cleanup date May 2011 Databases for oncogenomic research are biological databases dedicated to cancer data and oncogenomics oncogenomic research . They can be a primary source of cancer data, offer a certain level of analysis processed data or even offer online data mining . The table below gives an overview of databases for that serve specifically for oncogenomic research. Note that this is not a comprehensive list and does not contain databases that have a generic focus. You may find databases containg cancer data among the List of biological databases or Microarray databases . border 1 cellpadding 1 class wikitable sortable style width 100 font size 95 width 20 Database width 17 Institute Organization width 21 Alteration Types width 6 Primary Source ref group t The database is the publication site for some of its cancer raw data ref width 6 Processed Data ref group t The database contains cancer data at a certain level of analysis non raw data ref width 7 Organisms width 6 Cell lines ref group t The database also contains cell line data ref width 6 Public Data ref group t The database contains cancer data that is available for everyone ref width 6 Restricted Data ref group t The database contains cancer data that is only available under some restriction ref span id C span Cosmic cancer database Catalogue Of Somatic Mutations In Cancer COSMIC http www.sanger.ac.uk genetics CGP cosmic Wellcome Trust Sanger Institute , UK Mutation no yes Human no yes no span id C span cBio Cancer ... , Methylation , Gene Expression , miRNA Expression , Protein , Phosphorylation no yes Human ... Roche Diagnostics, Penzberg, Germany reflist group t See also Cancer Research List of biological databases Microarray databases Oncogenomics Oncology Notes references group note Category Applied genetics Category Bioinformatics Category Biological databases Category Medical genetics Category Cancer genome databases ... more details
IndexMaster Indian Railways Fan Club Inorganic Crystal Structure Database ICSD InTechOpen deadlink ... Matrix Y Yahoo Z Zabasearch.com Zillow.com ZINC database Zoho Creator See also List of academic databases and search engines List of biodiversity databases List of neuroscience databases References Reflist Category Online databases Category Internet related lists Databases ... more details
A number of online neuroscience databases are available which provide information regarding gene expression , neurons , macroscopic brain structure, and neurological or psychiatric disorders. While some databases contain descriptive and numerical data, others include postmortem brain sections or 3D MRI and fMRI images. A list that is regularly updated can be found at the http neuinfo.org nif nifgwt.html?query database&tab registry Neuroscience Information Framework database list , which contains over 2200 databases relevant to neuroscience. Try to add alphabetically to the table, or add to the other databases section and someone else will hopefully integrate it into the table. It is best if we have a small number of categories to the Data and Level section so ordering the table by this parameter is meaningful. Keep descriptions quite short Thanks class wikitable sortable style font size 85 text align center width auto style width 12em Name and External Link Description Organism Level gene, neuron, macroscopic Data MRI, fMRI, images, descriptive, numerical Disorder Register to view data? Ref Allen Brain Atlas http www.brain map.org Atlas, stained sections from brains showing development and gene expression Mouse, Human Macroscopic, Gene Images Healthy No ref Cite journal last Lein first Ed S. authorlink coauthors et al. year 2007 month title Genome wide atlas of gene expression in the adult mouse brain journal Nature journal Nature volume 445 issue 7124 pages 168 176 doi 10.1038 nature05453 url pmid 17151600 ref Alzheimer s Disease Neuroimaging Initiative ADNI http adni.loni.ucla.edu Structural MRI images Human Macroscopic MRI datasets Healthy and Alzheimer s Disease Yes ref cite journal doi 10.1002 jmri.21049 full last1 Jack first1 CR last2 Bernstein first2 MA last3 Fox ... No Other databases http www.birncommunity.org resources data BIRN fMRI and MRI data http fcon 1000.projects.nitrc.org ... Gateway References Reflist 2 DEFAULTSORT List Of Neuroscience Databases Category Biological databases ... more details
A supersecondary structure is a compact three dimensional proteinstructure of several adjacent elements of secondary structure that is smaller than a protein domain or a protein subunit subunit . Supersecondary structures can act as nucleation s in the process of protein folding . Examples include Beta hairpin hairpins , helix hairpins, and motifs. See also Structural motif Further reading cite journal author Chiang YS, Gelfand TI, Kister AE, Gelfand IM title New classification of supersecondary structures of sandwich like proteins uncovers strict patterns of strand assemblage. journal Proteins. volume 68 issue 4 pages 915 921 year 2007 pmid 17557333 doi 10.1002 prot.21473 DEFAULTSORT Supersecondary Structure Category Protein structural motifs ... more details
