Infobox disease Name Carcinoid ICD10 ICD10 C 75 c 73 , ICD10 E 34 0 e 20 ICD9 ICD9 209.60 ICDO ICDO 8240 3 Image Multiple Carcinoid Tumors of the Small Bowel 2.jpg Caption Picture of a carcinoid tumor ... med eMedicineTopic 271 DiseasesDB 2040 MeshID D002276 Image Carcinoid cancer.jpg thumb 240px Primary site of a carcinoid cancer of gut Carcinoid also carcinoid tumor is a slow growing ref name pmid17576444 ... and management of carcinoid tumors. Part 1 The gastrointestinal tract. A statement from a Canadian National Carcinoid Expert Group journal Curr Oncol volume 13 issue 2 pages 67 76 year 2006 month April ..., the World Health Organization redefined carcinoid , but this new definition has not been accepted ... DetailedGuide gastrointestinal carcinoid tumors what is gastrointestinal carcinoid title ACS What Is a Gastrointestinal Carcinoid Tumor? format work accessdate ref This has led to some complexity in distinguishing between carcinoid and other neuroendocrine tumors in the literature. According ... parts of the body. blockquote Carcinoid tumors are those neuroendocrine tumors that look more ... Carcinoid tumors are apudomas that arise from the enterochromaffin cell s throughout the gut. Over two thirds of carcinoid tumors are found in the gastrointestinal tract . ref name pmid12569593 cite journal author Modlin IM, Lye KD, Kidd M title A 5 decade analysis of 13,715 carcinoid tumors journal ... of carcinoid NCI Dictionary of Cancer Terms cite web url http www.cancer.gov Templates db alpha.aspx?CdrID 44233 title Definition of carcinoid NCI Dictionary of Cancer Terms format work accessdate ref Other sites metastases Carcinoid metastasis can lead to carcinoid syndrome . This is due to the over ... sided cardiac heart valve disease valve disease . It is estimated that less than 10 of carcinoid patients will develop carcinoid syndrome. Carcinoid tumors are also found in the lungs. History ... author Kulke MH, Mayer RJ title Carcinoid tumors journal N. Engl. J. Med. volume 340 issue 11 ... more details
Infobox Disease Name PAGENAME Image Strumal carcinoid intermed mag.jpg Caption Micrograph of a strumal carcinoid. H&E stain . DiseasesDB 33030 ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj article eMedicineTopic 256937 MeshID D013330 The strumal carcinoid is a type of monodermal teratoma with histomorphology histomorphologic features of 1 the thyroid gland and 2 a neuroendocrine tumour carcinoid . ref name pmid18509188 Cite journal last1 Gorin first1 I. last2 Sastre Garau first2 X. title Strumal carcinoid tumor of the ovary. journal J Clin Oncol volume 26 issue 16 pages 2780 1 month Jun year 2008 doi 10.1200 JCO.2008.16.1620 PMID 18509188 ref ref Cite journal last1 Tamsen first1 A. last2 Mazur first2 MT. title Ovarian strumal carcinoid in association with multiple endocrine neoplasia, type IIA. journal Arch Pathol Lab Med volume 116 issue 2 pages 200 3 month Feb year 1992 doi PMID 1346363 ref See also Struma ovarii Teratoma References Reflist 1 oncology stub Category Germ cell neoplasia ... more details
Infobox disease Name Carcinoid syndrome ICD10 ICD10 E 34 0 e 20 ICD9 ICD9 259.2 ICDO ICDO 8240 3 8245 Image Serotonin 5 HT .svg Caption Serotonin OMIM MedlinePlus 000347 eMedicineSubj med eMedicineTopic 271 DiseasesDB 2040 MeshID D008303 Carcinoid syndrome refers to the array of symptom s that occur secondary to carcinoidcarcinoid tumors . ref DorlandsDict nine 000951091 carcinoid syndrome ref The syndrome includes Flushing physiology flushing and diarrhea , and, less frequently, heart failure and bronchoconstriction ... File Carcinoid syndrome presentation.svg thumb 250px Presentation of the carcinoid syndrome. ref Table ... 7 oclc doi 8th edition. ref The carcinoid syndrome occurs in approximately 10 of carcinoid tumors ref ... carcinoid tumors metastasize to the liver or they arise for example in the bronchus. The most important ... of the mesentery or hepatic metastases. Although the most common site of a carcinoid tumor is the appendix ... are required for the carcinoid syndrome to occur. This is because serotonin created by a GI carcinoid ... not need to occur in order for carcinoid syndrome to occur. Pathophysiology Carcinoid tumors produce ... , one of the most powerful vasodilators known. Other components of the carcinoid syndrome are diarrhea ..., the serotonin and kallikrein are inactivated in the liver manifestations of carcinoid syndrome ... failure cirrhosis . Carcinoid tumors arising in the bronchi may be associated with manifestations of carcinoid ... of 5 HIAA 5 hydroxyindoleacetic acid , the end product of serotonin metabolism. Patients with carcinoid ... CT, which evaluate for increased metabolism of glucose, may also aid in localizing the carcinoid lesion ... Carcinoid cancer.jpg thumb 240px Primary site of a carcinoid cancer of gut, secondaries are also visible on the mesentery Treatment For symptomatic relief of carcinoid syndrome octreotide a somatostatin ... syndrome Cassidy Scholte sydrome Flush syndrome References reflist 2 See also Carcinoid Neuroendocrine tumor Kulchitsky cells Apudoma Endocrine pathology DEFAULTSORT Carcinoid Syndrome Category ... more details
