chembox Verifiedfields changed verifiedrevid 400995112 Name Punicalagin ImageFile Punicalagin1.png ImageSize 228px ImageName Chemical structure of punicalagin IUPACName OtherNames 2,3 S hexahydroxydiphenoyl 4,6 S,S gallagyl D glucose br punicalagin br punicalagin Section1 Chembox Identifiers CASNo Ref cascite correct ?? CASNo 65995 63 3 PubChem 16129869 ChEMBL Ref ebicite changed EBI ChEMBL 506814 SMILES C1C C OC O C2 CC C C C2C3 C C C4C5 C3C O OC6 C C C C7 C C C C C7C O O1 O O O C C56 C O O4 O O O O O O O C8C OC O C9 CC C C C9C1 C C C C C1C O O8 O O O O O O C O O Section2 Chembox Properties Formula C sub 48 sub H sub 28 sub O sub 30 sub MolarMass 1084.71 g mol ExactMass 1084.06654 u Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Punicalagin is an ellagitannin , a type of phenolic compounds. It is found in forms alpha and beta in pomegranate s Punica granatum , in Terminalia catappa and Terminalia myriocarpa ref Cite doi 10.1055 s 2002 32549 ref , and in Combretum molle , the velvet bushwillow, is a plant species found in South Africa. ref name Asres2 Cite doi 10.1002 ptr.897 ref . These three genera are all Myrtales and the last two are both Combretaceae . Health effects Punicalagins are the largest molecule found intact in rat plasma after oral ingestion ref Cerda et al. Eur J Nutr. 2003 Jan 42 1 , pp. 18 28 ref and were found to show no toxic effects in rats who were given a 6 diet of punicalagins for 37 days. ref Cerda et al. J. Agric. Food Chem. 2003, 51, pp. 3493 3501 ref Punicalagins are also found to be the major component responsible for pomegranate juice s antioxidant and health benefits. ref Gil et al. J Agric Food Chem 2000 48 10 , pp. 4581 4589 ref Punicalagin is water soluble and has high bioavailability. They are known to hydrolyze into smaller phenolic compounds such as ellagic acid in vivo where one potential mechanism is hydrolysis across the Mitochondrion mitochondrial membrane of cu ... more details
extracts of whole pomegranate and or are standardized to punicalagins, the marker compound ... extracts, especially pomegranate concentrate normalized to punicalagins. ref Seeram et al. J Nutr Biochemistry 2005 16 , pp. 360 367 ref A pomegranate extract standardized to punicalagins marketed under ... afford the ellagitannin punicalagins. The substance was found to be active against methicillin resistant ... Ferreira, J. Agric. Food Chem., 2009, 57 18 , pages 8344 8349, doi 10.1021 jf901931b ref Punicalagins ... in rats who were given a 6 diet of punicalagins for 37 days. ref cite journal author Cerd B, Cer n ... 11 pages 3493 501 year 2003 month May pmid 12744688 doi 10.1021 jf020842c ref Punicalagins are also ... more details
ellagitannin s, also called punicalagins , are tannins with free radical scavenging properties ... 18468784 doi 10.1016 j.canlet.2008.03.043 ref Punicalagins are absorbed into the human body and may ... and punicalagins are converted to urolithins which have unknown biological activity in vivo ... 717 25 date 19 July 2009 pmid 19616930 doi 10.1016 j.jnutbio.2009.04.012 ref The different punicalagins ... molecule Pomegranate ellagitannin punicalagins are metabolized. However, ingested ellagic acid ... more details
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