Infobox disease Name Osteomyelitis Image Ostermyelitis Tibia.jpg Caption Osteomyelitis of the tibia of a young ... MeshID D010019 Osteomyelitis osteo derived from the Greek word osteon , meaning bone, myelo meaning ... bone are the basis for distinguishing between Acute medicine acute osteomyelitis and wikt chronic chronic osteomyelitis . Osteomyelitis is an infective process that encompasses all of the bone wikt osseous ... medicine sclerosis and deformity. Chronic osteomyelitis may be due to the presence of intracellular ... of bacteria in osteomyelitis is likely an unrecognized contributing factor to its chronic form ... , the maxilla , and the mandibular bodies are especially susceptible to osteomyelitis. ref cite web url http www.emedicine.com emerg topic349.htm title Osteomyelitis accessdate 2007 11 11 author .... Acute osteomyelitis almost invariably occurs in children. When adults are affected, it may be because ... teeth, or other disease or drugs e.g., immunosuppressive therapy . Osteomyelitis is a secondary ... name Robbins In tubercular osteomyelitis, the long bones and vertebrae are the ones that tend to be affected ... forms of osteomyelitis. ref name Robbins Bloodstream sourced osteomyelitis is seen most frequently ... first P.J. coauthors L.M. Dickerson J.L. Sack title Diagnosis and management of osteomyelitis. journal ... infection. Staphylococcus aureus is the most common organism seen in osteomyelitis, seeded from ... than the exception. ref name carek Systemic mycotic fungal infections may also cause osteomyelitis. The two most common are Blastomyces dermatitidis and Coccidioides immitis . In osteomyelitis involving ... are due to tuberculosis spread hematogenously from the lung s . Tubercular osteomyelitis of the vertebral ... cepacia complex have been implicated in vertebral osteomyelitis in intravenous drug users. ref cite journal url http www.jidc.org issn1972 2680 current issue 59 vol 2 no 1 february 2008 152 cervical osteomyelitis caused by burkholderia cepacia after rhinoplasty title Cervical osteomyelitis caused by Burkholderia ... more details
The term osteomyelitis describes any new infection in the bone and bone marrow. Vertebral osteomyelitis ... Lori Dickerson, Jonathan Sack, M.D. title Diagnosis and Management of Osteomyelitis journal American ... afp 2001 0615 p2413.html accessdate March 27, 2012 ref Cases of vertebral osteomyelitis are so ... Miller first Janet title Vertebral Osteomyelitis url http www.mghradrounds.org clientuploads nov ... Encyclopedia Osteomyelitis year 2010 publisher United States National Library of Medicine location ... vertebral osteomyelitis is found in patients across a wide range of ages, the infection is commonly reported in young children and older adults. Vertebral osteomyelitis often attacks two vertebrae ... www.wheelessonline.com ortho vertebral osteomyelitis ref The prognosis for the disease is dependent ... approach is used to treat the disease. Other names for vertebral osteomyelitis include spinal osteomyelitis, spondylodiskitis, or disk space infection. ref name Zimmerli cite journal last Zimmerli, M.D. first Werner title Vertebral Osteomyelitis journal The New England Journal of Medicine date ... thumb Staphylococcus aureus, the most common microorganism associated with vertebral osteomyelitis File MRSA7820.jpg thumb MRSA, a rare pathogen associated with some cases of vertebral osteomyelitis ... common microorganism associated with vertebral osteomyelitis is the bacteria staphylococcus aureus ... strains. Streptococcus equisimilis may also be responsible for the onset of vertebral osteomyelitis ... osteomyelitis caused by Streptococcus dysgalactiae subsp. equisimilis journal The Journal of Medical ... onset in patients, and few symptoms characterize vertebral osteomyelitis. Correct diagnosis of the disease ... osteomyelitis include fever, swelling at the infection site, weakness of the vertebral column and surrounding ... position. ref name cedars cite web title Health Conditions Osteomyelitis url http www.cedars sinai.edu ... results in excruciating pain. In children, the presence of vertebral osteomyelitis can be signaled ... more details