Use mdy dates date November 2011 The Caring for Carcinoid Foundation CFCF is a nonprofit corporation organized under the laws of Massachusetts in order to support carcinoid cancer research in the public ... title Governing Documents & 124 Caring for Carcinoid Foundation publisher Caringforcarcinoid.org ... doctors and scientists who are researching the causes of carcinoid ref cite web url http www.nlm.nih.gov medlineplus ency article 000347.htm title Carcinoid syndrome MedlinePlus Medical Encyclopedia ... web url http www.prnewswire.com news releases the caring for carcinoid foundation celebrates worldwide ... The Caring for Carcinoid Foundation Celebrates Worldwide Neuroendocrine Tumor Cancer Awareness Day ... to discovering a cure for carcinoid cancer . ref http www.health.gov nhic scripts Entry.cfm?HRCode ... . ref cite web url http www.bbb.org charity reviews national cancer caring for carcinoid foundation in cambridge ma 3457 title Charity Review of Caring for Carcinoid Foundation publisher Bbb.org date ... formerly Nancy O Hagan , who is herself a carcinoid patient. ref cite web url http www.caringforcarcinoid.org about cfcf founder nancy lindholm title Founder Nancy Lindholm & 124 Caring for Carcinoid ... Asked Questions & 124 Caring for Carcinoid Foundation publisher Caringforcarcinoid.org accessdate ... for carcinoid foundation.html ref From time to time the Foundation makes grants available jointly ... funding fellowships caring for carcinoid foundation aacr grants for carcinoid tumor and pancreatic ... grant provider. ref cite web url http www.medicalnewstoday.com articles 55021.php title Carcinoid ... Dollars Carcinoid Tumor Research Grant publisher Medicalnewstoday.com accessdate November 10, 2011 ... for Carcinoid Foundation http www.caringforcarcinoid.org cfcf story The CFCF Story http www.facebook.com CaringForCarcinoidFoundation The Caring for Carcinoid Foundation on Facebook http twitter.com CureCarcinoid The Caring for Carcinoid Foundation on Twitter Category Cancer organizations Category Medical ... more details
Infobox Disease Name PAGENAME Image Goblet cell carcinoid 2 high mag.jpg Caption Micrograph showing a goblet cell carcinoid. H&E stain . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID The goblet cell carcinoid , abbreviated GCC and also known as crypt cell carcinoma and neuroendocrine tumour with goblet cell differentiation , is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma . ref name pmid18042066 cite journal author van Eeden S, Offerhaus GJ, Hart AA, et al. title Goblet cell carcinoid of the appendix a specific type of carcinoma journal Histopathology volume 51 issue 6 pages 763 73 year 2007 month December pmid 18042066 doi 10.1111 j.1365 2559.2007.02883.x url ref Sign and symptoms GCCs may present as appendicitis . Diagnosis Image Goblet cell carcinoid very low mag.jpg thumb Micrograph of a goblet cell carcinoid. H&E stain . GCCs are diagnosed by pathology . They have a characteristic biphasic appearance which includes 1 goblet cell like cells, and 2 neuroendocrine type nuclear chromatin stippled chromatin . Prognosis GCCs have an aggressive course vis a vis other appendiceal neuroendocrine tumours. ref name pmid18042066 Treatment GCCs are treated with surgery. See also Neuroendocrine tumours References Reflist 1 Category Gastrointestinal cancer ... more details
Endocrine oncology refers to a medical speciality dealing with hormone producing tumors, i.e. a combination of endocrinology and oncology . Few centres are specializing in hormone producing tumors only, due to the relatively low Incidence epidemiology incidence . Most centres have gastroenterologists, oncologist or endocrinologists who deal with other diseases as well. One exception is the Uppsala Centre of Excellence in Neuroendocrine Tumors ref http www.endocrinetumors.org ref at Uppsala University Hospital in Sweden , where doctors treat only endocrine tumors. Endocrine tumors There are many different kinds of endocrine tumors, some of which are listed below Gastrointestinal ECLoma Midgut carcinoid Appendix carcinoid Hindgut carcinoid sometimes also referred to as Rectal carcinoid Pulmonary Typical bronchial carcinoid Atypical bronchial carcinoid Large cell neuroendocrine carcinoma Small cell lung cancer Endocrine pancreatic tumors Non functioning endocrine pancreatic tumors Insulinoma Gastrinoma Glucagonoma VIPoma Adrenals Adrenocortical carcinoma Pheochromocytoma Endocrine tumor syndromes Multiple Endocrine Neoplasia I, MEN1 Multiple Endocrine Neoplasia II, MEN2 von Hippel Lindau syndrome References Reflist Category Endocrine neoplasia Category Rare cancers ... more details
