Infobox Disease Name Endometrialhyperplasia Image Simple endometrialhyperplasia low mag.jpg Caption Micrograph showing simple endometrialhyperplasia, where the gland to stroma ratio is preserved but the glands have an irregular shape and or are dilated. Endometrial biopsy . H&E stain . DiseasesDB ... 3334 eMedicine mult MeshID D004714 Endometrialhyperplasia is a condition of excessive proliferation of the cells of the endometrium , or inner lining of the uterus . Most cases of endometrialhyperplasia ... estrogen replacement therapy . Endometrialhyperplasia is a significant risk factor for the development or even co existence of endometrial cancer , so careful monitoring and treatment of women with this disorder is essential. Classification Like other hyperplasia hyperplastic disorders, endometrialhyperplasia initially represents a physiology physiological response of endometrial tissue ... microscopic histopathology subtypes of endometrialhyperplasia are recognisable to the pathology ... doi ref Endometrialhyperplasia simple or complex Irregularity and cystic expansion of glands simple ... endometrial cancer. ref name Kurman cite journal author Kurman RJ, Kaminski PF, Norris HJ title The behavior of endometrialhyperplasia. A long term study of untreated hyperplasia in 170 patients ... 56 2 403 AID CNCR2820560233 3.0.CO 2 X ref Atypical endometrialhyperplasia simple or complex Simple ... atypical hyperplasia. references pending . Diagnosis Diagnosis of endometrialhyperplasia can be made ... EndometrialHyperplasia publisher UpToDate Online subscription required accessdate 2007 05 26 postscript None ref Treatment Treatment of endometrialhyperplasia is individualized, and may include hormonal ... of the pelvis and genitals DEFAULTSORT EndometrialHyperplasia Category Gynaecological cancer Category ... activity . These changes are similar to those seen in true cancer cells, but atypical hyperplasia does ... mentioned study found that 22 of patients with atypical hyperplasia eventually developed cancer ... more details
adrenal hyperplasiaEndometrialhyperplasia Hyperproliferation of the endometrium, usually ... administration of hormones. Atypical endometrialhyperplasia may represent an early neoplasia neoplastic process which can lead to endometrial cancer endometrial adenocarcinoma . Hemihyperplasia ... Name Hyperplasia Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D006965 Hyperplasia or hypergenesis means increase in number of cells cell proliferation ... is sometimes mixed with benign neoplasia benign tumor . Hyperplasia is a common preneoplastic ... Mosby Elsevier ref Hyperplasia is different from hypertrophy in that the Cellular adaptation adaptive cell change in hypertrophy is an increase in cell size cell size , whereas hyperplasia involves an increase in the number of cells. Image Hyperplasia vs Hypertrophy.svg thumb right 300px Simple illustration to show the difference between hyperplasia and hypertrophy . Difference from neoplasia Hyperplasia is considered to be a physiology physiological normal response to a specific stimulus ... in itself is abnormal. Causes Hyperplasia may be due to any number of causes, including ... dysfunction s, or Compensatory growth organ compensation for injury damage or disease elsewhere. Hyperplasia ... to pregnancy , thus preparing for future breast feeding . Hyperplasia may also be induced artificially ... and potent effect IGF has on the human body is its ability to cause hyperplasia, which is an actual ... of the cells. With IGF use, one is able to cause hyperplasia which actually increases the number of muscle ... can trigger hyperplasia, though this phenomenon has yet to be confirmed in humans. Hyperplasia ... Sci Sports Exerc. volume 26 issue 8 pages 973 977 year 1994 month Aug pmid 7968431 doi url ref Hyperplasia ... commonly known clinical forms of hyperplasia, or conditions leading to hyperplasia, are Benign prostatic hyperplasia , also known as prostate enlargement. Cushing s disease Physiopathology of hyperplasia ... more details