Multiple issues copy edit October 2011 orphan October 2011 wikify November 2011 Xanthogranulomatous osteomyelitis XO is a peculiar aspect of osteomyelitis characterized by prevalent histiocytic infiltrate and foamy macrophage clustering. ref Rosai J 2004 . Rosai and Ackerman s Surgical Pathology. Philadelphia, Mosby, p. 2142. ref Clinical picture Five cases only have been reported so far, involving rib, tibial epiphysis, ulna, distal tibia and femur. Young individuals are prevalently affected but one case was described in a 50 year old woman. Pain, swelling of possibly long duration, fever and increased Erythrocyte sedimentation rate ESR are some of the main clinical findings. X ray examination shows lytic foci with sclerotic margins. ref name Cozzutto Cozzutto C 1984 Xanthogranulomatous osteomyelitis. Arch Pathol Lab Med 108 973 976. ref ref name Vankalakunti Vankalakunti M, Saikia UN, Mathew M, Kang M 2007 . Xanthogranulomatous osteomyelitis of ulna mimicking a neoplasm. World J Surg Oncol 5 46 1 4. ref ref name Kashani Kashani MM, Zakerian BZ, Shayan K, Riyasi F 2010 . Xanthogranulomatous osteomyelitis of femur. Iran J Orthop Surg 8 4 187 190. ref ref name Kamat Kamat G, Gramapuroit V, Shettar C, Myageri A 2011 . Xanthogranulomatous osteomyelitis presenting as swelling in right tibia. Case report. Case Rep Pathol, in press. ref A neoplastic process can be suspected. Pathology The granulomatous tissue largely comprises foam cells of monocyte macrophage origin positive for KP1, HAM56, CD11b and CD68. Neutrophils, hemorrhagic foci and numerous plasma cells are additional findings. ref name Cozzutto ref name Vankalakunti ref name Kashani ref name Kamat Staphylococcus aureus was isolated in the case reported by Kamat et al. ref name Kamat A delayed type hypersensitivity reaction in cell mediated immunity has been suggested in this type of infiltrate that is composed of macrophages and T cells. ref name Vankalakunti T cells are represented by a mixture of CD4 and CD8 ... more details
Garre s sclerosing osteomyelitis is a type of chronic osteomyelitis . It is a rare disease . ref name pmid12457091 It mainly affects children and young adults. ref name pmid17921638 It is associated with dental caries cavities in the teeth . ref name pmid17921638 A repaired or repairing osteomyelitis in which the repair process wins , and collagen and bone matrix are successfully deposited. Clarify date February 2011 References Reflist refs ref name pmid12457091 cite journal author Belli E, Matteini C, Andreano T title Sclerosing osteomyelitis of Garr periostitis ossificans journal J Craniofac Surg volume 13 issue 6 pages 765 8 year 2002 month November pmid 12457091 doi url ref ref name pmid17921638 cite journal author Suma R, Vinay C, Shashikanth MC, Subba Reddy VV title Garre s sclerosing osteomyelitis journal J Indian Soc Pedod Prev Dent volume 25 Suppl issue pages S30 3 year 2007 pmid 17921638 doi url ref Diseases of the musculoskeletal system and connective tissue DEFAULTSORT Garre s Sclerosing Osteomyelitis Category Bacterial diseases Category Skeletal disorders Disease stub ... more details
Infobox disease Name Chronic recurrent multifocal osteomyelitis Image Alt Caption DiseasesDB 34523 ICD10 ... GeneReviewsName Chronic recurrent multifocal osteomyelitis CRMO multifocal because it can erupt in different sites, primarily bones osteomyelitis because it is very similar to that disease but appears to be without any infection , also known as chronic recurring multifocal osteomyelitis , is a rare ... similar to osteomyelitis , but without the infection. Some doctors thought CRMO was related ... form of chronic recurrent multifocal osteomyelitis known as Majeed syndrome , while mutations ... homolog of pstpip2, PSTPIP2, in the etiology of chronic recurrent multifocal osteomyelitis are uncertain ... last1 El Shanti first1 HI last2 Ferguson first2 PJ title Chronic recurrent multifocal osteomyelitis ... osteomyelitis , ewing sarcoma , leukemia , lymphoma , rhabdomyosarcoma , neuroblastoma metastasis ... Wirksamkeit im Einsatz bei der chronischen rekurrierenden multifokalen Osteomyelitis? Eine ... last2 Singh first2 