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Encyclopedia results for Pyran

Pyran





Encyclopedia results for Pyran

  1. Pyran

    molecules, such as the pyranoflavonoid s. The term pyran is also often applied to the saturated ... Piran it Pirano chimica nl Pyraan ja pl Piran zwi zek chemiczny pt Pirano sv Pyran zh ...   more details



  1. C5H6O

    DISPLAYTITLE C sub 5 sub H sub 6 sub O The molecular formula C sub 5 sub H sub 6 sub O may refer to 2 Methylfuran Pyran MolFormDisambig fr C5H6O ...   more details



  1. 4H (disambiguation)

    4 H is a youth organization administered by the USDA. 4H may also refer to Curtiss JN 4 H, an American biplane 4H, a List of Metrobus routes Washington, D.C. Washington, D.C. Metrobus route 4H pyran 4H SiC, one of the polymorphs of silicon carbide Isotopes of hydrogen Hydrogen 4 sup 4 sup H quadrium , An Isotope of Hydrogen. See also H4 disambiguation Letter NumberCombDisambig it 4H ...   more details



  1. 2H

    2H or 2 H may refer to 2H lead, a type of lead in a pencil 2H, a type of Toyota H engine Douglas O 2H, a model of Douglas O 2 Chaparral 2H, one model of Chaparral Cars Aptera 2h, a model in the Aptera 2 Series SSH 2H WA , alternate designation for Washington State Route 290 2H, a disgnation for chemicals with two hydrogen molecules 2H pyran, a form of Pyran 2H 1 benzopyran, a form of Benzopyran 2H pyran 2 one, a form of 2 Pyrone See also H2 disambiguation Letter NumberCombDisambig de 2H it 2H ...   more details



  1. Dihydropyran

    hydrogen is placed just in front of the parent hydride pyran . ref A Guide to IUPAC Nomenclature of Organic ... pyran tetrahydropyran References reflist DEFAULTSORT Dihydropyran, 2,3 Category Dihydropyrans de ...   more details



  1. Rose oxide

    chembox verifiedrevid 392964336 ImageFile Rosenoxide.svg ImageSize IUPACName Tetrahydro 4 methyl 2 2 methylpropenyl 2 H pyran OtherNames Section1 Chembox Identifiers CASNo 16409 43 1 CASOther br 876 17 5 &minus cis br 876 18 6 &minus trans Section2 Chembox Properties Formula C sub 10 sub H sub 18 sub O sub sub MolarMass 154.25 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Rose oxide is an organic compound of the pyran class and the monoterpene class and a fragrance found in Rose roses and rose oil . The compound has both a Cis trans isomerism cis and a trans isomer , each with a and &minus stereoisomer, but only the &minus cis isomer odor treshhold 0.5 ppb is responsible for the typical rose floral green fragrance. ref Dieter Martinetz und Roland Hartwig Taschenlehrbuch der Riechstoffe ein Lexikon von A Z. Verlag Harri Deutsch 1998 ISBN 3 8171 1539 3 S. 330ff. ref Rose oxide also contributes to the flavor of some fruits such as lychee and Gew rztraminer . File Rosenoxides.svg 200px Rose oxide isomers Rose oxide is produced industrially beginning with photooxygenation of citronellol to give the allyl hydroperoxide which is then reduced with sodium sulfite to provide the diol . Ring closure with sulfuric acid forms both the cis and trans isomers in equal amounts. ref cite DOI 10.1021 op900076g ref File Synthesis rosenoxide.svg 500px Rose oxide synthesis References Reflist Category alkenes Category Tetrahydropyrans Category Monoterpenes de Rosenoxid fa it Ossido di rosa ja ru ...   more details



