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Encyclopedia results for Haemophilia A

Haemophilia A





Encyclopedia results for Haemophilia A

  1. Haemophilia

    as per the usual policy, please leave the British spelling haemophilia as is. Infobox disease Name Haemophilia Image PBB Protein F8 image.jpg Caption Deficiency in coagulation factor VIII factor  VIII is the most common cause of haemophilia. DiseasesDB 5555 DiseasesDB mult DiseasesDB2 5561 DiseasesDB2 ... 306900 OMIM2 264900 MedlinePlus 000537 eMedicineSubj med eMedicineTopic 3528 MeshID D025861 Haemophilia .... Haemophilia A clotting factor VIII deficiency is the most common form of the disorder, present ... 21 work ref Haemophilia B factor IX deficiency occurs in around 1 in about 20,000 34,000 male births. Like most recessive sex linked , X chromosome disorders, haemophilia is more likely to occur in males ... and haemophilia is rare, the chance of a female having two defective copies of the gene is very ... it is not impossible for a female to have haemophilia, it is unusual a female with haemophilia ... sex linked haemophilia C due to coagulant factor XI deficiency, which can affect either sex, is more ... population groups. Haemophilia lowers blood plasma clotting factor levels of the coagulation factors ... 87&parent 278 Key facts what is haemophilia? The Haemophilia Society. ref Patients with more severe haemophilia suffer more severe and more frequent bleeds, while patients with mild haemophilia typically ... and re bleeding are the diagnostic symptoms of haemophilia. Internal bleeding is common in people with severe haemophilia and some individuals with moderate haemophilia. The most characteristic type ... and requires treatment. Children with mild to moderate haemophilia may not have any signs or symptoms ... with mild haemophilia may not have noticeable symptoms for many years. Often, the first sign ... varies with severity and adequate treatment. People with severe haemophilia who don t receive ... treatment was 50 60 years. ref name emed Today with appropriate treatment, males with haemophilia ... of people with severe haemophilia has shifted from bleeding haemorrhage to HIV AIDS acquired through ...   more details



  1. Haemophilia A

    . Mol Pathol 2002 55 1 ref Severity There are numerous different mutations which cause haemophilia ... with haemophilia often have some level of active clotting factor. Individuals with less than 1 active factor are classified as having severe haemophilia, those with 1 5 active factor have moderate haemophilia, and those with mild haemophilia have between 5 40 of normal levels of active clotting ... time PT and bleeding time . PTT test are the first blood test done when haemophilia is indicated. However ... has been made available to determine an individual s risk of attaining or passing on haemophilia. Diagnosis of haemophilia A also includes a severity level which can range from mild to severe based on the amount ... change throughout an individual s life. Severe haemophilia A is the most common form occurring in 60 of patients. Severe haemophilia A is indicated by active Factor VIII levels less than 1 or 2 ... spontaneously without trauma or injury. Moderate haemophilia is indicated by active Factor VIII levels ... bleeds. Mild haemophilia is indicated by active Factor VIII levels between 5 25 . Patients with mild haemophilia often experience few or no bleeding episodes except in the case of serious Physical trauma ... The two most common differential diagnosis differential diagnoses are haemophilia B also known as Christmas ... in von Willebrand factor needed for the proper functioning of Factor VIII. Haemophilia C is also a possible ... for haemorrhage in patients with haemophilia and factor inhibitors See also Haemophilia List of hemophilia organizations List of haemophilia organizations Contaminated haemophilia blood products ... NIH UW entry on Hemophilia A Hematology X linked disorders Category Haemophilia Category Defects ...   more details