OPS301 OtherCodes Image Simple endometrialhyperplasia intermed mag.jpg thumb right Micrograph showing an endometrial biopsy with endometrialhyperplasia simple endometrialhyperplasia , where the gland ... of indication s for obtaining an endometrial biopsy in a non pregnant woman Women with chronic anovulation such as the polycystic ovary syndrome are at increased risk for endometrial problems and an endometrial biopsy may be useful to assess their lining specifically to rule out endometrialhyperplasia or endometrial cancer cancer . In women with abnormal vaginal bleeding the biopsy may indicate the presence of abnormal lining such as endometrialhyperplasia or endometrial cancer cancer . In patients ... . The endometrial biopsy is a medical office procedure that is used for sampling medicine sampling ... obtaining an endometrial biopsy as it may help in the gynecologic diagnosis, or even make the taking of a biospy superfluous if the lining is thin. If the endometrial lining is less than 5 mm thick on sonography, it is highly unusual to encounter endometrial cancer. ref name cfp The test ... test endometrial biopsy overview.html title Endometrial biopsy accessdate March 11, 2010 work The New ... 44 title Endometrial biopsy author Christiane Kuntz accessdate March 11, 2010 pmc 1952554 pmid 17872607 ... disease and coagulopathies. ref name cfp An endometrial biopsy usually cannot be done as an office ... and moved in and out to collect small pieces of endometrial tissue. Recently, the TruTest has been ... name nyt Endometrial Biopsy Pain Endometrial biopsy pain ref name org cite news url http www.endometrialbiopsy.net endometrial biopsy endometrial biopsy pain title Endometrial biopsy pain accessdate June 4, 2011 work Endometrial Biopsy ref is quite common. The reason that doctors spray the lidocain ... entain two or three instances of procuring a piece of the endometrium. Endometrial biopsy procedure Generally, an endometrial biopsy follows this process Image Gray1167.svg right thumb 1. The patient ... more details
, often develops in the setting of endometrialhyperplasia , and presents most often with vaginal bleeding . Endometrial carcinoma is the third most common cause of gynecologic cancer death behind ... menopausal women, often with a history of unopposed estrogen exposure and or endometrialhyperplasia ... high levels of estrogen endometrialhyperplasia hypertension polycystic ovary syndrome ref cite book ... of endometrialhyperplasia. Frank adenocarcinoma may be distinguished from atypical hyperplasia by the finding ...Cleanup date February 2010 Infobox disease Name Endometrial cancer Image Endometrioid endometrial adenocarcinoma low mag.jpg Caption Micrograph of endometrioid endometrial adenocarcinoma , the most common form of endometrial cancer . H&E stain . DiseasesDB 4252 ICD10 ICD10 C 54 1 c 51 ICD9 ICD9 182 ICDO ... 253 MeshID D016889 Endometrial cancer refers to several types of cancer malignancies that arise from the endometrium , or lining, of the uterus . Endometrial cancers are the most common gynecologic ... with bilateral salpingo oophorectomy is the most common therapeutic approach. Endometrial cancer ... endometrial cancers are carcinoma s usually adenocarcinoma s , meaning that they originate from the single layer of epithelium epithelial cells that line the endometrium and form the endometrial glands. There are many histopathology microscopic subtypes of endometrial carcinoma , including the common ... cell endometrial carcinomas. Some authorities have proposed that endometrial carcinomas be classified into two pathogenetic groups ref cite journal author Bokhman JV title Two pathogenetic types of endometrial ..., the uterine papillary serous carcinoma , the uterine clear cell carcinoma . FIGO grading of Endometrial ... to endometrial carcinomas , the uncommon endometrial stromal sarcomas are cancers that originate in the non ... 0 7216 7253 1 oclc doi ref gallery Image Endometrial stromal sarcoma gross.jpg Endometrial stromal sarcoma. Image Uterine carcinosarcoma.jpg Uterine carcinosarcoma. Image Endometrial adenocarcinoma ... more details
can be difficult, particularly when there is endometrialhyperplasia excessive thickening of the endometrium ...Infobox disease Name Endometrial polyp Image Polyp.Uterus.jpg Caption Endometrial polyp, viewed by sonography. DiseasesDB ICD10 ICD10 N 84 0 n 80 ICD9 ICD9 621 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID An endometrial polyp or uterine polyp is a tumor mass in the inner lining of the uterus. ref name PGU cite book author Jane A. Bates title Practical Gynaecological Ultrasound publisher Cambridge University Press location Cambridge, UK year 1997 pages isbn 1 900151 51 0 oclc doi accessdate ref They may have a large flat base Sessility medicine sessile or be attached to the uterus by an elongated pedicle pedunculated . ref name PGU ref name Mayo cite web title Uterine polyps publisher ... may be present, particularly in large polyps. ref name PGU Cause and symptoms No definitive cause of endometrial ... cite web title Endometrial Polyp publisher GPnotebook url http www.gpnotebook.co.uk simplepage.cfm ... red blood cells endometrial polyp low mag.jpg thumb right 200px Micrograph of an endometrial polyp. H&E stain . Endometrial polyps can be detected by vagina l Gynecologic ultrasonography ultrasound ... general anesthetic . ref name BBC Prognosis and complications Endometrial polyps are usually Benign tumor benign although some may be precancerous or cancerous . ref name Mayo About 0.5 of endometrial ... Although treatments such as hysteroscopy usually cure the polyp concerned, recurrence of endometrial ... last Kaunitz first Andrew M. title Asymptomatic Endometrial Polyps What Is the Likelihood of Cancer ... 