Drugclassbox Name Diuretic Image Renal Diuretics.gif Alt Caption This illustration shows where some types ... C03 MeshID Drugs.com Consumer Reports medicinenet rxlist A diuretic provides a means of forced ... Oct 17, 2011 ref The antihypertensive actions of some diuretics thiazide s and loop diuretic s in particular are independent of their diuretic effect. That is, the reduction in blood pressure is not due ... than most other diuretics. Types High ceiling loop diuretic High ceiling diuretics are diuretics ... calcium sparing diuretic is sometimes used to identify agents that result in a relatively low ... is much smaller than the increase associated with other diuretic classes. ref name isbn0 ..., is a sugar that can behave as an osmotic diuretic. Unlike mannitol, glucose is commonly found ... ceiling diuretics The term low ceiling diuretic is used to indicate that a diuretic has a rapidly ..., there are certain classes of diuretic which usually fall into this category, such as the thiazide ... bgcolor eeeeee Loop diuretic s bumetanide , ref name boron875 ethacrynic acid , ref name boron875 ... thick ascending limb bgcolor eeeeee Osmotic diuretic s glucose especially in uncontrolled diabetes ... descending limb bgcolor eeeeee Potassium sparing diuretic s amiloride , spironolactone , triamterene ... Diuretics Symptoms Hypovolemia loop diuretic s ref name boron875 thiazide s ref name boron875 lassitude ... boron875 hypokalemia acetazolamide s ref name boron875 loop diuretic s ref name boron875 thiazide ... name boron875 coma ref name boron875 metabolic alkalosis loop diuretic s ref name boron875 thiazide ... diuretic s ref name boron875 gout ref name boron875 See also antidiuretic References reflist 2 External links http cvpharmacology.com diuretic diuretics.htm Diagram at cvpharmacology.com Diuretics ... pam Diuretic lt Diuretikai hu Vizelethajt gy gyszerek mk nl Diureticum ja no Diuretikum nn Urindrivande l kjemiddel pl Leki moczop dne pt Diur tico ro Diuretic ru simple Diuretic ... more details
in combination with adequate rehydration. ref name AMH2004 Loop diuretic resistance Renal insufficiency .... Simultaneous treatment with a thiazide diuretic such as hydrochlorothiazide to inhibit sodium reabsorption ... reflist External links http www.fpnotebook.com cv pharm lpdrtc.htm Loop Diuretic , from the Family Practice Notebook MeshName Loop Diuretics Diuretics DEFAULTSORT Loop Diuretic Category Loop diuretics ... more details
Image Mersal.png thumb The structure of mersalyl acid Mercurial diuretics are a form of renal diuretic ref name pmid13174657 cite journal author DALE RA, SANDERSON PH title THE MODE OF ACTION OF A MERCURIAL DIURETIC IN MAN journal J. Clin. Invest. volume 33 issue 7 pages 1008 14 year 1954 month July pmid 13174657 pmc 438535 doi 10.1172 JCI102967 ref containing mercury. Although previously widely used, they have largely been superseded by safer diuretics such as thiazide s, and are hardly used anymore. History and mechanism Inorganic Mercury element mercury compounds, such as mercury I chloride calomel , were found to have diuretic properties when they were used to treat syphilis . ref name pmid11561230 cite journal format dead link date July 2010 author Ventura HO, Mehra MR, Young JB title Treatment of heart failure according to William Stokes the enchanted mercury journal J. Card. Fail. volume 7 issue 3 pages 277 82 year 2001 month September pmid 11561230 doi 10.1054 jcaf.2001.26564 url http linkinghub.elsevier.com retrieve pii S1071 9164 01 28406 1 ref Proposed use of these compounds date back at least to the 16th century, shortly after the beginning of the syphilis epidemic in 1497 following Colombus return to Europe. ref name pmid9185118 cite journal author Eknoyan G title A history of edema and its management journal Kidney Int. Suppl. volume 59 issue pages S118 26 year 1997 month June pmid 9185118 doi url ref Mercurial diuretics cause diuresis by reducing the reabsorption sodium in the ascending loop of Henle , thus causing more water being delivered to the distal convoluted tubule . Unfortunately, earlier physicians misconstrued hallmark symptoms of mercury poisoning such as excessive salivation as signs of mercury s efficacy, including up until the early 1960s when the use of mercurial diuretics were halted in medicine. Side effects Due to the idiosyncratic nature ... kidney by a mercurial diuretic meralluride journal Br J Pharmacol Chemother volume 20 issue 2 pages ... more details
