PDC may refer to TOCright Chemistry polycrystalline diamond Polycrystalline Diamond Compact , a process and component developed for and used in earth formation Drill bit well drill bits to increase their strength and longevity Pyruvate decarboxylase , a homotetrameric enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde and carbon dioxide Pyruvate dehydrogenase complex , a complex of three enzymes that transform pyruvate into acetyl CoA Cornforth reagent Pyridinium dichromate , a chromium based oxidant used in organic chemistry Computing Professional Developers Conference , a Microsoft conference for software developers Pocket Dream Console , a small handheld game device created by Tomy and Conny in 2006 Personal decompression computer , a device used by scuba divers to monitor their decompression obligation Personal Digital Cellular , a 2G mobile phone standard developed and used exclusively in Japan Programme Delivery Control , a standard to control video recorders using hidden codes in the teletext service Primary Domain Controller , a server computer in a pre Windows 2000 NT server Domain Peripheral DMA controller , A feature of microcontrollers automating internal feeds for data streams Education California State University, San Bernardino Palm Desert Campus General Science Parktronic Parking Distance Control , is a system used in BMW cars to measure the distance between the car and obstacles Pulsed DC , the form of wave produced from a half wave rectifier or a full wave rectifier Pyroclastic flow Pyroclastic density current , a highly energetic ground current of superheated gases containing a high density of suspended pyroclastic fragments resulting from a volcanic explosion Politics and government Christian Democratic People s Party of Switzerland , a political party in Switzerland Partido Dem crata Cristiano disambiguation , several parties Christian Democratic Party Brazil Partido Democrata Crist o Portland Development Commission , Port ... more details
PCC may stand for Biology and chemistry pyrolytic chromium carbide coating Pyrolytic chromium carbide PCC coating by vacuum deposition Precipitated calcium carbonate Propionyl CoA carboxylase Pyridinium chlorochromate Medicine Pheochromocytoma , a neuroendocrine tumor Organizations and companies Partido Comunista de Canarias, the Communist Party of the Canaries Partido Comunista de Cuba, the Cuban Communist Party Partido Comunista Colombiano, the Colombian Communist Party Pacific Coast Conference , a defunct United States college athletic conference The Pacific Conference of Churches , the regional ecumenical organization in the Pacific region Palestinian cultural club Pakistan Christian Congress Palestinian Conciliation Commission Panama Canal Commission Partit dels i les Comunistes de Catalunya Perth City Council Pacific Coffee Company People s Computer Company Clef Club of Jazz and Performing Arts Plainfield Curling Club Plains Conservation Center Polynesian Cultural Center Power Computing Corporation Porirua Porirua City Council Power Corporation of Canada Pradesh Congress Committee , the provincial committee of the Congress Party in India Precision Castparts Corp. in Portland, Oregon Presbyterian Church in Canada Prerogative Court of Canterbury an important English court for probate The British Press Complaints Commission Printed Circuit Corporation Primeiro Comando da Capital , a Brazilian prison gang terrorist group PCC FoliaConcept , the largest design company in Northern Germany PCC Natural Markets , Puget Consumer s Co op Photo Card Caf , a greeting card company Colleges Pabna Cadet College Palmer College of Chiropractic Pasadena City College Pensacola Christian College Piedmont Community College Pitt Community College Pima Community College Polk State College , formerly Polk Community College Portland Community College Presentation College Chaguanas Punjab College of Commerce Penola Catholic College Governmental groups Parochial church council Patents Co ... more details
