refimprove date May 2010 Infobox Disease Name Dextrocardia Image Situs inversus chest Nevit.jpg Caption Chest X ray of a person with dextrocardia situs inversus showing the cardiac apex facing the right ... eMedicineTopic MeshName DextroCardia MeshNumber C14.240.400.280 Dextrocardia is a congenital defect in which the heart is situated on the right side of the body. There are two main types of dextrocardiadextrocardia of embryonic arrest also known as isolated dextrocardia and dextrocardia situs inversus . Dextrocardia situs inversus is further divided. Dextrocardia of embryonic arrest In this form of dextrocardia, the heart is simply placed farther right in the thorax than is normal. It is commonly ... Museums issue 5 title On the differentiation of two forms of congenital dextrocardia author M. E ... ref Dextrocardia situs inversus Dextrocardia situs inversus refers to the heart being a mirror image ... term is Situs inversus dextrocardia situs inversus totalis . Dextrocardia is believed to occur in approximately ... A population based study of cardiac malformations and outcomes associated with dextrocardia journal ... than being seasonal. Although statistically people with dextrocardia situs inversus do not have any ... threatening if left unchecked. Diagnosis Medical diagnosis of the two forms of congenital dextrocardia can be made by ECG ref name AbbottMeakins or imaging. Technical dextrocardia Technical dextrocardia ... of dextrocardia is caused usually by the technician inadvertently swapping the limb leads on a 12 lead ... must be placed in reversed positions on a person with dextrocardia. In addition, when Defibrillation defibrillating someone with dextrocardia, the pads should be placed in reverse positions. citation ... RareDiseases 1827 Dextrocardia RareDiseases 6268 Dextrocardia with situs inversus Laterality Congenital ... system az Dekstrokardiya de Dextrokardie es Dextrocardia fa fr Dextrocardie it Destrocardia pl Dekstrokardia pt Dextrocardia ru sr ... more details
Infobox disease Name Stratton Parker Syndrome ICD10 none ICD9 none Image Image width Image caption DiseasesDB OMIM 185120 MedlinePlus eMedicineSubj eMedicineTopic eMedicine mult MeshID Stratton parker syndrome is a rare disorder characterized by short stature, wormian bones extra cranial bones , and dextrocardia displaced heart . ref name orphan cite web publisher Check Orphan title Short stature wormian bones dextrocardia accessdate 2011 09 27 url http checkorphan.com disease short stature wormian bones dextrocardia ref Other symptoms include dermatoglyphics , tooth deformities or missing teeth, abnormal kidney development, shortened limbs, mental retardation, undescended testes or cryptorchidism , and anal atresia . ref name orphan The condition was first described by Stratton and Parker in 1989, ref cite journal author Stratton RF, Parker MW title Growth hormone deficiency, wormian bones, dextrocardia, brachycamptodactyly, and other midline defects journal American Journal of Medical Genetics volume 32 issue 2 pages 169 73 year 1989 month February pmid 2564736 doi 10.1002 ajmg.1320320205 url accessdate 2011 09 27 ref and there have been only four reported cases worldwide. ref cite web publisher Endocrine Abstracts title Growth hormone deficiency and complex congenital abnormalities a further case of Stratton Parker syndrome? last1 Simmgen first1 M. last2 Bano first2 G. last3 Nussey first3 S. year 2006 volume 12 id P86 accessdate 2011 09 27 url http www.endocrine abstracts.org ea 0012 ea0012p86.htm ref Alternative names include Growth Hormone Deficiency with Wormian Bones, Cardiac Anomaly, and Brachycamptodactyly ref cite web publisher BioGraph title STRATTON PARKER SYNDROME accessdate 2011 09 27 url http www.biograph.be concept show C1861448 ref and Short stature wormian bones dextrocardia ref name orphan References Reflist DEFAULTSORT Stratton Parker Syndrome Category Rare diseases disease stub ... more details
