Infobox Disease Name Splenicdisease Image Spleen hyaloserositis b high mag.jpg Caption Micrograph of a spleen with hyaloserositis . H&E stain . DiseasesDB ICD10 ICD10 D 73 d 70 , ICD10 Q 89 0 q 80 ICD9 ICD9 289.4 ICD9 289.5 ICD9 759.0 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D013158 Splenic diseases include splenomegaly , where the spleen is enlarged for various reasons. On the other hand, a lack of normal spleen function is called asplenia . Splenomegaly Main Splenomegaly Enlargement of the spleen is known as splenomegaly . It may be caused by sickle cell anemia , sarcoidosis , malaria , bacterial endocarditis , leukemia , pernicious anemia , Gaucher s disease , leishmaniasis , Hodgkin s disease , Banti s syndrome Banti s disease , hereditary spherocytosis , cyst s, glandular fever Infectious mononucleosis mononucleosis or Mono caused by the Epstein Barr Virus , and tumour s. Primary tumors of the spleen include hemangioma s and hemangiosarcoma s. Marked splenomegaly may result in the spleen occupying a large portion of the left side of the abdomen. The spleen is the largest collection of lymphoid tissue in the body. It is normally palpable in preterm infants, in 30 of normal, full term neonates , and in 5 to 10 of infants and toddlers . A spleen easily palpable below the costal margin in any child over the age of 3 4 years should be considered abnormal until proven otherwise. Splenomegaly can result from antigenic stimulation e.g., infection , obstruction of blood ... , or infiltration e.g., leukemia or storage disease, such as Gaucher s disease . The most common cause ... this is rare. Sickle cell disease can cause a functional asplenia or autosplenectomy by causing infarction ... spherocytosis , etc. , certain forms of lymphoma or for the removal of splenic tumors or cysts. See also Ruptured spleen Polysplenia Splenic infarction Hyaloserositis of the spleen sugar coated spleen ... blood disorders spleen disorders overview of the spleen.html Lymphatic organ disease Congenital ... more details
Infobox disease Name Splenic infarction Image Splenic infarction.png Caption Two large splenic infarcts ... clot formation feature in this condition. In sickle cell disease, repeated splenic infarctions lead to a non function spleen autosplenectomy . Any factor that directly compromises the splenic artery ... eMedicineTopic 193718 MeshID D013159 In medicine , splenic infarction is a condition in which oxygen ... RE title The natural history of splenic infarction journal Surgery volume 100 issue 4 pages 743 50 year 1986 month October pmid 3764696 doi url ref Splenic infarction occurs when the splenic artery ... C, Seifart U, G rg K title Acute, complete splenic infarction in cancer patient is associated with a fatal ... HV, Sheedy PF, Edwards WD title Thromboembolic splenic infarction journal Mayo Clin. Proc. volume 61 ... journal author Frippiat F, Donckier J, Vandenbossche P, Stoffel M, Boland B, Lambert M title Splenic ... Salvi PF, Stagnitti F, Mongardini M, Schillaci F, Stagnitti A, Chirletti P title Splenic infarction ... EH, Morgenstern L, Hiatt JR title The clinical spectrum of splenic infarction journal Am Surg ... a ruptured spleen , hemorrhage , splenic abscess for example, if the underlying cause is endocarditis ... A, Harris L, Liang HG title Traumatic cysts of the spleen the role of cystectomy and splenic ... T, Mukae M, et al. title Splenic infarction after Epstein Barr virus infection in a patient with hereditary ... cite journal author Bonnard P, Guiard Schmid JB, Develoux M, Rozenbaum W, Pialoux G title Splenic ... name pmid18171204 cite journal author Florescu D, Sordillo PP, Glyptis A, et al. title Splenic infarction ... G, Laws HJ, et al. title Splenic infarction in a patient hereditary spherocytosis, protein C deficiency ... include atrial fibrillation , patent foramen ovale , endocarditis or cholesterol embolism . Splenic ... disorder s. Other causes of splenomegaly for example, Gaucher disease or hemoglobinopathy hemoglobinopathies can also predispose to infarction. Splenic infarction can also result from ... more details
