9 sub glycosidic bond . Inosine is commonly found in tRNA s and is essential for proper translation of the genetic code in wobble base pair s. Knowledge of inosine metabolism has led to advances in immunotherapy in recent decades. Inosinemonophosphate is oxidised by the enzyme inosinemonophosphate dehydrogenase , yielding xanthosine monophosphate , a key precursor in purine metabolism. Mycophenolate mofetil is an anti metabolite, anti proliferative drug that acts as an inhibitor of inosinemonophosphate ... Adenine is converted to adenosine or inosinemonophosphate IMP , either of which, in turn, is converted into inosine I , which pairs with Adenine A , cytosine C , and uracil U . Purine nucleoside phosphorylase intraconverts inosine and hypoxanthine . Inosine is also an intermediate in a chain ... . For example, inosine and inosine 5 monophosphate have been reported as specific feeding stimulants ... 651. ref The main problem of using inosine and or inosine 5 monophosphate as feeding attractants ... , causing knock out of viral load. See also Inosinemonophosphate dehydrogenase Nucleobase References ... international inosine pregnancy category legal status OTC routes of administration Pharmacokinetic ... stdinchicite correct chemspider StdInChIKey UGQMRVRMYYASKQ KQYNXXCUSA N Inosine is a nucleoside that is formed ... for this purpose showed no improvement. ref cite journal title Inosine supplementation has no effect ... Tarr J author separator , ref It has been shown that inosine has neuroprotective properties. It has been proposed for spinal cord injury ref cite journal title Secondary degeneration reduced by inosine ... observation has shown that axonal re wiring is encouraged. ref cite journal title Inosine induces ... Using Over the Counter Inosine Full Text View ClinicalTrials.gov Bot generated title ref It produces ... s symptoms. The trial uses inosine to raise urate levels in those with levels lower than the population ... biology primer s for polymerase chain reaction , inosine is useful in that it will indiscriminately ... more details
enzyme Name inosine kinase EC number 2.7.1.73 CAS number 37237 46 0 IUBMB EC number 2 7 1 73 GO code 0008906 image width caption In enzymology , an inosine kinase EC number 2.7.1.73 is an enzyme that catalysis catalyzes the chemical reaction ATP inosine math rightleftharpoons math ADP IMP Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and inosine , whereas its two product chemistry products are adenosine diphosphate ADP and Inosinemonophosphate IMP . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP inosine 5 phosphotransferase . Other names in common use include inosine guanosine kinase , and inosine kinase phosphorylating . This enzyme participates in purine metabolism . References reflist 1 cite journal author Pierre KJ, LePage GA date 1968 title Formation of inosine 5 monophosphate by a kinase in cell free extracts of Ehrlich ascites cells in vitro journal Proc. Soc. Exp. Biol. Med. volume 127 pages 432&ndash 40 pmid 5645030 issue 2 enzyme stub Category EC 2.7.1 Category Enzymes of unknown structure ... more details
enzyme Name inosine nucleosidase EC number 3.2.2.2 CAS number 9030 95 9 IUBMB EC number 3 2 2 2 GO code 0047724 image width caption In enzymology , an inosine nucleosidase EC number 3.2.2.2 is an enzyme that catalysis catalyzes the chemical reaction inosine H sub 2 sub O math rightleftharpoons math D ribose hypoxanthine Thus, the two substrate biochemistry substrates of this enzyme are inosine and water H sub 2 sub O , whereas its two product chemistry products are D ribose and hypoxanthine . This enzyme belongs to the family of hydrolase s, specifically those glycosylases that hydrolyse N glycosyl compounds. The systematic name of this enzyme class is inosine ribohydrolase . Other names in common use include inosinase , and inosine guanosine nucleosidase . This enzyme participates in purine metabolism . References reflist 1 cite journal author KOCH AL date 1956 title Some enzymes of nucleoside metabolism of Escherichia coli journal J. Biol. Chem. volume 223 pages 535&ndash 49 pmid 13376622 issue 1 cite journal author Tarr HLA date 1955 title Fish muscle riboside hydrolases journal Biochem. J. volume 59 pages 386&ndash 391 pmid 14363106 issue 3 pmc 1216255 hydrolase stub Category EC 3.2.2 Category Enzymes of unknown structure ... more details
