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Neurofibromatosis type I
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Encyclopedia results for Neurofibromatosis type I

Neurofibromatosis type I





Encyclopedia results for Neurofibromatosis type I

  1. Neurofibromatosis type I

    I, Tong JJ, Zhu Y, Nurnberg P, Zhong Y title Effect of neurofibromatosis type I mutations on a novel ... LQ, Parada LF title Tumor microenvironment and neurofibromatosis type I connecting the GAPs journal ... bifida Radiographically, Neurofibromatosis type I Dural ectasia Dural ectasia can lead to scalloping ... signaling peptides and proteins DEFAULTSORT Neurofibromatosis Type I Category Deficiencies ... Typ 1 es Neurofibromatosis fr Neurofibromatose de type I nl Ziekte van Von Recklinghausen ... Infobox Disease Name Neurofibromatosis type 1 ICD10 ICD10 Q 85 0 q 80 ILDS Q85.010 ICD9 ICD9 ... mult eMedicine2 neuro 248 eMedicine2 oph 338 eMedicine2 radio 474 MeshID D009456 Neurofibromatosis type I NF 1 , formerly known as Friedrich Daniel von Recklinghausen von Recklinghausen disease ... R, et al. title cDNA cloning of the type 1 neurofibromatosis gene complete sequence of the NF1 ... Neurofibromatosis type 1 peripheral nerve tumors aberrant activation of the Ras pathway journal ... The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin ... ther neuro klesse.pdf Current Therapies for Neurofibromatosis Type 1 , by Laura Klesse MD PhD, Mountain ... characteristics of children with neurofibromatosis type 1 journal Am. J. Med. Genet. A volume ... title Motor deficits in neurofibromatosis type 1 mice the role of the cerebellum journal Genes Brain ...&rank 1 Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type ... and emotional problems in children with neurofibromatosis type 1 evidence and proposed interventions ... 17. ref name autogenerated1 cite journal author Goldberg NS, Collins FS title The hunt for the neurofibromatosis ... autogenerated2 cite journal author Gutmann DH, Giovannini M title Mouse models of neurofibromatosis ... type or 1 plexiform neurofibroma Freckling in the axillary region axillary or inguinal region disambiguation ... for the disorder itself. Instead, people with neurofibromatosis are followed by a team ...   more details



  1. Neurofibromatosis type 3

    Infobox disease Name Neurofibromatosis type 3 Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 601321 MedlinePlus eMedicineSubj eMedicineTopic MeshID Neurofibromatosis type 3 also known as Neurofibromatosis mixed type resembles von Recklinghausen s disease , but also presents with cutaneous neurofibromas. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 552 References reflist See also Neurofibromatosis Skin lesion Category Genodermatoses Genodermatoses stub ...   more details



  1. Neurofibromatosis type 4

    Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 162270 MedlinePlus eMedicineSubj eMedicineTopic MeshID Neurofibromatosis type 4 also known as Neurofibromatosis variant type resembles von Recklinghausen s disease , but also presents with cutaneous neurofibromas. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 552 This is a new development in the NF family. See also Neurofibromatosis Skin lesion References reflist Genodermatoses stub Category Genodermatoses ...   more details



  1. Neurofibromatosis type II

    Infobox disease Name Neurofibromatosis type II Image Schwannoma Antoni A and B very high mag.jpg Caption Micrograph of a schwannoma , a tumor seen in neurofibromatosis type II. HPS stain . DiseasesDB 8960 ... NF2.PNG right 50px thumb NF 2 Locus Neurofibromatosis Type II or MISME Syndrome , for Multiple Inherited ... is about 1 in 60,000. ref name pmid19545378 cite journal author Evans DG title Neurofibromatosis type ... to result in the tumors characteristic of Neurofibromatosis type II. The NF II gene is presumed ... Type 2 eMedicine Radiology cite web url http emedicine.medscape.com article 342667 overview title Neurofibromatosis Type 2 eMedicine Radiology format work accessdate 2010 12 20 ref Progression ... with neurofibromatosis type 2 journal Clin Neurol Neurosurg volume 111 issue 5 pages 454 9 year ... peptides and proteins DEFAULTSORT Neurofibromatosis Type Ii Category Neurological disorders Category ... The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell ... included in studies that were designed to compare disease type and progression with exact determination ..., a diagnostic procedure should be performed to decide which form of neurofibromatosis causes the alterations ... hearing loss. The http nfcenter.wustl.edu St. Louis Children s Hospital Neurofibromatosis Center ... General Hospital used the cancer drug Bevacizumab commercial name Avastin to treat 10 patients with neurofibromatosis type II. The result was published in The New England Journal of Medicine . Of the ten ... studied for treatment of meningioma which is associated with Neurofibromatosis . ref http clinicaltrials.gov ... Allen at NYU Langone Medical Center for treatment of vestibular schwannoma in Neurofibromatsis type ... fluid Ear Cerebellum Neurofibromatosis Mutation Gene References Reflist External links General ... NCBI NIH UW entry on Neurofibromatosis 2 http www.sfn.org Society for Neuroscience Description of surgical ... House Ear Institute Research Advocacy Children s Tumor Foundation Ending Neurofibromatosis Through ...   more details



