- Desmopressin
Ddavp, Stimate Drugs.com drugs.com monograph desmopressin acetate pregnancy AU B2 pregnancy US ... NFLWUMRGJYTJIN NXBWRCJVSA N Desmopressin trade names DDAVP , Stimate , Minirin is a chemical synthesis ... nasally, intravenously, or as a tablet. Doctors prescribe Desmopressin most frequently for treatment of diabetes insipidus , bedwetting or nocturia . Chemistry Desmopressin 1 desamino 8 small D small ... , a peptide containing nine amino acids. Compared to vasopressin, desmopressin s first amino acid ... than the levo form see stereochemistry . Mode of action Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to Arginine vasopressin receptor 2 V2 receptor ... of von Willebrand factor from endothelial cell s by acting on the V2 receptor. Desmopressin is degraded ... . Clinical uses Sleep Apnea Doctors prescribe desmopressin frequently for treatment. It is usually in the form of Desmopressin acetate, DDAVP. Patients taking DDAVP are 4.5 times more likely ... sleep apnea with desmopressin nasal sprays after two patients died and 59 other patients suffered seizures. The patients were using desmopressin when they developed Hyponatremia , an imbalance of the body ... said that desmopressin tablets could still be considered safe for Sleep Apnea treatment, as long as the patient was otherwise healthy. Patients must stop taking desmopressin if they become sick ... date April 2011 ref Coagulation disorders Desmopressin can be used to promote the release of von ... 2B. Diabetes insipidus Desmopressin is used in the treatment of neurogenic diabetes insipidus central ... Neuropeptidergics Category Hormonal agents cs Desmopresin da Desmopressin de Desmopressin es Desmopresina ... more details
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- Vasopressin analogue
Unreferenced stub auto yes date December 2009 Vasopressin analogues are chemicals similar in function but not necessarily similar in structure to vasopressin ADH , such as desmopressin . Desmopressin is administered as an oral spray to treat diseases where ADH is either not being produced in sufficient amounts, or vasopressin s receptor biochemistry receptor s are not being stimulated by the vasopressin. An example of desmopressin s use is for childhood bed wetting, where it is believed that children s circadian rhythms are not synchronized with normal light dark cycles, and consequentially the ADH surge normal children experience at night is not experienced in these children. Taking a desmopressin dose 30 45 minutes before sleeping results in concentrated urine production, and the urination reflex experienced when the bladder fills above a certain level is not triggered. Pituitary and hypothalamic hormones and analogues DEFAULTSORT Vasopressin Analogue Category Pharmacology 11 systemic hormonal drug stub ... more details
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- Antidiuretic
An antidiuretic is an Biological agent agent or drug that, administered to an organism , helps control body water balance by reducing urination , ref MeshName Antidiuretic Agents ref opposing diuretic diuresis . ref DorlandsDict one 000006007 antidiuretic ref Uses Antidiuretics are the drugs that reduce urine volume, particularly in diabetes insipidus DI which is their primary indication. Examples These are classified as Antidiuretic hormone s Vasopressin ADH Vasopressin , Desmopressin , Lypressin , Terlipressin Miscellaneous Chlorpropamide , Carbamazepine See also Diuretic References reflist Pituitary and hypothalamic hormones and analogues Category Drugs systemic hormonal drug stub id Antidiuretik jv Antidiuretik sr Antidiuretik ... more details
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- Fluid deprivation test