An osmotic diuretic is a type of diuretic that inhibits reabsorption of water and Na. They are pharmacologically inert substances that are given intravenously. They increase the osmolarity of blood and renal filtrate. ref DorlandsDict three 000031887 osmotic diuretic ref Two examples are mannitol ref name urlMannitol cite web url http www2.massgeneral.org pharmacy ICU 20Guidelines mannitol.htm title Mannitol work accessdate 2008 12 20 ref and isosorbide . In the nephron , osmotic diuretics act at the portions of the nephron that are water permeable. ref name isbn0 07 139930 5 cite book author Trevor, Anthony J. Katzung, Bertram G. title Pharmacology publisher Lange Medical Books McGraw Hill, Medical Publishing Division location New York year 2003 pages 46 isbn 0 07 139930 5 oclc doi accessdate ref Osmotic diuretics works by expanding extracellular fluid and plasma volume, therefore increasing blood flow to the kidney . This washes out the cortical medullary gradient in the kidney. This stops the loop of Henle from concentrating urine, which usually uses the high osmotic and solute gradient to transport solutes and water. These agents can also act at other parts of the body. For example, they can be used to reduce intracranial ref name pmid17297315 cite journal author Sakowitz OW, Stover JF, Sarrafzadeh AS, Unterberg AW, Kiening KL title Effects of mannitol bolus administration on intracranial pressure, cerebral extracellular metabolites, and tissue oxygenation in severely head injured patients journal J Trauma volume 62 issue 2 pages 292 8 year 2007 month February pmid 17297315 doi 10.1097 01.ta.0000203560.03937.2d url http meta.wkhealth.com pt pt core template journal lwwgateway media landingpage.htm?an 00005373 200702000 00004 ref and intra ocular pressure. Physiological working of osmotic diuretics The renal proximal tubule is the primary site of action of osmotic diuretics. Normally, water molecules follow Na sup sup out of the proximal tubule, resulting in Na sup ... more details
A thiazide like diuretic is a Sulfonamide medicine sulfonamide diuretic that has similar physiological properties to a thiazide diuretic, but doesn t have the chemical properties of a thiazide, lacking the benzothiadiazine molecular structure. Examples include chlorthalidone and metolazone . Some, such as indapamide are considered thiazide like diuretics, but don t necessarily have the same mechanism. ref MeshName Indapamide ref References Reflist Diuretics Category Diuretics Cardiovascular drug stub ... more details
Insect diuretic hormones are hormone s that regulate water balance through diuretic action. The insect excretory system , responsible for regulating water balance in the insect, comprises the Malpighian tubules and the hindgut the ileum and rectum . Malpighian tubules secrete primary urine , most of which ... the fluid is excreted. Excretion is under the control of diuretic and anti diuretic factors, or hormones ... certain criteria. While there is evidence that some diuretic and antidiuretic factors are indeed ... been known for many years that insects possess diuretic and antidiuretic factors, but it has only .... Antidiuretic factors are less well studied than diuretic factors. They act either on the Malpighian ... insect for which both diuretic and antidiuretic hormones acting directly on tubules have been isolated is a beetle, the mealworm Tenebrio molitor Tenebrionidae . Functions of diuretic and antidiuretic ..., clearance of toxic wastes and restricting metabolite loss Coast et al., 2002 . The effects of diuretic ... easy to perform, many peptides are tested using this method. As a result, the effects of diuretic peptides ... is not investigated. There are three main families of diuretic hormones the corticotropin releasing ..., turned out to be the first example of a whole new family of insect diuretic peptides the calcitonin ... . It appears that all insects possess diuretic factors from two or more families, indicating that fluid ... of water, indicating that diuretic hormones may not always effect diuresis per se Nicolson, 1991 ... of the species name. For example, a 37 residue diuretic peptide from Tenebrio molitor will be named Tenmo DH37. References Coast G.M., Orchard, I., Phillips, J.E. and Schooley, D.A. 2002. Insect Diuretic ..., Schegg, K.M., Zhang, J., Tobe, S.S., Coast, G.M., Schooley, D.A., 2000. Cockroach diuretic hormones ... of the USA 97 6469 6474. Holtzhausen, W.D. and Nicolson, S.W. 2007. Beetle diuretic peptides ..., S.W. 1991. Diuresis or clearance is there a physiological role for the diuretic hormone of the desert ... more details
