Infobox disease Name Osteosarcoma Image Osteosarcoma intermed mag.jpg Caption Intermediate magnification micrograph of an osteosarcoma center and right of image adjacent to non malignant bone left bottom ... radio 504 eMedicine2 radio 505 MeshID D012516 Osteosarcoma is an aggressive malignant neoplasm ...., Jaffe N. title The epidemiology of osteosarcoma. In Jaffe N. et al. Pediatric and Adolescent Osteosarcoma ... 978 1 4419 0284 9 1 ref Incidence Osteosarcoma is the eighth most common form of childhood cancer ... cancers. ref name OttavianiJaffe Incidence rates for osteosarcoma in U.S. patients under 20 years ... gene is associated with a high risk of osteosarcoma development. 2. Bone dysplasias, including ... the risk of osteosarcoma. 3. Li Fraumeni syndrome germline TP53 mutation is a predisposing factor for osteosarcoma ... bloc resection is the treatment of choice in osteosarcoma. ref name OttavianiJaffe Although about 90 ... cancer deaths. Mortality rates due to osteosarcoma have been declining at approximately 1.3 per year. Long term survival probabilities for osteosarcoma have improved dramatically during the late ... thumb 120px left Predilections of osteosarcoma The tumor may be localized at the end of the long bone. Most often it affects the upper end of tibia or humerus , or lower end of femur . Osteosarcoma ... Osteosarcoma very high mag.jpg thumb right High magnification micrograph showing osteoid formation in an osteosarcoma, H&E stain Microscopically The characteristic feature of osteosarcoma is presence ... url ref Causes The causes of osteosarcoma are not known. Several research groups are investigating ... 12 26 year 2009 pmid 19149759 doi 10.2174 157488709787047585 ref The connection between osteosarcoma ... association between water fluoridation and deaths due to osteosarcoma. One study showed 6.9 times the occurrence of osteosarcoma in fluoridated communities compared to non fluoridated areas. ref ... RJ. Radiation induced periosteal osteosarcoma. Grand Rounds 10 13 18 http www.grandrounds e med.com ... more details
The most common bone tumor is called osteosarcoma , which usually affects older dogs or giant breed dogs. Osteosarcoma seems to be rare in cats. Osteosarcoma is an aggressive cancer that can develop in any bone of the body but the majority is seen in the limbs eg elbow or the knee . Signs and symptoms Dogs with limb osteosarcoma typically show lameness and swelling at the affected site. For other sites, dogs may show difficulty to open their mouth if jaw bone cancer , nasal discharge if nasal cavity bone cancer or neurological signs if spine bone cancer . Diagnosis The initial evaluation involves X rays of the affected site, but the only way to confirm the diagnosis is by tissue biopsy . ref name MacEwan 2001 cite book author Withrow SJ, MacEwen EG, eds title Small Animal Clinical Oncology edition 3rd ed. publisher W.B. Saunders Company year 2001 ref Treatment Depending on the pet s unique condition, there are several treatment options, including surgery, chemotherapy and radiation therapy . References Reflist External links http www.petcancercenter.org Cancer Types Bone.html Bone Cancer in Cats and Dogs from Pet Cancer Center http www.vet.uga.edu vpp clerk Kramer index.php Canine osteosarcoma from UGA Veterinary School of Medicine http veterinarycancer.com osteosarcoma.html Osteosarcoma from Animal Cancer & Imaging Center http www.vetspecialists.co.uk 06 Animal Welfare Oncology Facts Canine Osteosarcoma.html Canine Osteosarcoma from Davies Veterinary Specialists http www.dogcancerblog.com bone cancer pain new ideas Bone Cancer Pain in Dogs New Ideas from Dr. Demian Drsssler, DVM of Dog Cancer Blog Category Dog diseases Category Cat diseases Category Veterinary oncology ... more details