440353 accessdate 2008 04 20 ref Risk factors and epidemiology Endometrial polyps usually occur ... doi 10.1111 j.1471 0528.2007.01545.x url ref Endometrial polyps occur in up to 10 of women. ref ... name Dew Structure Endometrial polyps can be solitary or occur with others. ref name DSTTS cite book ... with endometrial epithelium . ref name OGDT If they are pedunculated, they are attached by a thin ... more details
Orphan date September 2008 Unreferenced date November 2008 Endometrial arteries are those artery arteries that enter the intervillous space on the maternal side of the placenta within the uterus . They are also known as spiral arteries . They supply nutrition and oxygen to the fetus via the placenta. DEFAULTSORT Endometrial Arteries Category Arteries Category Female reproductive system biology stub ... more details
Interventions infobox Name PAGENAME Image Endometrial ablation 1.jpg Caption Hysteroscopic endometrial ablation ICD10 ICD9 ICD9proc 68.23 MeshID OPS301 OtherCodes HCPCSlevel2 Endometrial ablation is a medical procedure that is used to remove ablation ablate or destroy the endometrial lining of a uterus . This technique is most often employed for people who suffer from excessive or prolonged bleeding during their menstrual cycle but cannot or do not wish to undergo a hysterectomy . The procedure is most commonly done on an outpatient basis. Placenta accreta may occur if the patient becomes pregnant after endometrial ablation, so birth control is recommended. Procedure A number of competing procedures are available. ref name pmid19821278 cite journal author Lethaby A, Hickey M, Garry R, Penninx J title Endometrial resection ablation techniques for heavy menstrual bleeding journal Cochrane Database Syst Rev volume issue 4 pages CD001501 year 2009 pmid 19821278 doi 10.1002 14651858.CD001501.pub3 ref The HTA System ref Hydro ThermAblator System HTA . Instructions for use. 2005 Boston Scientific Corporation. ref uses a small telescope like device called a hysteroscope which is inserted into the uterus through the cervix, to help doctors safely confirm proper probe placement and to see the area they are treating. This device circulates heated saline which burns the lining of the uterus. This procedure will stop, or significantly decrease, menstrual bleeding. 94 of patients who have undergone this procedure reported a satisfactory decrease in menstrual flow. An alternative is the Thermachoice III balloon ref Gynecare Thermachoice III. Instructions for use. 2008 ETHICON, Inc. a Johnson ... Perforation of the uterus Burns to the uterus beyond the endometrial lining Pulmonary edema or embolism ... reflist Female genital procedures DEFAULTSORT Endometrial Ablation Category Gynecological surgery de Endometriumablation gl Ablaci n endometrial ... more details
Intimal hyperplasia is the thickening of the Tunica intima of a blood vessel as a complication of a reconstruction procedure or endarterectomy . Intimal hyperplasia is the universal response of a vessel to injury and is an important reason of late bypass graft failure, particularly in vein and synthetic vascular grafts. See also Hyperplasia Medical grafting External links http dissertations.ub.rug.nl faculties medicine 2002 g.j.toes Intimal hyperplasia, the obstacle in bypass grafts disease stub Category Diseases of arteries, arterioles and capillaries ... more details
