Infobox Disease Name SertoliLeydigcelltumour Image SertoliLeydigcelltumour very high mag.jpg Width 200 Caption Micrograph of a SertoliLeydigcelltumour. The Leydigcell s have abundant eosinophilic or light pink cytoplasm . The Sertolicell s have a pale clear cytoplasm. H&E stain . DiseasesDB ... MeshID D018310 SertoliLeydigcelltumour is a group of tumours composed of variable proportions of Sertoli ... bibliographic info date April 2011 ref SertoliLeydigcelltumour is a member of the sex cord stromal ... under SertoliLeydigcelltumour in Medical Subject Headings MeSH . Classification The tumour ... is followed by surveillance. Because in many cases SertoliLeydigcelltumour does not produce elevated ... first6 Deepak title SertoliLeydigcell tumor A rare ovarian neoplasm. Case report and review of literature ... Goiter With and Without Ovarian SertoliLeydigCell Tumors journal JAMA volume 305 issue 1 pages .... Diagnosis Presence of an ovarian tumour plus hormonal disturbances suggests a SertoliLeydigcelltumour. However, hormonal disturbance is present in only 2 3 of cases. A conclusive diagnosis ... follow up of SertoliLeydigcell tumours journal Clinical Chemistry and Laboratory Medicine ... age, it occurs most often in young adults. Recent studies have shown that many cases of SertoliLeydig ... cell s and interstitial clusters of Leydigcell s. Presentation Due to excess testosterone secreted ... is on repeated physical examination and imaging. Given that many cases of SertoliLeydig ..., prognosis is poor. ref name pmid17484630 Additional images gallery Image Leydigcell tumour3.jpg High magnification micrograph of a Leydigcelltumour. H&E stain . Image Sertolicelltumour high mag.jpg High magnification micrograph of a Sertolicelltumour . H&E stain . gallery See also Androgen dependent syndromes LeydigcelltumourSertolicelltumour References reflist Gonadal tumors, paraganglioma, glomus, nevi and melanomas Genital neoplasia Male genital neoplasia DEFAULTSORT SertoliLeydig ... more details
29&issue 2&spage 143 ref A tumor that produces both Sertoli cells and Leydigcell s is known as a SertoliLeydigcelltumourSertoliLeydigcell tumor . Presentation Due to excess testosterone secreted ...Infobox Disease Name Sertolicelltumour Image Sertolicelltumour high mag.jpg Caption Micrograph of a Sertolicelltumour . H&E stain . DiseasesDB ICD10 ICD9 ICD9 183.0 , ICD9 256.1 ICDO 8631 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D012707 A Sertolicelltumour , also Sertolicell tumor US spelling , is a Sex cord gonadal stromal tumour Sex cord gonadal stromal tumor of a specific type that produces Sertolicell s. Although Sertoli cells normally occur only in the testis , this type ... Sertolicelltumour low mag.jpg thumb right 290px Low magnification micrograph of a Sertolicelltumour . H&E stain . Presence of an ovarian tumour plus hormonal disturbances suggests a Leydigcelltumour, granulosa celltumour or thecoma . However, hormonal disturbances, in Leydig tumours, is present ... Leydigcelltumour does not produce elevated tumor marker tumour marker s, ref name pmid17484630 ... Use of novel serum markers in clinical follow up of SertoliLeydigcell tumours journal Clin. Chem. Lab ... cell tumour2.jpg Micrograph of a Leydigcelltumour . Image Leydigcell tumour3.jpg Micrograph of a Leydigcelltumour. gallery See also Androgen dependent syndromes LeydigcelltumourSertoliLeydigcelltumourSertolicell nodule Notes reflist External links http www.humpath.com Sertolicell tumor ... neoplasia DEFAULTSORT SertoliCellTumour Category Gynaecological cancer Category Male genital ... DD, Scully RE title Sertolicell tumors of the testis, not otherwise specified a clinicopathologic ... with undifferentiated histology, prognosis is poor. ref name pmid17484630 In non humans Sertolicell ... celltumour journal J Small Anim Pract volume 50 issue 4 pages 198 200 year 2008 month December pmid ... Mullerian Duct Syndrome in a Miniature Schnauzer Dog with Signs of Feminization and a SertoliCell ... more details
gallery Image Leydigcell tumour2.jpg Intermediate magnification micrograph of a Leydigcelltumour. H&E stain . Image Leydigcell tumour3.jpg High magnification micrograph of a Leydigcelltumour. H&E stain . gallery See also Androgen dependent syndromes SertolicelltumourSertoliLeydigcell ...Infobox Disease Name Leydigcelltumour Image Leydigcell tumour1.jpg Caption Low magnification micrograph of a Leydigcelltumour . H&E stain . DiseasesDB ICD10 ICD9 ICD9 183.0 , ICD9 256.1 ICDO 8631 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D007984 Leydigcelltumour , also Leydigcell tumor US spelling , testicular interstitial celltumour and testicular interstitial cell tumor US spelling , is a member of the sex cord stromal tumour group ref name pmid18382911 cite journal author Sachdeva P, Arora R, Dubey C, Sukhija A, Daga M, Singh DK title SertoliLeydigcell tumor a rare ovarian ... Presence of an ovarian tumour plus hormonal disturbances suggests a Leydigcelltumour, granulosa celltumour or thecoma . However, hormonal disturbances, in Leydig tumours, is present in only ... or after surgery. See also Sex cord stromal tumour . Immunohistochemical markers of Leydigcell ... in many cases Leydigcelltumour does not produce elevated tumor marker tumour marker s, ref name ... A title Use of novel serum markers in clinical follow up of SertoliLeydigcell tumours journal ... Male genital neoplasia DEFAULTSORT LeydigCellTumour Category Gynaecological cancer Category Male ... ref of ovarian cancer ovarian and testicular cancer s. It arises from Leydigcell s. While the tumour can occur at any age, it occurs most often in young adults. A SertoliLeydigcelltumour is a combination of a Leydigcelltumour and a Sertolicelltumour from Sertolicell s. Presentation The majority of Leydigcell tumors are found in men, usually at 5 10 years of age or in middle ... Ulbright TM, Srigley JR, Hatzianastassiou DK, Young RH title Leydigcell tumors of the testis with unusual ... more details