Diagnostic infobox Name PAGENAME Image Caption ICD10 ICD9 MeshID OPS301 OPS301 1 797 OtherCodes A fluid or water deprivation test is a medical test ref name urlcsiii26a cite web url http www1.indstate.edu thcme anderson Clinical csiii26a.html title csiii26a format work accessdate 2009 04 04 Dead link date October 2010 bot H3llBot ref which can be used to determine whether the patient has diabetes insipidus as opposed to other causes of polydipsia a condition of excessive thirst that causes an excessive intake of water . The patient is required, for a prolonged period, to forgo intake of water completely, to determine the cause of the thirst. This test measures changes in body weight, urine output, and urine composition when fluids are withheld. Sometimes measuring blood levels of ADH a synonym for vasopressin during this test is also necessary. If there is no change in the water loss despite fluid deprivation, desmopressin may be administered to distinguish between the two types of diabetes insipidus which are central & nephrogenic diabetes insipidus. The time of deprivation may vary from 4 to 18 hours. ref name Lavin2009 cite book author Norman Lavin title Manual of Endocrinology and Metabolism url http books.google.com books?id a Eg0vPb6o4C&pg PA67 accessdate 12 November 2010 date 1 April 2009 publisher Lippincott Williams & Wilkins isbn 9780781768863 pages 67 ref The serum osmolality and urine osmolality are both measured in the test. Interpretation The conditions can be distinguished in the following way class wikitable Condition Urine osmolality in mOsm kg, after fluid deprivation ref name GPnote http www.gpnotebook.co.uk simplepage.cfm?ID 1435828200&linkID 28152 Water deprivation and desmopressin test at GPnote ref After desmopressin ref name GPnote or vasopressin excessive intake of fluid primary polydipsia 800 800 a defect in Vasopressin ADH production central neurogenic diabetes insipidus 300 800 a defect in the kidneys response to Vasopressin ADH productio ... more details
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- Diabetes insipidus
time consuming to perform. ref name agabegi2nd To distinguish between the main forms, desmopressin stimulation is also used desmopressin can be taken by injection, a nasal spray, or a tablet. While taking desmopressin, a patient should drink fluids or water only when thirsty and not at other times, as this can lead to sudden fluid accumulation in the central nervous system. If desmopressin reduces ... responds normally. If the DI is due to renal pathology, desmopressin does not change either urine ... vasopressin secretion and increases urine output. Desmopressin is ineffective, and can lead ... 17308961 doi 10.1007 s11102 007 0006 1 ref Most cases of gestational DI can be treated with desmopressin. In rare cases, however, an abnormality in the thirst mechanism causes gestational DI, and desmopressin ... mortality. Treatment Central DI and gestational DI respond to desmopressin . Carbamazepine , an anticonvulsive ... pregnancies. In dipsogenic DI, desmopressin is not usually an option. Desmopressin will be ineffective ... more details
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- ATC code H01
ATC codes lead H 01 Pituitary and hypothalamic hormones and analogues vet add anchor H01A H01A Anterior pituitary lobe hormones and analogues anchor H01AA H01AA Adrenocorticotropic hormone H01AA01 Corticotropin H01AA02 Tetracosactide anchor H01AB H01AB Thyrotropin H01AB01 Thyrotropin anchor H01AC H01AC Somatropin and somatropin agonists H01AC01 Somatropin H01AC02 Somatrem H01AC03 Mecasermin H01AC04 Sermorelin H01AC05 Mecasermin rinfabate H01AC06 Tesamorelin anchor H01AX H01AX Other anterior pituitary lobe hormones and analogues H01AX01 Pegvisomant anchor H01B H01B Posterior pituitary lobe hormones anchor H01BA H01BA Vasopressin and analogues H01BA01 Vasopressin H01BA02 Desmopressin H01BA03 Lypressin H01BA04 Terlipressin H01BA05 Ornipressin H01BA06 Argipressin anchor H01BB H01BB Oxytocin and analogues H01BB01 Demoxytocin H01BB02 Oxytocin H01BB03 Carbetocin anchor H01C H01C Hypothalamic hormones anchor H01CA H01CA Gonadotropin releasing hormones H01CA01 Gonadorelin H01CA02 Nafarelin H01CA03 Histrelin QH01CA90 Buserelin QH01CA91 Fertirelin QH01CA92 Lecirelin QH01CA93 Deslorelin QH01CA94 Azagly nafarelin QH01CA95 Peforelin QH01CA96 Salmon gonadotropin releasing hormone analogue anchor H01CB H01CB Somatostatin and analogues H01CB01 Somatostatin H01CB02 Octreotide H01CB03 Lanreotide H01CB04 Vapreotide H01CB05 Pasireotide anchor H01CC H01CC Anti gonadotropin releasing hormones H01CC01 Ganirelix H01CC02 Cetrorelix References Reflist Pituitary and hypothalamic hormones and analogues Category ATC codes H01 ca Codi ATC H01 cs ATC k d H01 es Anexo C digo ATC H01 ko ATC H01 hu ATC H01 Hipof zis hormonok, hipotalamusz hormonok s anal gjaik pl ATC H01 ro Cod ATC H01 sv ATC kod H01 Hypofys och hypotalamushormoner samt analoger th ATC H01 ... more details