Orphan date February 2009 Lymphoid hyperplasia or Lymphoid hypertrophy is the rapid growth cell growth proliferation of normal cells that resemble lymph tissue. ref http www.nlm.nih.gov medlineplus ency article 001320.htm MedlinePlus Medical Encyclopedia Lymphoid hyperplasia Bot generated title ref Lymph Node Anatomy The lymph node is a round or reniform organ that is usually no larger than 1cm in diameter. It is composed of a cortex, paracortex, and medulla with sinuses distributed throughout. The paracortex is known as the T cell zone due to the presence of T cells, and the cortex is composed of follicles of B cells and is known as the B cell zone. Each of these locations can undergo hyperplasia. Follicular Hyperplasia Follicular hyperplasia is a stimulation of the B cell compartment. It is caused by an abnormal proliferation of secondary follicles and occurs principally in the cortex without broaching the lymph node capsule. The follicles are cytologically polymorphous, are often polarized, and vary in size and shape. Follicular hyperplasia must be distinguished from follicular lymphoma bcl 2 protein is expressed in neoplastic follicles, but not reactive follicles . Paracortical Hyperplasia Paracortical hyperplasia in the preferential stimulation of the T cell compartment. It is caused by an abnormal expansion of the interfollicular zones but is confined within the lymph node capsule. The population of the compartment is cytologically polymorphous. Paracortical hyperplasia may be accompanied by vascular proliferation. Must be distinguished from monomorphous T cell lymphoma. Sinus Hyperplasia Sinus hyperplasia is the preferential stimulation of the histiocytic tissues macrophage compartment. Histological features include distention or engorgement of both subscapular and inatraparenchymal sinuses by benign histiocytes which may be hemophagocytic. Sinus hyperplasia may be associated with non hematolymphoid malignancy. Complications It is one common source of appendicitis ... more details
Atypical hyperplasia is a benign noncancerous condition in which cells look abnormal under a microscope and are increased in number. External links http www.cancer.gov Templates db alpha.aspx?CdrID 46522 Atypical hyperplasia entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict oncology stub Category Benign neoplasms ar ... more details
Refimprove date December 2009 Orphan date February 2009 Neuroendocrine hyperplasia is a wikt progressive progressive hyperplasia hyperplastic process that ultimately results in wikt obliterate obliterative fibrosis of predominantly the lung pulmonary tree the lungs . It is characterized by tachypnea , Hypoxia medical hypoxia , and retractions . ref name Springerlink cite web url http www.springerlink.com content pw8x713728772g13 title Neuroendocrine cell hyperplasia of infancy NCHI publisher University of Cincinnati College of Medicine year 2006 ref There is no currently recognized treatment for the relentless progression of this disorder. References Reflist 3 DEFAULTSORT Neuroendocrine Hyperplasia Category Diseases and disorders Category Disease stubs Disease stub ... more details
Infobox disease Name Thymus hyperplasia Image Caption DiseasesDB ICD10 ICD10 E 32 0 e 20 ICD9 ICD9 254.0 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D013952 Thymus hyperplasia or thymic hyperplasia refers to an enlargent hyperplasia of the thymus . ref name urleMedicine Surgery of the Thymus Gland Article by Said Fadi Yassin Cite web url http www.emedicine.com med TOPIC3195.HTM section ThymicHyperplasia title eMedicine Surgery of the Thymus Gland Article by Said Fadi Yassin format work accessdate ref It is not always a disease state. The size of the thymus usually peaks during adolescence, and atrophies in the following decades. Before the immune function of the thymus was well understood, the enlargement was sometimes seen as a cause for alarm, and justification for surgical reduction. This approach is much less common today. It can be associated with myasthenia gravis . ref Medcyclopaedia vii t thymus hyperplasia ref ref name pmid8941638 Cite journal author Murakami M, Hosoi Y, Negishi T, et al. title Thymic hyperplasia in patients with Graves disease. Identification of thyrotropin receptors in human thymus journal J. Clin. Invest. volume 98 issue 10 pages 2228 34 year 1996 month November pmid 8941638 pmc 507671 doi 10.1172 JCI119032 ref MRI can be used to distinguish it from thymoma . ref name pmid17463136 Cite journal author Inaoka T, Takahashi K, Mineta M, et al. title Thymic hyperplasia and thymus gland tumors differentiation with chemical shift MR imaging journal Radiology volume 243 issue 3 pages 869 76 year 2007 month June pmid 17463136 doi 10.1148 radiol.2433060797 url http radiology.rsnajnls.org cgi pmidlookup?view long&pmid 17463136 ref References Reflist Thymus disorders Medicine stub Category Immune system disorders ... more details
