In Riemannian geometry , the cut locus of a point math p math in a manifold is roughly the set of all other points for which there are multiple minimizing geodesic geodesics connecting them from math p math , but it may contain additional points where the minimizing geodesic is unique, under certain circumstances. The distance function from p is a Smooth function smooth function except at the point p itself and the cut locus. Definition Fix a point math p math in a complete space complete Riemannian manifold math M,g math , and consider the tangent space math T pM math . It is a standard result that for sufficiently small math v math in math T p M math , the curve defined by the exponential map Riemannian geometry Riemannian exponential map , math gamma t exp p tv math for math t math belonging to the interval math 0,1 math is a geodesic minimizing geodesic , and is the unique minimizing ... math . The cut locus of math p math in the tangent space is defined to be the set of all vectors math ... locus of math p math in math M math is defined to be image of the cut locus of math p math in the tangent space under the exponential map at math p math . Thus, we may interpret the cut locus ... math stop being minimizing. The least distance from p to the cut locus is the injectivity radius at p ... Suppose math q math is in the cut locus of math p math in math M math . A standard result ref Petersen ... , the cut locus of a point consists of the single point opposite of it i.e., the antipodal point . On an infinitely long cylinder geometry cylinder , the cut locus of a point consists of the line opposite the point. Applications The significance of the cut locus is that the distance function from a point math p math is smooth, except on the cut locus of math p math . In particular, it makes sense to take the gradient and Hessian matrix Hessian of the distance function away from the cut locus ... theorems in Riemannian geometry. Cut locus of a subset One can similarly define the cut locus ... more details
Infobox Defunct Company company name Locus Computing Corporation company logo Better Living Through Transparency ... , Chief technical officer CTO and chairman. industry Software products LOCUS operating system LOCUS ... Acquired by Platinum Technology Inc. successor Platinum Technology Locus Computing Corporation was formed ... ai n17443977 title Locus Computing Corp. company profile accessdate 2008 09 23 Dead link date September 2010 bot RjwilmsiBot ref to commercialize the technologies developed for the LOCUS operating system LOCUS distributed computing distributed operating system at UCLA . Locus was notable for commercializing ... the use of DOS and Windows 3.1 software on Unix systems. Locus was acquired by Platinum Technology ... technology And Locus Computing Finalize Acquisition Locus Computing officially becomes a PLATINUM ... PS 2 and System 370 Locus was commissioned by IBM to produce a version of the AIX UNIX based operating system for the PS 2 and System 370 ranges. The single system image capabilities of LOCUS operating system LOCUS were incorporated under the name of AIX TCF transparent computing facility . ref cite web title IBM TAPS LOCUS FOR KEY AUX UNIX FEATURES, TCF FILE SYSTEM url http www.cbronline.com news ibm taps locus for key aux unix features tcf file system accessdate 2008 10 06 ref OSF 1 AD for the Intel Paragon Locus was commissioned by Intel to produce a multiprocessor version of OSF 1 for the Intel ... the TCF technology from LOCUS operating system LOCUS as Transparent Network Computing , or TNC, inventing ... NonStop Clusters Locus was commissioned by Tandem Computers to include their TNC technology in a High ... Las Vegas, Nev.? oclc 48259379 ref During the course of the project Locus was acquired by Platinum ... project. Merge Merge software Merge was a system developed by Locus in late 1984 for the AT&T ... SCO Unix . Locus eventually joined the Microsoft Windows Interface Source Environment WISE ref ... of Windows. ref cite web url http www.thefreelibrary.com Locus announces availability of Merge 3.2 ... more details