Orphan date February 2009 Glacio geological databases compile data on glacially associated sedimentary deposits and erosional activity from former and current ice sheets, usually from published peer reviewed sources. Their purposes are generally directed towards two ends Mode 1 compiling information about glacial landforms , which often inform about former ice flow directions and Mode 2 compiling information which dates the absence or presence of ice. These databases are used for a variety of purposes i as bibliographic tools for researchers ii as the quantitative basis of mapping of landforms or dates of ice presence absence and iii as quantitative databases which are used to constrain physically based mathematical models of ice sheets. Antarctic Ice Sheet The AGGDB is a Mode 2 glacio geological database for the Antarctic ice sheet using information from around 150 published sources, covering glacial activity mainly from the past 30000 years. It is available online, and aims to be comprehensive to the end of 2007. ref http www.antarctica.ac.uk met rcah agdb index.htm Database main page Bot generated title ref British Ice Sheet BRITICE is a Mode 1 database which aims to map all glacial landforms of Great Britain. ref http www.sheffield.ac.uk geography staff clark chris britice.html Clark, Chris Bot generated title ref Eurasian Ice Sheet DATED 1 is a Mode 2 database for the Eurasian ice sheet. Its sister project DATED 2 uses the information in DATED 1 to map the retreat of the Eurasian ice sheet since the Last Glacial Maximum . ref http www.gyllencreutz.se research.html R i c h a r d G y l l e n c r e u t z Bot generated title ref See also Glacial landforms Sediment Geology Ice sheet Exposure Age Dating Radio carbon dating References reflist Category Quaternary Category Physical geography Category Physical oceanography Category Scientific databases ... more details
Protein database may refer to Any proteinstructure database Any protein sequence database Exact names Protein NIH Protein database of the National Institute of Health Protein Database of Bio Synthesis, Inc. disambig ... more details
The China Economic Databases CED zh c is a project of the China Studies Center at National Chengchi University , Taiwan . It collects and publishes information on China s Economy of the People s Republic of China economic economic development development to support scholarly research. The CED is available in Chinese language Chinese and English language English . Mission The CED is designed for scholars, students and those interested in the study and development of the economy of the People s Republic of China . Anyone is able to add information to the platform by submitting relevant material. History The CED is sponsored by the Center for China Studies in National Chengchi University , in Taiwan , and is supported by the Taiwan Ministry of Education. The project was launched in December 2003 and is currently directed by Dr. Chen yuan Tung , a Professor at the Graduate Institute of Development Studies, National Chengchi University. Databases Currently there are ten databases 1. China Economic Literature Index Database The China Economic Literature Database CELD currently collects data from 47 Chinese periodicals and 22 English sources. Additionally, online databases such as SSCI and EconLit are used to keep the database up to date. Information in the CELD range in topics including macroeconomics, capital investment, regional development, economical reform, trade between Taiwan and Mainland China, Chinese foreign trade, Renminbi exchange, economical globalization, financial ... databases of the China Economic Databases platform. 10. The OpenCourseWare OCW Project gathers ... publications of the bi weekly China Economic Databases E paper are available online. The E paper ... links http ics.nccu.edu.tw eced China Economic Databases Website The official CED site http ics.nccu.edu.tw eced eocw China s Economy OCW The OpenCourseWare project of the China Economic Databases Category Economic databases Category Economy of the People s Republic of China Category Databases in Taiwan ... more details
