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Therapeutic gene modulation





Encyclopedia results for Therapeutic gene modulation

  1. Therapeutic gene modulation

    Unreferenced stub auto yes date December 2009 Therapeutic gene modulation refers the practice of altering the Gene expression expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene perhaps through the introduction of a gene encoding a novel modulatory protein whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly. Modulation of gene expression can be mediated at the level of Transcription genetics transcription by artificial transcription factors or at the level of translation through RNA interference . Clinical significance All cancer is due to cells with misregulated genes, and correcting that regulation might cure the disease. For example, many cancerous cells must upregulate the enzyme telomerase in order to become immortalized. Similarly, high cholesterol levels could be treated by downregulating the genes involved with cholesterol biosynthesis , while any viral infection could be mitigated by downregulating the cell surface receptor the virus uses to gain entry, so long as that receptor is not critical for the cell s survival for example, HIV and the receptor CXCR4 . Of the two methods mentioned above for gene modulation, most clinical research seems to be in RNA interference see RNA interference Medicine . Current obstacles to this approach include its tendency to sometimes modulate other genes with sequence similarity to the target, and a difficulty in transporting exogenous RNA into cells. There are currently no clinically approved therapies using RNAi based therapeutics, although there are a number in clinical trials for example, see http www.silence therapeutics.com content pipeline ... Artificial transcription factor Antisense therapy Gene therapy RNA interference DEFAULTSORT Therapeutic Gene Modulation Category Medical genetics Category Applied genetics Medicine stub ur ...   more details



  1. Modulation

    About musical change of key Modulation music other uses Modulation techniques In electronics and telecommunications , modulation is the process of varying one or more properties of a high frequency periodic ... , modulation is the process of conveying a message signal, for example a digital bit stream or an analog audio signal, inside another signal that can be physically transmitted. Modulation ... of the passband. A device that performs modulation is known as a modulator and a device that performs the inverse operation of modulation is known as a demodulator sometimes detector or demod . A device ... modulation is to transfer a digital bit stream over an analog bandpass Channel communications channel ... modulation is to transfer an analog signal analog baseband or lowpass signal, for example an audio ... modulation facilitate frequency division multiplexing FDM , where several low pass information signals ... several different carrier frequencies . The aim of digital baseband modulation methods, also ... filtered copper wire such as a serial bus or a wired local area network . The aim of pulse modulation ... synthesizers, modulation may be used to synthesise waveforms with an extensive overtone spectrum ... order or much lower than the modulating waveform. See for example frequency modulation synthesis or Ring modulation Use in music ring modulation synthesis . Analog modulation methods File Amfm3 en de.gif ... signal analog modulation, the modulation is applied continuously in response to the analog information signal. Common analog modulation techniques are ref cite book title Analog and Digital ... pages 163 184 url http books.google.com books?id JKfTrRRHT5QC&pg PA164 ref Amplitude modulation AM ... signal Double sideband modulation DSB Double sideband modulation with carrier DSB WC ... sideband reduced carrier transmission DSB RC Single sideband modulation SSB, or SSB AM SSB with carrier SSB WC SSB suppressed carrier modulation SSB SC Vestigial sideband modulation VSB, or VSB AM Quadrature ...   more details



  1. Modulation index

    The modulation index or modulation depth of a modulation scheme describes by how much the modulated variable of the carrier signal varies around its unmodulated level. It is defined differently in each modulation scheme. See amplitude modulation Modulation index Amplitude modulation index frequency modulation Modulation index Frequency modulation index phase modulation Modulation index Phase modulation index Disambig ...   more details



  1. Therapeutic target

    Therapeutic target may refer to Biological target , a protein or nucleic acid whose activity can be modified by an external stimulus Therapeutic Targets Database , a database to provide information about the known and explored therapeutic targets Therapeutic target range , an alternative reference range disambig ...   more details