  1. Pyranoflavonoid

    The pyranoflavonoids are a type of flavonoids possessing a pyran group. Cyclocommunin is another natural pyranoflavonoid. ref http www.sciencedirect.com science? ob ArticleURL& udi B6T38 3W37BRF B& user 10& coverDate 03 2F31 2F1999& rdoc 1& fmt high& orig search& sort d& docanchor &view c& acct C000050221& version 1& urlVersion 0& userid 10&md5 4d32e8c2e208ba5e24ec858bdd5b2df5 Stimulation of respiratory burst by cyclocommunin in rat neutrophils is associated with the increase in cellular Ca2 and protein kinase C activity. Jih Pyang Wang, Lo Ti Tsao, Shue Ling Raung, Pei Ling Lin and Chun Nan Lin, Free Radical Biology and Medicine, Volume 26, Issues 5 6, March 1999, Pages 580 588 ref Pyranoanthocyanins main Pyranoanthocyanin Pyranoisoflavones Alpinumisoflavone Di O methylalpinumisoflavone 4 methyl alpinumisoflavone Pyranoflavonols Karanjachromene References reflist flavonoids Category Flavonoids Natural phenol stub ...   more details



  1. O-2113

    Drugbox Verifiedfields changed verifiedrevid IUPAC name 6aR,10aR 3 1 ethanesulfonylamino 5 methyl hexan 5 yl 6a,7,10,10a tetrahydro 6,6,9 trimethyl 6H dibenzo b,d pyran image O 2113 structure.png width 260 Clinical data pregnancy category legal status Identifiers CAS number Ref cascite changed ?? CAS number ATC prefix ATC suffix PubChem 11775273 ChemSpiderID 26333261 InChI 1 C25H39NO4S c1 7 31 28,29 26 13 9 8 12 24 3,4 18 15 21 27 23 19 14 17 2 10 11 20 19 25 5,6 30 22 23 16 18 h10,15 16,19 20,26 27H,7 9,11 14H2,1 6H3 t19 ,20 m1 s1 InChIKey UMJJTCXPFDHKGJ WOJBJXKFBM StdInChI 1S C25H39NO4S c1 7 31 28,29 26 13 9 8 12 24 3,4 18 15 21 27 23 19 14 17 2 10 11 20 19 25 5,6 30 22 23 16 18 h10,15 16,19 20,26 27H,7 9,11 14H2,1 6H3 t19 ,20 m1 s1 StdInChIKey UMJJTCXPFDHKGJ WOJBJXKFSA N DrugBank Ref drugbankcite correct drugbank DrugBank Chemical data C 25 H 39 N 1 O 4 S 1 molecular weight 449.645 g mol smiles C13CC C C CC3c2c OC1 C C cc C C C CCCCNS O O CC cc2O O 2113 is a drug that is a classical cannabinoid derivative, which acts as a potent agonist for cannabinoid receptor s, producing sedation , hypothermia and analgesia in animal studies. ref Martin et al. SULFONAMIDE CANNABINOID AGONISTS AND ANTAGONISTS. US Patent 7279500, Oct 9 2007 ref See also O 2050 O 2372 O 2545 References reflist Cannabinoids Category Cannabinoids cannabinoid stub ...   more details



  1. Benzopyran

    Chembox Watchedfields changed verifiedrevid 464365209 ImageFile 4H Chromen.svg Section1 Chembox Identifiers ChemSpiderID 10651828 ChemSpiderID Ref chemspidercite correct chemspider SMILES StdInChI 1S C9H7O c1 2 6 9 8 4 1 5 3 7 10 9 h1 7H StdInChI Ref stdinchicite correct chemspider StdInChIKey QZHPTGXQGDFGEN UHFFFAOYSA N StdInChIKey Ref stdinchicite correct chemspider Section2 Chembox Properties C 9 H 8 O 1 ExactMass 132,16 g mol sup 1 sup Benzopyran is an Polycyclic compound polycyclic organic compound that results from the fusion of a benzene ring to a heterocyclic pyran ring. According to IUPAC nomenclature it is called chromene . There are two isomers of benzopyran that vary by the orientation of the fusion of the two rings compared to the oxygen, resulting in 1 benzopyran chromene and 2 benzopyran isochromene the number denotes where the oxygen atom is located by standard naphthalene like nomenclature. The radical chemistry radical form of benzopyran is paramagnetic . The unpaired electron is delocalized over the whole benzopyran molecule, rendering it less reactive than one would expect otherwise, a similar example is the cyclopentadienyl radical. Commonly, benzopyran is encountered in the reduced state, where it is partially saturated with one hydrogen, introducing a tetrahedral CH sub 2 sub group in the pyran ring. There are thus many different structural isomers due to multiple possible positions of the oxygen atom and the tetrahedral carbon class wikitable Structural isomers of chromene center File 2H Chromen.svg 120px br 2 H chromene br 2 H 1 benzopyran center center File 4H Chromen.svg 120px br 4 H chromene br 4 H 1 benzopyran center center 5 H chromene center center 7 H chromene center center 8a H chromene center class wikitable Structural isomers of isochromene center File 1H Isochromen.svg 120px br 1 H isochromene br 1 H 2 benzopyran center center File 3H Isochromen.svg 120px br 3 H isochromene br 3 H 2 benzopyran center are 4a H or 6 H or 8 H isochro ...   more details