This is a list of biodiversity databases . Biodiversity databases store taxonomy taxonomic information which provide information on the biodiversity of a particular area or group of living organisms. They may store specimen level information, species level information, information on nomenclature, or any combination of the above. Most are available online. Specimen focused databases contain data about individual specimens, as represented by vouchered museum specimens, collections of specimen photographs, data on field based specimen observations and morphological or genetic data. Species focused databases contain information summarised at the species level. Some species focused databases attempt to compile comprehensive data about particular species FishBase , while others focus on particular species attributes, such as checklists of species in a given area FEOW or the conservation status of species CITES or IUCN Red List . Nomenclators act as summaries of taxonomic revisions and set a key between specimen focused and species focused databases. They do this because taxonomic revisions use specimen data to determine species limits. class wikitable sortable Name Focus Collection All Catfish Species Inventory ref cite web url http silurus.acnatsci.org title All Catfish Species Inventory accessdate 2010 06 04 ref Catfish information collated by genera, including estimated numbers of species, taxonomic experts Arctos ref cite web url http arctos.database.museum title Arctos accessdate 2011 06 09 ref Specimen holdings of several natural history museums, agencies, and accessible private collections Vertebrates, invertebrates, parasites, vascular and non vascular plants, many with images and extensive usage data. AntWeb ref cite web url http www.antweb.org title AntWeb author date work publisher accessdate 2010 06 04 ref Ant s Specimen information, collection details ... Category Biological databases ... more details
Merge List of genealogy portals date March 2010 This is a list of genealogy databases and online resources that are not specifically restricted to a particular place, family set, or time period in their content. Dynamic list FamilySearch a database developed by The Church of Jesus Christ of Latter day Saints . GEDCOMP automated, free GEDCOM COMParison mostly related to Denmark . ref cite news date 2004 04 22 accessdate 2009 01 14 url http query.nytimes.com gst fullpage.html?res 9807E3D8163AF931A15757C0A9629C8B63&sec &spon &pagewanted print title From Shared Resources, Your Personal History author Peter Wayner work The New York Times ref GeneaNet an international genealogy database. Hindu genealogy registers at Haridwar , India , microfilmed at the Genealogical Society of Utah GSU , USA. MyHeritage research, an aggregated search system covering a large number of genealogy databases. Rodovid global genealogy, over 19 languages. Serbian Genealogical Society Contains a online database with surnames, locations and background information. Limited access for unregistered users. SortedByName millions of entries from transcription projects, sorted alphabetically and by Soundex, with links to their respective transcription project sites. Werelate.org large genealogy wiki, supporting sourced collaborative. With wiki pages for over 2 million persons, 700,000 families. Sponsored by the Allen County Public Library and the Foundation for On Line Genealogy. Also hosts the largest genealogical referenced place index with over 400,000 wiki pages and a genealogical source index with almost one million wiki pages. Comparison of notable databases for uploading family trees Some of these also have social network ing features. class sortable wikitable Web site Alexa Internet Alexa traffic rank ref name Alexa Traffic rank according to http www.alexa.com siteinfo ancestry.com rodovid.org familysearch.org ... databases de Genealogie Datenbank ... more details
Orphan date February 2009 Restricting access to production databases is a requirement of Sarbanes Oxley Act sections 302, 404, and is included in the COBIT framework. Restricting access Steps to restrict database access within an organization Implement Separation of duties SOD a preventive control. Establish test and production environments which is preventive control. Restrict user account and Database administrator access which is a preventive control. Turn on audit trails, monitoring software, or exception reports which are detective controls. Elements to restrict include br Data access Successful Failed Selects Data Changes Insert, Update, Delete System Access Successful Failed Logins User Role Permissions Password changes Privileged User Activity All Schema Changes Create Drop Alter Tables, Columns, Fields Controls Compensating Controls Exploiting technology known as triggers. Triggers are user written code, or DBA written code, that gets inserted into the database and gets executed whenever an insert or an update or a delete occurs. br Cons br a. Transaction performance could suffer. br b. This solution does not provide 100 assurances of an incorruptible audit trail. br c. Triggers can