Infobox disease Name Splenic tumor Image Alt Caption DiseasesDB ICD10 C26.1, D13.9 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID A splenic tumor is a rare form of tumor that may be malignant or benign. Malignant forms include lymphoma and sarcoma . ref name Bisset2008 cite book author Bisset title Differential Diagnosis in Abdominal Ultrasound, 3 e url http books.google.com books?id pw5uaOu7PJEC&pg PT208 accessdate 22 May 2011 date 1 January 2008 publisher Elsevier India isbn 9788131215746 pages 208 ref Lymphoma is the most common malignant splenic tumor. ref name DalrympleLeyendecker2009 cite book author1 Neal C. Dalrymple author2 John R. Leyendecker author3 Michael Oliphant title Problem Solving in Abdominal Imaging url http books.google.com books?id JeaQXWu7Sz0C&pg PA410 accessdate 22 May 2011 date 12 June 2009 publisher Elsevier Health Sciences isbn 9780323043533 pages 410 ref References reflist Lymphatic organ neoplasia Category Lymphatic organ neoplasia Category Hematopathology Category Lymphoma medicine stub ... more details
Infobox Anatomy Name PAGENAME Latin hilum splenicum GraySubject 278 GrayPage 1282 Image Gray1188.png Caption The visceral surface of the spleen. Splenic hilum visible but not labeled. Image2 Caption2 Precursor System Artery Vein Nerve Lymph MeshName MeshNumber DorlandsPre h 11 DorlandsSuf 12422640 The Splenic hilum is a location on the surface of the spleen . It is the point of attachment for the gastrosplenic ligament , and the point of insertion for the splenic artery and splenic vein . Structures that enter or leave the hilum are Splenic artery Splenic vein Lymphatic vessels Nerves See also Hilum anatomy External links medcyclopaedia ii s SPLENIC HILUM Lymphatic system Category Spleen anatomy it Ilo della milza ja ... more details
Infobox Vein Name PAGENAME Latin vena lienalis GraySubject 174 GrayPage 681 Image Bilebladder.png Caption The portal vein and its tributaries. Spleen is at far right, and lienal vein is visible traveling from it to the left. Image2 3D rendered CT of abdominal aortic branches and kidneys.svg Caption2 3D rendered x ray computed tomography computed tomography , showing splenic vein at upper right. DrainsFrom trabecular vein of spleen Source short gastric veins , left gastroepiploic vein , pancreatic veins , superior mesenteric vein DrainsTo hepatic portal vein Artery splenic artery MeshName Splenic Vein MeshNumber A07.231.908.670.730 DorlandsPre DorlandsSuf In anatomy , the splenic vein in the past called the lienal vein is the blood vessel that drains blood from the spleen . It joins with the superior mesenteric vein , to form the hepatic portal vein and follows a course Anatomical terms of location Superior and inferior superior to the pancreas , alongside of the similarly named artery, the splenic artery . Unlike the splenic artery, the splenic vein is intraperitoneal as it courses along the superior border of the body of the pancreas, whereas the splenic artery is retroperitoneal . It collects branches from the stomach and pancreas and most notably from the large intestine , which is drained by the superior mesenteric vein and joins with splenic vein shortly before it forms the portal vein. Additional images gallery Image Abdominal cavity.jpg Splenic vein Image Gray1189.png Transverse section of the spleen , showing the trabecular tissue and the splenic vein and its tributaries . Image Gray1099.png The pancreas and duodenum from behind. gallery External links GraySubject 278 The Spleen GPnotebook 1241120742 Splenic vein thrombosis SUNYAnatomyLabs 39 10 01 02 Intestines and Pancreas Structures Posterior to the Pancreas SUNYAnatomyImage 8 6 85 NormanAnatomy pancreas NormanAnatomyFig pancreasvessels http www.medterms.com script main art.asp?articlekey 9909 Splenic vei ... more details