drugs with diuretic effects that decrease renal excretion of potassium. ref name Interaction ACEi ... in aldosterone release, which causes potassium sparing diuretic like effects similar to those ... more details
Froop or froops may refer to Froop, a German brand of fruit yogurt made by M ller company Froop, a diuretic containing furosemide Froops, fruit flavored hard candies made by the American Candy Company disambig ... more details
The molecular formula C sub 14 sub H sub 12 sub ClNO sub 2 sub molar mass 261.70 g mol may refer to Cicletanine , a furopyridine low ceiling diuretic drug, usually used in the treatment of hypertension Tolfenamic acid , a non steroidal anti inflammatory drug used to treat the symptoms of migraine MolFormDisambig ... more details
Chlormerodrin is a diuretic that was once used to treat patients with heart failure , but is no longer used in the United States. ref http www.nlm.nih.gov medlineplus ency article 002494.htm MedlinePlus Chlormerodrin overdose Update Date 1 15 2010. Updated by Jacob L. Heller. Also reviewed by David Zieve ref References reflist Category Diuretics medicine stub ... more details
An antidiuretic is an Biological agent agent or drug that, administered to an organism , helps control body water balance by reducing urination , ref MeshName Antidiuretic Agents ref opposing diuretic diuresis . ref DorlandsDict one 000006007 antidiuretic ref Uses Antidiuretics are the drugs that reduce urine volume, particularly in diabetes insipidus DI which is their primary indication. Examples These are classified as Antidiuretic hormone s Vasopressin ADH Vasopressin , Desmopressin , Lypressin , Terlipressin Miscellaneous Chlorpropamide , Carbamazepine See also Diuretic References reflist Pituitary and hypothalamic hormones and analogues Category Drugs systemic hormonal drug stub id Antidiuretik jv Antidiuretik sr Antidiuretik ... more details
Image Potassium sparing diuretics2.svg thumb Skeletal formula e of the aldosterone antagonists Aldosterone antagonist refers to diuretic drugs which receptor antagonist antagonize the action of aldosterone at mineralocorticoid receptor s. This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure . Spironolactone , the first member of the class, is also used in the management of hyperaldosteronism including Conn s syndrome and female hirsutism . Mechanism of Action Aldosterone antagonists are, as the name suggests, receptor antagonist s at the mineralocorticoid receptor . Antagonism of these receptors inhibits sodium resorption in the collecting duct of the nephron in the kidneys. This interferes with sodium potassium exchange, reducing urinary potassium excretion and weakly increasing water excretion diuresis . ref Rossi S, editor. Australian Medicines Handbook 2006. Adelaide Australian Medicines Handbook 2006. ref In congestive heart failure , they are used in addition to other drugs for additive diuretic effect, which reduces edema and the heart cardiac workload. Examples Members of this class in clinical use include Spironolactone Eplerenone more specific than spironolactone on target, but also more expensive Canrenone canrenoate potassium Prorenone prorenoate potassium Mexrenone mexrenoate potassium See also Potassium sparing diuretic ATC code C03 C03DA Aldosterone antagonists References references External links MeshName Aldosterone Antagonists MeshPharmaList 82000451 Hormone antagonists Diuretics Category Aldosterone antagonists Category Potassium sparing diuretics Category Steroids es Antagonista de la aldosterona pl Blokery receptora aldosteronowego ... more details