  1. Neurofibromatosis

    neurofibromas are a cause of morbidity in the affected individuals. main Neurofibromatosis type I Neurofibromatosis ... prenatal tests for the neurofibromatoses? ref To detect Neurofibromatosis type I . To detect Neurofibromatosis ... a 15 month old child who turned out to have Neurofibromatosis type I was misdiagnosed as being abused ... to have been affected with neurofibromatosis type I. However, it is possible Merrick suffered from ... mult OMIM2 101000 MedlinePlus eMedicineSubj derm eMedicineTopic 287 MeshID D017253 Neurofibromatosis commonly abbreviated NF neurofibromatosis type 1 is also known as von Recklinghausen disease is a genetic .... It affects males and females equally. Classification Neurofibromatosis type 1 NF 1 Image Neurofibromatosis ... it more common than neurofibromatosis type 2, with a frequency of 1 in 45,000 people. ref name kap ..., meningiomas , glioma s and pheochromocytoma s. hydrocoele early puberty Neurofibromatosis type 2 NF 2 main Neurofibromatosis type II Neurofibromatosis type 2 also called central neurofibromatosis ... to diagnose, and eventually find a prognosis for. Other variants Neurofibromatosis type 3 Neurofibromatosis type 4 Neurofibromatosis type 5 Citation needed date January 2012 Related disorders Neurofibromatosis ... type I NF 1 and NF 2 may be inherited in an autosomal dominant fashion, as well as through random mutation. Neurofibromatosis type 1 is caused by mutation on chromosome 17 q11.2, the gene ... Medicine Small textbook edition 16 pages 2453 ref Neurofibromatosis type 2 is due to mutation ... of the Ras kinase pathway p21 oncoprotein . ref cite journal title Neurofibromatosis Type 1 Peripheral ... type I and Legius syndrome . Testing includes DNA sequencing and Multiplex ligation dependent probe ...Infobox disease Name Neurofibromatosis Image Neurofibromatosis.jpg Caption Back of an elderly woman with neurofibromatosis ... 3 isbn 978 0 7817 9516 6 ref ref name ka Neurofibromatosis is an autosomal dominant disorder, which ... parent has neurofibromatosis, his or her children have a 50 chance of developing the condition as well ...   more details



  1. Type I keratin

    Type I keratins or Type I cytokeratins constitutes the Type I intermediate filaments IFs of the intracytoplasmatic cytoskeleton, which is present in all mammalian epithelial cells. Most of the type I keratins consist of acidic, low molecular weight protein s which in vivo are arranged in pairs of heterotypic Type I and Type II keratin chains, coexpressed during differentiation of simple and stratified epithelial tissues. Type I keratins are encoded on chromosome 17q and encompasses K9, K10, K11, K12, K13, K14, K15, K16, K17, K18, K19 and K20. Their molecular weight ranges from 40 kDa K19 to 64 kDa K9 . See also Type II keratin External links MeshName Type I Keratin Category Keratins protein stub Cytoskeletal Proteins Fibrous proteins fr Cytok ratines de type I ...   more details



  1. Motorola Type I

    Unreferenced date December 2009 Motorola Type I Is the original type of Motorola s Trunked radio system it is based on Fleets and Subfleets. Each system had a certain number of Fleets assigned, and then each Fleet had a certain number of Subfleets and radio IDs. The distribution of Fleets and Subfleets on a Type I system is determined by the system Fleetmap. Motorola Type I systems are not scalable because they limit the amount of IDs any fleet or subfleet can support. Each Type I ID appears as a three or four digit number, followed by a hyphen, followed by a one or two digit number example 200 14 . The term Privacy Plus refers to a Type I system. Privacy Plus systems are normally older public safety systems and Specialized Mobile Radio SMR s. Trunked radio systems Category Trunked radio systems ...   more details