Unreferenced date December 2009 Orphan date December 2009 border 0 cellpadding 5 cellspacing 0 style margin 1em float right class wikitable colspan 3 Basic aromatic ring systems align center valign bottom Image Pyridine structure.png 67px br Pyridine Image Quinoline structure.png 119px br Quinoline Image Isoquinoline structure.png 126px br Isoquinoline align center valign bottom Image Acridine structure.png 171px br Acridine align center valign bottom Image Pyrazine structure.png 67px br Pyrazine Image Quinoxaline structure.png 119px br Quinoxaline align center valign bottom Image Imidazole structure.png 63px br Imidazole Image Benzimidazole structure.png 113px br Benzimidazole Image Purine structure.png 113px br Purine align center valign bottom Image Pyrazole structure.png 70px br Pyrazole Image Indazole structure.png 120px br Indazole align center valign bottom Image Pyrimidine structure.png 74px br Pyrimidine Image Quinazoline structure.png 126px br Quinazoline align center valign bottom Image Pyridazine structure.png 74px br Pyridazine Image Cinnoline structure.png 126px br Cinnoline Basic aromatic rings are simple aromatic ring aromatic rings in which the lone pair of electron s of a ring nitrogen atom is not part of the aromatic system and extends in the plane of the ring. This lone pair is responsible for the Base chemistry basicity of these nitrogenous base s, similar to the nitrogen atom in amine s. In these compounds the nitrogen atom is not connected to a hydrogen atom. Basic aromatic compounds get Protonation protonated and form aromatic cation s e.g. pyridinium under acid ic conditions. Typical examples of basic aromatic rings are pyridine or quinoline . Several rings contain basic as well as non basic nitrogen atoms, e.g. imidazole and purine . In non basic aromatic rings the lone pair of electron s of the nitrogen atom is delocalized and contributes to the aromatic pi electron system. In these compounds the nitrogen atom is connected to a hydrogen at ... more details
of nonsmall cell pulmonary carcinoma. PDC in DMF Corey and Schmidt Main pyridinium dichromate Pyridinium dichromate PDC is a bright orange solid with the formulae C sub 5 sub H sub 5 ... involving pyridinium dichromate in approtic media issue 52 ref that reaction of saturated primary ... more details
In organic chemistry , the Baker Nathan effect is observed with reaction rate s for certain chemical reaction s with certain substrates where the order in reactivity cannot be explained solely by an inductive effect of substituents. ref HYPERCONJUGATION INTERMEDIATES AND TRANSITION STATES IN REPLACEMENT AND ELIMINATION Peter B.D. de la Mare Pure & Appl. Chem., Vol 56, No. 12, pp 755 1766, 1984 http www.iupac.org publications pac 1984 pdf 5612x1755.pdf ref This effect was described in 1935 by John W. Baker and W. S. Nathan. ref 118. The mechanism of aromatic side chain reactions with special reference to the polar effects of substituents. Part III. The effect of unipolar substituents on the critical energy and probability factors in the interaction of benzyl bromide with pyridine and picoline in various solvents John W. Baker and W. S. Nathan J. Chem. Soc. , 1935 , 519 527, DOI 10.1039 JR9350000519 ref ref 428. The mechanism of aromatic side chain reactions with special reference to the polar effects of substituents. Part IV. The mechanism of quaternary salt formation John W. Baker, Wilfred S. Nathan, J. Chem. Soc. , 1935 , 1840 1844 DOI 10.1039 JR9350001840 ref ref 429. The mechanism of aromatic side chain reactions with special reference to the polar effects of substituents. Part V. The polar effects of alkyl groups John W. Baker, Wilfred S. Nathan, J. Chem. Soc. , 1935 , 1844 1847 DOI 10.1039 JR9350001844 ref They examined the chemical kinetics for the reaction of pyridine with benzyl bromide and with a range of benzyl bromides with different para isomer para alkyl substituents reaction product a pyridinium salt . Image Baker Nathan effect.svg The Baker Nathan effect The reaction is facilitated by electron releasing substituents the inductive effect and in general the observed order with decreasing reactivity is tert butyl isopropyl ethyl group ethyl methyl . The observed order in this particular reaction however was methyl ethyl isopropyl tert butyl. In 1935 Bake ... more details