Refimprove date June 2009 Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICD9 706.9 ICDO OMIM MedlinePlus eMedicineSubj article eMedicineTopic 1059368 MeshID Sebaceous hyperplasia is a disorder of the sebaceous gland s in which they become enlarged. ref name Andrews cite book author James, William D. Berger, Timothy G. et al. title Andrews Diseases of the Skin clinical Dermatology publisher Saunders Elsevier location year 2006 pages isbn 0 7216 2921 0 oclc doi accessdate ref Rp 662 date June 2009 producing yellow, shiny bumps on the face. These bumps are a natural response to the maternal hormones of pregnancy and usually resolve on their own within a few weeks after delivery. Sebaceous gland s are glands located within the skin and are responsible for secreting an oily substance named sebum . They are commonly associated with hair follicle s but they can be found in hairless regions of the skin as well. Their secretion lubricates the skin, protecting it from drying out or becoming irritated. Fact date June 2009 Sebaceous hyperplasia generally affects newborns as well as middle aged to elderly adults. The symptoms of this condition are 1 5 mm papule s on the skin, mainly on the forehead, nose and cheeks, and seborrheic facial skin. The papules may be cauliflower shaped. Acne vulgaris Acne is also a symptom of this glandular disorder. It differs from the type of acne that affects adolescents and young adults in that it is of a more abnormally discolored composition. Fact date June 2009 See also Sebaceous carcinoma Sebaceous adenoma Skin lesion References reflist Category Epidermal nevi, neoplasms, cysts Epidermal growth stub Disorders of skin appendages ... more details
of a larger mixed group of lesions previously called endometrialhyperplasia ref name A cite book author Mutter GL, Duska L, Crum CP chapter Endometrial Intraepithelial Neoplasia editor Crum ... year 2003 pages 221 232 ref The EIN diagnostic schema is intended to replace the previous endometrialhyperplasia classification as defined by the World Health Organization in 1994, which have been separated into benign benign endometrialhyperplasia and premalignant EIN classes in accordance with their behavior ... ras protooncogene in human endometrialhyperplasia and carcinoma journal Cancer Res. volume ... conditions such as benign endometrialhyperplasia a field effect in endometrial tissue caused by excessive ... from EIN Table II includes benign endometrialhyperplasia and carcinoma ref name B Table ... br Class Endometrial br Topography Functional br Category Treatment Benign br endometrial br hyperplasia ...Endometrial Intraepithelial Neoplasia, EIN is a premalignant lesion of the uterine lining that predisposes to endometrioid endometrial adenocarcinoma. It is composed of a collection of abnormal endometrial ... to the most common form of uterine cancer endometrial adenocarcinoma , endometrioid type. History ... of endometrial carcinoma include exposure to estrogens without opposing progestins, obesity, diabetes ... A, Faquin WC title Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized ... author Jovanovic AS, Boynton KA, Mutter GL title Uteri of women with endometrial carcinoma contain a histopathological ... inactivation identifies monoclonal endometrial cancers and precancers journal Am. J. Pathol. volume ... and genetic alterations in endometrial pipelle biopsy and its surgical specimen counterpart journal ... hypermethylation is an early event in human endometrial tumorigenesis journal Am. J. Pathol. volume ... appear in the premalignant phase of both microsatellite stable and unstable endometrial carcinogenesis ... suppressor gene in endometrial hyperplasias journal Cancer Res. volume 58 issue 12 pages 2500 3 ... more details
uterine sarcoma Image EndometrialStromalSarcoma.JPG thumbnail right Endometrial Stromal Sarcoma, High Grade Undifferentiated uterine sarcoma, or undifferentiated high grade endometrial stromal sarcoma, does not resemble normal endometrial stroma and behaves much more aggressively, frequently ... , t 7 17 p15 q21 , occurs in endometrial stromal sarcoma. This translocation leads to the fusion ... transcript with anti apoptotic properties. Interestingly, even normal endometrial stroma cells express ... more details
