FlashPt Autoignition Cytidinetriphosphate is a pyrimidine nucleoside triphosphate . CTP is a Substrate ... Aspartate carbamoyltransferase See also cytidine pyrimidine biosynthesis CTP synthase Nucleobases, nucleosides, and nucleotides DEFAULTSORT CytidineTriphosphate Category Nucleotides Category Pyrimidones ... de Cytidintriphosphat es Citidina trifosfato fr Cytidinetriphosphate gl Citid n trifosfato ... triphosphate ATP , but its role in the organism is more specific than that of ATP. This statement ... more details
Chembox Hazards MainHazards FlashPt Autoignition Cytidine is a nucleoside molecule that is formed when ... bond . Cytidine is a component of RNA . If cytosine is attached to a deoxyribose ring, it is known as a deoxycytidine . Dietary sources of cytidine Dietary sources of cytidine include foods with high ... such as beer. During digestion, RNA rich foods are broken down into ribosyl pyrimidines cytidine and uridine , which are absorbed intact. ref name Jonas In humans, dietary cytidine is converted into uridine ... 6 doi 10.1016 S0006 2952 00 00436 6 ref which is probably the compound behind cytidine s metabolic effects. Cytidine Analogs Cytidine has a number of analogs. KP 1461 is an Anti HIV drug that works ... Ribosides bg ca Citidina cs Cytidin de Cytidin es Citidina fa fr Cytidine gl Citidina it Citidina lt Citidinas hu Citidin nl Cytidine ja oc Citidina pt Citidina ru sl ... more details
to Cytidine diphosphate by the enzyme CMP kinase, with Adenosine triphosphate or Guanosine triphosphate guanine triphosphate donating the phosphate group. Since Cytidinetriphosphate is generated by amination of uridine triphosphate , the main source of CMP is from RNA being decomposed, e.g. ... of phosphoric acid with the nucleoside cytidine . CMP consists of the phosphate Functional ..., and nucleotides DEFAULTSORT Cytidine Monophosphate Category Nucleotides Category Pyrimidones Biochem ... fr Cytidine monophosphate gl Citid n monofosfato it Citosina monofosfato nl Cytidinemonofosfaat ... more details
PBB geneid 978 Cytidine deaminase is an enzyme that in humans is encoded by the CDA gene . ref name pmid8422236 ... cytidine deaminase CDD and its use as a marker of monocyte macrophage differentiation journal ... S, Bruschi M, Garattini E title Isolation and characterization of the gene coding for human cytidine ... 9878810 pmc doi ref ref name entrez cite web title Entrez Gene CDA cytidine deaminase url http www.ncbi.nlm.nih.gov ... of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases ... of certain childhood leukemias. ref name entrez cite web title Entrez Gene CDA cytidine deaminase ... R title On the interaction of 3,4,5,6 tetrahydrouridine with human liver cytidine deaminase. journal ... journal author Lalibert J, Momparler RL title Human cytidine deaminase purification of enzyme, cloning ... of the human cytidine deaminase CDA gene to chromosome 1 band p35 p36.2. journal Genomics volume ... by human cytidine deaminase requires the catalytic function of the protein. journal Blood volume ... A, et al. title Intracellular localization of human cytidine deaminase. Identification of a functional ... adenosine deaminase and cytidine deaminase activities in patients with systemic lupus erythematosus ... induced cytidine deaminase deaminates deoxycytidine on single stranded DNA but requires the action of RNase ... Expression of cytidine deaminase mRNA in bone marrow cells from patients with acute leukemia journal ... cytidine deaminase. journal Nucleosides Nucleotides Nucleic Acids volume 22 issue 5 8 pages 1535 ... A, et al. title Human cytidine deaminase understanding the catalytic mechanism. journal Nucleosides ... NCN 120023029 cite journal author Ge Y, Jensen TL, Stout ML, et al. title The role of cytidine deaminase ... al. title Functional properties of subunit interactions in human cytidine deaminase. journal Protein ... SJ, Fromme JC, Verdine GL title Structure of human cytidine deaminase bound to a potent inhibitor ... cytidine deaminase. journal Protein Eng. Des. Sel. volume 17 issue 12 pages 871 7 year 2005 pmid ... more details