chembox ImageFile Inosine pranobex.png ImageSize 150px IUPACName 9 2 R ,3 R ,4 S ,5 R 3,4 dihydroxy 5 hydroxymethyl oxolan 2 yl 3 H purin 6 one 4 acetamidobenzoic acid 1 dimethylamino propan 2 ol OtherNames Isoprinosine Methisoprinol Section1 Chembox Identifiers ChemSpiderID 16736312 InChI1 1 C10H12N4O5.C9H9NO3.C5H13NO c15 1 4 6 16 7 17 10 19 4 14 3 13 5 8 14 11 2 12 9 5 18 1 6 11 10 8 4 2 7 3 5 8 9 12 13 1 5 7 4 6 2 3 h2 4,6 7,10,15 17H,1H2, H,11,12,18 2 5H,1H3, H,10,11 H,12,13 5,7H,4H2,1 3H3 t4 ,6 ,7 ,10 m0.. s1 InChIKey1 PBJNZCQJMWVIRT MDQYBHOLBR CASNo 36703 88 5 PubChem 37510 KEGG D01995 SMILES CN C CC C O.OC O c1ccc NC C O cc1.Oc3ncnc2c3ncn2 C H 1O C H CO C H O C H 1O ATCCode prefix J05 ATCCode suffix AX05 Section2 Chembox Properties Formula C sub 52 sub H sub 78 sub N sub 10 sub O sub 17 sub MolarMass 1115.23 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Inosine pranobex Isoprinosine or Methisoprinol is a combinatinon of inosine , acetamidobenzoic acid , and dimethylaminoisopropanol used as an antiviral drug . Inosine pranobex has no effect on viral cells itself. It acts as a powerful immunostimulant . It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy, with promising results. Category Antivirals antiinfective drug stub antineoplastic drug stub fr Inosine pranobex ja pl Pranobeks inozyny ... more details
SMILES O P O O OC C H 3O C H n2cnc1c ncnc12 N C H O C H 3O MeSHName Adenosine monophosphate Section2 ... FlashPt Autoignition Adenosine monophosphate AMP , also known as 5 adenylic acid , is a nucleotide ... down by living systems, nucleoside monophosphates, including adenosine monophosphate, are formed. AMP ... P sub i sub ATP this step is most often performed in aerobes by the ATP synthase during oxidative phosphorylation AMP can be converted into inosinemonophosphate IMP by the enzyme myoadenylate deaminase , freeing an ammonia group. In a catabolic pathway, adenosine monophosphate can be converted to uric ... adenosine monophosphate cyclic AMP or cAMP . Within certain cells the enzyme adenylate cyclase ... fr Ad nosine monophosphate gl Adenosina monofosfato ko hr Adenozin monofosfat ... ur Adenosine monophosphate zh ... more details
XVFCMESISA N MeSHName Uridine monophosphate Section2 Chembox Properties Formula C sub 9 sub ... lide Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine monophosphate , also known ... group , the pentose sugar ribose , and the nucleobase uracil hence, it is a ribonucleoside monophosphate ... . Biosynthesis Uridine monophosphate is formed from Orotidine 5 monophosphate orotidylic acid in a decarboxylation ... decarboxylase function is carried out by the protein UMP synthase . ref http www.pubmedcentral.nih.gov articlerender.fcgi?artid 1715274 Analysis of UMP synthase gene and mRNA structure in hereditary orotic aciduria fibroblasts Bot generated title ref Defective UMP synthase can result in orotic ... of uridine monophosphate, choline, and docosahexaenoic acid DHA were found to have significantly ..., July 3, 2008 ref Uridine Monophosphate in Foods In brain research studies such as those mentioned in this article, uridine monophosphate is used as a convenient delivery compound for uridine . Uridine ... or prescription drugs. This is not so. Uridine monophosphate is a major component of RNA . Any food ... DNA RNA Oligonucleotide Pyrimidine biosynthesis Ribonucleoside monophosphate Nucleobases, nucleosides ... fr Uridine monophosphate gl Urid n monofosfato it Uridina monofosfato nl Uridinemonofosfaat ... more details