Codman triangle previously referred to as Codman s triangle is a term used to describe the triangular area of new subperiosteal bone that is created when a lesion, often a tumour, raises the periosteum away from the bone. ref name gpnotebook http www.gpnotebook.co.uk cache 288358364.htm General Practioner s notebook ref A Codman triangle is not actually a full triangle. Instead it is often a pseudotriangle on radiographic findings with ossification on the original bone and one additional side of the triangle which forms a two sided triangle with one open side. This two sided appearance in generated due to a tumor or growth that is growing at a rate which is faster than the periosteum can grow or expand, so instead of dimpling, the periosteum tears away and provides ossification on the second edge of the triangle. ref name PeriostealReaction http www.rad.washington.edu academics academic sections msk teaching materials online musculoskeletal radiology book periosteal reaction Periosteal Reaction ref The main causes for this sign are osteosarcoma , Ewing s sarcoma , eumycetoma , and a subperiosteal abscess . ref name Periosteal Ewing sarcoma http www.ncbi.nlm.nih.gov pubmed 8184073 Periosteal Ewing sarcoma ref ref name Imaging in Classic Osteosarcoma http emedicine.medscape.com article 393927 overview Imaging in Classic Osteosarcoma ref References references med stub Category Skeletal system Eponymous medical signs for integumentary and musculoskeletal systems ja pl Ostroga Codmana pt Tri ngulo de Codman ... more details
Orphan date July 2008 Saos 2 Osteosarcoma Sarcoma osteogenic is a non Transformation genetics transformed cell line derived from the primary osteosarcoma of an 11 year old Caucasian girl since identified as Alice Abernathy in 1973 by Fogh et al . ref cite journal author Fogh J, Fogh JM, Orfeo T year 1977 title One hundred and twenty seven cultured human tumor cell lines producing tumors in nude mice journal J Natl Cancer Inst volume 59 issue 1 pages 221 226 PMID 327080 ref In 1987 Rodan et al . determined that Saos 2 cells possess several osteoblast ic features and could be useful as a permanent line of human osteoblast like cells and as a source of bone related molecules. ref cite journal author Rodan SB, Imai Y, Thiede MA, Wesolowski G, Thompson D, Bar Shavit Z, Shull S, Mann K, Rodan GA year 1987 title Characterization of a human osteosarcoma cell line Saos 2 with osteoblastic properties journal Cancer Res. volume 47 issue 18 pages 4961 6 PMID 3040234 ref Besides their worldwide availability, some of the advantages for using Saos 2 cell line are that they have well documented characterization data, the possibility to obtain large amounts of cells in short time, and the fact that Saos 2 cells can be fully differentiated in a manner that the osteoblastic cells naturally do. ref cite journal author Hausser H J, Brenner RE title Phenotypic instability of Saos 2 cells in long term culture journal Biochem. Biophys. Res. Commun. year 2005 volume 333 issue 1 pages 216 22 PMID 15939397 doi 10.1016 j.bbrc.2005.05.097 ref The latter point is described particularly as the ability of Saos 2 cells to deposit a mineralization competent extracellular matrix , ref cite journal author McQuillan DJ, Richardson MD, Bateman JF title Matrix deposition by a calcifying human osteogenic sarcoma cell line SAOS 2 doi 10.1016 8756 3282 95 90186 8 journal Bone year 1995 volume 16 issue 4 pages 415 26 PMID 7605701 ref which makes these cells a valuable model for studying events associated with the late ... more details
primary bone tumors include osteosarcoma , chondrosarcoma , Ewing s sarcoma , fibrosarcoma , and other ..., Kim JR, Lee SY. MFH of Bone and Osteosarcoma Show Similar Survival and Chemosensitivity. Clin Orthop ... survival in Pediatric Osteosarcoma ref ref http www.thedenverclinic.com images stories Published articles Clin Orthop adult OGS.pdf Survival in Adult Osteosarcoma and MFH of Bone ref Medication One of the major ... more details