  1. Haemophilia C

    Infobox disease Name Haemophilia C Image Caption DiseasesDB 29376 ICD10 ICD10 D 68 1 d 65 ICD9 ICD9 286.2 ICDO OMIM 264900 MedlinePlus eMedicineSubj ped eMedicineTopic 964 eMedicine mult eMedicine2 med 3515 MeshID D005173 Haemophilia C is a mild form of haemophilia affecting both sexes. However, it predominantly occurs in Jews of Ashkenazi descent. It is the fourth most common coagulation disorder after von Willebrand s disease and haemophilia Haemophilia A A and Haemophilia B B . ref http www.gpnotebook.co.uk cache 885719013.htm ref In the USA it is thought to affect 1 in 100,000 of the adult population, making it 10 as common as haemophilia A. ref name eMed http www.emedicine.com ped topic964.htm eMedicine Hemophilia C Article by Prasad Mathew, MBBS, DCH Bot generated title ref It is caused by a deficiency of coagulation factor XI and is distinguished from haemophilia A and B by the fact it does not lead to bleeding into the joints. Furthermore, it has autosomal inheritance, since the gene for factor XI is located on chromosome 4 close to the prekallikrein gene and it is not completely dominance genetics recessive , individuals who are heterozygous also show increased bleeding. ref name eMed Many mutations exist, and the bleeding risk is not always influenced by the severity of the deficiency. Treatment is usually not necessary, except in relation to Surgery operation s, leading to many of those having the condition not being aware of it. In these cases, fresh frozen plasma or recombinant factor XI may be used, but only if necessary. The afflicted may often suffer nosebleeds ... id 91&parent 278 Key facts other bleeding disorders Bot generated title ref Haemophilia C was first discovered in a young Ashkenazic Jewish American in the 1950s. Symptoms The symptoms of Haemophilia C are the same as those for other forms of haemophilia, mainly ref http www.doctorndtv.com topics .... Heavy menstrual bleeding in females. References reflist Hematology Category Haemophilia Genetic ...   more details



  1. Haemophilia B

    Infobox disease Name Haemophilia B ICD10 ICD10 D 67 d 65 ICD9 ICD9 286.1 ICDO Image Caption OMIM 306900 MedlinePlus 000539 eMedicineSubj emerg eMedicineTopic 240 DiseasesDB 5561 MeshID D002836 Haemophilia B or hemophilia B is a coagulation blood clotting disorder caused by a mutation of the Factor IX gene , leading to a deficiency of Factor IX. It is the second most common form of haemophilia , rarer than haemophilia A . It is sometimes called Christmas disease after Stephen Christmas , the first patient described with this disease. ref WhoNamedIt synd 2321 Christmas disease ref In addition, the first report of its identification was published in the Christmas edition of the British Medical Journal . ref cite journal author Biggs R, Douglas AS, MacFarlane RG, Dacie JV, Pitney WR, Merskey C, O Brien JR title Christmas disease a condition previously mistaken for haemophilia journal Br Med J volume 2 issue 4799 pages 1378 82 year 1952 pmid 12997790 doi pmc 2022306 ref Treatment Treatment bleeding prophylaxis is by intravenous infusion of factor IX. Factor IX has a longer half life than factor VIII Deficient in Haemophilia A and as such factor IX can be transfused less frequently. Genetics The factor IX gene is located on the X chromosome Xq27.1 q27.2 . It is an X linked recessive trait, which explains why, as in haemophilia A, only males are usually affected. 1 in 50,000 males are affected. Pathophysiology Factor IX deficiency leads to an increased propensity for haemorrhage . This is in response to mild trauma or even spontaneously, such as in joints hemarthrosis haemarthrosis or muscles. European royal families A study published in 2009 identified the blood disease affecting the royal families of Great Britain, Germany, Russia and Spain as haemophilia B on the basis of genetic ... See also Haemophilia C Haemophilia in European royalty References references External links http www.ncbi.nlm.nih.gov ... Haemophilia es Hemofilia B pl Choroba Christmasa pt Hemofilia B ru B ...   more details



