About the congenital disorder disease the paleontological application Polydactyly in early tetrapods Refimprove date June 2008 Infobox Disease Name Polydactyly Image Polydactyly.jpg Caption 27 year old male with unilateral polydactyly affecting the left thumb. The supernumerary digit had normal sensation ... ICD9 755.0 ICDO OMIM 603596 MedlinePlus eMedicineSubj derm eMedicineTopic 692 MeshID D017689 Polydactyly ..., N. 2009, November 2 . Polydactyly. Retrieved December 4, 2010, http www.umm.edu ency article 003176.htm ref Presentation File Polydactyly 01 Lfoot AP.jpg thumb Left foot with postaxial polydactyly of 5th ray File Polydactyly 01 Lhand AP.jpg thumb Left hand with mid ray duplication The extra ... thumb , and central ring, middle, index fingers polydactyly. The extra digit is most commonly an abnormal ... Cite web last Eaton first Charles title Polydactyly Extra Fingers url http www.eatonhand.com hw hw024.htm ... Akshat Saxena born 34 fingers toes breaks world record.html?ito feeds newsxml ref Genetics Polydactyly ... trait . ref Cite web title Polydactyly and Syndactyly publisher Milton S. Hershey ... But mutation in a variety of genes can give rise to polydactyly. Typically the mutated gene is involved in developmental patterning, and a syndrome of congenital anomalies results, of which polydactyly ... III ? OMIM2 174700 Preaxial IV GLI3 at 7p13 Syndromes including polydactyly include Acrocallosal ... Hall syndrome , Rubinstein Taybi syndrome , Short rib polydactyly , and VATER association . ref ... thumb . Epidemiology File Wanitetlefthand.jpg thumb Left hand with postaxial polydactyly. The condition ... Postaxial hand polydactyly is a common isolated disorder in African black and African American children, and autosomal dominant transmission is suspected. Postaxial polydactyly is more frequent in blacks .... authorlink coauthors David Zieve title Polydactyly publisher Penn Medicine date 11 February 2009 url ... 2010 ref In contrast, postaxial polydactyly seen in white children is usually syndromic and associated ... more details
Context date October 2009 Infobox Disease Name Majewski& 39 s polydactyly syndrome Image Caption DiseasesDB 32793 ICD10 ICD9 ICDO OMIM 263520 MedlinePlus eMedicineSubj eMedicineTopic MeshID Majewski s polydactyly syndrome , also known as polydactyly with neonatal chondrodystrophy type I, short rib polydactyly syndrome type I , and short rib polydactyly syndrome , is a lethal form of neonatal dwarfism characterized by osteochondrodysplasia skeleton skeletal abnormalities in the development of bone and cartilage with a narrow thorax , syndactyly polysyndactyly , disproportionately short tibia e, thorax dysplasia, hypoplastic lungs and respiratory insufficiency. Associated anomalies include protruding abdomen, brachydactyly , peculiar faces, hypoplastic epiglottis , cardiovascular defects , renal cysts, and also genital anomalies. Death occurs before or at birth. The disease is inherited in an autosomal recessive pattern. It was characterized in 1971. ref cite pmid 4331366 ref References reflist Osteochondrodysplasia Category Congenital disorders Category Growth disorders Category Genetic disorders with OMIM but no gene Category Article Feedback 5 disease stub nl Majewskisyndroom pl Zesp Majewskiego ... more details
Infobox Disease Name Short rib polydactyly syndrome Image Caption DiseasesDB 32791 DiseasesDB mult DiseasesDB2 32793 DiseasesDB2 32792 DiseasesDB2 32795 ICD10 ICD10 Q 77 2 q 65 ICD9 ICD9 756.5 ICDO OMIM 263530 OMIM mult OMIM2 263520 OMIM2 263510 OMIM2 269860 MedlinePlus eMedicineSubj eMedicineTopic MeshName Short Rib Polydactyly Syndrome MeshNumber C05.116.099.708.857 Short rib polydactyly syndrome is a family of four closely related dysplasia s I Saldino Noonan type II Majewski s polydactyly syndrome Majewski type III Verma Naumoff type associated with DYNC2H1 ref name pmid19361615 cite journal author Merrill AE, Merriman B, Farrington Rock C, et al. title Ciliary abnormalities due to defects in the retrograde transport protein DYNC2H1 in short rib polydactyly syndrome journal Am. J. Hum. Genet. volume 84 issue 4 pages 542 9 year 2009 month April pmid 19361615 pmc 2667993 doi 10.1016 j.ajhg.2009.03.015 url http linkinghub.elsevier.com retrieve pii S0002 9297 09 00112 8 ref IV Beemer Langer type References reflist Osteochondrodysplasia Cytoskeletal defects disease stub Category Growth disorders pl Zesp kr tkie ebro polidaktylia ru ... more details