be modified by anyone who has the appropriate privileges. Implement application based auditing. br Con br Effective only if no other application or utility can access the database s . Perform auditing on a per database, per table, per column, or per user basis. br Con br Labor intensive for IT. Would require a manual review the audit report and verify before after what was changed and sign off that the change was authorized and acceptable. Control evaluation considerations by Internal Audit The overall control evaluation cannot be determined until after the compensating controls have .... The best control environment surrounding databases is to have the ability to track and review, any and all adds, deletes and modifications to the databases. Deficiency Deficiency and Material Weakness ... more details
This is a list of online database s that publish funding opportunity funding opportunities . http australiangovernmentgrants.org wizard.php Australian Government Grants Australian Directory of Philanthropy , Philanthropy Australia Community of Science Funding Opportunities Dialog OnDisc Grants Database , Dialog OnDisc FC Search , Foundation Center , replaced by Foundation Directory Online Federal Assistance Program Retrieval System FAPRS Federal Information Exchange FEDIX , merged with RAMS Federal Research in Progress FEDRIP , National Technical Information Service grants.gov , US Federal Government Funding Opportunities GrantSelect GrantScape , Catalog of Federal Domestic Assistance GrantSelect , American Association of State Colleges and Universities Illinois Researcher Information Service IRIS Research Professional , Research Limited http www.researchresearch.com professional http www.researchresearch.com professional SciVal Funding , Elsevier Sponsored Programs Information Network SPIN , InfoEd The Funding Portal, Search Engine for Canadian Public Funding Opportunities http www.thefundingportal.com www.thefundingportal.com World Academy of Young Scientists http www.waysnet.org wiki index.php?title Searching for Funds Searching for Funds http www.waysnet.org wiki index.php?title List of funding bodies List of funding bodies http www.ors.duke.edu find tools index.html Funding Search Tools at Duke University http foundationcenter.org findfunders Resources at http foundationcenter.org Category Research Category Online databases zh ... more details
wiktionary structure The structure of a thing is how the parts of it relate to each other, how it is assembled . Structure may also refer to Architectural structure , a man made structure used or intended for supporting or sheltering any use or continuous occupancy Building , Non building structure & Building disambiguation Canopy ecology structure, organization or three dimensional geometry of a plant canopy Community ecology structure, ecological organization of a biological community Chemical structure , the spatial arrangement of atoms and bonds in a molecule Proteinstructure Crystal structure , structure of liquids and glasses , the spatial arrangement of ions, atoms, or molecules in condensed matter Data structure , a way of storing data in a computer so that it can be used efficiently Mathematical structure on a set, additional mathematical objects that in some manner attach to the set, making it easier to visualize or work with, or endowing the collection with meaning or significance Structure mathematical logic Algebraic structure Social structure , a pattern of relations Structure and agency , two confronted theories about human behaviour Structural geology , the three dimensional distribution of rock bodies and their planar or folded surfaces, and their internal fabrics Deep structure logical language structure in linguistics The Structure of Scientific Revolutions , a book by Thomas Kuhn on the history of science Structure journal , a scientific journal describing proteinstructure s Large scale structure of the cosmos Capital structure Financial structure , a cocept within structured finance Structure, the former name for the Express Men clothing brand Structures Structures Boulez , composition Structures album , by John Digweed Structures from Silence , album by Steve Roach Structures of Death , album by Fleshcrawl See also Struct disambiguation disambig ar br Framm da Struktur flertydig fr Structure gl Estrutura it Struttura hu Strukt ra egy rtelm s t ... more details
, food, and forestry around Oklahoma. Below are a number of databases to search for vital statistics ... connections to the Department home page and various online databases. http odol agent.auto ... ada OESC Job Search Category Online databases Category Government databases ... more details