Section of a genital cord of the testis of a human embryo 3.5 cm. long. Image Leydigcell tumour2.jpg Intermediate magnification micrograph of a Leydigcelltumour. H&E stain . Image Leydigcell tumour3.jpg High magnification micrograph of a Leydigcelltumour. H&E stain . gallery See also SertolicellSertoliLeydigcelltumour References reflist 2 External links BUHistology 16907loa http www2.ufp.pt ... ref Pathology Image Leydigcell tumour3.jpg thumb right 100px Micrograph of a Leydigcelltumour . H&E stain . Leydig cells may grow uncontrollably and form a Leydigcelltumour . These tumours ...Infobox Anatomy Name Leydigcell Latin GraySubject 258 GrayPage 1243 Image Testicle histology boar 2.jpg ... doi abs 10.3109 01485019208987723 ref Ultrastructure The mammalian Leydigcell is a polyhedral epithelioid ... An in depth look at Leydigcell tumor of the testis journal Arch Pathol Lab Med volume 131 issue ... Reinke1 cite web author Ramnani, Dharam M title LeydigCell Tumor Reinke s Crystalloids url http ... is another example of a disease affecting the Leydigcell the patient s testosterone ... 700 Leefig1.jpg Diagram at umassmed.edu Male reproductive system Human cell types DEFAULTSORT Leydig ... of the seminiferous tubules, 2 spermatid s, 3 spermatocyte s, 4 spermatogonium spermatogonia , 5 Sertolicell , 6 myofibroblast s, 7 Leydig cells, 8 capillary capillaries Image2 Leydig cells.JPG Caption2 Cross section of seminiferous tubules. Arrows indicate location of Leydig cells. System MeshName Leydig cells MeshNumber DorlandsPre c 18 DorlandsSuf 12224005 Leydig cells , also known as interstitial cells of Leydig , are found adjacent to the seminiferous tubules in the testes testicle . They produce testosterone in the presence of luteinizing hormone LH . Leydig cells are polyhedral in shape, display a large prominent cell nucleus nucleus , an eosinophilic cytoplasm and numerous lipid filled vesicles. Nomenclature Leydig cells are named after the German anatomist Franz Leydig , who discovered ... more details
for Veterinary Health Sciences OSU CVHS Home Bot generated title ref Pathology SertoliLeydigcell ...Infobox Anatomy Name Sertolicell Latin GraySubject 258 GrayPage 1243 Image Germinal epithelium testicle.svg ... 1st order br 4 spermatocyte 2nd order br 5 spermatid br 6 mature spermatid br 7 Sertolicell ... spermatids br 3 spermatocytes br 4 Spermatogonium spermatogonia br 5 Sertolicell br 6 Myofibroblasts br 7 Leydigcell s br 8 capillaries System MeshName Sertoli Cells MeshNumber A05.360.444.849.789 A Sertolicell a kind of sustentacular cell is a nurse cell biology cell of the testicle testes that is part ... is to nourish the developing sperm cells through the stages of spermatogenesis , the Sertolicell has also been called the mother or nurse cell. Sertoli cells also act as phagocytes, consuming the residual .... Production of Sertoli cells Once fully differentiated, the Sertolicell is unable ... in 1865. The cell was discovered by Sertoli with a Belthle microscope purchased in 1862, which ... scientists who used Enrico s family name, Sertoli, to label these cell in publications, starting in 1888. As of 2006, two textbooks that are devoted specifically to the Sertolicell have been published ... See also Sertolicell only syndrome Sertolicell nodule References Reflist External links BUHistology 17805loa BUHistology 17806loa Male reproductive system Human cell types DEFAULTSORT Sertoli ... Sertolicell sl Sertolijeva celica fi Sertolin solu sv Sertolicell zh ... tubules occurs by conformational changes in the lateral margins of the Sertoli cells. Secretory Sertoli cells secrete the following substances anti M llerian hormone AMH secreted during ... spermiogenesis estradiol aromatase from Sertoli cells convert testosterone to 17 beta estradiol to direct spermatogenesis glial cell line derived neurotrophic factor GDNF has been demonstrated to function in promoting undifferentiating spermatogonia, which ensures stem cell self renewal during ... more details
Infobox Disease Name Sertolicell nodule Image Sertolicell nodule high mag.jpg Caption Micrograph of a Sertolicell nodule . H&E stain . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID A Sertolicell nodule , also Pick s adenoma , testicular tubular adenoma and tubular adenoma of the testis , is a benign hyperplasia proliferation of Sertolicell s that arises in association with cryptorchidism undescended testis . They are not composed of a clonal cell population, i.e. w neoplasm neoplastic thus, technically, they should not be called an w adenoma adenoma . ref name tadrous cite book title Diagnostic criteria handbook in histopathology a surgical pathology vade mecum last Tadrous first Paul J. authorlink coauthors year 2007 publisher John Wiley & Sons Canada Ltd location isbn 978 0 470 51903 5 page 227 pages url accessdate ref Pathology Sertolicell nodules are unencapsulated nodules that consist of ref name tadrous ref cite journal author Ricco R, Bufo P title Histologic study of 3 cases of so called tubular adenoma of the testis language Italian journal Boll. Soc. Ital. Biol. Sper. volume 56 issue 20 pages 2110 5 year 1980 month October pmid 6109541 doi url ref cells arranged in well formed tubules that vaguely resemble immature Sertoli cells , with bland hyperchromatic oval round nuclei that are stratified, and may contain eosinophilic hyaline blob in lumen centre . Additional images gallery Image Sertolicell nodule intermed mag.jpg Micrograph of a Sertolicell nodule . H&E stain . Image Sertolicell nodule low mag.jpg Micrograph of a Sertolicell nodule . H&E stain . gallery See also SertolicellSertolicelltumour References reflist ... eMedicine . http jcp.bmj.com cgi content abstract 57 8 802 Sertolicell nodules in the undescended ... http jcp.bmjjournals.com cgi content abstract 59 11 1223 Giant Sertolicell nodule of the testis distinction from other Sertolicell lesions bmj.com. Category Testicle disorders ... more details