  1. Haemophilia in European royalty

    Haemophilia figured prominently in the history of European royalty in the 19th and 20th centuries. Britain ... the disease. For this reason, haemophilia was once popularly called the royal disease . Tests of the remains of the Romanov imperial family show that the specific form of haemophilia passed down by Queen Victoria was likely the relatively rare Haemophilia B . ref name sciencenow http news.sciencemag.org ... diseases in humans recessive , males only inherit one X chromosome, from their mothers. Thus if the haemophilia gene is transmitted on it, there is no possibility for the male to inherit a haemophilia ... for haemophilia on one of her X chromosomes will also have inherited a second X chromosome from the other parent which is likely to carry a haemophilia free gene that would prevent full expression of symptoms. Females who inherit the gene for Haemophilia A or B from both parents would be expected ... . Although an individual s haemophilia can usually be traced in the ancestry, in about 30 of cases ... of the disease in modern cases of haemophilia among royalty. Queen Victoria s father, Prince Edward ... of her mother having had a lover who suffered from haemophilia is minuscule given ... daughter, Victoria, Princess Royal Victoria , apparently escaped the haemophilia gene as it did not appear ... Arthur were not haemophiliacs. However, her son Leopold was a sufferer of haemophilia and her daughters Alice and Beatrice were confirmed carrier s of the gene. Queen Victoria family tree British haemophilia ... not had haemophilia . Princess Irene of Hesse and by Rhine later Princess Heinrich of Prussia , passed ... son of the future Edward VII of the United Kingdom King Edward VII had she accepted, haemophilia ... and all four of his sisters. Alexei s haemophilia was one of the factors contributing to the collapse ... or to transmit haemophilia. Princess Beatrice Princess Beatrice, Princess Henry of Battenberg Princess ... haemophilia. Prince Leopold of Battenberg later, Lord Leopold Mountbatten . Died at age 32 during ...   more details



  1. Contaminated haemophilia blood products

    Contaminated haemophilia blood products were a serious public health problem in the late 1970s through 1985. These products caused large numbers of haemophilia cs to become infected with HIV and hepatitis C . The companies involved included Alpha Therapeutic Corporation , Rhone Poulenc Rorer Inc., a unit of Rhone Poulenc S.A., Bayer Corporation and its Cutter Laboratories Cutter Biological division, Baxter International and its Hyland Pharmaceutical division . ref name NYTimes1996 cite news title Blood, Money and AIDS Hemophiliacs Are Split Liability Cases Bogged Down in Disputes url http www.nytimes.com 1996 06 11 business blood money aids hemophiliacs are split liability cases bogged down disputes.html?pagewanted print first Barry last Meier date 1996 06 11 work The New York Times accessdate 2012 04 09 ref Estimates range from 6,000 to 10,000 haemophiliacs in the United States becoming infected with HIV. ref name NYTimes1996 ref name SFChron cite news url http ww2.aegis.com news sc 2003 SC030603.html title Bad blood between hemophiliacs, Bayer Patients sue over tainted transfusions spreading HIV, hep C work San Francisco Chronicle first Jim Herron last Zamora date 2003 06 03 accessdate 2006 09 20 ref It is believed that these companies recruited and paid donors from high risk populations including former prisoners, homosexual men, injection drug users, and plasmapheresis facilities in prisons e.g. Arkansas Prison Plasma Scandal and in cities already having large numbers of these persons to obtain blood plasma used for the production of Factor VIII and Factor IX . These companies allegedly failed to follow United States federal law mandates to exclude donors with a history ... children, suffering from haemophilia and the blood disease thalassemia thalassaemia . ref name ... , Rh ne Poulenc and Alpha Therapeutic met with leaders of the haemophilia community to outline ... Haemophilia Blood Products Category HIV AIDS Category Haemophilia da Bl dersagen de Infektionen ...   more details



  1. Stephen Christmas

    Stephen Christmas 12 February 1947 20 December 1993 was the first patient described to have Christmas disease or Haemophilia B in 1952 by a group of British doctors. Biography Stephen was born to a United Kingdom British family in London . He emigrated to Toronto , Canada with his family, and was there at the age of 2 years that haemophilia was diagnosed at the Hospital for Sick Children . The family returned to London in 1952 to visit their relatives, and during the trip Stephen was admitted to hospital. A sample of his blood was sent to the Oxford Haemophilia Centre in Oxford , where Rosemary Biggs and R.G. McFarlane discovered that he was not deficient in Factor VIII , which is normally decreased in classic haemophilia, but a different protein, which received the name Christmas factor in his honour and later Factor IX . Stephen enrolled in the Ryerson Institute of Technology now Ryerson University in Toronto studying photography . He worked as a taxicab driver after graduation and was employed for some years as a medical photographer at the Hospital for Sick Children in Toronto. Stephen was dependent on blood transfusion blood and plasma transfusions , and was infected with HIV in the period during which blood was not routinely screened for this virus. He became an active worker for the Canadian Haemophilia Society and campaigned for transfusion safety ever since getting infected, but developed AIDS , of which he died in 1993. References Giangrande PL. Six characters in search of an author the history of the nomenclature of coagulation factors . Br J Haematol 2003 121 703 12. DOI 10.1046 j.1365 2141.2003.04333.x PMID 12780784. Biggs RA, Douglas AS, MacFarlane RG, Dacie JV, Pittney WR, Merskey C, O Brien JR. Christmas disease a condition previously mistaken for haemophilia. British Medical Journal Br Med J 1952 2 1378 1382. PMID 12997790. Persondata Metadata see Wikipedia Persondata . NAME Christmas, Stephen ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 12 Feb ...   more details



