- Quinacrine
pentane 1,4 diamine image Quinacrine.svg width 200 imagename 1 1 mixture racemate drug name Quinacrine Clinical data tradename Atabrine Drugs.com drugs.com CONS quinacrine Pharmacokinetic data ... chemspider StdInChIKey GPKJTRJOBQGKQK UHFFFAOYSA N Quinacrine trade name Atabrine is a medication ... name drugsdotcom http www.drugs.com mmx quinacrine hydrochloride.html Drugs.com Quinacrine. Retrieved on August 24, 2009 ref Antiprotozoal use include targeting Giardiasis , where quinacrine is indicated ... a combination of quinacrine and metronidazole. ref name drugsdotcom Quinacrine is also used off label ... activating factor levels following quinacrine add on therapy in systemic lupus erythematosus journal ..., cystic fibrosis patients. ref name drugsdotcom Quinacrine is not the drug of choice because side effects ... information. In addition to medical applications, quinacrine is an effective in vitro research tool for the epifluorescent visualization of cells, especially platelets. Quinacrine is a green fluorescent dye taken up by most cells. Platelet store quinacrine in dense granules. Mechanism Its mechanism ... and activates p53 . History of uses Antiprotozoal Quinacrine was initially approved in the 1930s as an antimalarial ... P title Randomized clinical study of five days apostrophe therapy with mebendazole compared to quinacrine ... of phospholipase A2 . Scientists at Bayer in Germany first synthesised Quinacrine in 1931 and subsequently ... tapeworm infections. ref DorlandsDict nine 000956295 quinacrine ref Creutzfeldt Jakob disease Quinacrine has been shown to bind to the prion protein and prevent the formation of prion aggregates ... K, Tanaka H, Yamada T title Quinacrine administration to a patient with Creutzfeldt Jakob disease who ... use of quinacrine in Creutzfeldt Jakob disease fails to show significant effects journal ... G, Auvr F, Adjou K, Sal s N, Williams A, Lasm zas C, Deslys J title Evaluation of Quinacrine ... N, Vigui C, Laroute V, Andr oletti O, Toutain P title A possible pharmacological explanation for quinacrine ... more details
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- Anticestodal agent
An anticestodal agent is a drug used to combat tapeworm infection . ref MeshName Anticestodal agents ref It derives its name from Cestoda . Examples include ref MeshPharmaList 82000923 ref albendazole albendazole sulfoxide dichlorophen niclosamide quinacrine References reflist Anthelmintics Category Antiparasitic agents antiinfective drug stub ... more details
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- Stephen Douglas Mumford
date June 19, 1998 . ref and has been involved in the international distribution of quinacrine to developing countries for sterilizing women there. ref citation title Govt drags feet on quinacrine threat ... res web pIe ie daily 19980725 20650684.html . ref ref citation title Quinacrine s vast appeal, considerable ... more details
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- Sterilization (medicine)
http linkinghub.elsevier.com retrieve pii S0020 7292 09 00399 3 ref Quinacrine has also been used for transluminal sterilization, but despite a multitude of clinical studies on the use of quinacrine ... controversy over its use. ref name drugsdotcom http www.drugs.com mmx quinacrine hydrochloride.html Drugs.com Quinacrine. Retrieved on August 24, 2009 ref Pharmacological There is no working sterilization ... more details
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- National Prion Clinic (UK)
J. A partially randomised patient preference trial to assess the safety and activity of quinacrine ... quinacrine . ref name ReferenceA Currently 2010 the NPC is recruiting into the National Prion ... more details
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- Metaphase
. Staining of the slides, often with Giemsa G banding or Quinacrine , produces a pattern of in total ... more details
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- Michael Homer
and bovine spongiform encephalopathy mad cow disease . The team at UCSF was studying the use of Quinacrine ... more details