chembox verifiedrevid 443555075 ImageFile Cytidindiphosphat protoniert.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 5902 InChI 1 C9H15N3O11P2 c10 5 1 2 12 9 15 11 5 8 7 14 6 13 4 22 8 3 21 25 19,20 23 24 16,17 18 h1 2,4,6 8,13 14H,3H2, H,19,20 H2,10,11,15 H2,16,17,18 t4 ,6 ,7 ,8 m1 s1 InChIKey ZWIADYZPOWUWEW XVFCMESIBF ChEMBL Ref ebicite correct EBI ChEMBL 425252 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H15N3O11P2 c10 5 1 2 12 9 15 11 5 8 7 14 6 13 4 22 8 3 21 25 19,20 23 24 16,17 18 h1 2,4,6 8,13 14H,3H2, H,19,20 H2,10,11,15 H2,16,17,18 t4 ,6 ,7 ,8 m1 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey ZWIADYZPOWUWEW XVFCMESISA N CASNo 63 38 7 CASNo Ref cascite correct CAS CASOther br 34393 59 4 disodium salt NOT CAS verified PubChem 290 ChEBI Ref ebicite correct EBI ChEBI 17239 SMILES O P O O OP O O OC C H 2O C H N 1C O N C N C C 1 C H O C H 2O Section2 Chembox Properties Formula C sub 9 sub H sub 15 sub N sub 3 sub O sub 11 sub P sub 2 sub MolarMass 403.176422 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Cytidine diphosphate , abbreviated CDP , is a nucleoside diphosphate . It is an ester of pyrophosphoric acid with the nucleoside cytidine . CDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase cytosine . See also Nucleoside Nucleotide DNA RNA Oligonucleotide External links Nucleobases, nucleosides, and nucleotides Category Nucleotides Category Pyrimidones biochem stub ca Difosfat de citidina da Cytidindifosfat de Cytidindiphosphat fa fr Cytidine diphosphate gl Citid n difosfato it Citosindifosfato nl Cytidinedifosfaat ja sr Citidin difosfat zh ... more details
unreferenced date February 2007 Nucleoside triphosphate NTP is a molecule containing a nucleoside bound to three phosphate s. Natural nucleoside triphosphates include adenosine triphosphate ATP , guanosine triphosphate GTP , cytidinetriphosphate CTP , 5 methyluridine triphosphate m sup 5 sup UTP , and uridine triphosphate UTP . These terms refer to those nucleoside triphosphates that contain ribose. The nucleoside triphosphates containing deoxyribose take prefix deoxy in their names and small d in their abbreviations deoxyadenosine triphosphate dATP , deoxyguanosine triphosphate dGTP , deoxycytidine triphosphate dCTP , deoxythymidine triphosphate dTTP and deoxyuridine triphosphate . Check the entry nucleoside for table and description of these compounds. Apart from d ATP, d GTP, d CTP, d TTP and d UTP, there are other less abundant NTPs, such as intermediates of nucleotide metabolism, but also rare natural nucleotides or even artificial nucleotides . The rare NTP are tautomeric forms of the NTPs. They cause mismatched base pairing during DNA replication. For example, a tautomeric form of cytosine is capable of forming 3 h bonds with adenine, and it will spontaneously revert to its original cytosine form, causing a mismatch. By a similar token, the deamination of cytosine leads to uracil, whereas a deamination of a commonly encountered in eukaryotes 5 methylcytosine will lead to thymine. However, the 5 to 3 DNA replication ensures that these mismatched bases are excised. Nucleotide derivatives are necessary for life, as they are building blocks of nucleic acid s and have thousands of other roles in cell metabolism and regulation. ATP is a major source of cellular energy. GTP is a very frequent cofactor of enzymes and proteins. NTPs generally provide energy and phosphate group for phosphorylations. Generally nucleoside s are nucleotide s sugar covalently bonded to a nitrogenous ... diphosphate NDP , and for three, it is a nucleoside triphosphate NTP . The nucleotides that contain ... more details