orphan date April 2010 Notability Academics date October 2009 Paola Zanetti born 22 March 1981 is a Swiss chemist working at Imperial College London . After completing her initial studies at the University of Fribourg working on Reactivity of Pyridinium Salts towards Pd II and their Influence in Pd OAc sub 2 sub catalysed Suzuki Cross Couplings , ref http www.unifr.ch science diplome07 html fr mast.html ref she moved to Imperial College London to complete a PhD under the supervison of Prof. Vernon C. Gibson . The title of her thesis was Transition Metal Complexes for the Mediated Radical Polymerisation of Vinyl Monomers . The results produced during her PhD studies have indicated a previously unknown, fundamental route to catalyst deactivation, and these results have been communicated to the scientific community at various events. Communications and Awards International br The American Chemical Society National Meeting and Exposition Fall 2009, Washington D.C ref Zanetti, Paola C. Marshall, Edward L. Gibson, Vernon C. White, Andrew J. P. Bis salicylaldimino chromium II complexes in the mediated radical polymerization of vinyl acetate Catalytic behavior and monomer rearrangement. Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, August 16 20, INOR 254 , 2009 . ref ref Zanetti, Paola C. Marshall, Edward L. Gibson, Vernon C. White, Andrew J. P. Unexpected monomer rearrangement in the radical polymerization of vinyl acetate mediated by bis salicylaldimino chromium II complexes. Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, August 16 20, INOR 752 , 2009 . ref National br Imperial College London , Annual Postgraduate Symposium, where she won the Poster 2008 and Presentation awards 2009 ref Paola C. Gibson, Vernon C. White, Andrew J. P. Conjugated backbone in the radical polymerisation of styrene, 2008 ref ref Zanetti, Paola C. Marshall, Edward L. Gibson, Vernon C. White, Andrew J. P. Unexpected monomer rearra ... more details
Orphan date December 2011 Oxidation with chromium VI amine complexes involves the conversion of alcohols to carbonyl compounds or more highly oxidized products through the action of chromium VI oxide amine adducts and salts. Representative members of this family of reagents include Collins reagent , pyridinium chlorochromate PCC , and pyridinium dichromate PDC . ref Luzzio, F. A. Org. React. 1998 , 53 , 1. doi 10.1002 0471264180.or053.01 ref Introduction Sarrett identified the adduct of pyridine and chromium VI oxide Collins reagent as a selective compound for the oxidation of primary and secondary alcohols to carbonyl compounds. ref Poos, G. I. Arth, G. E. Beyler, R. E. Sarrett, L. H. J. Am. Chem. Soc. , 1953 , 75 , 422. ref Despite its selectivity, Collins reagent suffers from difficulties associated with its preparation, stability, and efficiency. The less reactive adducts pyridinium chlorochromate PCC and pyridinium dichromate PDC are more easily handled and more selective than Collins reagent in oxidations of alcohols. These reagents, as well as other, more exotic adducts of nitrogen heterocycles with chromium VI , facilitate a number of oxidative transformations of organic compounds, including cyclization to form tetrahydrofuran derivatives and allylic transposition to afford enones from allyl ic alcohols. Oxidation with chromium VI amines has two primary limitations. Operationally, the tarry byproducts of chromium oxidations cause reduced yields and product sequestration. ref Ratcliffe, R. Rodehorst, R. J. Org. Chem. , 1970 , 35 , 4000. ref In addition, Cr VI amines particularly PCC may react with acid labile functionality. Thus, these agents have been employed in oxidations of relatively simple substrates, often in excess to account for reagent trapping and decomposition. The use of adsorbents such as Celite or silica gel facilitates the removal of chromium byproducts and eliminates many of the operational difficulties associated with chromium mediated oxida ... more details
