methyl br tetrahydrofuran 3 carbaldehyde image Streptomycin3.svg width 209 image2 Streptomycin 1ntb xtal 3D balls.png Clinical data Drugs.com drugs.com monograph streptomycin sulfate pregnancy category DM ref name dsafepreg cite web url http drugsafetysite.com streptomycin author year 2006 title Taking Streptomycin during pregnancy and breastfeeding accessdate 2010 05 25 publisher Drug Safety Site ... 2001 title Population pharmacokinetics of intravenous and intramuscular streptomycin in patients with tuberculosis ... stdinchicite correct chemspider StdInChIKey UCSJYZPVAKXKNQ HZYVHMACSA N melting point 12 Streptomycin ... Streptomyces griseus . Streptomycin is a bactericidal antibiotic. ref name Singh1954 cite journal author Singh B, Mitchison DA date 16 January 1954 title Bactericidal Activity of Streptomycin ... 132 pmc 2084433 pmid 13106497 doi 10.1136 bmj.1.4854.130 ref Streptomycin cannot be given orally, but must ... Streptomycin is a protein synthesis inhibitor . It binds to the small 16S rRNA of the 30S subunit .... However at low concentrations Streptomycin only inhibits growth of the bacteria by inducing ... ISBN reason Check digit X does not correspond to calculated figure. ref Streptomycin is an antibiotic ... Streptomycin was first isolated on October 19, 1943 by Albert Schatz scientist Albert Schatz , a graduate ... author Comroe JH Jr title Pay dirt the story of streptomycin. Part I from Waksman to Waksman journal ... , streptomycin, grisein , neomycin , fradicin , candicidin and candidin . Of these, streptomycin .... Streptomycin was the first antibiotic that could be used to cure the disease tuberculosis early ... of streptomycin against pulmonary tuberculosis was carried out in 1946 1947 by the MRC Tuberculosis ... for this purpose by the U.S. Food and Drug Administration . In veterinary medicine , streptomycin .... While streptomycin is traditionally given intramuscular injection intramuscular ly indeed, in many ... injection intravenous ly. ref name Zhu2001 Pesticide Streptomycin is also used as a pesticide ... more details
enzyme Name streptomycin 6 kinase EC number 2.7.1.72 CAS number 37278 11 8 IUBMB EC number 2 7 1 72 GO code 0050300 image width caption In enzymology , a streptomycin 6 kinase EC number 2.7.1.72 is an enzyme that catalysis catalyzes the chemical reaction ATP streptomycin math rightleftharpoons math ADP streptomycin 6 phosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and streptomycin , whereas its two product chemistry products are adenosine diphosphate ADP and streptomycin 6 phosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP streptomycin 6 phosphotransferase . Other names in common use include streptidine kinase , SM 6 kinase , streptomycin 6 kinase phosphorylating , streptidine kinase phosphorylating , streptomycin 6 O phosphotransferase , and streptomycin 6 phosphotransferase . This enzyme participates in streptomycin biosynthesis . References reflist 1 cite journal author Walker JB, Skorvaga M date 1973 title Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives journal J. Biol. Chem. volume 248 pages 2435&ndash 40 pmid 4121456 issue 7 cite journal author Walker JB, Walker MS date 1967 title Streptomycin biosynthesis. Enzymatic synthesis of O phosphorylstreptidine from streptidine and adenosinetriphosphate journal Biochim. Biophys. Acta. volume 148 pages 335&ndash 41 pmid 6075410 issue 2 enzyme stub Category EC 2.7.1 Category Enzymes of unknown structure ... more details
enzyme Name streptomycin 3 adenylyltransferase EC number 2.7.7.47 CAS number 52660 23 8 IUBMB EC number 2 7 7 47 GO code 0009012 image width caption In enzymology , a streptomycin 3 adenylyltransferase EC number 2.7.7.47 is an enzyme that catalysis catalyzes the chemical reaction ATP streptomycin math rightleftharpoons math diphosphate 3 adenylylstreptomycin Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and streptomycin , whereas its two product chemistry products are diphosphate and 3 adenylylstreptomycin . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing nucleotide groups nucleotidyltransferase s . The systematic name of this enzyme class is ATP streptomycin 3 adenylyltransferase . Other names in common use include streptomycin adenylate synthetase , streptomycin adenyltransferase , streptomycin adenylylase , streptomycin adenylyltransferase , streptomycin spectinomycin adenylyltransferase , AAD 3 , and aminoglycoside 3 adenylyltransferase . References reflist 1 cite journal author Harwood JH, Smith DH date 1969 title Resistance factor mediated streptomycin resistance journal J. Bacteriol. volume 97 pages 1262&ndash 71 pmid 4887506 issue 3 pmc 249843 enzyme stub Category EC 2.7.7 Category Enzymes of unknown structure ... more details
enzyme Name streptomycin 3 kinase EC number 2.7.1.87 CAS number 39391 15 6 IUBMB EC number 2 7 1 87 GO code 0050299 image width caption In enzymology , a streptomycin 3 kinase EC number 2.7.1.87 is an enzyme that catalysis catalyzes the chemical reaction ATP streptomycin math rightleftharpoons math ADP streptomycin 3 phosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and streptomycin , whereas its two product chemistry products are adenosine diphosphate ADP and streptomycin 3 phosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP streptomycin 3 phosphotransferase . Other names in common use include streptomycin 3 kinase phosphorylating , and streptomycin 3 phosphotransferase . References reflist 1 cite journal author Walker JB, Skorvaga M year 1973 title Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives journal J. Biol. Chem. volume 248 pages 2435&ndash 40 pmid 4121456 issue 7 Category EC 2.7.1 Category Enzymes of unknown structure enzyme stub ... more details
enzyme Name streptomycin 6 phosphatase EC number 3.1.3.39 CAS number 9055 33 8 IUBMB EC number 3 1 3 39 GO code 0050301 image width caption In enzymology , a streptomycin 6 phosphatase EC number 3.1.3.39 is an enzyme that catalysis catalyzes the chemical reaction streptomycin 6 phosphate H sub 2 sub O math rightleftharpoons math streptomycin phosphate Thus, the two substrate biochemistry substrates of this enzyme are streptomycin 6 phosphate and water H sub 2 sub O , whereas its two product chemistry products are streptomycin and phosphate . This enzyme belongs to the family of hydrolase s, specifically those acting on phosphoric ester monoester bonds. The systematic name of this enzyme class is streptomycin 6 phosphate phosphohydrolase . Other names in common use include streptomycin 6 phosphate phosphatase , streptomycin 6 phosphate phosphohydrolase , and streptomycin 6 P phosphohydrolase . This enzyme participates in streptomycin biosynthesis . References reflist 1 cite journal author Walker JB, Skorvaga M date 1973 title Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6 phosphate to inosamines, streptamine, and 2 deoxystreptamine journal J. Biol. Chem. volume 248 pages 2441&ndash 6 pmid 4121457 issue 7 cite journal author Walker MS, Walker JB date 1971 title Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy scyllo inositol phosphate and streptomycin streptidino phosphate journal J. Biol. Chem. volume 246 pages 7034&ndash 40 pmid 4331203 issue 22 hydrolase stub Category EC 3.1.3 Category Enzymes of unknown structure ... more details
Image Streptomycin structure.png thumb 120px right Streptomycin , an important antibiotic drug produced by Streptomyces bacteria Secondary metabolism also called special metabolism is a term for pathways and small molecule products of metabolism that are not absolutely required for the survival of the organism . Examples of the products include antibiotics and pigment s. To distinguish non secondary ordinary metabolism, the term basic metabolism is sometimes used. Secondary metabolite s are produced by microbe s, plants, fungi and animals, but not by all of them. Important secondary metabolites main Secondary metabolite Antibiotic s, such as streptomycin and penicillin Pigment s, such as delphinidin References Unreferenced date June 2008 External links http www.biologie.uni hamburg.de b online e20 20.htm Secondary metabolism in plants Category Metabolism biochemistry stub fi Sekundaarimetabolia es Metabolito secundario ... more details