Infobox OS name LOCUS developer UCLA family Unix source model Closed source working state Historic kernel type Monolithic kernel license Proprietary software Proprietary LOCUS was a distributed operating system developed at UCLA during the 1980s. It was notable for providing an early implementation of the single system image idea, where a cluster computing cluster of machines appeared to be one larger machine. ref cite web title The LOCUS Distributed Operating System url http www.cs.princeton.edu courses archive fall03 cs518 papers locus.pdf author Bruce J. Walker Walker, Bruce year 1983 doi 10.1145 800217.806615 ref A desire to commercialize the technologies developed for LOCUS inspired the creation of the Locus Computing Corporation which went on to include ideas from LOCUS in various products, including Tru64 UNIX OSF 1 AD OSF 1 AD and, finally, the Santa Cruz Operation SCO Tandem Computers Tandem UnixWare NonStop Clusters product. Description The LOCUS system was created at UCLA between 1980 and 1983, initial implementation was on a cluster of PDP 11 45s using 1 and 10 megabit token ... space across all nodes. The development of LOCUS was supported by an DARPA ARPA research contract, DSS ... LOCUS used replication computer science replication , the data of files could be stored on more than one node and LOCUS would keep the various copies up to date. This provided particularly good ... file LOCUS would nominate one node as the current synchronization site CSS for a particular file system ... dependent files As with other Single system image SSI systems LOCUS sometimes found it necessary to break .... For example it was possible to build a LOCUS cluster containing both PDP 11 45 and VAX 750 machines ... . Devices LOCUS provided remote access to I O devices. Yes, do go on Processes LOCUS provided a single ... node the process would be run. LOCUS was designed to work with heterogeneous nodes, e.g. a mix ... node communication, including named pipe s, Partitioning The LOCUS system was designed to be able ... more details
Infobox album See Wikipedia WikiProject Albums Name Locus Solus Type studio Artist John Zorn Cover Locus Solus album .jpg Released 1983 re released 1990 and 1997 Recorded 1983 Genre Avant garde music avant garde , jazz , contemporary classical music classical Length 68 37 Label Rift, Eva Wave, Tzadik Records Tzadik Producer John Zorn Chronology John Zorn Last album Archery album Archery br 1982 This album Locus Solus br 1983 Next album Yankees album Yankees br 1983 Misc Extra album cover Upper caption Original Rift Records Cover Type studio Cover Locus Solus Rift .jpg Lower caption Locus Solus is an album of improvisations by John Zorn and other musicians. Originally released as a double vinyl album on Rift records in 1983 it was re released as a CD with additional tracks on Eva Wave in 1990 and on Zorn s Tzadik Records label in 1997. ref http www.tzadik.com index.php?catalog 7303 Tzadik catalogue ref Reception The Allmusic review by Joslyn Layne awarded the album 3 stars stating This captures over an hour s worth of John Zorn s search for the improvised song form.... Overall, an album of short, angular, experimental energy tracks . ref name Allmusic Layne, J. http www.allmusic.com album locus solus r150722 Allmusic Review accessed July 22, 2011 ref Album ratings rev1 Allmusic rev1Score rating 3 5 ref name Allmusic Track listing Bass and the Treble 2 57 Acquisition and Control of Fire 1 33 Honey Cab 2 33 Switch 2 15 Juan Takes It Out of His System 2 11 The Wish 2 02 A Case Arose 2 00 The Elf 1 41 Getting Curly 1 51 Don t Switch 1 50 Smooth Cheeks of a Big Ego 1 51 Add Water ... Say Never Again 1 45 Sign of the Four 2 13 Locus Solus, Pt. 1 2 2 11 Where Are My Victims? 2 06 ... tracks 23 30 Whiz Kid turntables tracks 31 38 References reflist DEFAULTSORT Locus Solus Album Category John Zorn albums Category Tzadik Records albums Category 1983 albums cs Locus Solus album fr Locus Solus album ... more details
Orphan date October 2008 The locus of enterocyte effacement LEE is a moderately conserved pathogenicity island consisting of 35,000 base pairs in the bacteria Escherichia coli genome. The LEE encodes the Type III secretion system and associated chaperones and effector proteins responsible for attaching and effacing AE lesions in the large intestine. These proteins include intimin , Tir , EspC , EspF , EspH , and Map protein . The LEE has a 38 G C ratio. Category Cell biology cell biology stub ... more details
