Infobox ship begin Infobox ship image Ship image Ship caption Infobox ship career Hide header Ship name 1892 1913 PS Lune br 1913 1923 PS Melcome Regis Ship owner 1892 1913 Lancashire and Yorkshire Railway br 1913 1923 Cosen & Company, Weymouth Ship operator 1892 1913 Lancashire and Yorkshire Railway br 1913 1923 Cosen & Company, Weymouth Ship registry flagicon UK civil Ship route 1892 1913 Fleetwood Heysham and Blackpool Ship ordered Ship builder TB Seath of Rutherglen Ship original cost Ship yard number Ship way number Ship laid down Ship launched 1892 Ship completed Ship christened Ship acquired Ship maiden voyage Ship in service Ship out of service 1923 Ship identification Ship fate Scrapped Ship status Ship notes Infobox ship characteristics Hide header Header caption Ship type Ship tonnage GRT 252 first yes Ship displacement Ship length convert 129 ft m abbr on Ship beam convert 24 ft m abbr on Ship draught Ship depth Ship decks Ship deck clearance Ship ramps Ship ice class Ship power Ship propulsion Ship speed Ship capacity Ship crew Ship notes PS Lune was a paddle steamer passenger vessel operated by the Lancashire and Yorkshire Railway from 1892 to 1913. ref Railway and Other Steamers, Duckworth. 1962 ref History She was built by TB Seath of Rutherglen for the Lancashire and Yorkshire Railway in 1892. She operated a passenger service from Fleetwood to Heysham and Blackpool. In June 1913 she was sold to Cosens & Co Ltd in Weymouth and operated as Melcome Regis . She was scrapped in 1923. References reflist LYR Ships LNWR Ships Category 1892 ships Category Passenger ships of the United Kingdom Category Steamships Category Clyde built ships Category Ships of the London and North Western Railway Category Ships of the Lancashire and Yorkshire Railway Category Paddle steamers DEFAULTSORT Lune ... more details
6 To his cosen, Robert Parry he left his lexicon and other books 7 To his loving cosen, Richard Parry he left a gold ring 8 To his cosen Mary Parry , wife of Richard, he left a money legacy 9 He appointed his cosen, Robert Parry as overseer of his will Works Bishop Parry wrote a book entitled David ... more details
File Lady Elizabeth Carey tomb.jpg thumb right 200px Monument to Lady Elizabeth Carey , also known as Elizabeth Danvers n e Neville in St Michael s Church, Church Stowe Stowe , Northamptonshire, England. Elizabeth Danvers n e Neville , later Elizabeth Carey by remarriage born 1545 50 &ndash 1630, Stowe Nine Churches Stowe , Northamptonshire was a learn d English noblewoman. The antiquarian and biographer John Aubrey , whose ancestor she was, ref name Emerson describes her in his Brief Lives 1693 , states that she had Chaucer at her fingers ends and was fluent in Italian. ref cite web url http www.brooklynmuseum.org eascfa dinner party heritage floor elizabeth danviers.php title Elizabeth Danviers date April 20, 2007 work The Dinner Party Database of notable women publisher Brooklyn Museum accessdate 2009 05 31 ref blockquote Elizabeth Danvers his mother, an Italian, prodigeous parts for a woman. Have heard my fathers mother say that she had Chaucer at her fingers ends. A great Politician great Witt and spirit, but revengeful knew how to manage her estate as well as any man understood jewels as well as any Jeweller. Very Beautiful, but only short sighted. To obtain Pardons for her Sonnes she maryed Sir Edmund Carey, cosen german to Queen Elizabeth, but kept him to hard meate. ref cite book last Aubrey first John coauthors Oliver Lawson Dick, Edmund FRW Wilson Contributor Edmund FRW Wilson title Aubrey s Brief Lives publisher Reprint, illustrated, Published by David R. Godine Publisher date 1999 isbn 1567920632 url http books.google.com books?id 5UPpQ4bAwdgC ref blockquote Elizabeth Danvers was the daughter of John Nevill, 4th Baron Latymer c. 1520 1577 and Lucy Somerset. She first married Sir John Danvers, Knight Knt. , of Dauntsey , Wiltshire died 10 December 1594 and had three sons Charles Danvers Charles , Henry Danvers, 1st Earl of Danby Henry and John Danvers John and seven daughters. ref cite web url http www.tudorplace.com.ar NEVILLE3.htm Elizabeth 20NEVILLE2 ... more details