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- List of drugs: De
International Nonproprietary Name INN desmethylmoramide International Nonproprietary Name INN Desmopressin acetate Desmopressin Acetate desmopressin International Nonproprietary Name INN desmoteplase ... more details
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- List of drug interactions
dynamic list The following is a list of drug interaction interactions with various prescription drug prescription and over the counter drug s id toc class toc summary Contents MediaWiki Toc A A B B C C D D E E F F G G H H I I J J K K L L M M N N O O P P Q Q R R S S T T U U V V W W Y Y X X Z Z References References br NOTOC A class wikitable style background color DDDDDD text align center Generic name Potentiates Decreases Street drug s Food Pregnancy Breastfeeding Nursing Acetaminophen ref http www.mdadvice.com library drug drug1.html ref Paracetamol Isoniazid Alcohol Allopurinol ref http www.mdadvice.com library drug drug7.html ref Ampicillin , Azathioprine , Chlorpropamide , Ethacrynic acid , Furosemide , Furosemide , Indapamide , Mercaptopurine , Metolazone , Probenecid , Theophylline Cocaine Unknown Avoid Ambenonium ref http www.mdadvice.com library drug drug8.html ref Guanadrel , Guanethidine , Mecamylamine , Procainamide , Quinidine , Trimethaphan Cocaine Avoid Safe B class wikitable style background color DDDDDD text align center Generic name Potentiates Decreases Street drug s Food Pregnancy Breastfeeding Nursing Bacampicillin ref http www.mdadvice.com library drug drug65.html ref Beta adrenergic br Birth control pill s br Probenecid br Sodium benzoate Chloramphenicol br Erythromycin br Loperamide br Paromomycin br Tetracycline br Troleandomycin alcoholic beverages, acidic fruits or juices unknown avoid C class wikitable style background color DDDDDD text align center Generic name Potentiates Decreases Street drug s Food Pregnancy Breastfeeding Nursing Carbamazepine ref http www.mdadvice.com library drug drug94.html ref Barbiturate s br Benzodiazepine br Cimetidine br Clozapine br Desmopressin br Erythromycin br Ethinamate br Guanfacine br Isoniazid br Leucovorin br MAO Inhibitor s br Nicardipine br Nimodipine br Nizatidine br Propoxyphene br Sertraline br Tiopronin br Verapamil Anticoagulant s br Hydantoin anticonvulsants br Cisapride br Oral contraceptive ... more details
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- List of drugs: D-Dd
to desmopressin ... more details
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- List of medical abbreviations: D
MedAbbrev C E class wikitable sortable Sortable table scope col Abbreviation scope col Meaning D sub S sub diagnosis D5 5 Glucose dextrose D25 25 Glucose dextrose injections D4T stavudine D5W 5 Glucose dextrose in water Intravenous therapy IV fluids IV fluids for intravenous therapy d day s DA dopamine DAEC diffusely adherent Escherichia coli DAF decay accelerating factor DAI diffuse axonal injury DALY disability adjusted life year DBP diastolic blood pressure DBS deep brain stimulation D&C dilatation and curettage D C discharge br discontinue D&E dilation and evacuation DCBE Contrast medium Negative Contrast Media double contrast barium enema DCD donation after cardiac death DCCV direct current cardioversion DCIS ductal carcinoma in situ DCM dilated cardiomyopathy DD differential diagnosis DDAVP desmopressin acetate DDC zalcitabine DDD daily defined doses DDH developmental hip dysplasia DDI didanosine DDx differential diagnosis D&E Dilation and evacuation dilatation and evacuation DES diethylstilbestrol DEXA Dual energy X ray absorptiometry DH developmental history DHE dihydroergotamine DHEA S Dehydroepiandrosterone dehydroepiandrosterone sulphate DHF decompensated heart failure DHR dihydrorhodamine DHT dihydrotestosterone DI diabetes insipidus DIB dead in bed br difficulty in breathing DIC disseminated intravascular coagulation Di Di dichromatic diamnionic twins DIL drug induced lupus DILI drug induced liver injury DIP Interphalangeal joints distal interphalangeal joint DiPerTe diphtheria pertussis tetanus combined vaccination Dis dislocation Disch discharge DiTe diphtheria tetanus combined vaccination DIU death Uterus in utero stillbirth DJD degenerative joint disease osteoarthritis DKA diabetic ketoacidosis dl deciliter dL deciliter DLB Lewy body dementia DLCO diffusing capacity of the lung for carbon monoxide DLE disseminated lupus erythematosus systemic lupus erythematosus DM diabetes mellitus DMARD disease modifying antirheumatic drug DMD Duchenne muscular dy ... more details