Unreferenced stub auto yes date December 2009 Orphan date December 2009 Tenoretic is a combination of two drugs prescribed for hypertension atenolol and chlorthalidone . Atenolol is a cardio selective beta blocker . Chlorthalidone is a diuretic . Tenoretic is not indicated for the initial treatment of hypertension but combines two effective drugs in a convenient once a day dosage for individuals who have been prescribed atenolol and chlorthalidone. Category Beta blockers Category Thiazides Category Drug brand names Antihypertensive stub ... more details
Unreferenced stub auto yes date December 2009 Natriuresis is the process of excretion of sodium in the urine via action of the kidney s. Natriuresis is promoted more sodium is excreted by Brain natriuretic peptide Brain and Atrial natriuretic peptide s, and it is inhibited sodium is conserved by chemicals such as aldosterone . Natriuresis lowers the concentration of sodium in the blood and also tends to lower blood volume because osmosis osmotic forces make water follow sodium out of the body s systemic circulation blood circulation and into the urine. Many diuretic medications drug s take advantage of this mechanism to treat medical conditions like hypernatremia and hypertension . Excess natriuresis can be caused by Medullary cystic disease Bartter syndrome Diuretic phase of acute tubular necrosis Some diuretics Primary renal diseases Congenital adrenal hyperplasia Syndrome of inappropriate antidiuretic hormone hypersecretion Renal physiology Category Renal physiology Biology stub ... more details
Drugbox verifiedrevid 424996356 Combo data type combo component1 triamterene class1 antikaliuretic drug potassium sparing diuretic component2 hydrochlorothiazide class2 diuretic antihypertensive drug Clinical data tradename Drugs.com drugs.com CDI dyazide MedlinePlus a601125 pregnancy AU A B1 B2 B3 C D X pregnancy US C pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA OTC, Rx only, Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US Rx only legal status routes of administration Oral Identifiers CAS number ATCvet ATC prefix none if uncategorised ATC suffix PubChem DrugBank Ref drugbankcite correct drugbank DrugBank Chemical data Dyazide is the brand name for a drug marketed by GlaxoSmithKline used to treat hypertension high blood pressure and edema water retention . Dyazide is a combination of triamterene and hydrochlorothiazide . This combination is in a class of medications called diuretic s or water pills , and causes the kidney s to get rid of the body s unneeded water and sodium through the urine . ref http www.nlm.nih.gov medlineplus druginfo meds a601125.html Triamterene and Hydrochlorothiazide . MedlinePlus. United States National Library of Medicine U.S. National Library of Medicine . National Institutes of Health . September 1, 2008. ref References reflist External links official http www.gsk.com products prescription medicines dyazide.htm http us.gsk.com products assets us dyazide.pdf Dyazide Prescribing Information GlaxoSmithKline cardiovascular drug stub Category GlaxoSmithKline Category Combination drugs ... more details
Drugbox Verifiedfields changed verifiedrevid 447991522 Combo data type combo component1 Amiloride class1 Potassium sparing diuretic component2 Furosemide class2 Loop diuretic Clinical data tradename Drugs.com drugs.com international co amilofruse pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU Unscheduled S2 S3 S4 S5 S6 S7 S8 S9 legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK POM legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Oral Identifiers CAS number Ref cascite correct ?? CAS number ATC prefix C03 ATC suffix EB01 PubChem DrugBank Ref drugbankcite correct drugbank DrugBank ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID NA Chemical data Co amilofruse British Approved Name BAN is a non wikt proprietary proprietary name used to denote a British Approved Name Combination preparations combination of amiloride and the formerly named frusemide now the International Nonproprietary Name INN termed furosemide . Co amilofruse in the treatment of fluid retention oedema , either in the legs peripheral edema or on the lungs pulmonary oedema . The stronger furosemide loop diuretic has a tendency to cause low potassium levels hypokalaemia that may be prevented by the Potassium sparing diuretics potassium sparing effects of amiloride. Formulation Two strengths of co amilofruse are available 2.5 mg amiloride with 20 mg furosemide, BAN of Co amilofruse 2.5 20 brand name Frumil LS 5 mg amiloride with 40 mg furosemide, BAN of Co amilofruse 5 4 0 brand name Frumil References British National Formulary 2004 Category Loop diuretics Category Potassium sparing diuretics Category Combination drugs cardiovascular drug stub ... more details