chembox verifiedrevid 384065455 ImageFile Ara CTP.svg ImageSize IUPACName OtherNames Ara CTP, Cytarabine triphosphate, br Cytosine arabinoside triphosphate Reference ref name pubchem http pubchem.ncbi.nlm.nih.gov summary summary.cgi?cid 25774 Ara CTP Compound Summary , PubChem . ref Section1 Chembox Identifiers CASNo 13191 15 6 PubChem 25774 SMILES C1 CN C O N C1N C2C C C O2 COP O O OP O O OP O O O O O MeSHName Arabinofuranosylcytosine triphosphate Section2 Chembox Properties Formula C sub 9 sub H sub 16 sub N sub 3 sub O sub 14 sub P sub 3 sub MolarMass 483.156323 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Arabinofuranosylcytosine triphosphate is a nucleotide that inhibits the protein biosynthesis synthesis of DNA . It is the biologically active form of cytarabine . ref name pubchem References reflist Nucleobases, nucleosides, and nucleotides Category Nucleotides Category Pyrimidones organic compound stub fa zh ... more details
chembox Verifiedfields changed Watchedfields changed verifiedrevid ImageFile Desoxythymidintriphosphat protoniert.svg ImageSize IUPACName 2R,3S,5R 3 hydroxy 5 5 methyl 2,4 dioxopyrimidin 1 yl oxolan 2 yl methyl hydroxy phosphonooxyphosphoryl hydrogen phosphate OtherNames dTTP, 2 deoxythymidine triphosphate Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID 58493 ChEMBL Ref ebicite changed EBI ChEMBL 363559 InChI InChIKey StdInChI Ref stdinchicite correct chemspider StdInChI StdInChIKey Ref stdinchicite correct chemspider StdInChIKey CASNo Ref cascite changed ?? CASNo 365 08 2 PubChem 64968 IUPHAR ligand SMILES CC1 CN C O NC1 O C2CC C O2 COP O O OP O O OP O O O O MeSHName thymidine 5 triphosphate Section2 Chembox Properties Formula C sub 10 sub H sub 17 sub N sub 2 sub O sub 14 sub P sub 3 sub MolarMass 482.168 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxythymidine triphosphate dTTP is one of the five nucleoside triphosphate s that are used in the in vivo synthesis of DNA . Unlike the other deoxyribonucleotide triphosphates, thymidine triphosphate does not contain the deoxy prefix in its name. ref cite book title The ACS style guide effective communication of scientific information year 2006 publisher American Chemical Society location Washington, D.C. isbn 9780841239999 edition 3rd editor Coghill, Anne M. Garson, Lorrin R. page 244 ref The corresponding ribonucleoside triphosphate is called 5 methyluridine triphosphate . It can be used by DNA ligase to create overlapping sticky ends so that protruding ends of opened microbial plasmid s may be closed up. Reflist reflist Nucleobases, nucleosides, and nucleotides Category Nucleotides genetics stub ca Trifosfat de timidina de Desoxythymidintriphosphat es Timidina trifosfato fa fr Thymidine triphosphate gl Desoxitimidina trifosfato nl Thymidinetrifosfaat ja sr Timidin trifosfat zh ... more details
H 3 C H C H C H O3 CO P O O O P O O OP O O O O O nH c nc2 O N MeSHName Guanosine triphosphate Section2 ... Hazards Solubility MainHazards FlashPt Autoignition Guanosine 5 triphosphate GTP is a purine nucleoside triphosphate . It can act as a substrate for the synthesis of RNA during the transcription genetics ... attached to the 1 and the triphosphate moiety attached to the 5 carbons of the ribose. It also ... triphosphate ATP , but more specific. It is used as a source of energy for protein biosynthesis ... acid cycle . This is tantamount to the generation of one molecule of Adenosine triphosphate ... guanosine triphosphate redirects here Cyclic guanosine triphosphate cGTP helps cyclic adenosine monophosphate ... Triphosphate Category Nucleotides Category Purines bg ca Trifosfat de guanosina ... trifosfato fa fr Guanosine triphosphate gl Guanos n trifosfato it Guanosintrifosfato ... more details
triphosphate and thiamine triphosphatase activities from bacteria to mammals. Cell Mol Life Sci 60 ... Ref1 ref name Ref3 Lakaye B, Wirtzfeld B, Wins P, Grisar T & Bettendorff L. 2004 Thiamine triphosphate ... triphosphate deficiency in subacute necrotizing encephalomyelopathy. Science 164 74 75 pmid 5773712 ..., suppression of the carbon source leads to the accumulation, of adenosine thiamine triphosphate AThTP ... B. & Bettendorff L. 2010 Thiamine triphosphate synthesis in the rat brain is mitochondrial and coupled ... be converted into ThDP by thiamine diphosphate kinase . History Thiamine triphosphate ThTP was chemically synthesized in 1948 at a time when the only organic triphosphate known was ATP. ref Velluz L ... s yeast. ref Kiessling K. H. 1953 Thiamine triphosphate in baker s yeast Nature 172 1187 1188. ref ... unphosphorylated . ref Yusa T. 1962 Studies on thiamine triphosphate II. Thiamine triphosphate ... more details