  1. List of hemophilia organizations

    Note that haemophilia is a UK spelling difference, so as per the usual policy please leave the spelling as is. This is a list of hemophilia organizations , it includes the numerous organizations around the world which are formed for the support of people with hemophilia , including advocacy and education groups. ref http www.wfh.org 2 8 8 5 Link1 Nat 27lHemoSites.htm List of National Hemophilia Sites World Federation of Hemophilia ref Hemophilia or Haemophilia is a group of heredity hereditary genetic disorder s that impair the body s ability to control blood clotting or coagulation , which is used to stop bleeding when a blood vessel is broken. National and international advocacy and support organizations File World federation of hemophilia.png right thumb 200px The World Federation of Hemophilia is the largest hemophilia organization in the world, with member organizations in 113 countries ... of Haemophilia Associations http www.hemoex.it Association of Haemophiliacs and Thalassaemics ... Association of Haemophiliacs of Piemonte http www.aiceonline.it Association of Italian Haemophilia Centres http www.haemophilia.org.uk UK Haemophilia Society charity http www.haemophilia.ie Irish Haemophilia Society http www.ehc.eu European Haemophilia Consortium EHC http www.hemofilic.ro Romanian ... Haemophilia Society http www.turkhemoder.org Turkish Haemophilia Society http www.egehemoder.org ... Aleh http www.haemogroups.info Haemo Groups Connecting People With haemophilia And Other Bleeding Disorders African http www.haemophilia.org.za South African Haemophilia Foundation Asian http www.hemophilia.in ... Hemophilia Society of Singapore Pacific http www.haemophilia.org.au Haemophilia Foundation Australia HFA http www.haemophilia.org.nz Haemophilia Foundation of New Zealand Inc. http www.hemofilia.or.id ... 1&SRETRY 0 Haemophilia the official journal of the World Federation of Hemophilia published by John Wiley & Sons . References Reflist Category Lists of organizations Hemophilia Category Haemophilia ...   more details



  1. Ted Tuddenham

    Orphan date February 2009 Professor Edward G. D. Tuddenham is one of the world s leading haematology haematologists Citation needed date August 2009 and until 2005 was head of the Medical Research Council Haemostasis and Thrombosis Research Group at Imperial College , London . Professor Tuddenham is a pioneer in the field on haemophilia and was responsible for the cloning of the factor VIII gene, which led to the highly effective and safe treatments available to haemophilia sufferers today. In more recent years, he has been actively involved in several gene therapy for haemophilia pre clinical studies. He is currently Professor of Haemophilia at University College London and Director of the Haemophilia Centre at the Royal Free Hospital. References cite web url http www.asth.org.au downloads Barry Firkin Orator Professor Ted Tuddenham.pdf title 2006 Barry Firkin Orator Professor Ted Tuddenham The FVXIII Story author Mark Smith cite journal title In search of the eighth factor a personal reminiscence author E. G. D. Tuddenham journal Journal of Thrombosis and Haemostasis date March 2003 volume 1 issue 3 pages 403 409 doi 10.1046 j.1538 7836.2003.00163.x url http www.blackwell synergy.com doi full 10.1046 j.1538 7836.2003.00163.x pmid 12871437 Persondata Metadata see Wikipedia Persondata . NAME Tuddenham, Ted ALTERNATIVE NAMES Edward G. D. Tuddenham SHORT DESCRIPTION Ted DATE OF BIRTH PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Tuddenham, Ted Category Hematologists Category Living people ...   more details