The human globin locus is composed of five gene s located on a short region of Chromosome 11 human chromosome 11 , responsible for the creation of the beta parts roughly half of the oxygen transport protein Hemoglobin . This locus contains not only the HBB beta globin gene but also HBD delta , HBG1 gamma A , HBG2 gamma G , and HBE1 epsilon globin. Expression of all of these genes is controlled by single locus control region LCR , and the genes are differentially expressed throughout development. ref name pmid11895428 cite journal author Levings PP, Bungert J title The human beta globin locus control region journal Eur. J. Biochem. volume 269 issue 6 pages 1589 99 year 2002 month March pmid 11895428 doi 10.1046 j.1432 1327.2002.02797.x url ref The order of the genes in the beta globin cluster is 5 HBE1 epsilon HBG2 gamma G HBG1 gamma A HBD delta HBB beta 3 . The arrangement of the genes directly reflects the temporal differentiation of their expression during development, with the early embryonic stage version of the gene located closest to the LCR. If the genes are rearranged, the gene products are expressed at improper stages of development. References Reflist Further reading Refbegin 2 cite journal author Frischknecht H, Dutly F title A 65 bp duplication insertion in exon II of the beta globin gene causing beta0 thalassemia journal Haematologica volume 92 issue 3 pages 423 4 year 2007 month March pmid 17339197 url doi 10.3324 haematol.10785 cite journal author Giardina B, Messana I, Scatena R, Castagnola M title The multiple functions of hemoglobin journal Crit. Rev. Biochem. Mol. Biol. volume 30 issue 3 pages 165 96 year 1995 pmid 7555018 url doi 10.3109 10409239509085142 cite journal author Higgs DR, Vickers MA, Wilkie AO, Pretorius IM, Jarman AP, Weatherall DJ title A review of the molecular genetics of the human alpha globin gene cluster journal Blood volume 73 ... Locus Category Chromosomes Category Hemoglobins genetics stub de Globin Locus ... more details
Locus control regions LCR are defined by their ability to enhance the expression of linked genes to physiological levels in a tissue specific and copy number dependent manner at ectopic chromatin sites. ref name Li2002 cite journal author Li Q, Peterson KR, Fang X, Stamatoyannopoulos G title Locus control regions journal Blood volume 100 issue 9 page 3077 3086 year 2002 month November pmid 12384402 doi 10.1182 blood 2002 04 1104 url http www.bloodjournal.org cgi pmidlookup?view long&pmid 12384402 pmc 2811695 ref The concept derives from the idea that developmental and cell lineage specific regulation of gene expression relies not only on gene proximal elements such as Promoter biology promoter s, Enhancer genetics enhancer s, and Silencer DNA silencer s, but also on long range interactions of various cis regulatory elements and dynamic chromatin alterations. The LCR was identified over 20 years ago. In transgenic mouse studies it was determined that the LCR was required for normal regulation of Beta globulins beta globin gene expression. ref name Gerstein2007 cite journal author Gerstein MB, Bruce C, Rozowsky JS, et al. title What is a gene, post ENCODE? History and updated definition journal Genome Res. volume 17 issue 6 page 669 681 year 2007 month June pmid 17567988 doi 10.1101 gr.6339607 url http genome.cshlp.org cgi pmidlookup?view long&pmid 17567988 ref Several models exist for how the LCR exerts its effects on transcription from a distance. Looping model LCR section of the DNA loops around to different extent over the desired gene of expression, so that the binding site of the transcriptional machinery proteins is in physical close proximity to bridge and affect the transcription of that specific gene. References Reflist genetics stub Category Epigenetics fr R gion de contr le du locus ... more details
Flowering Locus C ref name pmid10330478 Citation author Michaels SD, Amasino RM title FLOWERING LOCUS C encodes a novel MADS domain protein that acts as a repressor of flowering journal Plant Cell volume 11 issue 5 pages 949 56 year 1999 pmid 10330478 doi 10.1105 tpc.11.5.949 pmc 144226 postscript . ref FLC is a MADS box gene that in late flowering ecotypes of the plant Arabidopsis thaliana is responsible for vernalization . In a new seedling FLC is Gene expression expressed , which prevents flowering. Upon exposure to cold, less FLC is expressed to a degree depending on the amount of cold , and flowering becomes possible. ref citation doi 10.1073 pnas.060023597 year 2000 month Mar author Sheldon, Cc Rouse, Dt Finnegan, Ej Peacock, Wj Dennis, Es title The molecular basis of vernalization the central role of FLOWERING LOCUS C FLC . volume 97 issue 