  1. Annulation

    distinguish Annulment Annulation derived from annulus mathematics annular , occasionally annelation in organic chemistry is a chemical reaction in which a new ring is constructed on another molecule often another ring . ref GoldBookRef title annulation url http goldbook.iupac.org A00367.html GoldBookRef title annelation url http goldbook.iupac.org A00365.html ref Image AnnulationStrategies.png 400px Annulation A intramolecular ring closing B transannulation C cycloaddition Examples are the Robinson annulation , Danheiser annulation and certain cycloaddition s. Annular molecules are constructed from side on condensed cyclic segments, for example helicene s and acene s. In transannulation a bicyclic molecule is created by intramolecular carbon carbon bond formation in a large monocyclic ring. An example is the samarium II iodide induced ketone alkene cyclization of 5 methylenecyclooctanone which proceeds through a ketyl intermediate ref Construction of Bicyclic Ring Systems via a Transannular SmI2 Mediated Ketone Olefin Cyclization Strategy Gary A. Molander, Barbara Czak , and Michael Rheam J. Org. Chem. 2007 72 5 pp 1755 1764 Article DOI 10.1021 jo062292d ref Image KetoneOlefinCyclization.png 400px Ketone olefin cyclization Benzannulation The term benzannulated compounds refers to derivatives of cyclic compound s usually aromatic which are fused to a benzene ring. Examples are listed in the table below class wikitable style text align center Benzannulated derivative Source of cyclic compound Benzopyrene Pyrene Quinoline rowspan 2 Pyridine Isoquinoline Chromene rowspan 2 Pyran Isochromene Indole rowspan 2 Pyrrole Isoindole Benzofuran rowspan 2 Furan Isobenzofuran Benzimidazole Imidazole Transannular interaction A transannular interaction in chemistry is any chemical interaction favorable or nonfavorable between different chemical bond non bonding molecule molecular functional group groups in a large ring or macrocycle ref Experimental evidence in support of transannul ...   more details



  1. Meconic acid

    chembox verifiedrevid 437107655 ImageFile Meconic acid.svg ImageSize 150 IUPACName 3 Hydroxy 4 oxo 4 H pyran 2,6 dicarboxylic acid OtherNames Section1 Chembox Identifiers CASNo 497 59 6 PubChem 5351448 SMILES C1 C OC C O O C O C1 O C O O Section2 Chembox Properties Formula C sub 7 sub H sub 4 sub O sub 7 sub MolarMass 200.10 Appearance colorless crystals Density MeltingPt Solubility Meconic acid , also known as acidum meconicum and poppy acid , is a chemical substance found in certain plants of the Papaveraceae family poppy such as Papaver somniferum opium poppy and Papaver bracteatum . Meconic acid constitutes about 5 of opium and can be used as an analytical marker for the presence of opium. Meconic acid has erroneously been described as a mild narcotic , but it has little or no physiological activity, and is not used medicinally. Meconic acid forms salt chemistry salts with alkaloid s and metal s. These salts as well as meconic acid ester s are called meconates . Meconic acid was first isolated by Friedrich Sert rner in 1805. Chemistry Meconic acid is a dicarboxylic acid . Its structure contains two carboxylic acid functional group groups COOH and one keto group O attached to a pyran ring. Meconic acid gives a red color with ferric chloride . Meconic acid is colorless and is only slightly soluble in water but readily soluble in alcohol. See also Opium Muconic acid , an unrelated dicarboxylic acid References cite journal title Poppy Acid Synthesis and Crystal Chemistry author Scott Lovell, Paramjeet Subramony, and Bart Kahr journal J. Am. Chem. Soc. volume 121 issue 30 pages 7020 7025 year 1999 url doi 10.1021 ja990402a Category Dicarboxylic acids Category 4 Pyrones Category Alcohols de Mekons ure fr Acide m conique ja pl Kwas mekonowy ro Acid meconic ...   more details