Eleventh finger may refer to Polydactyly , a congenital anomaly in humans having supernumerary fingers or toes Pelvic digit , a congenital anomaly in humans, in which bone tissue develops in the soft tissue near the pelvis disambig This comment is here to prevent this page from being listed at special shortpages This comment is here to prevent this page from being listed at special shortpages ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D017880 Congenital limb deformities are congenital musculoskeletal system musculoskeletal disorders which primarily affect the upper and lower limbs. An example is polydactyly . External links http embryology.med.unsw.edu.au Notes skmus72.htm medicine stub Congenital malformations and deformations of musculoskeletal system Multiple abnormalities Category Congenital disorders of musculoskeletal system ... more details
of inheritance. Summary Other names for acropectoral syndrome include ACRPS, Syndactyly , preaxial polydactyly ... Nov. 2011 ref This syndrome is characterized by syndactyly of all fingers toes, pre axial polydactyly ... of the 22 individuals had pre axial polydactyly , as well had a blind ending U shaped sinus in the chest ... , tarsal , and metatarsal synostoses as well as the preaxial polydactyly that occurred in the feet ... inherited types of preaxial polydactyly, including preaxial polydactyly type II PPD2 , preaxial polydactyly type III PPD3 and triphalangeal thumb polysyndactyly TPT PS . ref name pmid11333865 ... where preaxial polydactyly and triphalangeal thumb polysyndactyly had previously been mapped. This study ... . Previously, preaxial polydactyly and sternal defects have been linked to ectopic expression of the gene ... in mice. Dundar and coworkers found that the LMBR1 gene links to pre axial polydactyly . This gene ... of the 22 individuals had pre axial polydactyly in the hands unilateral in two, bilateral in six , ranging ... tissue web between the thumb and index finger. Fourteen had preaxial polydactyly in the feet unilateral ... more details
The Ho Kaufman Mcalister Syndrome , also known as the Chen Kung Ho Kaufman Mcalister Syndrome, is a rare congenital malformation syndrome where infants are born with a cleft palate , micrognathia , Wormian bones, congenital heart disease , dislocated Hip anatomy hips , bowed fibulae , preaxial polydactyly of the feet, abnormal skin patterns, and most prominently, missing tibia . The etiology is unknown. The Ho Kaufman Mcalister Syndrome is named after Chen Kung Ho , R.L. Kaufman , and W.H. Mcalister who first described the syndrome in 1975 at Washington University in St. Louis . It is considered a rare disease by the Office of Rare Diseases ORD of the National Institutes of Health NIH . References http www.ncbi.nlm.nih.gov entrez query.fcgi?cmd Retrieve&db pubmed&dopt Abstract&list uids 168764&query hl 29 Ho Kaufman Mcalister Syndrome Summary at PubMed Ho CK, Kaufman RL, Mcalister WH 1975 . Congenital Malformations Cleft Palate, Congenital Heart Disease, Absent Tibiae, and Polydactyly. American Journal of Diseases of Children 1975 Jun. 129 6 714 6. Category Congenital disorders Category Syndromes es S ndrome de Ho Kaufman Mcalister ... more details
