 319 331 DEFAULTSORT Tumor Hypoxia Category Oncology ... more details
The term tumor metabolome describes the characteristic metabolic phenotype of tumor cells. Comparison of the metabolic characteristics of different tumor cell lines and tumors revealed that during tumorigenesis, the same alterations always occur in distinct metabolic parameters regardless of the basic metabolism of the tissues from which the tumor developed, such as brain or liver and regardless of the molecular mechanism by which tumorigenesis was induced. The characteristic attributes of the tumor metabolome are high glycolysis glycolytic enzyme activities the expression of the pyruvate kinase isoenzyme type M2, which is mainly in its dimeric form Tumor M2 PK increased channeling of glucose carbons into synthetic processes, such as nucleic acid , amino acid and phospholipid synthesis a high rate of pyrimidine and purine de novo synthesis a low ATP GTP CTP UTP ratio low AMP levels high glutaminolysis glutaminolytic capacities release of immunosuppressive substances dependency on methionine References cite journal last Mazurek first S. coauthors Grimm H. Boschek CB Vaupel P Eigenbrodt E title Pyruvate kinase type M2 a crossroad in the tumor metabolome journal The British Journal of Nutrition month January year 2002 volume 87 issue S1 pages S23 S29 pmid 11895152 doi 10.1079 BJN2001455 cite journal last Mazurek first S. coauthors Eigenbrodt E. title The tumor metabolome journal Anticancer Research month March April year 2003 volume 23 pages 1149 1154 pmid 12820363 issue 2A External links http www.metabolic database.com metabolic database Category Metabolism Category Carcinogenesis oncology stub ... more details
A pelvic tumor is any one of numerous tumor s that occur in the pelvis . Within the pelvis, these tumors may involve specific organs, or occupy intra organ spaces. Tumors of the presacral space and sacral space are most prevalent in children. Tumors occupying specific organs have a more complex natural history. Tumors occupying specific organs Sacrococcygeal teratoma Bladder cancer Anal cancer Ovarian cancer Testicular cancer Tumors occupying intra organ spaces Presacral space Teratoma Sacral space in approximate order of prevalence Teratoma Lipoma Ganglioneuroma Myxopapillary ependymoma Primitive neuroectodermal tumor Aneurysmal bone cyst Ewing s sarcoma Metastasis Metastases from brain stem tumors medulloblastoma , ependymoma , high grade astrocytoma Complications Urinary incontinence Fecal incontinence disease stub tumors Category Types of neoplasia ... more details
Infobox Disease Name Wilms& 39 tumor Image Wilms tumor.jpg Caption Cut section showing two halves of a nephroblastoma ... of tumor into the renal pelvis, resembling botryoid rhabdomyosarcoma. DiseasesDB 8896 ICD10 ICD10 ... med eMedicineTopic 3093 eMedicine mult eMedicine2 ped 2440 MeshID D009396 Image Wilms Tumor CTScan.OGG thumb right thumbtime 3 Computed tomography CT Scan of 11 cm Wilms tumor of right kidney in 13 month old patient. Wilms tumor or nephroblastoma is cancer of the kidney s that typically occurs ... , referring to Dr. Max Wilms , the German surgeon 1867&ndash 1918 who first described this kind of tumor .... In cases of metastasis it is usually to the lung. A rupture of Wilms tumor puts the patient at risk of hemorrhage and peritoneal dissemination of the tumor. In such cases, surgical intervention by a surgeon who is experienced in the removal of such a fragile tumor is imperative. Pathologically, a triphasic nephroblastoma comprises three elements blastema mesenchyme epithelium Wilms tumor is a malignant tumor containing metanephric blastema , stromal and epithelial derivatives. Characteristic ... may include striated muscle , cartilage , bone , fat tissue, fibrous tissue. The tumor is compressing ... Diagnosis The first sign is normally a painless abdominal tumor that can be easily felt by the doctor. An Ultrasound, Computed Tomography, or MRI are done first. Once a kidney tumor is found, a surgical biopsy is done. A sample of tissue from the tumor is sent to a pathologist, who looks at it under a microscope to check for signs of cancer. Prognosis Tumor specific loss of heterozygosity LOH for chromosomes 1p and 16q identifies a subset of Wilms tumor patients who have a significantly increased ... for chromosomes 1p and 16q is an adverse prognostic factor in favorable histology Wilms tumor a report from the National Wilms Tumor Study Group journal Journal of Clinical Oncology J Clin Oncol year ... virtual karyotyping of tumor cells fresh or paraffin embedded . The overall prognosis with surgical ... more details
A tumor marker is a substance found in the blood , urine , or Biological tissue body tissues that can be elevated in cancer , among other tissue types. There are many different tumor markers, each indicative .... An elevated level of a tumor marker can indicate cancer however, there can also be other causes of the elevation. Tumor markers can be produced directly by the tumor or by non tumor cells as a response to the presence of a tumor. Most tumor markers are tumor antigen s, but not all tumor antigens can be used as tumor markers. Uses Uses of tumor markers can broadly be classified as follows ... sinus tumor . Diagnosis of specific tumor types, particularly in certain brain tumor s and other ... Z last3 Rayman first3 G pmc 1124444 ref Techniques Tumor markers can be detected by immunohistochemistry . If repeated measurements of tumor marker are needed, some clinical testing laboratories ... unless special calculations are performed. Interlaboratory proficiency testing for tumor marker ... genome.gov ref Examples class