Image Mercapto Group General Formulae.png thumb 120px right Thiol with a span style color blue blue span highlighted sulfhydryl group. In organic chemistry, a thiol IPAc en icon a , l is an organosulfur ... group itself is referred to as either a thiol group or a sulfhydryl group . Many thiols have strong ... gas which in pure form is odorless , and the smell of natural gas is due to the smell of the thiol ... of the thiol group Saul Patai, Ed. Wiley, London, 1974. ISBN 0471669490. ref ref name CremlynAn ... liquids, the hydrogen bonding between individual thiol groups is weak, the main cohesive force being ... The preferred method used by the IUPAC is to add the suffix thiol to the name of the alkane ... of skunk s consists mainly of low molecular weight thiol compounds. ref cite journal journal Journal ... MeSCH sub 2 sub SH MTMT is a strong smelling volatile thiol, also detectable at parts per billion ... monoterpenoid thiol, is responsible for the characteristic scent of grapefruit . The effect of the latter ... in thiol disulfide exchange RS SR 2 R SH 2 RSH R S SR This reaction is especially important in nature ... Free radical s derived from mercaptans, called thiyl or thiol radical or mercapto radical, are commonly ... group of the amino acid cysteine , the thiol group plays a very important role in biology. When the thiol groups of two cysteine residues as in monomers or constituent units are brought near each ... a thioester derived from the thiol Coenzyme A . The biosynthesis of methane , the principal hydrocarbon ... multicol end See also Doctor sweetening process Odorizer Thiol disulfide exchange Footnotes ... Functional groups Category Organic compounds ar ca Tiol cs Thiol da Thiol de Thiole et Tioolid es Tiol eo Merkaptanoj fa fr Thiol gl Tiol id Tiol it Mercaptani he hu Tiolok mk nl Thiol ja no Tiol pl Tiole pt Tiol ru sk Tiol sl Tiol sr Tiol fi Tiolit sv Tiol uk vi Thiol zh ... more details
enzyme Name thiol S methyltransferase EC number 2.1.1.9 CAS number 9029 81 6 IUBMB EC number 2 1 1 9 GO code 0018708 image width caption In enzymology , a thiol S methyltransferase EC number 2.1.1.9 is an enzyme that catalysis catalyzes the chemical reaction S adenosyl L methionine a thiol math rightleftharpoons math S adenosyl L homocysteine a thioether Thus, the two substrate biochemistry substrates of this enzyme are S Adenosyl methionine S adenosyl methionine and thiol , whereas its two product chemistry products are S adenosylhomocysteine and thioether . This enzyme belongs to the family of transferase s, specifically those transferring one carbon group methyltransferases. The systematic name of this enzyme class is S adenosyl L methionine thiol S methyltransferase . Other names in common use include S methyltransferase , thiol methyltransferase , and TMT . This enzyme participates in selenoamino acid metabolism . References reflist 1 cite journal author Borchardt RT, Cheng CF date 1978 title Purification and characterization of rat liver microsomal thiol methyltransferase journal Biochim. Biophys. Acta. volume 522 pages 340&ndash 53 pmid 623768 issue 2 cite journal author Bremer J and Greenberg DM date 1961 title Enzymic methylation of foreign sulfhydryl compounds journal Biochim. Biophys. Acta volume 46 issue 2 pages 217&ndash 224 doi 10.1016 0006 3002 61 90746 6 cite journal author Weisiger RA, Jakoby WB date 1979 title Thiol S methyltransferase from rat liver journal Arch. Biochem. Biophys. volume 196 pages 631&ndash 7 pmid 485170 doi 10.1016 0003 9861 79 90317 5 issue 2 transferase stub Category EC 2.1.1 Category Enzymes of unknown structure it Tiolo S metiltransferasi ja S ... more details