  1. JWH-133

    6aR,10aR 3 1,1 Dimethylbutyl 6a,7,10,10a tetrahydro 6,6,9 trimethyl 6H dibenzo b,d pyran is selective ...   more details



  1. Xanthene

    Distinguish xanthine Unreferenced date December 2009 Chembox Verifiedfields changed Watchedfields changed verifiedrevid 412200450 ImageFile Xanthen.svg ImageSize 200px IUPACName 9H Xanthene OtherNames Dibenzo a , e pyran br 10 H 9 oxaanthracene Section1 Chembox Identifiers Abbreviations CASNo 92 83 1 CASNo Ref cascite correct CAS EINECS 202 194 4 PubChem ChEMBL Ref ebicite changed EBI ChEMBL 486760 SMILES c1 Oc2ccccc2C3 c3cccc1 PubChem 7107 ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID 6840 InChI 1 C13H10O c1 3 7 12 10 5 1 9 11 6 2 4 8 13 11 14 12 h1 8H,9H2 InChIKey GJCOSYZMQJWQCA UHFFFAOYAO StdInChI Ref stdinchicite changed chemspider StdInChI 1S C13H10O c1 3 7 12 10 5 1 9 11 6 2 4 8 13 11 14 12 h1 8H,9H2 StdInChIKey Ref stdinchicite changed chemspider StdInChIKey GJCOSYZMQJWQCA UHFFFAOYSA N RTECS MeSHName ChEBI Ref ebicite correct EBI ChEBI KEGG Ref keggcite correct kegg KEGG ATCCode prefix ATCCode suffix ATC Supplemental Section2 Chembox Properties Formula Carbon sub 13 sub Hydrogen sub 10 sub Oxygen MolarMass 182.22 g mol Appearance Yellow solid Density MeltingPt 101 102 C Melting notes BoilingPt 310 312 C Boiling notes Solubility SolubleOther Solvent pKa pKb Section7 Chembox Hazards EUClass EUIndex MainHazards NFPA H NFPA F NFPA R NFPA O RPhrases R42 R43 SPhrases S22 S36 S37 S45 RSPhrases FlashPt Autoignition ExploLimits PEL Xanthene 9 H xanthene, 10 H 9 oxaanthracene is a yellow organic compound organic heterocyclic compound . Its chemical formula is Carbon sub 13 sub Hydrogen sub 10 sub Oxygen . It is soluble in diethyl ether . Its melting point is 101 102 C and its boiling point is 310 312 C. Xanthene is used as a fungicide and it is also a useful intermediate in organic synthesis . Derivatives of xanthene are commonly referred to collectively as xanthenes, and among other uses are the basis of a class of dye s which includes fluorescein , eosin s, and rhodamine s. Xanthene dyes tend to be fluorescent , yellow to pink to bluish red, brillia ...   more details



  1. Tetrahydropyran

    See also Tetrahydrofuran THF Pyran References references Category Protecting groups Category Ether ...   more details



