Infobox Disease Name Hyperglycemia Image Caption DiseasesDB 6234 ICD10 R73.9 ICD9 ICD9 790.29 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D006943 Hyperglycemia or Hyperglyc mia , or high ... mg dl or 7 mmol l is generally held to have hyperglycemia. Chronic levels exceeding 7  Reference ... with a consistent range above 126  mg dl or 7  mmol l is generally held to have hyperglycemia ... Health Institute year 2005 accessdate May 4, 2011 ref Chronic hyperglycemia can be measured via the HbA1c test. The definition of acute hyperglycemia varies by study, with mmol l levels from 8 to 15. ref cite journal author Giugliano D, Marfella R, Coppola L, et al. title Vascular effects of acute hyperglycemia ... during hyperglycemia journal Circulation volume 95 issue 7 pages 1783 90 year 1997 pmid 9107164 ref Signs and symptoms Temporary hyperglycemia is often benign and asymptomatic. Blood glucose levels can .... However, chronic hyperglycemia at levels more than slightly above normal can produce a very wide ... neuropathy may be a result of long term hyperglycemia. In diabetes mellitus by far the most common cause of chronic hyperglycemia , treatment aims at maintaining blood glucose at a level as close to normal as possible, in order to avoid these serious long term complications. Acute hyperglycemia ... or chronic hyperglycemia, with the first three composing the classic hyperglycemic triad Polyphagia ... Acute hyperglycemia alters mood state and impairs cognitive performance in people with type 2 diabetes ... ref Causes The following conditions can also cause hyperglycemia in the absence of diabetes ... diseases frequently overlooked can also cause hyperglycemia. Encephalitis, brain tumors especially ... Hyperglycemia can be a serious problem if not treated in time. In untreated hyperglycemia, a condition ... , nausea and vomiting, and very dry mouth. Chronic hyperglycemia high blood sugar injures the heart ... web title Chronic hyperglycemia may lead to cardiac damage url http www.news medical.net news 20120203 ... more details
Stress hyperglycemia also called stress diabetes or diabetes of injury is a medical term referring to transient elevation of the blood glucose due to the stress medicine stress of illness. It usually resolves spontaneously, but must be distinguished from various forms of diabetes mellitus . It is often discovered when routine blood chemistry measurements in an ill patient reveal an elevated blood glucose. Blood glucose can be assessed either by a bedside fingerstick glucose meter or plasma glucose as performed in a laboratory the latter being more efficacious . A retrospective cohort study by the Mayo Clinic held that bedside glucometry was a reliable estimate of plasma glucose with a mean difference of 7.9  mg dL, but still may not coincide with every individual. ref name Mayo2005 cite journal author Finkielman J, Oyen L, Afessa B title Agreement between bedside blood and plasma glucose measurement in the ICU setting journal Chest volume 127 issue 5 pages 1749 51 year 2005 pmid 15888855 doi 10.1378 chest.127.5.1749 ref The glucose is typically in the range of 140 300  mg dl 7.8 16.7 mM but occasionally can exceed 500  mg dl 28 mM , especially if amplified by drugs or intravenous glucose. The blood glucose usually returns to normal within hours unless predisposing drugs and intravenous glucose are continued. Stress hyperglycemia is especially common in patients with hypertonic dehydration and those with elevated catecholamine levels e.g., after emergency department treatment of acute asthma with epinephrine . Steroid diabetes is a specific and prolonged form of stress hyperglycemia. In some people, stress hyperglycemia may indicate a reduced insulin secretory capacity ... in which significant stress hyperglycemia occurred. Treatment One of the most sweeping changes in intensive ... treatment of stress induced hyperglycemia. ref name survivingsepsis Dellinger RP, Carlet JM, Masur ... well change our approach to the management of stress induced hyperglycemia in the ICU. References ... more details
Glycemia means the presence, or the level, of glucose in one s blood . Related words include Hyperglycemia , an unusually high concentration of sugar in the blood Hypoglycemia , an unusually low concentration of sugar in the blood disambig ... more details