7 pages 3753 8 pmid 10716723 pmc 16312 journal Proceedings of the National Academy of Sciences of the United States of America url http www.pnas.org cgi pmidlookup?view long&pmid 10716723 format Free full text ref FLC is extensively regulated through epigenetic modifications and transcriptional control. The expression of FLC is affected by other genes including FLK plant gene FLK , ref citation doi 10.1105 tpc.019331 year 2004 month Mar author Lim, Mh Kim, J Kim, Ys Chung, Ks Seo, Yh Lee, I Kim, J Hong, Cb Kim, Hj Park, Cm title A new Arabidopsis gene, FLK, encodes an RNA binding protein with K homology motifs and regulates flowering time via FLOWERING LOCUS C. volume 16 issue 3 pages 731 40 pmid 14973162 pmc 385284 journal The Plant cell url http www.plantcell.org cgi pmidlookup?view long&pmid 14973162 format Free full text ref FCA plant gene FCA ref name sheldon and VERNALIZATION2 VRN2 . ref name sheldon citation doi 10.1105 tpc.004564 ... of FLOWERING LOCUS C and for the Epigenetic Maintenance of Repression year 2002 author Sheldon ..., Kc Amasino, Rm title Attenuation of FLOWERING LOCUS C activity as a mechanism for the evolution ... more details
Locus Reference Genomic LRG ref name LRG paper http genomemedicine.com content 2 4 24 Paper in Genome Medicine describing LRGs ref ref name NG editorial http www.nature.com ng journal v42 n5 abs ng0510 363.html Editorial in Nature Genetics about LRGs ref is a DNA sequence format that was developed to aid in curating locus specific databases LSDBs that record DNA Mutation sequence variation which can result in inherited diseases. LRGs have fixed sequences that are independent of the genome so that they provide a stable framework for reporting variants. The LRG format uses extensible markup language XML to provide highly structured single records containing the genomic DNA sequence for individual gene s along with the mRNA s and protein s encoded by these genes. LRG records are recommended in the http www.hgvs.org mutnomen Human Genome Variation Society Nomenclature guidelines as reference sequences to report sequence variants in LSDBs and the literature. The Mutalyzer 2 sequence nomenclature checker can check sequence variant descriptions using LRGs. The LRG concept was developed by the http www.gen2phen.org GEN2PHEN project in conjunction with the European Bioinformatics Institute EBI and the National Center for Biotechnology Information NCBI . The http www.lrg sequence.org LRG homepage provides access to existing LRG sequences and allows the submission of requests for the creation of new LRGs. This page also has a frequently asked questions FAQ s section. References Reflist External links http www.lrg sequence.org The LRG homepage http www.mutalyzer.nl The Mutalyzer homepage Category Genomics genetics stub ... more details
Infobox nrhp name Locus 7 Site nrhp type image Locus 7 Site.jpg caption Overview of the site location North of Fayette City, Pennsylvania ref name nomination cite web title National Register of Historic Places Inventory&mdash Nomination Form Locus 7 Site author Michael, Ronald L. publisher National Park Service date July 16, 1979 url http www.arch.state.pa.us pdfs H000869 01B.pdf format PDF accessdate December 29, 2009 ref lat degrees 40 lat minutes 6 lat seconds 23.88 lat direction N long degrees 79 long minutes 50 long seconds 12.9 long direction W coord display inline,title coord parameters region US type landmark locmapin Pennsylvania architect architecture added March 20, 1980 area convert 2.9 acre governing body Private refnum 80003495 ref name nris NRISref 2009a ref The Locus 7 Site is an archaeological site in Washington Township, Fayette County, Pennsylvania Washington Township , Fayette County, Pennsylvania Fayette County , Pennsylvania , United States . Located north of Fayette City, Pennsylvania Fayette City , the site lies on a bluff over Downers Run cref a about convert 2000 ft from the Monongahela River . cref b It is believed to be the location of a former Monongahela tribe Monongahela village, but its date is uncertain the village may have existed at any time between 900 and 1600. ref name nomination rp 2 Its location on a bluff is unusual for Monongahela village sites, but this may have contributed to its preservation most riverside Monongahela sites in the valley of the Monongahela River have been destroyed by development. ref name nomination rp 3 Small scale archaeological investigation at the site has revealed a wide range of pottery at the site, along with a significant amount of mussel shells it is believed that a more extensive excavation would yield evidence of small round houses and a stockade . ref name nomination rp 2 Such a large amount of potential ... who used only horse powered equipment. ref name nomination rp 3 Locus 7 s archaeological significance ... more details
