Wiktionary amphetamine Amphetamine is a psychostimulant drug. Amphetamine may also refer to Amphetamine film Amphetamine film , a 2010 Hong Kong film Substituted amphetamine , a chemical class of stimulants, entactogens, hallucinogens, and other drugs Amphetamine Reptile Records , an American record label disambiguation zh ... more details
wiktionary meth Meth or meths may refer to Methamphetamine , a psychostimulant stimulant drug Methanol , a simple alcohol with formula CH sub 3 sub OH Methylated spirit , ethanol that has additives to make it more poisonous or unpalatable Methadone , a synthetic opioid Meth , a prefix for methyl group organic chemicals Method Man , American hip hop artist Meth film Meth film , a documentary on drug abuse among gay men Meth album Meth album , by rapper Z Ro disambig ... more details
wiktionary greenie Greenie may refer to Greenie Australian bird , an Australian lorikeet Greenie Scottish bird , the European Greenfinch Greenie drug , a psychostimulant drug of the phenethylamine class Greenie occupation , one who broadly supports the goals of the environmental movement Greenie occupation , a member of the Royal Australian Navy, who is an Electronics Technician Greenie Bus , the shuttle buses that operate in the University Circle area of Cleveland, Ohio The Greenies , an episode of the TV series The Goodies La Salle Greenies , the varsity team representing La Salle Green Hills See also Greaney disambiguation Greany Building , a historic building in Fall River, Massachusetts Green disambiguation Norm Greeney , American football player disambiguation ... more details
unreferenced date December 2009 In pharmacology , a psychoanaleptic is a medication that produces an arousing effect . Antidepressant s, psychostimulant s, Anti ADHD agent agents used for ADHD and nootropic s, and Anti dementia drug s are all psychoanaleptics. The psychoanaleptics are classified under ATC code N06 N06 in the Anatomical Therapeutic Chemical Classification System . See also Psycholeptic External links http medical dictionary.thefreedictionary.com psychoanaleptic Major drug groups Antidepressants Psychostimulants, agents used for ADHD and nootropics Anti dementia drugs Category Psychoanaleptics nervous system drug stub et Ps hhoanaleptilised ained eu Psikoanaleptiko fr Psychoanaleptique ru sv Psykoanaleptika ... more details
Drugbox verifiedrevid 424969309 IUPAC name N isopropyl 1 phenylpropan 2 amine image Isopropylamphetamine.svg Clinical data tradename Identifiers CAS number ATC prefix none ATC suffix PubChem 213536 Chemical data C 12 H 19 N 1 molecular weight 177.286 g mol synonyms N isopropylamphetamine Isopropylamphetamine is a psychostimulant of the substituted phenethylamine phenethylamine and substituted amphetamine amphetamine chemical class es. It is an isomer of propylamphetamine . See also Amphetamine Ethylamphetamine Isoprenaline Methamphetamine Propylamphetamine References Reflist 2 Unreferenced date August 2009 Stimulants Adrenergics Dopaminergics Phenethylamines Category Amphetamines nervous system drug stub ... more details
orphan date March 2010 Drugbox verifiedrevid 411246460 image width 100px drug name Obetrol Combo data type combo component1 Dextroamphetamine class1 Psychostimulant component2 Amphetamine class2 Psychostimulant component3 Methamphetamine class3 Psychostimulant Clinical data tradename licence US FDA may use generic name pregnancy US C legal US Schedule II dependency liability High routes of administration Oral Chemical data Obetrol is a pharmaceutical stimulant, amphetamine, used as an anorexiant to treat exogenous obesity with racemic amphetamine and methamphetamine salts. Obetrol was a stimulant based diet pill popular in the 1950s and 1960s. ref name Real Obetrol Ad cite news first Nicolas last Rasmussen coauthors authorlink title On Speed The