- Therapies under investigation for multiple sclerosis
It seems that its mechanism of action is peroxynitrite inactivation ref cite journal pmid 19425822 ... uric acid levels protects against blood brain barrier destruction through peroxynitrite scavenging . ref cite journal author Kean RB, Spitsin SV, Mikheeva T, Scott GS, Hooper DC title The peroxynitrite ... cgi content full 165 11 6511 date December 1, 2000 ref Peroxynitrite has been correlated with the axons ... more details
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- CKMT2
author Wendt S, Schlattner U, Wallimann T title Differential effects of peroxynitrite on human ... more details
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- RNF7
Kim SY, Lee JH, Yang ES, et al. title Human sensitive to apoptosis gene protein inhibits peroxynitrite ... more details
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- Reactive oxygen species
location New York, N.Y year 1999 chapter The biochemistry of nitric oxide and peroxynitrite implications ... more details
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- Aconitase
by peroxynitrite modulation by citrate and glutathione journal Biochemistry volume 44 issue ... more details
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- Antioxidant effect of polyphenols and natural phenols
chelation reactions. Various reactive oxygen species , such as singlet oxygen , peroxynitrite and hydrogen ... more details
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- Plant disease resistance
peroxide, or peroxynitrite, or more complex phytoalexins such as genistein or camalexin Antimicrobial ... more details
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- Joe M. McCord
. Quijano, D. Hernandez Saavedra, L. Castro, J.M. McCord, B.A. Freeman and Rafael Radi, Reaction of peroxynitrite ... more details
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- Multiple chemical sensitivity
Elevated nitric oxide peroxynitrite theory of multiple chemical sensitivity central role of N methyl ... to MCS. ref name McKeown et al. 2004 Pall has suggested elevated nitric oxide and peroxynitrite NO ONOO ... and stimulation by peroxynitrite, nitric oxide, and organic solvents as the mechanism of chemical ... more details
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- Antioxidant
SV title Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood CNS barrier permeability ... name Santos1999 cite journal pages 285 94 doi 10.1006 abbi.1999.1491 title Uric Acid Oxidation by Peroxynitrite ... oxidants, such as superoxide , but does act against peroxynitrite , ref name Sautin2008 cite journal ... more details
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- Human serum albumin
Peroxynitrite Isomerization by Ferric Human Serum Heme Albumin journal J. Biol. Chem. volume ... more details
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- NADH dehydrogenase
form of Complex I was susceptible to inhibition by nitrosothiols and peroxynitrite ... more details
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- Ginseng
oxide, superoxide, hydroxyl radical and peroxynitrite scavenging activities compared with conventionally ... more details
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- List of Guggenheim Fellowships awarded in 2003
Intercellular diffusion and toxicity of peroxynitrite. Mirta Noem Rosenberg , Poet and Translator, Buenos ... more details
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- Discovery and development of cyclooxygenase 2 inhibitors
occurring reducing agents. BH sub 4 sub is sensitive to oxidation by peroxynitrite ONOO sup sup ... more details
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- Homogenized Milk and Atherosclerosis
and hydrogen peroxide , producing attendant, biochemical cascade reactions, which can lead to peroxynitrite formation. Peroxynitrite is highly toxic and results in cell death or necrosis . Over a wider ... more details
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- Pathophysiology of multiple sclerosis
of peroxynitrite . ref cite journal author Kean R, Spitsin S, Mikheeva T, Scott G, Hooper D title The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous ... more details
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- Superoxide dismutase
and critical cellular targets. For example, it reacts the NO radical, and makes toxic peroxynitrite ... more details
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- Uric acid
. title Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis ... more details
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- Nitric oxide
following a period of ischemia reacts with superoxide to produce the damaging oxidant peroxynitrite ... more details
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- Substituted amphetamine
of Radical chemistry free radicals and peroxynitrite , which is a strong oxidizer. MDMA, moreover ... more details
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- Neurotoxin
. S. 1990 Apparent Hydroxyl Radical Production by Peroxynitrite Implications for Endothelial Injury ... more details
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- Oxygen toxicity
increase the formation of other free radical s, such as nitric oxide , peroxynitrite , and trioxidane ... more details
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- Carbon monoxide poisoning
radicals including peroxynitrite . ref name JToxClinTox1994 hardy In the brain this causes further ... more details
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