Unreferenced date July 2010 In bioinformatics, hybrid genome assembly refers to a genome assembly merging different DNA sequencing technologies. Category Genome projects bioinformatics stub ... more details
The Cancer Genome Project , based at the Wellcome Trust Sanger Institute , aims to identify genetic variation sequence variant s mutation s critical in the development of human cancer s. Like The Cancer Genome Atlas project within the United States, the Cancer Genome Project represents an effort in the War on Cancer to improve cancer diagnosis, treatment, and prevention through a better understanding of the molecular basis of this disease. The Cancer Genome Project, led by Michael Stratton and Andy Futreal, combines knowledge of the human genome sequence with high throughput screening high throughput mutation detection techniques. See also Cancer genome sequencing The Cancer Genome Atlas and http cgap.nci.nih.gov The Cancer Genome Anatomy Project ref http www.cancer.gov cancertopics understandingcancer CGAP ref ref http www.ncbi.nlm.nih.gov ncicgap ref at the National Cancer Institute. International Cancer Genome Consortium COSMIC cancer database External links http www.sanger.ac.uk genetics CGP Cancer Genome Project Official website http www.sciam.com article.cfm?id mapping the cancer genome Francis S. Collins and Anna D. Barker. Mapping the Cancer Genome . Scientific American, February 2007 References references Wellcome Trust genetics stub oncology stub sci org stub UK med org stub Category Human genome projects Category Wellcome Trust Category Cancer genome databases pt Projeto Genoma do C ncer ... more details
The Human Genome Organisation HUGO is an organization involved in the Human Genome Project , a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world. The HUGO Gene Nomenclature Committee HGNC , sometimes referred to as HUGO , is one of HUGO s most active committees and aims to assign a unique gene name and symbol to each human gene. See also HUGO Gene Nomenclature Committee Celera Genomics Victor A. McKusick Ira Carmen List of genetics research organizations International Mammalian Genome Society External links http www.hugo international.org HUGO homepage http www.genenames.org HGNC homepage Category Genetics organizations sci org stub genetics stub ca Human Genome Organisation de Human Genome Organisation es Human Genome Organisation fr Human Genome Organisation it Human Genome Organization no Human Genome Organisation ru sr Organizacija za ljudski genom sv Human Genome Organisation ur zh ... more details
Cleanup date February 2009 In the fields of bioinformatics and computational biology, Genome Survey Sequences GSS are primary structure nucleotide sequences similar to expressed sequence tag EST s, with the exception that most of them are Genome genomic in origin, rather than mRNA . The name comes from the homonym National Center for Biotechnology Information NCBI GenBank division, which contains but is not limited to the following types of data random single pass read genome survey sequences cosmid BAC YAC end sequences exon trapped genomic sequences Alu Polymerase chain reaction PCR sequences transposon tagged sequences Genome Survey Sequences are typically generated and submitted to NCBI by labs performing genome sequencing and are used, amongst other things, as a framework for the mapping and sequencing of genome size pieces included in the standard GenBank divisions. References http www.ncbi.nlm.nih.gov dbGSS The Genome Survey Sequences Database homepage ftp ftp.ncbi.nih.gov genbank release.notes gb96.release.notes GenBank Flat File 96.0 Release Notes Category Bioinformatics ... more details
The Animal Genome Size Database is a comprehensive catalogue of published genome size estimates for vertebrate and invertebrate animal s. It was created in 2001 by T. Ryan Gregory Dr. T. Ryan Gregory of the University of Guelph in Canada. As of September 2005, the database contains data for over 4,000 species of animals. A similar database , the Plant DNA C values Database C value being analogous to genome size in diploid organisms was created by researchers at the Royal Botanic Gardens, Kew , in 1997. External links http www.genomesize.com Animal Genome Size Database http www.rbgkew.org.uk cval homepage.html Plant DNA C values Database http www.zbi.ee fungal genomesize index.php Fungal Genome Size Database http www.genomesize.com cellsize Cell Size Database Category Genetics Category Biological databases Category Biology websites genetics stub ... more details