VA title Chronic recurrent multifocal osteomyelitis of the first metatarsal bone ... osteomyelitis. In addition, bone marrow aspiration demonstrated significant dyserythropoiesis defective ... Congenital dyserythropoietic anemia and chronic recurrent multifocal osteomyelitis, uncommon ... also had Sweet syndrome . The association of Sweet syndrome with chronic recurrent multifocal osteomyelitis ... Congenital dyserythropoietic anemia and chronic recurrent multifocal osteomyelitis in three related ... Brown, Robert Wilkinson, Timothy title Chronic recurrent multifocal osteomyelitis journal Radiology ..., Stiehm ER title Treatment of chronic recurrent multifocal osteomyelitis CRMO with interferon gamma ... recurrent multifocal osteomyelitis, chronic dyserythropoietic anemia, and transient inflammatory ... osteomyelitis Office of Rare Diseases 10088 Majeed syndrome Diseases of the musculoskeletal system and connective tissue DEFAULTSORT Chronic Recurrent Multifocal Osteomyelitis Category Bacterial diseases ... more details
Unreferenced stub auto yes date December 2009 Involucrum is a layer of new bone growth outside existing bone seen in pyogenic osteomyelitis . It results from the stripping off of the periosteum by the accumulation of pus within the bone, and new bone growing from the periosteum . It can be seen radiography radiographically e.g. with x ray s , but is extremely rare in developed countries as osteomyelitis is rarely left untreated. See also Sequestrum Osteochondropathy Category Skeletal system Musculoskeletal stub ... more details
italic title Mycobacterium arosiense is a species of Mycobacterium . ref Cite pmid 19386835 ref It can cause osteomyelitis . ref cite pmid 18842863 ref References reflist Mycobacteria Category Corynebacterineae Mycobacterium stub ... more details
Infobox Disease Name Infectious bone disease Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D001850 A infectious bone disease is a bone disease primarily associated with an infection. An example is osteomyelitis . Osteochondropathy disease stub Category Osteopathies ... more details
CRMO may refer to 41xx steel , also known CrMo CHOU AM , radio station also known as CRMO Radio Moyen Orient Chief risk officer CRO , also known as Chief risk management officer CRMO Chronic recurrent multifocal osteomyelitis disambiguation ... more details
Majeed syndrome is an inherited skin disorder characterized by chronic multifocal osteomyelitis, congenital dyserythropoietic anemia and a neutrophilic dermatosis. ref name Bolognia cite book author Rapini, Ronald P. Bolognia, Jean L. Jorizzo, Joseph L. title Dermatology 2 Volume Set publisher Mosby location St. Louis year 2007 pages isbn 1 4160 2999 0 oclc doi accessdate ref See also TNF receptor associated periodic syndrome List of cutaneous conditions References reflist Dermatology stub Category Autoinflammatory syndromes ... more details
File Potts puffy tumor 004.jpg thumb Pott s puffy tumor, spreading towards patients brain. MRI, T1, sagittal, gadolinium contrast. Pott s puffy tumor , first described by Sir Percivall Pott in 1760,Pott s Puffy tumor is a rare clinical entity characterized by subperiosteal abscess associated with osteomyelitis. is characterized by an osteomyelitis of the frontal bone, either direct or through haematogenic spread. This results in a swelling on the forehead, hence the name. The infection can also spread inwards, leading to an intracranial abscess .Pott s Puffy tumor can be associated with cortical vein thrombosis, epidural abscess, subdural empyema, and brain abscess. The cause of vein thrombosis is explained by venous derange of the frontal sinus, which occurs through diplopic veins, which communicate with the dural venous plexus septic thrombi can potentially evolve from foci within the frontal sinus and propagate through this venous system.This type of chronic osteomyelitis of the frontal bone is confused with acute sub periosteal abscess of the frontal bone, which presents as a discrete collection over the frontal sinus. Although it can affect all ages, it is mostly found among teenagers and adolescent s.It is usually seen as a complication of