Image Epipen.jpg thumb 300px An old version of a 0.3 mg EpiPen auto injector An epinephrine autoinjector is a medical device used to deliver a measured dose or doses of epinephrine also known as adrenaline using autoinjector technology, most frequently for the treatment of acute allergic reaction s to avoid or treat the onset of anaphylactic shock . Trade names for this device include EpiPen , Twinject , Adrenaclick , Anapen , and Jext . The EpiPen was originally derived from the Mark I NAAK ComboPen , a product developed for the military for treating exposure to nerve agents. ref cite web url http www.tampabay.com news humaninterest epipen inventor helped millions and died in obscurity 1038756 title EpiPen inventor helped millions and died in obscurity publisher St. Petersburg Times date accessdate 2010 07 07 ref Design The devices contain a spring loaded needle that exits the tip of the device in some cases through a sterile membrane and into the recipient s body to deliver the medication. Epinephrine autoinjectors contain a pre determined dose of epinephrine, usually between 300 g ref name epipen ref cite web publisher Lincoln Medical Ltd url http www.anapen.co.uk downloads ... ref and 500 g ref name epipen ref cite web publisher Lincoln Medical Ltd url http www.anapen.co.uk ... made Pediatrics pediatric dosed versions available at 150 g of active ingredient, ref name epipen cite web url http www.epipen.com epipen dosing.aspx title Epipen and Epipen Jr Dosing & 124 Epinephrine Dose & 124 Anaphylaxis publisher EpiPen date accessdate 2010 07 07 ref ref cite web publisher ..., Canada, Turkey, Australia, Greece and South Africa . Epipen 0.3 mg and Epipen Jr. 0.15 ... 19, 2007. refend External links http www.epipen.com US EpiPen information http www.twinject.com ... Training video for EpiPen and Anapen from the Anaphylaxis Campaign UK http www.twinject.com injector ... ja nn EpiPen es Autoinyector de epinefrina ... more details
wiktionary pen A pen is a writing instrument which applies ink to a surface, usually paper. Pen may also refer to Pen enclosure , an enclosure for domestic animals Pigpen , an enclosure for pigs Sea pen , an animal Sea pen aquaculture , another name for a sea cage , used in fish farming The Pen , an episode of the TV series Seinfeld Pen, an abbreviation of prison penitentiary Pen can be slang for penitentiary Pen, an adult female swan Pen, Maharashtra , a town in India, in the Raigad district near Mumbai Pen, the much reduced and entirely internal shell of some cephalopod mollusc s, especially squid Pens Game , a card game Pens , a shortened nickname of the Pittsburgh Penguins of the NHL Pen play , a play by David Marshall Grant Olympus Pen , a family of half frame film cameras manufactured by Olympus Yehuda Pen , a Jewish Belarusian artist Gladius cephalopod , a hard internal bodypart found in certain cephalopods An insulin pen or other autoinjector such as an EpiPen See also PEN disambiguation disambig el nl Pen doorverwijspagina ja ... more details
chembox ImageFile D DOPA.png ImageSize IUPACName R 2 Amino 3 3,4 dihydroxyphenyl propanoic acid OtherNames Section1 Chembox Identifiers ChemSpiderID 83260 InChI 1 C9H11NO4 c10 6 9 13 14 3 5 1 2 7 11 8 12 4 5 h1 2,4,6,11 12H,3,10H2, H,13,14 t6 m1 s1 InChIKey WTDRDQBEARUVNC ZCFIWIBFBC CASNo 5796 17 8 PubChem 92222 SMILES O C O C H N Cc1cc O c O cc1 Section2 Chembox Properties Formula C 9 H 11 N 1 O 4 MolarMass 197.19 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition small D small DOPA small D small 3,4 d ihydr o xy p henyl a lanine Dextrodopa is similar to L DOPA small L small DOPA Levodopa , but with opposite chirality chemistry chirality . levorotation Levo and dextrorotation dextro rotation reference a molecule s ability to rotate planes of polarized light in either direction. Whereas small L small DOPA is moderately effective in the therapy treatment of Parkinson s disease PD , small D small DOPA is biologically activity chemistry inactive . See also L DOPA small L small DOPA Levodopa Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc. L DOPS small L small DOPS Droxidopa Methyldopa Aldomet, Apo Methyldopa, Dopamet, Novomedopa, etc. Dopamine Intropan, Inovan, Revivan, Rivimine, Dopastat, Dynatra, etc. Norepinephrine Noradrenaline Levophed, etc. Epinephrine Adrenaline Adrenalin, EpiPen, Twinject, etc. References reflist Category Aromatic amino acids Category Catecholamines pharm stub et 3,4 dih droks fen lalaniin fa ... more details