chembox Verifiedfields changed verifiedrevid 413157820 ImageFile DUMP chemical structure.png ImageSize IUPACName OtherNames dUMP Section1 Chembox Identifiers CASNo Ref cascite correct ?? CASNo 964 26 1 PubChem 688 SMILES ChEMBL Ref ebicite changed EBI ChEMBL 211312 MeSHName 2 deoxyuridine 5 monophosphate Section2 Chembox Properties Formula C sub 9 sub H sub 13 sub N sub 2 sub O sub 8 sub P MolarMass 308.182 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxyuridine monophosphate is a deoxynucleotide . It is an intermediate in the metabolism of deoxyribonucleotide s. See also uridine monophosphate DCMP deaminase Nucleobases, nucleosides, and nucleotides biochem stub Category Nucleotides ca Monofosfat de desoxiuridina fa fr D soxyuridine monophosphate gl Desoxiuridina monofosfato nl Deoxyuridinemonofosfaat ja sr Dezoksiuridin monofosfat ... more details
Refimprove date August 2007 In biochemistry , a synthase is an enzyme that catalyse s a Biosynthesis synthesis process. Following the Enzyme Commission number EC number classification, they belong to the group of lyase s, with ligase s catalysing the reverse reaction. Note that, originally, biochemical nomenclature distinguished synthetases and synthases. Under the original definition, synthases do not use energy from nucleoside triphosphates such as ATP, GTP, CTP, TTP, and UTP , whereas synthetases do use nucleoside triphosphates. However, the Joint Commission on Biochemical Nomenclature JCBN dictates that synthase can be used with any enzyme that catalyzes synthesis whether or not it uses nucleoside triphosphates , whereas synthetase is to be used synonymously with ligase . ref http www.chem.qmul.ac.uk iubmb newsletter misc synthase.html ref Examples ATP synthase Citrate synthase Tryptophan synthase Pseudouridine synthase Fatty acid synthase Cellulose synthase UDP forming Cellulose synthase GDP forming References references Enzymes Category Lyases Enzyme stub de Synthasen fr Synthase lt Sintaz pl Syntazy sv Syntas zh ... more details
Unreferenced date October 2006 Chembox verifiedrevid 447289738 ImageFile Desoxyguanosinmonophosphat protoniert.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo Ref cascite correct CAS CASNo 902 04 5 PubChem 161075 SMILES C1C C OC1N2C NC3 C2NC NC3 O N COP O O O O.N Section2 Chembox Properties Formula C sub 10 sub H sub 14 sub N sub 5 sub O sub 7 sub P MolarMass 347.2243 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxyguanosine monophosphate , also known as deoxyguanylate , or dGMP , is a derivative of the common nucleic acid guanosine triphosphate GTP , in which the OH hydroxyl group on the 2 carbon on the nucleotide s pentose has been reduced to just a hydrogen atom hence the deoxy part of the name . It is used as a monomer in DNA . See also Nucleic acid DNA metabolism Cofactor biochemistry Cofactor Guanosine Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxyguanosine Monophosphate Category Nucleotides ca Monofosfat de desoxiguanosina fa fr D soxyguanosine monophosphate gl Desoxiguanosina monofosfato nl Deoxyguanosinemonofosfaat sr Dezoksiguanozin monofosfat zh ... more details
chembox verifiedrevid 460776176 ImageFile DCMP chemical structure.png ImageSize IUPACName OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 13343 InChI 1 C9H14N3O7P c10 7 1 2 12 9 14 11 7 8 3 5 13 6 19 8 4 18 20 15,16 17 h1 2,5 6,8,13H,3 4H2, H2,10,11,14 H2,15,16,17 t5 ,6 ,8 m0 s1 InChIKey NCMVOABPESMRCP SHYZEUOFBL StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H14N3O7P c10 7 1 2 12 9 14 11 7 8 3 5 13 6 19 8 4 18 20 15,16 17 h1 2,5 6,8,13H,3 4H2, H2,10,11,14 H2,15,16,17 t5 ,6 ,8 m0 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey NCMVOABPESMRCP SHYZEUOFSA N CASNo Ref cascite correct CAS CASNo 1032 65 1 ChEMBL Ref ebicite correct EBI ChEMBL 374699 PubChem 624 ChEBI Ref ebicite correct EBI ChEBI 15918 SMILES c1cn c O nc1N C H 2C C H C H O2 COP O O O O MeSHName Deoxycytidine monophosphate Section2 Chembox Properties Formula C sub 9 sub H sub 14 sub N sub 3 sub O sub 7 sub P MolarMass 307.197 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxycytidine monophosphate , also known as deoxycytidylate , or dCMP , is a deoxynucleotide , and one of the four monomer s that make up DNA . In a DNA double helix, it will base pair with deoxyguanosine monophosphate . Nucleobases, nucleosides, and nucleotides Category Nucleotides biochem stub ca Monofosfat de desoxicitidina fa fr D soxycytidine monophosphate gl Desoxicitidina monofosfato nl Deoxycytidinemonofosfaat sr Dezoksicitidin monofosfat zh ... more details
