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Encyclopedia results for Spinal muscular atrophy

Spinal muscular atrophy





Encyclopedia results for Spinal muscular atrophy

  1. Spinal muscular atrophy (disambiguation)

    Spinal muscular atrophy is a name of a medical condition and most commonly refers to Spinal muscular atrophy SMA an autosomal recessive disorder affecting primarily proximal muscles, caused by a genetic abnormality in the SMN1 gene it includes conditions known as Werdnig Hoffman disease and Kugelberg Welander disease . Sometimes, spinal muscular atrophy is used to mean any of the following medical conditions Spinal muscular atrophy with respiratory distress type 1 SMARD1 , also known as distal spinal muscular atrophy type 1 DSMA1 a serious autosomal recessive disorder affecting primarily distal muscles, caused by a genetic defect in the chromosome 11 11q13.3 area. Spinal and bulbar muscular atrophy SBMA , also known as X linked spinal muscular atrophy type 1 SMAX1 and Kennedy s disease KD a rare X linked recessive disorder caused by a genetic defect in the chromosome X Xq11 q12 area. X linked spinal muscular atrophy type 2 SMAX2, XLSMA a rare genetic disorder affecting newborn boys. Autosomal dominant proximal spinal muscular atrophy ADSMA a very rare disorder affecting proximal muscles, caused by unknown genetic defects. Spinal muscular atrophy with pontocerebellar hypoplasia SMA PCH , also known as pontocerebellar hypoplasia type 1 PCH1 a very rare infantile disorder probably caused by a genetic defect in the VRK1 gene. Less correctly, the term spinal muscular atrophy might also be used for Distal hereditary motor and sensory neuropathy DHMN , especially of types I II Charcot Marie Tooth disease , CMD and V HSMN5 a group of rare hereditary neuropathy neuropathies affecting primarily distal muscles. See also Spinal muscular atrophies Hereditary motor and sensory neuropathy disambig ...   more details



  1. Spinal and bulbar muscular atrophy

    M, Sung JH title Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex linked ... degeneration. Spinal and bulbar muscular atrophy may share mechanistic features with other disorders ... NIH UW entry on spinal and bulbar muscular atrophy Cite web url http www.kennedysdisease.org title Kennedy ... happens. Muscular Fasciculations Twitching of muscles when at rest. Cramps Large muscle spasms. Muscular atrophy Loss of muscle bulk that occurs when the lower motor neurons do not stimulate ... lateral sclerosis ALS . See also Spinal muscular atrophies External links External links date ... to degeneration of motor neurons in the brain stem and spinal cord. Ages of onset and severity of manifestations ... motor neurons are those in the brainstem and spinal cord that directly supply the muscles. Loss of lower ... fertility Low sperm count Testicular atrophy Testicles become smaller and less functional. Miscellaneous ...   more details



  1. Spinal muscular atrophy

    name spinal muscular atrophies Infobox disease Name Spinal muscular atrophy Image Polio spinal diagram.PNG Caption Location of neurons affected by spinal muscular atrophy in the spinal cord ... pmr 62 MeshID D014897 GeneReviewsID sma GeneReviewsName Spinal Muscular Atrophy Spinal muscular ... muscle wasting atrophy . Spinal muscular atrophy manifests in various degrees of severity which ... as well, particularly in early onset forms. Spinal muscular atrophy is the most common genetic cause of infant death. The term spinal muscular atrophy is sometimes also used with relation to certain very rare hereditary disorders characterised by similar symptoms for a list see spinal muscular atrophies ... who authored several studies on the intermediate SMA phenotype. Causes Spinal muscular atrophy ... right Spinal muscular atrophy has an autosomal recessive pattern of inheritance. In SMA affected ... phenotype. ref cite pmid 19287802 ref Spinal muscular atrophy is inherited in an autosomal recessive ... 2 4 of cases. Spinal muscular atrophy affects individuals of all races, unlike other well known autosomal ... There is no known cure for spinal muscular atrophy. Palliative care Care is symptomatic. Main ... with spinal muscular atrophy author Leighton, S. journal Nutrition & Dietetics year 2003 volume 60 issue ... 10.1177 0883073807305788 Consensus Statement for Standard of Care in Spinal Muscular Atrophy which ... Sodium Phenylbutyrate in Pre symptomatic Infants With Spinal Muscular Atrophy STOPSMA accessdate 28 ... Therapeutics to advance treatment for Spinal Muscular Atrophy SMA accessdate 28 December 2011 ref In vivo ... targeting SMA can be consulted here http clinicaltrials.gov ct2 results?term spinal muscular atrophy ... USA http www.jtsma.org.uk The Jennifer Trust for Spinal Muscular Atrophy UK http www.smafoundation.org ... of motor neuron Spinal muscular atrophy with respiratory distress type 1 Spinal and bulbar muscular ... Muscular Atrophy Patient registries http www.treat nmd.eu resources patient registries national ...   more details