Zincke aldehydes , or 5 aminopenta 2,4 dienals , are the product of the reaction of a pyridinium salt with two equivalents of any secondary amine, followed by basic hydrolysis. Using secondary amines as opposed to primary amines the Zincke reaction takes on a different shape forming Zincke aldehydes in which the pyridine ring is ring opened with the terminal iminium group hydrolyzed to an aldehyde . The use of the dinitrophenyl group for pyridine activation was first reported by Theodor Zincke . ref cite journal title Ueber Dinitrophenylpyridiniumchlorid und dessen Umwandlungsproducte author Theodor Zincke Zincke, Th. Heuser, G. Moller, W. journal Justus Liebigs Annalen der Chemie volume 333 issue 2 3 pages 296 345 year 1904 url doi 10.1002 jlac.19043330212 ref ref cite journal title Ueber Dinitrophenylpyridiniumchlorid und dessen Umwandlungsproducte author Theodor Zincke Zincke, Th. Heuser, G. Moller, W. journal Justus Liebigs Annalen der Chemie volume 330 issue 2 pages 361 374 year 1904 url doi 10.1002 jlac.19043300217 ref ref cite journal title ber Dinitrophenylisochinoliniumchlorid und dessen Umwandlungsprodukte author Zincke, T. H. Weisspfenning, G. journal Justus Liebigs Annalen der Chemie volume 396 issue 1 pages 103 131 year 1913 url doi 10.1002 jlac.19133960107 ref The use of cyanogen bromide for pyridine activation was independently reported by W. K nig ref name Koenig cite journal author K nig, W. journal J. Prakt. Chem. volume 69 issue 1 title ber eine neue, vom Pyridin derivierende Klasse von Farbstoffen pages 105 137 year 1904 url doi 10.1002 prac.19040690107 ref Image ZinckeAldehyde.png 400px center Zincke aldehydes The synthesis and utility of Zincke aldehydes has been reviewed. ref cite journal title author Becher, J. journal Synthesis journal Synthesis volume issue pages 589 612 year 1980 url doi ref ref cite journal title Derivatives and reactions ... Heterocycles by the Ring Opening of Pyridinium Salts Aaron M. Kearney, Christopher D. Vanderwal ... more details
15 as reaction with Pyridinium tosylate PPTS and 2 methoxypropene gives the acetonide 16 . At this point ... alcohol group to the aldehyde 26 by Pyridinium chlorochromate PCC . class wikitable align center ... more details
Viologens are toxic bi pyridinium derivatives of 4,4 bipyridyl . ref GoldBookRef file V06624.html title viologens ref The name is because this class of compounds is easily organic reduction reduced to the radical ion radical mono cation , which is intensely blue colored. Possibly the best known viologen is paraquat , which is one of the world s most widely used herbicide s. Electrochemistry Viologens are also investigated for use in electrochromic systems because of their ability to change color reversibly many times upon Redox reduction and oxidation . In an experimental electrolysis setup, viologen in solution with sodium sulfate can be reduced at the cathode with simultaneous formation of hydrogen gas. Oxygen generated at the anode is capable of oxidizing the radical ion back to the viologen. Image Viologen.png 500px center Scheme 1. From left to right bipyridyl, viologen, radical ion and quinoid Further reduction yields a yellow Quinone quinoid compound. Diquaternary derivatives of 2,2 bipyridyl give a green radical anion. In extended viologens conjugated system conjugated oligomer s such as based on aryl , ethylene , and thiophene units are inserted between the pyridine units. ref cite