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- Janet Rowley
developed the use of existing methods of quinacrine fluorescence and Giemsa staining to identify chromosome ... more details
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- Intercalation (chemistry)
sub , acridine s such as proflavine or quinacrine , or ethidium bromide. Intercalation as a mechanism ... more details
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- Torbjörn Caspersson
when working at the Karolinska Institute , he with Lore Zech found that a stain quinacrine mustard ... more details
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- Karyotype
pattern obtained using quinacrine for staining. The pattern of bands is very similar to that seen ... , often Giemsa G banding , less frequently Quinacrine , is used to stain bands on the chromosomes. Giemsa is specific for the phosphate groups of DNA . Quinacrine binds to the adenine thymine rich ... more details
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- Giardiasis
. ref name gardner treatment Quinacrine Adult dosage 100 mg three times a day for 5 days ref name drugs ... the drug because quinacrine can cross the placenta and might cause spina bifida and renal agenesis in the infant ... have developed resistance to all of the common anti giardial drugs, such as metronidazole, quinacrine ..., such as metronidazole albendazole and metronidazole quinacrine. ref name gardner treatment Lab diagnosis ... more details
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- Philadelphia chromosome
myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining journal Nature ... more details
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- Protein Misfolding Cyclic Amplification
Evaluation of quinacrine treatment for prion diseases. J Virol 77, 8462 8469. ref ref Haley, N.J. ... more details
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- Cytogenetics
are used in cytogenetics laboratories. Quinacrine banding Q banding was the first staining ... more details
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- List of MeSH codes (D03)
For other categories, see List of MeSH codes . This is the fourth part of the list of the D codes for MeSH . It is a product of the United States National Library of Medicine . Source for content is http www.nlm.nih.gov mesh filelist.html here . File 2006 MeSH Trees . MeshNumber D03 Heterocyclic Compounds heterocyclic compounds MeshNumber D03.066 Acids, Heterocyclic acids, heterocyclic MeshNumber D03.066.160 Cinoxacin cinoxacin MeshNumber D03.066.288 Indoleacetic Acids indoleacetic acids MeshNumber D03.066.288.200 Etodolac etodolac MeshNumber D03.066.288.478 Hydroxyindoleacetic Acid hydroxyindoleacetic acid MeshNumber D03.066.349 Isonicotinic Acids isonicotinic acids MeshNumber D03.066.349.220 Ethionamide ethionamide MeshNumber D03.066.349.390 Iproniazid iproniazid MeshNumber D03.066.349.410 Isoniazid isoniazid MeshNumber D03.066.349.490 Nialamide nialamide MeshNumber D03.066.349.570 Prothionamide prothionamide MeshNumber D03.066.349.600 Pyridoxic Acid pyridoxic acid MeshNumber D03.066.399 Isonipecotic Acids isonipecotic acids MeshNumber D03.066.399.300 Diphenoxylate diphenoxylate MeshNumber D03.066.399.450 Meperidine meperidine MeshNumber D03.066.399.450.700 Promedol promedol MeshNumber D03.066.399.600 Phenoperidine phenoperidine MeshNumber D03.066.399.650 Pirinitramide pirinitramide MeshNumber D03.066.515 Nicotinic Acids nicotinic acids MeshNumber D03.066.515.292 Arecoline arecoline MeshNumber D03.066.515.375 Clonixin clonixin MeshNumber D03.066.515.400 Etazolate etazolate MeshNumber D03.066.515.475 Niacin niacin MeshNumber D03.066.515.530 Niacinamide niacinamide MeshNumber D03.066.515.530.248 6 Aminonicotinamide 6 aminonicotinamide MeshNumber D03.066.515.530.498 Nicorandil nicorandil MeshNumber D03.066.515.530.500 Nikethamide nikethamide MeshNumber D03.066.515.540 Niceritrol niceritrol MeshNumber D03.066.515.550 Niflumic Acid niflumic acid MeshNumber D03.066.515.635 Pipemidic Acid pipemidic acid MeshNumber D03.066.515.650 Piromidic Acid piromidic acid MeshNumber ... more details
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- Pro-Vas Occlusion