Many Lives of Amphetamine date 2008 03 01 publisher New York University Press url http hist phil.arts.unsw.edu.au staff staff.php?first Nicolas&last Rasmussen work pages 148 Fig. 33 accessdate 2009 01 27 language ref Partial Misconception There is a misconception among some that the ingredients in the drug Obetrol have always been the same as those in the present day drug Adderall . In fact, the drug Obetrol was reformulated at least once. A look at the history of the drug and its manufacturer s may help to clarify this. In the 1950s, Obetrol was manufactured by Obetrol Pharmaceuticals, in Brooklyn, New York. The Company later became a Division of Rexar Pharmacal Corporation, which was also headquartered in Brooklyn. Sometime prior to 1972, Rexar Pharmacal moved its manufacturing facilities, including its Obetrol Pharmaceutical Division, to Valley Stream, New York. By the 1990s, Obetrol Pharmaceuticals had been wholly absorbed by Rexar Pharmacal, and was no longer noted as a division of Rexar. Per the 1972 Physicians Desk Reference, Obetrol contained per 10 mg tablet 2.5 mg methamphetamine saccharate 2.5 mg methamphetamine hydrochloride 2.5 mg racemic amphetamine sulfate 2.5 mg dextroamphetamine sulf ... more details
From MoS DAB use ONE LINK per entry and SHORT descriptions. AVOID piping, external links, red links with little potential. wikt dex Dex may refer to DEX Graph database DEX is a graph database. In astronomy, a contraction of decimal exponent , for use with values on a Logarithm log sub 10 sub scale Acronym for Dexterity in Role playing game role playing games Dexamethasone , a potent synthetic member of the glucocorticoid class of steroid hormones Enantiomer Dextrorotary stereoisomer , in chemistry Dextrorotation , the property of clockwise rotating plane polarized light Dextromethorphan , an antitussive drug Dextroamphetamine , a psychostimulant drug Dexmedetomidine , a sedative medication frequently used in the ICU A nickname for the name Dexter disambiguation Dexter DEX 15 , a computer operating system A fictional character from the film Star Wars Episode II Attack of the Clones The lead character in the film The Tao of Steve Dex, the official directory of Qwest Communications International Dex Media Dex One Barbara Dex .dex , standard extension for a Dalvik Executable File, which programs for the Android OS are compiled into disambig de Dex zh DEX ... more details
File Blue Crystal Meth .jpg thumb 250px Methamphetamine Methamphetamine s ability to release dopamine rapidly in Reward system reward regions of the brain produces a rush as forerunner to the high experienced with the use of methamphetamine that many users feel after Insufflation medicine snorting , smoking, or Drug injection injecting the drug. ref http drugabuse.gov infofacts methamphetamine.html Methamphetamine InfoFacts The National Institute on Drug Abuse NIDA ref In psychology , a rush is an Wiktionary acute acute Wiktionary transcendent transcendent state of euphoria . Psychoactive drug s which enhance dopaminergic neurotransmission in the central nervous system CNS are commonly capable of such an event. These drugs include opiates and opioids , such as heroin and morphine , and psychostimulant s, such as methamphetamine and cocaine . Studies have shown that the subjective pleasure of drug use the reinforcing component of addiction is proportional to the rate at which the blood level of the drug increases. ref http jpet.aspetjournals.org content 301 2 690.full.pdf Onset of Action and Drug Reinforcement ref Intravenous injection is the fastest route of administration, causing blood concentrations to rise the most quickly, followed by smoking, suppository anal or vaginal insertion , Insufflation medicine insufflation snorting , and ingestion swallowing . Ingestion does not produce a rush. ref http www.abstemious.org Meth.htm Methamphetamine Abstemious Outpatient Clinic, Inc. ref See also Dopamine Reward system References Reflist 2 Emotion footer Category Happiness Category Addiction psychiatry Category Psychoactive drugs psych stub Wiktionary rush Etymology 2 ... more details
