Orphan date February 2009 PBB geneid 23589 Calcium regulated heat stable protein 1 is a protein that in humans is encoded by the CARHSP1 gene . ref name pmid9712905 cite journal author Groblewski GE, Yoshida M, Bragado MJ, Ernst SA, Leykam J, Williams JA title Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells journal J Biol Chem volume 273 issue 35 pages 22738 44 year 1998 month Sep pmid 9712905 pmc doi 10.1074 jbc.273.35.22738 ref ref name entrez cite web title Entrez Gene CARHSP1 calcium regulated heat stable protein 1, 24kDa url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 23589 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Wishart MJ, Dixon JE title The archetype STYX dead phosphatase complexes with a spermatid mRNA binding protein and is essential for normal sperm production. journal Proc. Natl. Acad. Sci. U.S.A. volume 99 issue 4 pages 2112 7 year 2002 pmid 11842224 doi 10.1073 pnas.251686198 pmc 122327 cite journal author Wistow G, Bernstein SL, Wyatt MK, et al. title Expressed sequence tag analysis of human RPE choroid for the NEIBank Project over 6000 non redundant transcripts, novel genes and splice variants. journal Mol. Vis. volume 8 issue pages 205 20 year 2002 pmid 12107410 doi cite journal author Strausberg RL, Feingold EA, Grouse LH, et al. title Generation and initial analysis of more than 15,000 full length human and mouse cDNA sequences. journal Proc. Natl. Acad. Sci. U.S.A. volume 99 issue 26 pages 16899 903 year 2003 pmid 12477932 doi 10.1073 pnas.242603899 pmc 139241 cite journal author Sch fer C, Steffen H, Krzykowski KJ, et al. title CRHSP 24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells. journal Am. ... more details
PBB geneid 30014 Sperm protein associated with the nucleus on the X chromosome A is a protein that in humans is encoded by the SPANXA1 gene . ref name pmid10906052 cite journal author Westbrook VA, Diekman AB, Klotz KL, Khole VV, von Kap Herr C, Golden WL, Eddy RL, Shows TB, Stoler MH, Lee CY, Flickinger CJ, Herr JC title Spermatid specific expression of the novel X linked gene product SPAN X localized to the nucleus of human spermatozoa journal Biol Reprod volume 63 issue 2 pages 469 81 year 2000 month Oct pmid 10906052 pmc doi ref ref name entrez cite web title Entrez Gene SPANXA1 sperm protein associated with the nucleus, X linked, family member A1 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 30014 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Temporally regulated transcription and translation of several testis specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer testis associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head to head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in sic spermatazoa while attempting to further define its role in spermatogenesis. ref name entrez References reflist Further reading refbegin 2 PBB F ... more details
PBB geneid 123016 Tetratricopeptide repeat domain 8 TTC8 also known as Bardet Biedl syndrome 8 is a protein that in humans is encoded by the TTC8 gene . ref name pmid14520415 cite journal author Ansley SJ, Badano JL, Blacque OE, Hill J, Hoskins BE, Leitch CC, Kim JC, Ross AJ, Eichers ER, Teslovich TM, Mah AK, Johnsen RC, Cavender JC, Lewis RA, Leroux MR, Beales PL, Katsanis N title Basal body dysfunction is a likely cause of pleiotropic Bardet Biedl syndrome journal Nature volume 425 issue 6958 pages 628 33 year 2003 month October pmid 14520415 doi 10.1038 nature02030 url ref Function TTC8 is associated with Tubulin .CE.B3 tubulin gamma tubulin , BBS4 , and PCM1 in the centrosome . ref name pmid14520415 PCM1 in turn is involved in centrosome centriolar replication during centriole Ciliogenesis ciliogenesis . ref name pmid10579718 cite journal author Kubo A, Sasaki H, Yuba Kubo A, Tsukita S, Shiina N title Centriolar satellites molecular characterization, ATP dependent movement toward centrioles and possible involvement in ciliogenesis journal J. Cell Biol. volume 147 issue 5 pages 969 80 year 1999 month November pmid 10579718 pmc 2169353 doi 10.1083 jcb.147.5.969 url ref TTC8 is located in the cilia of spermatid s, retina , and bronchiole bronchial epithelium cells. ref name pmid14520415 Clinical significance Mutations in the TTC8 gene leads to Bardet Biedl syndrome . ref name pmid14520415 ref name pmid16308660 cite journal author Stoetzel C, Laurier V, Faivre L, M garban A, Perrin Schmitt F, Verloes A, Bonneau D, Mandel JL, Cossee M, Dollfus H title BBS8 is rarely mutated in a cohort of 128 Bardet Biedl syndrome families journal J. Hum. Genet. volume 51 issue 1 pages 81 4 year 2006 pmid 16308660 doi 10.1007 s10038 005 0320 2 url ref References Reflist Further reading refbegin 2 cite journal author Nachury MV, Loktev AV, Zhang Q, et al. title A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. journal Cell volume 1 ... more details