Unreferenced date October 2006 Chembox verifiedrevid 447288275 ImageFile DAMP chemical structure.png ImageSize IUPACName OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 12079 InChI 1 C10H14N5O6P c11 9 8 10 13 3 12 9 15 4 14 8 7 1 5 16 6 21 7 2 20 22 17,18 19 h3 7,16H,1 2H2, H2,11,12,13 H2,17,18,19 t5 ,6 ,7 m0 s1 InChIKey KHWCHTKSEGGWEX RRKCRQDMBS StdInChI Ref stdinchicite correct chemspider StdInChI 1S C10H14N5O6P c11 9 8 10 13 3 12 9 15 4 14 8 7 1 5 16 6 21 7 2 20 22 17,18 19 h3 7,16H,1 2H2, H2,11,12,13 H2,17,18,19 t5 ,6 ,7 m0 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey KHWCHTKSEGGWEX RRKCRQDMSA N CASNo Ref cascite correct CAS CASNo 653 63 4 PubChem 621 ChEBI Ref ebicite correct EBI ChEBI 17713 SMILES c1nc c2c n1 n cn2 C H 3C C H C H O3 COP O O O O N MeSHName Deoxyadenosine monophosphate Section2 Chembox Properties Formula C sub 10 sub H sub 14 sub N sub 5 sub O sub 6 sub P MolarMass 331.222 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Context article date October 2009 Deoxyadenosine monophosphate , also known as deoxyadenylate , or dAMP , is a derivative of the common nucleic acid AMP, or adenosine monophosphate , in which the OH hydroxyl group on the 2 carbon on the nucleotide s pentose has been reduced to just a hydrogen atom hence the deoxy part of the name . Deoxyadenosine monophosphate is abbreviated dAMP. It is a monomer used in DNA . See also Nucleic acid DNA metabolism Cofactor biochemistry Cofactor Guanosine Cyclic AMP cAMP Adenosine Triphosphate ATP Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxyadenosine Monophosphate Category Nucleotides Biochemistry stub ca Monofosfat de desoxiadenosina fa fr D soxyad nosine monophosphate gl Desoxiadenosina monofosfato nl Deoxyadenosinemonofosfaat ja sr Dezoksiadenozin monofosfat zh ... more details
group group , the pentose sugar ribose , and the nucleobase cytosine hence, a ribonucleoside monophosphate ... DNA RNA Oligonucleotide Ribonucleoside monophosphate References reflist 2 Nucleobases, nucleosides, and nucleotides DEFAULTSORT Cytidine Monophosphate Category Nucleotides Category Pyrimidones Biochem ... fr Cytidine monophosphate gl Citid n monofosfato it Citosina monofosfato nl Cytidinemonofosfaat ... more details
s, thymidine monophosphate does not contain the deoxy prefix in its name. ref cite ... es Timidilato fa fr Thymidine monophosphate gl Desoxitimidina monofosfato nl ... more details
enzyme Name Adenylosuccinate synthase EC number 6.3.4.4 CAS number 9023 57 8 IUBMB EC number 6 3 4 4 GO code 0004019 image width caption Infobox protein family Symbol Adenylsucc synt Name Adenylsucc synt image PDB 1dj3 EBI.jpg width caption structures of adenylosuccinate synthetase from triticum aestivum and arabidopsis thaliana Pfam PF00709 Pfam clan CL0023 InterPro IPR001114 SMART PROSITE PDOC00444 MEROPS SCOP 1ade TCDB OPM family OPM protein CAZy CDD In molecular biology, Adenylosuccinate synthase or adenylosuccinate synthetase EC number 6.3.4.4. is an enzyme that plays an important role in purine biosynthesis, by catalysing the guanosine triphosphate GTP dependent conversion of inosinemonophosphate IMP and aspartic acid to guanosine diphosphate GDP , phosphate and N 6 1,2 dicarboxyethyl AMP. Adenylosuccinate synthetase has been characterised from various sources ranging from Escherichia coli gene purA to vertebrate tissue biology tissue s. In vertebrates, two isozymes are present one involved in purine biosynthesis and the other in the purine nucleotide cycle. Structure The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right handed crossover connections between the strands. The 10th strand is Antiparallel biochemistry antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta sheets, composed of two strands and three strands each, 11 alpha helix alpha helices and two short 3 10 helices. Further, it has been suggested that the similarities ... synthase isozymes protein Name adenylosuccinate synthase caption image width HGNCid 292 Symbol ADSS ... 