Steroid diabetes also steroid induced diabetes is a medical term referring to prolonged hyperglycemia due to glucocorticoid therapy for another medical condition. It is usually, but not always, a transient condition. Medical conditions The most common glucocorticoids which cause steroid diabetes are prednisolone and dexamethasone given systemically in pharmacologic doses for days or weeks. Typical medical conditions in which steroid diabetes arises during high dose glucocorticoid treatment include severe asthma , organ transplant ation, cystic fibrosis , inflammatory bowel disease , and induction chemotherapy for leukemia or other cancer s. Insulin Glucocorticoids oppose insulin action and stimulate gluconeogenesis , especially in the liver , resulting in a net increase in hepatic glucose output. Most people can produce enough extra insulin to compensate for this effect and maintain normal glucose levels, but those who cannot develop steroid diabetes. Criteria The diagnosis diagnostic criteria for steroid diabetes are those of diabetes mellitus diabetes fasting glucoses persistently above 125  mg dl 7 mM or random levels above 200  mg dl 11 mM occurring in the context of high dose glucocorticoid therapy. Insulin levels are usually detectable, and sometimes elevated, but inadequate to control the glucose. In extreme cases the hyperglycemia may be severe enough to cause nonketotic hyperosmolar coma . Treatment Treatment depends on the severity of the hyperglycemia and the estimated duration of the steroid treatment. Mild hyperglycemia in an immunocompetent patient may not require treatment if the steroids will be discontinued in a week or two. Moderate hyperglycemia ... is the most common treatment. Diagnosis Steroid diabetes must be distinguished from stress hyperglycemia , hyperglycemia due to excessive intravenous glucose, or new onset diabetes of another type. Because ... treatment because subclinical hyperglycemia worsens and becomes symptomatic. Generally, steroid ... more details
Hyperglycinemia refers to a condition where glycine is elevated in the blood. Types include Propionic acidemia , also known as ketotic glycinemia Glycine encephalopathy , also known as non ketotic hyperglycinemia . It may also be a misspelling of hyperglycemia . Short pages monitor This long comment was added to the page to prevent it being listed on Special Shortpages. It and the accompanying monitoring template were generated via Template Longcomment. Please do not remove the monitor template without removing the comment as well. Category Amino acid metabolism disorders medicine stub ... more details
Image clarkeerrorgrid.gif thumb The Clarke Error Grid The Clarke Error Grid Analysis EGA was developed in 1987 to quantify clinical accuracy of patient estimates of their current blood glucose as compared to the blood glucose value obtained in their meter. ref Clarke WL, Cox D, Gonder Frederick LA ,Carter W, Pohl SL Evaluating clinical accuracy of systems for self monitoring of blood glucose. Diabetes Care 10 622 628,1987 ref It was then used to quantify the clinical accuracy of blood glucose estimates generated by meters as compared to a reference value. A description of the EGA appeared in Diabetes Care in 1987. ref http care.diabetesjournals.org cgi content abstract 10 5 622?ijkey 959ce0073ff9f91dfd78630b4259267d96a9db0f&keytype2 tf ipsecsha ref Eventually, the EGA became accepted as one of the gold standards for determining the accuracy of blood glucose meters. The grid breaks down a scatterplot of a reference glucose meter and an evaluated glucose meter into five regions ref http www.fda.gov cdrh oivd guidance 1171.gif ref Region A are those values within 20 of the reference sensor, Region B contains points that are outside of 20 but would not lead to inappropriate treatment, Region C are those points leading to unnecessary treatment, Region D are those points indicating a potentially dangerous failure to detect hypoglycemia or hyperglycemia , and Region E are those points that would confuse treatment of hypoglycemia for hyperglycemia and vice versa. References reflist Category Diabetes de Error Grid Analyse ... more details
unreferenced date August 2010 Van Goethem Syndrome , also called radiodigitofacial dysplasia , is a congenital disorder . Characteristics Very frequent signs of the disorder include Anemia Absence or abnormality of the clavicle Difficulties feeding in infancy High vaulted or narrow palate Narrow, sloping shoulders Downturned mouth Platelet disorders Talipes varus valgus Short stature or dwarfism Hypoplastic thumb Hyperglycemia Diabetes mellitus Absent or abnormal humerus Micrognatia retrognatia Median ray abnormal or cleft hand Restricted joint mobility Causes Empty section date July 2010 Treatments Empty section date July 2010 External links http www.orpha.net consor cgi bin OC Exp.php?Lng DE&Expert 3014 orpha.net Category Rare diseases Category Genetic disorders with no OMIM Category Congenital disorders Category Syndromes Genetic disorder stub ... more details