the heat content . Different databases designate this term in different ways for example H sub T sub ... thermodynamic databases such as for steam, the reference temperature is 273.15 K 0 C . The Heat capacity ... of thermochemical databases may contain some additional thermodynamic functions. For example ... databases A thermodynamic database consists of sets of critically evaluated values for the major thermodynamic ... equations that could be used to reproduce the tabular values. More recently, computerized databases ... at any temperature and prepare tables for printing. Computerized databases often include subroutines ... for the equation. Most computerized databases will create a table of thermodynamic values using the values ... data. http www.thermodata.org THERMODATA Thermochemical Databases and Software. http www.aiche.org ... design and equilibrium calculations. http www.mtdata software.com MTDATA software and databases for calculation ... Steam Tables Online calculator based on IAPWS IF97 Category Thermodynamics Category Scientific databases ... more details
This is a list of online music databases , as well as including a list of sites that currently provide free and paid for on demand music as a streaming media . A primary unit of many of these two types of sites is the Song track s which is often referred to in the marketplace simply as a song. DO NOT ADD NEW ENTRIES THAT DON T ALREADY HAVE ASSOCIATED ARTICLES. Alternatively, you should provide evidence of notability on the talk page, or in your edit summary see http en.wikipedia.org wiki Wikipedia Notability Online music databases Below is a table of online music databases that are largely free of charge. Note that many of the sites provide a specialized service or focus on a particular music genre. Some of these operate as an online music store or purchase referral service in some capacity. Among the sites that have information on the largest number of entities are those sites that focus on discographies of composing and performing artists. class wikitable sortable Database Services No. of tracks No. of releases No. of artists Notes License Full free access Albumography Database of information, ratings, and reviews for artists, albums, and songs Yes Allmusic Music information and reviews 20,000,000 ref name allmusic cite web title Coverage Statistics publisher allmusic url Allmusic class about id pure url yes accessdate 2011 06 12 ref 2,200,000 ref name allmusic Song samples only BestEverAlbums.com Database and community 180,000 ref name BEA cite web title BestEverAlbums.com Statistics publisher BestEverAlbums.com url http www.besteveralbums.com howitworks.php accessdate 2010 07 28 ref 15,000 ref name BEA 7,000 ref name BEA Song samples only Choral Public Domain Library TimeTrippinRadio.com Online Radio Station, Music Database and Community, featuring information, ratings, and reviews for artists, albums, and songs in Blues, Jazz, Gospel, R&B Soul, and Southern Soul genres ... databases Category Online content distribution Music es Anexo Bases de datos en l nea de m sica ... more details
italictitle Infobox journal title Structure cover editor Christopher D. Lima and Andrej Sali discipline Proteinstructure abbreviation Structure publisher Cell Press country United States frequency 12 year history 1993 present openaccess license impact impact year website http www.cell.com structure home link1 http www.cell.com structure archive link1 name Archives link2 link2 name RSS atom JSTOR OCLC 28867361 LCCN CODEN ISSN 0969 2126 eISSN boxwidth Structure is a peer review ed scientific journal founded by Wayne A. Hendrickson , Carl Ivar Br nd n and Alan R. Fersht in September 1993. It focuses on proteinstructure and related issues. The journal is published monthly by Cell Press . The current editors are Christopher D. Lima and Andrej Sali . Reed Elsevier journal stub Category Biochemistry journals Category Cell Press academic journals Category Publications established in 1993 ... more details
structure prediction software http openwetware.org wiki Proteinprotein interaction databases Overview of protein interaction databases Servers http 3d partner.life.nctu.edu.tw vers pub index.php 3D ... a known structure i.e. present in the Protein Data Bank PDB . Bayesian network modelling Bayesian ... Prediction of proteinprotein interactions by combining structure and sequence conservation in protein .... Russell. 