  1. Spinal muscular atrophy with lower extremity predominance

    about a very rare neuromuscular disorder caused by a mutation in the DYNC1H1 gene other disorders of the same type spinal muscular atrophies Spinal muscular atrophy with lower extremity predominance SMA LED OMIM OMIM2 158600 is a rare neuromuscular disorder of infants caused by a genetic mutation in the DYNC1H1 gene chromosome chromosome 14 14q32 . ref cite doi 10.1212 WNL.0b013e3182556c05 ref The condition is inheritance inherited in an autosomal dominant manner and is characterised by severe muscle atrophy which is especially prominent in legs. References references med stub neuroscience stub Category Motor neurone disease Category Nucleus diseases Category Genetic disorders by system Category Systemic atrophies primarily affecting the central nervous system ...   more details



  1. Spinal muscular atrophy with respiratory distress type 1

    about an autosomal recessive condition of newborns caused by a genetic defect in 11q13.3 area other conditions with similar name spinal muscular atrophy disambiguation Infobox Disease Name Spinal muscular atrophy with respiratory distress type 1 Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 604320 MedlinePlus eMedicineSubj eMedicineTopic MeshID Spinal muscular atrophy with respiratory distress type 1 SMARD1 or distal spinal muscular atrophy type 1 DSMA1 or hereditary motor neuropathy type VI HMN VI is a motor neurone disease involving death of motor neurons in the spinal cord and subsequent generalised atrophy of body muscles. The condition is caused by a genetic mutation in the IGHMBP2 gene . ref name pmid15290238 cite doi 10.1007 s00439 004 1156 0 ref SMARD1 is counted among distal hereditary motor neuropathies and among spinal muscular atrophies . SMARD1 is usually diagnosed at or before birth, and symptoms include intrauterine growth retardation, often premature birth, foot deformity, and a characteristic pattern of breathing the stomach draws inward with inspiration that indicates weakness of the diaphragm. Whilst symptoms may resemble a case of early spinal muscular atrophy SMA type 0 or 1, in SMA type 0 1 the diaphragm is strong and the stomach prominently protrudes with inspiration paradoxic breathing pattern . Respiratory support mechanical ventilation is required in most cases and long term prognosis is usually negative. See also Motor neuron disease Hereditary motor neuropathies Spinal muscular atrophies Spinal muscular atrophy Monomelic amyotrophy Further reading cite doi 10.1002 ana.10755 cite doi 10.1177 0883073807310989 cite doi 10.1016 j.ejpn.2011.10.005 cite doi 10.1542 peds.2011 0544 References reflist CNS diseases of the nervous system Category Motor neurone disease medicine stub ...   more details



  1. X-linked spinal muscular atrophy type 2

    about a X linked hereditary condition other conditions with similar name spinal muscular atrophy disambiguation Infobox disease Name X linked spinal muscular atrophy type 2 Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM 301830 MedlinePlus eMedicineSubj eMedicineTopic MeshID X linked spinal muscular atrophy type 2 SMAX2, XLSMA is a rare neurological disorder involving death of motor neurons in the anterior horn of spinal cord resulting in generalised muscle wasting atrophy . The disease is inherited in a X linked recessive manner from carrier mothers to affected sons and is caused by a mutation in UBE1 gene. ref name pmid18179898 cite doi 10.1016 j.ajhg.2007.09.009 ref ref name pmid17224690 cite doi 10.1097 GIM.0b013e31802d8353 ref Affected babies have general muscle weakness, weak cry and floppy limbs consequently, the condition is usually apparent at or even before birth. Symptoms resemble much more common spinal muscular atrophy SMA type 0 or 1 however, SMAX2 is caused by a different genetic defect and only genetic testing can correctly identify the disease. See also Motor neuron disease Spinal muscular atrophies Spinal muscular atrophy X linked spinal muscular atrophy type 1 References Reflist 2 CNS diseases of the nervous system X linked disorders Disorders of translation and posttranslational modification Category Systemic atrophies primarily affecting the central nervous system Category X linked recessive disorders Category Motor neurone disease Medicine stub ...   more details



  1. Progressive muscular atrophy

    have to be ruled out, such as multifocal motor neuropathy or spinal muscular atrophy . Tests ... spinal muscular atrophy . Throughout the course of the late 19th century, other conditions were ... muscular atrophy Syndrome or disease? journal Neurology. volume 70 issue 9 pages 723 727 year ... findings in sporadic progressive muscular atrophy. journal J Neurol. volume 255 issue ... MND. Prognosis The importance of correctly recognizing progressive muscular atrophy as opposed ... dysfunction in progressive muscular atrophy journal Neurology volume 67 issue 9 pages 1718 ... I, Ikeda K. title Sporadic amyotrophic lateral sclerosis of long duration mimicking spinal progressive muscular atrophy exists additional autopsy case with a clinical course of 19 years. journal Neuropathology ... SB, Shaw PJ. title Corticospinal tract degeneration in the progressive muscular atrophy variant of ALS ... muscular atrophy, progressive myopathy, progressive muscular dystrophy , peripheral neuritis ... motor neurone degeneration, the symptoms of PMA include atrophy fasciculation s muscle weakness ... Category Motor neurone disease P Category Unsolved problems in neuroscience es Atrofia muscular progresiva ...   more details