  1. Christine Lee

    Christine Lee is an English medical researcher. She is Emeritus Professor of Haemophilia in the University of London , ref cite news url http news.bbc.co.uk 2 hi health 6563669.stm work BBC News title Contaminated blood inquiry begins date 2007 04 18 accessdate 2010 04 30 ref and founding Editor of Haemophilia journal Haemophilia . Citation needed date February 2010 She trained in medicine at the University of Oxford, where she was awarded First Class Honours and was the first female scholar of the University of Oxford Medical School. She was awarded a Doctorate of Science Medicine by the University of London in 1996. Citation needed date February 2010 Notes references External links http www.blackwellpublishing.com journal.asp?ref 1351 8216 Persondata Metadata see Wikipedia Persondata . NAME Lee, Christine ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Lee, Christine Category Living people Category Year of birth missing living people Category English academics Category Medical researchers Category Alumni of the University of London Category Alumni of the University of Oxford Category Alumni of St George s, University of London Category Academics of the University of London England academic bio stub ...   more details



  1. Tainted blood scandal (United Kingdom)

    COI date February 2010 Contaminated blood was given to many thousands of people in the United Kingdom during the 1970s and 1980s. The Independent Inquiry into Contaminated Blood and Blood Products, chaired by Peter Archer, Baron Archer of Sandwell Baron Archer of Sandwell , aimed to uncover the causes of the events that led to thousands of infections and deaths. ref cite web url http www.independent.co.uk life style health and families health news delays led to thousands receiving contaminated blood 1629555.html title Delays Led to Thousands Receiving Contaminated Blood author Sam Marsden publisher The Independent date 23 February 2009 accessdate 2010 02 14 ref Lord Robert Winston described it as the worst treatment disaster in the history of the National Health Service ref Cite web url http www.channel4.com news articles society health haemophilia grant protest at lords 2493022 title Haemophilia grant protest at Lords author PA News publisher Channel 4 date 2008 10 09 ref . See also Contaminated haemophilia blood products References Reflist External links http www.archercbbp.com The Archer Independent Public Inquiry http wwww.taintedblood.info Help Group for those affected and infected by Contaminated Blood & Blood Products http www.haemophilia.org.uk The UK Haemophilia Society http www.youtube.com CampaignTB Video, News and Documentary Archive http www.manorhousegroup.co.uk A group for those infected with Hepatitis C, through Contaminated Blood and Blood Products DEFAULTSORT Tainted Blood Scandal United Kingdom Category Medical scandals in the United Kingdom Category HIV AIDS in the United Kingdom ...   more details



  1. Lindsay Tribunal

    The Lindsay Tribunal was set up in Ireland in 1999 to investigate the infection of haemophiliacs with HIV and Hepatitis C from contaminated blood products supplied by the Blood Transfusion Service Board . There are about 400 haemophiliacs in Ireland. According to the tribunal a minimal figure of 250 haemophilliacs were infected with HIV or Hepatitis C while receiving treatment from the BTSB before 1985. Haemophilia is a genetic condition where the blood does not clot as quickly as normal due to a deficiency in certain proteins. This means they can suffer from internal bleeding bruises and sprains can be much more serious for haemophiliacs. Haemophiliacs may be treated by transfusions of the protein they are deficient in. One source of this protein is from human blood. Heat treatment of blood products was started in the mid eighties. Heat treatment of blood products reduces the probability of infection from them. Since 1992 recombinant proteins are generally used, which contain little, if any, human blood products and thus have a negligible risk of contamination. Most of the blood products used by the BTSB were from local donations. However, some of it came from American suppliers which included blood from prisoners and drug addicts, who had a high risk of infection. Findings The Tribunal criticised the National Haemophilia Centre for its slow response to the risk of HIV infection. Findings of the Tribunal included Patients were routinely started on home treatment with possibly dangerous commercial blood products, after the risk of infection had been discovered. Unheated blood products were probably not recalled after the safer heat treated products became available. There was no formal means for communicating with regional centres to stop using unheated blood products. There was an unacceptable delay between testing for HIV and Hepatitis and notification of the results up to 4 years Links http www.haemophilia society.ie Irish Haemophilia Society Website http 209.85. ...   more details



  1. Tainted blood scandal

    The terms tainted blood scandal , contaminated blood scandal , or infected blood scandal may be a reference to Contaminated haemophilia blood products Factor 8 The Arkansas Prison Blood Scandal , the investigative documentary by Kelly Duda that exposes the tainted blood sales from Arkansas prisons. Health Management Associates Arkansas company HMA scandal Health Management Associates scandal , the Canadian tainted blood scandal that began in 1986. Royal Commission of Inquiry on the Blood System in Canada HIV tainted blood scandal Japan , or Infected blood scandal France Tainted blood scandal United Kingdom disambig ...   more details