frontal sinusitis or trauma predominantly in the adolescent age group. Etiology Frontal sinusitis most common A trauma may be present in the history Intranasal cocaine methamphetamine abuse ref cite journal author Banooni P, Rickman LS, Ward DM title Pott puffy tumor associated with intranasal methamphetamine journal JAMA volume 283 issue 10 pages 1293 year 2000 month March pmid 10714727 doi ref Craniotomy rare Treatment Treatment generally consists of surgical drainage, and long term 6 to 8 weeks use of antibiotics. References references http www.ncbi.nlm.nih.gov pubmed 19098585 Category Skeletal disorders pl Guz Potta ... more details
Unreferenced stub auto yes date December 2009 A sequestrum is a piece of dead bone that has become separated during the process of necrosis from normal sound bone. It is a complication sequela of osteomyelitis . The pathological process is as follows infection in the bone leads to an increase in intramedullary pressure due to inflammatory exudates the periosteum becomes stripped from the osteum, leading to vascular thrombosis bone necrosis follows due to lack of blood supply sequestra are formed Image Bony sequestrum in a child femur.jpg thumb right An X ray of a child s femur showing a bony sequestrum highlighted by the blue arrow. The sequestra are surrounded by sclerotic bone which is relatively avascular without a blood supply . Within the bone itself, the haversian canals become blocked with scar tissue, and the bone becomes surrounded by thickened periosteum. Due to the avascular nature of this bone, antibiotics which travel to sites of infection via the bloodstream poorly penetrate these tissues. Hence the difficulty in treating chronic osteomyelitis. At the same time as this, new bone is forming known as involucrum . Opening in this involucrum allow debris and exudates including pus to pass from the sequestrum via sinus tracts to the skin. Rarely, a sequestrum may turn out to be an osteoid osteoma, a rare tumor of the bone. Osteochondropathy Category Bone fractures Category Gross pathology Pathology stub de Sequester Medizin ... more details
Disorders of the skin Athlete s foot Callus and Corns of the Skin Ingrown nail Onychocryptosis Ingrown Toenail Keratosis Keratosis palmaris et plantaris Disorders of the joints Hallux valgus bunion Hallux varus Diabetic Arthropathy Neuropathic joint disease Charcot Foot Rheumatoid arthritis Osteoarthritis Disorders of the bones Fracture bone Fracture Jones Fracture Dupuytren fracture or Pott s fracture Osteomyelitis Disorders of the nerves Tarsal tunnel syndrome Neuroma Metatarsalgia Nerve entrapment Combined disorders Pes cavus Cavus foot Club foot Genetic disorders Polydactyly Specific manifestations of systemic disease Diabetic foot Rheumatoid arthritis Rheumatoid foot Neuropathy Plantar fasciitis Category Medical lists Foot and ankle disorders ... more details
From MoS DAB use ONE LINK per entry, SHORT descriptions. AVOID piping, external links, redlinks with little potential Garre may refer to Garre , a Somali pastoralist clan that live in Somalia, Kenya, and Ethiopia Nilda Garr born 1945 , a former leftist militant and the current defense minister of Argentina Oscar Garr born 1956 , a former Argentine football defender Carl Garr 1857 1928 , Swiss surgeon who discovered staphylococcus, Garr s disease and Garr s osteomyelitis See also Garr Gar disambiguation disambig de Garre ... more details
italic title Taxobox name Mycobacterium nonchromogenicum regnum Bacteria phylum Actinobacteria ordo Actinomycetales subordo Corynebacterineae familia Mycobacterium Mycobacteriaceae genus Mycobacterium species M. nonchromogenicum binomial Mycobacterium nonchromogenicum binomial authority Mycobacterium nonchromogenicum is a species of Mycobacterium . ref cite journal pmid 17366041 doi 10.1080 00365540600798817 volume 39 issue 2 title Infectious tenosynovitis and osteomyelitis caused by Mycobacterium nonchromogenicum year 2007 journal Scand. J. Infect. Dis. pages 179 80 last1 N rgaard Eskesen first1 Arne last2 Skr mm first2 Inge last3 Steinbakk first3 Martin ref References reflist Mycobacteria Category Acid fast bacilli Category Corynebacterineae Category Nontuberculous mycobacteria Mycobacterium stub ... more details