Image Kiev UkrainianNationalChernobylMuseum 15.jpg thumb piglet with dipygus at Ukrainian National Chernobyl Museum in Kiev Dysmelia from Greek language Greek bad plus plural limb is a congenital disorder referring to the limbs. ref DorlandsDict three 000033112 Dysmelia ref Types Dysmelia can refer to missing aplasia Limb anatomy limbs amelia birth defect amelia , oligodactyly , congenital amputation malformation of limbs ectrodactyly , phocomelia , meromelia , Syndactyly Syndactyly syndactyly , brachydactyly , clubfoot too many limbs polymelia , polydactyly , polysyndactyly Occurrence rate Birth defects involving limbs occur in 1 per 1000. Fact date September 2007 Causes Dysmelia can be caused by inheritance of abnormal genes , e.g. polydactyly , ectrodactyly or brachydactyly , symptoms of deformed limbs then often occur in combination with other symptoms syndrome s external causes during pregnancy thus not inherited , e.g. via amniotic band syndrome teratogenesis teratogenic drugs e.g. thalidomide , which causes phocomelia or environmental chemicals ionizing radiation nuclear weapon s, radioiodine , radiation therapy infections metabolic imbalance References reflist Category Congenital disorders of musculoskeletal system med stub Congenital malformations and deformations of musculoskeletal system de Dysmelie it Micromelia no Dysmeli pl Dysmelia sv Dysmeli ... more details
Disorders of the skin Athlete s foot Callus and Corns of the Skin Ingrown nail Onychocryptosis Ingrown Toenail Keratosis Keratosis palmaris et plantaris Disorders of the joints Hallux valgus bunion Hallux varus Diabetic Arthropathy Neuropathic joint disease Charcot Foot Rheumatoid arthritis Osteoarthritis Disorders of the bones Fracture bone Fracture Jones Fracture Dupuytren fracture or Pott s fracture Osteomyelitis Disorders of the nerves Tarsal tunnel syndrome Neuroma Metatarsalgia Nerve entrapment Combined disorders Pes cavus Cavus foot Club foot Genetic disorders Polydactyly Specific manifestations of systemic disease Diabetic foot Rheumatoid arthritis Rheumatoid foot Neuropathy Plantar fasciitis Category Medical lists Foot and ankle disorders ... more details
Italic title Automatic taxobox name Ichthyostegidae fossil range Fossil range 365 Late Devonian image Ichthyostega BW.jpg image width 250px image caption Ichthyostega , the nominal genus authority Erik Jarvik Jarvik , 1952 subdivision div Ichthyostega extinction Hynerpeton extinction Portal Paleontology The Ichthyostegidae is a small family of extinct Labyrinthodontia labyrinthodont amphibian from the Devonian . All members of the family were relatively large animals with primitively Polydactyly in early tetrapods polydactyl , paddle like feet. Two genera are assigned to the family the nominal Ichthyostega from Greenland and Hynerpeton found in Pennsylvania , U.S.A . Bout appear to have been fairly capable on dry land, when compared with the contemporary Acanthostegidae Acanthostegids . Category Prehistoric vertebrates Category Tetrapods Category Devonian animals ... more details
, Cardi cat, Ithacat, and Vermont snowshoe cat. Occurrence The true polydactyly is a congenital abnormality ..., and the number of toes on either the front or rear paws is typically the same. Polydactyly is most commonly found on the front paws only, it is rare for a cat to have polydactyl hind paws only, and polydactyly ... there is a specific double paw condition, although this condition may be interrelated with polydactyly. ref name messybeast Feline radial hypoplasia see squitten is a mimic of polydactyly and is considered ... as patty feet or hamburger feet . Though this looks less serious than true polydactyly as the feet ... of polydactyly among the cat population of various ports correlates with the dates when they first ... basis of the condition however indicates that many different mutations can all lead to polydactyly ... regulatory output responsible for preaxial polydactyly journal Human Molecular Genetics date 1995 02 ... Polydactyl Cats Part 1 accessdate 2007 01 20 ref Caring for a polydactyl cat This type of polydactyly ... have more difficulty in learning to walk than normal animals however in some cases polydactyly ... 217, 1961 Danforth CH Heredity of polydactyly in the cat. Journal of Heredity 38 107, 1947 Danforth ... assortmant of dominant white and polydactyly in the cat Journal of Cat Genetics 1 16 17, 1964 Vella ... Heinemann Ltd 19 Aug 1999 Wenthe, M Lazarz, B A case of atavistic polydactyly at the hind limb ... more details
