Taxobox Color parameter is not needed automatically assigned name Spumavirus virus group vi familia Retroviridae subfamilia Spumaretrovirinae genus Spumavirus type species Simian foamy virus subdivision ranks Species subdivision African green monkey simian foamy virus br Macaque simian foamy virus br Bovine foamy virus br Equine foamy virus br Feline foamy virus A spumavirus spuma , Latin for foam or foamyvirus is a genus of the retroviridae family biology family . Spumaviruses are exogenous viruses that have specific morphology biology morphology with prominent surface peplomer spikes . The virions contain significant amounts of double stranded full length DNA , and assembly is rather unusual in these viruses. Supumaviruses are unlike most enveloped viruses in that the viral envelope envelope membrane is acquired by budding through the endoplasmic reticulum instead of the cytoplasmic membrane . Some spumaviruses, including the equine foamy virus EFV , bud from the cytoplasmic membrane. Some examples of this virus are the chimpanzee foamy virus, simian foamy virus and the human foamy virus . While spumaviruses will form characteristic large vacuoles in their host cells while in vitro , there is no disease association in vivo . ref name Acheson cite book author Acheson, NH title Fundamentals of Molecular Virology edition 1st ed. publisher John Wiley & Sons year 2007 isbn 0 471 35151 2 ref References reflist Further reading Santillana Hayat M, Valla J et al. Inhibition of the in vitro infectivity and cytopathic effect of human foamy virus by dideoxynucleosides . AIDS Res Hum Retroviruses. 1996 Oct 10 12 15 1485 90. External links http www.ncbi.nlm.nih.gov books bv.fcgi?rid rv.section.7999 NCBI Spumavirus MeshName Spumavirus http www.expasy.org viralzone all by species 10.html Viralzone Spumavirus Retroviruses Category Spumaviruses virus stub de Spumaviren es Spumavirus ... more details
Taxobox Color parameter is not needed automatically assigned name Simian foamy virus virus group vi familia Retroviridae subfamilia Spumaretrovirinae genus Spumavirus species Simian foamy virus The simian foamy virus SFV is a spumavirus closely related to the Human Immunodeficiency Virus, HIV , the virus that can lead to AIDS . Its discovery in primates has led to some speculation that HIV may have been spread to the human species in Africa through contact with blood from apes , monkeys , and through hunting bushmeat . About 70 90 of non human primates born in captivity have SFV. Animals with SFV do not display symptoms or become ill. However, recent research suggests that some primates that contract SFV would become pre disposed to other viruses. People who have had contact with non human primates can become infected with SFV. ref name pmid15043960 cite journal author Wolfe ND, Switzer WM, Carr JK, et al title Naturally acquired simian retrovirus infections in central African hunters journal Lancet volume 363 issue 9413 pages 932 7 year 2004 month March pmid 15043960 doi 10.1016 S0140 6736 04 15787 5 url ref Description Although the simian foamy virus is Endemic epidemiology endemic in African apes and monkeys, there is not enough evidence that it causes any harm to the population. Its ability to cross over to humans was proven in 2004 by a joint United States and Cameroon ian team which found the retrovirus in gorillas , mandrill s and guenon s unexpectedly they also found it in 10 of 1,100 local Cameroon residents. Of those found infected the majority are males who had been bitten by a non human primate. While this only accounts for 1 of the population, this detail is alarming to some groups Who date September 2007 that fear the outbreak of another AIDS like epidemic . SFV causes Cell biology cell s to fuse with each other to form so called syncytium syncytia , or more figurative, giant cells and look, on a slide, like foamy bubbles, hence its name. It has been t ... more details
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