Refimprove date December 2009 Drugbox Verifiedfields changed verifiedrevid 457479092 IUPAC name 2R,3S,5R 3 hydroxy 5 5 methyl 2,4 dioxopyrimidin 1 yl oxolan 2 yl methyl hydroxy phosphonooxyphosphoryl hydrogen phosphate image 5 Methyluridintriphosphat protoniert.svg alt caption Clinical data tradename pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA OTC, Rx only, Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD Benz POM, CD Anab POM or CD Inv POM legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CAS number Ref cascite changed ?? CAS number ? ATCvet ATC prefix none if uncategorised ATC suffix PubChem DrugBank Ref drugbankcite correct drugbank DrugBank ChEMBL Ref ebicite changed EBI ChEMBL 607677 Chemical data chemical formula C10 H17 N2 O15 P3 molecular weight 498.2 g mol smiles CC1 CN C2O C H COP O O OP O O OP O O O C H O C H 2O C O NC1 O 5 Methyluridine triphosphate or m sup 5 sup UTP is one of five nucleoside triphosphate s. It is the ribonucleoside triphosphate of thymidine , but the 5 methyluridine nomenclature is used because the term thymidine triphosphate is used for the deoxyribonucleoside by convention. ref cite book title The ACS style guide effective communication of scientific information year 2006 publisher American Chemical Society location Washington, D.C. isbn 9780841239999 edition 3rd editor Coghill, Anne M. Garson, Lorrin R. page 244 ref References reflist Nucleobases, nucleosides, and nucleotides DEFAULTSORT Thymidine Triphosphate Category Nucleotides Biochem stub ca Trifosfat de timidina de Desoxythymidintriphosphat fr Thymidine triphosphate nl Thymidinetrifosfaat ja sr Timidin trifosfat zh ... more details
Unreferenced date December 2009 Expert subject Chemistry date November 2008 Chembox verifiedrevid 417224336 ImageFile Desoxycytidintriphosphat protoniert.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo Ref cascite correct CAS CASNo 2056 98 6 PubChem 65091 SMILES C1C C OC1N2C CC NC2 O N COP O O OP O O OP O O O O Section2 Chembox Properties Formula C sub 9 sub H sub 16 sub N sub 3 sub O sub 13 sub P sub 3 sub MolarMass 467.156923 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxycytidine triphosphate dCTP is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction . e.g. A chemical equation can be written that represents the process DNA sub n sub dCTP DNA sub n sub C PP sub i sub That is, dCTP has the PP sub i sub pyrophosphate cleaved off and the Deoxycytidine monophosphate dCMP is incorporated into the DNA strand at the 3 end. Subsequent hydrolysis of the PP sub i sub drives the equilibrium of the reaction toward the right side, i.e. incorporation of the nucleotide in the growing DNA chain. It is stored at 20 degrees Celsius. See also DNA Replication Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxycytidine Triphosphate Category Molecular biology Category Nucleotides Biochemistry stub ca Trifosfat de desoxicitidina de Desoxycytidintriphosphat fa gl Desoxicitidina trifosfato nl Deoxycytidinetrifosfaat sr Dezoksicitidin trifosfat zh ... more details
Chembox Verifiedfields changed verifiedrevid 440114883 ImageFile Desoxyguanosintriphosphat protoniert.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers PubChem 65103 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 58613 ChEMBL Ref ebicite changed EBI ChEMBL 477486 ChEBI Ref ebicite changed EBI ChEBI 16497 SMILES O P O O OP O O OP O O OC C H 3O C H n1cnc2c1NC N C2 O N C C H 3O StdInChI Ref stdinchicite correct chemspider StdInChI 1S C10H16N5O13P3 c11 10 13 8 7 9 17 14 10 12 3 15 8 6 1 4 16 5 26 6 2 25 30 21,22 28 31 23,24 27 29 18,19 20 h3 6,16H,1 2H2, H,21,22 H,23,24 H2,18,19,20 H3,11,13,14,17 t4 ,5 ,6 m0 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey HAAZLUGHYHWQIW KVQBGUIXSA N Section2 Chembox Properties Formula C sub 10 sub H sub 16 sub N sub 5 sub O sub 13 sub P