Impossible Syndrome , or Chondrodysplasia situs inversus imperforate anus polydactyly , is a complex combination of human congenital malformations Congenital disorder birth defects . ref name Fraser cite journal author Fraser FC, Jequier S, Chen MF title Chondrodysplasia, situs inversus totalis, cleft epiglottis and larynx, hexadactyly of hands and feet, pancreatic cystic dysplasia, renal dysplasia absence, micropenis and ambiguous genitalia, imperforate anus journal Am J Med Genet. volume 34 issue 3 pages 401 405 year 1989 pmid 2596528 doi 10.1002 ajmg.1320340316 ref The malformations include chondrodysplasia improper growth of bone and cartilage , Situs inversus situs inversus totalis chest and abdominal organs all a mirror image of normal , cleft epiglottis and larynx , Polydactyly hexadactyly six digits on hands and feet, Congenital diaphragmatic hernia diaphragmatic hernia , Pancreas pancreatic abnormalities, kidney abnormal on one side and absent on the other side, micropenis and ambiguous Sex organ genitalia , and imperforate anus . Only one case of Impossible Syndrome has been reported the infant was Premature birth premature and Stillbirth stillborn . Genetics Image autorecessive.svg thumb right Impossible syndrome has an autosomal recessive pattern of inheritance. The inheritance of Impossible syndrome is suspected to be autosomal recessive , which means the affected gene is located on an autosome , and two copies of the gene one from each parent are required to have an infant with the disorder. References reflist External links http www.orpha.net consor cgi bin OC Exp.php?Lng GB&Expert 1424 Overview at Orphanet Phakomatoses and other congenital malformations not elsewhere classified DEFAULTSORT Impossible Syndrome Category Autosomal recessive disorders Category Rare diseases Category Syndromes Category Genetic disorders with no OMIM Genetic disorder stub ... more details
Infobox Disease Name Acrocallosal syndrome Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 200990 MedlinePlus eMedicineSubj eMedicineTopic MeshID D055673 Acrocallosal syndrome also known as ACLS is a rare autosomal recessive syndrome characterized by corpus callosum agenesis , polydactyly , multiple dysmorphic feature s, motor and mental retardation, and other symptoms. ref OMIM 200990 Acrocallosal syndrome ACLS ref The syndrome was first described by Albert Schinzel in 1979. ref cite journal first Albert last Schinzel title Postaxial polydactyly, hallux duplication, absence of the corpus callosum, macroencephaly and severe mental retardation a new syndrome? journal Helvetica Paediatrica Acta volume 34 issue 2 pages 141 6 year 1979 month May doi pmid 457430 ref It is associated with GLI3 . ref name pmid12414818 cite journal author Elson E, Perveen R, Donnai D, Wall S, Black GC title De novo GLI3 mutation in acrocallosal syndrome broadening the phenotypic spectrum of GLI3 defects and overlap with murine models journal J. Med. Genet. volume 39 issue 11 pages 804 6 year 2002 month November pmid 12414818 pmc 1735022 doi 10.1136 jmg.39.11.804 url http jmg.bmj.com cgi pmidlookup?view long&pmid 12414818 ref References references External links RareDiseases 5721 Acrocallosal syndrome, Schinzel type Congenital malformations and deformations of nervous system Transcription factor coregulator deficiencies Category Autosomal recessive disorders Category Rare diseases Category Syndromes disease stub ... more details
