Unreferenced stub auto yes date December 2009 File Formate.svg thumb 150px Structure of formateFormate or methanoate is the ion CHOO sup sup or HCOO sup sup formic acid minus one hydrogen ion . It is the simplest carboxylate anion . It is produced in large amounts in the hepatic liver cells mitochondria of embryonic cells and in cancer cells by the folate cycle source H Frederik Nijhout, et al, In silico experimentation with a model of hepatic mitochondrial folate metabolism, Theoretical Biology and Medical Modeling, 2006, 3 40, link http www.tbiomed.com content 3 1 40 abstract . A formate compound is a Salt chemistry salt or ester of formic acid . Examples ethyl formate , CH sub 3 sub CH sub 2 sub HCOO sodium formate , Na HCOO caesium formate, Cs HCOO see Caesium Petroleum exploration Caesium Petroleum exploration methyl formate , CH sub 3 sub HCOO methyl chloroformate , CH sub 3 sub OCOCl triethyl orthoformate trimethyl orthoformate , C sub 4 sub H sub 10 sub O sub 3 sub Category Carboxylate anions Category Formates Organic compound stub de Formiate es Formiato fr Formiate nl Formiaat ja pl Mr wczany pt Formiato ru sr Format so fi Formiaatti zh ... more details
enzyme Name formate kinase EC number 2.7.2.6 CAS number 9026 65 7 IUBMB EC number 2 7 2 6 GO code 0047900 image width caption In enzymology , a formate kinase EC number 2.7.2.6 is an enzyme that catalysis catalyzes the chemical reaction ATP formate math rightleftharpoons math ADP formyl phosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and formate , whereas its two product chemistry products are adenosine diphosphate ADP and formyl phosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with a carboxy group as acceptor. The systematic name of this enzyme class is ATP formate phosphotransferase . This enzyme participates in glyoxylate and dicarboxylate metabolism . References reflist 1 cite journal author Sly WS and Stadtman ER date 1963 title Formate metabolism. II. Enzymatic synthesis of formyl phosphate and formyl coenzyme A in Clostridium cylindrosporum journal J. Biol. Chem. volume 238 pages 2639&ndash 2647 enzyme stub Category EC 2.7.2 Category Enzymes of unknown structure ... more details
Pfam box Symbol Form deh trans Name Formate dehydrogenase N, transmembrane image width caption Pfam PF09163 InterPro IPR015246 SMART Prosite SCOP 1kqf TCDB OPM family OPM protein PDB PDB3 1kqf B 246 289 PDB3 1kqg B 246 289 Formate dehydrogenases are a set of enzyme s that catalyse the oxidation of formate to bicarbonate , donating the electrons to a second substrate, such as Nicotinamide adenine dinucleotide NAD sup sup in formate NAD oxidoreductase EC 1.2.1.2 or to a cytochrome in formate ferricytochrome b1 oxidoreductase EC 1.2.2.1 . ref cite journal author Ferry JG title Formate dehydrogenase journal FEMS Microbiol. Rev. volume 7 issue 3 4 pages 377 82 year 1990 pmid 2094290 ref Biological function NAD dependent formate dehydrogenases are important in methylotroph ic yeast and bacteria and are vital ... VS title NAD dependent formate dehydrogenase journal Biochem. J. volume 301 issue 3 pages 625 ... metabolism in prokaryotes. ref cite journal author Jormakka M, Byrne B, Iwata S title Formate .... coli , the formate ferricytochrome b1 oxidoreductase is an intrinsic membrane protein with two ... DH title The organization of formate dehydrogenase in the cytoplasmic membrane of Escherichia coli journal ... of specific formate dehydrogenase and cytochrome b1 components in nitrate reduction journal ... Formate NAD CO 2 NADH Cytochrome dependent reaction Formate 2 ferricytochrome b1 CO 2 2 ferrocytochrome ... family that sometimes employ tungsten bacterial formate dehydrogenase H is known to use a selenium ... Containing Formate Dehydrogenase H from Escherichia coli A Molybdopterin Enzyme That Catalyzes Formate ... subunit of formate dehydrogenase consists of a single transmembrane helix. This domain acts ... force generation structure of formate dehydrogenase N journal Science volume 295 issue 5561 pages 1863 1868 year 2002 pmid 11884747 doi 10.1126 science.1068186 ref See also Formate dehydrogenase cytochrome Formate dehydrogenase cytochrome c 553 Formate dehydrogenase NADP Microbial metabolism References ... more details