  1. Spinal muscular atrophies

    of motor neuron s, ref DorlandsDict one 000010243 spinal muscular atrophy ref ref name pmid17761647 cite doi 10.1177 0883073807305662 ref resulting in muscle weakness and muscular atrophy atrophy . The clinical spectrum of spinal muscular atrophies ranges from early infant death to normal adult ... Kennedy s disease affects primarily boys X linked spinal muscular atrophy type 2 SMAX2, XLSMA OMIM2 301830 UBE1 X chromosome Xp11.23 X linked recessive Affects newborn boys X linked spinal muscular atrophy ... of all extremities in children, slowly progressive Spinal muscular atrophy with respiratory distress ... dominant proximal spinal muscular atrophy ADSMA OMIM2 182980 VAPB Chromosome 20 20q13.32 Autosomal dominant Finkel type spinal muscular atrophy affects proximal muscles in adults Spinal muscular atrophy ... Affects proximal muscles in infants, rare Spinal muscular atrophy with pontocerebellar hypoplasia ... hypoplasia type 1 affects brain development in infants Spinal muscular atrophy with congenital ..., extremely rare Segmental spinal muscular atrophy OMIM2 183020 multiple Chromosome 18 18q21.3 ... in India and Japan Scapuloperoneal spinal muscular atrophy SPSMA OMIM2 181405 TRPV4 Chromosome ... with the severe form of spinal muscular atrophy frequently succumb to respiratory disease due to weakness ... activities to rapidly advance treatments for spinal muscular atrophy, neuromuscular disease, and other .... See also Motor neuron disease Hereditary motor neuropathies Spinal muscular atrophy Polyneuropathy ...Infobox Disease Name Spinal muscular atrophies Image Polio spinal diagram.PNG Caption Location of neurons affected in spinal muscular atrophies ICD10 ICD10 G 12 g 10 MeshID D009134 Spinal Muscular Atrophies ..., respiratory therapy, and clinical nutrition. Types The most common among muscular atrophies, spinal muscular atrophy SMA , is responsible for around 95 of cases and is caused by a mutation of the SMN1 ... non 5q spinal muscular atrophies are caused by mutations of other genes, some known and others not yet ...   more details



  1. Atrophy

    of tissue. A diminished muscular trophic is designated as atrophy . Atrophy is the general physiological ...dablink For the American thrash metal band, see Atrophy band Infobox Disease Name Atrophy Image Mouse with spinal muscular atrophy.jpg Caption Mice with spinal muscular atrophy DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D001284 Atrophy is the partial or complete wasting away of a part of the body . Causes of atrophy include mutation s which can destroy the gene ... to other disease, it is termed pathological atrophy , although it can be a part of normal body development and homeostasis as well. Atrophy examples Normal development Examples of atrophy as part of normal ... s in adolescence. Muscle atrophies main Muscle atrophy Disuse atrophy of muscle s muscle atrophy .... . This type of atrophy can usually be reversed with exercise unless severe. Astronauts in microgravity must exercise regularly to minimize atrophy of their limb muscles. There are many diseases and conditions which cause atrophy of muscle mass. For example diseases such as cancer and AIDS induce a body wasting syndrome called cachexia , which is notable for the severe muscle atrophy seen. Other syndromes or conditions which can induce skeletal muscle atrophy are congestive heart failure and liver ... function and mass. This condition is called sarcopenia , and may be distinct from atrophy in its pathophysiology ... ency article 003188.htm title Muscle atrophy publisher MedlinePlus accessdate 2007 10 02 date 2007 ... Pathologic atrophy of muscles can occur with diseases of the motor nerves, or diseases of the muscle ... . Examples of atrophying muscle diseases include muscular dystrophy , myotonia congenita , and myotonic ... fibrillation can also result in muscle atrophy. Gland atrophy The adrenal gland s atrophy during prolonged use of exogenous glucocorticoid s like prednisone . Atrophy of the breast s can occur with prolonged estrogen reduction, as with anorexia nervosa or menopause . Atrophy of the testes occurs ...   more details