Treacherous technician syndrome refers to a limb lead reversal that usually occurs due to the technical error of reversing the right and left arm electrodes. Treacherous technician syndrome has become more common as non experienced personnel replace electrocardiogram technician s. Treacherous technician syndrome is the most common cause of situs inversus or dextrocardia false positives. ref http www.emedicine.com radio topic639.htm eMedicine Situs Inversus Article by Annamaria Wilhelm Bot generated title ref Limb lead reversals LLRs remain clinically problematic. ref http www.ingentaconnect.com content bsc pace 2006 00000029 00000003 art00009 IngentaConnect Simple Diagnosis of Limb Lead Reversals by Predictable Changes in Bot generated title ref References references Glancy DL. Jones M. ECG of the month. Reversal of the arm leads or situs inversus with mirror image dextrocardia? Reversal of the limb leads and of the precordial leads. Case Reports. Journal Article Journal of the Louisiana State Medical Society. 159 2 63 5, 2007 Mar Apr. Rao PS. Dextrocardia systematic approach to differential diagnosis. Review 56 refs Journal Article. Review American Heart Journal. 102 3 Pt 1 389 403, 1981 Sep. Medicine Cardiovascular system Category Cardiology ... more details
Infobox Disease Name Levocardia Image Caption DiseasesDB ICD10 ICD10 Q 24 1 q 20 ICD9 ICD9 746.87 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D007979 Levocardia is a medical condition where the heart is on the correct side of the body the left , but the related structures are on the wrong side, either due to corrected transposition of the great vessels or to situs inversus . The term levocardia can also be used to indicate the absence of dextrocardia , and thus normal positioning of the heart part of situs solitus , normal positioning of the organs. However, this usage is less frequent. See also Laterality External links GPnotebook 80412663 Congenital malformations and deformations of circulatory system Category Congenital disorders of circulatory system disease stub ... more details
Unreferenced date December 2009 Infobox Anatomy Name Right heart Latin GraySubject GrayPage Image Diagram of the human heart cropped .svg Caption Anterior frontal view of the opened heart. White arrows indicate normal blood flow. Image2 Caption2 Map MapPos MapCaption Precursor System Artery Vein Nerve Lymph MeshName MeshNumber Dorlands DorlandsID Right heart is a term used to refer collectively to the right atrium and right ventricle of the heart occasionally, this term is intended to reference the right atrium, right ventricle, and the pulmonary trunk collectively. The right atrium receives de oxygen ated systemic circulation systemic blood from the superior vena cava superior and inferior vena cava inferior vena cavae . The blood is then pumped through the tricuspid valve into the right ventricle, which in turn pumps the blood through the pulmonary valve into the pulmonary artery . See also Left heart Dextrocardia Heart DEFAULTSORT Right Heart Category Cardiac anatomy ar bs Desno srce ta ... more details
Unreferenced date December 2009 Image Heart and lungs.jpg thumb right 230px The heart and lungs, from an older edition of Gray s Anatomy . Situs solitus is the normal position of thoracic and abdominal organs. Anatomy Anatomically , this means that the heart is on the left with the pulmonary right atrium atrium on the right and the left atrium systemic atrium on the left along with the cardiac apex. Right sided viscera organs are the liver , the gall bladder and a trilobed lung as well as the inferior vena cava , while left sided organs are the stomach , single spleen , a bilobed lung, and the aorta . Variants on the normal picture are relatively uncommon. Complete reversal of all organs is known as situs inversus , while reversal of some organs but not others is called situs ambiguus or heterotaxy. Isolated reversal of the heart with normally patterned viscera otherwise is termed dextrocardia . See also Situs inversus Situs ambiguus Chirality mathematics Laterality DEFAULTSORT Situs Solitus Category Thorax Category Abdomen ... more details