Infobox Disease Name Sertolicell only syndrome Image File tbowing.jpg Caption DiseasesDB 31907 ICD10 ICD9 ICDO OMIM 305700 OMIM mult OMIM2 400042 MedlinePlus eMedicineSubj med eMedicineTopic 2104 eMedicine mult MeshID D054331 Sertolicell only syndrome a.k.a. Del Castillo syndrome and germ cell aplasia ref EMedicine Med 2104 Sertolicell only syndrome ref is a disorder characterized by male sterility without sexual abnormality. It is the result of absent seminiferous tubule s in the testes of germinal epithelium, while Sertolicell s are present. ref http cancerweb.ncl.ac.uk cgi bin omd?Sertolicell only syndrome Online Medical Dictionary . ref Features The Sertolicell only syndrome patients normally have normal secondary male features and have normal or small sized testes. Diagnosis Testicular biopsy would confirm the absence of spermatozoa . Pathophysiology Sertolicell only syndrome is likely multifactorial, and characterized by severely reduced or absent spermatogenesis despite the presence of both Sertoli and Leydig cells. A substantial subset of men with this uncommon syndrome have microdeletions in the Yq11 region of the Y chromosome, an area known as the Azoospermia factor AZF azoospermia factor region. Generally speaking, testosterone and LH levels are normal, but due to lack of inhibin, FSH levels are increased. Treatment Sertolicell only syndrome is like other non obstructive azoospermia NOA cases are managed by sperm retrieval through testicular sperm extraction m TESE , micro surgical testicular sperm extraction mTESE , or testicular biopsy. ref cite journal author Talas H, Yaman O, Aydos K title Outcome of repeated micro surgical testicular sperm extraction in patients with non obstructive azoospermia journal Asian J Androl. volume 9 issue 5 pages 668 73 ... Congenital disorders of male genital organs pl Zesp samych kom rek Sertolego tr Sertolicell ... this could be used in Intracytoplasmic Sperm injection ICSI In 1979, Levin described germinal cell ... more details
Infobox disease Name Granulosa celltumour ICD10 ICD10 C 56 c 51 ICD9 ICD9 183 ICDO 8620 Image Juvenile granulosa celltumour very high mag.jpg Caption Micrograph of a juvenile granulosa celltumour with hyaline globules. H&E stain . OMIM MedlinePlus eMedicineSubj med eMedicineTopic 928 DiseasesDB MeshID D006106 Granulosa cell tumours or granulosa theca cell tumours are tumor tumour s that arise from granulosa cell s. These tumours are part of the sex cord gonadal stromal tumour or non epithelial group of tumours. Although granulosa cells normally occur only in the ovary , granulosa cell tumours occur in both ovaries and testicles see Ovarian cancer and Testicular cancer . These tumours should be considered malignant and treated in the same way as other malignant tumours of ovary. The staging ... is 50 55 years, but they may occur at any age. Juvenile granulosa celltumour is a similar but distinct rare tumour. It too occurs in both the ovary and testis. In the testis it is extremely rare, and has ... 02.htm indiandoctors.com http www.humpath.com spip.php?article7794 Juvenile granulosa cell tumor HP 7794 at humpath.com http gctrf.org Granulosa CellTumour Research Foundation Gonadal tumors, paraganglioma, glomus, nevi and melanomas Genital neoplasia DEFAULTSORT Granulosa CellTumour Category Gynaecological ... L, Sultania P, Jha K, Florens A, Joseph T title Juvenile granulosa cell tumor of testis case report ... issn ref Although this tumour usually occurs in children hence its name , it has been reported ... cell tumor of adult testis a case report journal Urology volume 72 issue 1 pages 230.e11 3 year 2008 ... Gene defect Using next generation DNA sequencing , it was discovered that 97 of granulosa cell tumours ... that this mutation may be the cause of granulosa cell tumours. Tumor marker Inhibin, a hormone, has been used as tumor marker for granulosa cell tumor. Granulosa cell clusters in other species In the ovaries ... granulosa cell tumours in humans. ref name MLWalker1 cite journal author Walker ML, Anderson DC ... more details
accessdate ref Examples Tumours that belong to this group are Desmoplastic small round cell tumor Desmoplastic small round celltumour Ewing s Sarcoma Primitive neuroectodermal tumor PNET ref name ... a small blue round celltumour. Endometrial stromal condensation may mimic a small blue round celltumour. References reflist 2 Smallblueroundcelltumors Category Small blue round cell tumor pl Nowotwory ... of a molecular taxonomy of small blue round cell tumors using cDNA microarrays Nature Genetics ... of a molecular taxonomy of small blue round cell tumors using cDNA microarrays Nature Genetics author ... blue cell tumors using multiplex polymerase chain reaction journal J Mol Diagn volume 9 issue 1 ... Medulloblastoma Rhabdomyosarcoma ref name pmid17251339 Wilms tumor Wilms tumour ref name pmid18613926 Retinoblastoma Citation needed date June 2009 Small cell lymphoma ref name pmid17251339 Hepatoblastoma ... more details