Drugbox IUPAC name 1,3,7 trimethyl 8 2 methyl 1 phenylpropan 2 yl amino ethyl amino 3,7 dihydro 1 H purine 2,6 dione image Fencamine.png Clinical data tradename pregnancy category legal status Rx only routes of administration Mouth Oral Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number 28947 50 4 ATC prefix none ATC suffix PubChem 115374 ChemSpiderID 103208 Chemical data C 20 H 28 N 6 O 2 molecular weight 384.48 g mol smiles O C2N c1nc n c1C O N2C C NCCN C C Cc3ccccc3 C C Fencamine Altimina , Sicoclor is a psychostimulant drug of the substituted amphetamine amphetamine class. It is closely related to fenethylline . ref name pmid12024689 cite journal author Cody JT title Precursor medications as a source of methamphetamine and or amphetamine positive drug testing results journal Journal of Occupational and Environmental Medicine American College of Occupational and Environmental Medicine volume 44 issue 5 pages 435 50 year 2002 month May pmid 12024689 doi url ref References Reflist Stimulants Adrenergics Dopaminergics Phenethylamines Category Amphetamines Category Norepinephrine dopamine reuptake inhibitors Category Xanthines ... more details
Drugbox IUPAC name 2 phenyl 3 methyl morpholin 5 one image Fenmetramide.png Clinical data tradename pregnancy category legal status routes of administration Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number 5588 29 4 ATC prefix None ATC suffix PubChem 21789 ChemSpiderID 20479 UNII Ref fdacite correct FDA UNII WCH9HW127L KEGG D04153 Chemical data C 11 H 13 N 1 O 2 molecular weight 191.23 g mol smiles O C1NC C OC1 c2ccccc2 C Fenmetramide is a drug which was patented as an antidepressant by McNeil in the 1960s. ref US Patent 3308121 3 MORPHOLINONES, THIONES & 5,6 OXAZINES ref The drug was never marketed. ref name isbn0 412 46630 9 cite book author David J. Triggle title Dictionary of pharmacological agents publisher Chapman & Hall location London year 1997 pages isbn 0 412 46630 9 oclc doi url http books.google.com books?id A0THacd46ZsC&lpg PA1333&dq fenmetramide&pg PA1333 v onepage&q fenmetramide&f false ref It is the 5 ketone chemical derivative derivative of phenmetrazine and would similarly be expected to produce psychostimulant effects, though pharmacology pharmacological data is lacking. See also Fenbutrazate Phendimetrazine Phenmetrazine References Reflist Antidepressants Stimulants Category Antidepressants Category Ketones Category Morpholines Category Stimulants ... more details
Drugbox IUPAC name 2 amino 1,1 diphenyl 1 heptanol image Hexapradol structure.png CAS number 15599 37 8 CAS supplemental br ATC prefix None ATC suffix PubChem 219120 ChemSpiderID 189933 chemical formula C sub 19 sub H sub 25 sub NO molecular weight 283.408 g mol smiles OC c1ccccc1 c2ccccc2 C N CCCCC synonyms small butyl hydroxy phenylamphetamine small br small pentyl hydroxy phenyl 2 phenethylamine small br small phenyl 2 phenylheptanolamine small InChI 1 C19H25NO c1 2 3 6 15 18 20 19 21,16 11 7 4 8 12 16 17 13 9 5 10 14 17 h4 5,7 14,18,21H,2 3,6,15,20H2,1H3 InChIKey ZVRZJTRBWTVKOJ UHFFFAOYAU StdInChI 1S C19H25NO c1 2 3 6 15 18 20 19 21,16 11 7 4 8 12 16 17 13 9 5 10 14 17 h4 5,7 14,18,21H,2 3,6,15,20H2,1H3 StdInChIKey ZVRZJTRBWTVKOJ UHFFFAOYSA N bioavailability protein bound metabolism elimination half life excretion pregnancy category legal status routes of administration Hexapradol International Nonproprietary Name INN , also referable to as butyl hydroxy phenylamphetamine , is a psychostimulant drug of the substituted amphetamine amphetamine class which was never marketed. ref name Ganellin1997 cite book title Dictionary of Pharmacological Agents Volume 2 url http books.google.com books?id A0THacd46ZsC&pg PA1023 accessdate 26 April 2012 publisher CRC Press isbn 978 0 412 46630 4 page 1023 ref See also Phenylmethamphetamine 3,3 Diphenylcyclobutanamine Phenylpropanolamine Pipradol References Reflist Stimulants Phenethylamines Category Alcohols Category Amines Category Phenethylamines Category Stimulants ... more details