enzyme Name Thiol sulfotransferase EC number 2.8.2.16 CAS number 70356 45 5 IUBMB EC number 2 8 2 16 GO code image width caption In enzymology , a thiol sulfotransferase EC number 2.8.2.16 is an enzyme that catalysis catalyzes the chemical reaction 3 phosphoadenylyl sulfate a thiol math rightleftharpoons math adenosine 3 ,5 bisphosphate an S alkyl thiosulfate Thus, the two substrate biochemistry substrates of this enzyme are 3 phosphoadenylyl sulfate and thiol , whereas its two product chemistry products are adenosine 3 ,5 bisphosphate and S alkyl thiosulfate . This enzyme belongs to the family of transferase s, specifically the sulfotransferases, which transfer sulfur containing groups. The systematic name of this enzyme class is 3 phosphoadenylyl sulfate thiol S sulfotransferase . Other names in common use include phosphoadenylylsulfate thiol sulfotransferase , PAPS sulfotransferase , and adenosine 3 phosphate 5 sulphatophosphate sulfotransferase . References reflist 1 cite journal author Schmidt A date 1976 title The adenosine 5 phosphosulfate sulfotransferase from spinach Spinacea oleracea L. . Stabilization, partial purification, and properties journal Planta volume 130 pages 257&ndash 263 doi 10.1007 BF00387830 issue 3 cite journal author Schmidt A and Christen U date 1979 title A PAPS dependent sulfotransferase in Cyanophora paradoxa inhibited by 5 AMP, 5 ADP and APS journal Z. Naturforsch. C Biosci. volume 34 pages 222&ndash 228 cite journal author Tsang M date 1976 title L. S. and Schiff, J.A. Studies of sulfate utilization by algae. 17 Reactions of the adenosine 5 phosphosulfate APS sulfotransferase from Chlorella and studies of model reactions which explain the diversity of side products with thiols journal Plant Cell Physiol. volume 17 pages 1209&ndash 1220 transferase stub Category EC 2.8.2 Category Enzymes of unknown structure ... more details
enzyme Name thiol oxidase EC number 1.8.3.2 CAS number 9029 39 4 IUBMB EC number 1 8 3 2 GO code 0016972 image width caption In enzymology , a thiol oxidase EC number 1.8.3.2 is an enzyme that catalysis catalyzes the chemical reaction 4 R C R SH O sub 2 sub math rightleftharpoons math 2 R C R S S R CR 2 H sub 2 sub O Thus, the two substrate biochemistry substrates of this enzyme are R C R SH and oxygen O sub 2 sub , whereas its two product chemistry products are R C R S S R CR and water H sub 2 sub O . This enzyme belongs to the family of oxidoreductase s, specifically those acting on a sulfur group of donors with oxygen as acceptor. The systematic name of this enzyme class is thiol oxygen oxidoreductase . This enzyme is also called sulfhydryl oxidase . References reflist 1 cite journal author AURBACH GD, JAKOBY WB date 1962 title The multiple functions of thiooxidase journal J. Biol. Chem. volume 237 pages 565&ndash 8 pmid 13863296 cite journal author NEUFELD HA, GREEN LF, LATTERELL FM, WEINTRAUB RL date 1958 title Thioxidase, a new sulfhydryl oxidizing enzyme from Piricularia oryzae and Polyporus versicolor journal J. Biol. Chem. volume 232 pages 1093&ndash 9 pmid 13549489 issue 2 1.8 enzyme stub Category EC 1.8.3 Category Enzymes of unknown structure it Tiolo ossidasi ja ... more details
Orphan date September 2010 Pfam box Symbol Thiol cytolysin Name Thiol activated cytolysin Pfam PF01289 InterPro IPR001869 PROSITE PDOC00436 OPM family 116 OPM protein 1pfo PDB Thiol activated cytolysins ref name PUB00002128 Cite journal author Geoffroy C, Mengaud J, Cossart P, Alouf JE title Alveolysin, the thiol activated toxin of Bacillus alvei, is homologous to listeriolysin O, perfringolysin O, pneumolysin, and streptolysin O and contains a single cysteine journal J. Bacteriol. volume 172 issue 12 pages 7301 7305 year 1990 pmid 2254290 ref ref name PUB00006593 Cite journal author Geoffroy C, Alouf JE title journal volume issue pages 165 171 year 1984 ref are toxins produced by a variety of Gram positive bacteria and are characterised by their ability to lyse cholesterol containing membranes, their reversible inactivation by oxidation and their capacity to bind to cholesterol. All these proteins contain a single cysteine residue, located in their C terminal section, which has been shown ref name PUB00001356 Cite journal author Iwamoto M, Ohno Iwashita Y, Ando S title Role of the essential thiol group in the thiol activated cytolysin from Clostridium perfringens journal Eur. J. Biochem. volume 167 issue 3 pages 425 430 year 1987 pmid 2888650 doi 10.1111 j.1432 1033.1987.tb13355.x ref to be essential for the binding to cholesterol. References Reflist InterPro content IPR001869 Category Bacterial toxins ... more details