Image EpiMetaDiaphyse.jpg thumb Long bone. Captions in German, but region visible labeled as metaphyse . The metaphysis is the wider portion of a long bone adjacent to the epiphyseal plate . ref Dorland s Pocket Medical Dictionary, 27th edition ref This is this part of the bone that grows during childhood as it grows, it ossifies near the diaphysis and the epiphyses. At roughly 18 to 25 years of age, the metaphysis stops growing altogether and completely ossifies into solid bone. Epiphyseal plates growth plates are located in the metaphysis Citation needed date August 2011 and are responsible for growth in the length of the bone. Clinical significance Because of their rich blood supply, metaphysis of long bones are prone to hematogenous spread of osteomyelitis in children. Metaphyseal tumors or lesions include osteosarcoma , chondrosarcoma , fibrosarcoma , osteoblastoma , enchondroma , fibrous dysplasia , simple bone cyst , aneurysmal bone cyst , non ossifying fibroma , and osteoid osteoma . ref name urlInroductory Course cite web url http www.umdnj.edu tutorweb introductory.htm title New Jersey Medical School, Pathology Department Introductory Course on Bone Tumours format work accessdate 2009 03 12 ref References reflist External links UCDavisOrganology Musculoskeletal bone structure0 structure2 Bone, structure Gross, Low developmental biology stub Bone and cartilage Category Skeletal system Category Long bones da Metafyse de Metaphyse es Met fisis fr M taphyse pt Met fise ru fi Metafyseaalinen ... more details
Chembox ImageFile SB431542.png ImageSize ImageAlt IUPACName OtherNames Section1 Chembox Identifiers CASNo PubChem ChEMBL 440084 SMILES NC O c1ccc cc1 c2nc c3ccc4OCOc4c3 c nH 2 c5ccccn5 Section2 Chembox Properties Formula C22H16N4O3 MolarMass 384.4 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition SB 431542 is a drug candidate developed by GlaxoSmithKline GSK as an Enzyme inhibitor inhibitor of the activin receptor like kinase ALK Receptor biochemistry receptor s, ALK5, ALK4 and ALK7. It also suppressed the TGF beta induced proliferation of osteosarcoma cells in humans. ref Cite journal pmid 12065755 volume 62 issue 1 pages 58 64 last Laping first NJ coauthors Grygielko E, Mathur A, Butter S, Bomberger J, Tweed C, Martin W, Fornwald J, Lehr R, Harling J, Gaster L, Callahan JF, Olson BA title Inhibition of transforming growth factor TGF beta1 induced extracellular matrix with a novel inhibitor of the TGF beta type I receptor kinase activity SB 431542 journal Molecular Pharmacology year 2002 doi 10.1124 mol.62.1.58 ref References reflist Category Protein kinase inhibitors Category Imidazoles Category Benzodioxoles Category Amides fa ... more details
OSLAM syndrome is a rare autosomal dominant hereditary disorder . OSLAM is an initialism that stands for osteosarcoma , limb anomalies, and erythroid macrocytosis with megaloblastic marrow syndrome . OSLAM syndrome was recognised and described by Mulvilhill et al. as a syndrome that increases susceptibility to tumours and is characterised by an impaired regulation of bone and marrow development. ref Mulvihill J.J., Gralnick H.R., Whang Peng J., Leventhal B.G. 1977. Multiple childhood osteosarcomas in an American Indian family with erythoid macrocytosis and skeletal anomalies, Cancer , 40 6 3115 3122. ref ref Weber G.F. 2007. Molecular Mechanisms of Cancer , Springer, pg. 558. ref Individuals with OSLAM syndrome have an elevated risk of bone cancer, limb abnormalities, and enlarged red blood cells. Symptoms Bone cancer. Clinodactyly Curved fifth fingers clinodactyly with brachymesophalangy. Absence of one digital ray of the foot. Bilateral radioulnar synostosis. Macrocytosis Enlarged red blood cells . Dental decay. Short stature. See also Li Fraumeni syndrome References reflist Category Osseous and chondromatous neoplasia Category Sarcoma Category Hereditary cancers Category Syndromes health stub ... more details
Infobox basketball biography photo caption position Small Forward name Xu Yong height ft 6 height in 8 weight lb 220 team Shanghai Dongfang Sharks league Chinese Basketball Association nationality CHN birth date Birth date and age 1989 03 30 mf y birth place Shanghai , People s Republic of China China highschool college draft Undrafted draft year draft team career start 2004 career end 2008 Chinese name Xu surname Xu Xu Yong , born March 30, 1989 in Shanghai , People s Republic of China China was a China Chinese professional basketball player. ref http www.draftexpress.com profile Xu Yong 5149 , draftexpress.com, accessed 7 