sub 3 sub MolarMass 507.181023 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxyguanosine triphosphate ref Lehninger4th ref dGTP is a nucleoside triphosphate , and a nucleotide precursor used in cells for DNA replication DNA synthesis . The substance is used in the polymerase chain reaction technique, in sequencing , and in cloning . It is also the competitor of inhibition onset by acyclovir in the treatment of Herpes simplex virus HSV virus . ref name pmid6285704 cite journal author Furman PA, Lambe CU, Nelson DJ title Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1 journal Am. J. Med. volume 73 issue 1A pages 14 7 year 1982 month July pmid 6285704 doi 10.1016 0002 9343 82 90056 0 url issn ref References reflist 2 Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxyguanosine Triphosphate Category Nucleotides Organic compound stub ca Trifosfat de desoxiguanosina de Desoxyguanosintriphosphat fa gl Desoxiguanosina trifosfato nl Deoxyguanosinetrifosfaat sr Dezoksiguanozin trifosfat zh ... more details
. ref cite journal last1 Corbridge first1 D. E. C. title The crystal structure of sodium triphosphate ... structure of sodium triphosphate, Na5P3O10, phase II journal Acta Crystallographica volume ... are known including the cyclic triphosphate P sub 3 sub O sub 9 sub sup 3 sup . It binds strongly to metal cations as both a bidentate and tridentate chelating agent . Image Triphosphate chelation.svg thumb 180px left Chelation of a metal cation by triphosphate. Uses In detergents The majority of STPP ..., Adenosine triphosphate ATP , a related derivative of triphosphate, is essential for life ... more details
Orphan date February 2009 chembox verifiedrevid 402880365 ImageFile xanthosine triphosphate.png ImageSize 200px IUPACName 2 R ,3 S ,4 R 5 2,6 dioxo 3 H purin 9 yl 3,4 dihydroxy 2 tetrahydrofuranyl methyl hydroxy phosphonooxyphosphoryl hydrogen phosphate OtherNames Section1 Chembox Identifiers InChI 1 C10H12N4O6.3H3O4P c15 1 3 5 16 6 17 9 20 3 14 2 11 4 7 14 12 10 19 13 8 4 18 3 1 5 2,3 4 h2 3,5 6,9,15 17H,1H2, H2,12,13,18,19 3 H3,1,2,3,4 t3 ,5 ,6 ,9 m1... s1 InChIKey BKBQKVXTMZOVRH CYCLDIHTBT StdInChI Ref stdinchicite correct chemspider StdInChI 1S C10H12N4O6.3H3O4P c15 1 3 5 16 6 17 9 20 3 14 2 11 4 7 14 12 10 19 13 8 4 18 3 1 5 2,3 4 h2 3,5 6,9,15 17H,1H2, H2,12,13,18,19 3 H3,1,2,3,4 t3 ,5 ,6 ,9 m1... s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey BKBQKVXTMZOVRH CYCLDIHTSA N CASNo 6253 56 1 PubChem 121887 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 19980202 SMILES OP O O O.OP O O O.OP O O O.O C3Nc2c ncn2 C H 1O C H CO C H O C H 1O C O N3 Section2 Chembox Properties Formula C sub 10 sub H sub 15 sub N sub 4 sub O sub 15 sub P sub 3 sub MolarMass 524.17 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Xanthosine 5 triphosphate XTP is a nucleotide that is not produced by and has no known function in living cells. Uses of XTP are, in general, limited to experimental procedures on enzymes that bind other nucleotides. See also Xanthosine Xanthosine monophosphate Nucleobases, nucleosides, and nucleotides Category Nucleotides Category Purines organic compound stub biochemistry stub fa fr Xanthosine triphosphate ... more details
Orphan date January 2010 Chembox verifiedrevid 443356640 ImageFile 7,8 Dihydroneopterin triphosphate.png ImageSize 200px IUPACName OtherNames DHNTP Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 108735 InChI 1 C9H16N5O13P3 c10 9 13 7 5 8 17 14 9 12 3 1 11 7 6 16 4 15 2 25 29 21,22 27 30 23,24 26 28 18,19 20 h4,6,15 16H,1 2H2, H,21,22 H,23,24 H2,18,19,20 H4,10,11,13,14,17 t4 ,6 m1 s1 InChIKey DGGUVLXVLHAAGT XINAWCOVBB SMILES1 O P O O OP O O OP O O OC C H O C H O C 1 N C 2C O N C NC 2NC 1 N StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H16N5O13P3 c10 9 13 7 5 8 17 14 9 12 3 1 11 7 6 16 4 15 2 25 29 21,22 27 30 23,24 26 28 18,19 20 h4,6,15 16H,1 2H2, H,21,22 H,23,24 H2,18,19,20 H4,10,11,13,14,17 t4 ,6 m1 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey DGGUVLXVLHAAGT XINAWCOVSA N CASNo 17088 65 2 PubChem ChEBI Ref ebicite correct EBI ChEBI 18372 SMILES O C1C2 C NCC C H C H COP OP OP O O O O O O O O O N2 NC N N1 Section2 Chembox Properties C 9 H 16 N 5 O 13 P 3 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition 7,8 Dihydroneopterin triphosphate DHNTP is an intermediate in tetrahydrobiopterin biosynthesis . References Unreferenced date September 2009 Reflist DEFAULTSORT Dihydroneopterin triphosphate, 7,8 Category Organophosphates Category Pteridines organic compound stub ja 7,8 ... more details