  1. Angle modulation

    Angle modulation is a class of analog signal analog modulation . These techniques are based on altering the angle or phase waves phase of a sinusoidal carrier wave to Transmission telecommunications transmit data, as opposed to varying the amplitude , such as in Amplitude modulation AM transmission. Angle Modulation is modulation in which the angle of a sine wave carrier is varied by a modulating wave. Frequency Modulation FM and Phase Modulation PM are two types of angle modulation. In frequency modulation the modulating signal causes the carrier frequency to vary. These variations are controlled by both the frequency and the amplitude of the modulating wave. In phase modulation the phase of the carrier is controlled by the modulating waveform. The two main types of angle modulation are Frequency modulation FM , with its digital correspondence frequency shift keying FSK . Phase modulation PM , with its digital correspondence phase shift keying PSK . See also Modulation Polar modulation External links http www.vk1od.net FM FM.htm Discussion of practical implementation of FM PM systems telecom stub Category Radio modulation modes de Winkelmodulation ru su Modulasi sudut ...   more details



  1. Therapeutic privilege

    Orphan date February 2009 A therapeutic privilege or therapeutic exception refers to an uncommon situation whereby a physician may be excused from revealing information to a patient when disclosing it would pose a serious psychological threat, so serious a threat as to be medically contraindicated. ref name virtualmentor.ama assn.org http virtualmentor.ama assn.org 2004 02 msoc1 0402.html ref The therapeutic privilege is an exception to the general rule of informed consent , and only applies when disclosure of the information itself could pose serious and immediate harm to the patient, such as prompting suicidal behaviour. ref cite journal author van den Heever P title Pleading the defence of therapeutic privilege journal S Afr Med J volume 95 issue 6 pages 420 1 year 2005 pmid 16100889 ref The exception of therapeutic privilege does not apply when disclosure will merely lead to refusal of care that the physician thinks beneficial. ref name virtualmentor.ama assn.org References references DEFAULTSORT Therapeutic Privilege Category Medical ethics Category Privileged communication ...   more details



  1. Therapeutic misconception

    Therapeutic misconception is a common ethical problem encountered in human subjects research. It was originally described in 1982 by Paul Appelbaum and his colleagues. The idea was introduced to the bioethics community in 1987 ref cite journal last Kimmelman first Jonathan title The therapeutic misconception at 25 treatment, research, and confusion year 2007 volume 37 issue 6 pages 36 42 ref . The original formulation given by Appelbaum was the following To maintain a therapeutic misconception is to deny the possibility that there may be major disadvantages to participating in clinical research ... Data Consent to Research and the Therapeutic Misconception journal The Hastings Center Report year 1987 volume 27 issue 2 pages 20 24 ref Context and definitions Therapeutic misconception did not receive ..., it is now commonly used among sociologists, neuroscientists, and clinical investigators. Therapeutic ... decision. Certain factors can increase the risk of therapeutic misconception, such as studies ... treatments. Strategies to minimize the possibility of therapeutic misconception may involve giving ... alternatives. Therapeutic misestimation Therapeutic misestimation may occur when subjects ... associated with a particular study. What separates therapeutic misconception from therapeutic misestimation is that in therapeutic misestimation subjects overestimate the benefits of a trial even though ... in clinical research distinguishing therapeutic misconception, therapeutic misestimation, and therapeutic optimism journal IRB year 2003 volume 25 issue 1 pages 11 6 ref . Therapeutic optimism Therapeutic ... distinguishing therapeutic misconception, therapeutic misestimation, and therapeutic optimism journal ... to appreciate the difference between research and treatment, labeling the phenomenon therapeutic misconception . Henderson et al., Clinical Trials and Medical Care Defining the Therapeutic Misconception, 2007 Clinical Trials and Medical Care Defining the Therapeutic Misconception. PLoS Med 4 11 e324 ...   more details