Wikify date September 2011 The Edinburgh Handedness Inventory is a measurement scale used to assess the dominance of a person s right or Left handedness left hand in everyday activities, sometime referred to as laterality . The inventory can be used by an observer assessing the person, or by a person self reporting hand use. The latter method tends to be less reliable due to a person over attributing tasks to the dominant hand. The Edinburgh Handedness Inventory was published in 1971 by R.C. Oldfield ref Oldfield, R.C. 1971 . The assessment and analysis of handedness The Edinburgh inventory. Neuropsychologia, 9, 97 113 ref and has been used in various scientific studies ref cite journal pmid 9638746 title NIH web site ref ref cite web url http brain.oxfordjournals.org cgi content full 123 12 2512 title Oxford journal accessdate 2009 04 08 ref as well as popular literature. ref cite book title A left handed Turn Around the World author David Wolman isbn 9780306814983 year 2006 ref See also Ambidexterity Cross dominance Dextrocardia Footedness Handedness Ocular dominance Situs inversus Laterality References reflist External links http www.brainmapping.org shared Edinburgh.php An online example of the tool authored by Mark Cohen , hosted at http www.brainmapping.org http www.brainmapping.org Category Motor skills Category Upper limb anatomy Category Handedness Category Chirality anatomy stub ... more details
For The Outer Limits 1963 TV series The Outer Limits television show episode Cold Hands, Warm Heart Cold Hands, Warm Heart is a young adult novel by Jill Wolfson . It was first published in 2009 by Henry Holt and Company ref http www.henryholtkids.com Publisher s website ref . This is Jill Wolfson s latest novel and it addresses subjects like life threatening illness, loss, and the gift of life through organ donation . Synopsis Fifteen year old Dani was born with her heart on the wrong side of her body, a condition called dextrocardia . Fourteen year old Amanda puts her heart and soul into competitive gymnastics. One girl lives a life of x rays, tests, and endless hospital visits while the other is on the fast track to the national championship. During a brilliant gymnastic routine, Amanda slips and a young life with so much potential comes to an end. With Amanda s death, Dani, in desperate need of a heart transplant , gets a second chance. References references DEFAULTSORT Cold Hands, Warm Heart Category 2009 novels Category American young adult novels 2000s ya novel stub ... more details
Wiktionary situ Wikisearchbox situ text2 situs The words situ and situs are Latin for site or location . They also have other meanings Situ means lake in Sundanese language Sundanese . Situ can refer to in situ , Latin phrase meaning on site or in place In situ compaction , a term for spray forming or spray casting In situ oxidation , in situ chemical oxidation ISCO is a technique to clean up some types of environmental contamination In situ polymerization , in polymer chemistry, means in the polymerization mixture Ductal carcinoma in situ , a form of cancer Lobular carcinoma in situ LCIS , a condition caused by unusual cells in the lobules of the breast rarely cancer Situ Babakan Lake, where water flows in from the Ciliwung River Situ Gintung , an artificial lake near to the town of Cirendeu People with the Chinese compound surname Situ Szeto Wah Situ Hua , Pinyin name of Szeto Wah, a chairman of The Hong Kong Alliance Situ Panchen , the 8th Tai Situ Rinpoche, an influential Tibetan De Situ Albanie , first of seven Scottish documents found in Poppleton Manuscript De Situ Britanniae , a fictional description of the peoples and places of ancient Britain Melanoma in situ , early stage where most melanomas are detected, before they become elevated Venus In Situ Explorer VISE , a mission to Venus proposed by NASA Tai Situ , or Tai Situpa, name of Chokyi Gyaltsen as first incarnation to bear the title Tai Situ Shakoor v Situ , a court case List of colossal sculpture in situ , roster of large sculptures created in place Lasik , laser assisted in situ keratomileusis , a type of refractive surgery for correcting myopia, hyperopia, etc. Situs can refer to Situs law , a legal term meaning site where a law applies Lex situs , refers to the law of the place in which property is situated Situs solitus , refers to the normal position of thoracic and abdominal organs Dextrocardia Situs Inversus , medical term for heart being a mirror image situated on the right side. Analysis S ... more details
is swapped to the right side of the thorax, it is known as situs inversus with dextrocardia ... inversus incompletus . Situs inversus with levocardia, or dextrocardia without situs inversus, present much higher rates of congenital defects than situs inversus with dextrocardia. Significance ... File Primary ciliary dyskinesia 10.jpg thumb Axial CT image showing dextrocardia and situs ... more details