Posterior Gastric Vein splenic vein Supplies spleen MeshName Splenic Artery MeshNumber A07.231.114.814 DorlandsPre a 61 DorlandsSuf 12156021 In anatomy , the splenic artery in the past called the lienal ... . Branches The splenic artery gives off branches to the stomach and pancreas before reaching the spleen. class wikitable Branch Description Pancreatic branches of splenic artery branch to the pancreas ... gastric posterior of stomach , gastric region superior to the splenic artery Note that the branches of the splenic artery do not reach all the way to the lower part of the greater curvature of the stomach ... Along its course, it is accompanied by a similarly named vein, the splenic vein , which drains into the portal vein . Pathology Splenic artery aneurysm s are rare ref Abbas , but still the third most ... section of the human spleen , showing the distribution of the splenic artery and its branches. Image ... PC, Hallett JW, Bower TC, Panneton JM, Cherry KJ Splenic artery aneurysms two decades experience ... M, Ruptured splenic artery aneurysm, URL http www.kfshrc.edu.sa annals 215 216 01 094.htm, Accessed ... annals 215 216 01 094.htm Ruptured splenic artery aneurysm a case report from Saudi Arabia. http www.medterms.com script main art.asp?articlekey 9357 Splenic artery medterms.com GraySubject 278 The Spleen SUNYAnatomyLabs 38 05 01 01 Stomach, Spleen and Liver The Splenic Artery SUNYAnatomyImage 8 ... more details
Infobox Anatomy Name Splenic flexure Latin flexura coli sinistra GraySubject 249 GrayPage 1180 Image Illu colorectal anatomy.jpg Caption Colorectal anatomy. Splenic flexure labeled at upper right. Image2 Gray1098.png Caption2 Front of abdomen, showing surface markings for liver, stomach, and great intestine. The duodenum and pancreas. Left colic flexure labeled at upper right. Precursor Midgut hepatic , hindgut splenic System MeshName MeshNumber DorlandsPre DorlandsSuf The splenic or left colic flexure is a sharp bend between the Transverse colon transverse and the Descending colon descending Colon anatomy colon in the left upper quadrant of humans. The left colic flexure is near the spleen , and hence called the splenic flexure. There are two colic flexures in the transverse colon &mdash the other being the hepatic flexure , as it is next to the liver , in the right upper quadrant abdomen right upper quadrant . The splenic flexure is a watershed region as it receives dual blood supply from the terminal branches of the superior mesenteric artery and the inferior mesenteric artery , thus making it prone to ischemic damage in cases of hypotension because it does not have its own primary source of blood. ref First Aid for the USMLE Step 1, 2011 Edition, p.311 ref Additional images gallery Image illu intestine.jpg Intestines Image DCBE.jpg Double Contrast Barium Enema Using Positive and Negative Contrast gallery See also Splenic flexure syndrome References references External links SUNYCrossSection ThoraxF03 20 eMedicineDictionary left colic flexure SUNYAnatomyLabs 37 13 02 03 Digestive tract Category Colon anatomy Digestive stub it Flessura splenica pl Zagi cie ledzionowe okr nicy ... more details
Infobox Nerve Name PAGENAME Latin plexus splenicus GraySubject 220 GrayPage 986 Image Gray848.png Caption The celiac ganglia with the sympathetic plexuses of the abdominal viscera radiating from the ganglia. Lienal plexus labeled at upper right. Image2 Caption2 Innervates spleen BranchFrom BranchTo MeshName MeshNumber DorlandsPre p 24 DorlandsSuf 12648451 The splenic plexus lienal plexus in older texts is formed by branches from the celiac plexus , the left celiac ganglion , and from the right vagus nerve . It accompanies the lienal artery to the spleen , giving off, in its course, subsidiary plexi along the various branches of the artery. External links eMedicineDictionary splenic 28nervous 29 plexus Gray s Autonomic Category Nervous system Category Neuroanatomy ... more details
Orphan date September 2010 Splenic aspiration is the removal of fluid from the spleen , often with the use of a fine needle. It is rarely practiced in modern medicine. ref name Haferlach Cite book author Begemann, Herbert L ffler, Helmut Rastetter, Johann Haferlach, Torsten authorlink coauthors title Atlas of Clinical Hematology date publisher Springer location isbn 3 540 21013 X pages 6 ref It is indicated only in cases of hypersplenism , or other cases of unexplained spleen enlargement. The Moeschlin technique is a common technique for performing a splenic aspiration. References Reflist Category Hematology Medical stub ... more details