The Genome Reference Consortium GRC is a group of educational institutes which was formed to improve the representation of reference genome s. At the time the Human Genome Project human reference was initially described, it was clear that some regions were wiktionary recalcitrant recalcitrant to closure with existing technology. The main reason for improving the reference assembly reference assemblies are that they are the cornerstones upon which all whole genome studies are based i.e. the 1000 Genomes Project . Initially the focus lies with the Human and the Mouse reference genomes with additional model organisms to be added at a later time. The goal of the Consortium is to correct the small number of regions in the reference that are currently misrepresented, to close as many remaining gap genetics gaps as possible and to produce alternative assemblies of structurally variant Locus genetics loci when necessary. External links http genomereference.org Genome Reference Consortium Members http www.ebi.ac.uk The European Bioinformatics Institute http genome.wustl.edu The Genome Institute at Washington University http www.ncbi.nlm.nih.gov The National Center for Biotechnology Information http www.sanger.ac.uk sequencing grc The Wellcome Trust Sanger Institute Wellcome Trust Category Genome projects Category Consortia Category Wellcome Trust ... more details
infobox biodatabase title Bovine Genome Database logo File Database.png description integrated tools for genome annotation scope organism Cattle center Georgetown University laboratory author pmid PMID 21123190 released standard format url http BovineGenome.org download webservice sql sparql webapp standalone license versioning frequency curation bookmark version The Bovine Genome Database is an integrated database for the bovine genome . ref cite journal quotes yes last Childers first Christopher P authorlink coauthors Reese Justin T, Sundaram Jaideep P, Vile Donald C, Dickens C Michael, Childs Kevin L, Salih Hanni, Bennett Anna K, Hagen Darren E, Adelson David L, Elsik Christine G year 2011 month Jan title Bovine Genome Database integrated tools for genome annotation and discovery journal Nucleic Acids Res. volume 39 issue Database issue pages D830 4 publisher location England issn pmid 21123190 doi 10.1093 nar gkq1235 bibcode oclc id url language eng format accessdate laysummary laysource laydate quote ref References references See also bovine genome External links http BovineGenome.org Biodatabase stub Category Biological databases Category Cattle ... more details
UCSC Malaria Genome Browser ref cite journal author Chakrabarti K. year 2007 title Structural RNAs of known and unknown function identified in malaria parasites by comparative genomics and RNA analysis journal RNA volume 13 pages 923 39 doi 10.1261 rna.751807 url http rnajournal.cshlp.org content 13 11 1923 pmid 17901154 last2 Pearson first2 M last3 Grate first3 L last4 Sterne Weiler first4 T last5 Deans first5 J last6 Donohue first6 JP last7 Ares Jr first7 M issue 11 pmc 2040097 ref is a bioinformatic research tool to study the malaria genome, developed by Hughes Undergraduate Research Laboratory together with the laboratory of Prof. Manuel Ares Jr. at the University of California, Santa Cruz . The web interface and database structure is based on the UCSC Biological database Genome Browser ref cite journal author Mangan, M., Williams J., Lathe, S., Karolchik, D., Lathe, W. year 2008 title UCSC genome browser deep support for molecular biomedical research. journal Biotechnology Annual Review volume 14 pages 63 108 doi 10.1016 S1387 2656 08 00003 3 pmid 18606360 ref ref cite journal author Kuhn, R. et al. year 2009 title The UCSC Genome Browser Database update 2009 journal Nucleic Acids ... abstract 37 suppl 1 D755 pmid 18996895 issue Database issue pmc 2686463 ref . UCSC Malaria Genome ... of the malaria parasite s genome, enter their own sequence data and notes, and compare findings across species. The Malaria Genome Browser also supports text and sequence based searches that provide quick, precise access to any region of specific interest in the malaria genome. This site contains the reference genome sequence and working draft assembly for Plasmodium falciparum from PlasmoDB PlasmoDb ref http www.plasmodb.org ref , the Plasmodium genome database build 5.0. External links http areslab.ucsc.edu UCSC Malaria Genome Browser http genome.ucsc.edu UCSC Genome Browser for human, vertebrate ... ucsc ucsc home.shtml UCSC Genome Browser tutorials References Reflist genetics stub Category ... more details