Infobox disease Name Brodie abscess Image Caption DiseasesDB ICD10 ICD10 M 86 8 m 86 ICD9 ICD9 730.1 ICDO OMIM MedlinePlus eMedicineSubj article eMedicineTopic 1248682 MeshID A Brodie abscess is a subacute osteomyelitis , which may persist for years before converting to a frank osteomyelitis. Classically, this may present after conversion as a draining abscess extending from the tibia out through the shin. Most frequent causative organism is Staphylococcus aureus. Clinical Presentation Localized pain, often nocturnal, alleviated by aspirin. Often mimics the symptoms of Osteoid osteoma , which is typically 1 cm diameter. Most Frequent Sites Usually occurs at the metaphysis of long bones. Distal tibia, proximal tibia, distal femur, proximal or distal fibula, and distal radius. Radiographic Features Oval, elliptical, or serpiginous radiolucency usually 1 cm surrounded by a heavily reactive sclerosis, granulation tissue, and a nidus often less than 1 cm. The margins often appear scalloped on radiograph. Brodie s abscess is best visualized using Computed tomography CT scan. Associated atrophy of soft tissue near the site of infection and shortening of the affected bone. Osteoblastoma may be a classic sign for Brodie s abscess. History Brodie abscess is named after Sir Benjamin Collins Brodie, 1st Baronet Treatment Mainly surgical approach has to be taken. If cavity is small then surgical evacuation & curettage is performed under antibiotic cover. If cavity is large then after evacuation, packing with cancellous bone chips External links http www.whonamedit.com synd.cfm 961.html Whonamedit Osteochondropathy Category Bacterial diseases Category Osteopathies pl Ropie Brodiego ... more details
italic title Refimprove date February 2012 Taxobox name Mycobacterium goodii regnum Bacteria phylum Actinobacteria ordo Actinomycetales subordo Corynebacterineae familia Mycobacterium Mycobacteriaceae genus Mycobacterium species M. goodii binomial Mycobacterium goodii binomial authority Brown et al. 1999, ATCC 700504 Mycobacterium goodii is an acid fast bacterium bacterial species in the phylum Actinobacteria and the genus Mycobacterium . ref name autogenerated1 Brown et al. 1999. Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections a cooperative study from the International Working Group on Mycobacterial Taxonomy. Int. J. Syst. Bacteriol., 1999, 49, 1493 1511. ref Description M. goodii cells are Gram stain Gram positive , nonmotile, acid fast rods. Colony characteristics Colonies of M. goodii are smooth to mucoid, off white to cream coloured. in After 10 14 days incubation, 78 of all strains produce a yellow or orange pigment. Citation needed date February 2012 Physiology Strains of M. goodii show rapid growth on Middlebrook 7H10 and trypticase soy agar at 30 C, 35 C and 45 C within 2 4 days. They are susceptible to the antibiotics amikacin , ethambutol , and sulfamethoxazole but show intermediate susceptibility to ciprofloxacin , doxycycline and tobramycin and variable susceptibility to cefmetazole , cefoxitin and clarithromycin . They are resistant to isoniazid and rifampicin . Pathogenesis M. goodii is found in many of the same settings as M. smegmatis and members of the M. fortuitum complex. It can cause post traumatic wound infections especially those following open fractures and with associated osteomyelitis and chronic lipoid pneumonia . Type strain The type strain of M. goodii Strain MO69 ATCC 700504 CIP 106349 DSM 44492 JCM 12689 was first isolated from a patient with a post traumatic osteomyelitis of the heel in the United States. r ... more details