to morphology biology morphology . ref name FranzWNI In the Lehrbuch , Leydig reviewed the crucial developments in the history of histology , including the discovery and definition of the Cell biology cell by Jan Evangelista Purkyne 1797 1869 , Gabriel Valentin Gabriel Gustav Valentin 1810 1883 , and by Theodor Schwann Theodor Ambrose Hubert Schwann 1810 1882 , who described the cell as a vesicle containing a Cell nucleus nucleus in 1839. ref name FranzWNI Leydig paid further tribute to other ... among Leydig s discoveries is the interstitial cellLeydig cells , a body enclosed in a smooth endoplasmic ... the surface of the epithelium Leydig believed that the cell function was to lubricate the skin, and the cell ...File Franz Leydig.jpg thumb Franz von Leydig May 21, 1821 April 13, 1908 , also Franz Leydig , was a Germans German zoologist and comparative anatomist . ref name FranzWNI Franz von Leydig biography , Ole Daniel Enerson, 2006, WhoNamedIt.com http www.whonamedit.com doctor.cfm 675.html WNI 675 Leydig . ref Life Franz Leydig was born on May 21, 1821, in Rothenburg ob der Tauber on the Tauber river . ref name FranzDE Franz von Leydig Wikipedia German language German , German Wikipedia, 2006 10 29, de.wikipedia.org webpage de Franz von Leydig GermanWP Franz von Leydig . ref He was the only boy of three children born to Melchior Leydig, a Catholic and a minor public official, and Margareta, a Protestant . ref name FranzWNI Leydig shared both his father s Catholic religion and hobbies his father was a keen gardener and beekeeper . Leydig himself recalled later that those childhood interests began ... microscope , which he used in the majority of his free time. ref name FranzWNI Leydig studied philosophy ... of 1850 1851, Leydig made a journey to Sardinia , where he became aware of the rich marine life ... In 1857 Leydig became full professor of Zoology and Comparative anatomy at the University of T bingen ... cellular doctrine for pathology . ref name FranzWNI Leydig s book was published at the time ... more details
Image Enrico Sertoli.png thumb Enrico Sertoli Enrico Sertoli June 6, 1842 January 28, 1910 was an Italian physiologist and histologist who was a native of Sondrio . He studied medicine at the University of Pavia , where one of his instructors was physiologist Eusebio Oehl 1827 1903 . He continued his studies of physiology in Vienna under Ernst Wilhelm von Br cke 1819 1892 , and in T bingen with Felix Hoppe Seyler 1825 1895 . From 1870 until 1907, Sertoli was a professor of anatomy and physiology at the Royal School of Veterinary Medicine in Milan , and after 1907 a professor of physiology. In Milan he founded the Laboratory of Experimental Physiology. Sertoli is remembered for his 1865 discovery of the eponymous Sertolicell . These cells line the tubuli seminiferi contorti of the testis , and provide nourishment and support for developing sperm . Writings Dell esistenza di particolari cellule ramificate nei canalicoli seminiferi del testicolo umano . Morgagni, 1865 , 7 31 40. Osservazioni sulla struttura dei canalicoli seiminiferi del testicolo . Gazzetta medica lombarda, Milano, 1871 , 4 d.s. 6 413 415. Sulla struttura dei canalicoli seiminiferi del testicolo studiata in rapporto allo sviluppo dei nemaspermi . Gazzetta medica lombarda, Milano, 1875 , 2 d.s. 401 403. References http www.whonamedit.com doctor.cfm 556.html Enrico Sertoli Who Named It Persondata Metadata see Wikipedia Persondata . NAME Sertoli, Enrico ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH June 6, 1842 PLACE OF BIRTH DATE OF DEATH January 28, 1910 PLACE OF DEATH DEFAULTSORT Sertoli, Enrico Category Italian physicians Category Italian physiologists Category University of Pavia alumni Category 1842 births Category 1910 deaths Category People from Sondrio italy med bio stub de Enrico Sertoli fr Enrico Sertoli it Enrico Sertoli ... more details
Leydig s Organ named after the German histologist Franz Leydig who first described it in 1857 is a unique structure that is only found in Elasmobranchii elasmobranchs shark s and Batoidea rays , although some elasmobranchs lack this organ. Along with the spleen and special tissue around the gonad s, this structure produces red blood cell s and it is nestled along the top and bottom of the esophagus . ref cite journal last Honma first Yoshiharu authorlink coauthors Okabe, Kazuyuki Chiba, Akira year 1984 month title Comparative histology of the Leydig and epigonal organs in some elasmobranchs trans title journal Japanese Journal of Ichthyology volume 31 issue 1 pages 47 54 id url http www.wdc jp.biz pdf store isj publication pdf 31 311 31107.pdf format PDF accessdate 2009 08 31 quote ref Notes reflist References cite web url http www.elasmo research.org education topics p blood cells.htm title Without Bones, How Do Sharks Make Red Blood Cells? publisher ReefQuest Centre for Shark Research accessdate January 2010 anatomy stub shark stub diversity of fish Category Fish anatomy ... more details
