Similarity Matrix of Proteins , or SIMAP , is a database of protein similarities created using distributed computing, which is freely accessible for scientific purposes. SIMAP uses the FASTA algorithm to precalculate protein similarity, while another application uses hidden Markov model s to search for Protein domain s. SIMAP is a joint project of the Technical University of Munich , the Helmholtz Zentrum M nchen , and the University of Vienna . The project usually gets new work units at the beginning of each month. More recently, 2010 , inclusion of environmental sequences into the database has required longer periods of activity, several months of continuous work for example. Typically, these updates occur twice each year. In the fourth quarter of 2010, the project relocated to the University of Vienna due to the failing electrical infrastructure at the Technical University of Munich ref http boincsimap.org boincsimap old news.php ref . Part of this exercise involved the creation of a project specific URL requiring existing volunteers and users to detach reattach to the project. Computing platform SIMAP uses the Berkeley Open Infrastructure for Network Computing BOINC distributed ... around 1.20 MB. SIMAP provides client software optimized for Streaming SIMD Extensions SSE enabled ... manual installation steps to be taken. Operating Systems supported by SIMAP are Linux , Microsoft Windows ... for SIMAP. See also Grid computing Protein Rosetta home Predictor home Folding home BOINC References reflist External links http boincsimap.org boincsimap SIMAP Website http webclu.bio.wzw.tum.de portal web simapSIMAP Database Search http allprojectstats.com top.php?s 0&o 0&projekt 5&type 1 SIMAP project stats BOINC topics Category Berkeley Open Infrastructure for Network Computing projects Science software stub cs SIMAP de SIMAP es SIMAP fr Similarity Matrix of Proteins it SIMAP ja SIMAP ru SIMAP home zh SIMAP ... more details
Sindicato de M dicos de Asistencia P blica , the Spanish doctors union, started on 22 August 1991, under the acronym SIMAP CV . SIMAP is a union of doctors working in public health. Since its foundation has been involved in various initiatives to protect public health and the rights of physicians. This union achieved notoriety by being the promoter of the SIMAP case before the European Court of Justice , referring to the working time of physicians. The SIMAP case also known as Sindicato de M dicos de Asistencia P blica v Conselleria de Sanidad y Consumo de la Generalidad Valenciana ref cite web url http eur lex.europa.eu LexUriServ LexUriServ.do?uri CELEX 61998J0303 EN HTML title European Court of Justice Sindicato de Medicos de Asistencia Publica v Conselleria de Sanidad y Consumo de la Generalidad Valenciana ref is a European labour law and UK labour law case concerning the Working Time Directive , which is relevant for the Working Time Regulations 1998 . At the European level, the SIMAP case had a significant impact ref cite web url http www.publications.parliament.uk pa ld200304 ldselect ldeucom 67 6706.htm title Select Committee on European Union ninth report The impact of SiMAP and Jaeger European Court of Justice Judgements. 2006. ref in the regulation of working time and the implementation of Working Time Directive . A recent editorial in the British Medical Journal ref cite web url http www.bmj.com content 341 bmj.c6034.full title Goddard AF. Planning a consultant delivered NHS.BMJ 2010 341 c6034 ref raises reversing the SiMAP and Jaeger rulings, renegotiating the new deal, relaxing immigration rules, and enhancing mobility between specialties will all give the NHS more flexibility to cope with its ever increasing demands. Notes reflist External links official website http www.simap.es DEFAULTSORT Sindicato De Medicos De Asistencia Publica Simap Category Trade unions in Spain es Sindicato de M dicos de Asistencia P blica ... more details
Carolyn Allison Rodrigues Birkett born September 16 1973 ref name Meet http www.gina.gov.gy booklets cabinet.pdf Meet the New Cabinet Members , GINA. ref is a Guyana Guyanese politician who has served as Minister of Foreign Affairs since April 2008. ref name FM http www.gina.gov.gy archive daily b080409.html Rodrigues appointed Foreign Affairs Minister , GINA, April 9, 2008. ref Rodrigues, an Amerindian , ref name IBD David Mangurian, http www.iadb.org idbamerica English JUL01E jul01e1.html The Iron Woman of Guyana , IBDAmerica, August 2001. ref was born in Moruca , Barima Waini Barima Waini Region . After attending a private school in Georgetown, Guyana Georgetown , ref name Meet she received a scholarship for Amerindians ref name IBD and went to study business administration at the University of Regina in Canada and returned to