  1. Chromone

    chembox Verifiedfields changed Watchedfields changed verifiedrevid 399524554 ImageFile chromone.svg ImageSize 150px IUPACName Chromen 4 one OtherNames 4 Chromone 1,4 Benzopyrone 4 H Chromen 4 one Benzo gamma pyrone 4 H 1 Benzopyran 4 one 1 Benzopyran 4 one 4 H Benzo b pyran 4 one Section1 Chembox Identifiers CASNo Ref cascite correct ?? CASNo 491 38 3 PubChem 10286 ChEMBL Ref ebicite changed EBI ChEMBL 13311 SMILES C1 CC C2C C1 C O C CO2 ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID 9866 InChI 1 C9H6O2 c10 8 5 6 11 9 4 2 1 3 7 8 9 h1 6H InChIKey OTAFHZMPRISVEM UHFFFAOYAY StdInChI Ref stdinchicite changed chemspider StdInChI 1S C9H6O2 c10 8 5 6 11 9 4 2 1 3 7 8 9 h1 6H StdInChIKey Ref stdinchicite changed chemspider StdInChIKey OTAFHZMPRISVEM UHFFFAOYSA N Section2 Chembox Properties C 9 H 6 O 2 Appearance Density MeltingPt BoilingPt Solubility pKa 2.0 of conjugate acid Section3 Chembox Hazards MainHazards FlashPt Autoignition Chromone or 1,4 benzopyrone is a derivative of benzopyrans benzopyran with a substituted ketone keto group on the pyran ring. It is an isomer of coumarin . Derivatives of chromone are collectively known as chromones . Most, though not all, chromones are also phenylpropanoid s. Examples 6,7 dimethoxy 2,3 dihydrochromone has been isolated from Sarcolobus globosus . Eucryphin , a chromone rhamnoside, can be isolated from the bark of Eucryphia cordifolia . ref Eucryphin, a new chromone rhamnoside from the bark of Eucryphia cordifolia. R. Tschesche, S. Delhvi, S. Sepulveda and E. Breitmaier, Phytochemistry, Volume 18, Issue 5, 1979, pages 867 869, doi 10.1016 0031 9422 79 80032 1 ref Roger Altounyan studied chromones and eventually found disodium cromoglicate . ref HOWELL, J.B. & ALTOUNYAN, R.E. 1967 . A double blind trial of disodium cromoglycate in the treatment of allergic bronchial asthma. Lancet, 2, 539 542. http www.ncbi.nlm.nih.gov entrez query.fcgi?holding npg&cmd Retrieve&db PubMed&list uids 4166895&dopt Abstract Abstract r ...   more details



  1. Proscillaridin

    Drugbox Verifiedfields changed verifiedrevid 464375437 IUPAC name 5 3 S ,8 R ,9 S ,10 R ,13 R ,14 S ,17 R 14 hydroxy 10,13 dimethyl 3 2 R ,3 R ,4 R ,5 R ,6 R 3,4,5 trihydroxy 6 methyltetrahydro 2 H pyran 2 yloxy 2,3,6,7,8,9,10,11,12,13,14,15,16,17 tetradecahydro 1 H cyclopenta a phenanthren 17 yl 2 H pyran 2 one br OR br 3 Rhamnosido 14 hydroxybufa 4,20,22 trienolide image Proscillaridin.png Clinical data tradename Drugs.com drugs.com international proscillaridin pregnancy category legal status routes of administration Pharmacokinetic data bioavailability metabolism excretion Identifiers CAS number Ref cascite changed ?? CAS number 466 06 8 ATC prefix C01 ATC suffix AB01 ChEMBL Ref ebicite correct EBI ChEMBL 600325 PubChem 5284613 DrugBank Ref drugbankcite correct drugbank ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 4447658 UNII Ref fdacite correct FDA UNII KC6BL281EN Chemical data C 30 H 42 O 8 molecular weight 530.650 smiles O C 1O C C C C 1 C H 2CC C 6 O C 2 C CC C H 5 C H 6CC C4 C C H O C H 3O C H C H O C H O C H 3O C CC C 45C InChI 1 C30H42O8 c1 16 24 32 25 33 26 34 27 37 16 38 19 8 11 28 2 18 14 19 5 6 22 21 28 9 12 29 3 20 10 13 30 22,29 35 17 4 7 23 31 36 15 17 h4,7,14 16,19 22,24 27,32 35H,5 6,8 13H2,1 3H3 t16 ,19 ,20 ,21 ,22 ,24 ,25 ,26 ,27 ,28 ,29 ,30 m0 s1 InChIKey MYEJFUXQJGHEQK ALRJYLEOBX StdInChI Ref stdinchicite correct chemspider StdInChI 1S C30H42O8 c1 16 24 32 25 33 26 34 27 37 16 38 19 8 11 28 2 18 14 19 5 6 22 21 28 9 12 29 3 20 10 13 30 22,29 35 17 4 7 23 31 36 15 17 h4,7,14 16,19 22,24 27,32 35H,5 6,8 13H2,1 3H3 t16 ,19 ,20 ,21 ,22 ,24 ,25 ,26 ,27 ,28 ,29 ,30 m0 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey MYEJFUXQJGHEQK ALRJYLEOSA N Proscillaridin is a cardiac glycoside , a kind of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia irregular heartbeat . It is of the bufanolide type and can be obtained from plants of the genus Scilla , notably Scilla maritima . ref ...   more details



