- Operon
Image operon.png thumb 350px right A typical operon In genetics , an operon is a functioning unit of genomic ... contained in the operon are either gene expression expressed together or not at all. Several genes must be both co transcribed and co regulated to define an operon. ref cite book last1 ... common than previously assumed. ref cite doi 10.1093 bfgp 3.3.199 ref History The term operon was first ... pmid 14406329 ref From this paper, the so called general theory of the operon was developed. This theory ... is considered a landmark event in the history of molecular biology. The first operon to be described was the lac operon in Escherichia coli E. coli . ref name Jacob1960 The 1965 Nobel Prize in Physiology ... concerning the operon and virus synthesis. Overview Operons occur primarily in prokaryote ... in a range of eukaryotes including chordate s. An operon is made up of several structural gene s arranged ... of a given operon, including repressor s, Corepressor genetics corepressor s, and Activator genetics activator s, are not necessarily coded for by that operon. The location and condition of the regulators ... to its authors, the term operon means to operate . ref cite pmid 21566161 ref As a unit of transcription An operon contains one or more structural gene s which are generally transcribed into one ... of an operon does not require the mRNA to be polycistronic, though in practice, it usually is. ref ... an operator . The operon may also contain regulatory gene s such as a repressor gene, which codes for a regulatory ... not be part of the operon itself, but may be located elsewhere in the genome. The repressor molecule ... 2011 Structure This is the general structure of an operon promoter biology Promoter a nucleotide ... defined in the lac operon as a segment between the promoter and the genes of the operon. ref name ... gene s the genes that are co regulated by the operon. Regulation Control of an operon is a type ... conditions. Operon regulation can be either negative or positive by induction or repression ... more details
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- Trp operon
Image Trpoperon.svg thumb 400px Structure of the trp operon. Trp operon is an operon a group of genes ... . The Trp operon is present in many bacteria , but was first characterized in Escherichia coli . It is regulated .... Discovered in 1953 by Jacques Monod and colleagues, the trp operon in E. coli was the first repressible operon to be discovered. While the lac operon can be activated by a chemical allolactose , the tryptophan Trp operon is inhibited by a chemical tryptophan . This operon contains five structural ... the transcription to be blocked. In the lac operon, allolactose binds to the repressor protein, allowing gene transcription, while in the trp operon, tryptophan binds to the repressor protein ... transcribing the genes in the operon. Also unlike the lac operon, the trp operon contains a leader peptide .... pg. 394 402 ref It is an example of negative regulation of gene expression. Within the operon s regulatory ... operon is produced upstream by the trpR gene, which is continually expressed at a low level ... the operon, so tryptophan is not produced from its precursor. When tryptophan is not present ... is not inhibited by the repressor. Attenuation Image Trp operon attenuation.svg thumb 400px Mechanism of transcriptional attenuation of the trp operon. Attenuator genetics Attenuation is a second mechanism of negative feedback in the trp operon. While the TrpR repressor decreases transcription by a factor ... the DNA sequence. This allows the process of translation to directly affect transcription of the operon. At the beginning of the transcribed genes of the trp operon is a sequence of 140 nucleotides ... of the operon will not occur. Part of the leader transcript codes for a short polypeptide of 14 amino ... anti termination hairpin. RNA polymerase is free to continue transcribing the entire operon. If tryptophan ... 4 structure which terminates transcription. The end result is that the operon will be transcribed ... genetics gene regulation lac operon Trp repressor Tryptophan Tryptophan operon leader External ... more details
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- Operon database
Orphan date April 2011 infobox biodatabase title ODB logo File Database.png description operon organizations scope organism center Ritsumeikan University laboratory College of Life Sciences author pmid Okuda & al. 2011 ref name pmid21051344 released 2009 standard format url http operondb.jp download webservice sql sparql webapp standalone license versioning frequency curation bookmark version ODB Operon DataBase is a database of conserved operon s in Genome sequencing sequenced genomes . ref name pmid21051344 cite journal quotes yes last Okuda first Shujiro authorlink coauthors Yoshizawa Akiyasu C year 2011 month Jan title ODB a database for operon organizations, 2011 update journal Nucleic Acids Res. volume 39 issue Database issue pages D552 5 publisher location England issn pmid 21051344 doi 10.1093 nar gkq1090 bibcode oclc id url pmc 3013687 language eng format accessdate laysummary laysource laydate quote ref See also Operon References references External links http operondb.jp Category Biological databases Category Gene expression Category Article Feedback 5 Biodatabase stub ... more details