5 triphosphate ATP is a multifunctional nucleoside triphosphate used in cell biology cells as a coenzyme ... sugar and three phosphate groups triphosphate . The phosphoryl groups, starting with the group ... title Thermodynamics of the hydrolysis of adenosine 5 triphosphate to adenosine 5 diphosphate url http ... and Company year 2002 isbn 0 7167 1843 X ref Ionization in biological systems ATP adenosine triphosphate ... molecule of the ATP equivalent guanosine triphosphate GTP through substrate level phosphorylation ...?cid 5957 PubChem entry for Adenosine Triphosphate http www.genome.jp dbget bin www bget?cpd C00002 KEGG entry for Adenosine Triphosphate Nucleobases, nucleosides, and nucleotides Enzyme cofactors Neurotransmitters good article DEFAULTSORT Adenosine Triphosphate Category Cellular respiration ... eo Adenozina trifosfato eu Adenosina trifosfato fa fr Ad nosine triphosphate gl Adenos n ... Adenosina trifosfat is Aden s n r fosfat it Adenosina trifosfato he ATP jv Adenosin Triphosphate ka ... Adenozintrifosfat simple Adenosine triphosphate sk Adenoz ntrifosf t sl Adenozin trifosfat sr ... more details
Chembox Verifiedfields changed Watchedfields changed verifiedrevid 400127872 ImageFile Cytidine diphosphate glucose.png ImageSize 200px IUPACName nowiki nowiki 2 R ,3 S ,4 R ,5 R 5 4 amino 2 oxopyrimidin 1 yl 3,4 dihydroxyoxolan 2 yl methoxy hydroxyphosphoryl 2 R ,3 R ,4 S ,5 S ,6 R 3,4,5 trihydroxy 6 hydroxymethyl oxan 2 yl hydrogen phosphate OtherNames CDP glucose Section1 Chembox Identifiers CASNo Ref cascite correct ?? CASNo 2906 23 2 PubChem 439244 SMILES C1 CN C O N C1N C H 2 C H C H C H O2 COP O O OP O O O C H 3 C H C H C H C H O3 CO O O O O O ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID 388381 SMILES O P O C H 1O C H C H O C H O C H 1O CO O OP O O OC C H 3O C H N2 C C C N C2 O N C H O C H 3O StdInChI Ref stdinchicite changed chemspider StdInChI 1S C15H25N3O16P2 c16 7 1 2 18 15 25 17 7 13 11 23 9 21 6 31 13 4 30 35 26,27 34 36 28,29 33 14 12 24 10 22 8 20 5 3 19 32 14 h1 2,5 6,8 14,19 24H,3 4H2, H,26,27 H,28,29 H2,16,17,25 t5 ,6 ,8 ,9 ,10 ,11 ,12 ,13 ,14 m1 s1 StdInChIKey Ref stdinchicite changed chemspider StdInChIKey CGPHZDRCVSLMCF JZMIEXBBSA N Section2 Chembox Properties C 15 H 25 N 3 O 16 P 2 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Cytidine diphosphate glucose , often abbreviated CDP glucose , is a nucleotide linked sugar consisting of cytidine diphospahte and glucose. ref name Reeves cite journal author Samuel G, Reeves P title Biosynthesis of O antigens genes and pathways involved in nucleotide sugar precursor synthesis and O antigen assembly journal Carbohydr. Res. volume 338 issue 23 pages 2503 19 year 2003 pmid 14670712 doi 10.1016 j.carres.2003.07.009 ref ref name Liu cite journal doi 10.1146 annurev.biochem.71.110601.135339 author Xue M. He and Hung wen Liu title Formation ... 71 issue pages 701 754 year 2002 pmid 12045109 ref Biosynthesis CDP glucose is produced from cytidinetriphosphate CTP and glucose 1 phosphate by the enzyme glucose 1 phosphate cytidylyltransferase ... more details