  1. Type I hair keratin

    Unreferenced stub auto yes date December 2009 Type I hair keratin is one of the two types of hair keratin . It is an acidic protein which heterodimerize s with type II hair keratin s to form hair and nail anatomy nail s. Fibrous proteins DEFAULTSORT Type I Hair Keratin Category Keratins Protein stub fr Exok ratines de type I ...   more details



  1. Type I pneumocyte

    Infobox Anatomy Name PAGENAME Latin GraySubject GrayPage Image Caption Image2 Caption2 Precursor System Artery Vein Nerve Lymph MeshName MeshNumber Code TerminologiaHistologica 3 05 02.0.0028 Type I pneumocyte s simple squamous alveolar cells are responsible for gas exchange in the alveoli and cover a majority of the alveolar surface area 95 . While type I pneumocytes account for most of the surface area, they are approximately half as numerous as Type II pneumocyte type II cells , due to differences in size. Type II pneumocytes are large round cells, while type I pneumocytes are smaller cells stretched across a large surface area. Type I pneumocytes are unable to mitosis replicate and are susceptible to toxin toxic insults. In the event of damage, Type II cells can proliferate and or differentiate into type I cells to compensate. cell biology stub respiratory stub Lower respiratory system anatomy Human cell types derived primarily from endoderm Category Lung anatomy Category Human cells ar ja I pt Pneum cito tipo I ...   more details



  1. Type-I collagen

    protein Name collagen, type I, alpha 1 caption image width HGNCid 2197 Symbol COL1A1 AltSymbols EntrezGene 1277 OMIM 120150 RefSeq NM 000088 UniProt P02452 PDB ECnumber Chromosome 17 Arm q Band 21.3 LocusSupplementaryData q22 protein Name collagen, type I, alpha 2 caption image width HGNCid 2198 Symbol COL1A2 AltSymbols OI4 EntrezGene 1278 OMIM 120160 RefSeq NM 000089 UniProt P08123 PDB ECnumber Chromosome 7 Arm q Band 21.3 22.1 LocusSupplementaryData Type I collagen is the most abundant collagen of the human body. It is present in scar tissue , the end product when tissue healing heals by repair. It is found in tendon s, the endomysium of myofibrils and the organic part of bone . See also Collagen Type II collagen Collagen, type III, alpha 1 COL1A1 COL1A2 External links MeshName Collagen type I Fibrous proteins Category Collagens gene 17 stub ca Col lagen tipus I ...   more details



  1. Type I string theory

    that type I string theory with the string coupling constant math g math is equivalent to the SO 32 heterotic .... 339 arXiv hep th 0204089 . DEFAULTSORT Type I String Theory Category String theory String theory stub es Tipo I teor a de cuerdas fr Th orie des cordes de type I it Teoria di stringa tipo I lt I ...Unreferenced stub auto yes date December 2009 String theory cTopic Theory In theoretical physics , type I string theory is one of five consistent supersymmetric string theory string theories in ten dimensions. It is the only one whose strings are unoriented both orientations of a string are equivalent and which contains not only closed string s, but also open string s. The classic 1976 work of Ferdinando Gliozzi , Joel Scherk and David Olive paved the way to a systematic understanding of the rules behind string spectra in cases where only closed string s are present via modular invariance but did not lead to similar progress for models with closed strings, despite the fact that the original discussion was based on the type I string theory. As first proposed by Augusto Sagnotti in 1987, the type I string theory can be obtained as an orientifold of type IIB string theory, with 32 half D9 brane s added in the vacuum to cancel various anomaly physics anomalies . At low energies, type I string theory is described by the N 1 supergravity type I supergravity in ten dimensions coupled to the SO 32 supersymmetric Yang Mills theory . The discovery in 1984 by Michael Green physicist Michael Green and John H. Schwarz that anomalies in type I string theory cancel sparked the first superstring revolution . However, a key property of these models, shown by A. Sagnotti in 1992, is that in general the Green Schwarz mechanism takes a more general form, and involves several two forms in the cancellation mechanism. The relation between the type IIB string theory and the type I string theory has a large number of surprising consequences, both in ten and in lower dimensions, that were first displayed ...   more details