Albert Schatz may refer to Albert Schatz law 1879 ? , law professor and historian Albert Gerard Schatz 1921 1985 , U.S. federal judge Albert Schatz music 1839 1910 , musicologist, composer, and librettist Albert Schatz scientist 1922 2005 , microbiologist, co discoverer of streptomycin hndis name Schatz, Albert bg fr Albert Schatz ... more details
Unreferenced type bacteria auto yes date December 2009 Taxobox image Streptomyces sp 01.png image width 240px image caption Slide culture of a Streptomyces species regnum Bacteria phylum Actinobacteria classis Actinobacteria ordo Actinomycetales subordo Streptomycineae subordo authority Rainey et al. 1997 familia Streptomycetaceae familia authority Waksman & Henrici 1943 subdivision ranks Genera Verify source date July 2010 only these two? Streptoverticillium here included in Streptomyces subdivision Kitasatospora br Streptomyces br Streptoverticillium Streptomycetaceae is a family biology family of Actinobacteria , making up to the monotypic suborder Streptomycineae . It includes the important genus Streptomyces . This was the original source of many antibiotics , namely streptomycin . Streptomycin was the first antibiotic against tuberculosis . References reflist External links wikispecies Category Streptomycineae Bacteria stub es Streptomycetaceae nl Streptomycetaceae ... more details
Image Waksman sign.jpg thumb right 300px Sign at the side entrance of the Waksman Institute The Waksman Institute of Microbiology is a research facility on the Busch Campus Rutgers University Busch Campus of Rutgers University . It is named after Selman Waksman , who was a faculty member who won the Nobel Prize for Medicine in 1952 for research which led to the discovery of streptomycin . 18 antibiotics were isolated in Waksman s laboratory. Streptomycin and neomycin , and actinomycin , were commercialized. The current director of the Institute is Professor Joachim Messing . References New York Times Thursday, May 23, 1974 Waksman Institute Marks Two Decades of Research Royalties Running Out. A group of scientists who hope to help solve some of the world s biggest problems through control of its smallest living organisms celebrated the 20th anniversary of their combined effort this week. Rutgers Category Rutgers University ... more details
enzyme Name guanidinodeoxy scyllo inositol 4 phosphatase EC number 3.1.3.40 CAS number 9055 28 1 IUBMB EC number 3 1 3 40 GO code 0047383 image width caption In enzymology , a guanidinodeoxy scyllo inositol 4 phosphatase EC number 3.1.3.40 is an enzyme that catalysis catalyzes the chemical reaction 1 guanidino 1 deoxy scyllo inositol 4 phosphate H sub 2 sub O math rightleftharpoons math 1 guanidino 1 deoxy scyllo inositol phosphate Thus, the two substrate biochemistry substrates of this enzyme are 1 guanidino 1 deoxy scyllo inositol 4 phosphate and water H sub 2 sub O , whereas its two product chemistry products are 1 guanidino 1 deoxy scyllo inositol and phosphate . This enzyme belongs to the family of hydrolase s, specifically those acting on phosphoric ester monoester bonds. The systematic name of this enzyme class is 1 guanidino 1 deoxy scyllo inositol 4 phosphate 4 phosphohydrolase . Other names in common use include 1 guanidino scyllo inositol 4 phosphatase , and 1 guanidino 1 deoxy scyllo inositol 4 P phosphohydrolase . References reflist 1 cite journal author Walker MS, Walker JB date 1971 title Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy scyllo inositol phosphate and streptomycin streptidino phosphate journal J. Biol. Chem. volume 246 pages 7034&ndash 40 pmid 4331203 issue 22 Category EC 3.1.3 Category Enzymes of unknown structure hydrolase stub ... more details