Infobox Disease Name Seafood allergy Image Caption DiseasesDB ICD10 ICD9 ICD9 V15.04 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Seafood allergy is a type of food allergy . It is a hypersensitivity to diet nutrition dietary substances from shellfish , scaly fish or crustaceans , causing an overreaction of the immune system, which may lead to severe physical symptoms for millions of people. ref National Institutes of Health, NIAID Allergy Statistics 2005 http www.niaid.nih.gov factsheets allergystat.htm ref The Asthma and Allergy Foundation of America estimates that the majority of pediatric and adult food allergy patients have a seafood allergy. ref Allergy Facts and Figures, Asthma and Allergy Foundation of America http www.aafa.org display.cfm?id 9&sub 20&cont 518 ref It occurs mainly but not exclusively in adults. Allergic reactions may result when the susceptible person is not consuming the allergenic substance, by exposure to vapours resulting from cooking of seafood or even preparation or handling. ref cite web title Seafood Fish, Crustaceans and Shellfish One of the nine most common food allergens url http www.inspection.gc.ca english fssa labeti allerg fispoie.shtml publisher Canadian Food Inspection Agency date 2009 06 12 accessdate 2009 06 21 ref Treatment Seafood allergies are usually treated with an exclusion diet and vigilant avoidance of foods that may be contaminated with shellfish or fish ingredients and or oils. The most severe seafood allergy reaction is called anaphylaxis , ref National Report of the Expert Panel on Food Allergy Research, NIH NIAID 2003 http www3.niaid.nih.gov about organization dait PDF june30 2003.pdf ref which is an emergency, requiring immediate attention. It is treated with Epinephrine , which can be administered with an EpiPen . See also List of allergies References For more information reflist External links http www.aafa.org Asthma and Allergy Foundation of America http www.nih.gov The National Institutes of ... more details
Infobox Book See Wikipedia WikiProject Novels or Wikipedia WikiProject Books name Cloud Busting image File Cloud Busting cover.jpg 200px image caption author Malorie Blackman illustrator cover artist country United Kingdom language English language English series genre Children s literature Children s publisher Doubleday publisher Doubleday pub date September 2, 2004 pages 146 pp isbn 978 0385607964 congress PZ7.B532337 Clo 2004 oclc 56642254 preceded by followed by Cloud Busting is a children s novel by Malorie Blackman , published in 2004. It is written in verse, with each chapter using a different type of poetry. The novel won the Nestl Smarties Book Prize Nestl Children s Book Prize Silver Award and was longlisted for the Carnegie Medal . ref http www.booktrusted.co.uk nestle Nestl Children s Book Prize ref ref http www.carnegiegreenaway.org.uk The CILIP Carnegie Medal & Kate Greenaway Children s Book Awards ref Plot The story begins when Mr Mackie, the teacher, assigns the homework to the class to write a poem. Sam wants to write his poem about Davey. Alex, his ex best friend mocks him for doing so. Sam quotes I want to write my poem about Davey Because now he s gone And I can t get him out of my head. Davey, or Fizzy Feet is a new boy. Everyone except Alicia hates him. He has holes in his jumper, and strange ideas fill his mind. Sam, the school bully, makes fun of him. He dislikes Davey as much, if not more, than everyone else. That is, until Davey saves his life, pulling him from in front of a speeding vehicle. The two soon become friends. Davey s way of looking at life begins to seem fun. Sam learns that Davey has an allergy to peanuts, and Davey tells him to keep it a secret as he didn t want a fuss. But, in front of his ex best friend, the bully, Alex, he accidentally lets it slip big mistake. Alex, as a joke, offers Davey a part of his sandwich, with a peanut slipped inside. Davey immediately has an allergic reaction, and Mr Mackie is forced to use the ... more details
Multiple issues BLP sources May 2011 orphan January 2011 notability December 2009 Aubert Vanderlinden is a ballet dancer ref cite news url http articles.sfgate.com 2009 03 01 living 17212960 1 allergic reactions epipen severely allergic children title Lifesaving lesson highlights birthday bash last Zinko first Carolyne work San Francisco Chronicle publisher March 1, 2009 accessdate 14 May 2011 ref and choreographer, he was born in 1985 , in Uccle , Belgium . After starting ballet with Piotr Nardelli in Brussels , Aubert Vanderlinden continued his classes at the Paris Opera Ballet school and later on, joined the prestigious ballet company in 2003. During the season 2004 2005, we could particularly appreciate his talent in the creation of Suzanne Linke ich bin... , he did as well the same year his debut as a choreographer at the Bastille Opera with a piece entitled In memoriam . With the Paris Opera Ballet , he performed ballets by George Balanchine , Jerome Robbins , William Forsythe dancer William Forsythe , Patrice Bart and so on. In 2006, Aubert makes his debut as a choreographer at the Bastille opera with a piece entitled In Memoriam . ref cite news