Orphan date May 2010 One source date May 2010 Splenic lymphoma with villous lymphocytes is a rare type of lymphoma that involves mature B cells . Older names include lymphoma simulating hairy cell leukemia and lymphoplasmacytic lymphoma with circulating villous lymphocytes . ref name pmid11079033 cite journal author Wu ML, Kwaan HC, Goolsby CL title Atypical hairy cell leukemia journal Arch. Pathol. Lab. Med. volume 124 issue 11 pages 1710 3 year 2000 month November pmid 11079033 doi url http journals.allenpress.com jrnlserv ?request get abstract&issn 0003 9985&volume 124&page 1710 ref Whether this condition is identical to splenic marginal zone lymphoma , or only highly similar, is a matter of debate. References Reflist DEFAULTSORT Splenic Lymphoma With Villous Lymphocytes Category Rare cancers disease stub ... more details
Splenic flexure syndrome is a term sometimes used to describe bloating , colic muscle spasm s of the colon, and upper abdominal discomfort thought to be caused by trapped gas at the splenic as opposed to hepatic flexure in the colon anatomy colon the pain caused can be excruciating and debilitating, and may mimic that of a heart attack because of the proximity of the splenic flexure to the heart . Some physicians classify splenic flexure syndrome as a type of Irritable bowel syndrome IBS others consider it a separate condition. External links http www.myelectronicmd.com get reference.php?Id 800&condition SPLENIC 20FLEXURE 20SYNDROME&symname S&typ 8 Splenic Flexure Syndrome at MyElectronicMD. Category GI tract disorders ... more details
Infobox disease Name Splenic marginal zone lymphoma Image Caption DiseasesDB ICD10 ICD9 ICD9 200.3 ICDO ICDO 9689 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Splenic marginal zone lymphoma SMZL is a lymphoma made up of B cells that replace the normal architecture of the white pulp of the spleen . The neoplastic cells are both small lymphocytes and larger, transformed blasts , and they invade the mantle zone of splenic lymph follicle follicles and erode the marginal zone , ultimately invading the red pulp of the spleen. Frequently, the bone marrow and splenic hilum anatomy hilar lymph ... small lymphocytic lymphoma Working Formulation small lymphocytic lymphoma FAB splenic lymphoma ... B cell with an unknown degree of differentiation. ref name who1 Diagnosis With splenic involvement ... author Melo JV, Hegde U, Parreira A, Thompson I, Lampert IA, Catovsky D title Splenic B cell lymphoma ... mol1 cite journal author Mollejo M title Splenic marginal zone lymphoma a distinctive type of low grade ... centers in splenic white pulp are replaced by small neoplastic lymphocytes that efface the mantle zone ... similar to what is observed in the splenic hilum anatomy hilar lymph nodes . ref name fra1 ... a possible hallmark of splenic lymphoma journal Histopathology volume 29 issue 6 pages 571 5 year ... of splenic lymphoma with villous lymphocytes journal Blood volume 84 issue 11 pages 3828 ... D title The immunophenotype of splenic lymphoma with villous lymphocytes and its relevance to the differential ... in splenic marginal zone lymphoma journal Mod. Pathol. volume 11 issue 7 pages 601 6 year 1998 month ... L, Spencer J, Isaacson PG title Analysis of immunoglobulin genes in splenic marginal zone lymphoma suggests ... author Corcoran MM title Dysregulation of cyclin dependent kinase 6 expression in splenic marginal ... Less than 1 of all lymphomas are splenic marginal zone lymphomas ref name arm1 cite journal author ... Splenic Marginal Zone Lymphoma Category Lymphoma ... more details
Refimprove date February 2012 Infobox television episode Title The Disease Image File ST VOY The Disease.jpg 270px Caption Harry Kim becomes intimate with Varro scientist Tal. Series Star Trek Voyager Season 5 Episode 17 Production 210 Airdate Startdate 1999 02 24 Teleplay Michael Taylor screenwriter Michael Taylor Story Kenneth Biller Director David Livingston director David Livingston Music Dennis McCarthy composer Dennis McCarthy Guests Musetta Vander Tal Charles Rocket Jippeq Prev Dark Frontier Next Course Oblivion Star Trek Voyager Course Oblivion Episode list List of Star Trek Voyager episodes List of Star Trek Voyager episodes NOTOC for an abnormal condition affecting the body of an organism Disease The Disease is the 111th episode of Star Trek Voyager , the 17th episode of the fifth season. The episode had an average rating of 4.2 5 on the official Star Trek website as of August 23, 2007 . ref cite