Drugbox verifiedrevid 408380133 Combo data type combo component1 Streptomycin class1 Aminoglycoside antibiotic component2 Dihydrostreptomycin class2 Aminoglycoside antibiotic Clinical data tradename pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Identifiers CAS number ATC prefix J01 ATC suffix GA02 PubChem 202223 DrugBank Ref drugbankcite correct drugbank DrugBank Chemical data Streptoduocin is an aminoglycoside antibiotic . It is a mixture of streptomycin and dihydrostreptomycin . ref name pmid13261867 cite journal author SHUBIN H, HEIKEN CA, GLASKIN A, PENNES E, CHAKRAVARTY S, RUTBERG F title A study of the neurotoxicity of streptoduocin on tuberculous patients journal Dis Chest volume 28 issue 4 pages 447 50 year 1955 pmid 13261867 doi url http www.chestjournal.org cgi content abstract 28 4 447 ref References reflist AminoglycosideAntiBiotics Category Aminoglycoside antibiotics Category Combination antibiotics antibiotic stub ... more details
of Streptomycin , and several other antibiotic s. A professor of biochemistry and microbiology ... in recognition for his discovery of streptomycin, the first antibiotic active against tuberculosis ... more than fifteen antibiotics, including streptomycin, which was the first effective treatment for tuberculosis ... several antibiotics, including actinomycin , clavacin , streptothricin , streptomycin , grisein , neomycin , fradicin , candicidin , candidin , and others. Two of these, streptomycin and neomycin , have found extensive application in the treatment of numerous infectious diseases. Streptomycin was the first ... root stock to protect the French Vineyards from fungal infection. Streptomycin main streptomycin Waksman ..., been studying the organism Streptomyces griseus . Streptomycin was isolated from S. griseus ... Jack ref Controversy The details and credit for the discovery of streptomycin and its usefulness ... in financial remuneration and entitlement to legal and scientific credit as co discoverer of streptomycin ... healer. url http www.guardian.co.uk weekend story 0,3605,823114,00.html quote The story of streptomycin ... Waksman was awarded the Nobel Prize in 1952 for for his discovery of streptomycin, the first antibiotic ... for the discovery of streptomycin but also for the development of the methods and techniques that led ... and allied sciences v059 59.3kingston.html Streptomycin, Schatz v. Waksman, and the Balance ... scientist, biochemist, microbiologist who discovered Streptomycin and many antibiotics. DATE ... more details
of streptomycin was credited only to Schatz s supervisor, Selman Waksman . ref name young ref .... Streptomycin Discovery and War over Nobel Prize With a meager stipend, Schatz lived in a small ... at Cook College in Rutgers University. Dr Waksman was at the last stages of purifying streptomycin ... paper, and had soon after the discovery issued his doctorate thesis on the discovery of streptomycin. citation needed date November 2011 Career Originally, the discovery of streptomycin was credited ..., requesting recognition as streptomycin s co discoverer and a portion of streptomycin royalties ... in 1980. Schatz was awarded the Rutgers medal in 1994 for his work on developing streptomycin. In the 1990s ... albert schatz 485352.html Albert Schatz Co discoverer of streptomycin . The Independent. ref which was criticized ... www.ingeauerbacher.com books.htm Finding 20Dr. 20Schatz Finding Dr. Schatz The Discovery of Streptomycin and a Life It Saved with Schatz. The book chronicled his discovery of streptomycin and meeting ... of streptomycin, dies at 84 1504 Rutgers Focus obituary http muse.jhu.edu journals journal of the history of medicine and allied sciences v059 59.3kingston.html Streptomycin, Schatz v. Waksman ... containing scanned newspaper clippings from the time of the discovery of Streptomycin References ... more details