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- Gal operon
lowercase The gal operon is a prokaryotic operon , which encodes enzymes necessary for galactose metabolism . ref name Wei93 cite journal author Weickert MJ, Adhya S title The galactose regulon of Escherichia coli journal Mol. Microbiol. volume 10 issue 2 pages 245 51 year 1993 month October pmid 7934815 doi 10.1111 j.1365 2958.1993.tb01950.x url ref The operon contains two operator genetics operators , O sub E sub for external and O sub I sub . The former is just before the promoter biology promoter , and the latter is just after the galE gene the first gene in the operon . Repression of gene expression works via binding of repressor molecules to the two operators. These repressors dimerize, creating a loop in the DNA. The loop as well as hindrance from the external operator prevent RNA polymerase from binding to the promoter, and thus prevent transcription genetics transcription . The gal operon of E. coli consists of 3 structural genes galE epimerase , galT galactose transferase , and galK galactokinase , which are transcribed from two overlapping promoters PG1 and PG2 upstream from galE . Regulation of the operon is complex since the GalE product, an epimerase that converts UDP glucose into UDP galactose, is required for the formation of UDP galactose for cell wall biosynthesis , in particlular the cell wall component lipopolysaccharide, even when cells are not using galactose as a carbon energy source. The gal operon is controlled by CRP cAMP as for the lac operon. ref name Wei93 ref cite journal author Sklar J, Weissman S, Musso RE, DiLauro R, de Crombrugghe B title Determination of the nucleotide sequence of part of the regulatory region for the galactose operon from Escherichia coli journal J. Biol. Chem. volume 252 issue 10 pages 3538 47 year 1977 month May pmid 193835 doi url http www.jbc.org cgi pmidlookup?view long&pmid 193835 ref CRP cAMP binds to 35 region .... citation needed date May 2011 See also lac operon References reflist Transcription Category Gene ... more details
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- Cps operon
multiple issues citation style November 2011 cleanup November 2011 context November 2011 one source November 2011 orphan December 2011 It is a regulatory system in Escherichia coli E.coli Producing different types of exopolysaccharide s. Exopolysacharides Protect bacteria from harsh environments, toxic chemicals or bacteriophage . Serve as matrices to link a number of different bacteria into a community or biofilm . Other bacterial exopolysaccharides cause health problems in humans regulation mechanism of Cps Operon Reduced levels of MDOs Membrane drived oligosaccharide s result in autophosphorilation of RcsC. The phosphate group transferred to RcsB. RcsB bind to RcsA. This complex act on the cps promotor and activates transcription of the cps gene. edit References Amani. A, Iran Category Escherichia coli ... more details
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- Lac operon
lowercase title Lac operon The lac operon is an operon required for the transport and metabolism of lactose ... gene s, lacZ, lacY and lacA. The lac operon is regulated by several factors including the availability of glucose and of lactose . Gene regulation of the lac operon was the first complex genetic regulatory ... regulation . Image lac operon1.png Layout of the lac operon. In its natural environment, the lac operon ... readily available energy source available such as glucose. The lac operon uses a two ... such diauxic growth patterns are known as xyl operon and ara operon ara operon , etc. Structure of the lac operon Image Lactose etc.png thumb 300px Structure of lactose and the products of its cleavage. The lac operon consists of three structural gene s, and a promoter biology promoter , a terminator .... The lac genes are organized into an operon that is, they are oriented in the same direction immediately ... all three genes lacZYA into mRNA. The DNA sequence of the E. coli lac operon , the lacZYA mRNA , and the lacI ... the lac operon and is always expressed constitutive . If lactose is missing from the growth medium, the repressor ... and release galactose and glucose. The diagram below summarizes these statements. Image Lac operon 2010 21 01.png thumb center 550px lac operon in detail Genetic nomenclature Three letter abbreviations ... operon. These compounds are mainly substituted galactosides, where the glucose moiety of lactose is replaced ... of the lac operon for physiological work. ref Stryer IPTG binds to repressor and inactivates ... ref Allolactose is an isomer of lactose and is the inducer of the lac operon. Lactose is galactose ... regulatory mutants of the lac operon, Jacob developed a system by which a second copy of the lac ... is a small protein which can diffuse in the cell. The copy of the lac operon adjacent to the defective ... affecting lacY and can only produce LacZ. In this version, only the copy of the lac operon that is adjacent ... dominant , it is dominant to wild type but affects only the copy of the operon which is immediately ... more details
