- Bropirimine
Drugbox verifiedrevid IUPAC name 2 amino 5 bromo 6 phenylpyrimidin 4 1H one image Bropirimine structure.png Clinical data tradename pregnancy category legal status routes of administration Pharmacokinetic data bioavailability metabolism excretion Identifiers CASNo Ref cascite CAS number 56741 95 8 ATC suffix DrugBank ChemSpiderID 58914 UNII Ref fdacite correct FDA UNII J57CTF25XJ Chemical data C 10 H 8 Br 1 N 3 O 1 molecular weight 266.09 g mol smiles Br C2 C c1ccccc1 N C N C2 O N synonyms Bropirimine is an experimental drug with anti cancer and anti viral properties. ref http www.sciencedirect.com science? ob ArticleURL& udi B6WXH 4DBJKXX B2& user 10& rdoc 1& fmt & orig search& sort d& docanchor &view c& searchStrId 961628678& rerunOrigin google& acct C000050221& version 1& urlVersion 0& userid 10&md5 2153a0f206ac03596861c249369d347d ref It is an orally effective immunomodulator and is being tried in bladder cancers. ref http content.karger.com ProdukteDB produkte.asp?Doi 19693 ref Chemistry File Bropirimine synthesis.png 500px Cite journal doi 10.1021 jm00150a018 title Pyrimidinones. 1. 2 Amino 5 halo 6 aryl 4 3H pyrimidinones. Interferon inducing antiviral agents pmid 2999405 year 1985 last1 Skulnick first1 Harvey I. last2 Weed first2 Sheldon D. last3 Eidson first3 Emerson E. last4 Renis first4 Harold E. last5 Stringfellow first5 Dale A. last6 Wierenga first6 Wendell journal Journal of Medicinal Chemistry volume 28 issue 12 pages 1864 9 References reflist Category Experimental cancer drugs Category Pyrimidones Category Organobromides antineoplastic drug stub ... more details
|
- Phosphonium coupling
rich pyrimidinones and amino acids promoted by phosphonium salts, Organic & Biomolecular Chemistry ... more details
|
- List of MeSH codes (D03)
Pyrimethamine pyrimethamine MeshNumber D03.383.742.698 Pyrimidinones pyrimidinones MeshNumber ... more details
|
Encyclopedia
top