  1. ATCvet code QP51

    ATC codes lead P 51 Antiprotozoals vet only anchor QP51A QP51A Agents against protozoal diseases anchor QP51AA QP51AA Nitroimidazole derivatives QP51AA01 Metronidazole QP51AA02 Tinidazole QP51AA03 Ornidazole QP51AA04 Azanidazole QP51AA05 Propenidazole QP51AA06 Nimorazole QP51AA07 Dimetridazole QP51AA08 Ronidazole QP51AA09 Carnidazole QP51AA10 Ipronidazole anchor QP51AB QP51AB Antimony compounds QP51AB01 Meglumine antimonate QP51AB02 Sodium stibogluconate anchor QP51AC QP51AC Nitrofuran derivatives QP51AC01 Nifurtimox QP51AC02 Nitrofural anchor QP51AD QP51AD Arsenic compounds QP51AD01 Arsthinol QP51AD02 Difetarsone QP51AD03 Glycobiarsol QP51AD04 Melarsoprol QP51AD05 Acetarsol QP51AD06 Melarsamin QP51AD53 Glycobiarsol, combinations anchor QP51AE QP51AE Carb anilide s QP51AE01 Imidocarb QP51AE02 Suramin sodium QP51AE03 Nicarbazine anchor QP51AF QP51AF Aromatic di amidine s QP51AF01 Diminazen QP51AF02 Pentamidine QP51AF03 Phenamidine anchor QP51AG QP51AG Sulfonamide medicine Sulfonamide s, plain and in combinations QP51AG01 Sulfadimidine QP51AG02 Sulfadimethoxine QP51AG03 Sulfaquinoxaline QP51AG04 Sulfaclozine QP51AG30 Combinations of sulfonamides QP51AG53 Sulfaquinoxaline, combinations anchor QP51AH QP51AH Pyran es and hydropyranes QP51AH01 Salinomycin QP51AH02 Lasalocid QP51AH03 Monensin QP51AH04 Narasin QP51AH54 Narasin, combinations anchor QP51AJ QP51AJ Triazine s QP51AJ01 Toltrazuril QP51AJ02 Clazuril QP51AJ03 Diclazuril QP51AJ04 Ponazuril anchor QP51AX QP51AX Other antiprotozoal agents QP51AX01 Chiniofon QP51AX02 Emetine QP51AX03 Phanquinone QP51AX04 Mepacrine QP51AX05 Nifursol QP51AX06 Homidium QP51AX07 Diminazen QP51AX08 Halofuginone QP51AX09 Amprolium QP51AX10 Maduramicin QP51AX11 Arprinocid QP51AX12 Dinitolmide QP51AX13 Robenidine QP51AX14 Decoquinate QP51AX16 Aminonitrothiazol QP51AX17 Ethopabate QP51AX18 Diaveridine QP51AX19 Isometamidium QP51AX20 Quinapyramine QP51AX21 Parvaquone QP51AX22 Buparvaquone QP51AX23 Fumagillin QP51AX24 Domperidone QP51AX30 Combin ...   more details