of two forms of congenital dextrocardia ref cite journal journal Bulletin of the International Association of Medical Museums number 5 title On the differentiation of two forms of congenital dextrocardia ... more details
Refimprove date December 2009 The apex beat , also called the point of maximum impulse PMI , is the furthermost point outwards laterally and downwards inferiorly from the Human sternum sternum at which the cardiac impulse can be felt. The cardiac impulse is the result of the heart rotating, moving forward and striking against the chest wall during systole medicine systole . It is also known as the apical impulse . ref name BickleySzilagyi2008 cite book author1 Lynn S. Bickley author2 Peter G. Szilagyi title Bates guide to physical examination and history taking url http books.google.com books?id j272REejmWMC&pg PA357 accessdate 6 March 2011 date 1 December 2008 publisher Lippincott Williams & Wilkins isbn 9780781780582 pages 357 ref Identification The normal apex beat can be palpate d in the precordium left 5th intercostal space , at the point of intersection with the left midclavicular line . In children the apex beat occurs in the fourth rib interspace medial to the nipple. The apex beat may also be found at abnormal locations in many cases of dextrocardia , the apex beat may be felt on the right side. Interpretation div style float right gallery Image Apex beat.png Algorithm for classification of the apex beat characters gallery div Lateral and or inferior displacement of the apex beat usually indicates enlargement of the heart, called cardiomegaly . The apex beat may also be displaced by other conditions Pleural or pulmonary diseases Deformities of the chest wall or the thoracic vertebra Sometimes, the apex beat may not be palpable, either due to a thick chest wall, or conditions where the stroke volume is reduced such as during ventricular tachycardia or Shock circulatory shock . The character of the apex beat may provide vital diagnosis diagnostic clues A forceful impulse indicates pressure overload in the heart as might occur in hypertension An uncoordinated dyskinesia dyskinetic apex beat involving a larger area than normal indicates heart ventricle ventricu ... more details
Infobox Disease Name Marden Walker syndrome Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 248700 MedlinePlus eMedicineSubj eMedicineTopic MeshID Marden Walker syndrome MWS is a rare autosome autosomal dominance genetics recessive congenital disorder . ref name omim OMIM 248700 ref ref name mwsar cite pmid 7677143 ref It is characterized by blepharophimosis , microcephaly , micrognathia , multiple joint contracture s, arachnodactyly , camptodactyly , kyphoscoliosis , and delayed motor development and is often associated with cystic dysplastic kidney s, dextrocardia , Dandy Walker syndrome Malformation Dandy Walker malformation , and Agenesis of the corpus callosum agenesis of corpus callosum . ref name badano2006 cite journal author Badano JL, Mitsuma N, Beales PL, Katsanis N title The ciliopathies an emerging class of human genetic disorders journal Annu Rev Genomics Hum Genet volume 7 issue pages 125 148 year 2006 pmid 16722803 doi 10.1146 annurev.genom.7.080505.115610 url http arjournals.annualreviews.org doi abs 10.1146 annurev.genom.7.080505.115610 ref Pathophysiology Though the pathomechanism of Marden Walker syndrome is unknown, it may be caused by a genetic defect which manifests as a ciliopathy dysfunctional molecular mechanism in the primary cilia structures of the Cell biology cell . These organelle s are present in many cellular types throughout the human body. The cilia defects adversely affect numerous critical developmental signaling pathways essential to cellular development ref name badano2006 . Genetics Image Autorecessive.jpg thumb right Marden Walker syndrome has an autosomal recessive pattern of heredity inheritance . MWS is inherited in an autosomal recessive manner. ref name mwsar This means the defective gene responsible for the disorder is located on an autosome , and two copies of the defective gene one inherited from each parent are required in order to be born with the disorder. The parents of an individual with an autosomal recessive diso ... more details