5 HIAA is a metabolite of serotonin, testing is most frequently performed for the diagnosis of carcinoid ... if the patient has malabsorption are strong evidence for carcinoid. Low levels of 5 HIAA in the cerebrospinal ... date March 2011 5 HIAA may be normal with nonmetastatic carcinoid tumor and may be normal even with the carcinoid syndrome, particularly in subjects without diarrhea, because some patients with the carcinoid ... the carcinoid syndrome with 5 HIAA elevation. Patients with renal disease may have falsely low 5 HIAA ... obstruction. Poor correlation exists between 5 HIAA level and the clinical severity of the carcinoid ... 5 HIAA, are produced in excess by most carcinoid tumors, especially those producing the carcinoid syndrome ... of urinary 5 HIAA is the best test for carcinoid, but scrupulous care must be taken that specimen collection and patient preparation have been correct. Carcinoid tumors may cause increased excretion ... carcinoid usually contain and release large quantities of serotonin. These amounts may not be fully ... cells bronchial, pancreatic, duodenal, or biliary carcinoid produce large amounts of serotonin ... rectal carcinoid rarely produce excess serotonin or 5 HIAA. Of 75 patients with carcinoid tumors, 75 ... Warner RR, Carcinoid Tumor, Volume 3, 1874 6. cite journal author Agranovich AL, Anderson GH, Manji M, Acker BD, Macdonald WC, Threlfall WJ title Carcinoid tumour of the gastrointestinal tract ... serotonin in the diagnosis of carcinoid tumors journal Clin. Chem. volume 32 issue 5 pages 840 4 year ... more details
Diagnostic infobox Name PAGENAME Image Octreoscan.jpg Caption 111In pentetreotide scintigraphy of the 41 year old man with ectopic Cushing syndrome caused by a neuroendocrine carcinoma of the mesentery. Radiotracer accumulation in the left thyroid in 10 2003 arrow . The mesenterial neuroendocrine tumor became clearly visible in 4 2005 arrow . ICD10 ICD9 ICD9proc 92.18 MeshID OPS301 OPS301 3 70c OtherCodes An octreotide scan or octreoscan is a type of scintigraphy used to find carcinoid and other types of tumors and to localize sarcoidosis. Octreotide , a drug similar to somatostatin , is radiolabeled with indium 111 , ref http www.medicinenet.com carcinoid syndrome page4.htm medicinenet.com Carcinoid Syndrome cont. By Dennis Lee and Jay Marks. Retrieved Mars 2011 ref and is injected into a vein and travels through the bloodstream . The radioactive octreotide attaches to tumor cells that have receptors for somatostatin. A radiation measuring device detects the radioactive octreotide, and makes pictures showing where the tumor cells are in the body. It is also called somatostatin receptor scintigraphy and SRS. References reflist External links http www.cancer.gov Templates db alpha.aspx?CdrID 390304 Octreotide scan entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Medical imaging Category 2d nuclear medical imaging oncology stub ... more details
HIAA may refer to Health Insurance Association of America Halifax International Airport Authority 5 Hydroxyindoleacetic acid 5 HIAA , a metabolite of serotonin used to diagnose carcinoid tumors. Disambiguation Short pages monitor This long comment was added to the page to prevent it being listed on Special Shortpages. It and the accompanying monitoring template were generated via Template Longcomment. Please do not remove the monitor template without removing the comment as well. ... more details
Infobox scientist name PAGENAME image Oberndorfer.JPG image size 120px caption PAGENAME birth date 24 June 1876 birth place Munich death date 1944 death place Istanbul residence citizenship nationality ethnicity field physician br pathologist work institutions alma mater doctoral advisor doctoral students known for carcinoid author abbrev bot author abbrev zoo influences influenced prizes religion footnotes signature Siegfried Oberndorfer 24 June 1876 in Munich 1944 in Istanbul was a German physician and pathologist . Oberndorfer studied medicine in Munich and Kiel and Ph.D in 1900 in Munich and habilitated in pathological anatomy in 1906 also in Munich. From 1910 he was the head of Pathology Department of the hospital in Munich Schwabing. In 