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- Neurogenic diabetes insipidus
. Treatment The disorder is treated with vasopressin analogs such as Desmopressin . See also Fluid ... more details
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- Enuresis
be treated by increasing ADH levels. The hormone can be boosted by a synthetic version known as desmopressin ... desmopressin into their nostrils. Desmopressin is approved for use by children. Another medication ... more details
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- Heyde's syndrome
Angiodysplasia Symptomatic treatment can be given in the form of blood transfusion s. Desmopressin ... more details
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- Glanzmann's thrombasthenia
drugs such as tranexamic acid or Aminocaproic acid aminocaproic acid Amicar Desmopressin DDAVP ... more details
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- Cryoprecipitate
unless last reserve. Desmopressin ddAVP is first line, followed by factor concentrates. Hypofibrinogenaemia ... more details
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- Terlipressin
international terlipressin.html ref See also Desmopressin References Reflist Pituitary and hypothalamic ... more details
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- Primary polydipsia
See also Water intoxication Water deprivation and desmopressin test References reflist External ... more details
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- CSL Limited
factor IX that has been purified using monoclonal antibodies Stimate , a synthetic desmopressin ... , a synthetic desmopressin acetate nasal spray human lung Pulmonary Zemaira , freeze dried Human ... more details
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- CSL Behring
factor IX that has been purified using monoclonal antibodies Stimate , a synthetic desmopressin ... , a synthetic desmopressin acetate nasal spray Pulmonary Zemaira , freeze dried Human Alpha sub 1 ... more details
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- Tachyphylaxis
, also demonstrates tachyphylaxis. Desmopressin used in the treatment of von Willebrand disease ... more details
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- Nephrogenic diabetes insipidus
hydration. Desmopressin DDAVP can also be used if the patient is able to concentrate urine following ... more details
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- Nasal administration
sprays, in this case to avoid drug degradation after oral administration. The peptide analogue desmopressin ... more details
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- Hemostasis
of therapies, estrogen estrogen progesterone progesterone preparations, desmopressin desmopressin ... more details
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- Nocturnal enuresis
02 03 last Evans first Jonathan ref DDAVP desmopressin br Desmopressin tablets are a synthetic replacement .... Desmopressin is usually used in the form of desmopressin acetate, DDAVP. Patients taking DDAVP are 4.5 ... for that night with no cumulative effect. br US drug regulators have banned using desmopressin nasal sprays for treating bedwetting, but say that desmopressin pills are still considered a safe ... more details
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- Plateletpheresis
respond to therapy with desmopressin dDAVP . Transfusion is not necessarily required. However ... patients prophylactically but only when they are bleeding excessively, while also giving desmopressin ... more details
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