Activation induced cytidine deaminase AID is a 24 kDa Citation needed date August 2011 enzyme that creates mutations in DNA . AID removes the amino group from a cytidine base, turning it into a uridine which is recognized as a thymidine . In other words, it changes a CG base pair into a UG base pair, which the cell s DNA repair machinery recognizes as a TG base pair, and finally ends up as a TA base pair. In B cells in the lymph nodes, AID causes mutations that produce antibody diversity, but that same mutation process leads to B cell lymphoma. ref cite journal author Georg Lenz and Louis M. Staudt title Aggressive Lymphomas journal N Engl J Med volume 362 issue 15 pages 1417 year 2010 pmid 20393178 doi 10.1056 NEJMra0807082 url http content.nejm.org cgi content short 362 15 1417 ref AID is currently thought to be the master regulator of secondary antibody diversification. It is involved in the initiation of three separate immunoglobulin Ig diversification processes somatic hypermutation SHM , in which the antibody genes are shuffled to provide enough diversity to deal with millions of antigens class switch recombination CSR , in which B cells change their expression from IgM to IgG or other immune types and gene conversion GC . AID has been shown in vitro to be active on single stranded DNA ref Bransteitter et al. PNAS 100 7 4102 4107 ref , and has been shown to require active Transcription genetics transcription in order to exert its deaminating activity. The involvement of Cis regulatory factors is suspected as AID activity is several orders of magnitude higher in the immunoglobulin variable region than other regions of the genome that are known to be subject to AID activity. This is also true of artificial reporter constructs and transgene s that have been integrated ... cytidine in the target DNA. Cytidines located within hotspot motifs are preferentially deaminated WRCY motifs W adenosine or thymidine, R purine, C cytidine, Y pyrimidine, or the inverse RGYW G guanidine ... more details
enzyme Name nucleoside triphosphate adenylate kinase EC number 2.7.4.10 CAS number 9026 74 8 IUBMB EC number 2 7 4 10 GO code 0046899 image width caption Orphan date February 2009 In enzymology , a nucleoside triphosphate adenylate kinase EC number 2.7.4.10 is an enzyme that catalysis catalyzes the chemical reaction nucleoside triphosphate AMP math rightleftharpoons math nucleoside diphosphate ADP Thus, the two substrate biochemistry substrates of this enzyme are nucleoside triphosphate and adenosine monophosphate AMP , whereas its two product chemistry products are nucleoside diphosphate and adenosine diphosphate ADP . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with a phosphate group as acceptor. The systematic name of this enzyme class is nucleoside triphosphate AMP phosphotransferase . Other names in common use include guanosine triphosphate adenylate kinase , nucleoside triphosphate adenosine monophosphate transphosphorylase , GTP AMP phosphotransferase , and isozyme 3 of adenylate kinase . This enzyme participates in pyrimidine metabolism . Structural studies As of late 2007, two tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1ZD8 and PDB link 2AK3 . References reflist 1 cite journal author Albrecht GJ date 1970 title Purification and properties of nucleoside triphosphate adenosine monophosphate transphosphorylase from beef heart mitochondria journal Biochemistry. volume 9 pages 2462&ndash 70 pmid 5423264 doi 10.1021 bi00814a011 issue 12 cite journal author CHIGA M, ROGERS AE, PLAUT GW date 1961 title Nucleotide transphosphorylases from liver. II. Purification and properties of a 6 oxypurine nucleoside triphosphate adenosine monophosphate transphosphorylase from swine liver journal J. Biol. Chem. volume 236 pages 1800&ndash 5 pmid 13693071 enzyme stub Category EC 2.7.4 Category Enzymes of known ... more details
enzyme Name guanosine triphosphate guanylyltransferase EC number 2.7.7.45 CAS number 54576 89 5 IUBMB EC number 2 7 7 45 GO code 0047351 image width caption In enzymology , a guanosine triphosphate guanylyltransferase EC number 2.7.7.45 is an enzyme that catalysis catalyzes the chemical reaction 2 GTP math rightleftharpoons math diphosphate P sub 1 sub ,P sub 4 sub bis 5 guanosyl tetraphosphate Hence, this enzyme has one substrate biochemistry substrate , guanosine triphosphate GTP , and two product chemistry products , diphosphate and P1,P4 bis 5 guanosyl tetraphosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing nucleotide groups nucleotidyltransferase s . The systematic name of this enzyme class is GTP GTP guanylyltransferase . Other names in common use include diguanosine tetraphosphate synthetase , GTP GTP guanylyltransferase , Gp4G synthetase , and guanosine triphosphate guanose triphosphate guanylyltransferase . References reflist 1 cite journal author Warner AH, Beers PC, Huang FL date 1974 title Biosynthesis of the diguanosine nucleotides. I. Purification and properties of an enzyme from yolk platelets of brine shrimp embryos journal Can. J. Biochem. volume 52 pages 231&ndash 40 pmid 4208243 issue 3 enzyme stub Category EC 2.7.7 Category Enzymes of unknown structure ... more details