chembox verifiedrevid 477501961 Name Methyl formate ImageFileL1 Methyl formate.svg ImageSizeL1 100px ImageNameL1 Structural formula of methyl formate ImageFileR1 Methyl formate 3D balls.png ImageSizeR1 100px ImageNameR1 Ball and stick model of the methyl formate molecule IUPACName methyl methanoate Section1 Chembox Identifiers CASNo Ref cascite correct CAS CASNo 107 31 3 ChEMBL Ref ebicite correct EBI ChEMBL 295026 PubChem 7865 SMILES O COC ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 7577 InChI 1 C2H4O2 c1 4 2 3 h2H,1H3 InChIKey TZIHFWKZFHZASV UHFFFAOYAI StdInChI Ref stdinchicite correct chemspider StdInChI 1S C2H4O2 c1 4 2 3 h2H,1H3 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey TZIHFWKZFHZASV UHFFFAOYSA N Section2 Chembox Properties C 2 H 4 O 2 Density 0.98 g cm MeltingPtC 100 BoilingPtC 32 Section7 Chembox Hazards ExternalMSDS http msds.chem.ox.ac.uk ME methyl formate.html Oxford MSDS EUClass Highly flammable F Harmful Xn Methyl formate , also called ..., methyl formate can be produced by the condensation reaction of methanol and formic acid ... methyl formate, however, is usually produced by the combination of methanol and carbon monoxide ... companies gives 96 selectivity toward methyl formate, although it can suffer from catalyst sensitivity ..., US Patent US4216339 ref Uses Methyl formate is used primarily to manufacture formamide , dimethylformamide ... use of methyl formate, which sometimes brings it attention, was in refrigeration. Before the introduction of less toxic refrigerants, methyl formate was used as an alternative to sulfur dioxide in domestic refrigerators, such as some models of the famous GE Monitor Top. Owners of methyl formate ... SI&cMS on NIST Chemistry WebBook Methyl formate http www.chemicalland21.com arokorhi industrialchem organic METHYL 20FORMATE.htm ChemicalLand21.com entry on METHYL FORMATE DEFAULTSORT Methyl Formate Category Methyl esters Category Formate esters cs Methylester kyseliny mraven de Ameisens uremethylester ... more details
chembox verifiedrevid 414182160 Reference ref Olsen, J C editor , Van Nostrand s Chemical Annual , Chapman and Hall, London, 1934 ref ImageFile Potassium formate.png ImageSize 120px IUPACName Potassium formate OtherNames Section1 Chembox Identifiers CASNo Ref cascite CASNo 590 29 4 PubChem 2735122 RTECS LQ9625000 SMILES C O O. K Section2 Chembox Properties C 1 H 1 K 1 O 2 Appearance colorless crystals br deliquescent Density 1.908 g cm sup 3 sup MeltingPtC 167.5 BoilingPt Decomposes Solubility 32.8 g 100 mL 0 C br 331 g 100 mL 25 C br 657 g 100 mL 80 C SolubleOther soluble in alcohol br insoluble in ether pKb 10.25 Section3 Chembox Hazards MainHazards FlashPt Autoignition Potassium formate is the potassium salt chemistry salt of formic acid . It is an intermediate in the formate potash process for the production of potassium. ref Concise Encyclopedia Chemistry , Mary Eagleson 1994 , page 888. ISBN 978 3 11 011451 5 ref Potassium formate has also been studied as a potential environmentally friendly deicing salt for use on roads. ref cite journal author Pasi P. Hellst n, Jani M. Salminen, Kirsten S. J rgensen, and Taina H. Nyst n journal Environ. Sci. Technol. year 2005 volume 39 issue 13 pages 5095 5100 doi 10.1021 es0482738 pmid 16053115 title Use of potassium formate in road winter deicing can reduce groundwater deterioration. ref References Reflist Potassium compounds Category Formates Category Potassium compounds organic compound stub cs Mraven an draseln de Kaliumformiat nl Kaliumformiaat pl Mr wczan potasu ru fi Kaliumformiaatti sv Kaliumformiat zh ... more details
Chembox verifiedrevid 438202156 Reference ref http www.sigmaaldrich.com catalog ProductDetail.do?D7 0&N5 SEARCH CONCAT PNO BRAND KEY&N4 W219703 ALDRICH&N25 0&QS ON&F SPEC Isobutyl formate at Sigma Aldrich ref ImageFile isobutyl formate.svg ImageSize 180px IUPACName 2 Methylpropyl formate OtherNames Section1 Chembox Identifiers CASNo Ref cascite correct ?? CASNo 542 55 2 PubChem 10957 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 10492 SMILES O COCC C C StdInChI Ref stdinchicite correct chemspider StdInChI 1S C5H10O2 c1 5 2 3 7 4 6 h4 5H,3H2,1 2H3 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey AVMSWPWPYJVYKY UHFFFAOYSA N Section2 Chembox Properties C 5 H 10 O 2 Appearance Density 0.885 g mL MeltingPtC 98.4 BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt 10 C Autoignition RPhrases R11 R34 SPhrases S16 S26 S33 S36 37 39 S45 Isobutyl formate 2 methylpropyl methanoate is an organic ester with the chemical formula C sub 5 sub H sub 10 sub O sub 2 sub . It is formed by diluting isobutanol with methanoic acid , sulfuric acid can serve as a catalyst . It is used as a flavor and fragrance ingredient because of its odor which is sweet, ethereal, and slightly fruity. ref http www.thegoodscentscompany.com data rw1015121.html Isobutyl formate , The Good Scents Company ref ref cite journal author Mosciano, Gerard journal Perfumer & Flavorist volume 14 issue 6 pages 47 year 1989 ref References reflist ester stub Category Formate esters ... more details