web publisher StarTrek.com url http www.startrek.com startrek view series VOY episode 104851.html title The Disease accessdate 2007 08 23 ref Plot Voyager stops to assist a xenophobic species known as the Varro. This species lives on a Generation ship generational ship which has housed them for 400 years. While the crew works on the Varro ship, Voyager is infested with synthetic ship eating parasites that had been released on the Varro ship by dissident Varro. Meanwhile, Harry Kim Star Trek Harry Kim becomes intimate with Varro scientist Tal, and develops a physiological bond with her, one that is standard in the Varro. The physiological connection alters his behavior and sways him from his duties aboard Voyager . It is later revealed that Tal is one of the separatists. There has been a rumour of a minority of Varro that want off the ship. The parasites that Tal helped create were made to separate the individual pods of the Varro ship without destroying the ship itself ... Star Trek DEFAULTSORT Disease, The Category Star Trek Voyager episodes Category 1999 television episodes ... more details
Infobox Lymph Name Splenic lymph nodes Latin nodi lymphoidei splenici GraySubject 180 GrayPage 706 Image Gray613.png Caption Lymphatics of stomach, etc. Image2 Gray614.png Caption2 Lymphatics of stomach, etc. The stomach has been turned upward. DrainsFrom Source DrainsTo celiac lymph nodes MeshName MeshNumber Dorlands DorlandsID The splenic lymph nodes or pancreaticolienal accompany the lienal splenic artery, and are situated in relation to the posterior surface and upper border of the pancreas one or two members of this group are found in the gastrolienal ligament . Their afferents are derived from the stomach , spleen , and pancreas , their efferents join the celiac group of preaortic glands . Additional images gallery Image illu lymph chain08.jpg Visceral nodes of the abdominal cavity gallery Gray s Lymphatics of torso DEFAULTSORT Splenic Lymph Nodes Category Lymphatics of the torso lymphatic stub ... more details
Blunt splenic trauma occurs when a significant impact to the spleen from some outside source i.e. automobile accident damages or splenic rupture ruptures the spleen . Treatment varies depending on severity, but often consists of embolism or splenectomy . ref name Merck cite book last1 Beers first1 Mark last2 Porter first2 Robert last3 Jones first3 Thomas title The Merck Manual of Diagnosis and Therapy edition 18th year 2006 publisher Merck Research Laboratories location New Jersey chapter 11 isbn 0911910182 ref Cause Blunt splenic trauma most often occurs in automobile accident victims, in which it is a leading cause of internal bleeding. However, any type of major impact directed to the spleen may cause splenic trauma. This can happen in bicycling accidents, when the handlebar is forced into the left subcostal margin, and into the spleen. The degree of injury ranges from subcapsular hematoma, to splenic rupture . ref name Merck Medical Concerns The primary concern in any splenic trauma is internal hemorrhage , though the exact amount of hemorrhage may be small or large, depending on the nature and degree of injury. Small or minor injuries often heal spontaneously, especially in children. Larger injuries hemorrhage extensively, often causing hemorrhagic shock. A splenic hematoma sometimes ruptures, usually in the first few days, although rupture can occur from hours to even months after injury. ref name Merck Signs and Symptoms The primary symptom, hemorrhage, presents differently depending on the degree of injury, with the symptoms of major hemorrhage, shock, abdominal pain ... the need for intervention surgery or embolization in patients with splenic injury. The criteria were established using 20 CT scans from a database of hemodynamically stable patients with blunt splenic ... after splenic injury journal The Journal of trauma volume 60 issue 5 pages 1083 6 year ... involving 50 or more of the splenic parenchyma Contrast blush greater than one centimeter in diameter ... more details