PBB geneid 2778 GNAS complex locus , also known as GNAS , is a protein which in humans is encoded by the GNAS gene . The protein encoded by this gene is the stimulatory G protein alpha subunit Gs alpha subunit G sub s sub , a key component of many signal transduction pathways. Gene This gene locus genetics locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5 exons. Some transcripts contains a differentially methylated region DMR at their 5 exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript exists, and this antisense transcript and one of the transcripts are paternally expressed, produce noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein. The GNAS locus is imprinted and encodes 5 main transcripts Gs alpha subunit G sub s sub XLAS NESP55 A B transcript antisense GNAS transcript Protein Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G protein alpha subunit Gs alpha subunit G sub s sub , a key element of the classical signal transduction pathway linking receptor ligand interactions with the activation of adenylyl cyclase and a variety of cellular responses. Multiple transcript variants have been found for this gene, but the full length nature and or biological validity of some ... locus url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 2778 accessdate ... type Ia pseudopseudohypoparathyroidism McCune Albright syndrome Interactions GNAS complex locus ... journal author Bastepe M, J ppner H title GNAS locus and pseudohypoparathyroidism. journal Horm ... author J ppner H, Bastepe M title Different mutations within or upstream of the GNAS locus cause distinct ... more details
involved locus are thought to be additive. Writers have distinguished this kind of inheritance as polygenic ... than one locus. When more than one gene is involved with or without the presence of environmental ... one would choose to determine etiology. Quantitative trait locus Image Example of QTL Scan .... Consequently, many QTLs are associated with a single trait. A quantitative trait locus QTL is a region ... analysis qg Use dmy dates date November 2010 DEFAULTSORT Quantitative Trait Locus Category Classical genetics Category Genetics Category Statistical genetics de Quantitative Trait Locus es QTL fr Locus ... trait locus nl Kwantitatieve vererving ja pl QTL ru fi ... more details
Winners of the Locus Award for Best Young Adult Book , awarded by the Locus magazine. Awards presented in a given year are for works published in the previous calendar year. The award for Best Young Adult Book was first presented in 2003, and is among the awards still presented. Winners are as follows ref name WWE LYA cite web url http www.worldswithoutend.com books locus ya index.asp title Locus YA Award Winners & Nominees work Worlds Without End accessdate 2011 11 4 ref class wikitable sortable Year Novel Author 2003 Coraline Neil Gaiman 2004 The Wee Free Men Terry Pratchett 2005 A Hat Full of Sky Terry Pratchett 2006 Pay the Piper A Rock N Roll Fairy Tale Jane Yolen & Adam Stemple 2007 Wintersmith Terry Pratchett 2008 Un Lun Dun China Mi ville 2009 The Graveyard Book Neil Gaiman 2010 Leviathan Westerfeld novel Leviathan Scott Westerfeld 2011 Ship Breaker Paolo Bacigalupi See also Locus Award References reflist External Links http www.worldswithoutend.com books locus ya index.asp Graphical listing of awards and nominees with excerpts and synopses Worlds Without End http www.locusmag.com SFAwards Db Locus.html Official Locus Awards page Category Lists of award winners Category Science fiction awards Category American literary awards Category Young adult book awards ... more details