  1. Type I Rifle

    Unreferenced date September 2008 Infobox Weapon is ranged yes image Image Type I Rifle.jpg 300px caption name Type I Rifle type Infantry Service Rifle origin flagicon Italy 1861 Kingdom of Italy 1861 1946 Kingdom of Italy era World War II design date 1939 prod design date serv design date 1939 1945 used by Flag Empire of Japan 1944 wars World War II spec type caliber 6.5 mm cart length 800 mm cartridge 6.5mm Arisaka feed 5 round action bolt rate c.30 RPM velocity 765 m s 2,509.2 ft s weight 3.95 kg length 1,280 mm range variants Rifle only number 60,000 The Type I rifle was produced by Kingdom of Italy 1861 1946 Italy for the Japanese Empire prior to World War II . After the invasion of China, all Arisaka production was required for use of the Imperial Army, so under the terms of the Anti Comintern Pact , the Imperial Navy contracted with Italy for this weapon in 1937. The Type I is based on the Type 38 rifle and utilizes a Carcano action, but retains the Arisaka Mauser type 5 round box magazine . The Type I was utilized primarily by Japanese Imperial Naval Forces. It is chambered for the 6.5 x 50 mm cartridge. Approximately 120,000 Type I rifles were produced by Italian arsenals for Japan between 1937 through 1939. On the collector market in the United States, the Type I rifle is uncommon but not particularly popular among collectors. Since the heritage of the Type I rifle is both Japanese and Italian, it tends to be shunned by collectors of Japanese focus. The Type I also lacks the Japanese Imperial Imperial Seal of Japan Chrysanthemum markings, or other markings that typically interest collectors of Japanese militaria. Many Type I rifles brought back to the United States as War Trophies were reportedly captured at Kwajalein Atoll , the Philippines , or from Japan at the conclusion of hostilities. Japanese WWII infantry weapons Category Bolt action rifles Category World War II Japanese infantry weapons es Fusil Tipo 1 ja zh ...   more details



  1. Type 2 Ho-I

    Infobox Weapon name Type 2 Ho I image Image ype 2 Ho I gun tank.jpg 300px caption Type 2 Ho I gun tank ... 75 mm Type 99 Gun secondary armament 1 x 7.7 mm Type 97 machine gun armour 12 50 mm engine Mitsubishi Type 100 air cooled br V 12 diesel engine diesel engine power 240 hp 179 kW pw ratio crew 5 The nihongo Type 2 Gun tank Ho I Ni shiki h sensha Ho I Support Tank was a derivative of the Type ... fortifications. ref name History of War http www.historyofwar.org articles weapons type 2 ho i.html History of War ref History and development Design work on the Type 2 Ho I began in 1937, after experience ... of the Type 2 Ho I was a Type 99 75  mm tank gun, and secondary armament was a single 7.7  mm Type 97 Light Machine Gun in the hull. The short barreled 75  mm Type 99 Gun was mounted in a fully rotating two man gun turret . The Type 2 Ho I utilized the chassis of the Type 1 Chi He , which was itself a modified Type 97 Chi Ha. Combat record Production was hampered by material shortages ..., the Type 2 Ho I never saw combat. ref name History of War References cite book last Foss first Christopher year 2003 title Great Book of Tanks The World s Most Important Tanks from World War I to the Present ... Notes reflist WWIIJapaneseAFVs Category Tank destroyers of World War II Category Medium tanks Type 2 Ho I Category World War II Japanese tanks 2 Ho I nl Type 2 Ho I ja pl Typ 2 Ho I ru ... up with the rest of an armored formation, the Japanese began work on mounting a Type 41 75 mm Mountain Gun Type 41 75  mm Mountain Gun onto the chassis of the Chi Ha medium tank. The adapted mountain gun, known as the Type 99 7.5 cm Tank Gun, was completed in 1940. By 1942, with the start of World ... Stuart tanks, which they could barely cope with. The design parameters on the Type 2 were then changed ... Type 2 Ho Is were conversions from existing Type 97 Chi Ha medium tanks. The Tokyo factory of Mitsubishi ... tanks japan ft2hoi.htm Specifications at OnWar http www.historyofwar.org articles weapons type 2 ho ...   more details