Drugbox verifiedrevid 447439314 Combo data type combo component1 Lisinopril class1 ACE inhibitor component2 Hydrochlorothiazide class2 Thiazide diuretic Clinical data tradename MedlinePlus a601070 pregnancy AU A B1 B2 B3 C D X pregnancy US D pregnancy category legal AU Unscheduled S2 S3 S4 S5 S6 S7 S8 S9 legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL P POM CD Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status Rx only routes of administration Oral Identifiers ATC prefix C09 ATC suffix BA03 Chemical data Lisinopril hydrochlorothiazide trade name Prinzide by Merck & Co. , Zestoretic by AstraZeneca , and many others is a combination of the drugs lisinopril , an ACE inhibitor , and hydrochlorothiazide , a diuretic . It is used to control hypertension . References Drugs.com http www.drugs.com mtm prinzide.html Prinzide Drugs.com http www.drugs.com zestoretic.html Zestoretic Agents acting on the renin angiotensin system Category Antihypertensive agents Category Combination drugs Antihypertensive stub ... more details
italic title Taxobox name Andean Horsetail image Equisetum bogotense Kunth.jpg image caption Andean horsetail regnum Plant ae divisio Pteridophyta classis Equisetopsida ordo Equisetales familia Equisetaceae genus Equisetum species E. bogotense binomial Equisetum bogotense binomial authority Kunth The Andean Horsetail Equisetum bogotense is a herbaceous perennial that reproduces through spores. It has thicker less bushy whorled branches, and a silica rich rhizomatous stem, which roots grow out of, under ground. This stem is a dull dark brown color with glabrous growth aside from the sheathed segments. The plant has a history as a traditional herbal remedy, and a study of its diuretic effects on humans showed significant increases in urinary sodium , potasium , and chloride . Human and animal trials of indicate that E. bogotense has high efficacy as a diuretic. ref http www.ncbi.nlm.nih.gov pubmed 17804183 Herbal medicines as diuretics A review of the scientific evidence ref It is used in several modern herbal supplements. ref http www.fda.gov ohrms dockets dailys 00 Jul00 072000 rpt0071.pdf ref References reflist External links http florawww.eeb.uconn.edu acc num 200600019.html binomial http members.eunet.at m.matus Equisetum bogotense.html basic information on the Andean Horsetail. Category Equisetum bogotense Category Fern species fern stub es Equisetum bogotense qu Uchuy kawallu chupa ... more details
Drugbox IUPAC name 6 chloro 2 cyclohexyl 3 oxo 2,3 dihydro 1 H isoindole 5 sulfonamide image Clorexolone.png Clinical data tradename pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CAS number 2127 01 7 ATC prefix C03 ATC suffix BA12 PubChem 16473 DrugBank ChemSpiderID 15615 UNII Ref fdacite correct FDA UNII Q2PLT3FS05 KEGG D01436 Chemical data C 14 H 17 Cl 1 N 2 O 3 S 1 molecular weight 328.814 g mol smiles O S O c1cc2C O N Cc2cc1Cl C3CCCCC3 N InChI 1 C14H17ClN2O3S c15 12 6 9 8 17 10 4 2 1 3 5 10 14 18 11 9 7 13 12 21 16,19 20 h6 7,10H,1 5,8H2, H2,16,19,20 InChIKey VPMWFZKOWULPGT UHFFFAOYAK Clorexolone is a diuretic Low ceiling diuretics low ceiling sulfonamide medicine sulfonamide diuretic . Diuretics Category Diuretics Category Sulfonamides Category Isoindoles Category Lactams Category Organochlorides cardiovascular drug stub ... more details