  1. Therapeutic angiogenesis

    Orphan date November 2006 Therapeutic angiogenesis is an experimental area of treatment of ischemia , the condition which associated with decrease in blood supply to certain body organs, tissue or part. This usually caused by constriction or obstruction of the blood vessels. Angiogenesis is the natural healing process by which new blood vessel s are formed to supply the organ or part in deficit with oxygen rich blood. The goal of therapeutic angiogenesis is to stimulate the creation of new blood vessels in ischemic organs, tissues or parts in hope to increase the level of oxygen rich blood reaching these areas. See also Vascular endothelial growth factor References 1. Isner JM. Therapeutic angiogenesis a new frontier for vascular therapy. Vasc Med . 1996 1 79 87. 2. Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature . 2005 Dec 15 438 7070 967 74. 3. Losordo DW, Dimmeler S. Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I angiogenic cytokines. Circulation . 2004 109 2487 2491 4. Cao L, Mooney DJ. Spatiotemporal control over growth factor signaling for therapeutic neovascularization. Adv Drug Deliv Rev. 2007 Nov 10 59 13 1340 50. External links http angio.org understanding information.php Therapeutic Angiogenesis for Tissue Repair and Regeneration from http www.angio.org The Angiogenesis Foundation , 23 June 2009 DEFAULTSORT Therapeutic Angiogenesis Category Vascular procedures treatment stub ...   more details



  1. Therapeutic governance

    orphan date May 2010 Therapeutic governance refers to the management of the populations psychology , and its significance for security . ref Pupavac, Vannessa 1 August 2005 . Human Security and the rise of global therapeutic governance Conflict, Security and Development . Vol. 5. No. 2. pp. 161 181. ref References reflist Category Political philosophy ...   more details



  1. Therapeutic community

    Therapeutic community is a term applied to a participative, group based approach to long term mental ... group psychotherapy as well as practical activities. Therapeutic communities have gained some reputation ..., democratic analytic therapeutic communities have tended to specialise in the treatment of moderate to severe personality disorders and complex emotional and interpersonal problems. The evolution of therapeutic ... UK The term was coined by Thomas Main in his 1946 paper, The hospital as a therapeutic institution , ref name Main cite journal author Main T. title The Hospital as a Therapeutic Institution journal ... II second World War , the concept of the therapeutic community and its attenuated form the therapeutic milieu caught on and dominated the field of inpatient psychiatry throughout the 1960s. The aim of therapeutic communities was a more democratic, user led form of therapeutic environment, avoiding the authoritarian ... has recently been threatened because of changes in funding systems. However, development of mini therapeutic ... support , now offers a more resource and cost effective alternative to traditional inpatient therapeutic ... moderated by service users according to therapeutic community principles. This extends the community beyond the face to face therapeutic days . The website guarantees a safe group based response ... Foundation initiated therapeutic communities in the United States Penitentiary, Marion ... Analysis , the Synanon Game, internal twelve step program s and other therapeutic modalities ... in the program for one year or more. Modified therapeutic communities are currently used for substance ... 20Lassiter Therapeutic 20Community 20in 20a 20Correctional 20Setting.ppt 1 Therapeutic Community In a Correctional Setting ref , and New York ref http www.asapnys.org TCA.htm Therapeutic Communities ... for Men & Women ref External links http www.eftc europe.com index.htm European Federation of Therapeutic Communities EFTC http www.wftc.org World Federation of Therapeutic Communities WFTC http ...   more details