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- Ars operon
operon that confers resistance to arsenicals and antimonials in Escherichia coli . It possesses ... dissociation of ArsD from the operon. However, as a homodimer it has four vicinal cysteine base pair ... l arsenical resistance operon trans acting repressor ArsD protein s. References reflist InterPro ... more details
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- L-arabinose operon
The small L small arabinose operon , also called ara operon , has genes encoding enzymes needed for the catabolism of arabinose to xylulose 5 phosphate , an intermediate of the pentose phosphate pathway . It has both positive regulation positive and negative regulation . The operon is found in Escherichia coli . It has been a focus for research in molecular biology for over since 1970, and has been investigated extensively at the Genetics genetic , biochemical , physiological , and biophysical levels. Structure The structural gene is araBAD . The regulator gene is araC . The genes, araBAD and araC , are transcribed in opposite directions. ref cite doi 10.1111 j.1574 6976.2010.00226.x ref The operators are araI and araO sub 2 sub . The operators lie between the AraC . AraI lies between the structural genes and the operator. The araI sub 1 sub and araI sub 2 sub are DNA binding sites that, when occupied by AraC, induce expression. Function Repression The ara operon is regulated by the AraC protein . If arabinose is absent, the dimer AraC protein represses the structural gene by binding to araI sub 1 sub and araO sub 2 sub and the DNA forms a loop. The loop prevents RNA polymerase from binding to the Promoter genetics promoter of the ara operon, thereby blocking Transcription genetics transcription . Activation When arabinose is present, arabinose binds AraC and prevents AraC from ... to bind to the promoter and transcribe the ara operon. Also for activation the binding of another ... on the presence of arabinose and cAMP. Sequence of the Operon araC araO araI araB araA araD See also The lac operon is another operon in E. coli that has been a focus for research in gene expression ... title Regulation of the small L small arabinose operon of Escherichia coli journal Trends in Genetics ... 02153 3 id accessdate author Schleif, R pmid 11102706 Category Gene expression de Ara Operon fr Op ron arabinose id Operon ara nl Arabinose operon ... more details
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- Threonine operon leader
Infobox rfam Name Threonine operon leader image RF00506.jpg width caption Predicted secondary structure and sequence conservation of Thr leader Symbol Thr leader AltSymbols Rfam RF00506 miRBase miRBase family RNA type Cis regulatory element Cis reg leader Tax domain Bacteria GO SO SO 0000233 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The threonine operon leader is an cis regulatory element RNA element . Threonine is one of at least 6 amino acid operon s are known to be regulated by Attenuator genetics attenuation . ref name kolter 1982 cite journal last Kolter first R coauthors Yanofsky C year 1982 title Attenuation in amino acid biosynthetic operons journal Annu Rev Genet volume 16 pages 113&ndash 134 pmid 6186194 doi 10.1146 annurev.ge.16.120182.000553 ref In each a leader sequence of 150 200 bp is found upstream of the first gene in the operon. This leader sequence can assume two different secondary structures known as the terminator and the anti terminator structure. In each case the leader also codes for very short peptide sequence that is rich in the end product amino acid of the operon. The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed. This structure forms when the cell has an excess of the regulatory amino acid and ribosome movement over the leader transcript is not impeded. ref name kolter 1982 When there is a deficiency of the charged tRNA of the regulatory amino acid the ribosome translating the leader peptide stalls and the antiterminator structure can form. This allows RNA polymerase to transcribe the operon. ref name kolter 1982 References reflist 1 External links Rfam id RF00506 name Threonine operon leader Category Cis regulatory RNA elements molecular cell biology stub ... more details
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- Tryptophan operon leader
Infobox rfam Name Tryptophan operon leader image RF00513.jpg width caption Predicted secondary structure and sequence conservation of Trp leader Symbol Trp leader AltSymbols Rfam RF00513 miRBase miRBase family RNA type Cis regulatory element Cis reg leader Tax domain Bacteria GO SO SO 0000233 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The Tryptophan operon leader is an cis regulatory element RNA element found at the 5 of some bacterial Trp operon tryptophan operons . The leader sequence can assume two different secondary structures known as the terminator and the anti terminator structure. The leader also codes for very short peptide sequence that is rich in Tryptophan. The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed. This structure forms when the cell has an excess of tryptophan and ribosome movement over the leader transcript is not impeded. ref cite journal last Kolter first R coauthors Yanofsky C year 1982 title Attenuation in amino acid biosynthetic operons journal Annu Rev Genet volume 16 pages 113 134 pmid 6186194 doi 10.1146 annurev.ge.16.120182.000553 ref When there is a deficiency of the charged tryptophanyl tRNA the ribosome translating the leader peptide stalls and the antiterminator structure can form. This allows RNA polymerase to transcribe the operon. At least 6 different amino acid operons are known to be regulated by this attenuation. References Reflist External links Rfam id RF00513 name Tryptophan operon leader Category Cis regulatory RNA elements molecular cell biology stub ... more details