Infobox Artery Name PAGENAME Latin rami pancreatici arteriae splenicae GraySubject GrayPage Image Gray533.png Caption Branches of the celiac artery. Image2 Caption2 BranchFrom splenic artery BranchTo Vein Supplies MeshName MeshNumber DorlandsPre r 02 DorlandsSuf 12691397 The pancreatic branches are numerous small vessels derived from the splenic artery as it runs behind the upper border of the pancreas , supplying its body and tail. One of these, larger than the rest, is sometimes given off near the tail of the pancreas it runs from left to right near the posterior surface of the gland, following the course of the pancreatic duct, and is called the arteria pancreatica magna . These vessels anastomose with the pancreatic branches of the pancreaticoduodenal and superior mesenteric arteries. External links SUNYAnatomyLabs 38 05 01 02 NormanAnatomy pancreas NormanAnatomyFig pancreasvessels Gray s circulatory stub Arteries of thorax and abdomen Category Arteries of the abdomen ... more details
Infobox Disease Name Lymphatic disease Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D008206 Lymphatic disease is a class of disorders which directly affect the components of the lymphatic system . Examples include Castleman s disease ref name urlMedlinePlus Lymphatic Diseases cite web url http www.nlm.nih.gov medlineplus lymphaticdiseases.html cat42 title MedlinePlus Lymphatic Diseases format work accessdate ref and lymphedema . ref name urlLymphedema Lymphatic Disorders Merck Manual Home Edition cite web url http www.merckmanuals.com home heart and blood vessel disorders lymphatic disorders lymphedema.html title Lymphedema Lymphatic Disorders Merck Manual Home Edition format work accessdate ref References reflist Lymphatic diseaseSplenicdisease Thymus disorders Category Lymphatic system Lymphatic stub ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D006402 Hematologic diseases are disorders which primarily affect the blood. Myeloid Hemoglobinopathy Hemoglobinopathies congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis Sickle cell disease Thalassemia Methemoglobinemia Anemia s lack of red blood cells or hemoglobin Iron deficiency anemia Megaloblastic anemia Vitamin B12 Vitamin B small sub 12 sub small deficiency Pernicious anemia Folate deficiency Hemolytic anemias destruction of red blood cells Genetic disorders of RBC membrane Hereditary spherocytosis Hereditary elliptocytosis Congenital dyserythropoietic anemia Genetic disorders of RBC metabolism Glucose 6 phosphate dehydrogenase deficiency G6PD Pyruvate kinase deficiency Immune mediated hemolytic anemia Coombs test Direct Coombs test direct Coombs test is positive Autoimmune hemolytic anemia Warm antibody autoimmune hemolytic ... antibodies Cold agglutinin disease Cold antibody autoimmune hemolytic anemia Idiopathic cold ... anemia Hemolytic disease of the newborn HDN Rh disease Rh D ABO hemolytic disease of the newborn Anti Kell hemolytic disease of the newborn Rhesus c hemolytic disease of the newborn Hemolytic disease of the newborn anti RhE Rhesus E hemolytic disease of the newborn Other blood group incompatibility ... Hemophilia Hemophilia A Hemophilia B also known as Christmas disease Hemophilia C Von Willebrand disease ... Hematological malignancies Lymphoma s Hodgkin s disease Non Hodgkin s lymphoma includes the next eight entries Burkitt s lymphoma Anaplastic large cell lymphoma Splenic marginal zone lymphoma ... disease Monoclonal gammopathy of undetermined significance Hemophagocytic lymphohistiocytosis Hematological changes secondary to non hematological disorders Anemia of chronic disease Infectious mononucleosis ... Diseases of RBCs and megakaryocytes Monocyte and granulocyte disease Certain conditions originating ... more details
Infobox Disease Name Pancreatic disease Image Caption DiseasesDB ICD10 ICD10 K 85 k 80 ICD10 K 86 k 80 , ICD10 Q 45 0 q 38 ICD10 Q 45 3 q 38 ICD9 ICD9 577 , ICD9 751.7 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D010182 Pancreatic diseases include Pancreatitis Pancreatitis is inflammation of the pancreas. There are two forms of pancreatitis, which are different in causes and symptoms, and require different treatment Acute pancreatitis is a rapid onset inflammation of the pancreas, most frequently caused by alcoholism or gallstone s. Chronic pancreatitis is a long standing inflammation of the pancreas. Diabetes mellitus The pancreas is central in the pathophysiology of both major types of