April 2011. ref He lastly played for the Shanghai Dongfang Sharks of the Chinese Basketball Association . Xu Yong was often considered as one of Chinas major basketball talents, third only to Yao Ming and Yi Jianlian . After several dominating performances in the Chinese Basketball Association , Xu had to end his basketball career at age 19 after being diagnosed with osteosarcoma . ref http www.fiba.com pages eng fc news lateNews p newsid 25161 arti.html , fiba.com, accessed 7 April 2011. ref Career overview Xu Yong came out of the youth program of Yao Ming s Shanghai Dongfang Sharks . He caught the attention of many experts through his MVP award at the Adidas Asia Camp in 2005. Later, he played for The Bush School in Seattle . At the 2007 FIBA Under 19 World Championship , he averaged 15.8 points, 3.8 rebounds and 2.1 assists on a underperforming Chinese team. In the Chinese Basketball Association , he averaged 18.2 points, 6.3 rebounds and 3.4 assists throughout the regular season with tremendous improvements towards the end of the season. ref http www.draftexpress.com profile Xu Yong 5149 , draftExpress.com, accessed 7 April 2011. ref Many experts saw him as China s next major NBA prospect. ref http www.nbadraft.net players xu yong , NBADraft.net, accessed 8 April 2011. ref Accordingly, the diagnosis of osteosarcoma and subsequent end of his ... more details
Now . The mission of the Shiri Foundation was to raise money to fund osteosarcoma research. In 2006 ... to focusing on organizing proms and suspending efforts to raise funds for osteosarcoma research. In 2009 ... in Spring 2012. Shirts In 2006, Scarf was unsuccessful at raising enough money for osteosarcoma ... more details
, in the era before chemotherapy, long term survival for patients with localized osteosarcoma ... C, De Paolis M, Mercuri M, Bacci G title Primary bone osteosarcoma in the pediatric age state of the art ... 3 Malignant Hemangioendothelioma 9130 3 Malignant Schwannoma 9560 3 9561 3 Osteosarcoma 9180 3 9190 ... 9220 3 Extraskeletal osteosarcoma 9180 3 Fibrosarcoma 8810 3 Hemangiopericytoma 9150 Also ... 10 19 ref Osteosarcoma is treated with surgical resection of as much of the cancer as possible, often ... in children. Most high grade bone sarcomas, including Ewing s sarcoma and osteosarcoma , are much more ... more details
trade name Mepact , marketed by Takeda Pharmaceutical Company Takeda is a drug against osteosarcoma ... Survival in 20 Years Now Available for Patients With Osteosarcoma Bone Cancer publisher Takeda date ... Osteosarcoma date 2009 03 09 publisher PR Newswire accessdate 2009 11 12 ref ref cite news url http ... for treatment of osteosarcoma date 2007 08 28 publisher The Medical News accessdate 2009 ... resectable osteosarcoma following complete surgical removal in children, adolescents and young adults ... 2009 11 12 ref Osteosarcoma is a type of bone cancer diagnosed in about 1,000 individuals in Europe ... 800 newly diagnosed osteosarcoma patients, mifamurtide was combined with the chemotherapeutic agents ... more details
Interventions infobox Name PAGENAME Image Hemipelvectomy gas gangrene.jpg Caption Hemipelvectomy being performed on a patient suffering from gas gangrene . ICD10 ICD9 ICD9 mult MeshID D006428 OPS301 OtherCodes A hemipelvectomy is a high level pelvic amputation . Along with hip disarticulations, hemipelvectomies are the rarest of lower extremity amputations. In some cases, an internal hemipelvectomy can be performed, which is a limb sparing procedure. A complete hemipelvectomy, however, is the amputation of half of the pelvis and the leg on that side. This type of procedure is also called transpelvic amputation . Hemipelvectomies may be required for several reasons, such as a car accident or cancer. Examples of cancers that can require hemipelvectomies are sarcoma s like Ewing s Sarcoma , osteosarcoma or chondrosarcoma . People who have experienced a hemipelvectomy may or may not be able to use a prosthesis . They may use adaptive devices such as a wheelchair , underarm crutches , forearm crutches, or, in the case of internal hemipelvectomies, a