  1. Therapeutic inertia

    Therapeutic inertia also known as clinical inertia is a measurement of the resistance to Therapy therapeutic treatment for an existing medical condition . It is commonly measured as a percentage of the number of encounters in which a patient with a condition received new or increased therapeutic treatment out of the total number of visits to a health care professional by the patient. A high percentage indicates that the health care provider is slow to treat a medical condition. A low percentage indicates that a provider is extremely quick in prescribing new treatment at the onset of any medical condition. Calculation There are two common methods used in calculating therapeutic inertia. For the following examples, consider that a patient has five visits with a health provider. In four of those visits, a condition is not controlled such as Hypertension high blood pressure or Hypercholesterolemia high cholesterol . In two of those visits, the provider made a change to the patient s treatment for the condition. In Dr. Okonofua s original paper, this patient s therapeutic inertia is calculated as math frac h v frac c v math where h is the number of visits with an uncontrolled condition, c is the number of visits in which a change was made, and v is the total number of visits. ref name ... abstract 47 3 345 title Therapeutic Inertia Is an Impediment to Achieving the Healthy People 2010 ... January 23, 2006 accessdate 2009 11 22 pmid 16432045 ref Therefore, the patient s therapeutic inertia ... condition. The therapeutic inertia is math 1 frac 2 4 0.5 50 math . Reception Therapeutic ... home article view 481 Diabetes care therapeutic inertia in doctors and patients ref and hyperlipidemia ... Targets A Practical Approach to Implementing Therapeutic Lifestyle Changes ref Healthcare feedback reporting processes and intervention studies focused on therapeutic inertia reduction have been shown ... the initial study and reporting on therapeutic inertia. DEFAULTSORT Therapeutic Inertia Category ...   more details



  1. Therapeutic ultrasound

    , ultrasound has been used by physical therapists for therapeutic effects. Physical Therapy Ultrasound ... waves. Therapeutic ultrasound in physical therapy is alternating compression physical compression and rarefaction of sound waves with a frequency of 20,000 cycles second. Therapeutic ultrasound frequency ... electro ultrasound therapeutic ultrasound.htm Watson, T. 2006 . Therapeutic Ultrasound . see http www.electrotherapy.org electro downloads Therapeutic 20Ultrasound.pdf here for a pdf ... effects of therapeutic ultrasound.The two types of effects are thermal and non thermal effects. Thermal ... effects of the inflammatory response. ref Wilkin, H. D., et al. 2004 . Influence of Therapeutic ... Medicine, 25, 73 77. ref Effectiveness of therapeutic ultrasound for pain, musculoskeletal injuries ... A Review of Therapeutic Ultrasound Effectiveness Studies ref References references External links http www.electrotherapy.org electro ultrasound therapeutic ultrasound.htm Watson, T. 2006 . Therapeutic Ultrasound . see http www.electrotherapy.org electro downloads Therapeutic 20Ultrasound.pdf here ... Society for Therapeutic Ultrasound http www.greatlakes physiotherapy.com physiotherapy ultrasound.html ...   more details



  1. Wavelet modulation

    Cleanup date June 2007 Modulation techniques Wavelet modulation , also known as fractal modulation , is a modulation technique that makes use of Wavelet wavelet transformations to represent the data being transmitted. One of the objectives of this type of modulation is to send data at multiple rates over a channel communications channel that is unknown. ref name test http scholar.lib.vt.edu theses available etd 08072001 093853 unrestricted etdset.pdf&aclck http 3A 2F 2Fhomecatalogbiz.com 2Fsr4.php 3Fkeyword 3Dwavelet 2Bmodulation Wavelet Modulation in Gaussian and Rayleigh Fading Channels, Manish J. Manglani , Masters thesis ref If the channel is not clear for one specific bit rate , meaning that the signal will not be received, the signal can be sent at a different bit rate where the signal to noise ratio is higher. See Also Wavelet References reflist DEFAULTSORT Wavelet Modulation Category Quantized radio modulation modes Category Wavelets Telecomm stub de Wavelet Paket Transformation pt Modula o fractal ...   more details



  1. Modulation (disambiguation)

    Modulation is the process of varying one or more properties of a high frequency periodic waveform. Modulation may also refer to Modulation European Union , an authorized reduction in direct aid to producers In science Immunomodulation therapy Neuromodulation In music Modulation music , a change of key Modulations , a multimedia project about the history of electronic music Modulate album Modulate , a rock electronica album by Bob Mould Modulator EP Modulator , an electronica EP by Information Society Modulate band , UK electronic band disambig bg de Modulation et Modulatsioon es Modulaci n fr Modulation he nl Modulatie no Modulasjon andre betydninger ru fi Modulaatio ...   more details