italic title Taxobox name Mycobacterium lentiflavum regnum Bacteria phylum Actinobacteria ordo Actinomycetales subordo Corynebacterineae familia Mycobacterium Mycobacteriaceae genus Mycobacterium species M. lentiflavum binomial Mycobacterium lentiflavum binomial authority Springer et al. 1996, ATCC 51985 Mycobacterium lentiflavum br Etymology Lentus from Latin for slow, flavus , Latin for yellow. Description Gram positive , nonmotile and acid fast coccobacilli . Colony characteristics Smooth colonies, with bright yellow pigmentation 1 2mm in diameter. Physiology Slow growth on L wenstein Jensen medium at temperatures between 22 C and 37 C within 3 4 weeks. Generally resistant to isoniazid , rifampin , ethambutol and streptomycin . Differential characteristics Phylogenetic analysis, based on an evaluation of 16S rDNA sequences, places M. lentiflavum in an intermediate position between rapidly and slowly growing mycobacteria , closely related to Mycobacterium simiae and Mycobacterium genavense . Pathogenesis In young children with cervical lymphadenitis and in immunocompromised patients ref Molteni C, Gazzola L, Cesari M, Lombardi A, Salerno F, Tortoli E, et al. http www.cdc.gov ncidod EID vol11no01 04 0523.htm Mycobacterium lentiflavum infection in immunocompetent patient. Emerg Infect Dis . 2005 Jan. ref One case of verterbral osteomyelitis reported Biosafety level 2 Type strain First isolated from a patient with spondylodiscitis verterbral osteomyelitis . Further isolates from clinical specimens were obtained due to the use of contaminated bronchoscopes . Also recovered from gastric juice , sputum and urine samples. Strain 2186 92 ATCC 51985 CCUG 42422 CCUG 42559 CIP 105465 DSM 44418 JCM 13390. References reflist Springer et al. 1996. Isolation and characterization of a unique group of slowly growing mycobacteria description of Mycobacterium lentiflavum sp. nov. J. Clin. Microbiol. 34, 1100 1107. Mycobacteria DEFAULTSORT Mycobacterium Lentiflavum Category Acid fast ... more details
italic title Taxobox name Staphylococcus pettenkoferi regnum Bacteria phylum Firmicutes classis Bacilli ordo Bacillales familia Staphylococcaceae genus Staphylococcus species Staphylococcus pettenkoferi Staphylococcus pettenkoferi honouring Max von Pettenkofer , 1818 1901, German pioneer in the field of hygiene and public health was described in 2007 and is a member of the bacterial genus Staphylococcus , consisting of spherical, Gram positive , non motile, non spore forming, facultative anaerobic bacteria . It is coagulase negative and is probably a commensal organism on the skin of humans. Description Colonies are 1 2 mm in diameter, sometimes showing yellow pigmentation when grown at Room temperature ambient temperature . Clinical Like other coagulase negative staphylococci, S. pettenkoferi only rarely causes disease, but may occasionally cause infection in patients whose immune system is compromised. Most S. pettenkoferi strains have been isolated from the skin or from blood culture s of patients in Germany and Belgium. Recently S. pettenkoferi was identified as the cause of osteomyelitis in a diabetic foot infection in France. References Tr lzsch K, Grabein B, Schumann P, Mellmann A, Antonenka U, Heesemann J, Becker K. Staphylococcus pettenkoferi sp. nov., a novel coagulase negative staphylococcal species isolated from human clinical specimens. Int. J. Syst. Evol. Microbiol. 2007 57 1543 8. Lo ez C, Wallet F, Pischedda P, Renaux E, Senneville E, Mehdi N, Courcol RJ. First case of osteomyelitis caused by Staphylococcus pettenkoferi . J. Clin. Microbiol. 2007 45 1069 71 Category Staphylococcaceae Category Gram positive bacteria Category Article Feedback 5 bacteria stub ... more details
Walter H. Burkholder was an American plant pathologist who helped establish the role of bacteria as plant pathogens. He was awarded a Ph.D. by Cornell University in 1917 and subsequently appointed as professor of plant pathology. In 1950 he first described the bacteria, Pseudomonas cepacia , later Burkholderia spp., responsible for causing sour skin disease in onions and colonising the Rhizosphere ecology rhizosphere of many plant species. Bacterial strains from the Burkholderia cepacia complex Bcc are opportunistic pathogens in humans with cystic fibrosis and have been implicated in vertebral osteomyelitis in intravenous drug abusers. ref http www.jidc.org issn1972 2680 current issue 59 vol 2 no 1 february 2008 152 cervical osteomyelitis caused by burkholderia cepacia after rhinoplasty Journal of Infection in Developing Countries ref This complex of at least 9 closely related species or genomovar s is currently