chembox verifiedrevid 443743900 Name Ethyl formate ImageFileL1 Ethyl formate 2D skeletal B.png ImageSizeL1 100px ImageNameL1 Ethyl methanoate ImageFileR1 Ethyl formate 3D balls.png ImageSizeR1 120px IUPACName Ethyl formate SystematicName Ethyl methanoate Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 7734 UNII Ref fdacite correct FDA UNII 0K3E2L5553 InChI 1 C3H6O2 c1 2 5 3 4 h3H,2H2,1H3 InChIKey WBJINCZRORDGAQ UHFFFAOYAO ChEMBL Ref ebicite correct EBI ChEMBL 44215 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C3H6O2 c1 2 5 3 4 h3H,2H2,1H3 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey WBJINCZRORDGAQ UHFFFAOYSA N CASNo Ref cascite correct CAS CASNo 109 94 4 ChEBI Ref ebicite correct EBI ChEBI 52342 SMILES O COCC Section2 Chembox Properties C 3 H 6 O 2 Density 0.917 g cm sup 3 sup MeltingPtK 193 BoilingPtC 54.0 Ethyl formate is an ester formed when ethanol an alcohol reacts with formic acid a carboxylic acid . It is also known as ethyl methanoate because formic acid is also known as methanoic acid. Ethyl formate has the characteristic smell of rum and is also partially responsible for the flavor of Raspberry raspberries . ref name guardian cite news url http www.guardian.co.uk science 2009 apr 21 space raspberries amino acids astrobiology title Galaxy s centre tastes of raspberries and smells of rum, say astronomers last Sample first Ian date 21 April 2009 work The Guardian accessdate 2009 04 21 ref Exposure Ethyl ... Ethyl Formate title Alternative fumigants Ethyl Formate publisher University of California accessdate ... Safety and Health Administration OSHA , ethyl formate can irritate eyes, skin, mucous membrane ... title Occupational Safety and Health Guideline for Ethyl Formate publisher Occupational Safety and Health ... as the permissible exposure limit . In space Astronomers have identified ethyl formate in dust .... ref name guardian References references Category Ethyl esters Category Formate esters ... more details
chembox verifiedrevid 442344624 ImageFile Ammonium formate 2D.png ImageSize ImageFileL1 Ammonium 3D balls.png ImageSizeL1 90px ImageNameL1 Ball and stick model of the ammonium cation ImageFileR1 Formate 3D balls.png ImageNameR1 Ball and stick model of the formate anion IUPACName OtherNames Section1 Chembox Identifiers InChI 1 CH2O2.H3N c2 1 3 h1H, H,2,3 1H3 InChIKey VZTDIZULWFCMLS UHFFFAOYAT SMILES1 C O O.N StdInChI Ref stdinchicite correct chemspider StdInChI 1S CH2O2.H3N c2 1 3 h1H, H,2,3 1H3 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey VZTDIZULWFCMLS UHFFFAOYSA N CASNo Ref cascite correct CAS CASNo 540 69 2 PubChem 2723923 RTECS BQ6650000 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 10442 SMILES O CO.N Section2 Chembox Properties Formula NH sub 4 sub HCO sub 2 sub MolarMass 63.0559 g mol Appearance white monoclinic crystals br deliquescent Density 1.280 g cm sup 3 sup MeltingPt 116 C BoilingPt decomposes Solubility 102 g 100 mL 0 C br 143 g 100 mL 20 C br 531 g 100 mL 80 C SolubleOther soluble in liquid ammonia , alcohol and diethyl ether pkA 7 Section3 Chembox Hazards GHSPictograms GHSp GHS07 ref name sigma SigmaLink Productgroup Aldrich Productcode ... Ammonium formate , NH sub 4 sub HCO sub 2 sub , is the ammonium salt of formic acid . It is a colorless, hygroscopic , crystalline solid . Uses Pure ammonium formate decomposes into formamide and water ... by reacting ammonium formate with a dilute acid, and since ammonium formate is also produced from formic acid, it can serve as a way of storing formic acid. Ammonium formate can also be used in palladium on carbon Pd C reduction of functional groups. In the presence of Pd C, ammonium formate ... by hydrogens hydrogenolysis . Ammonium formate can be used for reductive amination of aldehydes and ketones Leuckart reaction Ammonium formate can be used as a buffer in high performance liquid ... acid and the ammonium ion are 3.8 and 9.2, respectively. Reactions When heated, ammonium formate ... more details