enzyme Name scyllo inosamine 4 phosphate amidinotransferase EC number 2.1.4.2 CAS number 52227 63 1 IUBMB EC number 2 1 4 2 GO code 0015069 image width caption Orphan date February 2009 In enzymology , a scyllo inosamine 4 phosphate amidinotransferase EC number 2.1.4.2 is an enzyme that catalysis catalyzes the chemical reaction L arginine 1 amino 1 deoxy scyllo inositol 4 phosphate math rightleftharpoons math L ornithine 1 guanidino 1 deoxy scyllo inositol 4 phosphate Thus, the two substrate biochemistry substrates of this enzyme are L arginine and 1 amino 1 deoxy scyllo inositol 4 phosphate , whereas its two product chemistry products are L ornithine and 1 guanidino 1 deoxy scyllo inositol 4 phosphate . This enzyme belongs to the family of transferase s that transfer one carbon groups, specifically the amidinotransferases. The systematic name of this enzyme class is L arginine 1 amino 1 deoxy scyllo inositol 4 phosphate amidinotransferase . Other names in common use include L arginine inosamine P amidinotransferase , inosamine P amidinotransferase , L arginine inosamine phosphate amidinotransferase , and inosamine phosphate amidinotransferase . This enzyme participates in streptomycin biosynthesis . Structural studies As of late 2007, only one tertiary structure structure has been solved for this class of enzymes, with the Protein Data Bank PDB accession code PDB link 1BWD . References reflist 1 cite journal author Walker MS and Walker JB date 1966 title Enzymic studies on the biosynthesis of streptomycin, transamidation of inosamine and streptamine derivatives journal J. Biol. Chem. volume 241 pages 1262&ndash 1269 transferase stub Category EC 2.1.4 Category Enzymes of known structure it Scillo inosammina 4 fosfato amidinotransferasi ... more details
enzyme Name 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol transaminase EC number 2.6.1.56 CAS number 57127 19 2 IUBMB EC number 2 6 1 56 GO code 0047311 image width caption In enzymology , a 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol transaminase EC number 2.6.1.56 is an enzyme that catalysis catalyzes the chemical reaction 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol pyruvate math rightleftharpoons math 1D 1 guanidino 1 deoxy 3 dehydro scyllo inositol L alanine Thus, the two substrate biochemistry substrates of this enzyme are 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol and pyruvate , whereas its two product chemistry products are 1D 1 guanidino 1 deoxy 3 dehydro scyllo inositol and L alanine . This enzyme belongs to the family of transferase s, specifically the transaminases , which transfer nitrogenous groups. The systematic name of this enzyme class is 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol pyruvate aminotransferase . Other names in common use include guanidinoaminodideoxy scyllo inositol pyruvate aminotransferase , and L alanine N amidino 3 or 5 keto scyllo inosamine transaminase . References reflist 1 cite journal author Walker JB date 1971 title Enzymatic reactions involved in streptomycin biosynthesis and metabolism journal Lloydia. volume 34 pages 363&ndash 71 pmid 4376579 issue 4 cite journal author Walker JB, Walker MS date 1969 title Streptomycin biosynthesis. Transamination reactions involving inosamines and inosadiamines journal Biochemistry. volume 8 pages 763&ndash 70 pmid 5781017 doi 10.1021 bi00831a003 issue 3 transferase stub Category EC 2.6.1 Category Enzymes of unknown structure ... more details
enzyme Name scyllo inosamine 4 kinase EC number 2.7.1.65 CAS number 37278 08 3 IUBMB EC number 2 7 1 65 GO code 0050276 image width caption In enzymology , a scyllo inosamine 4 kinase EC number 2.7.1.65 is an enzyme that catalysis catalyzes the chemical reaction ATP 1 amino 1 deoxy scyllo inositol math rightleftharpoons math ADP 1 amino 1 deoxy scyllo inositol 4 phosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and 1 amino 1 deoxy scyllo inositol , whereas its two product chemistry products are adenosine diphosphate ADP and 1 amino 1 deoxy scyllo inositol 4 phosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP 1 amino 1 deoxy scyllo inositol 4 phosphotransferase . Other names in common use include scyllo inosamine kinase phosphorylating , scyllo inosamine kinase , and ATP inosamine phosphotransferase . This enzyme participates in streptomycin biosynthesis . References reflist 1 cite journal author Walker JB date 1971 title Enzymatic reactions involved in streptomycin biosynthesis and metabolism journal Lloydia. volume 34 pages 363&ndash 71 pmid 4376579 issue 4 cite journal author Walker JB, Walker MS date 1967 title Enzymatic synthesis of streptidine from scyllo inosamine journal Biochemistry. volume 6 pages 3821&ndash 9 pmid 6076630 doi 10.1021 bi00864a028 issue 12 enzyme stub Category EC 2.7.1 Category Enzymes of unknown structure ... more details