url http www.altamusica.com danse document.php?action MoreDocument&DocRef 3057&DossierRef 2724 title Review Alta Musica ref In 2006, Aubert Vanderlinden won the Bronze medal in the senior category of the 22nd Varna International Ballet Competition international ballet competition of Varna , in Bulgaria . ref cite news url http www.varna ibc.org laureates.html title Varna IBC official website ref In 2007, Aubert Vanderlinden joined the San Francisco Ballet where he danced a principal role in the creation the ruins proclaim the building was beautiful.. choreographed by James Kudelka at the occasion of the new works festival 2008 organized for the 75th anniversary of the San Francisco Ballet , he also danced Ibsen s House of Val Caniparoli created for the same occasion. In San Francisco , Aubert Vanderlinden performed ba ... more details
refimprove date February 2007 Image AutoinjectorMarkI.jpg right thumb 250px A variety of autoinjectors in use with the Military of the United States US Armed Forces An autoinjector or auto injector is a medical device designed to deliver a single Dose biochemistry dose of a particular typically life saving medication drug . Most autoinjectors are spring loaded syringe s. By design, autoinjectors are easy to use and are intended for self administration by patients, or administration by untrained personnel. The site of injection depends on the drug loaded, but it typically is administered into the thigh or the buttocks . The injectors were initially designed to overcome the hesitation associated with self administration of the needle based drug delivery device . Design The autoinjector keeps the needle tip shielded prior to injection and also has a passive safety mechanism to prevent accidental firing injection . Injection depth can be adjustable or fixed and a function for needle shield removal may be incorporated. Just by pressing a button, the syringe hypodermic needle needle is automatically inserted and the drug is delivered. Once the injection is completed some auto injectors have visual indication to confirm that the full dose has been delivered. Autoinjectors contain glass syringes, this can make them fragile and contamination can occur. More recently, companies http www.ovalmedical.com have been looking into making autoinjectors syringes out of plastic to prevent this issue. Examples Anapen, EpiPen s, or the recently introduced Twinject , which is often prescribed to people who are at risk for anaphylaxis . Rebiject and Rebiject II autoinjectors for Rebif , the drug for interferon beta 1a used to treat Multiple Sclerosis . SureClick autoinjector is a combination product for drugs Enbrel or Aranesp to treat arthritis or anemia , respectively. Military use Autoinjectors are often used in the military to protect personnel from chemical warfare agents. In the Uni ... more details
Cleanup date March 2010 Soy allergy is a type of food allergy . It is a hypersensitivity to diet nutrition diet ary substances from soy causing an overreaction of the immune system which may lead to severe physical symptoms for millions of people. ref National Institutes of Health, NIAID Allergy Statistics 2005 http www.niaid.nih.gov factsheets allergystat.htm ref The Asthma and Allergy Foundation of America estimates soy is among the nine most common food allergens for pediatric and adult food allergy patients. ref Allergy Facts and Figures, Asthma and Allergy Foundation of America http www.aafa.org display.cfm?id 9&sub 20&cont 518 ref It is usually treated with an exclusion Dieting diet and vigilant avoidance of foods that may be contaminated with soy ingredients. The most severe food allergy reaction is called anaphylaxis ref National Report of the Expert Panel on Food Allergy Research, NIH NIAID 2003 http www3.niaid.nih.gov about organization dait PDF june30 2003.pdf ref and is a medical emergency requiring immediate attention and treatment with Epinephrine . Reactions and treatment Some people who are allergic to soy protein may have an extreme allergic reaction and go into anaphylactic shock anaphylaxis . In cases of anaphylaxis, emergency medical personnel typically administer epinephrine available as an autoinjector , such as EpiPen and an antihistamine such as Benadryl diphenhydramine . In event of an allergic reaction , the victim should see a physician or immediately go to the emergency room, as anaphylaxis can be fatal if not treated immediately. Food sources of soy protein Many fast food restaurant s commonly use soy protein in hamburger buns soy flour hamburger meat soy protein and hydrolyzed vegetable protein HVP in sauces. On their respective websites, McDonald s and Burger King list soy flour as an ingredient in their hamburger buns. ref http www.mcdonalds.com app controller.nutrition.categories.ingredients.index.html McDonald s Nutrition Informatio ... more details