1907 he introduced the medical term carcinoid German Karzinoide that is still in use until the present day ref cite journal quotes yes last Soga first Jun authorlink year 2009 month Nov. title The life of S. Oberndorfer the proposer of the term carcinoid the outcome of a seed in the past 100 years journal Nippon Rinsho volume 67 issue 11 pages 2201 6 publisher location Japan issn 0047 1852 pmid 19899541 bibcode oclc id url language jpn format accessdate laysummary laysource laydate quote ref . References references Publications Karzinoide Tumoren des D nndarmes. Frankfurter Zeitschrift f r Pathologie, 1907, 1 426 429. Pathologisch anatomische Situsbilder der Bauchh hle. In Lehman s Medizinische Atlanten, Munich, 1922. Die Geschw lste des Darmes. In Handbuch der pathologischen Anatomie, Band 4,3, Berlin, 1929. Prostata, Hoden, Geschw lste. In Handbuch der pathologischen Anatomie, Band 6, Berlin, 1931. Further reading Irwin M. Modlin, Michael D. Shapiro, Mark Kidd Siegfried Oberndorfer Origins and perspectives of carcinoid tumors . Human pathology, Philadelphia, 2004, 35 12 1440 1451. M. L. Corman and A. Khoynezhad Siegfried Oberndorfer. In M.L. Corman Colon and Rectal Surgery. Philadelphia Lippincott Williams & Wilkins 2005 1091 ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD10 C 17 c 15 ICD9 ICD9 152 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D007414 Image Duodenal adenocarcinoma.png right thumb 220px Esophagogastroduodenoscopy Endoscopic image of adenocarcinoma of duodenum seen in the post bulbar duodenum. Image Multiple Carcinoid Tumors of the Small Bowel 2.jpg thumb 220px Picture of a carcinoid tumour that encroaches into lumen of the small bowel . Pathology specimen. The prominent folds are plicae circulares , a characteristic of small bowel . In oncology , small intestine cancer , also small bowel cancer and cancer of the small bowel , is a cancer of the small intestine . It is relatively rare compared to other Gastrointestinal cancer gastrointestinal malignancies such as gastric cancer stomach cancer and colorectal cancer . ref name terry Terry SM, Santora T. Benign Neoplasm of the Small Intestine. eMedicine.com. URL http www.emedicine.com med topic2652.htm http www.emedicine.com med topic2652.htm . Accessed on June 2, 2006. ref Small intestine cancer can be subdivided into duodenal cancer the first part of the small intestine and cancer of the jejunum and ileum the later two parts of the small intestine . Duodenal cancer has more in common with stomach cancer , while cancer of the jejunum and ileum have more in common with colorectal cancer . Several different subtypes of small intestine cancer exist. These include adenocarcinoma gastrointestinal stromal tumor lymphoma ileal carcinoid tumor Risk factors Risk factors for small intestine cancer include ref cite journal author Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C title Pathogenesis and risk factors of small bowel adenocarcinoma a colorectal cancer sibling? journal Am. J. Gastroenterol. volume 100 issue 3 pages 703 10 year 2005 month March pmid 15743371 doi 10.1111 j.1572 0241.2005.40605.x ref ref Chen AC, Neugut AI. Malignant Neoplasms of the Small Intestine. eMedicine.com. URL http www.e ... more details
Guidelines for the management of gastroenteropancreatic neuroendocrine including carcinoid tumours journal ... year 2003 pages 195 233 isbn 3 540 43462 3 oclc doi accessdate ref They were named carcinoid tumors ... NETs are sometimes incorrectly subsumed into the term carcinoid. Enterochromaffin cells, which give rise to carcinoid tumors, were identified in 1897 by Kulchitsky ref name Modlin and their secretion ... clinically recognized. Carcinoid heart disease was identified in 1952 ref name Modlin and carcinoid ... 100,000 ref name berg2011 cite doi 10.1007 s10555 011 9292 1 ref two thirds are carcinoid tumors and one ... carcinoid goblet cell cancer , a rare gastrointestinal tract tumor . ref name vanEeden2007 cite doi ... associated protein 2 a new sensitive and specific marker for pulmonary carcinoid tumor and small ... carcinoid tumors ref name Soga1999 cite pmid 10550713 ref ref name berg2008 BronchThymusESMO ... pulmonary carcinoid tumors typical carcinoid TC low grade atypical carcinoid AC intermediate ... neuroblastoma Breast ref cite pmid 11890336 ref Genitourinary tract urinary tract carcinoid tumor and neuroendocrine .... There may be associated atypical carcinoid syndrome, acromegaly, Cushing disease, other endocrine disorders, telangiectasia, or hypertrophy of the skin in the face and upper neck. ref Tebbi CK. Carcinoid ... There are two main types of NET within this category Carcinoid tumors Main Carcinoid about two thirds ... hormones. ref name Pommier 10 ref name HC Health Communities. Carcinoid Tumor Overview. http www.healthcommunities.com carcinoid malignancy carcinoid malignancy overview.shtml ref or less of carcinoids ... serotonin 5 HT or substance P , ref name Kvols Kvols LK. 2002. Carcinoid Tumors and the Carcinoid Syndrome What s New in the Therapeutic Pipeline. The Carcinoid Cancer Foundation Carcinoid Symposium 2002 http www.carcinoid.org content carcinoid tumors and carcinoid syndrome whats new therapeutic pipeline ref causing a constellation of symptoms called carcinoid syndrome Flushing physiology flushing ... more details