chembox Verifiedfields changed verifiedrevid 422111969 Name Sodium formate ImageFile Sodium formate 2D.png ImageSize 200px ImageName Structural formula of sodium formate ImageFileL1 Formate 3D balls.png ImageSizeL1 110px ImageNameL1 Ball and stick model of the formate anion ImageFileR1 Sodium 3D.png ImageNameR1 The sodium cation OtherNames formic acid, sodium salt Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 8517 ChEMBL Ref ebicite changed EBI ChEMBL 183491 UNII Ref fdacite correct FDA UNII 387AD98770 InChI 1 CH2O2.Na c2 1 3 h1H, H,2,3 q 1 p 1 InChIKey HLBBKKJFGFRGMU REWHXWOFAN SMILES Na . O C O StdInChI Ref stdinchicite correct chemspider StdInChI 1S CH2O2.Na c2 1 3 h1H, H,2,3 q 1 p 1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey HLBBKKJFGFRGMU UHFFFAOYSA M CASNo Ref cascite correct CAS CASNo 141 53 7 EINECS 205 488 0 Section2 Chembox Properties Formula HCOONa MolarMass 68.01 g mol Appearance white granules br deliquescent Density 1.92 g cm sup 3 sup 20 C Solubility 55 g 100 mL 20 C SolubleOther insoluble in ether br soluble in glycerol , alcohol MeltingPt 253 C BoilingPt decomposes pKa 7.0 8.5 0.1M Section7 Chembox Hazards EUClass not listed NFPA H 1 NFPA F NFPA R Sodium formate , HCOONa, is the sodium salt of formic acid , HCOOH. It usually appears as a white deliquescent powder. Uses Sodium formate is used in several fabric dyeing and printing processes. It is also used as a buffering agent for strong mineral acids to increase their pH , and as a food additive E237 . Preparation Sodium formate can be prepared in the laboratory by neutralizing formic acid with sodium carbonate . It can also be obtained by reacting ... out from the sodium formate solution, by Fractional crystallization chemistry fractional crystallization , than the soluble sodium chloride NaCl would be. For commercial use, sodium formate is produced ... CO sodium hydroxide NaOH HCOONa Sodium formate may also be created via the haloform reaction between ... more details
chembox Watchedfields changed verifiedrevid 444376086 Name Calcium formate Reference ref name hand Citation last Lide first David R. author link last2 first2 author2 link publication date date year 1998 title Handbook of Chemistry and Physics edition 87 volume series publication place Boca Raton, FL place publisher CRC Press id isbn 0 8493 0594 2 doi oclc pages 4 49 url accessdate ref ImageFile Calcium formate structure.png ImageSize ImageName Calcium formate OtherNames formic acid calcium salt, calcoform Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 10531 InChI 1 2CH2O2.Ca c2 2 1 3 h2 1H, H,2,3 q 2 p 2 SMILES Ca 2 . O C O. O C O InChIKey CBOCVOKPQGJKKJ NUQVWONBAS StdInChI Ref stdinchicite correct chemspider StdInChI 1S 2CH2O2.Ca c2 2 1 3 h2 1H, H,2,3 q 2 p 2 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey CBOCVOKPQGJKKJ UHFFFAOYSA L CASNo Ref cascite correct CAS CASNo 544 17 2 EINECS 208 863 7 KEGG Ref keggcite correct kegg KEGG C18586 PubChem 10997 RTECS LQ5600000 Section2 Chembox Properties Formula Ca HCOO sub 2 sub MolarMass 130.113 g mol ExactMass 129.9579 Appearance white powder Odor weak, caramel like odor Density 2.009 g cm sup 3 sup Solubility 16.1 g 100 mL 0 C br 16.6 g 100 mL 20 C br 18.4 g 100 mL 100 C MeltingPt decomposes at 300 C BoilingPt SolubleOther insoluble in alcohol Section7 Chembox Hazards EUClass not listed NFPA H 1 NFPA R 0 NFPA F 0 Section8 Chembox Related OtherAnions Calcium acetate OtherCations Sodium formate OtherFunctn Function OtherCpds Calcium formate , Ca HCOO sub 2 sub , is the calcium Salt chemistry salt of formic acid , HCOOH. It is also known as food additive E238 in food industry. The mineral form is very rare and called formicaite. It is known from a few boron deposits. It may be produced synthetically by reacting calcium oxide or calcium hydroxide with formic acid . References Reflist Organic compound stub Category Calcium compounds Category Formates ar ... more details
Chembox Watchedfields changed verifiedrevid 435175678 ImageFile ImageSize ImageAlt IUPACName OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 78394 StdInChI Ref stdinchicite correct chemspider StdInChI 1S 2CH2O2.2O.U c2 2 1 3 h2 1H, H,2,3 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey SFIHWLKHBCDNCE UHFFFAOYSA N CASNo Ref cascite correct ?? CASNo 16984 59 1 PubChem 86897 SMILES O CO.O CO.O U O Section2 Chembox Properties Formula UO sub 2 sub CHO sub 2 sub sub 2 sub H sub 2 sub O MolarMass Appearance fine yellow powder Density MeltingPt 110 C BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uranyl formate UO sub 2 sub CHO sub 2 sub sub 2 sub H sub 2 sub O is a fine yellow free flowing powder occasionally used in transmission electron microscopy . It is occasionally used as a 0.5 or 1 Aqueous solution aqueous negative stain in transmission electron microscopy TEM because it shows a finer grain structure than uranyl acetate . However, uranyl formate does not easily go into solution , and once dissolved, has a rather limited lifetime as a Staining stain . It is quite sensitive to light, especially ultraviolet light, and will Precipitation chemistry precipitate if exposed. See also electron microscope References http www.2spi.com catalog chem Uranyl Formate.shtml 2SPI.com , compound information, retrieved May 3, 2011. Uranium compounds Category Uranyl compounds Category Nuclear materials Category Formates Inorganic compound stub fr Formiate d uranyle ... more details