  1. Pharmacological gene therapy

    Unreferenced stub auto yes date December 2009 Orphan date December 2009 Pharmacological gene therapy is a new field that combines pharmacology pharmacological therapy and gene therapy . It is used either to prevent a defective gene from producing its protein or to increase the concentration of normal protein produced in the body by insertion of DNA or RNA fragments. It can also be using to generate immunity from contagious disease, such as TB, via the process of DNA vaccination. Gene Therapeutics can be used to treat such conditions as Cystic Fibrosis via the addition of a normal CFTR gene , Haemophilia A or even some of the complications of AIDS . It uses a number of methods including Gene augmentation Targeted Inhibition using Antisense or antigene technology Cell Killing either direct or assisted and DNA vaccination . DEFAULTSORT Pharmacological Gene Therapy Category Pharmacology Pharma stub ...   more details



  1. Ortner's syndrome

    Image gray505.png right 220px thumb Image of aortic anatomy showing proximity of vagus nerve and its recurrent laryngeal nerve recurrent branch to the aorta Ortner s syndrome is a rare cardiovocal syndrome and refers to recurrent laryngeal nerve palsy from cardiovascular disease . ref cite journal author Bickle IC, Kelly BE, Brooker DS title Ortner s syndrome a radiological diagnosis journal Ulster Med J volume 71 issue 1 pages 55 6 year 2002 month May pmid 12137166 pmc 2475354 ref It was first described by N. Ortner, an Austria n physician, in 1897. The most common historical cause is a dilated left atrium due to mitral stenosis , but other causes, including pulmonary hypertension , ref cite journal author Hermans C, Manocha S, McLaughlin JE, Lipman M, Lee CA title Ortner syndrome and haemophilia journal Haemophilia volume 11 issue 5 pages 548 51 year 2005 month September pmid 16128901 doi 10.1111 j.1365 2516.2005.01140.x url http www3.interscience.wiley.com resolve openurl?genre article&sid nlm pubmed&issn 1351 8216&date 2005&volume 11&issue 5&spage 548 ref thoracic aorta aortic aneurysms and aberrant subclavian artery syndrome have been reported. ref cite journal author Escribano JF, Carn s J, Crespo MA, Ant n RF title Ortner s syndrome and endoluminal treatment of a thoracic aortic aneurysm a case report journal Vasc Endovascular Surg volume 40 issue 1 pages 75 8 year 2006 pmid 16456610 url http ves.sagepub.com cgi pmidlookup?view long&pmid 16456610 ref Dysphagia caused by a similar mechanism is referred to as dysphagia aortica , or, in the case of subclavian artery aberrancy, as dysphagia lusoria . Due to compression of recurrent larngeal nerve it can cause the hoarseness of the voice which is also one of the sign of the mitral stenosis. A second Ortner s syndrome, Ortner s syndrome II, refers to abdominal angina . References reflist Category Cardiovascular diseases Category Neurological disorders med stub it Sindrome di Ortner ...   more details



  1. Bad Blood: A Cautionary Tale

    orphan date April 2011 primarysources date April 2011 Infobox film name Bad Blood A Cautionary Tale image Bad Blood A Cautionary Tale.jpg alt director Marilyn Ness producer Marilyn Ness writer Marilyn Ness br Sheila Curran Bernard starring music Joel Goodman br David Bramfitt cinematography David Ford editing Marion Sears Hunter studio distributor released Film date 2010 6 28 runtime country Film US language English budget 300,000 gross Bad Blood A Cautionary Tale is a documentary film about contaminated haemophilia blood products contaminated hemophilia blood products . The film was co written by Marilyn Ness and Sheila Curran Bernard, produced and directed by Marilyn Ness, with cinematography by David Ford, editing by Marion Sears Hunter, and original music score by Joel Goodman and David Bramfitt. The film premiered on July 28, 2010 in New York City . ref cite web url http badblooddocumentary.com screenings title Screenings work badblooddocumentary.com accessdate February 1, 2011 ref References Reflist External links Official website http www.badblooddocumentary.com IMDb title 1773294 Bad Blood A Cautionary Tale Category 2010 films Category American films Category Haemophilia Category English language films Category American documentary films Category 2010s documentary films Category Documentary films about health care Category Documentary films about HIV AIDS documentary film stub ...   more details