  1. Type I hypersensitivity

    Infobox disease Name Type I hypersensitivity Image Misc pollen.jpg Caption Scanning electron microscope SEM of miscellaneous plant pollen s. Pollens are very common allergens. DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D006969 Type I hypersensitivity or immediate hypersensitivity is an allergic reaction provoked by reexposure to a specific type of antigen referred to as an allergen . ref eMedicine med 1101 ref Type I is not to be confused with Type II hypersensitivity Type II , Type III hypersensitivity Type III , or Type IV hypersensitivity Type IV hypersensitivities. Exposure may be by ingestion , inhalation , injection medicine injection , or direct contact. Pathophysiology In type 1 hypersensitivity, an antigen is presented to CD4 Th2 cells specific to the antigen that stimulate B cell production of IgE antibodies also specific to the antigen. The difference between a normal infectious immune response and a type 1 hypersensitivity response is that in type 1 hypersensitivity the antibody is IgE instead of IgA, IgG, or IgM. During sensitization, the IgE antibodies bind to Fc receptors on the surface of tissue mast cells and blood basophils. ref name urlThe Adaptive Immune System Type I Immediate Hypersensitivity cite web url http student.ccbcmd.edu courses bio141 lecguide unit5 hypersensitivity type1 type1.html title The Adaptive Immune System Type I Immediate Hypersensitivity work accessdate 2008 09 22 ref Mast cells and basophils coated .... Type 1 hypersensitivity can be further classified into an immediate and late phase reaction. The immediate ... wikitable Overview of mediators released by mast cells in type 1 hypersensitivity, and their actions ... External links http www.1lec.com Immunology IgE 20Mediated 20 Type 20I 20Hypersensitivity index.html Type I hypersensitivity Flash Animation Hypersensitivity and autoimmune diseases Category Type 1 hypersensitivity es Hipersensibilidad tipo I uk ...   more details



  1. German Type I submarine

    convert 105 mm in abbr on gun br 1 convert 20 mm in abbr on AA Ship armor Ship notes The Type I U boat was the first post World War I attempt by the Germany German Kriegsmarine to produce an ocean going submarine. Only two Type IAs were built, but the decision to halt production on further boats is believed to be because of political decisions and not because of major faults in the Type I design ... War II Allied warships. List of Type I submarines German submarine U 25 1936 U 25 German submarine .... Refend Type I U boats WWIIGermanShips Uboat DEFAULTSORT German Type I Submarine Category Type I U boats Category Submarine classes Type 001 Category World War II submarines of Germany Type 001 be ca U Boot tipus I de U Boot Klasse I fr Unterseeboot type I it U Boot Tipo I hu I t pus n met tengeralattj r nl Type I U boot ja U I pl Okr ty podwodne typu IA ru I sv Ub tsklass Typ I vi T u ng m Ki u 1 zh I ... caption Ship class Ship type Ship displacement 862 tons surfaced br 982 tons submerged Ship length ... due to their poor stability and slow dive rate. The type was based on the design of the Finnish Vetehinen class submarine Finnish Vetehinen class and the Spanish Type E 1 submarine Spanish Type E 1 , designed ... Type VII submarine VII and German Type IX submarine IX classes. Constructed by AG Weser in Bremen city Bremen , the Type IA was launched on February 14, 1936. The two boats produced, German submarine ... References Reflist Refbegin cite web title U Boat Aces.com work U Boat Types &ndash Type IA U Boat url http www.uboataces.com uboat type ia.shtml accessdate July 31, 2006 cite web title U boat.net work U Boat Types &ndash Type IA url http www.uboat.net types ia.htm accessdate July 31, 2006 Gordon ...   more details



  1. Blackburn Type I

    page content for recommended layout. Infobox Aircraft Begin name Type I image caption Infobox Aircraft ... from Blackburn Type D variants with their own articles The Blackburn Type I was a single engine ... seaplane pilotage. Development The first Type I ref name AJJ harvnb Jackson 1968 pages 89 93 ref ref ... deeply committed to aviation and the result was the brief for the Type I. The Type I was of identical .... ref name AJJ File Blackburn Type I.jpg left thumb The first Blackburn Type I with inverted V kingpost. This shows the original full cowling. The Type I was first flown on or shortly after ... decking. ref name AJJ A second Type I was built as a single seater with a freight compartment in place ... War , p.48. Schiffer Military History. ref . Since these two Type I machines had flown rather well, Blackburn produced the Improved Type I first seen ref Flight 28 March 1914 ref at the Olympia Aero ... in this guise on 26 October 1915. ref name AJJ Operational history The Type I was initially used in a mixed ... only air racing success with the Yorkshire built Type I in a 100  mi 160  km circuit via ... on 2 October 1913. The Type I was piloted by Harold Blackburn with Dr. Christie as passenger the Avro ... joy rides on the first Type I ref According to Jackson both Type Is were used at this meeting. However ... the first Type I. The photograph in Blackburn Aircraft since 1909 , purportedly of Blackburn delivering newspapers to Chesterfield in the single kingpost Type I, was more likely taken during the Yorkshire ... saboteurs. The second Type I was flown by Harold Blackburn through the winter of 1913 4. A trip ... Type I was also commandeered by the Government at the start of the war, but having no military ... Type I original two seat development of Type D. Two built, the second a single seater with a freight ... had a single kingpost. Improved Type I revised cowling and tailplane, other minor differences. One built. Land sea monoplane Improved Type I machine fitted with floats, dual control and 100  hp 75 ...   more details