Unreferenced auto yes date December 2009 Georges Bardet 1885 ? was a France French physician who is known for first describing a rare genetic disease. In his graduation thesis at the University of Paris in 1920, Bardet wrote about a medical condition characterized by obesity , retinitis pigmentosa , polydactyly and hypogonadism . Two years later, Hungarian physician Arthur Biedl described the same symptoms in two sisters, separate from Bardet s findings. This condition has since become known as the Bardet Biedl syndrome . See also Bardet Biedl syndrome Persondata Metadata see Wikipedia Persondata . NAME Bardet, Georges ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 1885 PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Bardet, Georges Category French physicians Category 1885 births Category Year of death missing France med bio stub ... more details
Orphan date February 2009 Unreferenced date February 2007 A vestigial twin is a rare form of conjoined twin conjoined Siamese twinning or more accurately, of parasitic twin ning, where the parasitic twin is so malformed and incomplete that it typically consists of extra limbs or organs. The result is a person with &ndash for example, an extra arm or leg attached to him or her. This phenomenon occurs when a fertilized ovum or partially formed embryo splits. If the fetus splits completely, the result is two twin identical twins . However, if the fetus does not split fully, the result can be anything from two whole people joined by a bit of skin conjoined Siamese twins , through to one person with extra body parts the extra parts are the body of the vestigial twin. Most vestigial limbs are non functional, and although they may have bones, muscles and nerve endings, they are not under the control of the host. The possession of six or more digits on the hands and feet polydactyly usually has a Genetics genetic or chromosomal cause, and is not a case of vestigial twinning. Category Congenital disorders Category Twins ... more details
Majewski feminine Majewska is a Polish surname, it may refer to People Alicja Majewska , Polish singer Andrzej Majewski born 1966 , Polish aphorist, writer, columnist and photographer Gary Majewski born 1980 , baseball pitcher Janusz Majewski director , Polish film director Janusz Majewski fencer , Polish fencer Lech Majewski born 1953 , Polish American film and theatre director, writer, poet, and painter Malgosia Majewska , Polish Canadian model Neil Majewski born 1954 , Australian cricketer Rados aw Majewski born 1986 , Polish footballer Stefan Majewski born 1956 , Polish football player and football manager Szymon Majewski born 1967 , Polish journalist and entertainer Tomasz Majewski born 1981 , Polish shot putter Val Majewski born 1981 , baseball outfielder Other DPP v Majewski , English criminal law case Majewski s polydactyly syndrome , form of neonatal dwarfism dab Category Polish language surnames pl Majewski ... more details
with acheiropody and preaxial polydactyly , which likely result from altered sonic hedgehog ... citations cite journal author Hing AV, Helms C, Slaugh R, et al. title Linkage of preaxial polydactyly ... polydactyly with altered expression in limbs of Hemimelic extra toes mutant mice. journal Genomics ... cis acting regulator for Shh causes preaxial polydactyly. journal Proc. Natl. Acad. Sci. U.S.A. ... region is associated with preaxial polydactyly in humans and mice. journal J. Bone Miner. Metab. volume ... expression in the developing limb and fin and is associated with preaxial polydactyly. journal ... more details
appearance. This is considered an undesirable mutation. Polydactyly Polydactyl Polydactyl cat extra toed cat s. There are probably many genes, both dominant and recessive, that cause polydactyly in cats. Most cases of polydactyly in cats are perfectly harmless. Pd Thumb cat polydactyly gene. The Pd gene dominant with incomplete penetrance causes the benign, pre axial form of polydactyly where ..., this form of polydactyly is harmless. On the other hand, the hamburger feet polydactyly gene is associated ... source details. ref Mild RH can cause the post axial form of polydactyly enlarged paw s, extra three ... of polydactyly associated with RH. Polydactyl cats are relatively common in southwest Great Britain ... thumb s in the thumb cat form of polydactyly give them a survival advantage. Ernest ... more details