Unreferenced auto yes date December 2009 Orphan date December 2009 Microcoria is a congenital disease in which the pupil s of the subject are narrower than 2mm in diameter. Microcoria is associated with juvenile onset glaucoma . It is also associated with Pierson syndrome chararacterized by microcoria and congenital nephrotic syndrome. The defect is in the Laminin beta 2 gene on chromosome 3p21 which encodes a protein essential to the glomerular basement membrane. ref Zenker et al., 2004. Zenker M., Aigner T., Wendler O., et al Human laminin beta 2 deficiency causes congenital nephrosis with mesangial sclerosis and distint eye abnormalities. Hum Mol Genet 2004 13 2625 2632 ref It is also part of the known manifestations of a born infant to a mother suffering from uncontrolled hyperglycemia Cn date November 2011 . Other symptoms include transposition of great vessels, respiratory distress secondary to surfactant defect, sacral agensis, jitteriness, irritability, and lethargy due to rebound fetal hypoglycemia. See also Miosis References reflist Category Diseases of the eye and adnexa Eye stub ... more details
Infobox Disease Name MODY 4 Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 606392 MedlinePlus eMedicineSubj eMedicineTopic MeshID MODY 4 is a form of maturity onset diabetes of the young . MODY 4 arises from mutations of the Pdx 1 homeobox gene on chromosome 13 human chromosome 13 . Pdx 1 is a transcription factor vital to the development of the embryonic pancreas. Even in adults it continues to play a role in the regulation and expression of genes for insulin, GLUT2, glucokinase, and somatostatin . MODY 4 is so rare that only a single family has been well studied. A child born with pancreatic agenesis absence of the pancreas was found to be homozygous for Pdx 1 mutations. A number of older relatives who were heterozygous had mild hyperglycemia or diabetes. None were severely insulin deficient and all were controlled with either diet or oral hypoglycemic agent s. References reflist Endocrine pathology Transcription factor coregulator deficiencies endocrine disease stub Category Diabetes ... more details
, from a combination of severe hyperglycemia , dehydration and shock circulatory shock ... is confirmed when the usual blood chemistries in the emergency department reveal hyperglycemia and severe ... illness. Extreme hyperglycemia is accompanied by dehydration due to inadequate fluid intake. Coma ... of obtundation reveals extreme hyperglycemia often above 1800  mg dl 100 mM and dehydration ... more details
insulin delivery can result in hyperglycemia . The appropriate response is to deliver a correction ... to deliver additional insulin in the future to prevent hyperglycemia. Conversely, excessive insulin ... when high waking blood sugars are found, to determine if more insulin is needed to prevent hyperglycemia ... increases in insulin delivery awareness to the signs of hypoglycemia awareness to hyperglycemia ... more details
in the blood hyperglycemia caused by the lack of insulin can lead to further acidity. In healthy ..., hyperglycemia , and dehydration . Particularly in type 1 diabetics the lack of insulin in the bloodstream ... metabolism potentially leading to dangerous glucose and ketone levels in the blood. Hyperglycemia ... more details
, infants display fasting hypoglycemia , postprandial hyperglycemia and hyperinsulinemia , which progress to permanent hyperglycemia and recurrent diabetic ketoacidosis . Pathophysiology Image autorecessive.svg ... leptin may result in improvement of fasting hyperglycemia, hyperinsulinemia, basal glucose, and glucose ... more details
Infobox disease Name Glycogen storage disease type 0 Image Caption DiseasesDB 31944 ICD10 ICD9 ICDO OMIM 240600 OMIM mult OMIM2 611556 MedlinePlus eMedicineSubj ped eMedicineTopic 873 MeshID Glycogen storage disease type 0 is a disease characterized by a deficiency in the glycogen synthase enzyme. Although glycogen synthase deficiency does not result in storage of extra glycogen in the liver, it is often classified with the Glycogen storage disease s because it is another defect of glycogen storage and can cause similar problems. Mutations in the liver isoform , GYS2 , causes fasting hypoglycemia , high blood ketones , increased free fatty acids and low levels of alanine and lactic acid lactate . Conversely, feeding in these patients results in hyperglycemia and hyperlactatemia. There are two versions the muscle version involves GYS1 and the liver version involves GYS2. ref name pmid9691087 cite journal author Orho M, Bosshard NU, Buist NR, et al. title Mutations in the liver glycogen synthase gene in children with hypoglycemia due to glycogen storage disease type 0 journal J. Clin. Invest. volume 102 issue 3 pages 507 15 year 1998 month August pmid 9691087 pmc 508911 doi 10.1172 JCI2890 ref References reflist Inborn errors of carbohydrate metabolism Category Inborn errors of carbohydrate metabolism Category Hepatology endocrine disease stub ... more details
from the leaves of C. spicatus is used to treat diabetes hyperglycemia . However, a 2009 study concluded that this treatment ...had no efficacy in the treatment of obesity induced hyperglycemia. ref ... more details