The Cl formate exchanger is a transport protein present in the kidney ref http www.pnas.org cgi content abstract 82 18 6362 Chloride Formate Exchange with Formic Acid Recycling A Mechanism of Active Chloride Transport across Epithelial Membranes Lawrence P. Karniski and Peter S. Aronson ref , where it functions in the renal chloride reabsorption . It is also present in vascular smooth muscle and cardiac muscle ref http circres.ahajournals.org cgi content abstract 74 1 48 Presence of chloride formate exchange in vascular smooth muscle and cardiac cells M Soleimani and RL Howard. Department of Medicine, Indiana University School of Medicine, Indianapolis 46202 5116. ref . The true molecular nature of the protein is unknown ref http www.pnas.org cgi reprint 141241098v1.pdf renal proximal tubule cells Identification of a chloride formate ... ref . References reflist Membrane transport proteins Ion pumps Category Transport proteins ... more details
enzyme Name formate C acetyltransferase EC number 2.3.1.54 CAS number 9068 08 0 IUBMB EC number 2 3 1 54 GO code 0008861 image width caption In enzymology , a formate C acetyltransferase EC number 2.3.1.54 is an enzyme that catalysis catalyzes the chemical reaction acetyl CoA formate math rightleftharpoons math CoA pyruvate Thus, the two substrate biochemistry substrates of this enzyme are acetyl CoA and formate , whereas its two product chemistry products are coenzyme A CoA and pyruvate . This enzyme belongs to the family of transferase s, specifically those acyltransferase s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl CoA formate C acetyltransferase . Other names in common use include pyruvate formate lyase , pyruvic formate lyase , and formate acetyltransferase . This enzyme participates in 3 metabolism metabolic pathways pyruvate metabolism , propanoate metabolism , and butanoate metabolism . Structural studies As of late 2007, 8 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1CM5 , PDB link 1H16 , PDB link 1H17 , PDB link 1H18 , PDB link 1MZO , PDB link 1QHM , PDB link 2PFL , and PDB link 3PFL . References reflist 1 cite journal author Knappe J, Blaschkowski HP, Grobner P, Schmitt T date 1974 title Pyruvate formate lyase of Escherichia coli the acetyl enzyme intermediate journal Eur. J. Biochem. volume 50 pages 253&ndash 63 pmid 4615902 doi 10.1111 j.1432 1033.1974.tb03894.x issue 1 transferase stub Category EC 2.3.1 Category Enzymes of known structure it Formato C acetiltransferasi ... more details
enzyme Name formate dihydrofolate ligase EC number 6.3.4.17 CAS number 123303 25 3 IUBMB EC number 6 3 4 17 GO code 0047897 image width caption In enzymology , a formate dihydrofolate ligase EC number 6.3.4.17 is an enzyme that catalysis catalyzes the chemical reaction ATP formate dihydrofolate math rightleftharpoons math ADP phosphate 10 formyldihydrofolate The 3 substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP , formate , and dihydrofolate , whereas its 3 product chemistry products are adenosine diphosphate ADP , phosphate , and 10 formyldihydrofolate . This enzyme belongs to the family of ligase s, specifically those forming generic carbon nitrogen bonds. The systematic name of this enzyme class is formate dihydrofolate ligase ADP forming . Other names in common use include formyltransferase, dihydrofolate , dihydrofolate formyltransferase , and formyl dihydrofolate synthase . References reflist 1 Further reading refbegin cite journal author Drake JC, Baram J, Allegra CJ date 1990 title Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF 7 breast cancer cells journal Biochem. Pharmacol. volume 39 pages 615&ndash 8 pmid 2306274 doi 10.1016 0006 2952 90 90073 T issue 3 refend ligase stub Category EC 6.3.4 Category Enzymes of unknown structure ... more details