male Mixed rowspan 3 Cell tissue type Sex cord Granulosa celltumourSertolicell tumor Sertolicelltumour Gynandroblastoma stromal cell Gonadal stroma Thecoma , Fibroma Leydigcell tumor Leydigcelltumour Gynandroblastoma Mixed SertoliLeydigcelltumour Gynandroblastoma Although each of the cell .... Leydigcell tumor Leydigcelltumour . This tumour produces Leydigcell s, which normally are found in the testicle and tend to secrete androgens. SertoliLeydigcelltumour . This tumour produces both Sertoli and Leydig cells. Although both cell types normally occur in the testicle, this tumour ... tumour and 10 with SertoliLeydigcelltumour , all diagnosed between 1975 and 2003, reported that survival ... treatment is the mainstay for non metastatic disease. Sertolicell tumor Sertolicelltumour . This tumour produces Sertolicell s, which normally are found in the testicle . This tumour occurs in both ... Leydigcell tumour1.jpg Low magnification micrograph of a Leydigcelltumour . H&E stain . Image Leydigcell tumour2.jpg Intermediate magnification micrograph of a Leydigcelltumour . H&E stain . Image Leydigcell tumour3.jpg High magnification micrograph of a Leydigcelltumour . H&E stain . Image Sertolicelltumour low mag.jpg Low magnification micrograph of a Sertolicelltumour . H&E stain . Image Sertolicelltumour high mag.jpg High magnification micrograph of a Sertolicelltumour . H&E ...Cleanup date March 2009 Infobox disease Name Sex cord gonadal stromal tumour Image Granulosa cell tumour2.jpg Caption Micrograph of a granulosa celltumour , a type of sex cord stromal tumour . H&E stain .... This group of tumours is significantly less common than testicular germ cell tumor germ celltumour ... celltumour . This tumour produces granulosa cells , which normally are found in the ovary. It is malignant ... menopausal vaginal bleeding. Uncommonly, a similar but possibly distinct tumour, granulosa celltumour juvenile granulosa celltumour , presents in pre pubertal girls with precocious puberty. In both ... more details
Infobox Disease Name Serous tumour Image Serous carcinoma cytology.jpg Caption Micrograph of serous carcinoma , a type of serous tumour . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic eMedicine mult MeshID Serous tumours are part of the surface epithelial stromal tumour group of Ovarian cancer ovarian neoplasm s. They are common neoplasm s with a strong tendency to bilaterality, and they account for 50 of all ovarian tumours. Sixty percent are benign , 10 are borderline and 30 are malignant . Explanation Benign serous tumours are unilocular have one lobe however if very large may be multilocular, contain clear fluid and have a smooth lining composed of columnar epithelial cell s with cilia . Surgery is curative. In borderline lesions, the cyst or surface is lined by papillary structures, which are often very complex. Surgery is usually curative. Microscope Microscopically , stromal papillae are covered by atypical epithelial cell s, but stromal invasion is absent, nuclear stratification is present. Malignant serous tumours are solid, may be cystic and often show haemorrhage and necrosis . They are lined by a complex papillary pattern with presence of nuclear anaplasia. Serous carcinomas often have bulky peritoneum peritoneal and omentum omental metastases , and spread to the lymph node s is frequent. Unsurprisingly, 5 year survival decreases as the stage increases. There is a 25 survival rate with a stage III serous carcinoma. Staging Stage I Tumour growth limited to ovaries. Stage II Growth involving one or both ovaries with pelvic extension. Stage III Tumour involving one or both ovaries with implants outside pelvis. Stage IV Tumour involving one or both ovaries with presence of distant metastasis. See also Ovarian cancer Serous carcinoma retained ancestor category for benign cases DEFAULTSORT Serous Tumour retained ancestor category for benign cases Category Gynaecological cancer Oncology stub ... more details
Infobox Disease Name Kidney tumour Image Renal oncocytoma2.jpg Caption Micrograph of a renal oncocytoma , a type of benign kidney tumour . H&E stain . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Kidney tumours or kidney tumors , also known as renal tumours , are tumour s, or growths, on or in the kidney . These growths can be benign or malignant cancerous . They may be discovered on medical imaging incidentally i.e. an incidentaloma , or may be present in patients as an abdominal mass, hematuria , abdominal pain , or manifest first in a paraneoplastic syndrome that seems unrelated to the kidney. ref cite journal author Gill IS, Aron M, Gervais DA, Jewett MA title Small renal mass journal N. Engl. J. Med. volume 362 issue 7 pages 624 34 year 2010 month February pmid 20164486 doi 10.1056 NEJMcp0910041 url http content.nejm.org cgi pmidlookup?view short&pmid 20164486&promo ONFLNS19 ref Classification There are many forms of kidney tumours Malignant cancerous The most frequent, malignant, primary kidney cancer is renal cell carcinoma RCC which has several subtypes Clear cell RCC. Papillary RCC Chromophobe RCC Collecting duct RCC Metastatic tumour, e.g. ovarian carcinoma. Benign Renal oncocytoma Cystic nephroma Angiomyolipoma Metanephric adenoma Renal medullary fibroma References references External links Urologic neoplasia Category Kidney cancer oncology stub ... more details