1 Arm q Band 44 LocusSupplementaryData protein Name adenylosuccinate synthase like 1 caption image ... Adenylosuccinate synthase References reflist InterPro content IPR001114 ligase stub Ligases Nucleotide ... more details
chembox verifiedrevid 395738406 ImageFile Orotidine monophosphate.svg ImageSize IUPACName 3 2R,3R,4S,5R 3,4 dihydroxy 5 & 8203 phosphonooxymethyl oxolan 2 yl & 8203 2,6 dioxo pyrimidine 4 carboxylic acid OtherNames Orotidylic acid, br OMP Section1 Chembox Identifiers CASNo 2149 82 8 PubChem 968 SMILES C1 C N C O NC1 O C2C C C O2 COP O O O O O C O O MeSHName Orotidine 5 monophosphate Section2 Chembox Properties Formula C sub 10 sub H sub 13 sub N sub 2 sub O sub 11 sub P MolarMass 368.191 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Orotidine 5 monophosphate OMP , also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate . OMP is formed from orotic acid orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase In humans, the enzyme UMP synthase converts OMP into uridine 5 monophosphate . If UMP synthase is defective, orotic aciduria can result. Nucleotide metabolism intermediates Category Nucleotides Category Pyrimidinediones biochem stub fa ja 5 sr Orotidin 5 monofosfat ... more details
Inosine 5 monophosphate dehydrogenase IMPDH is an essential cytoplasmic purine metabolic enzyme that catalyzes the NAD dependent oxidation of inosinemonophosphate IMP to xanthosine monophosphate XMP , the first and rate limiting step towards the synthesis of GTP from IMP. IMPDH has an essential role in providing precursors for DNA and RNA bioysynthesis. IMPDH also plays a role in signal transduction pathways that mediate cell differentiation. As purine metabolism is largely conserved across all known organisms, so is the structure and function of IMPDH. IMPDH from pathogenic bacterium Streptococcus pyogenes to human crystallizes as a tetramer . ref name pmid10200156 cite journal doi 10.1021 bi982858v title Characteristics and Crystal Structure of Bacterial Inosine 5 monophosphate Dehydrogenase year 1999 last1 Zhang first1 Rong Guang last2 Evans first2 Gwyndaf last3 Rotella first3 Frank J. last4 Westbrook first4 Edwin M. last5 Beno first5 Don last6 Huberman first6 Eliezer last7 Joachimiak first7 Andrzej last8 Collart first8 Frank R. journal Biochemistry volume 38 issue 15 pages 4691 700 pmid 10200156 ref IMPDH expression is found to be upregulated in tumor tissues and tumor cell lines. ref name pmid1356621 cite journal pmid 1356621 year 1992 last1 Collart first1 FR last2 Chubb first2 CB last3 Mirkin first3 BL last4 Huberman first4 E title Increased inosine 5 phosphate dehydrogenase gene expression in solid tumor tissues and tumor cell lines volume 52 issue 20 pages 5826 8 journal Cancer research ref ref name pmid9752721 cite journal doi 10.1016 S0079 6603 08 60827 2 title Inosine 5 Monophosphate Dehydrogenase Regulation of Expression and Role in Cellular Proliferation and T Lymphocyte Activation journal Progress in Nucleic Acid Research and Molecular Biology year 1998 last1 ... JL title Inosine 5 monophosphate dehydrogenase is a rate determining factor for p53 dependent growth ... Lecture volume 43 issue 8 pages 3466 92 journal Cancer research ref See also Ribonucleoside monophosphate ... more details