  1. Muscle atrophy

    of muscular atrophy, the use of an anabolic steroid such as methandrostenolone is administered to patients ... also Brown atrophy of the heart Muscle weakness Muscular dystrophy Myotonic dystrophy References reflist External links MeshName Muscular atrophy Myopathy Category Physiology Category Medical signs ... 728.2 ICDO OMIM MedlinePlus 003188 eMedicineSubj eMedicineTopic MeshID D009133 Muscle atrophy , or disuse atrophy , is defined as a decrease in the mass of the muscle it can be a partial or complete wasting ... force is related to mass. Muscle atrophy results from a co morbidity of several common diseases ... in these disease settings have a poor prognosis . Moreover, starvation eventually leads to muscle atrophy. Disuse of the muscles will also lead to atrophy. Clinical settings of atrophy There are many diseases and conditions which cause a decrease in muscle mass, known as atrophy , including Dejerine ..., etc. Other syndromes or conditions which can induce skeletal muscle atrophy are liver disease, and starvation. Quality of life Muscular atrophy decreases quality of life as the sufferer becomes unable to perform certain tasks or worsen the risks of accidents while performing those like walking . Muscular atrophy increases the risks of falling in conditions such as IBM inclusion body myositis . Muscular atrophy affects a major number of elderly. Other muscles diseases, distinct from atrophy During ... loss of muscle mass atrophy , or the age related decrease in muscle function sarcopenia , there are other diseases which may be caused by structural defects in the muscle muscular dystrophy , or by inflammatory reactions in the body directed against muscle the myopathies . Pathophysiology Muscle atrophy ... atrophy, there is a down regulation of protein synthesis pathways, and an activation protein degradation ref Sandri M. 2008. Signaling in Muscle Atrophy and Hypertrophy. http physiologyonline.physiology.org ... pathway which seems to be responsible for much of the muscle loss seen in a muscle undergoing atrophy ...   more details



  1. Aesthetic atrophy

    Aesthetic atrophy is the diminished capacity to appreciate new or unfamiliar music or other sensory stimuli. It is typically accompanied by the sufferer s retreat to familiar and comfortable works. ref Cite news last Cizmar first Martin coauthors title The Scourge of Aesthetic Atrophy, and the Top 50 Albums of the Aughts newspaper Phoenix New Times location Phoenix, Arizona pages language publisher New Times Media date 31 December 2009 url http www.phoenixnewtimes.com 2009 12 31 music the scourge of aesthetic atrophy at the top 50 albums of the aughts 2 accessdate 2 January 2010 ref References reflist Category Aesthetics ...   more details



  1. Testicular atrophy

    unreferenced date November 2009 Testicular atrophy is a medical condition in which the male reproductive organ anatomy organ s the testes , which in humans are located in the scrotum diminish in size and may be accompanied by loss of function. This does not refer to temporary changes, such as those brought on by cold. Some medications can cause testicular atrophy. Anabolic Androgenic Steroids AAS can cause testicular atrophy by reducing the amount of luteinizing hormone LH produced by the pituitary gland. LH stimulates the testicles to produce testosterone. Testicular atrophy caused by steroid use can be prevented by taking hCG, a drug which mimics the effect of LH. However, hCG will simply address the symptoms. Endogenious levels of anabolic androgenic steroids will remain the cause, and testicular atrophy will continue until the male body regains homeostasis. It is unclear how long hCG can be administered to a male on anabolic androgenic steroids before desensitization occurs. See also Orchitis References reflist External links http www.tabexperts.com TesticularAtrophy.htm Following Inguinal Hernia repair med sign stub Category Testicle disorders de Hodenatrophie pt Atrofia testicular ...   more details



  1. Olivopontocerebellar atrophy

    Infobox disease Name Olivopontocerebellar atrophy ICD10 ICD10 G 23 8 g 20 ICD9 ICD9 333.0 ICDO Image Gray707.png Caption Sagittal section through right cerebellar hemisphere. The right olive has also been cut sagitally. OMIM MedlinePlus 000758 eMedicineSubj neuro eMedicineTopic 282 DiseasesDB 2012 DiseasesDB mult DiseasesDB2 9208 MeshID D009849 Olivopontocerebellar atrophy OPCA is a term that describes the degeneration of neurons in specific areas of the brain the cerebellum, pons, and inferior olives. ref name nidsopca cite web title NINDS Olivopontocerebellar Atrophy Information Page accessdate ... spinocerebellar ataxia known as Machado Joseph disease and Multiple system atrophy multiple system atrophy MSA , with which it is primarily associated. ref name nidsopca OPCA may also be found in the brains ... and Andr Thomas . ref WhoNamedIt synd 1903 Dejerine Thomas atrophy ref ref J. J. Dejerine, A. Thomas ... K, Fox A. 2009 Challenge oriented gait and balance training in sporadic olivopontocerebellar atrophy ... Ramos JM, Wenning GK. Olivopontocerebellar atrophy toward a better nosological definition. Mov Disord. 21 10 1607 13, 2006 . ref Hereditary Disorders The term olivopontocerebellar atrophy is currently .... ref Winkler ref Winkler, C. A case of olivo pontine cerebellar atrophy and our conceptions of neo ... uses of the term In the past, the term olivopontocerebellar atrophy extended to both the sporadic ... system atrophy , ref http www.ncbi.nlm.nih.gov entrez query.fcgi?db mesh&cmd search&term multiple system atrophy MeSH Result Bot generated title ref as well as to four hereditary types, which have ... in sporadic olivopontocerebellar atrophy a case study. J Neurol Phys Ther. 33 3 160 8. ref . The treatment ... reflist 2 External links GPnotebook 113967058 olivopontocerebellar atrophy GPnotebook 429195218 lethal olivopontocerebellar atrophy NINDS opca http www.alyshia.com opca about.html OPCA Awareness CNS diseases of the nervous system DEFAULTSORT Olivopontocerebellar Atrophy Category Brain disorders ja ...   more details