Injury is damage to a biological organism which can be classified on various bases. Classification By cause Trauma medicine Traumatic injury , a body wound or Shock circulatory shock produced by sudden physical injury, as from violence or accident ref name Dictionary cite encyclopedia title Trauma encyclopedia Dictionary.com year 2010 publisher Dictionary.com, LLC url http dictionary.reference.com browse trauma accessdate 2010 10 31 ref Other injuries from external physical causes, such as Radiation poisoning radiation injury , burn injury or frostbite Injury from infection Injury from toxin or as adverse effect of a pharmaceutical drug Metabolic injury Complications of diabetes due to hyperglycemia Complications of lysosomal storage disease lysosomal and glycogen storage disease s Injury due to autoimmunity Injury due to cancer Injury secondary to any other disease By location Wound , an injury in which skin is torn, cut or punctured an open wound , or where blunt force physical trauma trauma causes a bruise contusion a closed wound . In pathology , it specifically refers to a sharp injury which damages the dermis of the skin. Brain injury Spinal cord injury Nerve injury Soft tissue injury Cell damage , including direct DNA damage By activity Sports injury Occupational injury References reflist Category Injuries ar cs raz fr Blessure ko id Cedera io Vunduro mg Maratra nl Blessure ja simple Injury sk raz te ur zh ... more details
A glucose test is a type of blood test used to determine the amount of glucose in the blood. It is mainly used in Screening medicine screening for any prediabetes or diabetes . ref name medlineplus http www.nlm.nih.gov medlineplus ency article 003438.htm MedlinePlus Blood glucose monitoring Update Date 6 17 2008. Updated by Elizabeth H. Holt, MD, PhD. In turn citing American Diabetes Association. Standards of medical care in diabetes 2008. Diabetes Care. 2008 31 S12 S54. ref In people already having diabetes, blood glucose monitoring is used with frequent intervals in the management of the condition. ref name medlineplus There are several different kinds of glucose tests Fasting blood sugar FBS , fasting plasma glucose FPG 12 hours after eating Postprandial glucose test PC 2 hours after eating Glucose tolerance test continuous testing Random glucose test Reference ranges Fasting blood sugar A range of 4 to 7 mmol l 72 to 126 mg dl before a meal is normal. Continual fasting levels of 5.5 to 7 mmol l 101 125 mg dl causes concern of possible prediabetes and may be worth monitoring. 7 mmol l 126 mg dl and above means a risk of diabetes. After a 12 hour fast, a range of 3.9 to under 5.5 mmol l 70.2 to 100 mg dl is normal a level of 5.6 to under 7 mmol l 100 to 126 mg dl is considered a sign of prediabetes . ref name Medline GTT MedlinePlus 003466 Glucose tolerance test ref Postprandial glucose Main Postprandial glucose test A level of 10 mmol l 180 mg dl 90 minutes after a meal is normal. See also Blood sugar Diabetes Glucose meter Hypoglycemia Hyperglycemia References reflist 2 treatment stub Blood tests Category Blood tests ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 E10.5, E11.5, E12.5, E13.5, E14.5 ICD9 ICD9 250.7 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D003925 Diabetic angiopathy is a form of angiopathy associated with diabetes mellitus . While not exclusive, the two most common forms are Diabetic retinopathy and Diabetic nephropathy , whose pathophysiologies are largely identical. Pathophysiology As insulin is required for glucose uptake, hyperglycemia in diabetes mellitus does not result in a net increase in intracellular glucose in most cells. However, chronic dysregulated blood glucose in diabetes is toxic to cells of the vascular endothelium which passively assimilate glucose. That is, cells in which insulin is not required for intercellular transport of glucose, most notably the pericytes of the microvasculature . In addition to direct glucose induced damage by e.g. glycation , pericytes express enzymes which convert glucose into osmologically active metabolites such as sorbitol leading to hypertonic cell lysis. Over time, pericyte death may result in reduced capillary integrity subsequently, there is leaking of albumin and other proteins into fluid compartments. The glomeruli of the kidneys are especially sensitive see diabetic nephropathy where protein leakage caused by late stage angiopathy results in diagnostic proteinuria and eventually renal failure . In diabetic retinopathy the end result is often blindness due to irreversible retinal damage. Prognosis and complications Diabetes mellitus is the most common cause of adult kidney failure worldwide. It also the most common cause of amputation in the US, usually toes and feet, often as a result of gangrene , and almost always as a result of peripheral vascular disease. Retinal damage from microangiopathy makes it the most common cause of blindness among non elderly adults in the US. Prognosis is generally poor for all forms of Diabetic angiopathy, as symptomatology is tied to the advanceme ... more details