  1. Oculocutaneous albinism type I

    Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 203100 MedlinePlus eMedicineSubj eMedicineTopic MeshID Oculocutaneous Albinism Type I or &ndash Type 1A OCA1A ref name omim OMIM 203100 ref is an autosome autosomal dominance genetics recessive skin disease associated with albinism . This type of albinism is caused when the gene OCA1 gene OCA1 does not function properly. The Locus genetics location of OCA1 may be written as 11q1.4 q2.1 , meaning it is on the long arm of chromosome chromosome 11 human 11 , somewhere in the range of sub band 4 of band 1, and sub band 1 of band 2. References reflist genetic disorder stub Category Autosomal recessive disorders ...   more details



  1. Interferon type I

    Image 1AU1 Human Interferon Beta01.png thumb 200px The 3D structure of human IFN Human type I interferon s comprise a vast and growing group of IFN proteins. All type I IFNs bind to a specific cell surface receptor complex known as the IFN receptor Interferon alpha beta receptor IFNAR that consists of IFNAR1 and IFNAR2 chains. Homologous molecules to type I IFNs are found in many species, including all mammals, and some have been identified in birds, reptiles, amphibians and fish species. ref Schultz et al., The interferon system of non mammalian vertebrates. Developmental and Comparative Immunology ..., also known as limitin . ref Oritani and Tomiyama, Interferon limitin Novel type I Interferon ... 80, pages 325 331 . ref ref Hardy et al., Characterization of the type I interferon locus and identification ... IFN subtypes IFN This subtype of Type I IFN was recently described as a pseudogene in human .... Its presence on the edge of the Type I IFN locus in mammals may have shielded it from ... identified as being the most potent producers of type I IFNs in response to antigen, and have thus ... types Avian Type I IFNs have been characterized and preliminarily assigned to subtypes IFN I, IFN II ... of avian genomes. Functional lizard Type I IFNs can be found in lizard genome databases. Turtle Type I IFNs have been purified references from 1970s needed . They resemble mammalian homologs. The existence of amphibian Type I IFNs have been inferred by the discovery of the genes encoding their receptor chains. They have not yet been purified, or their genes cloned. Piscine bony fish Type I IFN ... Type I IFN genes contain introns, in similar positions as do their orthologs, certain interleukins. References reflist External links MeshName Interferon Type I Interferons DEFAULTSORT Interferon Type I Category Cytokines Category Antivirals Category Immunostimulants ja I sr Interferon tip I ...   more details



  1. Type I and type II errors

    cases, free of error. Two types of error are distinguished type  I error and type  II error . Type I error This section is linked from Type I error A type  I error , also known as an error ... H sub 0 sub . A type  I error may be compared with a so called false positive in other test situations. Type I errors are philosophically a focus of skepticism and Occam s razor . Type  I error ... I error. Type II error This section is linked from Type II error A type  II error , also ... center Type  II error br False negative Understanding Type I and Type II errors From the Bayesian ... Consequences of type I and type II errors Both types of errors are problems for individuals, corporations ... Type III errors anchor Type IV errors Since the paired notions of type  I errors or false positives ... that point where the probabilities of False Reject Type I error and False Accept Type II error are approximately ... Type I And Type Ii Errors Category Design of experiments Category Error Category Hypothesis testing ... simple Type I and type II errors uk zh ... statistical tests sensitivity and specificity too technical date December 2011 Type  I error or, error ... was incorrectly rejected Type  I error or where one fails to reject a false null hypothesis ... PA455&dq type ii error skepticism&source bl&ots bCBz8JJBTo&sig FpB 13Igea9cS40ZZkP8CiAwxm8&hl en&ei 3M4rTfq1EsWblgeK8oj Cw&sa X&oi book result&ct result&resnum 5&ved 0CDQQ6AEwBA v onepage&q type 20ii ... I error is called the size of the test and denoted by the Greek letter math alpha math ... null hypothesis math alpha math is the probability of a type  I error. If the null hypothesis ... test situations. Due to the credulity a type II error isn t made often. Type  II error can ... we actually call type  I or type  II error depends directly on the null hypothesis. Negation of the null hypothesis causes type  I and type  II errors to switch roles. The goal of the test ...   more details