2003 InterPreTS protein Interaction Prediction through Tertiary Structure . Bioinformatics ... to make use of the DNA sequence, protein sequence s must be predicted and verified, Proteinstructure ... to avoid or minimise computation of dynamics Folding and Docking The most effective Proteinstructure ... s on a single folded proteinstructure and match them to active sites on a second protein using ... Protein Interfaces. Proteins Structure, Function and Bioinformatics., 64, 344 355. Kim, Wan Kyu ... Protein interactions Proteinprotein docking Structural Bioinformatics Proteinstructure Structural ...Proteinprotein interaction prediction is a field combining bioinformatics and structural biology in an attempt ... proteinprotein interaction s is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical ... of experimental techniques, including yeast two hybrid screening two hybrid systems, protein fragment complementation assays PCA , affinity purification mass spectrometry , protein microarray s, fluorescence ... in other organisms. In addition, a number of bound protein complexes have been structurally solved ... pairs of protein families with similar patterns of presence or absence across large numbers of species ... imply physical interaction. Prediction of co evolved protein pairs based on similar phylogenetic ... protein in the hypothesized interacting pair. If the matrices are sufficiently similar as measured .... The identification of the domains is done by sequence searches against domain databases such as Pfam ... more details
The Unisys OS 2200 operating system OS 2200 database managers are all part of the Universal Data System UDS . UDS provides a common control structure for multiple different data models. Flat files sequential, multi keyed indexed sequential MSAM, and fixed block ref Unisys Corporation 1997 . u Shared File System SFS 2200 Administration and Support Reference Manual u . Unisys publication 7831 0786 . Roseville, MN. http public.support.unisys.com 2200 docs cp12.0 pdf 78310786 002.pdf ref , Network model network DMS ref Unisys Corporation 1999 . u Data Management System DMS 2200 Schema Data Definition Language DDL Administration, Operations, and Programming Guide u . Unisys publication 7831 0745 . Roseville, MN. http public.support.unisys.com 2200 docs cp12.0 pdf 78310745 004.pdf ref , and Relational database relational RDMS ref Unisys Corporation 1998 . u Relational Data Management System RDMS 2200 and IPF SQL Interface End Use Guide u . Unisys publication 7831 0778 . Roseville, MN. http public.support.unisys.com 2200 docs cp12.0 pdf 78310778 002.pdf ref data models all share a common locking, recovery, and clustering mechanism. OS 2200 applications can use any mixtures of these data models along with the high volume transaction file system ref Unisys Corporation 1995 . u Transaction Processing Conceptual Overview u . Unisys publication 7830 9960 . Roseville, MN. http public.support.unisys.com 2200 docs cp12.0 pdf 78309960 003.pdf ref within the same program while retaining a single common recovery mechanism. ref Unisys Corporation 2009 . u Universal Data System Administration and Support Reference Manual u . Unisys publication 7831 0737 . Roseville, MN. http public.support.unisys.com 2200 docs cp12.0 pdf 78310737 017.pdf ref File OS 2200 Database Architecture.jpg center The database managers are implemented as a Unisys OS 2200 operating system Subsystems protected subsystem and are called as a procedure from user programs and other subsystems. The implementation as a s ... more details
Biomolecular structure is the structure of biomolecule s, mainly protein s and the nucleic acid s DNA and RNA . The structure of these molecules is frequently decomposed into primary structure, secondary structure, tertiary structure, and quaternary structure. The scaffold for this structure is provided ... recognizable domains of proteinstructure and nucleic acid structure , including secondary structure ... . Primary structure Main Protein primary structure Nucleic acid primary structure In biochemistry , the Primary structure of a biological molecule is the exact specification of its atomic composition ... sequence. By convention, the primary structure of a protein is reported starting from the amino terminal ... doi 10.1016 0092 8674 81 90522 5 ref Secondary structure Main Protein secondary structure Nucleic ... assign its secondary structure by eye and record their assignments in the corresponding Protein ... structure prediction software . Tertiary structure Main Protein tertiary structure Nucleic acid tertiary structure In biochemistry and molecular biology , the tertiary structure of a protein or any other ... Main Protein quaternary structure Nucleic acid quaternary structure In biochemistry , quaternary structure is the arrangement of multiple protein folding folded protein or coiling protein molecules ... issue 9 pages 4899 903 ref or spliceosome . Structure determination Main Proteinstructure determination ... and the structure distances computed using RNAdistance. Main Proteinstructure prediction Nucleic ... structure of a protein from its amino acid sequence, or of a nucleic acid from its Nucleobase ... structure. Structure prediction is the inverse of biomolecular design. Proteinstructure prediction ... and beta sheet s for proteins. The terms primary, secondary, tertiary, and quaternary structure were ..., un crosslinked biopolymer such as a molecule of DNA , RNA or typical intracellular protein , the primary structure is equivalent to specifying the sequence of its monomer ic subunits, e.g., the nucleotide ... more details