diabetes mellitus . In type 1 diabetes mellitus , there is direct damage to the endocrine pancreas that results in insufficient insulin synthesis and secretion. Type 2 diabetes mellitus , which begins with insulin resistance , is characterized by the ultimate failure of pancreatic cells to match insulin production with insulin demand. Exocrine pancreatic insufficiency Exocrine pancreatic insufficiency EPI is the inability to properly digest food due to a lack of digestive enzyme s made by the pancreas. EPI is found in humans afflicted with cystic fibrosis and Shwachman Diamond syndrome. It is caused by a progressive loss of the pancreatic cells that make digestive enzymes. Chronic ... , is a hereditary disease that affects the entire body, causing progressive disability and early death ... disease, 73 patients 2.6 had cysts in the pancreas. ref cite journal author Laffan T, Horton ... adjacent to the pancreas, such as the splenic artery , that bleed into the pancreatic duct. Patients ... with pancreatitis , pancreatic cancer and aneurysm s of the splenic artery . Angiography may ... of digestive system Endocrine pathology DEFAULTSORT Pancreatic Disease Category Pancreas disorders Category Deaths from pancreatic disease hi ... more details
Infobox disease Name Gaucher s disease Image Acid beta glucosidase.png Caption Acid beta glucosidase ... 709 MeshID D005776 GeneReviewsID gaucher GeneReviewsName Gaucher Disease Gaucher s disease IPAc en icon o e z is a genetic disease in which a fatty substance lipid accumulates in cells and certain organs. Gaucher s disease is the most common of the lysosomal storage disease s. ref name Andrews .... Some forms of Gaucher s disease may be treated with enzyme replacement therapy. The disease is caused ... s of the most common type of Gaucher disease, while the carrier rate among Ashkenazi Jews is 8.9 ... GA, Beutler E title High frequency of the Gaucher disease mutation at nucleotide 1226 among ... 1683177 ref The disease is eponym named after the French doctor Philippe Gaucher , who originally described it in 1882. ref name Gaucher1882 Classification Gaucher s disease has three common clinical subtypes. Type I or non neuropathic type is the most common form of the disease, occurring in approximately ... additional complications. Skeletal weakness and bone disease may be extensive. Spleen enlargement ... blood cells. Depending on disease onset and severity, type 1 patients may live well into adulthood. Many patients have a mild form of the disease or may not show any symptoms. Type II or acute infantile neuropathic Gaucher s disease typically begins within 6 months of birth and has an incidence rate ... variations which considerably increase the complexity of predicting disease course. Signs and symptoms ... of splenic rupture. Hypersplenism and pancytopenia the rapid and premature destruction of blood cells ... . Yellowish brown skin pigmentation Pathophysiology The disease is caused by a defect in housekeeping ... mutations carry about a fivefold risk of developing Parkinson s disease , making this the most common known genetic risk factor for Parkinson s. ref cite journal title ASHG 2008 Gaucher Disease Mutation Carriers at Higher Risk for Parkinson s Disease author Jacquelyn K Beals work Medscape Medical ... more details
wiktionary disease A disease is an abnormal condition of an organism that impairs bodily functions and can be deadly. Disease may also refer to Disease album Disease album , a 1993 album by G.G.F.H. Disease song Disease song , a 2002 song by Matchbox Twenty disambiguation ... more details
A polycystic disease is a disease that involves multiple cysts scattered throughout an organ, including Polycystic kidney disease Polycystic liver disease Polycystic ovary syndrome disambig ... more details
Artery disease may refer to the following coronary artery disease Peripheral artery disease, more commonly called peripheral vascular disease Carotid artery disease, more commonly called carotid artery stenosis disambig ... more details
Disease management may refer to Disease management agriculture Disease management health disambig Long comment to avoid being listed on short pages ... more details
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