Infobox Disease Name Brenner tumour Image Brenner Tumor of Ovary.jpg Caption A Brenner tumour of ovary gross examination gross image . DiseasesDB 33431 ICD10 ICD9 ICD9 220 ICDO 9000 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D001948 Brenner tumours are uncommon tumours that are part of the surface epithelial stromal tumour group of Ovarian cancer ovarian neoplasm s. The majority of these tumours are benign . However, they can be malignant . ref name pmid16758686 cite journal author Marwah N, Mathur SK, Marwah S, Singh S, Karwasra RK, Arora B title Malignant Brenner tumour a case report journal Indian J Pathol Microbiol volume 48 issue 2 pages 251 2 year 2005 pmid 16758686 doi ref They are most frequently found as incidental findings ref name pmid16998096 cite journal author Green GE, Mortele KJ, Glickman JN, Benson CB title Brenner tumors of the ovary sonographic and computed tomographic imaging features journal J Ultrasound Med volume 25 issue 10 pages 1245 51 quiz 1252 4 year 2006 pmid 16998096 doi url http www.jultrasoundmed.org cgi pmidlookup?view long&pmid 16998096 ref on pelvic examination or at laparotomy . Brenner tumours very rarely can occur in other locations, including ... Image Brenner tumour intermed mag.jpg thumb right Micrograph of a Brenner tumour . H&E stain . Image Brenner tumour high mag cropped.jpg thumb right High magnification micrograph of a Brenner tumour ... fibrous stroma. Similar conditions Transitional cell carcinoma is an even rarer entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, without the characteristic stromal epithelial pattern of a Brenner tumour ... 586 ref Additional images gallery Image Walthard cell rest very high mag.jpg Micrograph of a Walthard cell nest , the entity Brenner tumours are thought to arise from. H&E stain . gallery References ... Brenner Tumour Category Gynaecological cancer oncology stub de Brenner Tumor pl Guz Brennera ... more details
Refimprove date February 2011 The anterior pituitary secretes a number of hormones including Growth hormone GH Prolactin PRL Thyroid stimulating hormone TSH Adrenocorticotropic hormone ACTH Melanocyte stimulating hormone MSH not produced in humans ref Brook, Charles. Essential Endocrinology . 4th Ed. Blackwell Publishing, 2001, p. 38. ref Follicle stimulating hormone FSH Luteinizing hormone LH Although theoretically a tumour could secrete any of these hormones, the common tumours secrete growth hormone see acromegaly , prolactin see prolactinoma and hyperprolactinaemia , mixed secretions or no secretion at all. Once tumours were categorised by their light microscopic appearance but now tumours are more reliably categorised by immunoperoxidase studies. Blood tests for the hormones are important diagnostic tools. CT scans, MRI and other imaging techniques are important for determining size and seriousness of tumours , growth over time and treatment options. Most tumours are benign but are quite serious because of their position close to important brain structures. Treatment includes Bromocriptine Surgical removal Ablation by radiotherapy References Reflist DEFAULTSORT Pituitary Tumour Category Endocrine neoplasia ... more details
Multiple issues refimprove May 2009 orphan December 2010 Cock s peculiar tumour is a sebaceous cyst linked growth. ref cite book last Ramachandran first Manoj coauthors Adam Poole title Clinical cases and OSCEs in surgery publisher Elsevier Health Sciences year 2003 page 9 isbn 9780443070440 url http books.google.com books?id 7WAEfWcQweAC&pg PA3&lpg PA3&dq 22Cock 27s peculiar tumour 22 wikipedia&source bl&ots iWWGybvKtl&sig gd6V8yOWBWscfF90AWwsbaykDKI&hl en&ei PN0ZSqWOJ5 OtgPe9bDeCA&sa X&oi book result&ct result&resnum 3 accessdate May 24, 2009 ref One form of sebaceous cyst is the trichilemmal cyst these are thought to arise from the hair follicle epithelium and are most commonly found on the scalp . Usually they are multiple but occasionally there can be a proliferating trichilemmal cyst which grows to a large size and ulcerates. These can resemble a squamous cell carcinoma both clinically and histologically and these ulcerating solitary cysts are called Cock s peculiar tumour. Chronic inflammation causes the cyst to take the form of a granuloma . This granuloma mimics a squamous celltumour. Hence it is a misnomer. It is not a tumour but looks like a tumour. The most common sites are the ones where one can find hairs. these are, scalp and scrotum . References references DEFAULTSORT Cock s Peculiar Tumour Category Integumentary neoplasia ... more details
wiktionary cellCell s may refer to TOCright Science and technology Cell biology , the functional basic unit of life Cell EDA , a term used in an electronic circuit design schematics Cell geometry , a three dimensional element, part of a higher dimensional object Cell journal Cell journal , a scientific journal Cell microprocessor , a microprocessor architecture developed by Sony, Toshiba, and IBM Cell, the basic unit of Flash memory Principles of operation Flash memory Cell or mobile phone , a phone connected to a cellular network Cell, area of radio coverage in a cellular network Cell, a basic unit of a cellular automaton Electrochemical cell , a device used to convert chemical energy to electrical energy Galvanic cell or Voltaic cell, a particular kind of electrochemical cell Music Cell music , a small rhythmic and melodic design that can be isolated, or can make up one part of a thematic context. Fiction Cell comics , a Marvel comic book character Cell, a List of Dragon Ball characters Cell character in Dragon Ball media Cell novel Cell novel , a 2006 horror novel by Stephen King Cell, the name of two different Web television series, from 2008 and 2010 respectively. Society Prison cell , a room used to hold people in prisons Cell, a unit of a clandestine cell system , a penetration resistant form of a secret or outlawed organization Cell, a group of people in a cell group , a form of Christian church organization. Religion Cell, a room or hut in which a monk or nun lives. See also The Cell disambiguation Cellular disambiguation CEL disambiguation disambiguation cs Cell cy Cell da Celle de Cell es C lula desambiguaci n eo elo apartigilo fr Cell gl C lula hom nimos ko it Cell he nl Cel ja no Celle andre betydninger pl Cell pt Cell ro Celul ru simple Cell disambiguation sk Bunka rozli ovacia str nka sr sh elija su S l fi Solu t smennyssivu sv Cell olika betydelser th ... more details