  1. Cerebral atrophy

    Unreferenced date February 2011 Infobox disease Name Cerebral degeneration ICD9 ICD9 331.9 Cerebral atrophy is a common feature of many of the diseases that affect the brain . Atrophy of any tissue means loss of cells. In brain tissue, atrophy describes a loss of neuron s and the connections between them. Atrophy can be generalized, which means that all of the brain has shrunk or it can be focal, affecting only a limited area of the brain and resulting in a decrease of the functions that area of the brain controls. If the cerebral hemispheres the two lobes of the brain that form the cerebrum are affected, conscious thought and voluntary processes may be impaired. Associated diseases and disorders The pattern and rate of progression of cerebral atrophy depends on the disease involved. Diseases that cause cerebral atrophy include age stroke and traumatic brain injury Depression mood Major depressive disorder Alzheimer s disease , Pick s disease , senile dementia , Frontotemporal dementia fronto temporal dementia , and vascular dementia cerebral palsy , in which lesions damaged areas may impair motor coordination Huntington s disease , and other genetic disorders that cause build up of toxic levels of proteins in neurons leukodystrophies, such as Krabbe disease , which destroy the myelin sheath that protects axon s mitochondrial encephalomyopathies, such as Kearns Sayre syndrome , which interfere with the basic functions of neurons multiple sclerosis , which causes inflammation, myelin damage, and lesions in cerebral tissue infectious diseases , such as encephalitis , neurosyphilis , and AIDS , in which an infectious agent or the inflammatory reaction to it destroys neurons and their axons epilepsy , in which lesions cause abnormal electrochemical discharges that result in seizures ... diseases that cause cerebral atrophy are associated with dementia, seizure s, and a group of language ... system DEFAULTSORT Cerebral Atrophy Category Gross pathology de Hirnatrophie ta ...   more details



  1. Atrophy (band)

    Infobox musical artist See Wikipedia WikiProject Musicians name Atrophy image caption image size background group or band alias origin Tucson, Arizona , USA genre Thrash metal years active 1986&ndash 1990 label Roadrunner Records Roadrunner associated acts website http www.roadrunnerrecords.com theVault artist.aspx?artist id 102841 Roadrunner Records Archive current members past members James Gulotta br Tim Kelly br Chris Lykins br Rick Skowron br Brian Zimmerman notable instruments Atrophy was a thrash metal band formed in Tucson, Arizona , USA by Chris Lykins, James Gulotta, and Brian Zimmerman. The original bandname was Heresy, but by the time the band was rounded out to its professional line up &ndash with Tim Kelly and Rick Skowron joining the fold &ndash the name was changed. In 1987, the band produced two cassette demos and were subsequently picked up by major thrash metal specialist label, Roadrunner Records . They recorded two albums &ndash Socialized Hate in 1988, and Violent By Nature in 1990 &ndash and toured the USA and Europe with fellow Arizonans Sacred Reich and Switzerland Swiss band, Coroner band Coroner . Following the European tour, Chris Lykins left the band to go to medical school. The band attempted to carry on with new members and even got so far as making a pre production tape for a third album, but Roadrunner Records lost confidence in the band &ndash Chris Lykins was one of the main songwriters &ndash and they were dropped by the label as a consequence. ref http www.metalwhore.com main index.php?option com content&task view&id 135&Itemid 58 ref Tim Kelly and James Gulotta went on to form a band called Head Circus, which Rick Skowron is also a member ... links http www.roadrunnerrecords.com theVault artist.aspx?artist id 102841 Atrophy at Roadrunner Records DEFAULTSORT Atrophy Category Musical groups established in 1986 Category Musical groups disestablished ... of Tucson, Arizona US metal band stub de Atrophy it Atrophy nl Atrophy ...   more details



  1. Steroid atrophy

    The following discusses Corticosteroid induced dermal atrophy. File atrophied skin.png thumb Lower arm of a 47 year old female showing skin damage due to topical steroid use Steroid atrophy is a potential ... atrophy exists whenever topical corticosteroids are used, even with low potency steroids . Skin atrophy , along with other undesirable side effects such as telangectasia and striae , can appear as quickly ... skin . ref name medscape cite web title Steroid Atrophy url http www.medscape.com viewarticle ... atrophy of the skin. ref cite web title Topical steroid action url http www.drmakise.com ... evidence of dermal atrophy is a reduction in the diameter of the fibrils and then the collagen ... irreversible atrophy , while atrophy induced by short term use may to some extent be reversible except for striae . ref name llogo cite web title The repairing effect of Vivida on skin atrophy induced ... skin atrophy consists of a reduction in epidermal and dermal thickness, regression of the sebaceous glands, subcutaneous fat loss, and muscle layer atrophy. These changes are typically observed following ... that lasts up to 3 days. Even low potency topical steroids can cause slight skin atrophy that often reverses upon discontinuation of the drugs. Atrophy and striae are of concern on areas of the skin ... mild atrophy and telangiectasia might be reversible upon discontinuation of corticosteroids, overtly ... induced atrophy and are resistant to treatment. ref cite journal first1 Patricia last1 Ting title ... 0846.2001.70203.x title Corticosteroid induced atrophy and barrier impairment measured by non invasive ... aged skin and those of corticosteroid induced chronic atrophy of the skin are partially very .... However, in chronologically aged skin striae are not observed, while in corticosteroid atrophy .... Steroid atrophy is often permanent though, if caught soon enough and the topical corticosteroid ... atrophy of the skin. ref name llogo ref cite journal doi 10.3109 09546639509080586 title Treatment ...   more details