enzyme Name formate dehydrogenase cytochrome EC number 1.2.2.1 CAS number IUBMB EC number 1 2 2 1 GO code 0047898 image width caption In enzymology , a formate dehydrogenase cytochrome EC number 1.2.2.1 is an enzyme that catalysis catalyzes the chemical reaction formate 2 ferricytochrome b sub 1 sub math rightleftharpoons math CO sub 2 sub 2 ferrocytochrome b sub 1 sub 2 H sup sup Thus, the two substrate biochemistry substrates of this enzyme are formate and ferricytochrome b1 , whereas its 3 product chemistry products are carbon dioxide CO sub 2 sub , ferrocytochrome b1 , and hydrogen ion H sup sup . This enzyme belongs to the family of oxidoreductase s, specifically those acting on the aldehyde or oxo group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is formate ferricytochrome b1 oxidoreductase . Other names in common use include formate dehydrogenase , and formate cytochrome b1 oxidoreductase . This enzyme participates in glyoxylate and dicarboxylate metabolism . References reflist 1 cite journal author Gale EF date 1939 title Formic dehydrogenase of Bacterium coli its inactivation by oxygen and its protection in the bacterial cell journal Biochem. J. volume 33 pages 1012&ndash 1027 1.2 enzyme stub Category EC 1.2.2 Category Enzymes of unknown structure it Formato deidrogenasi citocromo ja ... more details
enzyme Name formate dehydrogenase cytochrome c 553 EC number 1.2.2.3 CAS number IUBMB EC number 1 2 2 3 GO code 0047111 image width caption In enzymology , a formate dehydrogenase cytochrome c 553 EC number 1.2.2.3 is an enzyme that catalysis catalyzes the chemical reaction formate ferricytochrome c 553 math rightleftharpoons math CO sub 2 sub ferrocytochrome c 553 Thus, the two substrate biochemistry substrates of this enzyme are formate and ferricytochrome c 553 , whereas its two product chemistry products are carbon dioxide CO sub 2 sub and ferrocytochrome c 553 . This enzyme belongs to the family of oxidoreductase s, specifically those acting on the aldehyde or oxo group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is formate ferricytochrome c 553 oxidoreductase . References reflist 1 cite journal author Yagi T date Tokyo title Formate cytochrome oxidoreductase of Desulfovibrio vulgaris journal J. volume Biochem. pages 473&ndash 8 pmid 4982127 issue 4 cite journal author Yagi T date 1979 title Purification and properties of cytochrome c 553, an electron acceptor for formate dehydrogenase of Desulfovibrio vulgaris, Miyazaki journal Biochim. Biophys. Acta. volume 548 pages 96&ndash 105 pmid 226135 issue 1 1.2 enzyme stub Category EC 1.2.2 Category Enzymes of unknown structure it Formato deidrogenasi citocromo c 553 ja c 553 ... more details
enzyme Name formate dehydrogenase NADP EC number 1.2.1.43 CAS number 51377 43 6 IUBMB EC number 1 2 1 43 GO code 0047899 image width caption In enzymology , a formate dehydrogenase NADP EC number 1.2.1.43 is an enzyme that catalysis catalyzes the chemical reaction formate NADP sup sup math rightleftharpoons math CO sub 2 sub NADPH Thus, the two substrate biochemistry substrates of this enzyme are formate and nicotinamide adenine dinucleotide phosphate NADP sup sup , whereas its two product chemistry products are carbon dioxide CO sub 2 sub and nicotinamide adenine dinucleotide phosphate NADPH . This enzyme belongs to the family of oxidoreductase s, specifically those acting on the aldehyde or oxo group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is formate NADP oxidoreductase . Other names in common use include NADP dependent formate dehydrogenase , and formate dehydrogenase NADP . This enzyme participates in methane metabolism . It has 3 cofactor biochemistry cofactors iron , Tungsten , and Selenium . Structural studies As of late 2007, only one tertiary structure structure has been solved for this class of enzymes, with the Protein Data Bank PDB accession code PDB link 2GSD . References reflist 1 cite journal author Andreesen JR, Ljungdahl LG date 1974 title Nicotinamide adenine dinucleotide phosphate dependent formate dehydrogenase from Clostridium thermoaceticum purification and properties journal J. Bacteriol. volume 120 pages 6&ndash 14 pmid 4154039 issue 1 pmc 245723 cite journal author Yamamoto I, Saiki T, Liu SM, Ljungdahl LG date 1983 title Purification and properties of NADP dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten selenium iron protein journal J. Biol. Chem. volume 258 pages 1826&ndash 32 pmid 6822536 issue 3 1.2 enzyme stub Category EC 1.2.1 Category NADPH dependent enzymes Category Iron enzymes Category Tungsten enzymes Category Selenium enzymes Category Enzymes of known structure it Formato ... more details