Guyana in 1993. ref name Meet She was required by her scholarship to work for Amerindian communities, and as a result she left the lumber company where she worked and instead went to work for the Inter American Development Bank s Social Impact Amelioration Programme SIMAP in Guyana, although this meant 65 less pay. ref name IBD She became Coordinator of SIMAP s Amerindian Projects Programme, holding that post until 2001, when went to study in social work at the University of Guyana . ref name Meet Rodrigues was appointed to the Cabinet as Minister of Amerindian Affairs in April 2001. Following the Guyanese general election, 2006 2006 general election , she was reappointed as Minister of Amerindian Affairs and sworn in on September 4, 2006 ref http www.gina.gov.gy archive daily b060904.html President swears in first two Ministers , GINA, September 4, 2006. ref After seven years as Minister of Amerindian Affairs, she was appointed as Minister of Foreign Affairs on April 9, 2008, replacing Rudy Insanally . ref name FM She was sworn in on April 10. ref http www.gina.gov.gy archive daily b080410.html Two new Ministers sworn in before President J ... more details
Infobox Court Case name SIMAP v CSCGV court European Court of Justice image date decided full name citations 2000 http eur lex.europa.eu LexUriServ LexUriServ.do?uri CELEX 61998J0303 EN HTML C 303 98 , 2000 ECR I 7963 judges prior actions subsequent actions opinions transcripts keywords Working Time Directive Sindicato de Medicos de Asistencia Publica v Conselleria de Sanidad y Consumo de la Generalidad Valenciana 2000 http eur lex.europa.eu LexUriServ LexUriServ.do?uri CELEX 61998J0303 EN HTML C 303 98 is a European labour law and UK labour law case concerning the Working Time Directive , which is relevant for the Working Time Regulations 1998 . Facts The Spanish legislation that implemented the Working Time Directive applied only to private sector workers. The question was if Spanish doctors in the Sindicato de M dicos de Asistencia P blica were engaged in public sector work described as in regulation 18 2 a now updated through Article 17 , which gave examples of the armed forces and police. Judgment The European Court of Justice held that health care workers could not be assimilated to such activities to fall within the exception for essential public sector workers like the armed forces. According to the general principles of construction, it is clear both from the object of the basic Directive, namely to encourage improvement in the safety and health of workers at work, and from the wording of Article 2 1 thereof, that it must necessarily be broad in scope. It follows that the exceptions to the scope of the basic Directive, including that provided for in Article 1 3 must be interpreted restrictively. This meant that time doctors spent on call where they were obliged to respond to requests for home visits and urgent requests was working time and so time going over the 48 hour ceiling violated the Directive. Cquote As the Advocate General also states in point 37 of his ... law Category 2000 in case law Category 2000 in Spain es Caso Simap ... more details
Peptide sequence or amino acid sequence is the order in which amino acid residues, connected by peptide bond s, lie in the chain in peptide s and protein s . The sequence is generally reported from the N terminal end containing free amino group to the C terminal end containing free carboxyl group . Peptide sequence is often called protein sequence if it represents the primary structure of a protein . Sequence notation and applications Many peptide sequences have been in sequence database s. These databases may use various notations to describe the peptide sequence. The full names of the amino acids are rarely given instead, Amino acid Table of standard amino acid abbreviations and properties 3 letter or 1 letter abbreviations are usually recorded for conciseness. Several deductions can be made from the sequence itself. Long stretches of hydrophobic residues may indicate transmembrane helix transmembrane helices . These helices may indicate the peptide is a cell receptor . Certain residues indicate a beta sheet area. If full length protein sequence is available, it is possible to estimate the isoelectric point of the protein. Methods for determining the peptide sequence include deduction from DNA sequence, Edman degradation , and mass spectrometry . Techniques in sequence analysis can be applied to learn more about the peptide. These techniques generally consist of comparing the sequence to other sequences from sequence databases. Other sequences may have already been studied and determined to be significant. Findings about these sequences may be applicable to the sequence under investigation. See also Protein Protein sequencing Rosetta home SIMAP External links http www.nslij genetics.org dnacorr A bibliography on features, patterns, correlations in DNA and protein texts Category Protein structure Category Bioinformatics de Aminos uresequenz el es Secuencia de amino cidos eo Aminoacida sinsekvo ko it Sequenza peptidica pt Sequ ncia pept d ... more details