  1. Muscular dystrophy

    Infobox disease Name Muscular dystrophy Image Caption DiseasesDB ICD10 ICD10 G 71 0 g 70 ICD9 ICD9 359.0 ... Muscular dystrophy MD is a group of muscle diseases that weaken the musculoskeletal system and hamper ... conditions factsheets duchenne.html Muscular Dystrophy Campaign Retrieved 9 April 2007. ref Muscular ... Emery AE title The muscular dystrophies journal Lancet volume 359 issue 9307 pages 687 695 year 2002 ... Duchenne muscular dystrophy . It soon became evident that the disease had more than one form. The other major forms are Becker s muscular dystrophy Becker , limb girdle muscular dystrophy limb girdle , Congenital muscular dystrophy congenital , Facioscapulohumeral muscular dystrophy facioscapulohumeral , Myotonic muscular dystrophy myotonic , Oculopharyngeal muscular dystrophy oculopharyngeal , Distal muscular dystrophy distal , and Emery Dreifuss muscular dystrophy Emery Dreifuss muscular dystrophy ... major types of muscular dystrophy listed above, several MD like conditions have also been identified ... http psycnet.apa.org journals bul 86 2 250 ref Signs and symptoms Progressive muscular wasting Poor balance Drooping eyelids atrophy Scoliosis curvature of the spine and the back Inability to walk Frequent ... muscular dystrophies follow various inheritance patterns. However, mutations of the dystrophin ... inadequacy in adults with muscular dystrophy. Muscle Nerve. 2005 31 6 713 8. ref The main cause of the Duchenne and Becker types of muscular dystrophy is the muscle tissue s cytoskeletal impairment ... in two ways mechanical stabilisation and regulated calcium levels. Diagnosis The diagnosis of muscular ... history will help the doctor determine the type of muscular dystrophy. Specific muscle groups are affected by different types of muscular dystrophy. Often, there is a loss of muscle mass wasting , which may be hard to see because some types of muscular dystrophy cause a build up of fat and connective ... . Management There is no known cure for muscular dystrophy, although significant headway ...   more details



  1. Muscular lacuna

    Context date October 2009 The Muscular lacuna Latin lacuna musculorum is the lateral compartment beneath the inguinal ligament , for the passage of the iliopsoas muscle and femoral nerve it is separated by the iliopectineal arch from the vascular lacuna . Category Muscular system anatomy stub Muscles of abdomen b ...   more details



  1. Muscular system

    pp protected small yes Cleanup weighted date December 2011 Infobox Anatomy Name Muscular system Latin systema musculare GraySubject GrayPage Image Muscles anterior labeled.png Caption Muscles anterior labeled Image2 Muscle posterior labeled.png Caption2 Muscle posterior labeled Precursor System Artery Vein Nerve Lymph MeshName MeshNumber The muscular system is an organ anatomy organ system consisting of skeletal muscle skeletal , smooth muscle smooth and cardiac muscle cardiac muscle s. It permits movement of the body, maintains posture, and circulates blood throughout the body. The muscular system in vertebrate s is controlled through the nervous system , although some muscles such as the cardiac muscle can be completely autonomous. Muscles Main Muscle There are three distinct types of muscles skeletal muscles, cardiac or heart muscles, and smooth non striated muscles. Muscles provide strength, balance, posture, movement and heat for the body to keep warm. Upon stimulation by an action potential , skeletal muscles perform a coordinated contraction by shortening each sarcomere. The best proposed model for understanding contraction is the sliding filament model of muscle contraction. Actin and myosin fibers overlap in a contractile motion towards each other. Myosin filaments have club shaped heads that project toward the actin filaments. Larger structures along the myosin filament ... and the cervical vertebrae lateral sacral artery posterior branch of spinal nerve extends the vertebral ... of the cerebellum of the brain. This allows for complex muscular coordination with little conscious ... of ATP in muscle System and organs muscular system Category Muscular system als Muskulatur ar ... muscular cs Pohybov soustava cy System gyhyrol de Muskulatur dv el es Sistema muscular eu Gihar sistema fr Syst me musculaire gl Sistema muscular hi id Sistem ... no Muskelsystem pl Uk ad mi niowy pt Sistema muscular ro Sistemul muscular ru ...   more details