  1. Hematospermia

    Infobox disease Name Hematospermia Image Hematospermia.jpg Caption Illustration of hematospermia. DiseasesDB 31879 ICD10 ICD10 R 36 1 r 30 ICD9 ICD9 608.82 ICDO OMIM MedlinePlus eMedicineSubj med eMedicineTopic 3466 MeshID D051516 Hematospermia haematospermia , or Hemospermia, haemospermia or the presence of blood in semen , is most often a benign and idiopathic symptom, but can sometimes result from medical problems such as a urethral stricture , infection of the prostate , or a congenital Haemophilia bleeding disorder , and can occur transiently after surgical procedures such as a prostate biopsy . It is present in less than 2 of urology referrals, although prevalence in the overall population is unknown. Patients with hematospermia should be evaluated by a urologist to identify or rule out medical causes. Idiopathic hematospermia is sometimes treated with tetracycline and prostatic massage . Male diseases of the pelvis and genitals Category Male genital disorders ca Hemosp rmia es Hemospermia fr H mospermie it Emospermia he nl Hemospermie ja pl Hematospermia pt Hemospermia fi Hematospermia ...   more details



  1. Aafact

    Unreferenced stub date December 2009 Orphan date December 2009 Aafact is a monoclonal purified factor VIII concentrate. It consists of a protein fraction prepared from fresh frozen human plasma . It is used in cases of acute haemorrhage, pre operative and post operative treatment and prophylaxis in haemophilia A patients congenital factor VIII deficiency and in patients with an acquired reduction in factor VIII activity. It is available as a powder for infusion for intravenous administration. This transfer of a Blood plasma plasma byproduct into the blood stream of a hemophiliac often led to the transmission of diseases such as HIV and hepatitis before purification methods were improved. In the early 1990s, pharmaceutical companies began to produce Recombinant DNA recombinant synthesized factor products, which now prevent nearly all forms of disease transmission during replacement therapy. See also factor VIII Category Drugs blood drug stub ...   more details



  1. Hemoscrotum

    Orphan date July 2011 Image Hemoscrotum.JPEG thumb A massive hemoscrotum scrotal hematoma which occurred as a Complication medicine complication of inguinal hernia inguinal Hernia repair herniorrhaphy . The scrotum was explored surgically, and a drain surgery drain was left behind seen on the patient s right thigh . A Foley catheter is in place to prevent urinary retention . Hemoscrotum or haemoscrotum in British English is a condition in which blood accumulates inside the scrotum . Hemoscrotum can follow Trauma medicine trauma such as a straddle injury or can be a complication of surgery. It cais often accompanied by testicular pain . It has been reported in patients with Haemophilia hemophilia and following arterial catheter catheterization of the femoral artery . If the diagnosis is not clinically evident, Transillumination Medicine transillumination with a penlight against the scrotum will show a non translucent fluid inside the scrotum. Medical ultrasonography Ultrasound imaging may also be useful in confirming the diagnosis. In severe or non resolving cases, surgical incision and drainage may be required. To prevent recurrence following surgical drainage, a drain surgery drain may be left at the surgical site. Category Male genital disorders disease stub ...   more details



  1. Factor 8: The Arkansas Prison Blood Scandal

    also Contaminated haemophilia blood products References http www.factor8movie.com Factor 8 website ...   more details



  1. HIV-tainted blood scandal (Japan)

    of whom suffered from haemophilia . ref http www.nancho.net anthcult castrhiv.html Miyamoto, Masao ..., affecting a haemophilia patient who was prescribed blood products by his doctor. A second patient ... in the early 1980s and these patients were haemophilia patients or had homosexual experiences. After ... in which individuals were diagnosed with haemophilia for the first time between 1985 and 1986, began ... the 1980s see ama kudari . See also Ryuhei Kawada Contaminated haemophilia blood products Infected ...   more details



  1. Thomas Addis

    articles journal 33 2 9 thomas addis.pdf Thomas Addis 1881 1949 , Scottish Pioneer in Haemophilia Research , a 2003 article about Addis s early studies on haemophilia in The Journal of the Royal ...   more details