Infobox Court Case name Landeshauptstadt Kiel v Jaegar court European Court of Justice image date decided 9 September 2003 full name citations 2003 http eur lex.europa.eu LexUriServ LexUriServ.do?uri CELEX 62002J0151 EN HTML C 151 02 , 2003 ECR I 08389 judges prior actions subsequent actions opinions transcripts keywords Working Time Directive Landeshauptstadt Kiel v Jaegar 2003 http eur lex.europa.eu LexUriServ LexUriServ.do?uri CELEX 62002J0151 EN HTML C 151 02 is a European labour law and UK labour law case concerning the Working Time Directive , which is relevant for the Working Time Regulations 1998 . Facts A doctor remained on call between shifts and was given a room to sleep in at the hospital. The collective agreement said the average time working when on call periods between 16 and 25 hours should not exceed 49 of the on call period. Dr Jaeger argued that all on call time should be regarded as working time. The Bundesarbeitsgericht asked for a preliminary ruling, asking whether under art 3 and art 6 of 93 104 EC time spent on call was working time as implemented by the Law on Working Time 1994 5 III in Germany . The law said Dr Jaeger had to stay at work, but could sleep there if not required to work. On average, Dr Jaeger did spend 49 of his time on call. The time spent inactive was deemed to be a rest period. Judgment The European Court of Justice held that all time he was required to be at the hospital, even when sleeping, was to be regarded as working time. The Directive, after the Sindicato de M dicos de Asistencia P blica v Conselleria de Sanidad y Consumo de la Generalidad Valenciana SIMAP case ref http eur lex.europa.eu LexUriServ LexUriServ.do?uri CELEX 61998J0303 EN HTML Case C 303 98 ref could not be taken to treat inactive on call time as a rest period. Dr Jaeger, by being required to stay at work was subject to greater constraints than a doctor at home, because he was kept apart from his family and social environment. The 1994 Act breached the ... more details
that the European Court of Justice decision on the Working Time Directive in SIMAP provided some .... In SIMAP the doctors were on call but at home, a place where, on any view, they did no work ... more details
Infobox mountain name Mount Iwaki other name photo Iwakisan 02.jpg photo caption Mount Iwaki and apple orchard elevation m 1624.7 elevation ref prominence prominence ref map Japan map caption map size 280 label position listing List of mountains and hills of Japan by height br List of volcanoes in Japan location Aomori Prefecture , Japan range lat d 40 lat m 39 lat s 12 lat NS N long d 140 long m 18 long s 24 long EW E topo type Stratovolcano age volcanic arc belt last eruption 1863 first ascent easiest route nihongo Mount Iwaki Iwaki san is a stratovolcano located in western Aomori Prefecture , Tohoku , Japan . It is also referred to as Tsugaru Fuji from its shape. ref cite gvp vnum 0803 27 name Iwaki ref the mountain is listed as one of the 100 Famous Japanese Mountains in a book composed in 1964 by Mountaineering mountaineer author Ky ya Fukada . ref name hyakumeizan http www.japangazetteer.com Hyakumeizan, Hiking Japan . Japan Gazetteer. Accessed June 27, 2008. ref The mountain and its surroundings are located within the borders of Tsugaru Quasi National Park . Geology Mount Iwaki is a roughly symmetrical andesitic stratovolcano, rising in relative isolation from the plains at the base of Tsugaru Peninsula . Its summit crater is two kilometers wide, and it has three lava dome s on the western and southern flanks. The mountain has frequently been active in historic times, with very frequent activity consisting mostly of small to moderate phreatic explosions during the Edo period . The last known eruption was on March 23, 1863. Hirosaki University has maintained an observatory with a total of 18 telemetering stations on the mountain since 1981. ref http www.wovo.org 0803 27.html ref Climbing Mount Iwaki Image View from Mt Iwaki in Aomori Japan.jpg thumb From the summit of Mt Iwaki left The summit, at 1625 meters ref Touring Mapple 2007 Tohoku region , Simap, 2007 in Japanese ref , can be reached only by hiking, but the length of the hike depends on the rou ... more details