about the stimulant drug the glycoprotein Gp130 Drugbox verifiedrevid 451605938 IUPAC name 2 phenyl 5,5 dimethylmorpholine image G 130 structure.png Clinical data tradename pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU Unscheduled S2 S3 S4 S5 S6 S7 S8 S9 legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL P POM CD Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CAS number Ref cascite correct ?? CAS number 42013 48 9 ATC prefix ATC suffix PubChem 97711 DrugBank Ref drugbankcite correct drugbank DrugBank Chemical data C 12 H 17 N 1 O 1 molecular weight 191.269 g mol smiles c1ccccc1C CN2 OCC2 C C G 130 GP 130 , 2 Phenyl 5,5 dimethyltetrahydro 1,4 oxazine ref Cite patent GB 1336732 Diethanolamine Derivatives. ref is a drug with stimulant and anorectic effects, related to phenmetrazine . ref name pmid4740767 cite journal author Fanelli O title Pharmacological and toxicological study of a new psychotropic stimulant the 2 phenyl 5 dimethyl tetrahydro 1,4 oxazine, in comparison with d,l amphetamine, phenmetrazine and pemoline Mg journal Arzneimittel Forschung volume 23 issue 6 pages 810 6 year 1973 month June pmid 4740767 doi url ref ref name pmid4479774 cite journal author Fanelli O, Mazzoncini V, Ferri S title Toxicological and teratological study of 2 phenyl 5,5 dimethyl tetrahydro 1,4 oxazine hydrochloride G 130 , a psychostimulant drug journal Arzneimittel Forschung volume 24 issue 10 pages 1627 32 year 1974 month October pmid 4479774 doi url ref ref name pmid4480283 cite journal author Fanelli O, Mazzoncini V, Trallori L title Antagonism of psychostimulant 2 phenyl 5,5 dimethyl tetrahydro 1,4 oxazine hydrochloride G 130 to central nervous system depressing drugs. Monoamine oxidase inhibitory activity and norepinephrine and serotonin induced changes. Comparison with dL amphetamine journal Arz ... more details
unsuccessfully treated with traditional psychostimulant amphetamine therapy due to lack of effectiveness or intolerance of the psychostimulant. Nadolol was then added to the psychostimulant therapy ... side effects. This suggested the combination of nadolol and the psychostimulant might be effective ... more details
Drugbox Verifiedfields changed verifiedrevid 462091934 IUPAC name 1 phenyl 3,3 bis pyridin 4 ylmethyl 1,3 dihydro 2 H indol 2 one image Linopirdine.png Clinical data tradename pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU Unscheduled S2 S3 S4 S5 S6 S7 S8 S9 legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL P POM CD Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CAS number Ref cascite changed ?? CAS number 105431 72 9 ATC prefix N06 ATC suffix BX09 PubChem 3932 IUPHAR ligand 2599 DrugBank Ref drugbankcite correct drugbank DrugBank ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 3795 UNII Ref fdacite correct FDA UNII I5TB3NZ94T KEGG Ref keggcite correct kegg KEGG D04741 ChEMBL Ref ebicite correct EBI ChEMBL 319111 Chemical data C 26 H 21 N 3 O 1 molecular weight 391.465 g mol smiles O C2N c1ccccc1C2 Cc3ccncc3 Cc4ccncc4 c5ccccc5 InChI 1 C26H21N3O c30 25 26 18 20 10 14 27 15 11 20,19 21 12 16 28 17 13 21 23 8 4 5 9 24 23 29 25 22 6 2 1 3 7 22 h1 17H,18 19H2 InChIKey YEJCDKJIEMIWRQ UHFFFAOYAH StdInChI Ref stdinchicite correct chemspider StdInChI 1S C26H21N3O c30 25 26 18 20 10 14 27 15 11 20,19 21 12 16 28 17 13 21 23 8 4 5 9 24 23 29 25 22 6 2 1 3 7 22 h1 17H,18 19H2 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey YEJCDKJIEMIWRQ UHFFFAOYSA N Linopirdine is a psychostimulant nootropic , which has neuroprotective effects. It acts as a potassium channel blocker, and releases acetylcholine , which is probably responsible for its nootropic action. See also Besipirdine Sibopirdine References Reflist Unreferenced date April 2010 Potassium channel blockers Psychostimulants, agents used for ADHD and nootropics Category Pyridines Category Nootropics Category Indolines Category Lactams Category Potassium channel blockers nervous system drug stub ... more details