Wikify date January 2012 mergeto Mouse Genome Database date April 2012 unreferenced date November 2008 The Mouse Genome Informatics MGI website is hosted by The Jackson Laboratory . According to http www.informatics.jax.org mgihome projects aboutmgi.shtml their site , MGI provides integrated access to data on the genetics, genomics and biology of the laboratory mouse . External links http www.informatics.jax.org The MGI home page cite conference author Qi D, Blake JA, Kadin JA, Richardson JE, Ringwald M, Eppig JT, Bult CJ title Data integration in the mouse genome informatics MGI database conference Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE pages 37 8 date 8 11 August 2005 isbn 0 7695 2442 7 doi 10.1109 CSBW.2005.48 url http ieeexplore.ieee.org xpls abs all.jsp?arnumber 1540530 http www.informatics.jax.org mgihome other publications.shtml Mouse Genome Informatics Publications cite journal author Shaw D title Searching the Mouse Genome Informatics MGI resources for information on mouse biology from genotype to phenotype journal Curr Protoc Bioinformatics volume Chapter 1 pages Unit 1.7 year 2004 month May pmid 18428715 doi 10.1002 0471250953.bi0107s05 Category Mice Category Genetics bioinformatics stub de Mouse Genome Informatics sr ... more details
Infobox Organization name Floral Genome Project image image border size caption map msize mcaption motto formation 2001 type Academic Research headquarters Penn State University br University of Florida br Cornell University location flagicon USA United States membership language leader title leader name key people num staff budget website http fgp.bio.psu.edu Official website The Floral Genome Project is a collaborative research cooperation primarily between Penn State University , University of Florida , and Cornell University . The initial funding came from a grant of 7.4 million from the National Science Foundation . The Floral Genome Project was initiated to bridge the genomic gap between the most broadly studied plant model systems. According to the http www.floralgenome.org website , the following are the aims of the project blockquote The Floral Genome Project will investigate the origin, conservation, and diversification of the genetic architecture of the flower, and develop conceptual and real tools for evolutionary functional genomics in plants. blockquote External links http fgp.bio.psu.edu Official Website University of Florida Cornell University Category Genome projects Category Botany Category University of Florida Category Cornell University botany stub pl Floral Genome Project ... more details
The Africa Genome Education Institute AGEI is a public forum focusing on genetics and biotechnology in the African continent. It has organised major genome related events and conferences in Stellenbosch 2003 , Cairo 2004 , Nairobi 2005 , Somerset West 2006 . The AGEI s executive director is Prof Wilmot James . ref cite web url http www.africagenome.com index.php?option com content&view article&id 14&Itemid 32 title Institute Staff ref References references Category Science and technology in Africa sci org stub ... more details
saved book title subtitle cover image cover color Medical Genome analysis statistics Statistical hypothesis testing Null hypothesis Type I and type II errors Student s t test Analysis of variance F test ... more details
notability Companies date November 2011 Genome Research Foundation also known as Genome Foundation is a non profit research foundation and institute in Korea under the approval of the ministry of Education, Science, and Technology of Korea. It is a public research foundation with over 30 researchers and staff in 2011. GRF was established on 19 April 2010 and since then it has taken research in genomics and bioinformatics . Its main research institute is PGI Personal Genomics Institute which performs research in genomics area for the general public and by the general public. External links http genomefoundation.org Genome Research Foundation home page Category Genomics ... more details