Merge Formate C acetyltransferase date October 2009 Image with unknown copyright status removed Image PDBpicPFL.jpg thumb Pyruvate formate lyase drawn from PDB 1QHM . Pyruvate formate lyase PFL EC number ... the reversible conversion of pyruvate and coenzyme A into formate and acetyl CoA . The reaction occurs as follows Image PFL reaction.jpg Structure Pyruvate formate lyase is a homodimer made of 85 kDa ... Studies have found structural similarities between the active site of pyruvate formate lyase and that of Class ... formate lyase begins with radical transfer from Gly734 to Cys418, via Cys419. The Cys418 ... hydrogen atom transfer with Cys419. This generates formate and a Cys419 radical. coenzyme ... behind a Cys418 radical. Pyruvate formate lyase can then undergo radical transfer to put the radical ... with unknown copyright status removed Image PFL mechanism.jpg Proposed pyruvate formate lyase mechanism ... states of pyruvate formate lyase to regulate anaerobic glucose metabolism PFL activase AE and PFL deactivase DA . Activated pyruvate formate lyase allows formation of acetyl CoA, a small molecule important in the production of energy, when pyruvate is available. Deactivated pyruvate formate lyase ... superfamily. The enzyme turns pyruvate formate lyase on by converting Gly734 G H into a Gly734 ... PFL deactivase DA turns pyruvate formate lyase off by quenching the Gly734 radical. sup 5 sup Furthermore, pyruvate formate lyase is sensitive to molecular oxygen O sub 2 sub , the presence of which ... S. , Volker wagner A.F. Structure and mechanism of the glycyl radical enzyme pyruvate formate ... formate lyase in complex with pyruvate and CoA. How the enzyme uses the Cys 418 thiyl radical for pyruvate ..., J. Adenosylmethionine dependent synthesis of the glycyl radical in pyruvate formate lyase by abstraction ... M.C. , Ollis D.L. , Wong K.K. , Kozarich J.W. , Goldman A. Pyruvate formate lyase is structurally ..., Y., Broderick, JB. Inactivation of E. coli pyruvate formate lyase role of AdhE and small molecules ... more details
enzyme Name formate tetrahydrofolate ligase EC number 6.3.4.3 CAS number 9023 66 9 IUBMB EC number 6 3 4 3 GO code 0004329 image width caption Infobox protein family Symbol FTHFS Name Formate tetrahydrofolate ligase image PDB 1eg7 EBI.jpg width caption the crystal structure of formyltetrahydrofolate synthetase from moorella thermoacetica Pfam PF01268 Pfam clan CL0023 InterPro IPR000559 SMART PROSITE PDOC00595 MEROPS SCOP 1fpm TCDB OPM family OPM protein CAZy CDD In enzymology , a formate tetrahydrofolate ligase EC number 6.3.4.3 is an enzyme that catalysis catalyzes the chemical reaction ATP formate tetrahydrofolate math rightleftharpoons math ADP phosphate 10 formyltetrahydrofolate The 3 substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP , formate , and tetrahydrofolate , whereas its 3 product chemistry products are adenosine diphosphate ADP , phosphate , and 10 formyltetrahydrofolate . This enzyme belongs to the family of ligase s, specifically those forming generic carbon nitrogen bonds. This enzyme participates in glyoxylate and dicarboxylate metabolism and one carbon pool by folate . In eukaryotes the FTHFS activity is expressed by a multifunctional enzyme, C 1 tetrahydrofolate synthase C1 THF synthase , which also catalysis catalyses the dehydrogenase and cyclohydrolase activities. Two forms of C1 THF synthases are known, one is located in the mitochondrial matrix , while the second one is cytoplasm cytoplasmic . ref name pmid2836393 cite journal author Shannon KW, Rabinowitz JC title Isolation and characterization of the Saccharomyces cerevisiae MIS1 gene encoding mitochondrial C1 tetrahydrofolate synthase journal J. Biol. Chem. volume 263 ... doi 10.1021 bi00476a007 url ref Nomenclature The systematic name of this enzyme class is formate tetrahydrofolate .... Examples Human genes encoding formate tetrahydrofolate ligases include MTHFD1 cytoplasmic MTHFD1L mitochondrial ... of the formate activating enzyme from Micrococcus aerogenes journal J. Biol. Chem. volume 234 pages ... more details