Drugbox verifiedrevid 450988207 IUPAC name R phenyl 2 R piperidin 2 yl methyl acetate image Phacetoperane chemical structure.png Clinical data tradename pregnancy category legal status Rx only routes of administration Oral Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number 24558 01 8 ATC prefix none ATC suffix PubChem 65715 Chemical data C 14 H 19 N 1 O 2 molecular weight 233.31 g mol Levophacetoperane Lidepran is a psychostimulant developed by Rhone Poulenc in the 1950s. ref US Patent 2928835 New Esters ref The drug has been used as an antidepressant and anorectic . ref Delbeke FT, Debackere M. Isolation and detection of methylphenidate, phacetoperane and some other sympatomimetic central nervous stimulants with special reference to doping. I. Gas chromatographic detection procedure with electron capture detection for some secondary amines. Journal of Chromatography . 1975 Mar 26 106 2 412 7. ref ref name isbn0 911910 13 1 cite book author O Neil, Maryadele J. title The Merck index an encyclopedia of chemicals, drugs, and biologicals publisher Merck Research Laboratories location Rahway, NJ year 2001 pages isbn 0 911910 13 1 oclc doi url ref It is the reverse ester of methylphenidate . The reverse esters of many drugs which contain an ester group in their structure such as pethidine and cocaine show similar activity to the parent compound. ref Janssen PAJ, Eddy NB. Compounds Related to Pethidine IV. New General Chemical Methods of Increasing the Analgesic Activity of Pethidine. Journal of Medicinal and Pharmaceutical Chemistry . 1960 2 1 31 45. ref See also Methylphenidate References Reflist 2 Stimulants Antidepressants Anorectics Adrenergics Dopaminergics Category Antidepressants Category Anorectics Category Stimulants Category Piperidines Category Acetate esters gastrointestinal drug stub nervous system drug stub ... more details
Drugbox IUPAC name 2 3 methyl 2 phenylmorpholin 4 yl ethyl 2 phenylbutanoate image Fenbutrazate.png Clinical data tradename pregnancy category legal status Rx only routes of administration Oral Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number 4378 36 3 ATC prefix none ATC suffix PubChem 20395 ChemSpiderID 19210 UNII Ref fdacite correct FDA UNII BKY8H56395 Chemical data C 23 H 29 N 1 O 3 molecular weight 367.48 g mol smiles O C OCCN1C C OCC1 c2ccccc2 C C c3ccccc3 CC Fenbutrazate International Nonproprietary Name INN , also known as phenbutrazate British Approved Name BAN , is a psychostimulant used as an appetite suppressant under the trade names Cafilon , Filon , and Sabacid in Europe , Japan , and Hong Kong . ref name isbn0 412 46630 9 cite book author David J. Triggle title Dictionary of Pharmacological Agents publisher Chapman & Hall CRC location Boca Raton year 1996 pages isbn 0 412 46630 9 oclc doi url http books.google.com books?id DeX7jgInYFMC&lpg PA875&as brr 3&pg PA875 v onepage&f false ref ref name pmid2874968 cite journal author Keup W title Use, indications and distribution in different countries of the stimulant and hallucinogenic amphetamine derivatives under consideration by WHO journal Drug and Alcohol Dependence volume 17 issue 2 3 pages 169 92 year 1986 month June pmid 2874968 doi 10.1016 0376 8716 86 90007 4 url http linkinghub.elsevier.com retrieve pii 0376 8716 86 90007 4 ref It is a chemical derivative derivative of phenmetrazine and may function as a prodrug to it similarly to phendimetrazine . ref name urlwhqlibdoc.who.int cite web url http whqlibdoc.who.int trs WHO TRS 729.pdf title WHO Expert Committee on Drug Dependence 22nd Report format PDF accessdate 2010 03 24 ref It is not known to be a controlled substance anywhere in the world as of yet. See also Morazone Phendimetrazine Phenmetrazine References Reflist Stimulants Anorectics Adrenergics Dopaminergics Phenethylamines Category Anor ... more details