  1. O-2050

    Drugbox Verifiedfields changed verifiedrevid IUPAC name 6aR,10aR 3 1 methanesulfonylamino 4 hexyn 6 yl 6a,7,10,10a tetrahydro 6,6,9 trimethyl 6H dibenzo b,d pyran image O 2050 structure.png width 260 Clinical data pregnancy category legal status Identifiers CAS number Ref cascite changed ?? CAS number ATC prefix ATC suffix PubChem 16102146 ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID DrugBank Ref drugbankcite correct drugbank DrugBank Chemical data C 23 H 31 N 1 O 4 S 1 molecular weight 417.560 g mol smiles O S C O NCCCC CCc cc2O cc OC1 C C c2C3C1CC C C C3 O 2050 is a drug that is a classical cannabinoid derivative, which acts as a silent antagonist for the Cannabinoid receptor 1 CB sub 1 sub Receptor biochemistry receptor . This gives it an advantage in research over many commonly used cannabinoid antagonist s such as rimonabant , which at higher doses act as inverse agonist s at CB sub 1 sub as well as showing off target effects. However while O 2050 acts as a silent antagonist in vitro , some tests in vivo have suggested it may show agonist activity under certain circumstances. ref http cannabinoidsociety.org HTML ICRS.2002.symposium.pdf Martin B, et al. Agonists and silent antagonists in a series of cannabinoid sulfonamides. 12th Annual Symposium on the Cannabinoids, 2002 ref ref Martin et al. SULFONAMIDE CANNABINOID AGONISTS AND ANTAGONISTS. US Patent 7279500, Oct 9 2007 ref ref Gardner A, Mallet PE. Suppression of feeding, drinking, and locomotion by a putative cannabinoid receptor silent antagonist . European Journal of Pharmacology . 2006 Jan 13 530 1 2 103 6. PMID 16380113 ref ref Higuchi S, Irie K, Mishima S, Araki M, Ohji M, Shirakawa A, Akitake Y, Matsuyama K, Mishima K, Mishima K, Iwasaki K, Fujiwara M. The cannabinoid 1 receptor silent antagonist O 2050 attenuates preference for high fat diet and activated astrocytes in mice. Journal of Pharmacological Sciences . 2010 112 3 369 72. PMID 20168044 ref ref Higuchi S, Ohji M, Araki M, Fu ...   more details



  1. Abamectin

    Drugbox Verifiedfields changed Watchedfields changed verifiedrevid 477236952 IUPAC name mixture of br 10E,14E,16E 1R,4S,5 S,6S,6 R,8R,12S,13S,20R,21R,24S 6 S sec butyl 21,24 dihydroxy 5 ,11,13,22 tetramethyl 2 oxo 3,7,19 trioxatetracyclo 15.6.1.14,8.020,24 pentacosa 10,14,16,22 tetraene 6 spiro 2 5 ,6 dihydro 2 H pyran 12 yl 2,6 dideoxy 4 O 2,6 dideoxy 3 O methyl L arabino hexopyranosyl 3 O methyl L arabino hexopyranoside br and br 10E,14E,16E 1R,4S,5 S,6S,6 R,8R,12S,13S,20R,21R,24S 21,22 dihydroxy 6 isopropyl 5 ,11,13,22 tetramethyl 2 oxo 3,7,19 trioxatetracyclo 15.6.1.14,8.020,24 pentacosa 10,14,16,22 tetraene 6 spiro 2 5 ,6 dihydro 2 H pyran 12 yl 2,6 dideoxy 4 O 2,6 dideoxy 3 O methyl L arabino hexopyranosyl 3 O methyl L arabino hexopyranoside image Avermectins.png width 250 Clinical data tradename pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status International Organization for Standardization ISO 1750 approved routes of administration Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CASNo Ref cascite correct CAS CAS number Ref cascite correct ?? CAS number 71751 41 2 CAS supplemental ATCvet yes ATC prefix P54 ATC suffix AA02 ATC supplemental PubChem DrugBank Ref drugbankcite correct drugbank DrugBank ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 8095964 UNII Ref fdacite correct FDA UNII 5U8924T11H KEGG Ref keggcite correct kegg KEGG D02777 ChEMBL Ref ebicite changed EBI ChEMBL 1630577 Chemical data chemical formula Carbon C sub 48 sub Hydrogen H sub 72 sub Oxygen O sub 14 sub B1a br Carbon C sub 47 sub Hydrogen H sub 70 sub Oxygen O sub 14 sub B1b C H N O molecular weight smiles InChI 1 C48H72O14.C47H70O14 c1 11 25 2 43 28 5 17 18 47 62 43 23 34 20 33 ...   more details