  1. Most Muscular

    File Dexter Jackson IFBB 2008 Australia 3.jpg thumb A most muscular pose. The Most Muscular is a common bodybuilding pose, often used to highlight as much of a contestant s muscle repertoire as possible by demonstrating the maximum mass of muscle to the judging panel. All front facing muscles should be showcased since the contestant forces their hands together at the same time as contracting the pectoralis major muscle pectorals , obliques, deltoid muscle anterior deltoids , biceps , forearm s and abdominals . The quadriceps muscle quadriceps and calf muscle calves should also be flexed if at all possible. External links wiktionary most muscular http www.bodybuilding.com fun bbinfo.php?page PosingandFlexing Bodybuilding.com Posing and Flexing Category Bodybuilding ...   more details



  1. Muscular Salamander

    This article was auto generated by User Polbot . Taxobox name Muscular Salamander image status NT status system IUCN3.1 regnum Animalia phylum Chordata classis Amphibia ordo Caudata familia Plethodontidae genus Pseudoeurycea species P. papenfussi binomial Pseudoeurycea papenfussi binomial authority https www.esm.harvard.edu faculty hanken public html documents Parra Olea 20et 20al 202005 20Copeia.pdf Parra Olea, Garc a Par s, Hanken & Wake, 2005 synonyms The Muscular Salamander or Salamandra Escaladora Pseudoeurycea papenfussi is a species of salamander in the Plethodontidae family. It is Endemism endemic to Mexico . Its natural habitat s are subtropical or tropical dry forest s and rocky areas. It is threatened by habitat loss . Source Hanken, J. & Wake, D. 2006. http www.iucnredlist.org search details.php 61910 all Pseudoeurycea papenfussi . http www.iucnredlist.org 2006 IUCN Red List of Threatened Species. Downloaded on 23 July 2007. Category Fauna of Mexico Category Pseudoeurycea Plethodontidae stub es Pseudoeurycea papenfussi fr Pseudoeurycea papenfussi pt Pseudoeurycea papenfussi vi Muscular Salamander ...   more details



  1. Muscular Christianity

    File Muscular Christianity Gruger.jpg thumb right Illustration by Frederick R. Gruger F. R. Gruger for the novel ... no pride . Muscular Christianity is a Christian commitment to piety and physical health, basing ... muscular christianity evangelism&hl en&sa X&ei FwVuT7rqG Tr0gHG6 2zBg&ved 0CHEQ6AEwCA v onepage&q muscular ... that has become the keystone of muscular Christianity. ref ref cite books author David P. Setran ... books?id pHs0QJXYBNEC&pg PA134&dq muscular christianity evangelism&hl en&sa X&ei jwNuT WYHYfV0QHiqPW1Bg&ved 0CHoQ6AEwCQ v onepage&q muscular 20christianity 20evangelism&f false publisher Palgrave Macmillan quote While the shift to a character oriented evangelism clearly represented muscular ... Encyclop dia url http books.google.com books?id jWj5OBvTh1IC&pg PA557&dq muscular christianity&hl en&sa X&ei Y htT zGFKXg0QGChZX Bg&ved 0CDsQ6AEwAjgU v onepage&q muscular 20christianity&f false publisher ABC CLIO quote Muscular Christianity can be defined as a Christian commitment to health ... Christian ideals in personal life and Christianity and politics politics . Muscular Christianity ... Perspective url http books.google.com books?id O6j6joobFCIC&pg PA365&dq Muscular Christianity Athletes in Action v onepage&q Muscular 20Christianity 20Athletes 20in 20Action&f false quote Muscular ... s Dangerous Idea url http books.google.com books?id KQzhEclsl94C&pg PT380&dq Muscular Christianity Athletes in Action v onepage&q Muscular 20Christianity 20Athletes 20in 20Action&f false quote Nor is sport a purely Protestant concern Catholicism can equally well be said to promote muscular Christianity ...&dq muscular christianity protestantism catholicism v onepage&q&f false quote As neo orthodoxy arose in the mainline Protestant churches, Muscular Christianity declined there. It did not, however, disappear ... Muscular Christianity in the athletic programs of schools such as Notre Dame, as do evangelical Protestant ... 4.8. A mural in a YMCA emphasizing godliness and physical health . Muscular Christianity can ...   more details