italictitle Infobox journal title Protein Science cover File Protein Science Cover low res.gif editor Brian Matthews biochemist Brian W. Matthews discipline Biochemistry peer reviewed Yes language English language English abbreviation Protein Sci. publisher Wiley Blackwell publisher Wiley Blackwell country United States frequency 12 year history 1992 present openaccess Delayed license impact 3.115 impact year 2008 website http www.proteinscience.org link1 link1 name link2 link2 name RSS http www.proteinscience.org rss current.xml atom JSTOR OCLC 25450084 LCCN 92660027 CODEN PRCIEI ISSN 0961 8368 ISSN2 1359 5040 eISSN 1469 896X boxwidth Protein Science is a Peer review peer reviewed scientific journal publishing research on the structure, function, and biochemical significance of proteins, their role in molecular biology molecular and cell biology , genetics , and evolution , and their regulation and mechanisms of action. It is published by Wiley Blackwell publisher Wiley Blackwell on behalf of The Protein Society . Abstracting, archiving, indexing Since January 2008, published articles are deposited in PubMed Central with a 12 month embargo. ref cite web title PubMed Central New Journals Participating and New Content Added url http www.nlm.nih.gov pubs techbull jf08 jf08 pmc.html ref Protein Science is indexed and or abstracted in the following databases and publications MEDLINE , Science Citation Index , and Scopus . External links http www.proteinscience.org Journal homepage http www.pubmedcentral.nih.gov tocrender.fcgi?journal 507&action archive Archives of Protein Science at PubMedCentral References references Category Publications established in 1992 Category Biochemistry journals Category Wiley Blackwell academic journals biology journal stub ... more details
Image Structure validation concept.jpg thumb right Structure validation concept model of a protein each ... parameters for X ray proteinstructure refinement journal Acta Crystallographica volume A 47 pages ... PSVS ProteinStructure Validation Server at the NESG http code.google.com p cing CING Common Interface ... Macromolecular structure validation is the process of evaluating reliability for 3 dimensional atomic ... from the atomic model. For a well determined small molecule structure the R factor is nearly as small ... by automated software ref Cite journal author Spek AL year 2003 title Single crystal structure ... S0021889802022112 ref as a requirement for small molecule crystal structure papers submitted to the International ... quality of protein structures journal J. Applied Crystallography volume 26 pages 283 291 ... in protein structures journal Nature London volume 381 pages 272 ref . For macromolecular structures, the atomic models are deposited in the Protein Data Bank PDB , still the single archive of this data ... , Shimanouchi T, Tasumi M year 1977 title The Protein Data Bank A computer based archival file for macromolecular ... H, Shindyalov IN, Philip Bourne Bourne PE year 2000 title The Protein Data Bank journal Nucleic Acids ... worldwide Protein Data Bank ref name wwPDB cite journal author Helen M. Berman Berman HM , Henrick K, Nakamura H year 2003 title Announcing the worldwide Protein Data Bank journal Nature Structural ... GJ year 2000 title Validation of protein crystal structures journal Acta Crystallogr volume D 56 pages ..., when the worldwide Protein Data Bank wwPDB made mandatory the deposition of experimental data along ..., Vriend G, Zwart PH year 2003 title A New Generation of Crystallographic Validation Tools for the Protein Data Bank journal Structure volume 19 pages 1395 1412 PMID 22000512 doi 10.1016 j.str.2011.08.006 ... evaluation criteria apply globally to an entire experimental structure, most notably the Resolution ... among related Protein Data Bank entries to answer their questions. Other criteria apply to individual ... more details