Drugbox verifiedrevid 445386260 IUPAC name 3,3 diphenylcyclobutan 1 amine image 3,3 Diphenylcyclobutanamine.png Clinical data tradename pregnancy category legal status Uncontrolled routes of administration Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number ATC prefix none ATC suffix PubChem 47486 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 43204 Chemical data C 16 H 17 N 1 molecular weight 223.31 g mol smiles c1ccc cc1 C3 c2ccccc2 CC N C3 InChI 1 C16H17N c17 15 11 16 12 15,13 7 3 1 4 8 13 14 9 5 2 6 10 14 h1 10,15H,11 12,17H2 InChIKey IABBZBVTZRKDFW UHFFFAOYAL StdInChI Ref stdinchicite correct chemspider StdInChI 1S C16H17N c17 15 11 16 12 15,13 7 3 1 4 8 13 14 9 5 2 6 10 14 h1 10,15H,11 12,17H2 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey IABBZBVTZRKDFW UHFFFAOYSA N 3,3, Diphenylcyclobutanamine is a psychostimulant drug which was originally prepared as an antidepressant in the late 1970s. ref name pmid22757 cite journal author Carnmalm B, R msby S, Renyi AL, Ross SB, Ogren SO title Antidepressant agents. 9. 3,3 Diphenylcyclobutylamines, a new class of central stimulants journal Journal of Medicinal Chemistry volume 21 issue 1 pages 78 82 year 1978 month January pmid 22757 doi 10.1021 jm00199a014 url ref It appears to reuptake inhibitor inhibit the reuptake of serotonin , norepinephrine , and dopamine , and may also induce their releasing agent release as well. ref name pmid22757 The N methyl and N , N dimethyl structural analog analogue s of the compound are also known and are more potency pharmacology potent . ref name pmid22757 All three agents produce locomotor stimulation in animal studies, with the tertiary amine being the strongest. ref name pmid22757 See also beta Phenylmethamphetamine Phenylmethamphetamine Fezolamine References Reflist Stimulants Antidepressants Adrenergics Dopaminergics Serotonergics DEFAULTSORT Diphenylcyclobutanamine, 3,3 Category Amines Category Ant ... more details
Drugbox IUPAC name 1 4 chlorophenyl 1 hydroxy 1,4 dihydro 1,2,4 triazino 6,1 a isoquinolin 5 ium image Trazium.png Clinical data tradename pregnancy category legal status Uncontrolled routes of administration Mouth Oral Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number 97110 59 3 ATC prefix none ATC suffix PubChem 72166 ChemSpiderID 65139 Chemical data C 17 H 13 Cl 1 N 3 O 1 molecular weight 310.76 g mol Trazium EGYT 3,615 is an antidepressant drug which was never marketed. ref name isbn0 412 46630 9 cite book author David J. Triggle title Dictionary of Pharmacological Agents publisher Chapman & Hall CRC location Boca Raton year 1996 pages isbn 0 412 46630 9 oclc doi url http books.google.com books?id A0THacd46ZsC&lpg PA2013&ots IIkjlIrc8 &dq trazium&pg PA2013 v onepage&q&f false ref It has psychostimulant like effects and its actions appear to be mediated by the dopaminergic and adrenergic systems. ref name pmid2551306 cite journal author Gyerty n I, Pet cz L, Bajn gel J, et al. title Possible involvement of the dopaminergic system in the mode of action of the potential antidepressant trazium esilate journal Arzneimittel Forschung volume 39 issue 7 pages 775 81 year 1989 month July pmid 2551306 doi url ref References Reflist Stimulants Antidepressants Adrenergics Dopaminergics Category Antidepressants Category Stimulants Category Triazines Category Organochlorides Category Quaternary ammonium compounds ... more details