wikitable Tumor marker Associated tumor types Alpha fetoprotein AFP germ cell tumor , hepatocellular carcinoma ref name Territo2008 http books.google.com books?id pobC8zHbWzwC ... ref name Territo2008 CD34 hemangiopericytoma solitary fibrous tumor , pleomorphic lipoma , gastrointestinal stromal tumor , dermatofibrosarcoma protuberans ref name Territo2008 CD99 Ewing sarcoma , primitive neuroectodermal tumor , hemangiopericytoma solitary fibrous tumor , synovial sarcoma , lymphoma ... tumor , mastocytosis , seminoma ref name Territo2008 Chromogranin neuroendocrine tumor ref name ... disease , germ cell tumor , carcinoma ref name Territo2008 immunoglobulin lymphoma , leukemia ... PTPRC CD45 lymphoma , leukemia , histiocytic tumor ref name Territo2008 lymphocyte marker various ... adrenocortical carcinoma , gonadal tumor ref name Territo2008 Myo D1 rhabdomyosarcoma , small, round ... ref name Territo2008 neurofilament neuroendocrine tumor , small cell carcinoma of the lung ... more details
unreferenced date September 2008 Cartilage tumors form in Cartilage tissue. They can be either benign Chondroma or malignant chondrosarcoma . Frequently these tumors appear in bone , and not in pre existing cartilage tissue. In some cases tumors that formed in other tissues may produce a cartilage like matrix, an example of this is the pleomorphic adenoma of the sexual reproduction salivary glands . Osseous and chondromatous tumors Category Osseous and chondromatous neoplasia oncology stub ... more details
File Koenen.gif thumb Koenen tumor in patient with tuberous sclerosis complex. Koenen s tumor also known as Koenen s periungual fibroma ref name Fitz2 and Periungual fibroma ref name Bolognia cite book author Rapini, Ronald P. Bolognia, Jean L. Jorizzo, Joseph L. title Dermatology 2 Volume Set publisher Mosby location St. Louis year 2007 pages isbn 1 4160 2999 0 oclc doi accessdate ref is a cutaneous condition that results in fifty percent of tuberous sclerosis cases. ref name Fitz2 Freedberg, et. al. 2003 . Fitzpatrick s Dermatology in General Medicine . 6th ed. . McGraw Hill. ISBN 0071380760. ref rp 668 It can be subungual too. See also List of cutaneous conditions Nail anatomy Nail anatomy References reflist skin appendage stub Category Conditions of the skin appendages de Koenen Tumor pl Guzki Koenena ... more details
Infobox Disease Name Pancoast tumor Image Pancoast Tumor 1.jpg Caption Chest radiograph showing a Pancoast tumor labeled as P, non small cell lung carcinoma, right lung , from a 47 year old female smoker. DiseasesDB 31266 ICD10 ICD10 C 34 1 c 30 ICD9 ICD9 162.3 ICDO OMIM MedlinePlus eMedicineSubj med eMedicineTopic 3418 MeshID D010178 A Pancoast tumor , also called a pulmonary sulcus tumor or superior sulcus tumor , is a lung cancer tumor of the lung pulmonary apex. It is a type of lung cancer defined primarily by its location situated at the top end of either the right or left lung . It typically spreads to nearby tissues such as the ribs and vertebrae . Most Pancoast tumors are non small cell cancers. The growing tumor can cause compression of a brachiocephalic vein , subclavian artery , phrenic nerve , recurrent laryngeal nerve , vagus nerve , or, characteristically, compression of a sympathetic nervous system sympathetic ganglion resulting in a range of symptoms known as Horner s syndrome . Pancoast tumors are named for Henry Pancoast , a US radiologist , who described them in 1924 and 1932. ref WhoNamedIt synd 2953 ref Symptoms Aside from cancer general symptoms such as malaise ... tumor can give rise to both Pancoast syndrome and Horner s syndrome. When the brachial plexus ... for radical resection of Pancoast tumors ref gallery Image Pancoast Tumor 2.jpg CT scan showing a Pancoast tumor labeled as P, non small cell lung carcinoma, right lung , from smoker woman of 47 years old. gallery References reflist External links eMedicine radio 515 Pancoast Tumor http meded.ucsd.edu isp 1994 im quiz pancoast.htm Pancoast Tumor UCSD Xray http www.cancer.gov Templates db alpha.aspx?CdrID 44446 Pulmonary sulcus tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Respiratory tract neoplasia Category Lung cancer ca Tumor de Pancoast de Pancoast Tumor es ... pl Guz Pancoasta pt Tumor de Pancoast ru ... more details
Orphan date February 2009 Unreferenced date January 2007 Vestibular tumor s are growths that tend to develop underneath the serous tissue of the sublinguinal region. They may be found anywhere between the chin and the larynx or voicebox and are not more inclined to one side of the body than the other. They are predominantly present in adolescent females though they are not directly related to any hygienal issues. While surgery is the most often cure, deaths rarely occur due to the existence of vestibular tumors. History The first reported case of a vestibular tumor was in 1898 in Lancaster, Pennsylvania . Though there have been stories of growths of the like of vestibular tumors, this was the first medically reported case. At the time, surgery was too dangerous, so Emilia Walfen was forced to live with the tumor, which eventually grew to the size of a Concord grape . Issues arising from the presence of vestibular tumors While they are not always life threatening, they do propose a major health impediment. First of all, they can grow to be quite noticeable and after reaching a large size, are often easily irritable. Secondly they can lead to difficulty swallowing due to the pressure on the tongue or pharynx . Surgery is most often the decision made by the patients and it is rather affordable though if not treated may lead to life long problems. Category Types of neoplasia ... more details