Mouse Genome Conference, held near Heraklion, Crete The International Mammalian Genome Society IMGS ... genetic and genomic study of mammals. It has a scientific journal , Mammalian Genome , and organizes an annual international Academic conference meeting , the International Mammalian Genome Conference ... author title The International Mammalian Genome Society journal Mamm. Genome volume 1 issue 1 ... the organization of genetic data for example, into genetic map s and reference genome s , and To coordinate the mapping and sequencing of model organism s with Human Genome Project similar efforts focusing on the human genome . The society has served as an organizing body for a number of initiatives ... , an effort to assign a function to every gene in the mammalian genome, ref name pmid11233449 cite journal author Nadeau JH title Sequence interpretation. Functional annotation of mouse genome sequences ... database developments. ref name pmid1351872 Membership of the International Mammalian Genome ... they receive voting rights and access to Mammalian Genome . ref name bylaws The society is governed ... International Mammalian Genome Society date December 01, 2010 url http imgs.org committee.shtml ... Mammalian Genome Society work publisher International Mammalian Genome Society date December ... Genome File 2000px Jan Klein by Dorothea Bylica Academic bulletin Academy Sciences Czech Republic.JPEG thumb right Jan Klein , a founding editor of Mammalian Genome The IMGS has an official peer review ed journal, Mammalian Genome , which was launched with the society in 1991 but published and managed ... as the journal s first editors. ref name MG cite journal author title Mammalian Genome journal Mamm. Genome volume 1 issue 1 pages 1 1 year 1991 pmid doi 10.1007 BF00350840 url http www.springerlink.com ... Jan ref Mammalian Genome currently accepts both original and review articles on experimental, theoretical ... description cite web url http www.springer.com life sci cell biology journal 335 title Mammalian Genome ... more details
Orphan date January 2011 infobox biodatabase title cBARBEL logo File Database.png description The catfish genome database scope organism Ictalurus center laboratory author pmid PMID 20935046 released 2010 standard format url http catfishgenome.org download webservice sql sparql webapp BLAST standalone license versioning frequency curation bookmark version The catfish genome database cBARBEL is a database for the genetics of Ictalurus spp. ref cite journal quotes yes last Lu first Jianguo authorlink coauthors Peatman Eric, Yang Qing, Wang Shaolin, Hu Zhiliang, Reecy James, Kucuktas Huseyin, Liu Zhanjiang year 2011 month Jan title The catfish genome database cBARBEL an informatic platform for genome biology of ictalurid catfish journal Nucleic Acids Res. volume 39 issue Database issue pages D815 21 publisher location England issn pmid 20935046 doi 10.1093 nar gkq765 bibcode oclc id url language eng format accessdate laysummary laysource laydate quote ref References references External links http catfishgenome.org DEFAULTSORT Catfish Genome Database Category Biological databases Category Genomics Category Ictalurus Biodatabase stub ... more details
The Vertebrate and Genome Annotation Vega project provides manual curation of vertebrate genomes for the scientific community. ref cite journal author Ashurst JL, Chen CK, Gilbert JG, et al. title The Vertebrate Genome Annotation Vega database journal Nucleic Acids Research volume 33 issue Database issue pages D459 65 year 2005 month January pmid 15608237 pmc 540089 doi 10.1093 nar gki135 ref The Vega data repository is publicly available, regularly updated and includes Genome project Genome annotation annotations of several finished vertebrate genome sequences. ref cite journal author Loveland J title VEGA, the genome browser with a difference journal Briefings in Bioinformatics volume 6 issue 2 pages 189 93 year 2005 month June pmid 15975227 doi 10.1093 bib 6.2.189 ref Human, mouse and zebrafish are in the process of being completely annotated, whereas for other species the annotation is only of specific genomic regions of particular biological interest ref http vega.sanger.ac.uk Vega website homepage, retrieved 2012 02 21 ref . The Vega website is built upon the Ensembl codebase. ref cite journal author Searle SM, Gilbert J, Iyer V, Clamp M title The otter annotation system journal Genome Research volume 14 issue 5 pages 963 70 year 2004 month May pmid 15123593 pmc 479127 doi 10.1101 gr.1864804 ref The Vega database is run and developed by the Wellcome Trust Sanger Institute . References reflist External links http vega.sanger.ac.uk Vega homepage Category Bioinformatics Category Biological databases bioinformatics stub ... more details