Infobox scientist name Yves Br chet image image size caption birth date birth place death date death place residence citizenship nationality French ethnicity field Materials Scientist work institutions Grenoble Institute of Technology McMaster University alma mater doctoral advisor doctoral students known for author abbrev bot author abbrev zoo influences influenced prizes Silver medal of French National Centre for Scientific Research CNRS religion footnotes signature Yves Br chet is a physicist, specialist of materials science , professor at the Grenoble Institute of Technology , and a member of the French Academy of Sciences . Biography Yves Br chet graduated from cole Polytechnique 1981 , cole des hautes tudes en sciences sociales 1992 and obtained his doctoral degree and habilitation from Joseph Fourier University in 1987 and 1992, respectively. He is currently a full professor at Grenoble INP cole nationale sup rieure de physique, lectronique et mat riaux Phelma , an adjunct professor of materials science and engineering at McMaster University Canada , a senior Research Professor at the Institut Universitaire de France , and a member of the SIMaP Materials and Processes Science and Engineering Laboratory with the University of Grenoble . On November 30, 2010, he was elected to the French Academy of Sciences . ref http www.academie sciences.fr presse communique election 301110.pdf Press Release in French from the French Academy of Sciences,november 30 2010 ref Activities His activities span the fields of physical metallurgy, thermodynamics, microstructures, phase transformations, plasticity, fracture micromechanics, material selection, structural materials design, biointerfaces, structural biomimetics. He is a member of the international scientific council of ArcelorMittal and the Commissariat l nergie atomique , and a scientific advisor to Rio Tinto Alcan , EDF and ONERA . He is as member of the editorial board of J.Comp.Sim.Mat.Sc.Eng, Materials Scienc ... more details
been the SIMAP and Jaeger judgments Sindicato de M dicos de Asistencia P blica v Conselleria de Sanidad y Consumo de la Generalidad Valenciana , 2000 and Landeshauptstadt Kiel v Jaeger , 2003 . The SIMAP ... EN NOT Judgment of the Court of 3 October 2000. Sindicato de M dicos de Asistencia P blica SiMAP ... more details
apparatus. Project dates 02 06 01 09 . http www.simap project.org simap public Simap STREP Simulation modelling of the MAP kinase pathway SIMAP will develop a simulation model of the cancer ... more details
name SETI Beta stats align center SIMAP align center 2006 04 26 ref cite web url http www.setiusa.us content.php?474 simap 1 title Information on SIMAP author Cruncher Pete date 2011 09 03 accessdate ... Yes align center nts 10,598 Feb 2012 ref name SIMAP stats cite web url http boincstats.com stats ... more details
File Rush hour, Liverpool Street geograph.org.uk 479177.jpg thumb right 350px In the UK, the total working population is 32 million people, there is 8.6 unemployment , and 73.4 without Trade unions in the United Kingdom union membership . The average income is 25,498, and the average working week is 41.4 hours. United Kingdom labour law involves the legal relationship between workers, employers and trade unions. People at work in the UK benefit from a minimum charter of employment rights. ref See KW Wedderburn, The Worker and the Law 3rd edn Harmondsworth 1986 6, referring to a floor of rights , and Gisda Cyf v Barratt 2010 UKSC 41, 37 ref This includes the right to a minimum wage of 6.08 under the National Minimum Wage Act 1998 , 28 paid holidays, and no longer working hours than one consents to under the Working Time Regulations 1998 , the right to leave for child care, and the right to request flexible working patterns under the Employment Rights Act 1996 . The Equality Act 2010 ensures people are judged by the content of their character , and not regulated characteristics such as race, gender, sexuality, beliefs, disabilities or age. The Employment Rights Act 1996 adds that, unless the employee repudiates the relationship, before a dismissal every employer must give reasonable notice after one month of work, backed by a sufficiently fair reason after one year of work, and with a redundancy payment after two years. If a company is taken over the Transfer of Undertakings Protection of Employment Regulations 2006 state that employees terms cannot be worsened, including to the point of dismissal, without a good economic, technical or organisational reason. Beyond individual rights, workers have the ability to participate in decisions about how their enterprise is managed through a growing set of statutory rights and the traditional models of collective bargaining . Gradually, the number of John Lewis Partnership John Lewis style participatory institutions at work ha ... more details
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