PBB geneid 51314 Thioredoxin domain containing protein 3 TXNDC3 , also known as spermatid specific thioredoxin 2 Sptrx 2 , is a protein that in humans is encoded by the TXNDC3 gene . ref name entrez cite web title Entrez Gene thioredoxin domain containing 3 spermatozoa url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 51314 accessdate ref ref name pmid11737268 cite journal author Sadek CM, Damdimopoulos AE, Pelto Huikko M, Gustafsson JA, Spyrou G, Miranda Vizuete A title Sptrx 2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP kinase domains is expressed in human testis germ cells journal Genes Cells volume 6 issue 12 pages 1077 90 year 2001 month December pmid 11737268 doi 10.1046 j.1365 2443.2001.00484.x url issn ref Function This gene encodes a protein with an N terminus N terminal thioredoxin domain and three C terminus C terminal nucleoside diphosphate kinase nucleoside diphosphate kinase NDK domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in cilium ciliary function. ref name entrez Clinical significance Mutations in the TXNDC3 gene are associated with primary ciliary dyskinesia . ref name pmid17360648 cite journal author Duriez B, Duquesnoy P, Escudier E, Bridoux AM, Escalier D, Rayet I, Marcos E, Vojtek AM, Bercher JF, Amselem S title A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia journal Proc. Natl. Acad. Sci. U.S.A. volume 104 issue 9 pages 3336 41 year 2007 month February pmid 17360648 pmc 1805560 doi 10.1073 pnas.0611405104 url issn ref References reflist Further reading refbegin 2 cite journal author Shi D, Nakamura T, Nakajima M, et al. title Association of single nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility two case control studies in East ... more details
PBB geneid 3305 Heat shock 70 kDa protein 1L is a protein that in humans is encoded by the HSPA1L gene . ref name pmid9685725 cite journal author Ito Y, Ando A, Ando H, Ando J, Saijoh Y, Inoko H, Fujimoto H title Genomic structure of the spermatid specific hsp70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man journal J Biochem volume 124 issue 2 pages 347 53 year 1998 month Nov pmid 9685725 pmc doi ref ref name pmid9349405 cite journal author Ishihara M, Ohno S title Genetic influences on sarcoidosis series 11 journal Eye volume Pt 2 issue pages 155 61 year 1997 month Nov pmid 9349405 pmc doi ref ref name entrez cite web title Entrez Gene HSPA1L heat shock 70kDa protein 1 like url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 3305 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. ref name entrez References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Milner CM, Campbell RD title Polymorphic analysis of the three MHC linked HSP70 genes. journal Immunogenetics volume 36 issue 6 pages 357 62 year 1992 pmid 1356099 doi 10.1007 BF00218042 cite journal author Milner CM, Campbell RD title Structure and expression of the three MHC linked HSP70 genes. journal Immunogenetics volume 32 issue 4 pages 242 51 year 1990 pmid 1700760 doi 10.1007 BF00187095 cite journal author Sargent CA, Dunham I, Trowsdale J, Campbell RD ... more details
PBB geneid 23139 Microtubule associated serine threonine protein kinase 2 is an enzyme that in humans is encoded by the MAST2 gene . ref name entrez 23139 cite web title Entrez Gene MAST2 microtubule associated serine threonine kinase 2 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 23139 accessdate ref The protein encoded by this gene controls TRAF6 and NF B NF kappaB activity. ref name pmid 15308666 cite journal author Xiong H, Li H, Chen Y, et al. title Interaction of TRAF6 with MAST205 regulates NF kappaB activation and MAST205 stability. journal J. Biol. Chem. volume 279 issue 42 pages 43675 83 year 2004 pmid 15308666 doi 10.1074 jbc.M404328200 ref Interactions MAST2 has been shown to Protein protein interaction interact with PCLKC . ref name pmid12117771 cite journal last Okazaki first Noriko authorlink coauthors Takahashi Naomi, Kojima Shin Ichi, Masuho Yasuhiko, Koga Hisashi date July 2002 title Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation journal Carcinogenesis volume 23 issue 7 pages 1139 48 publisher location England issn 0143 3334 pmid 12117771 bibcode oclc id url language format accessdate laysummary laysource laydate quote doi 10.1093 carcin 23.7.1139 ref References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Walden PD, Cowan NJ title A novel 205 kilodalton testis specific serine threonine protein kinase associated with microtubules of the spermatid manchette. journal Mol. Cell. Biol. volume 13 issue 12 pages 7625 35 year 1994 pmid 8246979 doi pmc 364834 cite journal author Bonaldo MF, Lennon G, Soares MB title Normalization and subtraction two approaches to facilitate gene discovery. journal Genome Res. volume 6 issue 9 pages 791 806 year 1997 pmid 8889548 doi 10.1101 gr.6.9.791 cite journal author Walden PD, Millette CF title Increased activity associated with the MAST205 ... more details