  1. Muscular layer

    Infobox Anatomy Name Muscular layer Latin tunica muscularis GraySubject GrayPage Image Ens.png Caption LAYERS Muscular layer includes the 2nd through 4th layers BR Serous membrane serosa BR Muscular coat longitudinal muscle BR Auerbach s plexus myenteric plexus BR Muscular coat circular muscle BR Submucous plexus submucosal plexus BR submucosa l BR Mucous membrane mucosal Image2 Gray1134.png Caption2 Transverse section of ureter . System MeshName MeshNumber DorlandsPre t 22 DorlandsSuf 12832129 The muscular coat muscular layer , muscular fibers , muscularis propria , muscularis externa is a region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis . It usually has two distinct layers of smooth muscle inner and circular outer and longitudinal However, there are some exceptions to this pattern. In the stomach and colon, there are three layers to the muscularis externa. In the upper esophagus , part of the externa is skeletal muscle , rather than smooth muscle. The inner layer of the muscularis externa forms a sphincter at two locations of the alimentary canal in the pyloric stomach , it forms the pyloric sphincter in the anal canal , it forms the anal sphincter Additional images gallery Image Illu ureters wall.jpg Wall of the ureter. Image Illu stomach layers.jpg Layers of stomach wall. Image Gray1033.png Section of the human esophagus . Moderately magnified. Image Gray1058.png Section of duodenum of cat. X 60. Image Gray1141.png Vertical section of bladder wall. gallery External links eMedicineDictionary muscular layer http science.nhmccd.edu BioL urinary bladder2.htm Histology at nhmccd.edu BiowebUW APLab Table of Contents Lab 12 Colon 1 Colon 1e colon 1e.html Muscularis externa of the colon BiowebUW zoolab Table of Contents Lab 1b Cross section of the small int Smooth muscle layers smooth muscle layers.htm Smooth muscle layers of the gut OklahomaHistology 52 05 Duodenum UCDavisOrganology ...   more details



  1. Muscular Development

    Infobox Magazine title Muscular Development Deleted image removed Image MDlogo.JPG deletable image caption 1 Saturday, 3 November 2007 image size 200px image caption Muscular Development logo. editor flagicon USA David Zinczenko editor title John Romano frequency 12 times a year circulation category bodybuilding company publisher firstdate 1964 country United Kingdom , United States language English language English website http www.musculardevelopment.com Official Website issn Deleted image removed Image Victor Martinez.jpeg thumb right Victor Martinez on the cover of Muscular Development magazine Muscular Development is an USA American fitness and bodybuilding magazine first published in 1964. It was founded by Bob Hoffman History Bob Hoffman athlete, nutritionist, weightlifter, coach and philanthropist was born on a farm in Tifton, Georgia on Nov 9th 1898. His family stock was good. Bob was never the seven stone weakling claimed by other physical culturists. His father was a large strong man who liked to demonstrate the hardness of his tensed muscles. Given this it his easy to see how Bob was influenced in his formative years. When Bob was 5 years old the family moved to Wilkinsburg near Pittsburgh where his athletic career started from a very young age. He was an exceptional athlete especially in aquatic sports his favorite being canoeing. The First World War saw Bob as a hero. He gained 3 Croix de Guerres with two palms and a Silver Star from France. From Belgium he was awarded ... Muscular Development Romanian website , muscular.ro, accessed January 17, 2007. ref MD , as it s known to many of its readers, was previously owned by Twinlab . In 2001 Twinlab sold Muscular Development ... musdev musdev.htm Muscular Development , getbig.com, accessed January 17, 2007. ref Muscular Development ... Two covers featuring Max Rep image1 caption1 Max Rep & Sandy Riddell Jan. 1991 image2 Muscular Development 1993 November Vol 30, Num 11.jpg caption2 Max Rep & Quadra Blu Nov. 1993 Muscular Development ...   more details



  1. Muscular hydrostat

    Image que lengua.jpg thumb right The tongue is a muscular hydrostat A muscular hydrostat is a biological ... movement without fluid in a separate compartment, as in a hydrostatic skeleton . A muscular hydrostat ... filled cavity, a muscular hydrostat is composed mainly of muscle tissue. Since muscle tissue itself is mainly made of water and is also effectively incompressible, similar principles apply. Muscular ... Muscles provide the force to move a muscular hydrostat. Since muscles are only able to produce ... in a muscular hydrostat are oriented in three different directions parallel to the long axis, perpendicular ... the central core of musculature. Mechanism of operation In a muscular hydrostat, the musculature ... important biomechanical feature of a muscular hydrostat is its constant volume. Muscle is composed .... In a muscular hydrostat or any other structure of constant volume, a decrease in one dimension will cause ..., bending and torsion in muscular hydrostats all depend on constancy of volume to effect ... in chameleons II. Role of shape change in a muscular hydrostat . The Journal of Experimental Biology ... musculature arrangements. Given the constant volume of muscular hydrostats, these contractions cause ... in the African pig nosed frog Hemisus marmoratum a muscular hydrostatic model http jeb.biologists.org ... Squids have been shown to use muscular hydrostat elongation in prey capture and feeding as well. ref name Kier1982 Bending The bending of a muscular hydrostat can occur in two ways, both of which require ... muscle will produce little or no bending and will serve to increase the diameter of the muscular ... of transverse, radial, or circular muscles to maintain a constant diameter. Bending of a muscular ... on one side of the structure. The bending of a muscular hydrostat is particularly important in animal ...1989 Stiffening The stiffening of a muscular hydrostat is accomplished by the muscle or connective ... been proposed to be a muscular hydrostat in which stiffening provides an important function. ref ...   more details




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