  1. Bleeding Hearts

    infobox Book See Wikipedia WikiProject Novels or Wikipedia WikiProject Books name Bleeding Hearts orig title translator image Image JackHarveyBleedingHearts.jpg 175px author Ian Rankin writing as Jack Harvey cover artist country Scotland language English series genre Thriller genre Thriller novel publisher Orion Books release date 1994 media type Print Hardcover Hardback & Paperback pages 416 pages isbn ISBN 0 7528 4332 X oclc 46600414 preceded by Witch Hunt novel Witch Hunt followed by Blood Hunt This article is about the novel. For the plant known as Bleeding Hearts, see Dicentra spectabilis . Bleeding Hearts is a 1994 crime novel by Ian Rankin , under the pseudonym Jack Harvey . It is the second novel he wrote under this name. Plot summary Michael Weston is a professional assassination assassin , but he also suffers from haemophilia . The wealthy father of a girl he killed by mistake years ago has sworn vengeance on the killer, hiring a private detective Hoffer to track him down. Rankin has said that he wrote this book under the influence of Martin Amis novel Money novel Money and that Weston was influenced by that novel s protagonist John Self. Ian Rankin Category 1994 novels Category Thriller novels Category Novels by Ian Rankin Category Works published under a pseudonym thriller novel stub ...   more details



  1. Synovectomy

    Interventions infobox Name PAGENAME Image Caption ICD10 ICD9 ICD9proc 80.7 MeshID OPS301 OtherCodes HCPCSlevel2 Synovectomy is the surgical removal of a part of the synovial membrane of a synovial joint . Indications It is one of the treatment options for certain diseases involving the synovium like Severe rheumatoid arthritis or juvenile idiopathic arthritis Hemarthrosis Synovial osteochondromatosis Synovial chondromatosis Pigmented villonodular synovitis Variants Chemosynovectomy can be performed with osmic acid . ref name Ray2008 cite book last Ray first Charles E. title Pain Management in Interventional Radiology url http books.google.com books?id D5pUkinBbfUC&pg PA178 accessdate 19 July 2011 date 2008 04 21 publisher Cambridge University Press isbn 9780521865920 pages 178 ref Radiosynovectomy has been performed with rhenium 186 and yttrium 90 . ref name Rodriguez MerchanValentino2011 cite book last1 Rodriguez Merchan first1 E. Carlos last2 Valentino first2 Leonard A. title Current and Future Issues in Haemophilia Care url http books.google.com books?id QbboyvWnVIwC&pg PT548 accessdate 19 July 2011 date 2011 04 27 publisher Wiley Blackwell isbn 9781119979388 pages 548 ref References reflist Category Surgical removal procedures Category Orthopedic surgery Surgery stub Bone, cartilage, and joint procedures Ectomy, stomy, and otomy ca Sinovectomia pl Synowektomia ...   more details



  1. Ivar Arosenius

    Image Arosenius self.gif thumb Self portrait by Arosenius. Ivar Axel Henrik Arosenius October 8, 1878 January 2, 1909 from the complications of haemophilia , was a Sweden Swedish Painting painter and author of picture book s. In the latter capacity he is most noted for the book Kattresan The Cat Journey , which was published after his death. He lived in the village of lv ngen , north of Gothenburg . After his death, his house fell into disrepair and was finally demolished. He is buried at stra kyrkog rden, Gothenburg stra kyrkog rden in Gothenburg. In lv ngen, one of the schools, Aroseniusskolan , is named after Ivar Arosenius. Nowadays, some of Ivar Arosenius paintings can be seen at the Museum of Art in Gothenburg. References commonscat http www5.goteborg.se prod kultur konstmuseet dalis2.nsf 535e371e7fd657aec1256a5c0045675f e1caefddb5eded18c1256fe40028ce8c OpenDocument Brief article and self portrait Persondata Metadata see Wikipedia Persondata . NAME Arosenius, Ivar ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH October 8, 1878 PLACE OF BIRTH DATE OF DEATH January 2, 1909 PLACE OF DEATH DEFAULTSORT Arosenius, Ivar Category Swedish painters Category Swedish writers Category 1878 births Category 1909 deaths Sweden writer stub Sweden painter stub es Ivar Arosenius fr Ivar Arosenius hu Ivar Arosenius no Ivar Arosenius nn Ivar Arosenius pt Ivar Arosenius ru , sv Ivar Arosenius ...   more details




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