the focus of research because of their remarkable variability as plant and human pathogens, saprophytes , and biocontrol and bioremediation agents. ref http www.apsnet.org education feature BurkholderiaCepacia Burkholderia cepacia Friend or Foe? Jennifer L. Parke ref Burkholder was a member of the Society of American Bacteriologists References reflist External links http arjournals.annualreviews.org doi abs 10.1146 annurev.mi.02.100148.002133 Annual Review of Microbiology http arjournals.annualreviews.org doi abs 10.1146 annurev.py.22.090184.001125 Annual Review of Phytopathology http findarticles.com p articles mi m1200 is 16 172 ai n21079947 Some bacteria can cross the line Science News, Oct 20, 2007 Susan Milius http findarticles.com p articles mi m1200 is 1998 Nov 7 ai 53280910 Is natural pesticide too hard on people? Science News, Nov 7, 1998 S. Milius Bibliography Diseases and Insect and other Pests of the Field Bean in New York Cornell Extension Bulletin. no. 58. Walter H. Burkholder, Cyrus Richard Crosby Persondata Metadata see Wikipedia Persondata . ... more details
Orphan date September 2010 Taksta previously CEM 102 is a front loaded oral dosing regimen of sodium fusidate under development in the U.S. as an antibiotic for gram positive infections including drug resistant strains such as methicillin resistant Staphylococcus aureus MRSA . ref Cite web url http www.earthtimes.org articles show cempra announces expansion of clinical,1234560.shtml title Cempra Announces Expansion of Clinical Management Team to Advance Leading Antibacterial Clinical Programs TAKSTA TM and CEM 101 ref Clinical trials Jan 2010 Taksta has completed enrollment in a Phase 2 trial due to run until March 2010 and is preparing for Phase 3 studies in the U.S. for acute bacterial Skin and skin structure infection skin structure infection s being compared with Linezolid . ref Cite web url http www.pharmaceutical business review.com news cempra completes enrollment in phase 2 taksta trial 100119 title Cempra Completes Enrollment In Phase 2 Taksta Trial date Jan 2010 ref ref Cite web url http clinicaltrials.gov ct2 show NCT00948142 title Safety and Efficacy of CEM 102 Compared to Linezolid in Acute Bacterial Skin Infections ref Sep 2010 Taksta demonstrated comparable clinical success rates compared to linezolid in a Phase 2 trial in the U.S. for acute bacterial skin and skin structure infections. ref Craft JC, Moriarty SR, Clark K, Scott D, Degenhardt TP, Still JG, Corey GR, Still JG, Das A, Fernandes P 2011 . A randomized, double blind Phase 2 study comparing the efficacy and safeety of an oral fusidic acid loading dose regimen to oral linezolid in the treatment of acute bacterial skin and skin structure infections. Clinical Infectious Diseases 52 Supplement 7 S520 S226. ref Jun 2011 Taksta may be effective in the treatment of chronic prosthetic joint infections and osteomyelitis. ref Wolfe CR. 2011 Case report treatment of chronic osteomyelitis. Clinical Infectious Diseases 52 Supplement 7 S538 S541. ref See also Fusidic acid , licensed outside the US and is ... more details
Wiktionary Caries is a progressive destruction of any kind of bone structure, including the Human skull skull , rib s and other bones, or the tooth teeth . Caries can be caused by osteomyelitis , which is a microorganism disease . A disease that involves caries is mastoiditis , an inflammation of the mastoid process , in which the bone gets eroded. Types Dental caries sing. is one of many types of caries. Dental caries affects different parts of the teeth enamel, dentin, or cementum in the crown or the root of the tooth. Nearly all cases contain bacteria such as Streptococcus mutans and Lactobacillus , which produce lactic acid as the products responsible for the caries. ref name Ullmanns Wolfgang Weinert in Oral Hygiene Products Ullmann s Encyclopedia of Industrial Chemistry, 2005, Wiley VCH, Weinheim DOI 10.1002 14356007.a18 209 ref References references Category Gross pathology Category Bacterial diseases Category Skeletal system id Karies ja uk de Zahnkaries ... more details