Infobox artist bgcolour 6495ED name Dick Ket image Self portrait of Dick Ket.jpg imagesize 200px caption Self portrait of Dick Ket birth name birth date birth date 1902 10 10 birth place death date death date and age 1940 9 15 1902 10 10 death place nationality Netherlands Dutch field Painting , Magic realism , Still life , Self portrait training movement works patrons influenced by Neue Sachlichkeit influenced awards Dick Ket October 10, 1902 &ndash September 15, 1940 was a Netherlands Dutch Magic realism magic realist painter noted for his still life s and self portrait s. Biography Born in Den Helder , Ket spent his childhood in Hoorn and then Ede, Netherlands Ede before attending the Kunstoefening in Arnhem from 1922 to 1925. Born with a serious heart defect believed to be tetralogy of Fallot with dextrocardia , ref http www.ncbi.nlm.nih.gov sites entrez?cmd Retrieve&db PubMed&list uids 8985496&dopt AbstractPlus www.pubmed.gov, accessed September 15, 2007 ref ref name Lock Lock, Last, & Dunea 2001, p. 66. ref he was prevented from traveling by debilitating weakness as well as by phobias, and lived secluded in his parents house in Bennekom after 1930. Exposed to modern art mainly through reproductions, he concentrated on painting still lifes and self portraits. His health worsened in his last decade, leading to his early death in Bennekom in 1940. Works While Ket s earliest paintings are impressionism impressionistic in style, he was influenced decisively by the art of the Neue Sachlichkeit in 1929, and thereafter painted in a magic realist style. His meticulously composed and rendered still lifes feature favorite objects such as bottles, an empty bowl, eggs, and musical instruments. Ket juxtaposed these objects in angular arrangements, seen from a high vantage point, their cast shadows creating emphatic diagonals. These compositions reveal the influence of cubism as filtered through the posters of Cassandre , which are frequently depicted in Ket s paintings. Ano ... more details
Infobox disease Name 18p Image Alt Caption DiseasesDB ICD10 ICD9 ICDO OMIM 146390 MedlinePlus eMedicineSubj eMedicineTopic MeshID 18p is a genetic condition caused by a deletion of all or part of the short arm the p arm of chromosome 18. It occurs in about 1 of every 40,000 births. Nomenclature The preferred terminology for this condition is 18p . In the past, it has been referred to as partial monosomy 18p and, rarely, as de Grouchy syndrome, type 1 . Genetic Basis 18p describes a deletion of the short arm of chromosome 18. About half of the people with deletions have a breakpoint at the centromere . Diagnosis Suspicion of a chromosome abnormality is typically raised due to the presence of developmental delay developmental delays or birth defects . Diagnosis of 18p is usually made via a blood sample. A routine chromosome analysis, or karyotype , is usually used to make the initial diagnosis, although it may also be made by microarray analysis . Increasingly, microarray analysis is also being used to clarify breakpoints. Prenatal diagnosis is possible via amniocentesis of chorionic villus sampling . Clinical Description 18p causes a wide range of medical and developmental concerns. There is significant variation in severity. This variation is due to the variability of the deletion size and breakpoints. Congenital Anomalies About 10 15 of individuals with 18p have holoprosencephaly . Approximately 10 of people with 18p have a heart defect congenital heart anomaly . There does not appear to be a specific type of heart defect associated with a deletion of the short arm of chromosome 18. Septal defect Septal defects , tetralogy of Fallot , dextrocardia , and coarctation of the aorta have all been reported in infants with 18p . Neurologic Hypotonia is frequently seen in the 18p population. Seizures , though uncommon, have been reported in people with 18p . Dystonia has also been diagnosed in a small minority of young adults with 18p . Also, tethered cord has been reporte ... more details