Other uses Expert subject biology documentation date November 2008 Infobox embryology Name Embryo Latin GraySubject GrayPage Image Wrinkledfrog embryos.jpg Caption Embryos and one tadpole of the wrinkled frog Rana rugosa Image2 Caption2 MeshName MeshNumber Code Terminologia Embryologica TE E1.0.2.6.4.0.5 An embryo irregularly from Greek language Greek lang grc , plural lang grc , lit. that which grows, from en in bryein , to swell, be full the proper Latinate form would be embryum is a multicellular organism multicellular ploidy diploid eukaryote in its earliest stage of Developmental biology development , from the time of first cell division until birth , Egg biology hatching , or germination . In humans, it is called an embryo until about eight weeks after fertilisation fertilization i.e. ten weeks Gestational age Last Menstrual Period or LMP , and from then it is instead called a fetus . The development of the embryo is called embryogenesis . In organism s that sex reproduce sexually , once a spermatid sperm fertilizes an ovum egg cell , the result is a cell biology cell called the zygote , which possesses half the DNA of each of its two parents. In plant s, animal s, and some protist s, the zygote will begin to divide by mitosis to produce a multicellular organism. The result of this process is an embryo. Animal embryos In animals, the development of the zygote into an embryo proceeds through specific recognizable stages of blastula , gastrulation gastrula , and organogenesis . The blastula stage typically features a fluid filled cavity, the blastocoele blastocoel , surrounded by a sphere or sheet of cells, also called blastomere s. The embryo of a eutheria placental mammal is defined as the organism between the first cell division division of the zygote a fertilized ovum until it becomes a fetus . An ovum is fertilized in a fallopian tube through which it travels into the uterus. In humans, the embryo is defined as the product of conception after ... more details
NOTICE This list includes many synonyms, for example English, Latin and slang terms for the same thing this is intentional, please do not remove these. This is an alphabetical index of topics related to sexology , human sexuality and marriage customs, and related topics such as human sexual anatomy , reproductive biology , andrology , gynaecology , obstetrics and, where relevant, anthropology . Compact ToC side yes num yes seealso yes nobreak yes 0 9 17 beta hydroxysteroid dehydrogenase deficiency 46,XX 46,XY 47,XXX 47,XXY 47,XYY 5 alpha reductase deficiency 69 sex position 69 A Ass to mouth A2M Ass to mouth A2OGM abasiophilia abstinence, be faithful, use a condom ABC strategy Deviance sociology aberration abortifacient abortion abortion pill placental abruption abruptio placentae abstinence abstinence movement abstinence, be faithful, use a condom abstinence only sex education abstinence plus sex education acault acceleration of physical development accessory breast acmegenesis acomoclitism acquaintance rape acrosomal reaction acrosome acrotomophilia Sexual intercourse act of union Adrenocorticotropic hormone ACTH acupressure Adam s apple Substance use disorder addiction adelphic polyandry adelphogamy adipophilia adolescence adolescent gynecomastia adrenal cortex adrenal gland adrenocortical hormone adrenogenital syndrome Sex industry adult service provider adultery adulthood affinity canon law afterbirth agalmatophilia agape age disparity in sexual relationships age of consent aging and sexuality agonophilia agony aunt AIDS AIDS in Africa AIDS in Asia AIDS in India AIDS in Latin America AIDS in the United States AIDS test Alberta Eugenics Board albutophilia algolagnia algophilia alienation of affections alimony alley catting alliance theory Attractiveness allure altocalciphilia amateur pornography ambiguous genitalia ambisexual ambisexuality amelotasis amelotatist amenorrhea amenorrhoea American College of Obstetricians and Gynecologists amoebiasis amor lesbicus a ... more details
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