The Thiol yne reaction also alkyne hydrothiolation is an organic reaction between a thiol and an alkyne . The reaction product is an alkenyl sulfide. ref name March1985 JerryMarch ref ref name Hoogenboom2010 cite journal doi 10.1002 anie.201000401 pmid 20394091 title Thiol Yne Chemistry A Powerful Tool for Creating Highly Functional Materials year 2010 last1 Hoogenboom first1 Richard journal Angewandte Chemie International Edition volume 49 issue 20 pages 3415 7 ref The reaction was first reported ... cite journal doi 10.1021 ma801903w title Thiol Yne Photopolymerizations Novel Mechanism, Kinetics ... wikitable align center File Thiol yne reaction.svg center 300px Thiol yne reaction align center Thiol yne reaction This addition reaction is typically facilitated by a radical initiator or UV ... A General volume 375 pages 49 ref class wikitable align center File Ichinose thiol yne 1987.svg center 400px Ichinose et al. thiol yne reaction 1987 align center Ichinose et al. thiol yne reaction ... doi 10.1021 ja908206a title Hyperbranched Polymers by Thiol Yne Chemistry From Small Molecules to Functional ... synthesis of dendrimers via a thiol yne and esterification process and their potential application ... ref ref name Yu2009 cite journal doi 10.1002 pola.23436 title Sequential thiol ene thiol ene and thiol ene thiol yne reactions as a route to well defined mono and bis end functionalized poly N isopropylacrylamide ... pages 3544 issue 14 ref in star polymer s, ref Thiol yne click chemistry as a route to functional lipid ... Polym. Chem., 2011, DOI 10.1039 C0PY00231C ref ref Luminescent Hyperbranched Polymers Combining Thiol ... thiol yne core functionalization crosslinking of block copolymer micelles DOI 10.1039 C1PY00002K ... title Clicking Polymer Brushes with Thiol yne Chemistry Indoors and Out year 2009 last1 Hensarling ... 41 ref block copolymer s ref Hyperbranched alternating block copolymers using thiol yne chemistry ... and a Rotaxane through Thiol yne Click and Dithiol Coupling Reactions Weidong Zhou, Haiyan Zheng, Yongjun ... more details
enzyme Name thiosulfate thiol sulfurtransferase EC number 2.8.1.3 CAS number 111070 24 7 IUBMB EC number 2 8 1 3 GO code 0050337 image width caption In enzymology , a thiosulfate thiol sulfurtransferase EC number 2.8.1.3 is an enzyme that catalysis catalyzes the chemical reaction thiosulfate 2 glutathione math rightleftharpoons math sulfite glutathione disulfide sulfide Thus, the two substrate biochemistry substrates of this enzyme are thiosulfate and glutathione , whereas its 3 product chemistry products are sulfite , glutathione disulfide , and sulfide . This enzyme belongs to the family of transferase s, specifically the sulfurtransferases, which transfer sulfur containing groups. The systematic name of this enzyme class is thiosulfate thiol sulfurtransferase . Other names in common use include glutathione dependent thiosulfate reductase , sulfane reductase , and sulfane sulfurtransferase . This enzyme participates in glutathione metabolism . References reflist 1 cite journal author PECK HD Jr, FISHER E Jr date 1962 title The oxidation of thiosulfate and phosphorylation in extracts of Thiobacillus thioparus journal J. Biol. Chem. volume 237 pages 190&ndash 7 pmid 14484816 cite journal author Sido B and Koj A date 1972 title Separation of rhodanese and thiosulfate reductase activities in carp liver extracts journal Acta Biol. Cracow Ser. Zoo. volume 15 pages 97&ndash 103 cite journal author Uhteg LC, Westley J date 1979 title Purification and steady state kinetic analysis of yeast thiosulfate reductase journal Arch. Biochem. Biophys. volume 195 pages 211&ndash 22 pmid 383018 doi 10.1016 0003 9861 79 90343 6 issue 1 transferase stub Category EC 2.8.1 Category Enzymes of unknown structure ... more details