Molybdopterin synthase is an enzyme required to sythesize molybdenum cofactor MoCo from precursor Z now known as cyclic pyranopterin monophosphate . It is heterodimeric and coded for by the MOCS2 gene. ref cite journal last1 Sloan first1 J last2 Kinghorn first2 JR last3 Unkles first3 SE title The two subunits of human molybdopterin synthase evidence for a bicistronic messenger RNA with overlapping reading frames journal Nucleic Acids Research volume 27 issue 3 pages 854 8 year 1999 pmc 148257 pmid 9889283 doi 10.1093 nar 27.3.854 ref References reflist Category Enzymes biochem stub ... more details
DP title Localization of the gene for uridine monophosphatesynthase to human chromosome region 3q13 ... monophosphatesynthase to human chromosome region 3q13 by in situ hybridization journal Genomics ... monophosphatesynthase journal Biochemistry volume 19 issue 20 pages 4699 706 year 1981 pmid 6893554 ... of uridine monophosphatesynthase UMPS gene to river buffalo chromosomes by FISH journal Chromosome ...PBB geneid 7372 Uridine monophosphate synthetase UMPS orotate phosphoribosyl transferase and orotidine 5 decarboxylase is the enzyme EC number 4.1.1.23 that catalyses the formation of uridine monophosphate ... web title Entrez Gene UMPS uridine monophosphate synthetase orotate phosphoribosyl transferase and orotidine ... sites catalyze the last two steps of the de novo uridine monophosphate UMP biosynthetic pathway. After addition of ribose P to orotate by OPRTase to form orotidine 5 monophosphate OMP , OMP is decarboxylated to form uridine monophosphate by ODCase. In microorganisms, these two domains are separate ..., uridine monophosphate synthetase. ref name Jones 1980 Jones, M. E. 1980 Annu. Rev. Biochem. 49 ... activities, with the UMP synthase monomer displaying low decarboxylase activity, and only the 5.6 ... of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria ... Shanks RD, Robinson JL title Embryonic mortality attributed to inherited deficiency of uridine monophosphatesynthase journal J. Dairy Sci. volume 72 issue 11 pages 3035 9 year 1989 month November ... WP1601 highlight Uridine monophosphate synthetase See also orotidine 5 phosphate decarboxylase ... UMP synthase journal Adv. Exp. Med. Biol. volume 253A issue pages 511 8 year 1990 pmid 2624233 ... coding region of human UMP synthase journal Proc. Natl. Acad. Sci. U.S.A. volume 85 issue ... and initial characterization of the single polypeptide that synthesizes uridine 5 monophosphate from ... Suchi M, Mizuno H, Kawai Y, et al. title Molecular cloning of the human UMP synthase gene and characterization ... more details
enzyme Name phosphatidylcholine synthase EC number 2.7.8.24 CAS number 243666 86 6 IUBMB EC number 2 7 8 24 GO code 0050520 image width caption In enzymology , a phosphatidylcholine synthase EC number 2.7.8.24 is an enzyme that catalysis catalyzes the chemical reaction CDP diacylglycerol choline math rightleftharpoons math CMP phosphatidylcholine Thus, the two substrate biochemistry substrates of this enzyme are CDP diacylglycerol and choline , whereas its two product chemistry products are cytidine monophosphate CMP and phosphatidylcholine . This enzyme belongs to the family of transferase s, specifically those transferring non standard substituted phosphate groups. The systematic name of this enzyme class is CDP diacylglycerol choline O phosphatidyltransferase . This enzyme is also called CDP diglyceride choline O phosphatidyltransferase . This enzyme participates in glycerophospholipid metabolism . References reflist 1 cite journal author de Rudder KE, Sohlenkamp C, Geiger O date 1999 title Plant exuded choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase journal J. Biol. Chem. volume 274 pages 20011&ndash 6 pmid 10391951 doi 10.1074 jbc.274.28.20011 issue 28 cite journal author Sohlenkamp C, de Rudder KE, Rohrs V, Lopez Lara IM, Geiger O date 2000 title Cloning and characterization of the gene for phosphatidylcholine synthase journal J. Biol. Chem. volume 275 pages 18919&ndash 25 pmid 10858449 doi 10.1074 jbc.M000844200 issue 25 enzyme stub Category EC 2.7.8 Category Enzymes of unknown structure ... more details
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