  1. Therapeutic index

    refimprove date May 2010 The therapeutic index also known as therapeutic ratio is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes death in animal ..., it is the ratio given by the lethal or toxic dose divided by the therapeutic dose. In animal studies, the therapeutic index is the lethal dose of a drug for 50 of the population LD50 LD sub 50 ... a toxicity in 50 of the population TD50 TD sub 50 sub is used to calculate the therapeutic index .... A higher therapeutic index is preferable to a lower one a patient would have to take a much higher dose of such a drug to reach the lethal toxic threshold than the dose taken to elicit the therapeutic effect. math mbox Therapeutic ratio frac mathrm LD 50 mathrm ED 50 math in animal studies, or for humans, math mbox Therapeutic ratio frac mathrm TD 50 mathrm ED 50 math Generally, a drug or other therapeutic agent with a narrow therapeutic range i.e. having little difference between toxic and therapeutic ... achieved in the person taking it. This may be achieved through therapeutic drug monitoring TDM protocols. The therapeutic index varies widely among substances most forgiving among the opioid analgesics is remifentanyl , which offers a therapeutic index of 33,000 1 tetrahydrocannabinol , a sedative and analgesic of herbal origin genus Cannabis , has a safe therapeutic index of 1000 1, while diazepam ... available sedative consumed world wide the therapeutic indices for these substances are 15 1 and 10 1 respectively. Even less safe are drugs such as digoxin , a cardiac glycoside its therapeutic ... pmid 17352523 issn 0003 3006 ref Other examples of drugs with a narrow therapeutic range, which may require drug monitoring both to achieve therapeutic levels and to minimize toxicity, include dimercaprol ... amphoterrible for this very reason , and polymyxin B . The effective therapeutic index can be affected by Targeted drug delivery targeting , in which the therapeutic agent is concentrated in its ...   more details



  1. Modulation order

    Unreferenced stub auto yes date December 2009 The modulation order of a digital communication scheme is determined by the number of the different symbols that can be transmitted using it. Modulation order can only be defined for digital modulation s. The simplest forms of digital modulation are of second order because they can transmit only two symbols usually denoted as 0 and 1 or as 1 and 1 . They are called binary shift keying BSK . Modulations which have an order of 4 and above usually are termed as higher order modulation s. Examples of these are quadrature phase shift keying QPSK and its generalisation as m ary quadrature amplitude modulation m QAM . Because existing computers and automation systems are based on binary logic most of the modulations have an order which is a power of two 2, 4, 8, 16, etc. In principle, however, the order of a modulation can be any integer greater than one. When the order of a digital modulation approaches infinity its properties approach those of the respective analog modulation. Thus the analogue modulations can be viewed as extreme cases of higher order digital modulations for which the order is equal to infinity. Category Telecommunication theory DEFAULTSORT Modulation Order Tech stub ...   more details



  1. Therapeutic jurisprudence

    refimprove date March 2010 Therapeutic jurisprudence TJ is a term first used by Professor David Wexler , http www.law.arizona.edu Faculty getprofile.cfm?facultyid 91 University of Arizona Rogers College of Law and University of Puerto Rico School of Law, in a paper delivered to the National Institute of Mental Health in 1987. Along with Professor Bruce Winick , University of Miami School of Law , who originated the concept with Wexler, the professors suggested the need for a new perspective, TJ, to study ... and judge s primarily produce therapeutic or antitherapeutic consequences for individuals involved in the legal process. Black s Law Dictionary , 9th edition, 2009, defines therapeutic jurisprudence ... mental health law, including Wexler and Winick s 1991 book, Essays in Therapeutic Jurisprudence ..., Law in a Therapeutic Key Developments in Therapeutic Jurisprudence. See David B. Wexler, The Development of Therapeutic Jurisprudence From Theory to Practice, 68 Revista Juridica Universidad de Puerto ... and Rosenthal, Therapeutic Jurisprudence and the Drug Treatment Court Movement Revolutionizing ... in their 2003 book, Judging in a Therapeutic Key Therapeutic Jurisprudence and the Courts. Reframing roles Therapeutic Jurisprudence also has been applied in an effort to reframe the role of the lawyer ... Therapeutic Jurisprudence Law as a Helping Profession. TJ also has begun to transform legal education ... issue of the St. Thomas University Law Review, Therapeutic Jurisprudence and Clinical Legal Education and Skills Training. In 2008, Wexler published an edited volume dedicated to therapeutic jurisprudence and the criminal defense attorney. The book is entitled Rehabilitating Lawyers Principles of Therapeutic ... Professor Bruce J. Wincik s webpage http www.aija.org.au Australasian Therapeutic Jurisprudence Clearinghouse http www.therapeuticjurisprudencecenter.org University of Miami Therapeutic Jurisprudence Center http www.wfpl.org 2010 04 01 therapeutic jurisprudence WFPL News State of Affairs on Therapeutic ...   more details