Refimprove date January 2008 Autologous Endometrial Coculture is a technique of assisted reproductive technology . It involves placing a patient s fertilized eggs on top of a layer of cells from her own uterine lining, creating a more natural environment for embryo development and maximizing the chance for an in vitro fertilization IVF pregnancy. How Coculture is performed A typical Coculture cycle consists of the following steps br 1. Once a patient has been deemed an appropriate candidate for the procedure, she undergoes an endometrial biopsy during which a small piece of her uterine lining is removed. br 2. The uterine lining sample is sent to a research lab, where it is treated, purified and frozen. br 3. The patient then undergoes a typical IVF cycle and is given medication to stimulate egg growth in her ovaries . br 4. The patient s eggs are retrieved and mixed with the spermatozoon sperm . At this time, the lab begins thawing and growing her endometrial cells. br 5. Once fertilization is confirmed, the patient s embryo s are placed on top of her own and now thawed endometrial cells. br 6. Over the next two days, the embryos are closely monitored for growth and development. br 7. The patient s embryos are transferred into her uterus for implantation and pregnancy . The potential candidate Coculture can be an effective treatment for patients who have failed previous IVF cycles or who have poor embryo quality. Advantages A study of 12,377 embryo cultures showed that endometrial coculture is Statistical significance significantly better than sequential culture media the rates fraction reaching blastocyst stage were 56 versus 46 in the coculture versus the sequential system, respectively, with own oocytes. With eggs from Egg donation ovum donations , the rates were 71 versus 56 , respectively. Pregnancy rate s were 39 vs. 28 and implantation rate s were 33 vs. 21 . ref ... outcome and secretome profile of implanted blastocysts obtained after coculture in human endometrial ... more details
Inflammatory papillary hyperplasia is an oral pathology oral pathologic condition that appears in the mouth as an hyperplasia overgrowth of tissue usually beneath a denture. It is associated with poor denture hygiene, denture overuse, and ill fitting dentures. The exact cause of inflammatory papillary hyperplasia is unknown. In people who wear dentures 24 hours a day, its incidence is around 20 . It appears as an asymptomatic erythematous area, usually the hard palate, with a pebbly surface. Nonetheless, it may also occur on the hard palates of patients who are chronic mouth breathers. Sometimes, this disease can found in conjunction with another denture related disease, an epulis fissuratum . The appearance of an epulis fissuratum microscope microscopically is an overgrowth of stratified squamous epithelium cell biology cells . Depending on the how advanced the condition is, pseudoepitheliomatous hyperplasia may be present. In mild cases, treatment consists of removal of the denture with spontaneous regression of the disease. In advanced cases of inflammatory papillary hyperplasia, surgery may be needed, along with behavioral modification toward proper denture use. References Kahn, Michael A. Basic Oral and Maxillofacial Pathology. Volume 1. 2001. disease stub dentistry stub Category Oral pathology ... more details
Infobox Disease Name Intravascular papillary endothelial hyperplasia Image Caption DiseasesDB ICD10 D21 ILDS D21.M20 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Intravascular papillary endothelial hyperplasia also known as Masson s hemangio endotheliome vegetant intravasculaire, ref name Bolognia Masson s lesion, ref name Bolognia Masson s pseudoangiosarcoma, ref name Bolognia Masson s tumor, ref name Bolognia and Papillary endothelial hyperplasia ref name Bolognia cite book author Rapini, Ronald P. Bolognia, Jean L. Jorizzo, Joseph L. title Dermatology 2 Volume Set publisher Mosby location St. Louis year 2007 pages isbn 1 4160 2999 0 oclc doi accessdate ref may mimic angiosarcoma, with lesions that are red or purplish 5 mm to 5 cm papules and deep nodules on the head, neck, or upper extremities. ref name Bolognia ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 592 See also List of cutaneous conditions References Reflist Soft tissue tumors and sarcomas DEFAULTSORT Intravascular Papillary Endothelial Hyperplasia Category Dermal and subcutaneous growths Dermal growth stub ... more details
Infobox Disease Name PAGENAME Image Focal nodular hyperplasia intermed mag.jpg Caption Micrograph of focal nodular hyperplasia. H&E stain . DiseasesDB 33467 ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj radio eMedicineTopic 286 MeshID D020518 Focal nodular hyperplasia FNH is a benign tumour of the liver hepatic tumour , which is the second most prevalent tumour of the liver the first is hepatic hemangioma . It is usually asymptomatic, rarely grows or bleeds, and has no malignant potential. This tumour is often resected because it is difficult to distinguish from adenoma Liver hepatic adenoma . Presentation Focal nodular hyperplasia s most recognizable gross feature is a central stellate scar seen in 60 70 of cases. Microscopically, a lobular proliferation of bland appearing hepatocytes with a