Philip Montagu D Arcy Hart , CBE , 25 June 1900 30 July 2006 was a British medical researcher and pioneer in tuberculosis treatment. Grandson of Samuel Montagu, 1st Baron Swaythling , he became a consultant physician at University College Hospital at the age of 34. Three years later, he joined the Medical Research Council MRC , and became involved with much of the MRC s early research into dust diseases in coal miners. He was a member of the MRC Streptomycin in Tuberculosis Trials Committee their study evaluating the use of streptomycin in treating tuberculosis is generally accepted as the first randomized clinical trial. At the age of 71, Hart published a seminal paper in the Journal of Experimental Medicine , showing the intracellular pathogen Mycobacterium tuberculosis avoids destruction in the cell s lysosomes by circumventing these organelles altogether a trick now known to be used by many other intracellular pathogens. In 1941, Hart married Ruth Meyer, later a medical gynaecologist. They had a son, Oliver Hart economist Oliver Hart . Philip D Arcy Hart died at the age of 106 in 2006. ref cite web url http www.genarians.com In 20Memoriam 202006.html title Noted Nonagenarians & Centenarians In Memoriam 2006 publisher generians.com ref References Reflist Persondata Metadata see Wikipedia Persondata . NAME Darcy Hart, Philip ALTERNATIVE NAMES SHORT DESCRIPTION PLACE OF BIRTH PLACE OF DEATH date of birth 1900 date of death 2006 DATE OF BIRTH 25 June 1900 DATE OF DEATH 30 July 2006 DEFAULTSORT Hart, Philip Darcy Category Epidemiologists Category 20th century English medical doctors Category English centenarians Category English Jews Category Old Cliftonians Category Tuberculosis Category 1900 births Category 2006 deaths UK med bio stub ... more details
File J558L Mouse B Myeloma Cell Line.jpg thumb J558L Mouse B Myeloma Cell Line J558L cells are mouse B myeloma cells derived from BALB c strain isolated by M. Bruggeman and M.S. Neuberger in University of Cambridge ref http www.ncbi.nlm.nih.gov pubmed 6402777?dopt Abstract ref ref http www.hpacultures.org.uk products celllines generalcell detail.jsp?refId 88032902&collection ecacc gc ref . It is a stable B cell line used to express antibodies. They are a suspension cell line and are best cultured in DMEM Eagle s minimal essential medium with 10 Fetal bovine serum , 0.01 units ml of penicillin and 0.1 mg ml streptomycin incubated in 37 C 5 CO sub 2 sub 90 relative humidity with a cell density of 5x10 sup 5 sup cell per 15 ml. Uses This cell line is usually used to express antibodies since they can result in antibody titers up to 1mg under optimum conditions. References reflist Category Cell lines ... more details
Dablink For one of the several German U boats sometimes referred to as U87 , see German submarine U 87 German submarine U 87 Refimprove date December 2009 In cell biology , U87 is a human primary glioblastoma cell line formally known as U 87 MG. It has epithelial morphology biology morphology , and was obtained from a stage four cancer patient ref cite journal pmid PMC2813426 url http www.ncbi.nlm.nih.gov pmc articles PMC2813426 ?tool pubmed ref . U 87 MG can be obtained from the American Type Culture Collection ATCC where it is known by the accession number HTB 14. The entire sequence of the genome of U 87 MG has recently been published in PLoS Genetics, 2010 January 6 1 e1000832. Growth conditions U87 growth media is generally made with Eagle s minimum essential medium 10 FBS 100 U ml penicillin 100 ug ml streptomycin. ref cite web title HTB 14 url http www.atcc.org ATCCAdvancedCatalogSearch ProductDetails tabid 452 Default.aspx?ATCCNum HTB 14&Template cellBiology publisher ATCC ref It is propagated at 37 degrees Celsius in a 5 carbon dioxide atmosphere. References Reflist External links http www.atcc.org ATCCAdvancedCatalogSearch ProductDetails tabid 452 Default.aspx?ATCCNum HTB 14&Template cellBiology ATCC record for HTB 14 http www.ncbi.nlm.nih.gov pmc articles PMC2813426 ?tool pubmed U87MG Decoded The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line Category Cell biology Cell biology stub ... more details