  1. Therapeutic window

    The Therapeutic window or pharmaceutical window of a drug is the range of drug Dose biochemistry dosage s which can treat disease effectively while staying within the safety range. In other words, it is the dosages of a medication between the amount that gives an effect Effective dose pharmacology effective dose and the amount that gives more adverse effects than desired effects ref http www.freepatentsonline.com 20040197415.html freepatentsonline.com ref . For instance, medication with a small pharmaceutical window such as Carbamazepine Tegretol must be administered with care and control, e.g. by frequently measuring blood concentration of the drug, since it easily gives adverse effects such as agranulocytosis ref https online.epocrates.com u 10a1285 Tegretol Bot generated title ref . More specifically, it is the range between the Effective dose pharmacology ED sub 50 sub and the starting point of TD50 TD sub 50 sub curve . It is believed that this index can help to avoid most of the potential adverse effect side effect s. ref Cite web title Therapeutic window Everything2 url http www.everything2.com index.pl?node id 938353 ref It is worth noting that the window can vary by situation. In some cases, the therapeutic window can even be completely closed , meaning that the adverse effects exceed the desired effects at all doses capable of providing the desired effect. ref Cite web title Therapeutic window Everything2 url http www.everything2.com index.pl?node id 938353 ref This is the politicized assertion made by governments that prohibit certain drugs that any dose, they do more harm than good. This index is believed to be more reliable than either the therapeutic index or the protective index , since this index considers the biological variation among individuals to a larger extent. The downside, however, is that it like the protective index also introduces an element of subjectivity. See also Therapeutic index Protective index Certain safety factor References Reflist ...   more details



  1. Space modulation

    Merge to instrument landing system date May 2012 discuss Talk instrument landing system Multiple merges Modulation techniques Space modulation is a radio Amplitude Modulation technique used in Instrument Landing System s that incorporates the use of multiple antennas fed with various radio frequency powers and phases to create different Difference in the Depth of Modulation depths of modulation within various volumes of three dimensional space three dimensional airspace. This modulation method differs from internal modulation methods inside most other radio transmitters in that the phases and powers of the two individual signals mix within airspace, rather than in a modulator. An aircraft with an on board ILS receiver within the capture area of an ILS, glideslope and localiser range , will detect varying depths of modulation according to the aircraft s position within that airspace, providing accurate positional information about the progress to the threshold. Method used to determine aircraft position The ILS uses two radio frequencies, one for each ground station about 110  MHz for LLZ and 330  MHz for the GP , to transmit two Amplitude modulation Amplitude Modulated signals 90  Hz and 150  Hz , along the glidepath GP and the localiser LLZ trajectories into airspace . It is this signal that is projected up from the runway which an aircraft using an instrument approach, uses to land. The modulation depth of each 90  Hz and 150  Hz signal changes according to the deviation of the aircraft from the correct position for the aircraft to touchdown on the threshold. The difference between the two signal modulation depths is zero when the aircraft is on the correct glideslope on approach to the runway i.e. No difference zero Difference in the depth of modulation DDM , produces no deviation from the middle indication of the instrument s needle within the cockpit of the aircraft. See also Difference in the Depth of Modulation Instrument Landing Syste ...   more details