enzyme Name formate C acetyltransferase activating enzyme EC number 1.97.1.4 CAS number 206367 15 9 IUBMB EC number 1 97 1 4 GO code 0043365 image width caption In enzymology , a formate C acetyltransferase activating enzyme EC number 1.97.1.4 is an enzyme that catalysis catalyzes the chemical reaction S adenosyl L methionine dihydroflavodoxin formate C acetyltransferase glycine math rightleftharpoons math 5 deoxyadenosine L methionine flavodoxin semiquinone formate C acetyltransferase glycin 2 yl radical The 3 substrate biochemistry substrates of this enzyme are S adenosyl L methionine , dihydroflavodoxin , and formate C acetyltransferase glycine , whereas its 4 product chemistry products are 5 deoxy adenosine , L methionine , flavodoxin semiquinone , and formate C acetyltransferase glycin 2 yl radical. This enzyme belongs to the family of oxidoreductase s. The systematic name of this enzyme class is formate C acetyltransferase glycine dihydroflavodoxin S adenosyl L methionine oxidoreductase S adenosyl L methionine cleaving . Other names in common use include PFL activase , PFL glycine S adenosyl L methionine H transferase flavodoxin oxidizing, S adenosyl L methionine cleaving , formate acetyltransferase activating enzyme , formate acetyltransferase glycine dihydroflavodoxin S adenosyl L methionine oxidoreductase S adenosyl L methionine cleaving . References reflist 1 cite journal author Frey M, Rothe M, Wagner AF, Knappe J date 1994 title Adenosylmethionine dependent synthesis of the glycyl radical in pyruvate formate lyase by abstraction of the glycine C 2 pro S hydrogen atom. Studies of 2H glycine substituted enzyme and peptides homologous to the glycine 734 site journal J. Biol. Chem. volume 269 pages 12432&ndash 7 pmid 8175649 issue 17 cite journal author Wagner AF, Frey M, Neugebauer FA, Schafer W, Knappe J date 1992 title The free radical in pyruvate formate lyase ... pmid 11395404 doi 10.1146 annurev.biochem.70.1.121 DEFAULTSORT Formate C acetyltransferase activating ... more details
DISPLAYTITLE C sub 5 sub H sub 10 sub O sub 2 sub The molecular formula C sub 5 sub H sub 10 sub O sub 2 sub molar mass 102.13 g mol may refer to tert Butyl formate tert Butyl formate Isopropyl acetate Isovaleric acid Methyl butyrate Pivalic acid Propyl acetate Valeric acid MolFormDisambig el C5H10O2 fr C5H10O2 ... more details
enzyme Name lactate aldolase EC number 4.1.2.36 CAS number 110777 33 8 IUBMB EC number 4 1 2 36 GO code 0050041 image width caption In enzymology , a lactate aldolase EC number 4.1.2.36 is an enzyme that catalysis catalyzes the chemical reaction S lactate math rightleftharpoons math formate acetaldehyde Hence, this enzyme has one substrate biochemistry substrate , S lactate , and two product chemistry products , formate and acetaldehyde . This enzyme belongs to the family of lyase s, specifically the aldehyde lyases, which cleave carbon carbon bonds. The systematic name of this enzyme class is S lactate acetaldehyde lyase formate forming . Other names in common use include lactate synthase , and S lactate acetaldehyde lyase . This enzyme participates in pyruvate metabolism . References reflist 1 cite journal author Gulyi MF, Silonova NV date 1987 title Various metabolic reactions of formate in animal tissues journal Ukr. Biokhim. Zh. volume 59 pages 29&ndash 35 pmid 3629727 issue 4 4.1 enzyme stub Category EC 4.1.2 Category Enzymes of unknown structure ... more details
enzyme Name formyl CoA hydrolase EC number 3.1.2.10 CAS number 9025 91 6 IUBMB EC number 3 1 2 10 GO code 0047901 image width caption In enzymology , a formyl CoA hydrolase EC number 3.1.2.10 is an enzyme that catalysis catalyzes the chemical reaction formyl CoA H sub 2 sub O math rightleftharpoons math CoA formate Thus, the two substrate biochemistry substrates of this enzyme are formyl CoA and water H sub 2 sub O , whereas its two product chemistry products are coenzyme A CoA and formate . This enzyme belongs to the family of hydrolase s, specifically those acting on thioester bonds. The systematic name of this enzyme class is formyl CoA hydrolase . This enzyme is also called formyl coenzyme A hydrolase . This enzyme participates in glyoxylate and dicarboxylate metabolism . References reflist 1 cite journal author Sly WS and Stadtman ER date 1963 title Formate metabolism. I. Formyl coenzyme A, an intermediate in the formate dependent decomposition of acetyl phosphate in Clostridium kluyveri journal J. Biol. Chem. volume 238 pages 2632&ndash 2638 hydrolase stub Category EC 3.1.2 Category Enzymes of unknown structure ... more details
Clerici may refer to People Carlo Clerici , Swiss bicycle racer Gianfranco Clerici , Italian screenwriter Gianni Clerici , Italian tennis player and commentator Sergio Clerici , Brazilian footballer Other Clerici solution , a solution of thallium formate and thallium malonate in water dab de Clerici it Clerici ... more details
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