Cancer genome sequencing is the whole genome sequencing of a single, homogeneous or heterogeneous group ... of the DNA or RNA sequences of cancer cell s . Unlike whole genome WG sequencing which is typically from blood cells, such as J. Craig Venter s ref name Venter Genome and James D. Watson s WG sequencing projects, ref name Watson Genome saliva, epithelial cells or bone cancer genome sequencing involves ... such as fibroblast stromal cells, or metastatic tumor sites. Similar to whole genome sequencing ... translocations and fusion gene s. Cancer genome sequencing is not limited to WG sequencing and can ... Historically, cancer genome sequencing efforts has been divided between transcriptome based sequencing projects and DNA centered efforts. The Cancer Genome Anatomy Project CGAP was first funded in 1997 .... ref name hccgp website The Wellcome Trust Sanger Institute Sanger Institute s Cancer Genome Project ... in cancer, ref name cancer gene census and a number of whole genome resequencing screens for genes implicated in cancer. ref name cgp webpage The International Cancer Genome Consortium ICGC ... of all these changes can be accomplished through various cancer genome sequencing strategies. The power of cancer genome sequencing lies in the heterogeneity of cancers and patients ... between a cancer subtype in one individual to the another individual. Cancer genome sequencing will allow ... aml paper These cellular factions could only have been identified through cancer genome sequencing ... cancer characterization in individuals, heavily involving sequencing include the Cancer Genome Project , based at the Wellcome Trust Sanger Institute and the Cancer Genome Atlas funded by the National Cancer Institute NCI and the National Human Genome Research Institute NHGRI . Combined with these efforts, the International Cancer Genome Consortium a larger body organization, is a voluntary scientific ... researchers. Cancer Genome Project CGP The Cancer Genome Projects goal is to identify sequence ... more details
The Music Genome Project was first conceived by Will Glaser and Tim Westergren in late 1999. In January 2000, they joined forces with Jon Kraft to found Pandora Radio Pandora Media to bring their idea to market. ref cite interview url http www.venturevoice.com 2009 03 vv show 54 tim westergren of p.html first Tim last Westergren subjectlink Tim Westergren date March 9, 2009 title VV Show 54 Tim Westergren of Pandora accessdate 2011 06 26 interviewer Greg Galant program Venture Voice ref The Music Genome Project was an effort to capture the essence of music at the fundamental level using list of Music Genome Project attributes almost 400 attributes to describe songs and a complex mathematical ... of the Music Genome Project, made up of 5 Genomes Pop Rock, Hip Hop Electronica, Jazz, World ... Music Genome Project is a registered trademark in the United States. The mark is owned by Pandora Media, Inc. ref http tess2.uspto.gov bin showfield?f doc&state e3mah4.2.1 Music Genome Project US Trademark No. 2731047 United States Patent Office ref The Music Genome Project is covered by United ... Music Genome Project US Patent No. 7,003,515 ref This patent shows William T. Glaser, Timothy B. Westergren ... Genome Project attributes Moodbar MusicBrainz Pandora Radio WhoSampled References reflist Further reading refbegin Citation last Castelluccio first Michael title The Music Genome Project journal Strategic ... John first Joyce title Pandora and the Music Genome Project journal Scientific Computing volume 23 issue ... and the music genome project.aspx?terms music 20genome issn 1930 5753 accessdate 2008 08 03 http www.nytimes.com ... 14, 2009 refend External links http www.pandora.com mgp.shtml The Music Genome Project short historical ... westergren the story behind pandora Interview with Tim Westergren about the Music Genome Project ... by Jean claude Perez 1994 SACEM GEN0694 Category Online music and lyrics databases hr Music Genome Project it Music Genome Project he lt Muzikos genomo projektas pl Music Genome ... more details