DISPLAYTITLE Safe House notability Episode date March 2011 unreferenced date March 2011 All plot date March 2011 Infobox television episode Title Safe Series House TV series House Image Deleted image removed File 2Safe.jpg 250px Caption Season 2 Episode 16 Director F lix Enr quez Alcal Felix Alcala Writer Peter Blake writer Peter Blake Teleplay Story Producer Music Photographer Editor Production Airdate Start date 2006 4 4 Length Guests Michelle Trachtenberg as Melinda Bardach Jake McDorman as Dan Mel Harris as Barbara Bardach Lance Guest as Lewis Bardach Season list Infobox House TV series season 2 episode list Prev Next Episode list List of House episodes List of House episodes Safe is the sixteenth episode of the second season of House TV series House , which premiered on the Fox Broadcasting Company Fox network on April 4, 2006. Plot The episode starts out with teenager Melinda s boyfriend, Dan, visiting her at her house. Her mother, Mrs. Bardach, makes Dan wash his hands up to the elbows and when he sneezes, she questions him closely about possible illness, but he denies being sick so she reluctantly lets him go upstairs. Dan, wearing a surgeon s mask, meets Melinda in her bedroom cleanroom and removes the mask to comply with her demand for a kiss. While kissing her, Dan notices urticaria on Melinda s left forearm, but when he tries to question the girl about it, she almost immediately goes into anaphylaxis . Mrs. Bardach saves her via the use of an EpiPen , blames Dan, and takes her to the hospital. There it is revealed that Melinda had a transplant heart operation after her chest was crushed in a car accident. Thus, with a compromised immune system she has to be kept in a constantly clean environment. Suspicions arise regarding whether Dan has been sneaking into her house. House and his team discover that the boy actually did meet Melinda, had sexual intercourse with her and, as a precaution for her safety, has been taking penicillin without realizing that t ... more details
on the body, recognition and treatment. There is a section on the use of an EpiPen , and opportunity to use a practice EpiPen. ref name Renfrew http www.firstaidrenfrew.org.uk courses.htm ... more details
Wikify date January 2011 Refimprove date August 2007 The son of a prominent surgeon and trained in surgery himself, Stanley Sarnoff produced over 200 papers and 60 patents during the course of his long career. His work included the development of such widely used devices as the auto injector , which was a precursor to the EpiPen , and the 24 hour cardiac monitor. In addition to his own work, he was devoted to philanthropy and, though the creation of The Stanley J Sarnoff Endowment for Cardiovascular Science, he has helped to inspire medical students and cardiology fellows from around the country to pursue cardiovascular research. Early life Stanley Sarnoff received his undergraduate degree from Princeton University 1938 and his medical degree form Johns Hopkins University School of Medicine 1942 . Although he was interested in research as a medical student, Sarnoff was strongly encouraged to become a cardiac surgeon by his father, Jacob Sarnoff, who was a prominent surgeon of the time. However, it was while Sarnoff was assisting his father in the operating room that he made observations which challenged conventional thoughts on cardiac physiology. The observations he made on that day would become the foundation of his bench research and revolutionize the way cardiology was practiced. His observations were so revolutionary that they infuriate his father to which Stanley, displaying the belief in scientific observation that would take him so far, would reply , Dad, I know what I saw. After his residency, Sarnoff completed post graduate training at Bellevue Hospital New York , Beth Israel Hospital Boston , Mount Sinai Hospital New York , and Harvard Medical School. The Academic After his training, Sarnoff spent a dozen years at the Harvard University School of Public Health 1948 1960 as an Assistant Professor of Physiology and he become Chief of the Laboratory of Cardiovascular Physiology at the National Heart Institute 1954 . It would be here, at the NIH, that Sarnoff ... more details
wins. Chris then gives each team walkie talkies and Gwen Cody s epipen, in case of an emergency ... hikes down a trail, Cody thanks Gwen for taking his epipen, but Gwen confesses that she has no idea ... tosses the epipen back to him in disgust. Suddenly, Cody is grabbed by an enormous mosquito ... in batteries . However, he cannot reach it. As a result, Gwen gets shot by the epipen and Courtney ... for Gwen, who is sound asleep due to Cody s epipen. Heather is confused for a goddess and her lost ... more details
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