Drugbox verifiedrevid 449870661 IUPAC name 1 1 methyl 3,3 di 2 thienylprop 2 en 1 yl pyrrolidine image Pyrrolidinylthiambutene.png width 180 Clinical data tradename pregnancy AU pregnancy US pregnancy category legal AU legal CA legal US legal status routes of administration Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CAS number ATC prefix none ATC suffix PubChem Chemical data C 16 H 19 N 1 S 2 molecular weight 289.458 g mol smiles C2CCCN2C C C C c1sccc1 c3sccc3 melting point 167 melting high 169 Pyrrolidinylthiambutene is an opioid analgesic drug from the thiambutene family with around 3 4 of the potency of morphine . ref Adamson DW, Green AF. A new series of analgesics. Nature . 1950 Jan 21 165 4186 122. DOI 10.1038 165122a0 PMID 15409854 ref ref Adamson DW, Duffin WM, Green AF. Dithienylbutylamines as analgesics. Nature . 1951 Jan 27 167 4239 153 4. DOI 10.1038 167153b0 PMID 14806409 ref ref Green AF. Analgesic and other properties of 3 3 dithienylalkenylamines. British Journal of Pharmacology and Chemotherapy . 1953 Mar 8 1 2 9. PMID 13066683 ref It would be considered an illegal Federal Analog Act controlled substance analogue in some countries such as the USA, Australia and New Zealand, but is legal in countries not possessing a controlled substances analog act equivalent. References references Opioids Category Opioids Category Thiophenes Category Pyrrolidines Category Mu opioid agonists analgesic stub ... more details
Here is a table skip past it to edit the text class wikitable style float right margin 0 0 0.5em 1em text align center font size smaller Endogenous opioid peptides Skeletal molecular images Adrenorphin Image Adrenorphin.png 125 px Chemical structure of Adrenorphin Amidorphin Image Amidorphin.png 125 px Chemical structure of Amidorphin. Casomorphin Image Bovine casomorphin 7.png 125 px Chemical structure of Bovine casomorphin. DADLE Image 2 D Alanine 5 D leucine enkephalin.png 125 px Chemical structure of DADLE. DAMGO Image DAMGO.png 125 px Chemical structure of DAMGO. Dermorphin Image Dermorphin.svg 125 px Chemical structure of Dermorphin. Endomorphin Image Endomorphin 1.svg 125 px Chemical structure of Endomorphin 1. Morphiceptin Image Morphiceptin.svg 125 px Chemical structure of Morphiceptin. Nociceptin Image Nociceptin.png 125 px Chemical structure of Nociceptin. Octreotide Image Octreotide.svg 125 px Chemical structure of Octreotide. Opiorphin Image Opiorphin.png 125 px Chemical structure of Opiorphin. TRIMU 5 Image TRIMU 5.png 125 px Chemical structure of TRIMU 5. End of the table An opioid is a psychoactive chemical that works by binding to opioid receptor s, which are found principally in the central nervous system central and peripheral nervous system and the gastrointestinal tract . The receptors in these organ systems mediate both the beneficial effects and the adverse effect side effects of opioids. Opioids are among the world s oldest known drug s the use of the opium poppy for its therapeutic benefits predates recorded history. The analgesic painkiller effects of opioids are due to decreased perception of pain, decreased reaction to pain as well as increased pain tolerance. The side effects of opioids include sedation , respiratory depression , constipation , and a strong sense of euphoria . Opioids can cause cough suppression, which can be both an indication for opioid administration or an unintended side effect. Opioid dependence can develop with ... more details
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