journal author W. W. Porter, T. P. Vaid and A. L. Rheingold title Synthesis and Characterization of a Highly Reducing Neutral Extended Viologen and the Isostructural Hydrocarbon 4,4 Di n octyl p quaterphenyl year 2005 journal J. Am. Chem. Soc. volume 127 issue 47 pages 16559 16566 doi 10.1021 ja053084q pmid 16305245 ref The bipolaron di octyl bis 4 pyridyl biphenyl viologen 2 in scheme 2 can be reduced by sodium amalgam in dimethylformamide DMF to the neutral viologen 3 . Image Viologen reducing agent.png center 400 px Scheme 2. Viologen reducing agent The resonance structure s of the quinoid 3a and the biradical 3b contribute equally to the hybrid structure. The driving force for the contributing 3b is the restoration of aromaticity with the biphenyl unit. It has been established ... more details
Solvatochromism is the ability of a chemical substance to change color due to a change in solvent polar molecule polarity . Negative solvatochromism corresponds to hypsochromic shift blue shift with increasing solvent polarity and positive solvatochromism corresponds to bathochromic shift red shift with decreasing solvent polarity. The sign of the solvatochromism depends on the difference in Molecular dipole moment dipole moment between the ground and excited states of the chromophore . The Solvatochromic effect or solvatochromic shift refers to a strong dependence of UV VIS spectroscopy absorption and emission spectra with the solvent polar molecule polarity . Since polarities of the ground and excited state of a chromophore are different, a change in the solvent polarity will lead to differential stabilization of the ground and excited states, and thus, a change in the energy gap between these electronic states. Consequently, variations in the position, intensity, and shape of the absorption spectra can be direct measures of the specific interactions between the Solution solute and solvent molecules. Due to the Franck Condon principle atoms do not change position during light absorption , the excited state solvent shell is not in equilibrium with the excited state molecule solute . In fact, charge transfer transitions of ground state ion pairs give the largest changes in absorption spectra, and are thus, the most useful for measuring solvent polarity. An example of positive solvatochromism is the 4,4 bis dimethylamino fuchsone , which is orange in nonpolar toluene , red in slightly polar acetone , and red violet in more polar methanol . Examples of negative solvatochromism are 4 4 hydroxystyryl N methyl pyridinium iodide , which is red in 1 propanol , orange in methanol , and yellow in water . Charge transfer bands Charge transfer bands CT in electronic spectra Migration of an electron from an orbital that is predominantly metal in character to an orbital that is ... more details
Drugbox Verifiedfields changed verifiedrevid 447923576 IUPAC name 4 aminocarbonyl 1 6 R ,7 R 2 carboxy 8 oxo 7 phenyl sulfo acetyl amino 5 thia 1 azabicyclo 4.2.0 oct 2 en 3 yl methyl pyridinium image cefsulodin.png Clinical data tradename Drugs.com drugs.com international cefsulodin pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU Unscheduled S2 S3 S4 S5 S6 S7 S8 S9 legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL P POM CD Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CAS number Ref cascite correct ?? CAS number 52152 93 9 ATC prefix J01 ATC suffix DD03 PubChem 5284530 DrugBank Ref drugbankcite correct drugbank DrugBank ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 4447588 UNII Ref fdacite correct FDA UNII OV42LHE42B KEGG Ref keggcite correct kegg KEGG D02005 ChEMBL Ref ebicite changed EBI ChEMBL 1617285 Chemical data C 22 H 21 N 4 O 8 S 2 charge molecular weight 533.556 g mol smiles O C2N1 C C CS C H 1 C H 2NC O C c3ccccc3 S O O O C n 4ccc C O N cc4 C O O InChI 1 C22H20N4O8S2 c23 18 27 13 6 8 25 9 7 13 10 14 11 35 21 15 20 29 26 21 16 14 22 30 31 24 19 28 17 36 32,33 34 12 