STR , StR , Str or str may stand for Stranraer Harbour railway station Short tandem repeat , in DNA testing Special Theory of Relativity , Einstein s theory String computer science , in computing Steps To Reproduce , in computing, used in bug filing and testing R Tree Sort Tile Recursive an efficient and particularly effective method of bulk loading an R Tree United States Trade Representative , formerly known as a Special Trade Representative Stuttgart Airport , Germany IATA code Scuderia Toro Rosso , a Formula 1 racing team Suspicious Transaction Report, see Currency Transaction Report S minaire Saint Joseph de Trois Rivi res , a school in Quebec Specialized Technology Resources , an American corporation Suspend to RAM , in computing Sociedade da Terra Redonda , a Brazilian atheist and skeptic organization Super Trucks Racing , a video game for the PlayStation 2 An accepted abbreviation for Streptomycin , an antibiotic, in bacterial molecular biology Specialty Registrar StR , a medical specialty title in the UK intended to replace SpR Office of the United States Trade Representative , known as the Office of the Special Trade Representative STR until 1979. disambig cs STR de STR eo STR fr STR ko STR id STR it STR nl STR ja STR pl STR pt STR sv STR ... more details
italic title Context date October 2009 Taxobox name Mycobacterium alvei regnum Bacteria phylum Actinobacteria ordo Actinomycetales subordo Corynebacterineae familia Mycobacterium Mycobacteriaceae genus Mycobacterium species M. alvei binomial Mycobacterium alvei binomial authority Ausina et al. 1992, ATCC 51304 Mycobacterium alvei Description Gram positive , nonmotile and acid fast rods 1 3 m x 0.5 0.7 m . Colony characteristics Colonies are eugonic , rough and nonpigmented. Physiology Colonies occur within 5 days at 30 C optimum temperature, no growth at 45 C on L wenstein Jensen medium and on Middlebrook 7H10 agar. The type strain is resistant to D cycloserine , streptomycin , isoniazid , rifampin , and thiacetazone The type strain is susceptible to kanamycin , capreomycin and high levels of isoniazid . Differential characteristics Differentiation from all other mycobacterial species by its unusual mycolate pattern. Pathogenesis Not associated with disease. Biosafety level 1 Type strain First isolated from water samples, from soil and human sputum samples in Spain. Strain CR 21 ATCC 51304 CIP 103464 DSM 44176 JCM 12272. References reflist Ausina et al. 1992. Mycobacterium alvei sp. nov. Int. J. Syst. Bacteriol., 1992, 42, 529 535. Mycobacteria DEFAULTSORT Mycobacterium Alvei Category Acid fast bacilli Category Corynebacterineae Category Nontuberculous mycobacteria Mycobacterium stub ... more details
italic title Taxobox name Mycobacterium kubicae regnum Bacteria phylum Actinobacteria ordo Actinomycetales subordo Corynebacterineae familia Mycobacterium Mycobacteriaceae genus Mycobacterium species M. kubicae binomial Mycobacterium kubicae binomial authority Floyd et al. 2000, ATCC 700732 Mycobacterium kubicae Description Gram positive , nonmotile and acid fast rods. Cells are typically rod shaped, with some coccoid forms. Colony characteristics Smooth and domed, with a yellow scotochromogenic pigment on Middlebrook 7H11 agar, film like on L wenstein Jensen media. Physiology Mature growth in 21 days between 33 C and 37 C. Isolates are resistant to amikacin and rifampin Partially resistant to ciprofloxacin , cycloserine , ethambutol , isoniazid , rifabutin and streptomycin , Susceptible to clarithromycin , clofazimine and ethionamide . Pathogenicity. Distribution. Pathogenesis Not known to be associated with disease. Biosafety level unknown Type strain The type strain was isolated from human sputum . Strain ATCC 700732 CDC 941078 CIP 106428 DSM 44627 JCM 13573. References reflist Floyd et al. 2000. Mycobacterium kubicae sp. nov., a slowly growing, scotochromogenic Mycobacterium. Int. J. Syst. Evol. Microbiol., 50, 1811 1816. Mycobacteria DEFAULTSORT Mycobacterium Kubicae Category Acid fast bacilli Category Corynebacterineae Category Nontuberculous mycobacteria Mycobacterium stub ... more details