italic title Taxobox name Acremonium strictum regnum Fungi phylum Ascomycota classis Sordariomycetes subclassis Hypocreomycetidae ordo Hypocreales familia Incertae sedis genus Acremonium species A. strictum binomial Acremonium strictum binomial authority W. Gams, 1971 synonyms Cephalosporium acremonium Corda, 1839 small br Haplotrichum acremonium Corda Pound & Clem., 1896 small br Hyalopus acremonium Corda M.A.J. Barbosa, 1941 small Acremonium strictum is a plant, animal, and human pathogen . The genus Acremonium contains around 100 species, most of which are saprophytic, being isolated from dead plant material and soil. Some species cause disease in man and animals, causing Eumycetoma mycetoma , onychomycosis , and hyalohyphomycosis . Clinical manifestations of hyalohyphomycosis caused by Acremonium include arthritis , osteomyelitis , peritonitis , endocarditis , pneumonia , cerebritis and soft tissue infection. DEFAULTSORT Acremonium Strictum Category Plant pathogens and diseases Category Hypocreales Hypocreales stub plant disease stub ... more details
Carl Alois Philipp Garr 12 December 1857, Bad Ragaz Ragaz 6 March 1928 ref http cancerweb.ncl.ac.uk cgi bin omd?Garre, Carl Definition Garre, Carl from Online Medical Dictionary bot generated title at cancerweb.ncl.ac.uk ref ref http cpr.uni rostock.de metadata cpr professor 000000002908 Catalogus Professorum Rostocheinsium University of Rostock ref was a Swiss surgeon . He proved that Staphylococcus aureus causes carbuncle s and boil s by experimenting on himself ref cite book last de Kruif first Paul title The Microbe Hunters publisher Pocket Books location New York year 1959 month August chapter Koch The Death Fighter chapterurl http www.cc.gatech.edu grads h Idris.Hsi Stories The Microbe Hunters.htm quote Another pupil of Koch was the now forgotten hero, Dr. Garr of Basel, who gravely rubbed whole test tubes full of another kind of microbe which Pasteur had alleged was the cause of boils into his own arm. Garr came down horribly with an enormous carbuncle and twenty boils the tremendous dose of microbes he shot into himself might easily have finished him but he dismissed his danger as merely unpleasant and shouted triumphantly I know that this microbe, this staphylococcus, is the true cause of boils and carbuncles pages pg 132 ref and had one condition named after himself, Garr s disease ref http www.biology online.org dictionary Garres disease Garres disease definition from Biology Online.org bot generated title at www.biology online.org ref ref cite book last Sebastian first Anton authorlink Anton Sebastian title A Dictionary of the History of Medicine publisher Parthenon location Carnforth year 1999 isbn 1850700214 pages pg 335 url http books.google.com ?id f70MZLHwvp0C&pg PA335&lpg PA335&dq Carl Garr C3 A9 ref Garre s sclerosing osteomyelitis sclerosing osteitis form of chronic osteomyelitis with proliferative periostitis ref http cancerweb.ncl.ac.uk cgi bin omd?Garre 27s osteomyelitis Definition Garre s osteomyelitis from Online Medical Dictionary bot g ... more details
Infobox Disease Name PAGENAME Caption DiseasesDB ICD10 ICD9 ICDO OMIM 612852 MedlinePlus eMedicineSubj eMedicineTopic MeshID Deficiency of the interleukin 1 receptor antagonist DIRA is a rare disease rare , autosomal recessive , genetic disorder genetic autoinflammatory syndrome resulting from mutation s in IL1RN , the gene encoding the interleukin 1 receptor antagonist . The mutations result in an abnormal protein that is not secreted, exposing the cells to unopposed interleukin 1 activity. This results in sterilization microbiology sterile multifocal osteomyelitis bone inflammation in multiple places , periostitis inflammation of the membrane surrounding the bones , and pustulosis due to skin inflammation from birth. References Aksentijevich I, Masters SL, Ferguson PJ et al. . http content.nejm.org cgi content short 360 23 2426 An Autoinflammatory Disease with Deficiency of the Interleukin 1 Receptor Antagonist . N Engl J Med . 2009 360 2426 2437. See also Neonatal onset multisystem inflammatory disease NOMID Category Autoinflammatory syndromes Category Rare diseases disease stub ... more details
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