Drugbox IUPAC name 4 4 chlorophenyl 6 methyl 3 phenyltetrahydro 2 H pyran 2 one image Lomevactone.png Clinical data tradename pregnancy category legal status routes of administration Pharmacokinetic data bioavailability metabolism elimination half life excretion Identifiers CAS number 81478 25 3 ATC prefix None ATC suffix PubChem 100079 ChemSpiderID 90435 UNII Ref fdacite correct FDA UNII TP71SPS85C Chemical data C 18 H 17 Cl 1 O 2 molecular weight 300.78 g mol smiles Clc1ccc cc1 C2C C O OC C C2 c3ccccc3 Lomevactone DR 250 is a psychostimulant and antidepressant drug which was chemical synthesis synthesized and studied in the 1980s, but was never marketed. ref name isbn0 412 46630 9 cite book author David J. Triggle title Dictionary of pharmacological agents publisher Chapman & Hall location London year 1997 pages isbn 0 412 46630 9 oclc doi url http books.google.com books?id A0THacd46ZsC&lpg PA1231&dq lomevactone&pg PA1231 v onepage&q lomevactone&f false ref ref name pmid6136063 cite journal author Poncelet M, Chermat R, Soubrie P, Simon P title The progressive ratio schedule as a model for studying the psychomotor stimulant activity of drugs in the rat journal Psychopharmacology volume 80 issue 2 pages 184 9 year 1983 pmid 6136063 doi 10.1007 BF00427967 url ref References Reflist Antidepressants Stimulants Category Antidepressants Category Ketones Category Organochlorides Category Pyrans Category Stimulants ... more details
in LMA, and is not psychostimulant. The effects are not long lasting. More recently see attachment ... in circulating triglycerides. The reason for weightloss is not going to be thermogenic or psychostimulant ... more details
Drugbox IUPAC name R 1 Phenyl N propylpentan 2 amine image Phenylpropylaminopentane.svg width 200px Clinical data tradename routes of administration Identifiers CAS number 784118 64 5 PubChem 10262369 ChemSpiderID 21106218 Chemical data C 14 H 23 N 1 molecular weight 205.35 1 Phenyl 2 propylaminopentane PPAP is a drug with an unusual effects profile. It can loosely be grouped with the stimulant or antidepressant drug families, but its mechanism of action is quite different. ref Knoll J, Knoll B, Torok Z, Timar J, Yasar S. The pharmacology of 1 phenyl 2 propylamino pentane PPAP , a deprenyl derived new spectrum psychostimulant. Archives Internationales de Pharmacodynamie et de Therapie . 1992 Mar Apr 316 5 29. ref PPAP is classified as a Catecholamine catecholaminergic and serotonergic activity enhancer. This means that it stimulates the Action potential impulse propagation mediated transmitter release of the neurotransmitter s dopamine , norepinephrine and serotonin in the brain although unlike the newer and more potent compound 1 Benzofuran 2 yl 2 propylaminopentane BPAP , it has less impact on serotonin release and affects mainly the catecholamines . Unlike stimulant drugs like amphetamines , which release a flood of monoamine neurotransmitters in an uncontrolled manner, PPAP instead only increases the amount of neurotransmitter that gets released when a neuron is stimulated by receiving an impulse from a neighbouring neuron. So while both amphetamines and PPAP increase the amount of neurotransmitters that get released, amphetamines cause neurons to dump neurotransmitter stores into the synapse regardless of external input, while with PPAP the pattern of neurotransmitter release is not changed, but when the neuron would normally release neurotransmitter, a larger amount than normal is released. ref Knoll J, Miklya I, Knoll B, Marko R, Kelemen K. Deprenyl and 1 phenyl 2 propylaminopentane, PPAP , act primarily as potent stimulants of action potential transmitter re ... more details
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