Locus Award for Best Fantasy Novel is one of the awards given by Locus Magazine . class wikitable Year Novel Author 1978 The Silmarillion J. R. R. Tolkien 1980 Harpist in the Wind Patricia A. McKillip 1981 Lord Valentine s Castle Robert Silverberg 1982 The Claw of the Conciliator Gene Wolfe 1983 The Sword of the Lictor Gene Wolfe 1984 The Mists of Avalon Marion Zimmer Bradley 1985 Job A Comedy of Justice Robert A. Heinlein 1986 Trumps of Doom Roger Zelazny 1987 Soldier of the Mist Gene Wolfe 1988 Seventh Son Orson Scott Card 1989 Red Prophet Orson Scott Card 1990 Prentice Alvin Orson Scott Card 1991 Tehanu The Last Book of Earthsea Ursula K. Le Guin 1992 Beauty fantasy novel Beauty Sheri S. Tepper 1993 Last Call novel Last Call Tim Powers 1994 The Innkeeper s Song Peter S. Beagle 1995 Brittle Innings Michael Bishop author Michael Bishop 1996 Alvin Journeyman Orson Scott Card 1997 A Game of Thrones George R. R. Martin 1998 Earthquake Weather novel Earthquake Weather Tim Powers 1999 A Clash of Kings George R. R. Martin 2000 Harry Potter and the Prisoner of Azkaban J. K. Rowling 2001 A Storm of Swords George R. R. Martin 2002 American Gods Neil Gaiman 2003 The Scar China Mi ville 2004 Paladin of Souls Lois McMaster Bujold 2005 Iron Council China Mi ville 2006 Anansi Boys Neil Gaiman 2007 The Privilege of the Sword Ellen Kushner 2008 Making Money Terry Pratchett 2009 Lavinia novel Lavinia ... See also Locus Award External links http www.locusmag.com SFAwards Db LocusWinsByCategory.html nvlf The Locus Award Index Fantasy http www.locusmag.com News 2011 06 locus awards 2011 winners The Locus Award 2011 winners http www.worldswithoutend.com books locus f index.asp Excerpts and summaries of all Locus winning and nominated fantasy novels Locus Award Best Fantasy Novel Category Lists of award winners Category Science fiction awards Link FL ru fr Prix Locus du meilleur roman de fantasy ja ro Premiul Locus pentru cel mai bun roman n genul fantezie ru ... more details
Winners of the Locus Award for Best SF Novel , awarded by the Locus magazine Locus magazine. Awards presented in a given year are for works published in the previous calendar year. The award for Best SF Novel was first presented in 1980, and is among the awards still presented as of 2008 . Previously, there had simply been an award for Locus Award for Best Novel Best Novel . An award for Locus Award for Best Fantasy Novel Best Fantasy Novel was also introduced in 1980. Winners class wikitable Year Winner style vertical align top 1980 Titan John Varley Titan by John Varley author John Varley style vertical align top 1981 The Snow Queen novel The Snow Queen by Joan D. Vinge style vertical align top 1982 The Many Coloured Land by Julian May style vertical align top 1983 Foundation s Edge by Isaac Asimov style vertical align top 1984 Startide Rising by David Brin style vertical align top 1985 The Integral Trees by Larry Niven style vertical align top 1986 The Postman by David Brin style vertical align top 1987 Speaker for the Dead by Orson Scott Card style vertical align top 1988 The Uplift War by David Brin style vertical align top 1989 Cyteen by C. J. Cherryh style vertical align top 1990 Hyperion Simmons novel Hyperion by Dan Simmons style vertical align top 1991 The Fall of Hyperion by Dan Simmons style vertical align top 1992 Barrayar by Lois McMaster Bujold style vertical align top 1993 Doomsday Book novel Doomsday Book by Connie Willis style vertical align top 1994 Green Mars ... SFAwards Db Locus.html Locus Magazine web site http www.worldswithoutend.com books locus sf index.asp List of all winning and nominated novels Locus Award Best SF Novel state expanded DEFAULTSORT Locus Award For Best Science Fiction Novel Category Science fiction awards Category American literary awards Link FL ru fr Prix Locus du meilleur roman de science fiction ja SF ro Premiul Locus pentru cel mai bun roman science fiction ru ... more details
Winners of the Locus Award for Best First Novel , awarded by the Locus magazine. Awards presented in a given year are for works published in the previous calendar year. The award for Best First Novel was first presented in 1981, and is among the awards still presented as of 2010 . class wikitable Year Novel Author 1981 Dragon s Egg Robert L. Forward 1982 Starship & Haiku Somtow Sucharitkul 1983 Courtship Rite Donald Kingsbury 1984 Tea with the Black Dragon R. A. MacAvoy 1985 Three Californias Trilogy The Wild Shore Kim Stanley Robinson 1986 Contact novel Contact Carl Sagan 1987 The Hercules Text Jack McDevitt 1988 War for the Oaks Emma Bull 1989 Desolation Road Ian McDonald author Ian McDonald 1990 Orbital Decay Allen Steele 1991 In the Country of the Blind Michael F. Flynn 1992 The Cipher Kathe Koja 1993 China Mountain Zhang Maureen F. McHugh 1994 Cold Allies Patricia Anthony 1995 