Drugbox IUPAC name ethyl 2 Z 3 methyl 4 oxo 5 piperidin 1 yl 1,3 thiazolidin 2 ylidene ethanoate image Etozolin.png Clinical data tradename pregnancy category legal status Rx only routes of administration ? Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number 73 09 6 ATC prefix C03 ATC suffix CX01 PubChem 5743585 ChemSpiderID 4675409 Chemical data C 13 H 20 N 20 O 3 S 1 molecular weight 284.37 g mol smiles O C OCC C C1 SC C O N1C N2CCCCC2 Etozoline Diulozin , Elkapin , Etopinil is a loop diuretic used in Europe . ref name isbn3 88763 075 0 cite book author Swiss Pharmaceutical Society title Index Nominum 2000 International Drug Directory Book with CD ROM publisher Medpharm Scientific Publishers location Boca Raton year 2000 pages isbn 3 88763 075 0 oclc doi accessdate ref ref name pmid3525089 cite journal author Lant A title Diuretic drugs. Progress in clinical pharmacology journal Drugs volume 31 Suppl 4 issue pages 40 55 year 1986 pmid 3525089 doi url http content.wkhealth.com linkback openurl?issn 0012 6667&volume 31&issue &spage 40 ref Synthesis Image Ozolinone.png 450px See also Ozolinone References Reflist Diuretics Category Diuretics Category Piperidines Category Thiazolidines Category Ethyl esters Category Lactams ... more details
Drugbox verifiedrevid 408836777 Combo data type combo component1 Telmisartan class1 Angiotensin II receptor antagonist component2 Hydrochlorothiazide class2 Thiazide diuretic Clinical data tradename MedlinePlus a611031 licence EU EMEA requires brand name licence US pregnancy AU D pregnancy US D pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US legal status Rx dependency liability routes of administration Mouth Oral Identifiers CAS number ATC prefix C09 ATC suffix DA07 PubChem 216293 KEGG Ref keggcite correct kegg KEGG D09219 Chemical data Telmisartan hydrochlorothiazide International Nonproprietary Name INNs , trade name Micardis HCT is an antihypertensive pharmaceutical drug drug combination of an angiotensin II receptor antagonist with hydrochlorothiazide, ref Drugs.com http www.drugs.com mtm micardis hct.html Micardis HCT ref the commonest diuretic to be combined with other blood pressure lowering substances. References reflist Agents acting on the renin angiotensin system Category Combination drugs Category Angiotensin II receptor antagonists cardiovascular drug stub ... more details
Drugbox verifiedrevid 412259800 Combo data type combo component1 Valsartan class1 Angiotensin II receptor antagonist component2 Hydrochlorothiazide class2 Thiazide diuretic Clinical data tradename MedlinePlus a682571 licence EU EMEA requires brand name licence US pregnancy AU pregnancy US D pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US legal status Rx dependency liability routes of administration Mouth Oral Identifiers CAS number ATC prefix C09 ATC suffix DA03 PubChem 9810581 KEGG Ref keggcite correct kegg KEGG D09197 Chemical data Valsartan hydrochlorothiazide International Nonproprietary Name INNs , trade name Diovan HCT is an antihypertensive pharmaceutical drug drug combination of an angiotensin II receptor antagonist with hydrochlorothiazide, ref Drugs.com http www.drugs.com mtm diovan hct.html Diovan HCT ref the most common diuretic to be combined with other blood pressure lowering substances. References reflist Agents acting on the renin angiotensin system Category Combination drugs Category Angiotensin II receptor antagonists cardiovascular drug stub zh ... more details
Arcanum duplicatum potassium sulfate , also known as panacea duplicata , in pre modern medicine , is a preparation of the caput mortuum , or the remaining residue from distillation or sublimation, of aqua fortis , by dissolving it in hot water, filtering, and evaporating it to a cuticle. It is then left to shoot. It was used as a diuretic and sudorific . The recipe was purchased for 500 dollars by the Karl Friedrich, Duke of Holstein Gottorp Duke of Holstein . Schroder, the prince s physician, wrote wonders of its great uses in hypochondriac al cases, continued and intermitting fever s, stone, scurvy , etc. References 1728 http digicoll.library.wisc.edu cgi bin HistSciTech HistSciTech idx?type turn&entity HistSciTech000900240170&isize L treatment stub Category Alchemical substances Category Traditional medicine ... more details
24 format work ref Pharmacology As a diuretic in particular a thiazide , trichlormethiazide encourages ... loop of Henle. This results in excretion of sodium, chloride and water, and thus acts as a diuretic ... hypotensive effects may not necessarily be due to its role as a diuretic. ref name drugbank Thiazides ... more details
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