4 2 1 3 5 12 h1 9,15,17,21H,10 11H2, H4 ,23,24,27,28,30,31,32,33,34 t15 ,17?,21 m1 s1 InChIKey SYLKGLMBLAAGSC IKZMBGHXBW StdInChI Ref stdinchicite correct chemspider StdInChI 1S C22H20N4O8S2 c23 18 27 13 6 8 25 9 7 13 10 14 11 35 21 15 20 29 26 21 16 14 22 30 31 24 19 28 17 36 32,33 34 12 4 2 1 3 5 12 h1 9,15,17,21H,10 11H2, H4 ,23,24,27,28,30,31,32,33,34 t15 ,17?,21 m1 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey SYLKGLMBLAAGSC IKZMBGHXSA N Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa . It has no significant activity against other Gram negative bacteria and very limited activity ag ... more details
Cleavable detergents , also known as cleavable surfactants , are special surfactant s detergents that are used in biochemistry and especially in proteomics to enhance protein denaturation biochemistry denaturation and solubility. The detergent is rendered inactive by cleavage, usually under acid ic conditions, in order to make the sample compatible with a following procedure or in order to selectively remove the cleavage products. Applications for cleavable detergents include protease digestion of protein s such as in gel digestion with trypsin after SDS PAGE and peptide extractions from electrophoresis gels. Cleavable detergents are mainly used in sample preparations for mass spectrometry . PPS PPS , available as PPS Silent Surfactant from Protein Discovery , is the abbreviation for sodium 3 4 1,1 bis hexyloxy ethyl pyridinium 1 yl propane 1 sulfonate. This acetal ic detergent is split under acidic conditions into hexanol and the zwitterion ic 3 acetyl 1 3 sulfopropyl pyridinium . ref http www.proteindiscovery.com pages support faq pps.html PPS frequently asked questions the chemical structure on this site is wrong ref ref cite journal author Norris JL, Porter NA, Caprioli RM year 2003 title Mass spectrometry of intracellular and membrane proteins using cleavable detergents journal Anal. Chem. volume 75 issue 23 pages 6642 6647 pmid 14640740 doi 10.1021 ac034802z ref Image PPS cleavable detergent.png 250px PPA cleavable detergent math longrightarrow math 2 Image Hexanol chemical structure.png 100px math math Image 3 acetyl 1 3 sulfopropyl pyridinium.png 150px ProteaseMAX ProteaseMAX is the brandname of Promega for sodium 3 1 furan 2 yl undecyloxy carbonylamino propane 1 sulfonate. This cleavable detergent is sensitive to heat and acid and is degraded during a typical trypsin digestion into the uncharged lipophilic compound 1 furan 2 yl undecan 1 ol and the zwitterion ic 3 aminopropane 1 sulfonic acid homotaurine , which can be removed by C18 solid phase extraction ... more details
Chembox Watchedfields changed verifiedrevid 431382949 ImageFile 2,6 Pyridinedicarbothioicacid.svg ImageSize ImageAlt IUPACName 2,6 pyridinedicarbothioic acid OtherNames PDTC, dithiopyridinedicarbothioic acid Section1 Chembox Identifiers CASNo 69945 42 2 PubChem 25202662 SMILES C1 CC NC C1 C O S C O S PubChem 10214455 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 8389947 SMILES O C S c1nc C O S ccc1 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C7H5NO2S2 c9 6 11 4 2 1 3 5 8 4 7 10 12 h1 3H, H,9,11 H,10,12 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey SSRIAMRLMUFTNV UHFFFAOYSA N Section2 Chembox Properties C 7 H 5 O 2 S 2 Appearance White crystalline solid Density 1.415 g cm sup 3 sup MeltingPtCL 97 MeltingPtCH 99 BoilingPtC 404.4 Solubility 1000 g L 5.02 mol L Section3 Chembox Hazards MainHazards acidic FlashPt convert 198.4 C F Autoignition 2,6 Pyridinedicarbothioic acid PDTC is an organosulfur compound that is produced by some bacteria. It functions as a siderophore , a small chelating agent with a high affinity for iron . Siderophores are deployed as ion scavengers for microbes . Siderophores solubilize compounds by forming strong complexes. PDTC is secreted by the soil bacteria Pseudomonas stutzeri and Pseudomonas putida . ref cite journal doi 10.1007 978 