Infobox Disease Name PAGENAME Image Struma ovarii intermed mag.jpg Caption Micrograph of a struma ovarii. Characteristic thyroid follicle s are seen on the right, and ovary ovarian stroma of ovary stroma on the left. H&E stain . DiseasesDB 33030 ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj article eMedicineTopic 256937 MeshID D013330 A struma ovarii literally goitre of the ovary is a rare disease rare form of monodermal teratoma that contains mostly thyroid tissue , which lead to hyperthyroidism. ref name pmid19265502 cite journal author Kim D, Cho HC, Park JW, et al title Struma ovarii and peritoneal strumosis with thyrotoxicosis journal Thyroid volume 19 issue 3 pages 305 8 year 2009 month March pmid 19265502 doi 10.1089 thy.2008.0307 ref Despite its name, struma ovarii is not restricted to the ovary. The vast majority of struma ovarii are benign tumor s however, malignant tumor s of this type is found in a small percentage of cases. ref EMedicine article 256937 Struma Ovarii ref See also Teratoma Strumal carcinoid Additional images gallery Image Struma ovarii low mag.jpg Low mag. Image Struma ovarii high mag.jpg High mag. gallery References reflist oncology stub Germ cell tumors Endocrine gland neoplasia Female genital neoplasia Category Germ cell neoplasia de Struma ovarii ... more details
Infobox Anatomy Name PAGENAME Latin pars terminalis GraySubject GrayPage Image Mantle cell lymphoma low mag.jpg Caption Micrograph of terminal ileum with mantle cell lymphoma . H&E stain . Image2 Mantle cell lymphoma low mag cyclin D1.jpg Caption2 Micrograph of terminal ileum with mantle cell lymphoma . Cyclin D1 immunostain . Precursor System Artery Vein Nerve Lymph MeshName MeshNumber The terminal ileum is the most distal part of the small intestine . It connects to the cecum , the pouch between the small and the large intestine, via the ileocecal valve . Pathology of the terminal ileum It is importance in medicine as it can be affected in a number of diseases, ref Cite journal last1 Cuvelier first1 C. last2 Demetter first2 P. last3 Mielants first3 H. last4 Veys first4 EM. last5 De Vos M first5 . title Interpretation of ileal biopsies morphological features in normal and diseased mucosa. journal Histopathology volume 38 issue 1 pages 1 12 month Jan year 2001 doi 10.1046 j.1365 2559.2001.01070.x PMID 11135039 ref including Crohn s disease Tuberculosis Lymphoma Neuroendocrine tumours carcinoid Additional images gallery File Ileum, cecum and ascending colon.JPG Ileum Image Illu small intestine.jpg Small intestine Image Gray1045.png The cecal fossa. The ileum and cecum are drawn backward and upward. gallery References reflist 1 Category Digestive system medicine stub Digestive tract ... more details
Infobox Anatomy Name Enteroendocrine cells Latin endocrinocyti gastroenteropancreatici GraySubject GrayPage Image Digestive hormones.jpg Caption Actions of the major digestive hormones secreted by enteroendocrine cells Image2 Caption2 Precursor System Artery Vein Nerve Lymph MeshName Enteroendocrine cells MeshNumber Code TerminologiaHistologica 3 04 02.0.00024 BR TerminologiaHistologica 3 08 01.0.00003 Enteroendocrine cells are specialized endocrine cell biology cell s of the gastrointestinal tract . They produce hormone s such as serotonin ref UIUCHistologySubject 321 ref , somatostatin , motilin , cholecystokinin , gastric inhibitory peptide , neurotensin , vasoactive intestinal peptide , and enteroglucagon . Most enteroendocrine cells are found in the islets of Langerhans , but they are also found in other locations. For example, the G cell s which secrete gastrin are located primarily in the stomach . ref Medcyclopaedia iv 1 g G cell ref Enteroendocrine cells are also found in the duodenum . ref BUHistology 11604loa Endocrine System duodenum, enteroendocrine cells ref Enterochromaffin like cell and enterochromaffin cells are also considered enteroendocrine cells. ref MeshName Enteroendocrine cells ref Pathology Rare and slow growing carcinoid tumors develop from these cells. When a tumor arises it has the capacity to secrete large volumes of hormones. See also APUD cell References reflist Gastrointestinal physiology Human cell types derived primarily from endoderm Endocrine system anatomy Category Endocrine system Category Cells sl Enteroendokrina celica ... more details