bile ductular proliferation and malformed vessels within the fibrous scar is the most common pattern. Other patterns include telangiectatic, hyperplastic adenomatous, and lesions with focal large cell dysplasia. ref name Nguyen cite journal author Nguyen BN, Fl jou JF, Terris B, Belghiti J, Degott C title Focal nodular hyperplasia of the liver a comprehensive pathologic study of 305 lesions and recognition of new histologic forms journal Am. J. Surg. Pathol. volume 23 issue 12 pages 1441 54 year 1999 month December pmid 10584697 doi url http meta.wkhealth.com pt pt core template journal lwwgateway media landingpage.htm?issn 0147 5185&volume 23&issue 12&spage 1441 ref Rarely, these lesions may be multiple or can occur as part of a syndrome with hemangiomas, epithelioid hemangioendothelioma, hepatic adenomas, fibrolamellar hepatocellular carcinoma, vascular malformations of the brain, meningiomas, and or astrocytomas. ref name Nguyen Notes Reflist References refbegin cite journal author Hsee LC, McCall JL, Koea JB title Focal nodular hyperplasia what are the indications for resection ... hyperplasia ... more details
Infobox disease Name PAGENAME Image Pseudoangiomatous stromal hyperplasia high mag.jpg Caption High magnification micrograph of pseudoangiomatous stromal hyperplasia showing the characteristic small, anastomosing blood vessel like channels. H&E stain . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID In breast pathology , pseudoangiomatous stromal hyperplasia , commonly abbreviated PASH , is an overgrowth of myofibroblasts myofibroblastic cell biology cell s and has an appearance similar to fibroadenoma fibroadenomatoid changes . ref name powell cite journal author Powell CM, Cranor ML, Rosen PP title Pseudoangiomatous stromal hyperplasia PASH . A mammary stromal tumor with myofibroblastic differentiation journal Am. J. Surg. Pathol. volume 19 issue 3 pages 270 7 year 1995 month March pmid 7872425 doi 10.1097 00000478 199503000 00004 url ref The diagnostic significance is currently uncertain, but it appears to be benign . Diagnosis Image Pseudoangiomatous stromal hyperplasia a intermed mag.jpg thumb right Intermediate magnification micrograph showing the relative abundance of stroma in a case of PASH. H&E stain . The diagnosis of PASH is by biopsy . The important differential diagnosis is angiosarcoma , from which it was first differentiated in 1986. ref cite journal author Vuitch MF, Rosen PP, Erlandson RA title Pseudoangiomatous hyperplasia of mammary stroma journal Hum. Pathol. volume 17 issue 2 pages 185 91 year 1986 month February pmid 3949338 doi 10.1016 S0046 8177 86 80292 1 url ref Differential diagnosis Fibroadenoma Angiosarcoma ref cite journal author de Saint Aubain Somerhausen N, Larsimont D, Cluydts N, Heymans O, Verhest A title Pseudoangiomatous hyperplasia of mammary stroma in an HIV patient journal Gen Diagn Pathol volume 143 issue 4 pages 251 4 year 1997 month December pmid 9489960 doi url ref Treatment The management of PASH is surgery surgical excision . ref name powell References reflist 2 External links http www.thedoctorsdoctor.com ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 L98.8 ILDS L98.812 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D019310 Cutaneous lymphoid hyperplasia also known as borrelial lymphocytoma, ref name Bolognia cite book author Rapini, Ronald P. Bolognia, Jean L. Jorizzo, Joseph L. title Dermatology 2 Volume Set publisher Mosby location St. Louis year 2007 pages isbn 1 4160 2999 0 oclc doi accessdate ref Lymphadenosis benigna cutis, Lymphocytoma cutis, Pseudolymphoma, Pseudolymphoma of Spiegler and Fendt, ref name Bolognia Sarcoidosis of Spiegler and Fendt, ref name Bolognia Spiegler Fendt lymphoid hyperplasia, ref name Bolognia and Spiegler Fendt sarcoid refers to a groups of benign cutaneous disorders characterized by collections of lymphocyte s, macrophage s, and dendritic cell s in the skin. Image Borrelial lymphocytoma.jpg thumb borrelial lymphocytoma on the cheek ref name Andrews cite book author James, William D. Berger, Timothy G. et al. title Andrews Diseases of the Skin clinical Dermatology publisher Saunders Elsevier location year 2006 pages isbn 0 7216 2921 0 oclc doi accessdate ref rp 725 Conditions included in this groups are ref name Andrews rp 725 Cutaneous lymphoid hyperplasia with nodular pattern Cutaneous lymphoid hyperplasia with bandlike and perivascular patterns Jessner lymphocytic infiltrate of the skin See also Skin lesion List of cutaneous conditions References reflist Cutaneous condition stub Lymphoid malignancy Category Lymphoid related cutaneous conditions ... more details