Unreferenced date November 2008 COI date November 2008 The GDB Human Genome Database was a community curated collection of human genomic data. What set GDB apart from other biological databases was its use of world class leaders in human genetics to act as curators for the data. In order to ensure a high degree of quality, records within GDB were subjected to a process of peer review , not unlike a traditional publication. Due to the International collaboration which made up the human genome project, GDB received funding from numerous sources in both Europe and Asia. History In 1989 the Howard Hughes Medical Institute provided funding to establish a central repository for human genetic map ping data. This project ultimately resulted in the creation of the GDB Human Genome DataBase in 1990. It was a key database in the Human Genome Project . Established under the leadership of Dr. s Peter L. Pearson Peter Pearson and Dick Lucier, GDB received significant financial support from the US Department of Energy and the National Institutes of Health . Located at the Johns Hopkins University School of Medicine , GDB became a source of high quality mapping data which were made available both on line as well as through numerous printed publications. In 1998, the change of focus in the human genome project redirected funds which were previously available for GDB. However that same year, Dr. A. Jamie Cuticchia obtained funding from Canadian public and private sources to continue the operations of GDB. While the data curation continued to be performed at Johns Hopkins, GDB central operations were moved to The Hospital for Sick Children in Toronto, Ontario, Canada. In 2003 RTI International became the new host for GDB where it continued to be maintained as a public resource for high quality genetic and genomic information. On June 1, 2008 RTI International shut down GDB operations. External links DEFAULTSORT Gdb Human Genome Database Category Biological databases Biological database ... more details
Bacterial genomes are generally smaller and less variant in size between species when compared with genome ... between the number of genes and the genome size of bacteria, suggesting that bacteria have relatively ... species have undergone genomic degradation resulting in a decrease in genome size from their ancestral ... the general trend of bacterial genome decay and the relatively small size of bacterial genomes. Compelling ... bias. Bacterial genomes Unlike eukaryote s, bacteria show a strong correlation between genome size and number of functional genes in a genome. ref D. R. Gregory TR, The Evolution of the Genome. San ... and the size of a genome is the presence of non coding or junk DNA . As such, it is clear that bacteria ... in genome size when compared with the genome sizes of other major groups of life. ref name GregorySynergy Genome size is of little relevance when considering the number of functional genes in eukaryotic species. In bacteria however, the strong correlation between the number of genes and the genome ... an integral role in their respective genome sizes. Free living bacteria have the largest genomes out ... acquired pathogen icity. Facultative and recently evolved pathogenic bacteria exhibit a smaller genome ... of bacteria and genome size raises questions as to the mechanisms of bacterial genome evolution. Researchers have developed several theories to explain the patterns of genome size evolution amongst bacteria. Theories of bacterial genome evolution Doubling time One theory predicts that bacteria have smaller genomes due to a selective pressure on genome size to ensure faster replication. The theory ... by Mira et. al. indicated little to no correlation between genome size and doubling time . ref name ... there is some selective pressure on bacteria to maintain small genome size . Deletional bias Selection ... can be used to explain the genome sizes of various types of bacteria. A study done by Mira et. al. examined ... bias is present in the respective genome sizes of free living bacteria, facultative and recently ... more details