String sign , or gastrointestinal string sign, is a medical term for a radiographic finding on an Upper GI series , in which the patient is given a radio opaque material, such as barium, to drink. X ray s are then taken of the patient s stomach and intestines. The gastrointestinal string sign represents a severe narrowing of loop of bowel, in which a thin stripe of contrast within the lumen looks like a string. It may be seen in Crohn s Disease , Pyloric stenosis Hypertrophic Pyloric Stenosis HPS , Carcinoid and Colon Cancer . In people with Crohn s Disease, the string sign is caused by incomplete filling of the intestinal lumen, which results from irritability and spasm associated with severe ulceration. In such cases, the string sign is most frequently seen at the terminal ileum. In infants with Hypertrophic Pyloric Stenosis HPS , the pylorus is narrowed and the radio opaque material will take on the appearance of a thin string as it passes through this narrowed channel. Often, there are several of these strings seen called the railroad track sign . The use of the Upper GI series for the diagnosis of HPS, which was the primary diagnostic tool for this condition in the 1980s and 1990s, has been largely replaced by the use of ultrasound , which is less invasive and can visualize the thickened pylorus, giving actual measurements of this thickening. References Nelson s Textbook of Pediatrics, Twelfth Edition. Richard Behrman, M.D. and Victor Vaughan, III, M.D. Editors, p. 904. Radiology 2007 242 632 633, 10.1148 radiol.2422041244 Category Gastroenterology ... more details
Infobox Anatomy Name Seminal colliculus Latin colliculus seminalis GraySubject 256 GrayPage 1234 Image Gray1153.png Caption Vesicul seminales and ampull of ductus deferentes, seen from the front. Image2 Gray1142.png Caption2 The male urethra laid open on its anterior upper surface. System MeshName MeshNumber DorlandsPre c 61 DorlandsSuf 12265795 The seminal colliculus Latin colliculus seminalis , or verumontanum , of the prostatic urethra is a landmark near the entrance of the seminal vesicle s. Verumontanum is translated from Latin to mean mountain ridge , a reference to the distinctive median elevation of urothelium that characterizes the landmark on magnified views. Embryo logically, it is derived from the uterovaginal primordium . The landmark is important in classification of several urethra l developmental disorders. The margins of seminal colliculus are the following the orifices of the prostatic utricle the slit like openings of the ejaculatory duct s. the openings of the prostatic ducts Posterior urethral valves The verumontanum is an important anatomic landmark for pathology in a congenital anomaly known as posterior urethral valve s, in which there is a developmental obstruction of the urethra in newborn male infants. ref cite web url http emedicine.medscape.com article 412226 title Posterior Urethral Valve. Emedicine, Radiology. accessdate July 18, 2010 date July 18, 2010 publisher eMedicine ref Urethral carcinoid tumors have been reported at the verumontanum. ref Maxwell Smith , M Scott Lucia , Priya N Werahera and Francisco G La Rosa Carcinoid tumor of the verumontanum colliculus seminalis of the prostatic urethra with a coexisting prostatic adenocarcinoma a case report Journal of Medical Case Reports 2010, 4 16 ref The structure tends to migrate Caudal anatomical term caudally , or downward, in hypospadia disorders and is then seen in the bulbous, or penile portion of the urethra. ref F Ikoma, H Shima. 1991. Caudal migration of the verumontanum. Jou ... more details
needed date May 2011 Diseases A cecal carcinoid tumor is a carcinoid tumor of the cecum. A appendiceal carcinoid tumor a carcinoid tumor of the appendix is sometimes found next to a cecal carcinoid. Citation ... more details