Cane medical device cane . Physical therapy can be useful to those with hemipelvectomies to build strength and prevent problems like back pain and scoliosis . Because a hemipelvectomy is a rare type of amputation, it is important that the physical therapist is trained in the special needs of a post hemipelvectomy patient. There are two types of hemipelvectomy External Amputation of the whole leg plus the pelvis on that side. The other name for external hemipelvectomy is called a hindquarter amputation. Internal Removal of the pelvis on the one side, but the leg is saved. External links http www.hphdhelp.org Hemipelvectomy and Hip Disarticulation Help http www.amputee coalition.org Amputee Coalition of America http www.beenamputatie.nl Dutch hemipelvectomy site Muscle soft tissue procedures Surgery stub Category Surgical oncology Category Surgical removal procedures de Hemipelvektomie it Emipelvectomia ... more details
orphan date November 2007 Ivy S. Gunter born June 22, 1950 in Bellevue, Ohio ref name Royster cite book last Royster first Jacqueline Jones title Profiles of Ohio women, 1803 2003 year 2003 publisher Ohio University Press isbn 9780821415085 pages 203 url http books.google.com books?id tV3CKGuGoRkC&pg PT219&lpg PT219&dq v onepage&q&f false ref is an amputee , fashion model , osteosarcoma survivor, inspirational speaker , and Physical fitness fitness enthusiast. She is the author of the book On the Ragged Edge of Drop Dead Gorgeous . ref name Coping cite web last Phiffer first Cindy title Ivy Gunter Supermodel url http copingmag.com cwc index.php celebrities celebrity article ivy gunter publisher Coping with Cancer accessdate 29 December 2010 date September October 1999 ref ref name ODJFS cite web title Ohio Women s Hall of Fame Bio url http www.odjfs.state.oh.us women halloffame bio.asp?ID 116 publisher ODJFS accessdate 29 December 2010 ref In early 1980 she was diagnosed with bone cancer in her right leg, leading to its amputation . ref name King cite book last King first Dean title Cancer Combat year 1998 publisher Bantam Books isbn 9780553378450 pages 18 coauthors Jessica King, Jonathan Pearlroth ref Five months after surgery, she returned to filming, with wigs and a prosthesis prosthetic leg . She returned to modeling shortly thereafter. Gunter was inducted into the Ohio Women s Hall of Fame in 1993. ref name ODJFS References Reflist Persondata Metadata see Wikipedia Persondata . NAME Gunter, Ivy ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 22 June 1950 PLACE OF BIRTH Bellevue, Ohio DATE OF DEATH PLACE OF DEATH DEFAULTSORT Gunter, Ivy Category American memoirists Category American female models Category American amputees Category 1950 births Category Living people ... more details
Dz13 is an experimental treatment developed by Australia n scientists which aims to combat a range of illnesses from diabetes to Heart Disease heart disease and cancer . How it works Dz13 is a Deoxyribozyme DNAzyme that targets c Jun , a transcription factor found in diseased blood vessels, eyes, lungs and joints. The treatment works by destroying RNA , essentially inhibiting c Jun expression in cells. ref name Dass2008 The potential of Dz13 as a therapeutic derives from the fact that inactivation of c Jun can have an effect on Upstream and downstream transduction downstream gene genes such as MMP 2 , MMP 9 , VEGF and FGF 2 . ref name Fahmy2006 Dz13 in cancer Dz13 has been shown to inhibit tumour growth and angiogenesis . ref name Fahmy2006 Anti cancer effects have been demonstrated in models of prostate cancer , breast cancer and osteosarcoma . ref name Tan2010 Clinical trials of Dz13 in patients with skin cancer basal cell carcinoma commenced in 2010. ref name ACT2010 References Reflist refs ref name Dass2008 Dass, C.R. et al 2008 . DNAzyme technology and cancer therapy cleave and let die. Mol Cancer Ther. 7 2 243 51. ref ref name Fahmy2006 Fahmy, R. et al 2006 . Suppression of vascular permeability and inflammation by targeting of the transcription factor c Jun. Nat Biotechnol. 