Image EBI and Sanger Center, Genome campus, Cambridgeshire.jpg thumb European Bioinformatics Institute EBI and part of the Sanger Institute on the Genome Campus The Wellcome Trust Genome Campus is a scientific research campus built in the grounds of Hinxton Hall, located in the village of Hinxton , Cambridgeshire . It is owned by the Wellcome Trust , and its largest component is the Wellcome Trust Sanger Institute which employs around 900 people. It also is the site of the European Bioinformatics Institute EBI , the bioinformatics outstation of the European Molecular Biology Laboratory , which currently employs around 400 people. File hinxton hall.jpg thumb The site hosted the Medical Research Council UK MRC Rosalind Franklin Center for Genomics Research until its closure in 2005 . In addition to the research institutions, there are facilities on the campus dedicated to training and conferences these include the former Hinxton Hall buildings. coord 52 05 N 0 11 E region GB type city source GNS enwiki display title External links commonscat Genome campus http www.hinxton.wellcome.ac.uk Official Website http images.businessweek.com ss 06 12 1201 id awards source 8.htm BusinessWeek Architectural Record Awards page Wellcome Trust Category Cambridgeshire Category Wellcome Trust UK org stub biosci stub ... more details
Infobox journal title Cytogenetic and Genome Research cover editor M. Schmid discipline Cytogenetics , cell biology , genetics , genomics abbreviation Cytogenet. Genome Res. formernames Cytogenetics, Cytogenetics and Cell Genetics publisher Karger Publishers country frequency 16 year history 1962 present openaccess license impact 1.729 impact year 2009 website http content.karger.com ProdukteDB produkte.asp?Aktion JournalHome&ProduktNr 224037 link1 http content.karger.com ProdukteDB produkte.asp?Aktion BackIssuesJG&ProduktNr 224037 link1 name Online archive link2 link2 name JSTOR OCLC 1787030 LCCN 2002260266 CODEN CGRYAJ ISSN 1424 8581 eISSN 1424 859X Cytogenetic and Genome Research is the name of a Peer review peer reviewed scientific journal that was established in 1962. It was published previously under the names Cytogenetics 1962 1972 and Cytogenetics and Cell Genetics 1973 2001 . Abstracting and indexing The journal is abstracted and indexed in Current Contents , PubMed MEDLINE , and EMBASE EMBASE Excerpta Medica . According to the Journal Citation Reports , the journal has a 2009 impact factor of 1.729. ref name WoS cite web url http isiwebofknowledge.com title Web of Science year 2011 accessdate 2011 05 24 ref References Reflist External links Official website 1 http content.karger.com ProdukteDB produkte.asp?Aktion JournalHome&ProduktNr 224037 DEFAULTSORT Cytogenetic And Genome Research Category Molecular and cellular biology journals Category Genetics journals Category Publications established in 1962 Category Karger academic journals ... more details
Wikify date December 2010 Genome Therapeutics Corp. Collaborative Research Inc. In 1961 Orrie M. Friedman ref cite journal journal Boston Globe date July 1, 2009 title Dr. Orrie M. Friedman, 94, biotech pioneer url http www.boston.com yourtown waltham articles 2009 07 01 dr orrie m friedman 94 biotech pioneer ref founded one of the first biotech companies under the name Collaborative Research Inc. nasdaq CRIC It produced one of the first linkage maps of the whole human genome in the mid 1980s. ref name gtc cite journal title Capitalizing on the genome date May 1996 volume 13 pages 1 url http www.nature.com ng wilma v13n1.867861436.html ref GTC It changed its name to Genome Therapeutics also call GTC, Genomecorp.com, nasdaq GENE and produced in 1994 the first commercial genome sequence, ref name gtc that of Helicobacter pylori, the pathogen responsible for peptic ulcers. The rights to the genome were sold to Astra AB of Sweden for 22 million and a similar deal struck with Schering Plough. ref name gtc In addition to infectious agents, it also worked on heritable diseases including asthma ref cite journal url http www.highbeam.com doc 1P2 8393647.html title Waltham firm lands 67m deal Genome Therapeutics expands asthma venture journal HighBeam Research date December 24, 1996 ref Oscient In 2004 Genome Therapeutics changed its name to Oscient Pharmaceuticals nasdaq OSCIQ ref cite web title Genome Therapeutics Changes Name to Oscient Pharmaceuticals Corporation to Reflect Focus on Drug Development and Commercialization url http investors.oscient.com phoenix.zhtml?c 97238&p irol newsArticle&ID 514137 date April 13, 2004 ref and its sequencing division joined with Agencourt. The latter spun out Agencourt Personal Genomics which was acquired by ABI for 120 million in 2007. ref cite journal journal GenomeWed Daily News url http www.genomeweb.com sequencing abi developing agencourts sequencing technology high priority title For ABI, Developing Agencourt s Sequencing Technology ... more details