Gun, with Occasional Music Jonathan Lethem 1996 The Bohr Maker Linda Nagata rowspan 2 1997 tie Reclamation novel Reclamation Sarah Zettel Whiteout Sage Walker novel Whiteout Sage Walker 1998 The Great Wheel Ian R. MacLeod 1999 Brown Girl in the Ring novel Brown Girl in the Ring Nalo Hopkinson 2000 The Silk Code Paul Levinson 2001 Mars Crossing Geoffrey A. Landis 2002 Kushiel s Dart Jacqueline Carey 2003 A Scattering of Jades Alexander C. Irvine 2004 Down and Out in the Magic Kingdom Cory Doctorow 2005 Jonathan Strange & Mr Norrell Susanna Clarke 2006 Hammered novel Hammered Scardown Worldwired Elizabeth Bear 2007 Temeraire series Temeraire His Majesty s Dragon br Throne of Jade Black Powder War Naomi Novik 2008 Heart Shaped Box novel Heart Shaped Box Joe Hill writer Joe Hill 2009 Singularity s Ring ... See also Locus Award References http www.locusmag.com SFAwards Db LocusWinsByCategory.html http www.locusmag.com News 2011 06 locus awards 2011 winners Locus Award Best First Novel Category Lists of award ... awards fr Prix Locus du meilleur premier roman ja ru ... more details
Wiktionary redirect Short pages monitor This long comment was added to the page to prevent it being listed on Special Shortpages. It and the accompanying monitoring template were generated via Template Longcomment. Please do not remove the monitor template without removing the comment as well. ... more details
Unreferenced stub auto yes date December 2009 Orphan date November 2006 Context date October 2009 An orphon is a nonfunctional gene located outside the main chromosomal locus genetics locus . Category Genetics Sci stub ... more details
In geometry , the Thomson cubic of a triangle is the locus mathematics locus of centers of circumconic s whose normals at the Vertex geometry vertices are concurrent lines concurrent . References mathworld title Thomson cubic urlname ThomsonCubic Category Triangle geometry nl Kubische kromme van Thomson ... more details
Genetic Heterogeneity is a phenomenon in which a single phenotype or genetic disorder may be caused by any one of a multiple number of alleles or non allele locus genetics locus mutations. ref Turnpenny and Ellard, Emery s Elements of Medical Genetics, 13th Edition. Elsevier Limited, 2007. ISBN 978 0 7020 2917 2 ref This is in contrast to pleiotropy , where a single gene may cause multiple phenotypic expressions or disorders. Genetic heterogeneity can be classified as either allelic or locus . Allelic heterogeneity means that different mutations within a single gene locus forming multiple alleles of that gene cause the same phenotypic expression. For example, there are over 1000 known mutant alleles of the CFTR gene CFTR gene that cause cystic fibrosis . Locus heterogeneity means that variations in completely unrelated gene Locus genetics loci cause a single disorder. For example, retinitis pigmentosa has autosomal dominant , autosomal recessive , and X linked origins. However, only one mutant locus is needed for the phenotype to manifest. References reflist Category Classical genetics genetics stub it Eterogeneit genetica ... more details
Hypervariable may refer to Hypervariable sequence , a segment of a chromosome characterised by considerable variation in the number of tandem repeat s at one or more loci Hypervariable locus , a locus with many allele s especially those whose variation is due to variable numbers of tandem repeats Hypervariable region HVR , a chromosomal segment characterized by multiple alleles within a population for a single genetic locus disambig Category Genetics ... more details
Michael Flynn br Virginia Heinlein ref name locus 2003 cite web url http locusmag.com SFAwards Db Heinlein2003.html title The Locus Index to SF Awards 2003 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate September 21, 2011 ref 2004 Arthur C. Clarke ref name locus 2004 cite web url http locusmag.com SFAwards Db Heinlein2004.html title The Locus Index to SF Awards 2004 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate September 21, 2011 ref 2005 Larry Niven br Jerry Pournelle ref name locus 2005 cite web url http locusmag.com SFAwards Db Heinlein2005.html title The Locus Index to SF Awards 2005 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate September 21, 2011 ref 2006 Greg Bear br Jack Williamson ref name locus 2006 cite web url http locusmag.com SFAwards Db Heinlein2006.html title The Locus Index to SF Awards 