The Countess of Pembroke s Arcadia , also known simply as the Arcadia or the Old Arcadia , is a long prose work by Sir Philip Sidney written towards the end of the 16th century, and later published in several versions. It is Sidney s most ambitious literary work, by far, and as significant in its own way as his sonnet s. The work is a romance that combines pastoral elements with a mood derived from the Hellenistic model of Heliodorus . In the work, that is, a highly idealized version of the shepherd s life adjoins not always naturally with stories of jousts, political treachery, kidnappings, battles, and rapes. As published, the narrative follows the Greek model stories are nested within each other, and different storylines are intertwined. Composition and publication Sidney s Arcadia has a history that is unusually complex even for its time. The Old Arcadia Sidney may have begun an early draft in the late 1570s, when he was in his twenties. His own comments indicate that his purpose was humble he asserts that he intended only to entertain his sister, Mary Sidney Mary Herbert , the Countess of Pembroke. This version is narrated in chronological order, with sets of poems separating the books from each other. It seems likely that Sidney finished this version while staying at Herbert s estate during a temporary eclipse at court in 1580. In 1588, Fulke Greville appears to have appealed to Francis Walsingham to prevent an unauthorized publication of parts of the original, as we learn from a letter that also serves as evidence for the circulation of Arcadia in manuscript form blockquote Sir this day one Ponsonby a bookbinder in Paul s Churchyard, came to me, and told me that there was one in hand to print, Sir Philip Sidney s old Arcadia asking me if it were done with your honour s con sent or any other of his friends I told him to my knowledge no, then he advised me to give warning of it, either to the Archbishop or Doctor Cosen, who have as he says a copy of it to perus ... more details
PBB geneid 2017 Cortactin from u cort u ical u actin u binding protein is a monomeric protein located in the cytoplasm of cells that can be activated by external stimuli to promote polymerization and rearrangement of the actin cytoskeleton , especially the actin cortex around the cellular periphery. ref name pmid16990456 cite journal author Cosen Binker LI, Kapus A title Cortactin the gray eminence of the cytoskeleton journal Physiology Bethesda volume 21 issue 5 pages 352 61 year 2006 month October pmid 16990456 doi 10.1152 physiol.00012.2006 url issn ref ref name pmid18615630 cite journal author Ammer AG, Weed SA title Cortactin branches out roles in regulating protrusive actin dynamics journal Cell Motil. Cytoskeleton volume 65 issue 9 pages 687 707 year 2008 month September pmid 18615630 doi 10.1002 cm.20296 url issn pmc 2561250 ref It is present in all cell types. When activated, it will recruit Arp2 3 complex proteins to existing actin microfilaments, facilitating and stabilizing nucleation sites for actin branching. Cortactin is important in promoting lamellipodia formation, invadopodia formation, cell migration , and endocytosis . Gene In humans, cortactin is encoded by the CTTN gene on chromosome 11. ref name pmid7685625 cite journal author Brookes S, Lammie GA, Schuuring E, de Boer C, Michalides R, Dickson C, Peters G title Amplified region of chromosome band 11q13 in breast and squamous cell carcinomas encompasses three CpG islands telomeric of FGF3, including the expressed gene EMS1 journal Genes Chromosomes Cancer volume 6 issue 4 pages 222 31 year 1993 month April pmid 7685625 doi 10.1002 gcc.2870060406 url issn ref Structure Cortactin is a thin, elongated monomer that consists of an amino terminal acidic NTA region 37 residue long segments that are highly conserved among cortactin proteins of all species and repeated up to 6.5 times in tandem cortactin repeats a proline rich region and an SH3 domain . This basic structure is highly conserved among all ... more details
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