  1. Molybdopterin

    chembox Watchedfields changed verifiedrevid 444327795 ImageFile MoPterin.png ImageSize 300px ImageFile2 ImageSize2 IUPACName OtherNames Section1 Chembox Identifiers CASNo Ref cascite correct ?? CASNo 73508 07 3 PubChem 459 SMILES MeSHName molybdopterin Section2 Chembox Properties Formula chem C 10 H 10 N 5 O 6 PS 2 R groups MolarMass 394.33 g mol R H Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Image MoPtSyn.png thumb 300px right Some biosynthetic steps leading to molybdenum pterin, a molydopterin. Molybdopterins , when reacted with molybdenum or tungsten in the form of molybdate or tungstate, are a class of cofactor biochemistry cofactors found in most molybdenum Mo and all tungsten W enzymes. Synonyms for molydopterin are MPT and pyranopterin dithiolate. The nomenclature for this biomolecule can be confusing Molybdopterin per se contains no molybdenum rather, this is the name of the ligand that will eventually bind the active metal. After molydopterin is eventually complexed with molybdate, the complete ligand is usually called molybdenum cofactor . Molydopterin consists of a pyranopterin, a complex heterocycle featuring a pyran fused to a pterin ring. In addition, the pyran ring features two thiolate s, which serve as ligand s in molybdo and tungstoenzymes. In some cases, the alkyl phosphate group is replaced by an alkyl diphosphate nucleotide . Enzymes that contain the molybdopterin cofactor include xanthine oxidase , DMSO reductase , sulfite oxidase , and nitrate reductase . The only molybdenum containing enzymes that do not feature molydopterins are the nitrogenase s enzymes that fix nitrogen . These contain an iron sulfur center of a very different type, which also usually contains molybdenum. However, if molybdenum is present, it is directly bonded to other metal atoms. ref name gramene http pathway.gramene.org META NEW IMAGE?type COMPOUND&object CPD 4 Structure, synthesis, empirical formula for ...   more details



  1. List of MeSH codes (D14)

    Phosphate polyphloretin phosphate MeshNumber D25.720.830 Pyran Copolymer pyran copolymer MeshNumber ...   more details



  1. Perranzabuloe

    infobox UK place static image name Perranzabuloe Church geograph.org.uk 66070.jpg static image width 240 static image caption small Perranzabuloe parish church small country England latitude 50.326 longitude 5.133 official name Perranzabuloe cornish name Pyran yn Treth population 5382 population ref United Kingdom Census 2001 Civil Parish, 2001 unitary england Cornwall Council Cornwall lieutenancy england Cornwall region South West England constituency westminster Truro & Falmouth UK Parliament constituency Truro & Falmouth post town TRURO postcode district TR4 postcode area TR dial code 01872 os grid reference SW 770 520 File Remains of St Piran s Old Church geograph.org.uk 308744.jpg thumb Remains of St Piran s Old Church File St Piran s Cross geograph.org.uk 63222.jpg thumb St Piran s Cross Perranzabuloe lang kw Pyran yn Treth ref cite web url http www.cornish language.org english PlaceNames.asp?view P title Cornish Place Names accessdate 29 January 2009 ref is a coastal civil parishes in England civil parish and a hamlet in Cornwall , England, United Kingdom. The hamlet containing the parish church is situated just over a mile 2  km south of the principal settlement of the parish, Perranporth the hamlet is also seven miles 11  km south southwest of Newquay . ref Ordnance Survey Landranger map sheet 204 Truro & Falmouth ISBN 9780319231494 ref ref Ordnance Survey Landranger map sheet 200 Newquay & Bodmin ISBN 9780319229385 ref Other settlements in the parish include Perrancoombe , Goonhavern , Mount, Cornwall Mount and Callestick . ref Ordnance Survey Explorer Map 104 Redruth & St Agnes ISBN 9780319237052 ref Perranzabuloe parish is bordered to the west by the Atlantic coast and St Agnes, Cornwall St Agnes parish, to the north by Cubert parish, to the east by St Newlyn East and St Allen parishes and to the south by Kenwyn parish. ref name Mapping http mapping.cornwall.gov.uk website ccmap Cornwall Council online mapping Retrieved June 2010 ref The parish p ...   more details



  1. Aucubin

    a cyclopentan C pyran skeleton ref name doi10.1590 S0103 50532001000200004 . Iridoids can consist of ten ... G, Rao P title Synthesis of cyclopenta c pyran skeleton of iridoid lactones journal Tetrahedron volume ...   more details



  1. Tautomer

    chain and pyran forms of glucose and furan form of fructose . Valence tautomerism Valence ...   more details



  1. Swiss Cottage Central Library

    . Wired glass has been replaced with clear Pyran glass to enhance the sense of cross visibility ...   more details




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