Infobox Disease Name PAGENAME Image Inflammatory myofibroblastic tumour high mag.jpg Caption Micrograph of an inflammatory myofibroblastic tumour of the kidney. Kidney biopsy . H&E stain . DiseasesDB ICD10 ICD9 ICDO ICDO 8825 1 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Inflammatory myofibroblastic tumour , also known as inflammatory pseudotumour , plasma cell granuloma , ref name pmid21772725 Cite journal last1 Manohar first1 B. last2 Bhuvaneshwari first2 S. title Plasma cell granuloma of gingiva. journal J Indian Soc Periodontol volume 15 issue 1 pages 64 6 month Jan year 2011 doi 10.4103 0972 124X.82275 PMID 21772725 ref and inflammatory fibrosarcoma , is a soft tissue lesion that may be confused with a sarcoma . It is abbreviated IMT . Symptoms The symptoms depend on the specific location of the tumour, which can be anywhere in the body. ref name pmid21435987 Cite journal last1 Singhal first1 M. last2 Ramanathan first2 S. last3 Das first3 A. last4 Singh first4 G. last5 Bagga first5 R. last6 Khandelwal first6 N. title Omental inflammatory myofibroblastic tumour mimicking peritoneal carcinomatosis. journal Cancer Imaging volume 11 issue pages 19 22 month year 2011 doi 10.1102 1470 7330.2011.0005 PMID 21435987 ref Diagnosis Inflammatory myofibroblastic tumours are diagnosed based on their appearance under the microscope , by pathologist s. ref name pmid21902993 Cite journal last1 Soga first1 H. last2 Yao first2 A. last3 Matsushita first3 K. last4 Shimogaki first4 H. last5 Kawabata first5 G. title Inflammatory pseudotumor of the retroperitoneum removed via a retroperitoneoscopic approach. journal JSLS volume 15 issue 2 pages 272 4 month year doi 10.4293 108680811X13071180406871 PMID 21902993 ref Medical imaging findings are non specific. Pathology Inflammatory ... and eosinophils , and bland spindle cell s without nuclear atypia . These tumours may have necrosis ... includes calcifying fibrous pseudotumour, inflammatory fibroid tumour and nodular fasciitis ... more details
Infobox Disease Name Solid pseudopapillary tumour Image Solid pseudopapillary tumour high mag.jpg Caption Micrograph of a solid pseudopapillary tumour. H&E stain . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID A solid pseudo papillary tumour also known as solid pseudopapillary neoplasm or, more formally, solid pseudopapillary tumour neoplasm of the pancreas is a benign neoplasm of the pancreas that typically afflicts young women. Gross morphology Solid pseudopapillary tumours are typically round, well demarcated, measuring 2 17  cm in diameter average 8  cm , with solid and cystic areas with hemorrhage on cut sections. ref cite book author Fletcher CDM title Diagnostic Histopathology of Tumors publisher Elsevier year 2007 page 478 edition 3rd volume I ref Histomorphology Solid pseudopapillary tumours consist of solid sheets of cells that are focally dyscohesive. The cells in the lesion usually have uniform nucleus cell nuclei with occasional nuclear grooves, eosinophilic or clear cytoplasm and Periodic acid Schiff stain PAS positive eosinophilic intracytoplasmic globules. ref cite journal author Serra S, Chetty R title Revision 2 an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas journal J. Clin. Pathol. volume 61 issue 11 pages 1153 9 year 2008 month November pmid 18708424 doi 10.1136 jcp.2008.057828 url http jcp.bmj.com content 61 11 1153 ref Necrosis is usually present and, as cell death preferentially occurs distant from blood vessels, lead to the formation of pseudopapillae. Immunohistochemistry Solid pseudopapillary tumours show positive nuclear staining for beta catenin, as well as positive immunostaining for CD10 , CD56 , vimentin , alpha 1 antitrypsin , and neuron specific enolase they are negative for chromogranin and pancreatic enzymes. ref cite journal author St mmer P, Kraus J, Stolte M, Giedl J title Solid and cystic pancreatic tumors. Clinical, histochemical, and electron ... more details
Unreferenced stub auto yes date December 2009 Infobox Anatomy Name PAGENAME Latin endocrinocytus S GraySubject GrayPage Image Caption Image2 Caption2 Precursor System Artery Vein Nerve Lymph MeshName MeshNumber Code Terminologia Histologica TH H3.04.02.0.00037 S cells are cells which release secretin , found in the jejunum and duodenum . They are stimulated by a drop in pH to 4 or below in the small intestine s lumen. The released secretin will increase the secretion of HCO sub 3 sub sup sup into the lumen, via the pancreas . S cells are also one of the main producers of cyclosamatin . Gastrointestinal physiology Human cell types derived primarily from endoderm DEFAULTSORT S Cell Category Human cells Category Digestive system Cell biology stub ru S sv S cell ... more details