3 211 99661 4 1 title Microbial Siderophores year 2010 last1 Budzikiewicz first1 Herbert volume 92 pages 1 75 ref Synthesis and biosynthesis PDTC can be synthesized by treating the pyridine 2,6 dicarboxylic acid or its diacid dichloride with H sub 2 sub S in dry pyridine NC sub 5 sub H sub 3 sub COOH sub 2 sub 2 H sub 2 sub S NC sub 5 sub H sub 3 sub COSH sub 2 sub 2 H sub 2 sub O This produces an orange 1 1 pyridinium salt of 2,6 pyridinedicarbothioate. Treatment of this salt with acid give PDTC, which can then be extracted with dichloromethane . The biosynthesis of PDTC remains unclear although some insights can be deduced from the genetics. ref cite journal doi 10.11 ... more details
to other oxidation methods such as Pyridinium chlorochromate PCC and Dess Martin periodinane is that secondary ... Meerwein Ponndorf Verley reduction Dess Martin oxidation Pyridinium chlorochromate PCC Jones oxidation ... more details
ref Structure & reactivity Cephaloridine is a cephalosporin compound with pyridinium 1 ylmethyl and 2 .... The cationic group pyridinium ring of the compound probably inhibits the efflux through ... due to the unstable lactam ring. ref name Timbrell The pyridinium side group of cephaloridine ... . The pyridinium side group interacts with the reduced NADP in a redox cycle. It has been suggested ... more details
Reagents He has developed several new synthetic reagents pyridinium chlorochromate PCC pyridinium chlorochromate , also referred to as the Corey Suggs reagent , and PDC pyridinium dichromate widely used for the oxidation of alcohol s to aldehyde s. ref Corey, E.J., and Suggs, W. Pyridinium Chlorochromate ... more details
Refimprove article date June 2010 Drugbox verifiedrevid 464212974 IUPAC name 2 hydroxyimino methyl 1 methylpyridin 1 ium image Pralidoxime 2D skeletal.png width 200 image2 Pralidoxime 3D vdW.png Clinical data tradename Drugs.com drugs.com CONS pralidoxime pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category C legal AU Unscheduled S2 S4 S8 legal UK GSL P POM CD legal US OTC Rx only legal status RX only Identifiers CASNo Ref cascite correct CAS CAS number Ref cascite correct ?? CAS number 6735 59 7 ATC prefix V03 ATC suffix AB04 PubChem 6789253 DrugBank Ref drugbankcite correct drugbank DrugBank DB00733 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 5193737 UNII Ref fdacite correct FDA UNII P7MU9UTP52 KEGG Ref keggcite correct kegg KEGG C07400 ChEBI Ref ebicite correct EBI ChEBI 8354 ChEMBL Ref ebicite correct EBI ChEMBL 1420 Chemical data C 7 H 9 N 2 O 1 charge molecular weight 137.159 g mol smiles O NH C C1 C C C C N1C InChI 1 C7H8N2O c1 9 5 3 2 4 7 9 6 8 10 h2 6H,1H3 p 1 InChIKey JBKPUQTUERUYQE IKLDFBCSAA StdInChI Ref stdinchicite correct chemspider StdInChI 1S C7H8N2O c1 9 5 3 2 4 7 9 6 8 10 h2 6H,1H3 p 1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey JBKPUQTUERUYQE UHFFFAOYSA O synonyms small 1 methylpyridine 6 carbaldehyde oxime small Pralidoxime 2 pyridine aldoxime methyl chloride, or 2 PAM , usually as the chloride or methiodide salts, belongs to a family of compounds called oxime s that bind to organophosphate inactivated acetylcholinesterase . It is used to combat Organophosphate poisoning poisoning by organophosphates ref name pmid19519385 cite journal author Jokanovi M, Prostran M title Pyridinium oximes as cholinesterase reactivators. Structure activity relationship and efficacy in the treatment of poisoning with organophosphorus compounds journal Curr. Med. Chem. volume 16 issue 17 pages 2177 88 year 2009 pmid 19519385 doi 10.2174 092986709788612729 url http www.bentham direct.org pages content.php?CMC 20 ... more details
reduction and pyridinium chlorochromate oxidation of 21 forms the aldehyde 22 . A second Norrish reaction ... in several steps a Birch reduction to diol 24 , oxidation with pyridinium chlorochromate to ketoaldehyde ... more details
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