Jehudah Menachem Mendel Mendy Samstein July 25, 1938 January 24, 2007 was an United States American civil rights activist. Born in Manhattan , he majored in European history at Brandeis University Brandeis , and later earned a master s degree in the same subject from Cornell University Cornell . He was studying for a Ph.D. in history at the University of Chicago when he quit to join the civil rights movement in the South. He became a full time organizer for the Student Nonviolent Coordinating Committee or SNCC, pronounced snick . Stokely Carmichael , later chairman of SNCC, called Samstein one in a million . Later on, Samstein also organized protests against the Vietnam War . He had a variety of jobs, including working as a teacher, as a psychoanalyst, and running a summer camp. In 2000, he and other civil rights veterans protested the handling of the United States presidential election, 2000 Florida results presidential vote in Florida . Samstein was married to Nancy Cooper, a fellow civil rights activist. He died from carcinoid cancer at his home in New Lisbon, New York , aged 68. External links http www.nytimes.com 2007 01 25 obituaries 25samstein.html? r 1&oref slogin Obituary at New York Times Persondata Metadata see Wikipedia Persondata . NAME Samstein, Mendy ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH July 25, 1938 PLACE OF BIRTH DATE OF DEATH January 24, 2007 PLACE OF DEATH DEFAULTSORT Samstein, Mendy Category 1938 births Category 2007 deaths Category American civil rights activists Category Brandeis University alumni Category Cornell University alumni Category American Jews Category People from New York City Category Cancer deaths in New York ... more details
This is a list of cancer types , ordered alphabetically. CompactTOC8 f F j J q Q x X y Y z Z A Acute lymphoblastic leukemia Acute myeloid leukemia Adrenocortical carcinoma AIDS Major HIV associated malignancies AIDS related cancers AIDS related lymphoma Anal cancer Appendix cancer Astrocytoma , childhood cerebellar or Cerebrum cerebral B Basal cell carcinoma Bile duct cancer , extrahepatic Bladder cancer Bone cancer , Osteosarcoma Malignant fibrous histiocytoma Brainstem glioma Brain tumor Brain tumor, cerebellar astrocytoma Brain tumor, cerebral astrocytoma malignant glioma Brain tumor, ependymoma Brain tumor, medulloblastoma Brain tumor, supratentorial primitive neuroectodermal tumors Brain tumor, visual pathway and hypothalamic glioma Breast cancer Bronchial adenomas carcinoids Burkitt lymphoma C Carcinoid tumor , childhood Carcinoid tumor, gastrointestinal Carcinoma of unknown primary Primary central nervous system lymphoma Central nervous system lymphoma, primary Cerebellar astrocytoma , childhood Cerebral astrocytoma Malignant glioma , childhood Cervical cancer Cancer Child cancers Childhood cancers Chronic lymphocytic leukemia Chronic myelogenous leukemia Chronic myeloproliferative disorder s Colorectal cancer Colon Cancer Cutaneous T cell lymphoma D Desmoplastic small round cell tumor E Endometrial cancer Ependymoma Esophageal cancer Ewing s sarcoma in the Ewing family of tumors Extracranial germ cell tumor, Childhood Extragonadal Germ cell tumor Extrahepatic bile duct cancer Eye Cancer , Intraocular melanoma Eye Cancer, Retinoblastoma G Gallbladder cancer Gastric cancer Gastric Stomach cancer Gastrointestinal Carcinoid Tumor Gastrointestinal stromal tumor GIST Germ cell tumor extracranial, extragonadal, or ovarian Gestational trophoblastic tumor Glioma of the brain stem Glioma, Childhood Cerebral Astrocytoma Glioma, Childhood Visual Pathway and Hypothalamic Gastric carcinoid H Hairy cell leukemia Head and neck cancer Heart cancer Hepatocellular carcinoma He ... more details
Pulmonic regurgitation , also known as pulmonary regurgitation , is the backward flow of blood from the pulmonary artery , through the pulmonary valve , and into the right ventricle of the heart during diastole . While a small amount of pulmonic regurgitation may occur in healthy individuals, it is usually detectable only by an echocardiogram and is harmless. More pronounced regurgitation that is noticed through a routine physical examination is a medical sign of disease and warrants further investigation. Signs and symptoms Mild cases usually do not cause any symptoms. Because pulmonic regurgitation is the result of other factors in the body, any noticeable symptoms are ultimately caused by an underlying medical condition rather than the regurgitation itself. However, more severe regurgitation may contribute to right ventricular hypertrophy , and in later stages, Cor pulmonale right heart failure . A decrescendo murmur can sometimes be identified early in diastole, heard best over the left lower sternal border. Causes Pulmonary Hypertension Infective endocarditis Rheumatic heart disease Congenital absence of the pulmonary valve Carcinoid Syndrome Congestive abnormalities Tetralogy of Fallot, a malformation of the heart characterized by four co occurring defects 1 a ventricular septal defect, 2 a misplaced origin of the aorta causing it to override the septal defect, 3 narrowing of the pulmonary artery, and 4 enlargement of the right ventricle. Itrogenic post surgical repair for congenital heart disease Chest trauma Carcenoid heart disease tumor Prosthetic heart valve dysfunction Treatment Asymptomatic cases do not require treatment. Pulmonic regurgitation is generally treated by addressing the underlying condition. In certain cases, the pulmonary valve may be valve replacement surgically replaced . References Lange 2008 Current Medical Diagnosis and Treatment, 47th edition pp. 298 299 ISBN 978 8 07 149430 4 Xiushui, R., Saavedra, P., Cannistra, L. Pulmonic Reg ... more details