Infobox Anatomy Name T cell Latin lymphocytus T GraySubject GrayPage Image Red White Blood cells.jpg Caption Scanning electron micrograph of T lymphocyte right , a platelet center and a red blood cell ... 2 00 04.1.02007 T cells or T lymphocytes belong to a group of white blood cell s known as lymphocyte s, and play a central role in cell mediated immunity . They can be distinguished from other lymphocytes, such as B cell s and natural killer cell s NK cells , by the presence of a T cell receptor TCR on the cell surface. They are called T cells because they mature in the thymus , and thus .... Types Helper T helper cell T sub H sub cells assist other white blood cells in immunologic processes, including maturation of B cell s into plasma cell s and memory B cell s, and activation of cytotoxic ... cell s APCs . Once activated, they divide rapidly and secrete small proteins called cytokine s that regulate ... subtypes, including T helper cell T sub H sub 1 , Th2 T sub H sub 2 , Th3 T sub H sub 3 , Th17 T sub ... and T cell polarization in autoimmune inflammation publisher Jci.org date 2007 05 01 accessdate 2012 04 09 ref Cytotoxic Cytotoxic T cell s T sub C sub cells, or CTLs destroy virally infected ... on the surface of nearly every cell of the body. Through IL 10, adenosine and other molecules secreted ... cgi content full 114 9 1198 title An integrated view of suppressor T cell subsets in immunoregulation publisher Jci.org date 2004 11 01 accessdate 2012 04 09 ref Memory Memory T cell s are a subset ... may be either CD4 sup sup or CD8 sup sup . Memory T cells typically express the cell surface protein ... 1988 publisher Ncbi.nlm.nih.gov date 2012 03 13 accessdate 2012 04 09 ref Regulatory Regulatory T cell ... of immunological tolerance . Their major role is to shut down T cell mediated immunity toward the end ... . Mutations of the FOXP3 gene can prevent regulatory T cell development, causing the fatal autoimmune ... may originate during a normal immune response. Natural killer Natural killer T cell s NKT cells not to be confused ... more details
About Infobox film name The Cell image Thecellposter.jpg caption Original film poster director Tarsem ... million gross 104,155,843 The Cell is a 2000 science fiction psychological thriller film directed by Tarsem Singh , and starring Jennifer Lopez , Vince Vaughn and Vincent D Onofrio . Plot The cell is the structural ... page xc ref Stargher s victim is imprisoned in a prison cellcell in the form of a glass enclosure ... to take care of an advanced water pump, which he used to fill the cell with water . Novak discovers ... Dean Norris as Cole Artistic influences Some of the scenes in The Cell are inspired by works ... Cite web url http www.imdb.com title tt0209958 trivia title IMDB The Cell ref The scene where the Special ... Pavilion in Barcelona, Spain. Reception Critical reaction to The Cell has been mixed, with a score of 45 on Rotten Tomatoes based on 143 reviews. ref http www.rottentomatoes.com m the cell 2000 The Cell Movie Reviews, Pictures Rotten Tomatoes ref Roger Ebert gave the film four stars out ... apps pbcs.dll article?AID 20000818 REVIEWS 8180303 1023 The Cell rogerebert.com Reviews ref ... ref James Berardinelli gave the film three stars out of four, writing The Cell becomes the first ... an ordinary child into an inhuman monster. There are no easy answers, and The Cell doesn t pretend ... who are up to the challenge, it s worth spending time in The Cell . ref http www.reelviews.net php review template.php?identifier 975 Cell, The A movie review by James Berardinelli ref Conversely ... &mdash in flames. The Cell serves up some of the most gruesomely misogyny misogynistic imagery ... movies capsules 19239 CELL.html The Cell Capsule by Jonathan Rosenbaum From the Chicago ... The Cell 2 A sequel was released Direct to video direct to DVD on June 16, 2009. The story centers ... External links IMDb title 0209958 Amg title 195764 mojo title cell Rotten tomatoes 13516 The Cell Tarsem Singh DEFAULTSORT Cell Category 2000 films Category 2000s science fiction films Category 2000s ... more details
Infobox Disease Name Keratocystic odontogenic tumour Image Keratocystic odontogenic tumour intermed mag.jpg Caption Micrograph of a keratocystic odontogenic tumour . H&E stain . DiseasesDB ICD10 ICD10 K 09 0 k 00 ICD9 ICD9 526.0 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID A keratocystic odontogenic tumour also keratocystic odontogenic tumor , abbreviated KCOT , ref name madras cite journal author Madras J, Lapointe H title Keratocystic odontogenic tumour reclassification of the odontogenic keratocyst from cyst to tumour journal J Can Dent Assoc volume 74 issue 2 pages 165 165h year 2008 month March pmid 18353202 doi url http www.cda adc.ca jcda vol 74 issue 2 165.html ref is a rare and benign but locally aggressive developmental cyst ic neoplasm . It most often affects the posterior human mandible mandible . It was previously called odontogenic keratocyst and abbreviated OKC . ref name madras ref cite journal author Mateus GC, Lanza GH, de Moura PH, Marigo Hde A, Horta MC title Cell proliferation and apoptosis in keratocystic odontogenic tumors journal Med Oral Patol Oral Cir Bucal volume 13 issue 11 pages E697 702 year 2008 month November pmid 18978709 doi url http www.medicinaoral.com medoralfree01 v13i11 medoralv13i11p697.pdf ref Diagnosis The definitive diagnosis is by histologic analysis, i.e. wikt excision excision and examination under the microscope. Under the microscope , KCOTs vaguely resemble keratinized squamous epithelium ref Thompson LDR. Head and neck pathology Foundations in diagnostic pathology . Goldblum JR, Ed.. Churchill Livingstone. 2006. ISBN 0 443 06960 3. ref however, they lack rete ridges and often have an artifactual separation from ... with impacted teeth. Multiple odontogenic keratocysts are a feature of nevoid basal cell carcinoma syndrome ... Orthokeratocyst Malignant transformation Malignant transformation to squamous cell carcinoma ... Odontogenic Tumour Category Jaw disorders Category Odontogenic tumors ja pt Ceratocisto ... more details