Image Polydactyly 01 Rhand AP.jpg thumb An x ray of a hand with a supernumerary digit polydactyly . Supernumerary body parts are most commonly a congenital disorder involving the growth of an additional part of the body and a deviation from the body plan . Body parts may be easily visible or hidden away, such as Organ anatomy internal organ s. Many additional body parts form by the same process as conjoined twins the zygote begins to split but fails to completely separate. This condition may also be a symptom of repeated occurrences of continuous inbreeding in a genetic line. It has been suggested that deliberately adding supernumerary limbs to humans may be possible, as a form of body modification . ref name DrJoeRosen http www.guardian.co.uk society 2002 mar 11 health.lifeandhealth I m having my wings done By Johann Hari. The Guardian, Monday 11 March 2002 ref Specific types of occurrence Specific types of additional body parts include Accessory breast one or more additional breast s ref name OMIM Online Mendelian Inheritance in Man. http www.ncbi.nlm.nih.gov entrez dispomim.cgi?id 163700 Nipples, Supernumerary . Accessed 10 July 2006. ref Cervical rib an additional rib ref PatientPlus. http www.patient.co.uk showdoc 40001959 Cervical ribs and thoracic outlet syndrome . Accessed 10 July 2006. ref Diphallia Having two penis penes penises . Hermaphrodite Hermaphroditism having both sexes sex organ s ref Grumbach, M.M., Conte, F.A., 1998. Disorders of sex differentiation. in Williams Textbook of Endocrinology, eds. J.D. Wilson, D.W. Foster, H.M. Kronenberg, and P.R. Larsen, Philadelphia W B Saunders 1303 1425 . ref ref Molnar, Sebastian, 17 February 2004. http web.archive.org web 20060210104030 http www.geocities.com we evolve Plants breeding sys.html Plant Reproductive Systems ... Pelvic digit a bony growth in the soft tissue of the pelvic region Polycephaly an extra head Polydactyly .... http pennstatehershey.adam.com content.aspx?productId 121 Polydactyly and Syndactyly . Accessed 10 ... more details
Context date October 2009 Unreferenced date May 2008 gallery Unsourced image removed Image Chromosome13.jpeg Depiction of Chromosome 13, where the abnormality is located. deletable image caption 1 subst time l, j F Y 7 days gallery Partial Monosomy of chromosome 13q, can be defined as the loss of or physical deletion of the long arm of chromosome 13 in human beings. This is a rare genetic disorder which can result in unusual abnormalities in which the sufferer most often dies at an improbable Ambiguous date July 2011 age. There are other symptoms, not limiting to the ones listed below. The chances of a subject being born with this disorder is very low. Symptoms Partial Monosomy of the Long Arm of Chromosome 13 is the deletion or tearing off of the end of the long arm of chromosome thirteen in humans. Problems Symptoms have been noted to be br Low birth weight br Malformations of the head br Abnormal eyes br Defects of the hands and feet, polydactyly br Reproductive abnormalities males br and largely, psychological and motor abilities are retarded. External Reading and Reference http www.bchealthguide.org kbase nord nord643.htm NORD Database, on BcHealthGuide.org DEFAULTSORT Partial Monosomy 13q Category Genetic disorders with no OMIM ... more details
in humans. PolydactylyPolydactyly from Greek many plus finger is when a limb has ... pentadactyl animal. Polydactyly is very common among domestic cats. For more information, see polydactyly . Polydactyly in early tetrapod aquatic animal s, such as Acanthostega gunnari Jarvik 1952 ... more details
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