Drug related gingival hyperplasia is a cutaneous condition characterized by enlargement of the gums noted during the first year of drug treatment. ref name Bolognia cite book author Rapini, Ronald P. Bolognia, Jean L. Jorizzo, Joseph L. title Dermatology 2 Volume Set publisher Mosby location St. Louis year 2007 pages isbn 1 4160 2999 0 oclc doi accessdate ref See also Desquamative gingivitis List of cutaneous conditions References reflist Dermatology stub Category Drug eruptions ... more details
Walleye Epidermal Hyperplasia Virus Type 1 and Type 2 Deleted image removed File Walleye Lesion.jpg thumb alt text Arrows indicate thickened patches of infected skin on a walleye caused by epidermal hyperplasia virus. Walleye Epidermal Hyperplasia Virus is a retrovirus classified under, Epsilonretrovirus es http viralzone.expasy.org all by species 92.html , a recent genus addition to the family of Retroviridae http viralzone.expasy.org all by protein 71.html . There are three genome sequenced and identified exogenous retroviruses of this genus which include two known types WEHV 1 and WEHV 2 associated with walleye epidermal hyperplasia disease. Both viral types are confirmed to be the causative agents of the neoplastic condition in the freshwater fish species, the North American Walleye Stizostedion vitreum . The specific association of retroviral infection with proliferative lesions in fish is based on the presence of retrovirus like particles observed via electron microscopy and reverse transcriptase activity using reverse transcriptase polymerase chain reaction techniques from neoplastic tissue. Although both virus types have been observed in lesions of diseased fish, each cell of the infected tissue is host to a specific virus. Transmission studies have also shown that WEHV 2 has been the more proliferative agent of the condition as compared to WEHV 1. ref name WDSV Cite journal author Rovnack, J., Quakenbush, SL. title Walleye Dermal Sarcoma Virus Molecular Biology and Oncogenesis. journal Viruses volume 2 pages 1984 1999 year 2010 month September doi 10.3390 v2091984 url http www.mdpi.com 1999 4915 2 9 1984 ref ref name pmid10516048 Cite journal author LaPierre LA, Holzschu ... walleye epidermal hyperplasia virus types 1 and 2 evidence for a gene duplication. journal J.Virol. ... Retroviruses Are Associated with Walleye Discrete Epidermal Hyperplasia journal J.Virol volume ... ref http jvi.asm.org content 72 4 3484 F2.large.jpg Condition Walleye epidermal hyperplasia lesions ... more details
Infobox disease Name PAGENAME Image Atypical ductal hyperplasia very low mag.jpg Width 250 Caption Very low magnification micrograph of atypical ductal hyperplasia ADH . The piece with ADH was circled by the pathologist with a marker, as it is so small, and sent for an additional opinion. H&E stain . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Atypical ductal hyperplasia , abbreviated ADH , is the term used for a benign lesion of the breast that indicates an increased risk of breast cancer . ref name urlUnderstanding Breast Changes National Cancer Institute cite web url http www.cancer.gov cancertopics understanding breast changes page6 F8 title Understanding Breast Changes National Cancer Institute format work accessdate ref The name of the entity is descriptive of the lesion ADH is characterized by cellular proliferation hyperplasia within one or two breast ducts and histomorphology histomorphologic architectural abnormalities, i.e. the cells are arranged in an abnormal or atypical way. In the context of a core biopsy core needle biopsy , ADH is considered an indication for a breast lumpectomy, also known as a surgical excisional biopsy, to exclude the presence of breast cancer . ref name pmid7717215 cite journal author Liberman L, Cohen MA, Dershaw DD, Abramson AF, Hann LE, Rosen PP title Atypical ductal hyperplasia diagnosed at stereotaxic core biopsy of breast lesions an indication for surgical biopsy journal AJR Am J Roentgenol volume ... rates of atypical ductal hyperplasia diagnosed at stereotactic vacuum assisted breast biopsy 9 versus ... at surgery of atypical ductal hyperplasia diagnosed on core biopsy. journal Breast volume ... Additional images gallery Image Atypical ductal hyperplasia low mag.jpg Low mag. Image Atypical ductal hyperplasia high mag.jpg High mag. gallery References reflist 2 External links http www.hopkinsmedicine.org ... What is atypical ductal hyperplasia? hopkinsmedicine.org Breast neoplasia Category Benign neoplasms ... more details
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