Image Small intestine neuroendocrine tumour high mag cropped.jpg thumb 300px right Neuroendocrine tumour of the small intestine with salt and pepper chromatin . H&E stain . In pathology , salt and pepper chromatin , also salt and pepper nuclei and stippled chromatin , refers to cell nucleus cell nuclei that demonstrate granular chromatin on light microscopy . ref cite journal author Chetty R, Asa SL title Pancreatic endocrine tumour with cytoplasmic keratin whorls. Is the term rhabdoid appropriate? journal J. Clin. Pathol. volume 57 issue 10 pages 1106 10 year 2004 month October pmid 15452172 pmc 1770450 doi 10.1136 jcp.2004.018309 url ref Salt and pepper chromatin is typically seen in endocrine tumours such as medullary thyroid carcinoma , neuroendocrine tumour s ref cite journal author Van Buren G, Rashid A, Yang AD, et al. title The development and characterization of a human midgut carcinoid cell line journal Clin. Cancer Res. volume 13 issue 16 pages 4704 12 year 2007 month August pmid 17699847 doi 10.1158 1078 0432.CCR 06 2723 url ref and pheochromocytoma . ref cite journal author Shidham VB, Galindo LM title Pheochromocytoma. Cytologic findings on intraoperative scrape smears in five cases journal Acta Cytol. volume 43 issue 2 pages 207 13 year 1999 pmid 10097711 doi url ref Additional images gallery Image Adrenal pheochromocytoma 2 histopathology.jpg A pheochromocytoma showing finely granular chromatin. H&E stain . Image Adrenal pheochromocytoma 3 histopathology.jpg A pheochromocytoma showing finely granular chromatin. H&E stain . Image Pheochromocytoma high mag.jpg Salt and pepper chromatin pheochromocytoma . H&E stain. gallery References reflist External links http www.nature.com modpathol journal v15 n5 fig tab 3880561f1.html Salt and pepper chromatin nature.com. http path.upmc.edu cpcases case1 surgpath.html Salt and pepper nucleus upmc.edu. Category Pathology ... more details
Infobox Disease Name PAGENAME Image Big Liver Tumor.JPG Caption left lobe liver tumor in 50 year old man operated in King Saud Medical Complex, Riyadh, Saudi Arabia DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D008113 Nofootnotes article date September 2009 Liver tumors or hepatic tumors are tumors or growths on or in the liver medical terms pertaining to the liver often start in hepato or hepatic from the Greek language Greek word for liver, hepar . Several distinct types of tumors can develop in the liver because the liver is made up of various cell types. These growths can be benign or malignant cancerous . They may be discovered on medical imaging even for a different reason than the cancer itself , or may be present in patients as an abdominal mass, hepatomegaly , abdominal pain , jaundice , or some other liver dysfunction. Classification There are many forms of liver tumors Malignant cancerous File Ultrasound Scan ND 1230124453 1300210.png thumb 230px Large HCC filling almost entire of right lobe main Liver cancer Most cases are metastases from other tumor s, frequently of the GI tract like colon cancer , Carcinoid syndrome carcinoid tumors mainly of the Vermiform appendix appendix , etc . , but also from breast cancer , ovarian cancer , lung cancer , renal cancer , prostate cancer , etc . The most frequent, malignant, primary liver cancer is hepatocellular carcinoma also named hepatoma , which is a misnomer because adenoma s are usually benign . More rare primary forms of liver cancer include cholangiocarcinoma , mixed tumors, tumors of Mesenchymal stem cell mesenchymal tissue, sarcoma and hepatoblastoma , a rare malignant tumor in children. Benign There are several types of benign liver tumor. Hemangioma s These are the most common type of benign liver tumor, found in up to 7 of autopsy specimens. They start in blood vessels. Most of these tumors do not cause symptoms and do not need treatment. Some may bleed and need to be ... more details
test to elevate serotonin levels and cause symptoms of carcinoid syndrome . It provokes flushing ... elevated biochemical markers for carcinoid syndrome. In addition, it has been used to stimulate ectopic ... more details
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