Ngoc first4 DH last5 Duong first5 LQ title The acceptability, efficacy and safety of quinacrine ... more details
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- Creutzfeldt?Jakob disease
cjd research current quinacrine treatment trial for sporadic CJD using quinacrine , a medicine originally created for malaria. Pilot studies showed quinacrine permanently cleared abnormal prion proteins ... more details
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- Enzyme inhibitor
1989 pmid 2553730 ref Examples of irreversible inhibitors File Quinacrine mustard in Trypanothione ... from the human protozoan parasite Trypanosoma cruzi , two molecules of an inhibitor called quinacrine ... for quinacrine derivatives in the active site of trypanothione reductase a template for drug design ... more details
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- Neil Hamilton Fairley
, patients with relapses were treated with intravenous quinine for three days followed by a course of quinacrine ... sulfonamide medicine sulphonamides , ref harvnb Sweeney 2003 pp 53 58,64 65 ref Quinacrine atebrin , ref ... more details
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- Johan Sebastiaan Ploem
of quinacrine mustard or quinacrine stained chromosomes. Histochemie 33 61 70, 1973. br Ploem, J ... more details
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- Conductive polymer
thin films of acridine orange and quinacrine. In 1960, researchers at Dow Chemical developed AC driven ... more details
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- Wyeth
wartime drugs such as sulfa bacteriostatics, blood plasma , typhus vaccine, quinine , and Quinacrine ... more details
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- XYY syndrome
of the Y chromosome in the nuclei of metaphase cells treated with quinacrine mustard. ref name Zech ... cells in buccal smears treated with quinacrine dihydrochloride, which could be used to screen for Y ... more details
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- List of MeSH codes (D02)
For other categories, see List of MeSH codes . This is the fourth part of the list of the D codes for MeSH . It is a product of the United States National Library of Medicine . Source for content is http www.nlm.nih.gov mesh filelist.html here . File 2006 MeSH Trees . MeshNumber D02 Organic Chemicals organic chemical s MeshNumber D02.033 Alcohols alcohol s MeshNumber D02.033.100 Amino Alcohols amino alcohol s MeshNumber D02.033.100.291 Ethanolamines ethanolamine s MeshNumber D02.033.100.291.057 Albuterol salbutamol albuterol MeshNumber D02.033.100.291.211 Choline choline MeshNumber D02.033.100.291.211.500 Platelet Activating Factor platelet activating factor MeshNumber D02.033.100.291.231 Clenbuterol clenbuterol MeshNumber D02.033.100.291.274 Deanol deanol MeshNumber D02.033.100.291.310 Epinephrine epinephrine MeshNumber D02.033.100.291.375 Ethanolamine ethanolamine MeshNumber D02.033.100.291.410 2 Hydroxyphenethylamine 2 hydroxyphenethylamine MeshNumber D02.033.100.291.439 Isoproterenol isoproterenol MeshNumber D02.033.100.291.460 Labetalol labetalol MeshNumber D02.033.100.291.480 Midodrine midodrine MeshNumber D02.033.100.291.502 Norepinephrine norepinephrine MeshNumber D02.033.100.291.502.651 Normetanephrine normetanephrine MeshNumber D02.033.100.291.525 Octopamine octopamine MeshNumber D02.033.100.291.550 Orciprenaline orciprenaline MeshNumber D02.033.100.291.550.300 Fenoterol fenoterol MeshNumber D02.033.100.291.617 Phenylephrine phenylephrine MeshNumber D02.033.100.291.617.300 Etilefrine etilefrine MeshNumber D02.033.100.291.630 Procaterol procaterol MeshNumber D02.033.100.291.805 Sotalol sotalol MeshNumber D02.033.100.291.870 Synephrine synephrine MeshNumber D02.033.100.291.905 Terbutaline terbutaline MeshNumber D02.033.100.350 Heptaminol heptaminol MeshNumber D02.033.100.400 Isoetharine isoetharine MeshNumber D02.033.100.624 Propanolamines propanolamines MeshNumber D02.033.100.624.025 Acebutolol acebutolol MeshNumber D02.033.100.624.058 Alprenolol alprenolol ... more details
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