24 7 856 863. ref ref name Tan2010 Tan, M.L. et al 2010 . Direct anti metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP 2, MMP 9 and MT1 MMP in tumours. Cancer Cell Int. 10 9. ref ref name ACT2010 Australian Cancer Trials 2010 . A phase I study of the Dz13 drug targeting the c Jun gene in subjects with skin cancer nodular basal cell carcinoma . http www.australiancancertrials.gov.au search clinical trials search results clinical trials details.aspx?TrialID 335133&ds 1 . ref External links http www.smh.com.au news National New super drug may combat cancer 2006 07 03 1151778858991.html New super drug may combat cancer Category Experimental medical treatments ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD10 M 80 m 80 ICD10 M 90 m 86 ICD9 ICD9 730 ICD9 733 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D001847 Bone disease refers to the medical conditions which affect the bone . Terminology See Osteopathy A bone disease is also called an osteopathy , but because the term osteopathy is often used to refer to a Pseudoscience pseudo scientific health care technique, use of the term can cause some confusion. Bone and cartilage disorders Main Osteochondrodysplasia Osteochondrodysplasia is a general term for a disorder of the development dysplasia of bone osteo and cartilage chondro . List B Bone cyst Bone spur Osteophytes Bone tumor C Craniosynostosis Coffin Lowry syndrome F Fibrodysplasia ossificans progressiva Fibrous dysplasia Fong Disease or Nail patella syndrome G Giant cell tumor of bone Greenstick Fracture H Hypophosphatasia K Klippel Feil syndrome M Metabolic Bone Disease N Nail patella syndrome O Osteoarthritis Osteitis deformans or Paget s disease of bone Osteitis fibrosa cystica or Osteitis fibrosa , or Von Recklinghausen s disease of bone Osteitis pubis Condensing osteitis or Osteitis condensans Osteitis condensans ilii Osteochondritis dissecans Osteochondroma Bone Tumor Osteogenesis Imperfecta Osteomalacia Osteomyelitis Osteopenia Osteopetrosis Osteoporosis Osteosarcoma Bone Tumor Osteonecrosis P Porotic hyperostosis Primary hyperparathyroidism R Renal Osteodystrophy S Salter Harris fractures W Water on the knee See also Osteoimmunoology External links http www.nlm.nih.gov medlineplus bonediseases.html disease stub Medical conditions Osteochondropathy Category Musculoskeletal disorders ... more details
orphan date May 2009 Thaddeus P. Dryja , MD is a physician and noted biomedical researcher. A 1976 graduate of Yale Medical School , he specializes in ophthalmology and is recognized for his 1986 discovery of the Rb tumor suppressor gene, mutations in which lead to a cancer of the eye known as retinoblastoma . He was elected to the United States National Academy of Sciences National Academy of Sciences in 1996, and currently is Professor of Ophthalmology at Harvard Medical School . He led a research group at the Massachusetts Eye and Ear Infirmary in Boston, Massachusetts, USA, where his group identified the first gene to cause typical retinitis pigmentosa the rhodopsin gene . In 2006 he started work at the Novartis Institutes for Biomedical Research, where he currently is Vice President and Global Head of Ophthalmology Research. References Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 1986 323 643 6. PMID 2877398. Dryja TP, McGee TL, Reichel E, Hahn LB, Cowley GS, Yandell DW, Sandberg MA, Berson EL. A point mutation of the rhodopsin gene in one form of retinitis pigmentosa. Nature 1990 343 364 366 External links http www.meei.harvard.edu shared staff ophthodocs tdryja.htm Persondata Metadata see Wikipedia Persondata . NAME Dryja, Thad ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Dryja, Thad Category Yale School of Medicine alumni Category Harvard Medical School faculty Category Living people Category American medical researchers Category Members of the United States National Academy of Sciences Category Year of birth missing living people US med bio stub ... more details
