- ATP2A3
PBB geneid 489 Sarcoplasmic endoplasmic reticulum calcium ATPase 3 is an enzyme that in humans is encoded by the ATP2A3 gene . ref name pmid8809064 cite journal author Dode L, Wuytack F, Kools PF, Baba Aissa F, Raeymaekers L, Brike F, van de Ven WJ, Casteels R title cDNA cloning, expression and chromosomal localization of the human sarco endoplasmic reticulum Ca 2 ATPase 3 gene journal Biochem J volume 318 issue 2 pages 689 99 year 1996 month Nov pmid 8809064 pmc 1217674 doi ref ref name entrez cite web title Entrez Gene ATP2A3 ATPase, Ca transporting, ubiquitous url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 489 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text This gene encodes one of the SERCA Ca 2 ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of cells. SERCA3 expression was originally described as non muscular, but was recently observed in cardiomyocyte. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in 6 transcript variants encoding different isoforms named SERCA3a to SERCA3f. ref name entrez References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Wuytack F, Papp B, Verboomen H, et al. title A sarco endoplasmic reticulum Ca 2 ATPase 3 type Ca2 pump is expressed in platelets, in lymphoid cells, and in mast cells. journal J. Biol. Chem. volume 269 issue 2 pages 1410 6 year 1994 pmid 8288608 doi cite journal author Dode L, De Greef C, Mountian I, et al. title Structure of the human sarco endoplasmic reticulum Ca2 ATPase 3 gene. Promoter analysis and alternative splicing of the SERCA3 pre mRNA. journal J. Biol. Chem. ... more details
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