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- Leucine operon leader
Infobox rfam Name Leucine operon leader image RF00512.jpg width caption Predicted secondary structure and sequence conservation of Leu leader Symbol Leu leader AltSymbols Rfam RF00512 miRBase miRBase family RNA type Cis regulatory element Cis reg leader Tax domain Bacteria GO SO SO 0000233 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The Leucine operon leader is an cis regulatory element RNA element found upstream of the first gene in the Leucine biosynthetic operon . ref name pmid6186194 cite journal author Kolter R, Yanofsky C title Attenuation in amino acid biosynthetic operons journal Annu. Rev. Genet. volume 16 issue pages 113 34 year 1982 pmid 6186194 doi 10.1146 annurev.ge.16.120182.000553 ref The leader sequence can assume two different secondary structures known as the terminator and the anti terminator structure. The leader also codes for very short peptide sequence that is rich in leucine amino acid. The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed. This structure forms when the cell has an excess of leucine and ribosome movement over the leader transcript is not impeded. ref name pmid6186194 When there is a deficiency of the charged leucyl tRNA the ribosome translation translating the leader peptide stalls and the antiterminator structure can form. This allows RNA polymerase to transcribe the operon. ref name pmid6186194 At least 6 amino acid operons are known to be regulated by attenuation. ref name pmid6186194 References reflist 1 External links Rfam id RF00512 name Leucine operon leader Category Cis regulatory RNA elements molecular cell biology stub ... more details
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- Histidine operon leader
Infobox rfam Name Histidine operon leader image RF00514.jpg width caption Predicted secondary structure and sequence conservation of His leader Symbol His leader AltSymbols Rfam RF00514 miRBase miRBase family RNA type Cis regulatory element Cis reg leader Tax domain Bacteria GO SO SO 0000233 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The Histidine operon leader is an cis regulatory element RNA element found in the bacteria l histidine operon . At least 6 amino acid operons are known to be regulated by Attenuator genetics attenuation . ref name pmid6186194 cite journal author Kolter R, Yanofsky C title Attenuation in amino acid biosynthetic operons journal Annu. Rev. Genet. volume 16 issue pages 113 34 year 1982 pmid 6186194 doi 10.1146 annurev.ge.16.120182.000553 ref In each a leader sequence of 150 200 bp is found upstream of the first gene in the operon. This leader sequence can assume two different secondary structures known as the terminator and the anti terminator structure. In each case the leader also codes for very short peptide sequence that is rich in the end product amino acid of the operon. The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed. This structure forms when the cell has an excess of the regulatory amino acid and ribosome movement over the leader transcript is not impeded. ref name pmid6186194 When there is a deficiency of the charged tRNA of the regulatory amino acid the ribosome translating the leader peptide stalls and the antiterminator structure can form. This allows RNA polymerase to transcribe the operon. ref name pmid6186194 References reflist 1 cite journal author Chan CL, Landick R title Dissection of the his leader pause site by base ... Chan CL, Landick R title The Salmonella typhimurium his operon leader region contains an RNA hairpin ... issn External links Rfam id RF00514 name Histidine operon leader Category Cis regulatory RNA elements ... more details
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- Alpha operon ribosome binding site
Infobox rfam Name Alpha operon ribosome binding site image RF00140.jpg width caption Predicted secondary structure and sequence conservation of Alpha RBS Symbol Alpha RBS AltSymbols Rfam RF00140 miRBase miRBase family RNA type Cis regulatory element Cis reg Tax domain Bacteria GO SO SO 0000233 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The alpha operon ribosome binding site in bacteria is surrounded by this complex pseudoknot ted RNA structure. Translation of the mRNA produces 4 ribosomal protein products, one of which S4 acts as a translational repressor by binding to the nested pseudoknot region. The mechanism of repression is thought to involve a conformational switch in the pseudoknot region and ribosome entrapment. ref cite journal last Schlax first PJ coauthors Xavier KA, Gluick TC, Draper DE year 2001 title Translational repression of the Escherichia coli alpha operon mRNA importance of an mRNA conformational switch and a ternary entrapment complex journal J Biol Chem volume 276 pages 38494&ndash 38501 pmid 11504736 doi 10.1074 jbc.M106934200 issue 42 ref References reflist 1 External links Rfam id RF00140 name Alpha operon ribosome binding site Category Cis regulatory RNA elements molecular cell biology stub ... more details