  1. Modulation transformer

    unreferenced date September 2011 A modulation transformer is an Transformer audio frequency transformer that forms a major part of most Amplitude modulation AM transmitters. The primary winding of a modulation transformer is fed by an audio amplifier that has about 1 2 of the rated input power of the transmitter s final amplifier stage. The secondary winding is in series with the power supply of that final radio frequency amplifier stage, thereby lowering and raising the operating voltage of the power amplifier PA tube or transistor. Considering that the PA device is operated as a Electronic amplifier Class C class C amplifier, i.e. as a switch, the modulation transformer is responsible for the amplitude modulation AM of the transmitter. Category Transformers electrical ...   more details



  1. Phase modulation

    Unreferenced date December 2009 Modulation techniques Phase modulation PM is a form of modulation that represents information as variations in the instantaneous phase waves phase of a carrier wave . Unlike its more popular counterpart, frequency modulation FM , PM is not very widely used for radio transmissions. This is because it tends to require more complex receiving hardware and there can be ambiguity problems in determining whether, for example, the signal has changed phase by 180 or 180 . PM is used, however, in digital music synthesizers such as the Yamaha DX7 , even though these instruments are usually referred to as FM synthesizers both modulation types sound very similar, but PM is usually ... of phase modulation. The top diagram shows the modulating signal superimposed on the carrier ... modulation can thus be considered a special case of FM in which the carrier frequency modulation is given by the time derivative of the phase modulation. The mathematics of the spectral density spectral ..., PM is similar to amplitude modulation AM and exhibits its unfortunate doubling of baseband bandwidth ... M omega mathrm m 2 pi math and math h math is the modulation index defined below. This is also known as Carson bandwidth rule Carson s Rule for PM. Modulation index As with other modulation index modulation indices , this quantity indicates by how much the modulated variable varies around its unmodulated ... , math , where math Delta theta math is the peak phase deviation. Compare to the modulation index for frequency modulation Modulation index frequency modulation . See also Angle modulation Automatic frequency control Modulation for a list of other modulation techniques Phase shift keying PSK , the digital version of PM Polar modulation Electro optic modulator for Pockel s Effect phase modulation for applying sidebands to a monochromatic wave DEFAULTSORT Phase Modulation Category Radio modulation ... Modulaci n de fase fr Modulation de phase ko it Modulazione di fase kk lv F zes ...   more details



  1. Therapeutic lying

    Multiple issues wikify March 2012 notability November 2011 orphan February 2009 Therapeutic lying is the controversial practice of lying to patients who repeatedly forget traumatic facts. dead link date November 2011 MEDRS date November 2011 ref cite web url http www.loudountimes.com blogs home caregiver connection 2007 09 11 therapeutic lying or unethical behavior title Therapeutic Lying or Unethical Behavior? ref For instance, a caregiver may tell an Alzheimer s disease patient who inquires about his wife whereabouts that She s gone to the store rather than She died seven years ago. References reflist Category Therapy psychology stub ...   more details



  1. Therapeutic garden

    of Therapeutic Gardens Alzheimer s Gardens adult day care programs and dementia residences Healing ... Meditation Gardens religious institutions and other faith based settings Design The design of a Therapeutic ... and development of Therapeutic Gardens. Depending upon the actual use of the garden, other members .... The majority of elements in a Therapeutic Garden should be plant related, such as perennials .... Plants familiar to those using the Therapeutic Garden need to be non toxic and non injurious. Issues ... and hummingbirds into the Therapeutic Garden, is important. Nature is referred to as a positive distraction ..., and year round interest. Consideration should also be given to the maintenance and upkeep of the Therapeutic ... maintenance of the Therapeutic Garden. Elements The elements of a Therapeutic Garden consist ... 2012 Therapeutic Gardens in literature Healing Gardens Therapeutic Benefits and Design Recommendations Healing Landscapes Therapeutic Outdoor Environments The Healing Landscape Gardening for the Mind ...   more details