proteins with known 3D structure to different membrane types ref Membrane protein complexes Membrane ... occurs creating its final 3D structure White . Non constitutive membrane protein Examples of non ... http memprotein.org Membrane Protein Structural Dynamics Consortium Membrane proteindatabases http ...Image 2r9r opm.gif thumb 300px Crystal structure of Potassium channel KvAP. Calculated hydrocarbon boundaries of the lipid bilayer are indicated by red and blue dots. A membrane protein is a protein molecule ... biological functions. Protein Structural proteins Structural protein s are attached to microfilament .... Membrane transport protein Transport protein s play an important role in the maintenance of concentrations of ion s. These transport proteins come in two forms carrier protein s and channel protein ... bilayer or with integral membrane proteins Lipid anchored protein s bound to lipid bilayer bound ... states a water soluble and a lipid bilayer bound. The amphitropic protein category includes .... Integral membrane proteins Integral membrane protein s are permanently attached to the membrane. They can ... with the bilayer Integral polytopic protein s, also known as transmembrane proteins ... bacteria , and outer membranes of mitochondria and chloroplasts . Integral monotopic protein s are proteins ... protein s are temporarily attached either to the lipid bilayer or to integral proteins by a combination ... their function and regulation. Reoccurring in recent literature are the ideas that membrane protein ..., and membrane proteins can be interchanged in existing complexes. Membrane protein complexes ... preventing damaging interactions they could cause. Membrane protein complexes are not fixed entities ... protein complexes. This has its implications as a repair mechanism and in regulation. ref Daley, Daniel ..., 18 420 424. ref Assembly of membrane protein There are two different types of membrane proteins depending upon the synthesis it undergoes and they are Constitutive membrane protein and non constitutive ... more details
Dodecameric is a term pertaining to protein quaternary structure , and describes a protein complex with 12 protein subunits protein chain s . Dodecameric complexes can have a number of Protein subunit subunit topology topologies , but typically only a few of the theory theoretically possible subunit arrangement s are observed in proteinstructure s. A dodecamer is a protein complex with 12 protein subunits. A common Protein subunit subunit arrangement involves a tetrahedral distribution of subunit protein trimer trimer s or 3 4 Point groups in three dimensions point symmetry . Another observed arrangement of Protein subunit subunits puts two rings of six subunits side by side along the six fold axis or 2 6 point symmetry . Dodecameric proteins include Complete gap junction channel, composed of two hexamers. glutamine synthetase PDB code http www.pdbe.org 2gls 2gls Dodecameric ferritin PDB code http www.pdbe.org 1qgh 1qgh A 42 Amyloid beta 42 References Protein Data Bank The Protein Data Bank PDB http www.pdbe.org pisa Protein Interfaces, Surfaces and Assemblies Server PISA part of the http www.pdbe.org PDBe . Category Proteinstructure biochem stub ... more details
A chemical structure includes molecular geometry , electronic structure and crystal structure of molecule s. Molecular geometry refers to the spatial arrangement of atom s in a molecule and the chemical bond s that hold the atoms together. Molecular geometry can range from the very simple, such as diatomic oxygen or nitrogen molecules, to the very complex, such as protein or DNA molecules. Molecular geometry can be roughly represented using a structural formula . Electronic structure describes the occupation of a molecule s molecular orbital s. The theory of chemical structure was first developed by Aleksandr Butlerov , which stated that the chemical compounds are not a random cluster of atoms and functional groups but structures with definite order formed according the valency chemistry valency of the composing atoms . Structure determination Structural determination in chemistry is the process of determining the chemical structure of molecules. Practically, the end result of such process is the obtainment of the coordinates of the atoms in a molecule. ref name lecture07uwec http www.chem.uwec.edu Chem406 F06 Pages lecture notes lect07 C406 lect07 notes.pdf C406 lect07 Bot generated title PDF, 936 KiB ref The methods by which one can determine the structure of a molecule include spectroscopy , such as nuclear magnetic resonance NMR , infrared spectroscopy and Raman spectroscopy , electron microscopy , and x ray crystallography x ray diffraction . The last technique can produce three dimensional models at atomic scale optical resolution resolution , as long as crystal s are available ... the chemical structure Structural elucidation X ray diffraction Proton NMR Carbon 13 NMR Mass spectrometry Infrared spectroscopy The following are common methods for determining the electronic structure ... of drugs QSAR , quantitative structure affinity relationship Chemical property Molecular property ... es Estructura qu mica fr Structure chimique he nl Chemische structuur ja nds Cheemsch ... more details
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