PBB geneid 6144 60S ribosomal protein L21 is a protein that in humans is encoded by the RPL21 gene . ref name pmid3459254 cite journal author Nakamichi NN, Kao FT, Wasmuth J, Roufa DJ title Ribosomal protein gene sequences map to human chromosomes 5, 8, and 17 journal Somat Cell Mol Genet volume 12 issue 3 pages 225 36 year 1986 month Jul pmid 3459254 pmc doi 10.1007 BF01570781 ref ref name pmid7772601 cite journal author Frigerio JM, Dagorn JC, Iovanna JL title Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs journal Biochim Biophys Acta volume 1262 issue 1 pages 64 8 year 1995 month Jul pmid 7772601 pmc doi ref ref name entrez cite web title Entrez Gene RPL21 ribosomal protein L21 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6144 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L21E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. ref name entrez Clinical relevance Mutations in the RPL21 gene result in Hypertrichosis simplex of the scalp . ref name pmid21412954 cite journal pmid 21412954 doi 10.1002 humu.21503 title Mutation in ribosomal protein L21 underlies hereditary hypotrichosis simplex year 2011 month March author Zhou C author separator , author2 Zang D author3 Jin Y display authors 3 last4 Wu first4 Huafeng last5 Liu first5 Zhengyi last6 Du first6 Juan last7 Zhang first7 ... more details
60S is the large ribosomal subunit in eukaryotes . ref MeshName 60S Ribosome Subunits ref It corresponds to 50S in prokaryote s. It consists of the following 5S ribosomal RNA 5S 28S 5.8S The following is a list of proteins contained within the 60S ribosome class wikitable Gene Protein RPL4 ribosomal protein L4 RPL7A ribosomal protein L7a RPL14 ribosomal protein L14 RPL18 ribosomal protein L18 RPL18A ribosomal protein L18a RPL19 ribosomal protein L19 RPL21 ribosomal protein L21 RPL27 ribosomal protein L27 RPL28 ribosomal protein L28 RPL29 ribosomal protein L29 RPL35 ribosomal protein L35 RPL37 ribosomal protein L37 RPLP2 ribosomal protein, large, P2 References reflist Ribosome subunits Category Ribosomal RNA biochem stub ca 60S ... more details
Encyclopedia
top