infobox biodatabase title The UCSC Genome Browser logo File Database.png description The UCSC Genome ... year 2011 month Jan title The UCSC Genome Browser database update 2011 journal Nucleic Acids Res. volume ... license versioning frequency curation bookmark version The UCSC Genome Browser is an on line genome ... genome browser at UCSC . Genome Res. 2002 Jun 12 6 996 1006. ref ref Kuhn, RM, Karolchik D, Zweig ... Genome Browser Database update 2009 . Nucleic Acids Res. 2009 Jan 37 D755 D761 ref It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate ... of the data at many levels. The Genome Browser Database, browsing tools, downloadable data files, and documentation can all be found on the UCSC Genome Bioinformatics http genome.ucsc.edu website ... Cruz in 2000, the UCSC Genome Browser began as a resource for the distribution of the initial fruits of the Human Genome Project . Funded by the Howard Hughes Medical Institute and the National Human Genome Research Institute, NHGRI one of the US National Institutes of Health , the browser offered a graphical display of the first full chromosome draft assembly of human genome sequence. Today the browser ... Browser has expanded to accommodate genome sequences of all vertebrate species and selected invertebrates ..., or six times more total sequence than the size of the genome. ref now including 46 species. High .... more below on multiple alignment tracks . The species hosted with full featured genome browsers ... Genome Browser presents a diverse collection of annotation datasets known as tracks and presented ... is to show the genome sequence in the horizontal dimension, and show graphical representations ... of the 81 genome assemblies many of the 46 species have more than one assembly , the browser allows ... that distinguishes the UCSC Browser from other genome browsers is the continuously variable nature ... in the genome image and expand it to occupy the full screen. Researchers may also use the browser ... more details
The Personal Genome Project PGP is a long term, large cohort study which aims to sequence and publicize the complete genomes and medical records of 100,000 volunteers, in order to enable research into personalized medicine . It was initiated by Harvard University s George Church and announced in January 2006. ref Emily Singer. http www.technologyreview.com BioTech Therapeutics wtr 16169,259,p1.html The Personal Genome Project , Technology Review , 20 January 2006 ref ref cite news url http www.nytimes.com 2010 06 08 science 08church.html? r 1 title Scientist at Work George M. Church On a Mission to Sequence the Genomes of 100,000 People publisher The New York Times date 2010 06 07 accessdate 2010 08 18 first David last Duncan ref Volunteers are currently accepted only if they are permanent residents of the US, and are able to submit tissue and or genetic samples in the US. The project will publish the genotype the full DNA sequence of all 46 chromosome s of the volunteers, along with extensive information about their phenotype medical records, various measurements, Magnetic resonance imaging MRI images, etc. All data will be placed within the public domain and made available over the Internet ... discrimination by insurers and employers if the genome shows a predisposition for certain diseases ... Angrist, Duke Institute for Genome Sciences and Policy ref Misha Angrist, Robert M. Cook Deegan http www.thenewatlantis.com archive 11 angristcook deegan.htm Who Owns the Genome? The New Atlantis ... 19824 Your Personal Genome , Technology Review , 6 December 2007 ref It s 2011. What s been done since 2007? See also Human Genome Project Personal genomics References Reflist External links http www.personalgenomes.org ... 16 08 ff church Wired How the Personal Genome Project Could Unlock the Mysteries of Life Category Human genome projects Category Cohort studies Category DNA sequencing de Personal Genome Project es Personal Genome Project ... more details
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