enzyme Name glutamine scyllo inositol transaminase EC number 2.6.1.50 CAS number 9033 03 8 IUBMB EC number 2 6 1 50 GO code 0047310 image width caption In enzymology , a glutamine scyllo inositol transaminase EC number 2.6.1.50 is an enzyme that catalysis catalyzes the chemical reaction L glutamine 2,4,6 3,5 pentahydroxycyclohexanone math rightleftharpoons math 2 oxoglutaramate 1 amino 1 deoxy scyllo inositol Thus, the two substrate biochemistry substrates of this enzyme are L glutamine and 2,4,6 3,5 pentahydroxycyclohexanone , whereas its two product chemistry products are 2 oxoglutaramate and 1 amino 1 deoxy scyllo inositol . This enzyme belongs to the family of transferase s, specifically the transaminases , which transfer nitrogenous groups. The systematic name of this enzyme class is L glutamine 2,4,6 3,5 pentahydroxycyclohexanone aminotransferase . Other names in common use include glutamine scyllo inosose aminotransferase , L glutamine keto scyllo inositol aminotransferase , glutamine scyllo inosose transaminase , and L glutamine scyllo inosose transaminase . It employs one cofactor biochemistry cofactor , pyridoxal phosphate . References reflist 1 cite journal author Walker JB, Walker MS date 1969 title Streptomycin biosynthesis. Transamination reactions involving inosamines and inosadiamines journal Biochemistry. volume 8 pages 763&ndash 70 pmid 5781017 doi 10.1021 bi00831a003 issue 3 transferase stub Category EC 2.6.1 Category Pyridoxal phosphate enzymes Category Enzymes of unknown structure ... more details
enzyme Name dihydrostreptomycin 6 phosphate 3 alpha kinase EC number 2.7.1.88 CAS number 39391 14 5 IUBMB EC number 2 7 1 88 GO code 0047333 image width caption In enzymology , a dihydrostreptomycin 6 phosphate 3 alpha kinase EC number 2.7.1.88 is an enzyme that catalysis catalyzes the chemical reaction ATP dihydrostreptomycin 6 phosphate math rightleftharpoons math ADP dihydrostreptomycin 3 alpha,6 bisphosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and dihydrostreptomycin 6 phosphate , whereas its two product chemistry products are adenosine diphosphate ADP and dihydrostreptomycin 3 alpha,6 bisphosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP dihydrostreptomycin 6 phosphate 3 alpha phosphotransferase . Other names in common use include dihydrostreptomycin 6 phosphate kinase phosphorylating , and ATP dihydrostreptomycin 6 P 3 alpha phosphotransferase . References reflist 1 cite journal author Walker JB, Skorvaga M date 1973 title Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives journal J. Biol. Chem. volume 248 pages 2435&ndash 40 pmid 4121456 issue 7 enzyme stub Category EC 2.7.1 Category Enzymes of unknown structure ... more details
Robert Kilpatrick, Baron Kilpatrick of Kincraig 29 July 1926 is a British politician. Life He is a member of the House of Lords since 1996. There he sits as a crossbencher. Having suffered from tuberculosis when younger and been one of the first patients to be treated with the antibiotic streptomycin , Lord Kilpatrick is now a patron of the charity TB Alert . ref http www.tbalert.org about people.php TB Alert website ref References http biographies.parliament.uk parliament default.asp?id 27003 Parliament.uk references Sources http hansard.millbanksystems.com people mr robert kilpatrick http www.eurosource.eu.com engine.asp?lev1 4&lev2 38&menu 73&biog y&id 27003&group 5&Page Lord 20Kilpatrick 20of 20Kincraig 20 20Political 20Biography Dead link date October 2011 http www.burkes peerage.net familyhomepage.aspx?FID 0&FN KILPATRICKOFKINCRAIG Dead link date October 2011 Persondata Metadata see Wikipedia Persondata . NAME Kilpatrick ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH July 29, 1926 PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Kilpatrick Category Crossbench life peers Category Living people Category 1926 births ... more details
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