  1. Type 89 I-Go

    SCROLL DOWN TO EDIT THE ARTICLE Infobox Weapon name Type 89 I Go Chi Ro image Image Type 89 Yi Go at Tsuchira.jpg 300px caption A restored Type 89 I Go at Tsuchiura GSDF Base open day origin flag Empire ... Type 89 medium tank I Go Hachiky shiki ch sensha I g was a medium tank used by the Imperial ... left thumb 220px Type 89 I Go on display at the United States Army Ordnance Museum . Design ... was referred to as Niseko steel , an abbreviation of Ni hon se i ko sho. The Type 89 was driven through ... of 29 6 in a reverse L shape. Variants nihongo Type 89A I Go K The initial production ... China northern China . A total of 220 units were produced. nihongo Type 89B I Go Otsu ... formed its first independent armor force by creating three regiments armed with the Type 89 I Go, each ... Typ 89 I g es Tipo 89 I Go ko 89 it Type 89 carro armato nl Type 89 Chi Ro ja pl Typ ... armament 57 mm Type 90 gun br 100 rounds secondary armament 2 x 6.5 mm Type 91 machine gun br hull, coaxial ... of Khalkhin Gol Khalkhin Gol against the Soviet Union , and in the Second World War . The Type ... primarily of Vickers export models, Germany German Panzer I s, and Italy Italian L3 33 CV33 tankettes . ref Zaloga 2007 p. 12 ref The Type 89 was a 1920s design medium tank, built to support the infantry .... The Great Book of Tanks ref The code designation I Go comes from the katakana letter for first ... 45 , p.  90. ref History and development The Type 89 evolved from Japan s first domestic light ..., the new light tank design was finished and designated as the Type 89. The prototype of the Type 89 light tank 1 was completed in April 1929. Later, the Type 89 was re classified as a medium ... 90. ref Production of the Type 89 began in 1931 and it soon became the main tank of the Imperial Japanese Army . Although the Type 89 was well regarded by the Japanese army, there were several small ... to enter the turret. Work continued on improving the Type 89 after the production started, and as a result ...   more details



  1. Fibronectin type I domain

    Pfam box Symbol Fibrnctn1 Name Fibronectin, type I Pfam PF00039 InterPro IPR000083 SMART SM00058 PROSITE PDOC00965 PDB PDB 1e88 PDB 1e8b PDB 1fbr PDB 1o9a PDB 1qgb PDB 1qo6 PDB 1tpg PDB 1tpm PDB 1tpn PDB 2fn2 Fibronectin, type I repeats are one of the three repeats found in the fibronectin protein. Fibronectin is a plasma protein that binds cell surfaces and various compounds including collagen , fibrin , heparin , DNA, and actin . Type I domain FN1 is approximately 40 residues in length. Four conserved cysteines are involved in disulfide bond s. The 3D structure of the FN1 domain has been determined ref name PUB00004065 cite journal author Campbell ID, Baron M, Norman D, Willis A title Structure of the fibronectin type 1 module journal Nature volume 345 issue 6276 pages 642 646 year 1990 pmid 2112232 doi 10.1038 345642a0 ref ref name PUB00003289 cite journal author Driscoll PC, Harvey TS, Campbell ID, Baron M, Dudgeon TJ, Downing AK, Smith BO title Solution structure of the fibrin binding finger domain of tissue type plasminogen activator determined by 1H nuclear magnetic resonance journal J. Mol. Biol. volume 225 issue 3 pages 821 833 year 1992 pmid 1602484 doi 10.1016 0022 2836 92 90403 7 ref ref name PUB00005265 cite journal author Driscoll PC, Campbell ID, Dudgeon TJ, Downing AK, Smith BO title The solution structure and backbone dynamics of the fibronectin type I and epidermal growth factor like pair of modules of tissue type plasminogen activator journal Structure volume 3 issue 8 pages 823 833 year 1995 pmid 7582899 doi 10.1016 S0969 2126 01 00217 9 ref . It consists of two antiparallel beta sheets, first a double stranded one, that is linked by a disulfide bond to a triple stranded beta sheet. The second conserved disulfide bridge links the C terminal adjacent strands of the domain. In human tissue plasminogen activator chain A the FN1 domain together with the following ... AJ title High resolution analysis of functional determinants on human tissue type plasminogen activator ...   more details