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- LACA
LACA may refer to lac operon Structure of the operon lacA , a structural gene in the lac operon. Luxembourg Approach Controllers Association , the air traffic control in Luxembourg. disambig ... more details
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- Operator (biology)
In genetics , an operator is a segment of DNA to which a transcription factor protein binds. It is classically defined in the lac operon lac operon as a segment between the promoter biology promoter and the genes of the operon . In the case of a repressor , the repressor protein physically obstructs the RNA polymerase from transcription genetics transcribing the genes . An inducer protein can displace a repressor protein from the operator site DNA , which results in an uninhibited operon . Category Regulatory sequences de Operator Genetik fa fr Op rateur biologie it Operatore biologia ja uk ... more details
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- AraC
AraC may refer to The araC gene and araC protein, components of the L arabinose operon in the genome of the bacterium Escherichia coli Cytarabine , a chemotherapy chemotherapeutic agent commonly used in the treatment of leukemia s and lymphoma s disambig ... more details
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- Polar effect (genetics)
For Polar effect in Chemistry Polar effect Unreferenced date November 2006 Polar effect in genetics occurs when the mutation of one gene prevents other genes in the same operon from being transcribed. Category Mutation Genetics stub ... more details
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- Modulon
For the spasmolytic Modulon Modulon drug Multiple issues unreferenced December 2009 context October 2009 An operon is a set of genes controlled by a single DNA binding protein. Multiple operons controlled by the same regulatory protein are grouped together as a regulon . A modulon is a regulon concerned with multiple pathways or functions, in which operons may be under individual controls as well as common, pleiotropic regulatory protein. For example, the CAP modulon contains all regulons operons, such as the lac operon and ara regulon, that are regulated by Catabolite Activator Protein CAP Cyclic adenosine monophosphate cAMP , but each operon has other regulators as well. Category Gene expression ... more details
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- Beta-galactoside permease
galactoside permease is a cell membrane membrane bound Membrane transport protein transport protein that active transport pumps lactose into the cell biology cell . See also lac operon permease galactoside External links MeshName Permease, beta galactoside Category Transport proteins enzyme stub ... more details
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- Inducer
operon The inducer in the lac operon lac operon is allolactose . ref name foster Slonczewski, Joan ... available in the system, the lac operon is repressed. This is because glucose actively prevents the induction of lacZYA . ref name foster ara operon In the ara operon ara operon , arabinose is the inducer ... more details
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- Stimulon
Unreferenced date November 2006 orphan date November 2009 In cell biology a stimulon is a collection of genes which may be in operon s and regulon s under regulation by the same stimulus. This term is generally used for prokaryote prokaryotic systems, for example quorum sensing in bacteria . Category Cell signaling Molecular cell biology stub ... more details
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- Attenuator (genetics)
species providing fast and sensitive regulation of gene operon s and is commonly used to repress ... sensing molecules the tryptophan biosynthetic operon has been found to use three different mechanisms ... operon the trp operon uses this mechanism in E. coli . RNA thermometers Temperature dependent ... in the trp operon of E. coli . ref name Yanofsky C. Yanofsky, Attenuation in the control of expression ... of the trp operon these mutants were not fully induced repressed by tryptophan . The total range of trp operon regulation is about 700 X on off . When the trp repressor was knocked out, one still ... operon was determined an unusual open reading frame ORF was seen immediately preceding the ORFs ... shown below was observed from the sequence of the trp operon. First, Yanofsky observed that the ORF ... the preemptor . The trp operon Image Trp operon attenuation.svg thumb 400px Mechanism of transcriptional attenuation of the trp operon. An example is the trp operon trp gene in bacteria . When there is a high ... operon gene sequence, contains four domains, where domain 3 can pair with domain 2 or domain ... of the trp operon. Since the protein coding genes are not transcribed due to rho independent ... that does not signal termination of transcription. Therefore the rest of the operon will be transcribed ... into a leader peptide, but is not part of the trp operon gene sequence. The attenuator allows more ... operon. While the TrpR repressor decreases transcription by a factor of 70, attenuation can ... of translation to directly affect transcription of the operon. At the beginning of the transcribed genes of the trp operon is a sequence of 140 nucleotides termed the leader transcript trpL . This transcript ... genes of the operon will not occur. Part of the leader transcript codes for a short polypeptide ... to continue transcribing the entire operon. If tryptophan levels in the cell are high, the ribosome ... result is that the operon will be transcribed only when tryptophan is unavailable for the ribosome ... more details
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- Activator (genetics)
A transcriptional activator is a protein that increases transcription genetics gene transcription of a gene or set of genes. Most activators are DNA binding proteins . Most activators function by binding sequence specifically to a DNA site located in or near a promoter genetics promoter and making protein protein interactions with the general transcription machinery RNA polymerase and general transcription factor s , thereby facilitating the binding of the general transcription machinery to the promoter. The DNA site bound by the activator is referred to as an activator site. The part of the activator that makes protein protein interactions with the general transcription machinery is referred to as an activating region. The part of the general transcription machinery that makes protein protein interactions with the activator is referred to as an activation target. Example The catabolite activator protein CAP also known as cAMP receptor protein , CRP activates transcription at the lac operon lac operon of the bacterium Escherichia coli . ref cite journal author Busby S., Richard H. Ebright Ebright RH. title Transcription activation by catabolite activator protein CAP journal J. Mol. Biol. volume 293 pages 199 213 year 2001 pmid 10550204 doi 10.1006 jmbi.1999.3161 ref Cyclic adenosine monophosphate cAMP is produced during glucose starvation, binds to CAP, causes a conformational change that allows CAP to bind to a DNA site located adjacent to the lac promoter. CAP then makes a direct protein protein interaction with RNA polymerase that recruits RNA polymerase to the lac promoter. Image Lac operon.png thumb center 550px lac operon in detail See also Promoter biology Repressor Operon Regulation of gene expression Transcription factor Glossary of gene expression terms References Reflist DEFAULTSORT Activator Genetics Category Gene expression Category Proteins de Aktivator Genetik fa pl Aktywator genetyka ru sv Aktivator genetik uk ... more details
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- Beta-galactoside transacetylase
Image gattrimerB IPTG.jpg thumb 310px GAT in complex with CoA and two molecules active site of IPTG viewed perpendicular to the molecular threefold axis of the enzyme galactoside transacetylase is an enzyme that transfers an acetyl group from acetyl CoA to galactoside s. Coded by the gene lacA in the lac operon of Escherichia coli . ref cite journal journal Structure year 2002 month April volume 10 issue 4 pages 581 8 title Structure of the lac operon galactoside acetyltransferase author Wang XG coauthors Olsen LR Roderick SL. pmid 11937062 doi 10.1016 S0969 2126 02 00741 4 ref Its precise function as part of the lac operon is not understood currently. ref cite journal journal C R Biol. year 2005 month June volume 328 issue 6 pages 568 75 title The lac operon galactoside acetyltransferase author Roderick SL. pmid 15950163 doi 10.1016 j.crvi.2005.03.005 ref The kinetics of the enzyme were worked out in 1995. ref cite journal author A. Lewendon coauthors J. Ellis, W.V. Shaw year 1995 title Structural and Mechanistic Studies of Galactoside Acetyltransferase, the Escherichia coli LacA Gene Product journal J. Biol. Chem. volume 270 pages 26326 31. pmid 7592843 doi 10.1074 jbc.270.44.26326 issue 44 ref See also transacetylase References references External links MeshName galactoside acetyltransferase EC number 2.3.1.18 Acyltransferases Category Transferases Category EC 2.3.1 transferase stub fr B ta galactoside transac tylase ... more details
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- Regulon
In cell biology and genetics , a regulon is a collection of genes or operon s under regulation by the same regulatory protein . This term is generally used for prokaryote prokaryotic systems, for example quorum sensing in bacteria . It is a group of operons genes spread around the chromosome but controlled by a common factor or stimulus. Multiple regulons can form a modulon . Category Cell biology de Regulon fr R gulon it Regulone pl Regulon pt Regulon ... more details
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