No footnotes date March 2009 yvind S. Bruland born 1952 is a professor of Clinical Oncology and faculty of Medicine at the University of Oslo . Bruland holds a B.Sc. , Doctor of Medicine M.D and Ph.D. from the University of Oslo , Norway . His research includes primary bone and soft tissue cancer s sarcoma s and skeletal metastases from prostate cancer and breast cancer targeted radionuclide therapy , for instance the clinical development of Alpharadin , based on Radium 223 the tumor biology and prognostic impact of micro metastases in bone marrow aspirates on patients with primary bone cancer osteosarcoma external beam radiotherapy and the radiotherapy of skeletal metastases and soft tissue sarcomas. He has served as supervisor to twelve Ph.D students, nine so far having completed their Ph.D. theses. In 2008 he was elected as a member of the Norwegian Academy of Science and Letters . References http www.algeta.com default.asp?menuID 4308&smenuID 4310 Alpharadin trial treatment of cancer with skeletal metastasis http www.thelancet.com journals lanonc article PIIS1470 2045 07 70147 X abstract Lancet publication of Alpaharadin phase II results http www.algeta.com xml press underside.asp?xml http cws.huginonline.com A 134655 PR 200902 1286756.xml&menuID 4447 US Approval for phase III testing of Alpharadin http search2.google.cit.nih.gov search?site NIH Master&client NIHNEW frontend&proxystylesheet NIHNEW frontend&output xml no dtd&filter 0&getfields &q Alpharadin&btnG.x 22&btnG.y 10&btnG search US National Institute of Health information on Alpharadin http bruland.info index.php?mid 2&k bruland Pubmed Publications according to PubMed http www.bruland.info yvind S. Bruland, further information Persondata Metadata see Wikipedia Persondata . NAME Bruland, Oyvind S. ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 1952 PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Bruland, Oyvind S. Category 1952 births Category Living people Category University of Oslo alumni ... more details
Italic title Taxobox name Spirocerca lupi regnum Animal ia phylum Nematoda classis Secernentea ordo Spirurida familia Spirocercidae genus Spirocerca species S. lupi binomial Spirocerca lupi binomial authority Spirocerca lupi is a species of nematode . ref name pmid17512766 cite journal author van der Merwe LL, Kirberger RM, Clift S, Williams M, Keller N, Naidoo V title Spirocerca lupi infection in the dog a review journal Vet. J. volume 176 issue 3 pages 294 309 year 2008 month June pmid 17512766 doi 10.1016 j.tvjl.2007.02.032 url http linkinghub.elsevier.com retrieve pii S1090 0233 07 00098 6 ref In dogs, infestation can cause osteosarcoma of the esophagus . ref name Ranen cite journal author Ranen E, Lavy E et al. year 2004 title Spirocercosis associated esophageal sarcomas in dogs. A retrospective study of 17 cases 1997 2003 journal Vet Parasitol 119 2 3 209 21 volume 119 pages 209 doi 10.1016 j.vetpar.2003.10.023 ref Doramectin has been used against it. ref name pmid13129670 cite journal author Lavy E, Harrus S, Mazaki Tovi M, et al. title Spirocerca lupi in dogs prophylactic effect of doramectin journal Res. Vet. Sci. volume 75 issue 3 pages 217 22 year 2003 month December pmid 13129670 doi 10.1016 S0034 5288 03 00115 2 url http linkinghub.elsevier.com retrieve pii S0034528803001152 ref References reflist Category Nematodes nematode stub he ... more details
and treatment of primary bone cancer, and in particular of osteosarcoma and Ewing s sarcoma. BCRT Website ... information on osteosarcoma and Ewing s sarcoma and a glossary medical dictionary. BCRT ... more details
who are at increased risks for osteosarcoma. This includes those with Paget s disease of bone ... are nausea, leg cramps and dizziness. The main risk of teriparatide is an increased risk of osteosarcoma ... after the injections began. Cases of bone tumor and osteosarcoma have been reported rarely in the postmarketing ... more details
tumors such as an osteosarcoma . Frequency In the US, Osteoblastomas account for only 0.5 2 of all ... to that of osteosarcoma . This variant is also more likely to recur after surgery than is conventional ... and the initial lesion was an osteosarcoma, since histologic differentiation of these two entities ... more details
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