  1. Type I cytokine receptor

    Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokine s with four alpha helix helical strands. These receptors are also known under the name hemopoietin receptors , and share a common amino acid motif WSXWS in the extracellular portion adjacent to the cell membrane. Members of the type I cytokine receptor family comprise different chains, some of which are involved in ligand cytokine interaction and others that are involved in signal transduction . Signal transduction chains The signal transducing chains are often shared between different receptors within this receptor family. ref name isbn0 7216 0008 5 cite book author Lichtman, Andrew H. Abbas, Abul K. title Cellular and molecular immunology publisher Saunders location Philadelphia year 2003 edition 5th pages isbn 0 7216 0008 5 oclc doi ref The IL 2 receptor common gamma chain also known as CD132 is shared between IL 2 receptor IL 4 receptor IL 7 receptor IL 9 receptor IL 13 receptor IL 15 receptor ref name pmid7530740 cite journal author He YW, Adkins B, Furse RK, Malek TR title Expression and function of the gamma c subunit of the IL 2, IL 4, and IL 7 receptors. Distinct interaction of gamma c in the IL 4 receptor journal J. Immunol. volume 154 issue 4 pages 1596 605 year 1995 pmid 7530740 doi issn url http www.jimmunol.org cgi content abstract 154 4 1596 ref The common beta chain CD131 or CDw131 is shared between the following type I cytokine receptors GM CSF receptor IL 3 receptor IL 5 receptor . ref name pmid9422786 cite journal author Stomski FC, Woodcock JM, Zacharakis B, Bagley CJ, Sun Q, Lopez AF title Identification of a Cys motif in the common ... M receptor Examples Type I cytokine receptors include interleukin receptors, colony stimulating factor receptors and other cytokine receptors Interleukin receptors Type 1 interleukin receptors Colony ... receptors JAK STAT signaling pathway Category Cytokine receptors 1 Category Type I cytokine receptors ...   more details



  1. Type I topoisomerase

    Type I topoisomerases cut one strand of double stranded DNA, relax the strand, and reanneal the strands. They are further subdivided into two structurally and mechanistically distinct topoisomerases type IA and type IB. Type IA topoisomerases change the linking number of a circular DNA strand by units of strictly 1. Type IB topoisomerases change the linking number by multiples of 1 n . Historically, type IA topoisomerases are referred to as prokaryotic topo I, while type IB topoisomerases are referred to as eukaryotic topoisomerase. This distinction, however, no longer applies as type IA and type ... . Structure br Type IA topoisomerases have several domains, often number Domain 1 4. Domain I contains ... or strand of DNA is passed through. Domain III and I close and the DNA is re annealed. Type IB topoisomerases ... Main Anti Scl 70 antibodies Autoantibodies targeted against type I topoisomerase are called ... April 2011 ref References reflist External links MeshName DNA Topoisomerases, Type I www.rcsb.org ... functions. Prokaryotic topoisomerase I topo IA can only relax negative supercoiled DNA, whereas eukaryotic topoisomerase I topo IB can introduce positive supercoils, decatenate single stranded DNA, and relax DNA. Type IA topoisomerses Image TopoI.png thumb 400px Structure of topo III bound to single stranded DNA pdb ID 1I7D . Note that the DNA resembles B form DNA Introduction br Type IA topoisomerases ... with type IIA topoisomerases. They both form a 5 phosphotyrosine intermediate, and require a divalent metal ion to perform its work. Unlike type II topoisomerase type II topoisomerases , type IA topoisomerases ... II is a flexible bridge between domains III and IV. The structure of type IA topoisomerase resembles a lock, with Domains I, III and IV lie on the bottom of the structure ref Lima, Wang, and Mondragon ... about the DNA. Type IA topo variants br There are several variants of Type IA topoisomerases ... of this subclass include topo I, topo III which contain additional Zinc binding motifs , and reverse ...   more details



  1. Type-I superconductor

    Timeline of low temperature technology Type 1.5 superconductivity Type II superconductor Unconventional ... es Superconductor de tipo I ...   more details



  1. Type I tyrosinemia

    . Signs and symptoms Type 1 tyrosinemia typically presents in infancy as failure to thrive and hepatomegaly ... possible. Treatment The primary treatment for type 1 tyrosinemia is Nitisinone Orfadin . Nitisinone ... Typ I es Tirosinemia tipo 1 ...   more details




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