Refimprove date December 2009 Orphan date February 2009 A gainer is a bodybuilding supplement usually composed of both high and low glycemic carbohydrates and protein usually in the form of calcium caseinate, milk and whey protein and often other nutrient s such as certain vitamin s and mineral s. Description and Use Gainers after workout supplements are used by bodybuilding and strength athletes, both amateur and professional alike, as a weight gain supplement or recovery supplement. Gainers are designed especially for use after workout. Pre and post workout supplements are probably the most important supplements to take, after vitamins and minerals. ref http best pre workout supplements.com best post workout supplement ref When performing intensive exercise the stress can cause the release of hormone s such as cortisol in order to quickly make available energy to the body. Cortisol forces Glycogenolysis breakdown of glycogen , protein muscle and fat deposits which are used in gluconeogenesis . Gainers seek to combat this effect after and sometimes during an exercise routine. Most gainers use protein powders whey protein extracts and carbohydrates dextrose, maltodextrine . More advanced gainers add to their recipes ingredients like creatine, l arginine, long chain amino acids, enzymes for better digestion , vitamins, minerals and plant extracts for adaptogen effect. Higher glycemic carbohydrates will prompt a steep rise in blood glucose, forcing an equal release of insulin by the body to counter the long term Hyperglycemia negative effects of high blood sugar , inhibiting the effects of cortisol. Some of the carbohydrates are immediately absorbed by the muscles without insulin. The rest is stored as glycogen in the liver and muscles.The insulin spike, given by carbohydrates, help other supplements ex. creatine , protein to by absorbed better and faster. References Reflist See also http best pre workout supplements.com best post workout supplement post workout suppl ... more details
Citations missing date November 2007 Body fat redistribution BFR syndrome , sometimes called fat derangement , is a medical condition characterized by fat loss or occasionally fat gain , often in the cheeks or face. BFR most often occurs in HIV AIDS patients undergoing antiretroviral therapy. Definition No firm definition of body fat redistribution syndrome exists as yet. At least four syndromes have been described that are characterized by the accumulation of fat, and one by the loss of fat combinations of these may occur in an individual. Gender, age, and pre therapy body weight appear to influence the severity of BFR in patients. BFR is distinct from lipodystrophy , which simply refers to fat loss. Symptoms The most common manifestations of body fat redistribution are accumulations of fat in the central body in the form of a fat pad on the back of the neck and an accumulation of visceral fat in the abdomen or belly. This fat accumulation is accompanied by a loss of subcutaneous fat in the face, arms, legs, and buttocks. Adverse effects Cosmetic concerns may cause patients to refuse or stop treatment. If severe enough, the fat accumulation may result in sleep apnea or other sleep disorders, migraines , decreased range of motion, discomfort due to pressure on internal organs, and general loss of condition. Fat loss may result in pain in the buttocks when seated. Other potential complications resulting from BFR include high cholesterol, high levels of triglycerides , insulin resistance, hyperglycemia , diabetes , gout , and cardiovascular disease . BFR is also associated with certain metabolic abnormalities such as elevations of plasma sugar and fats, but the precise relationship is unknown. Treatment Treatment of symptoms may include cosmetic surgery such as Collagen Medical uses collagen implants treatment of the underlying syndrome may include changing from protease inhibitors to an NNRTI . See also lipodystrophy References http www.sfaf.org treatment beta b39 b3 ... more details