  1. Quadrature modulation

    Multiple issues unreferenced October 2008 context October 2009 Quadrature modulation is the general technique of modulating two carriers. Examples include Quadrature amplitude modulation , Phase shift keying , and Minimum shift keying . Constellation diagram s are used to examine the modulation in the 2 D signal space. Explanation Sending a signal by amplitude modulation consists of sending the function math y t I t cdot cos omega c t math where math I t math is the signal to encode and math cos omega c t math is the carrier wave, math omega c math is the carrier frequency one is changing the amplitude of a carrier wave to encode the signal, hence amplitude modulation. In general one could also change the phase of the carrier wave, as in phase modulation there is a dimension of phase that is not being used. In fact, one can encode another signal that is 90 out of phase by using a sine wave, as in math z t I t cdot cos omega c t Q t cdot sin omega c t math this 90 the angle of a rectangle, or a 1 4 turn is why it is called quadrature modulation, and the symbols math I t math and math Q t math indicate the in phase signal and quadrature signal. In terms of Euler s formula , math e it cos t i sin t, math amplitude modulation encodes a 1 dimensional real signal, while quadrature modulation ... modulation exploits. Clocking The added channel capacity is not costless, however. An amplitude modulated ... uses quadrature amplitude modulation , this is conveyed by the color burst , a synchronization signal. By contrast, in polar modulation, clock drift simply degrades the phase modulated signal. Polar modulation Main Polar modulation Quadrature modulates two signals by changing the in phase and quadrature ... modulation is called polar modulation , and was developed earlier, in the 1874 quadruplex telegraph by Thomas Edison . See also Matrix decoder Polar modulation DEFAULTSORT Quadrature Modulation Category Radio modulation modes telecomm stub ...   more details



  1. Therapeutic touch

    PAGENAME Image Caption ICD10 ICD9unlinked MeshID D019124 OPS301 OtherCodes Energy therapy Therapeutic touch commonly shortened to TT , also known as Non Contact Therapeutic Touch NCTT , ref name Astin ... claim promotes healing and reduces pain and anxiety. Practitioners of therapeutic touch state ... s energy field. ref name EoM cite encyclopedia last Bruno first Leonard C. title Therapeutic ... that practitioners of therapeutic touch could not detect the presence or absence of a hand placed ... Sarner url http www.quackwatch.com 01QuackeryRelatedTopics ttdata.html title Therapeutic Touch ... Sarner, Larry and Barrett, Stephen title A Close Look at Therapeutic Touch journal Journal of the American ... Krieger, a nursing educator at New York University , developed therapeutic touch in the 1970s. ref name EoM ref name Quackwatch2 http www.quackwatch.com 01QuackeryRelatedTopics tt.html Why Therapeutic ... n8933645 pg 1 title Consumer access to complementary therapies such as Therapeutic Touch TT publisher Kansas Nurse date March 2001 ref According to Dolores Krieger, practitioners say that therapeutic ... Dolores title Therapeutic Touch The Imprimatur of Nursing journal The American Journal of Nursing volume ... cite book last Krieger first Dolores title Accepting Your Power to Heal The Personal Practice of Therapeutic Touch publisher Bear & Company date April 1, 1993 pages 7 isbn 1879181045 ref Therapeutic .... ref Scientific investigations Researching therapeutic touch in 1996, the James Randi Educational ... that one test on one practitioner is not grounds to dismiss the entire theory of therapeutic ... a study on therapeutic touch. With the help of Stephen Barrett from Quackwatch , and with the assistance ... accepted by the Journal of the American Medical Association JAMA for her part in a study of therapeutic touch, which debunker debunked the claims of therapeutic touch practitioners. Twenty one practitioners of therapeutic touch participated in her study, and they attempted to detect her aura. The practitioners ...   more details




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