year 1997 month July pmid 9240585 doi url issn ref Pulmonary hypoplasia is associated with Dextrocardiadextrocardia of embryonic arrest in that both conditions can result from early errors of development ... hypoplasia was part of the differential diagnosis of dextrocardia . ref name AbbottMeakins cite journal ... of two forms of congenital dextrocardia author M. E. Abbott and J. C. Meakins pages 134 138 ... more details
Infobox disease Name Diffuse idiopathic skeletal hyperostosis Image Alt Caption DiseasesDB 4932 ICD10 ICD9 ICDO OMIM 106400 MedlinePlus eMedicineSubj article eMedicineTopic 1258514 eMedicine mult eMedicine2 article 388973 MeshID GeneReviewsID GeneReviewsName Diffuse idiopathic skeletal hyperostosis DISH is a spondyloarthropathy also known as Forestier s disease and ankylosing hyperostosis. It is a noninflammatory disease, with the principal manifestation being calcification and ossification of spinal ligaments and the regions where tendons and ligaments attach to bone entheses . The whole spine may be involved, and bony ankylosis occurs, although the disc spaces and facet joints remain unaffected. In advanced stages, the disease may look like melted candle wax. ref Waldron, T. Paleopathology . Cambridge University Press, 2009, p. 73. ref The calcification and ossification is most common in the right side of the spine. In people with dextrocardia and situs inversus this calcification occurs on the left side, which might indicate a role of the mechanical pulsation of the aorta, at least as an aggravating cause. ref Forestier, J., Lagier, R. Ankylosing hyperostosis of the spine. Clin. Orthop. 1971 74 65 ref Etiology The exact cause is unknown. Mechanical factors, dietary and long term use of some antidepressants may be of significance. There is a correlation between these factors but not a cause or effect. The distinctive radiological feature of DISH is the continuous linear calcification along the antero medial aspect of the thoracic spine. The disease is usually found in people in their 60 s and above, and is extremely rare in people in their 40 s and 30 s. The disease can spread to any joint of the body, affecting the neck, shoulders, ribs, hips, pelvis, knees, ankles, and hands. The disease is not fatal , however some associated complications can lead to death. Complications include paralysis , dysphagia the inability to swallow , and pulmonary infections. Although ... more details
Refimprove date February 2008 James Bond Character image Image DrJuliusNo.jpg 200px bgcolor 000 fgcolor fff name Dr. Julius No portrayed Joseph Wiseman br Carlos Alazraqui voice, GoldenEye Rogue Agent gender Male age early 40 s affiliation Soviet Union novel br SPECTRE film br Independent OCTOPUS fictional organisation OCTOPUS video games status Deceased role List of James Bond s villains Villain Dr. Julius No is a fictional character and the main antagonist in the James Bond Dr. No film film and Dr. No novel novel Dr. No . He was the first James Bond villain in the film series, in which he was portrayed by actor Joseph Wiseman . Novel biography Although the film and novel are similar in Plot narrative plot , the backgrounds for Julius No carry certain differences. An individual of Chinese people Chinese Germans German cultural heritage, the novel s Dr. No was born in Peking to a German Methodist missionary and a Chinese girl, but was raised by his aunt. When older, he went to Shanghai , where he became involved with the Tong gang Tongs , a Chinese crime syndicate. Later he was smuggled to the United States and settled in New York City , where he became a clerk and eventually Treasurer for a Tong in America, called the Hip Sing Association Hip Sings . In the late 1920s, a mob war broke out in New York, forcing the police to crack down on them. No stole a million dollars in gold from the Tongs and disappeared. But the Tongs tracked him down and torture d him to find the location of the gold. When No did not tell them, the Tongs cut off his hands, shot him through the left side of the chest and left him for dead. No survived, due to a condition called dextrocardia , in which his heart was on the right side of the body. No spent a long time in hospital, then enrolled in medical school in Milwaukee, Wisconsin . It is unclear if he completed his studies, but he adopted the title of Doctor and changed his name his birth name is unknown to Julius No, symbolic of his reject ... more details
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