2006 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate September 21, 2011 ref 2007 Anne McCaffrey br Elizabeth Moon ref name locus 2007 cite web url http locusmag.com SFAwards Db Heinlein2007.html title The Locus Index to SF Awards 2007 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate September 21, 2011 ref 2008 Ben Bova br Spider Robinson ref name locus 2008 cite web url http locusmag.com SFAwards Db Heinlein2008.html title The Locus Index to SF Awards 2008 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate September 21, 2011 ref 2009 Joe Haldeman br John Varley ref name locus 2009 cite web url http locusmag.com SFAwards Db Heinlein2009.html title The Locus Index to SF Awards 2009 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate September 21, 2011 ref 2010 not awarded 2011 Connie Willis ref name locus news 2011 cite web url http www.locusmag.com News 2011 09 willis wins 2011 robert a heinlein award title Willis Wins 2011 Robert A. Heinlein Award publisher Locus magazine Locus Online accessdate ... more details
Image PCWmice1.jpg thumb right Genes which control hair colour are polymorphic. A gene is said to be polymorphic if more than one allele occupies that gene s Locus genetics locus within a population. ref http www.biology online.org dictionary Genetic polymorphism ref Examples of polymorphic genes DRD2 ANKK1 COMT MAOA References reflist Category Genetics ... more details
Reading 1981 Terry Carr Awards The anthology placed first in the 1983 Locus Award Locus Poll ... in the 1982 Locus Award Locus Poll Award for Best Novella . Walk the Ice placed thirteenth in the 1982 Locus Award Locus Poll Award for Best Short Story . The Pusher was nominated for the 1981 Nebula ... Hugo Award for Best Short Story , and placed first in the 1982 Locus Award Locus Poll Award for Best ... seventeenth in the 1982 Locus Award Locus Poll Award for Best Short Story . Walden Three placed twenty first in the 1982 Locus Award Locus Poll Award for Best Novelette . Second Comings Reasonable Rates placed eighteenth in the 1982 Locus Award Locus Poll Award for Best Short Story . Forever placed fourteenth in the 1982 Locus Award Locus Poll Award for Best Short Story . Emergence won the 1981 ... twelfth in the 1982 Locus Award Locus Poll Award for Best Novella . The Woman the Unicorn Loved was nominated fore the 1982 Hugo Award for Best Short Story and placed sixth in the 1982 Locus Award Locus Poll Award for Best Short Story . Serpent s Teeth placed second in the 1982 Locus Award Locus Poll Award for Best Short Story . The Thermals of August was nominated for the 1981 Nebula Award for Best Novelette and the 1982 Hugo Award for Best Novelette , and placed third in the 1982 Locus Award Locus Poll Award for Best Novelette . Going Under was nominated for the 1981 Nebula Award for Best Short Story and placed twenty third in the 1982 Locus Award Locus Poll Award for Best Novelette ... for Best Short Story , and placed eighth in the 1982 Locus Award Locus Poll Award for Best Short Story ... in the 1982 Locus Award Locus Poll Award for Best Novella . External links isfdb title id 34176 title ... more details
Locus Award Locus Poll Award for Best Anthology . The Pope of the Chimps was nominated for the 1982 Nebula Award for Best Short Story and placed twelfth in the 1983 Locus Award Locus Poll Award ... Hugo Award for Best Novelette , and placed sixth in the 1983 Locus Award Locus Poll Award for Best ... for Best Novella and the 1983 SF Chronicle Award for Best Novella , and placed first in the 1983 Locus Award Locus Poll Award for Best Novella . Burning Chrome was nominated for the 1982 Nebula Award for Best Novelette and placed seventeenth in the 1983 Locus Award Locus Poll Award for Best Novelette . Farmer on the Dole placed sixteenth in the 1983 Locus Award Locus Poll Award for Best Novelette . Meet Me At Apogee placed twenty seventh in the 1983 Locus Award Locus Poll Award for Best Short ... Locus Award Locus Poll Award for Best Short Story . Understanding Human Behavior was nominated for the 1982 Nebula Award for Best Novelette and placed tenth in the 1983 Locus Award Locus Poll Award for Best Novelette . Relativistic Effects placed nineteenth in the 1983 Locus Award Locus Poll Award for Best ... Award for Best Short Fiction , and placed fourth in the 1983 Locus Award Locus Poll Award for Best ... more details
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