enzyme Name nucleoside triphosphate diphosphatase EC number 3.6.1.19 CAS number 9075 54 1 IUBMB EC number 3 6 1 19 GO code 0047429 image width caption In enzymology , a nucleoside triphosphate diphosphatase EC number 3.6.1.19 is an enzyme that catalysis catalyzes the chemical reaction a nucleoside triphosphate H sub 2 sub O math rightleftharpoons math a nucleotide diphosphate Thus, the two substrate biochemistry substrates of this enzyme are nucleoside triphosphate and water H sub 2 sub O , whereas its two product chemistry products are nucleotide and diphosphate . This enzyme belongs to the family of hydrolase s, specifically those acting on acid anhydrides in phosphorus containing anhydrides. The systematic name of this enzyme class is nucleoside triphosphate diphosphohydrolase . This enzyme is also called nucleoside triphosphate pyrophosphatase . This enzyme participates in purine metabolism and pyrimidine metabolism . Structural studies As of late 2007, 5 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1V7R , PDB link 2CAR , PDB link 2E5X , PDB link 2I5D , and PDB link 2J4E . References reflist 1 cite journal author Chern CJ, MacDonald AB, Morris AJ date 1969 title Purification and properties of a nucleoside triphosphate pyrophosphohydrolase from red cells of the rabbit journal J. Biol. Chem. volume 244 pages 5489&ndash 95 pmid 4310599 issue 20 hydrolase stub Category EC 3.6.1 Category Enzymes of known structure ... more details
Multiple issues expert subject August 2008 cleanup August 2008 orphan February 2009 enzyme Name nucleoside triphosphate hexose 1 phosphate nucleotidyltransferase EC number 2.7.7.28 CAS number 37278 26 5 IUBMB EC number 2 7 7 28 GO code 0047339 image width caption In enzymology , a nucleoside triphosphate aldose 1 phosphate nucleotidyltransferase EC number 2.7.7.28 is an enzyme that catalysis catalyzes the chemical reaction nucleoside triphosphate alpha D aldose 1 phosphate math rightleftharpoons math diphosphate NDP hexose Thus, the two substrate biochemistry substrates of this enzyme are nucleoside triphosphate and alpha D aldose 1 phosphate , whereas its two product chemistry products are diphosphate and NDP hexose . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing nucleotide groups nucleotidyltransferase s . The systematic name of this enzyme class is NTP alpha D aldose 1 phosphate nucleotidyltransferase . Other names in common use include NDP hexose pyrophosphorylase , hexose 1 phosphate nucleotidyltransferase , hexose nucleotidylating enzyme , nucleoside diphosphohexose pyrophosphorylase , hexose 1 phosphate guanylyltransferase , GTP alpha D hexose 1 phosphate guanylyltransferase , GDP hexose pyrophosphorylase , guanosine diphosphohexose pyrophosphorylase , nucleoside triphosphate hexose 1 phosphate nucleotidyltransferase , and NTP hexose 1 phosphate nucleotidyltransferase . References reflist 1 cite journal author Verachtert H, Rodriguez P, Bass ST, Hansen RG date 1966 title Purification and properties of guanosine diphosphate hexose pyrophosphorylase from mammalian tissues journal J. Biol. Chem. volume 241 pages 2007&ndash 13 pmid 5946626 issue 9 cite journal author Hansen RG, Verachtert H, Rodriguez P and Bass ST date 1966 title GDP hexose pyrophosphorylase from liver journal Methods Enzymol. volume 8 pages 269&ndash 271 doi 10.1016 0076 6879 66 08048 0 series Methods in Enzymology isbn 9780121818081 e ... more details
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