A certified diabetes educator CDE is a health care professional who is specialized and certified to teach people with diabetes how to manage their condition. ref http www.diabetes.org The American Diabetes Association ref ref http centerfordiabetescare.com Center for Diabetes Care ref The CDE is an invaluable asset to those who need to learn the tools and skills necessary to control their blood sugar and avoid Diabetes mellitus Complications long term complications due to hyperglycemia . Unlike an endocrinologist, the CDE can spend as much time with a newly diagnosed person as is needed both for educational purposes and emotional support. Typically the CDE is also a nurse, dietitian, exercise physiologist, pharmacist, or social worker who has further specialized in diabetes education and care management. Formal education and years of practical experience are required, in addition to a formal examination, before a diabetes educator is certified. In the US, certification is awarded by the National Certification Board for Diabetes Educators. ref http www.diabeteseducator.org American Association of Diabetes Educators ref ref http www.ncbde.org National Certification Board for Diabetes Educators ref In Canada, certification is awarded by the http www.cdecb.ca Canadian Diabetes Educator Certification Board. CDECB . In the Philippines, any allied health care professional may apply to be a diabetes educator after taking special courses from the Philippine Association of Diabetes Educators PADE or Association of Diabetes Nurse Educators of the Philippines ADNEP . Qualified graduates of diabetes educator courses can practice as a professional diabetes educator in any Center for Diabetes Care CDC clinic network. The Diabetes Nurse Educator DNE and Certified Lay Educator CLE are the equivalent of CDE certificate in the Philippines. CDEs can work independently for health clinics, medical practices, pharmacies, and for companies that provide diabetes education. References Refere ... more details
Hyperproinsulinemia is a disease where insulin is not sufficiently processed before secretion ref name pmid12829804 cite journal author Dhanvantari S, Shen FS, Adams T, et al. title Disruption of a receptor mediated mechanism for intracellular sorting of proinsulin in familial hyperproinsulinemia journal Mol. Endocrinol. volume 17 issue 9 pages 1856 67 year 2003 month September pmid 12829804 doi 10.1210 me.2002 0380 url http mend.endojournals.org cgi pmidlookup?view long&pmid 12829804 ref and immature forms of insulin make up the majority of circulating insulin immunoreactivity in both fasting and glucose stimulated conditions insulin immunoreactivity refers to all molecules detectable by an insulin antibody , i.e. insulin, proinsulin , and proinsulin like material . The term is composed of hyper high, proinsulin immature insulin molecule, and emia blood condition. Hyperproinsulinemia is more frequent in type 2 diabetes . It has been attributed to either a direct beta cell &beta cells defect or an indirect effect of cell dysregulation under sustained elevated blood glucose hyperglycemia . Some allele s of insulin can cause hyperproinsulinemia see table 2 http genome.wellcome.ac.uk doc WTD020843.html Genetic disorder Single gene disorder monogenic forms of Diabetes mellitus type 1 type 1 diabetes , INS insulin . For a more detailed descriptions of the insulin gene variations leading to hyperproinsulinemia see NCBI s http www.ncbi.nlm.nih.gov entrez dispomim.cgi?id 176730 OMIM 176730 References reflist Posttranslational modification disorders Category Disorders of endocrine pancreas Category Diabetes pt Hiperproinsulinemia ... more details
taxobox status LR cd status system iucn2.3 status ref   ref Gonz lez Espinosa, M. 1998. http www.iucnredlist.org search details.php 30847 all Guaiacum coulteri . http www.iucnredlist.org 2006 IUCN Red List of Threatened Species. Downloaded on 21 August 2007. ref regnum Plant ae unranked divisio Angiosperms unranked classis Eudicots unranked ordo Rosids ordo Zygophyllales familia Zygophyllaceae genus Guaiacum species G. coulteri binomial Guaiacum coulteri binomial authority Asa Gray A.Gray ref name GRIN cite web url http www.ars grin.gov cgi bin npgs html taxon.pl?444184 title Taxon Guaiacum coulteri A. Gray work Germplasm Resources Information Network publisher United States Department of Agriculture date 2007 05 14 accessdate 2010 10 03 ref Guaiacum coulteri is a species of flowering plant in the Tribulus terrestris caltrop Family biology family , Zygophyllaceae , that is native to western Mexico and Guatemala . ref name GRIN In a rabbit trial of twelve Mexican plants with reputed antidiabetic properties, it was the most effective in reducing hyperglycemia . ref PMID 1308793 ref References Reflist External links commonscat inline Guaiacum coulteri Guaiacum coulteri wikispecies inline Guaiacum coulteri Guaiacum coulteri Category Guaiacum coulteri Category Plants described in 1854 Category Trees of Baja California Category Trees of Chiapas Category Trees of Guatemala Category Trees of Jalisco Category Flora of the State of Mexico Category Trees of Michoac n Category Trees of Nayarit Category Trees of Oaxaca Category Trees of Puebla Category Trees of Sinaloa Category Trees of Sonora rosid stub es Guaiacum coulteri vi Guaiacum coulteri ... more details