enzyme Name enzyme thiol transhydrogenase glutathione disulfide EC number 1.8.4.7 CAS number 85030 79 1 IUBMB EC number 1 8 4 7 GO code 0047142 image width caption In enzymology , an enzyme thiol transhydrogenase glutathione disulfide EC number 1.8.4.7 is an enzyme that catalysis catalyzes the chemical reaction xanthine dehydrogenase glutathione disulfide math rightleftharpoons math xanthine oxidase 2 glutathione Thus, the two substrate biochemistry substrates of this enzyme are xanthine dehydrogenase and glutathione disulfide , whereas its two product chemistry products are xanthine oxidase and glutathione . This enzyme belongs to the family of oxidoreductase s, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is xanthine dehydrogenase glutathione disulfide S oxidoreductase . Other names in common use include xanthine dehydrogenase oxidized glutathione S oxidoreductase , enzyme thiol transhydrogenase oxidized glutathione , glutathione dependent thiol disulfide oxidoreductase , and thiol disulfide oxidoreductase . This enzyme participates in glutathione metabolism . References reflist 1 cite journal author Battelli MG, Lorenzoni E date 1982 title Purification and properties of a new glutathione dependent thiol disulphide oxidoreductase from rat liver journal Biochem. J. volume 207 pages 133&ndash 8 pmid 6960894 issue 1 pmc 1153833 1.8 enzyme stub Category EC 1.8.4 Category Enzymes of unknown structure it Enzima tiolo transidrogenasi glutatione disolfuro ja ... more details
Thioenols also known as alkenthiols are alkene s with a thiol group affixed to one of the carbon atoms composing the double bond . Alkenes with a thiol group on both sides of the double bond are called enedithiols . Deprotonation Deprotonated anions of thioenols are called thioenolates . The C C double bond with adjacent alcohol gives thioenols and enedithiols their chemical characteristics, by which they present keto enol tautomerism . In keto enol tautomerism, thioenols interconvert with thioketone s or thioaldehyde s. The words thioenol and alkenthiol come from the words alkene or just ene , the suffix given to C C double bonded alkenes and thiol which represents the thioenol s thiol group . Thioketo thioenol tautomerism Thioenols interconvert with thio carbonyl compound s that have an hydrogen , like thioketone s and thioaldehyde s. The compound is Deprotonation deprotonated on one side and Protonation protonated on another side, whereas a single bond and a double bond are exchanged. This is called keto enol tautomerism . See also Enol External links http www.nrcresearchpress.com doi abs 10.1139 v98 027 Canadian journal of chemistry Category Sulfur compounds ... more details
Unreferenced stub auto yes date December 2009 Thiolysis is a reaction with a thiol R SH that cleaves one compound into two. This reaction is similar to hydrolysis , which involves water instead of a thiol . This reaction is seen in beta oxidation &beta oxidation of fatty acid s. The depolymerisation of condensed tannin s with the use of benzyl mercaptan as nucleophile is also called thiolysis. Image FattyAcid MB Thiolysis.png center frame Example of thiolysis thiol CoA SH References reflist Category Substitution reactions Category Chemical techniques for the analysis of tannins Reaction stub es Ti lisis ... more details
RSH may mean The NYSE stock symbol for RadioShack Roomi S. Hayat Remote shell , a UNIX command line utility for remotely executing commands Restricted shell , a restricted shell environment for Unix Robert Stephenson and Hawthorns , a locomotive manufacturer Royal South Hampshire Hospital in Southampton The graffiti tag of artist Raymond Salvatore Harmon R SH, within organic chemistry, the notation used for a compound also known as Thiol disambig de RSH fr RSH it RSH sr RSH ... more details
Ellman may refer to John Ellman , the agriculturalist of Glynde who developed the Southdown sheep Southdown breed of sheep. Louise Ellman Mark Ellman , see Maui Tacos Ellman s Ellman s reagent , a chemical compound used to quantify the number or concentration of thiol groups in a sample Michael Ellman Dutch economist See also Elman disambiguation Richard Ellmann disambig de Ellman ... more details
s, which become reduced during the thiol disulfide exchange reactions that oxidise the cysteine thiol ... Cys X X Cys X X Cys where X can be any residue . The mechanism of thiol disulfide exchange between oxidoreductases The mechanism of thiol disulfide exchange between oxidoreductases is understood to begin ... transferred from Ero1 via a thiol disulfide exchange reaction to PDI, with PDI then undergoing a thiol disulfide exchange with the nascent polypeptide, thereby enabling the formation of disulfide ... more details
Hemithioacetals are ordinarily unstable because they readily dissociate into thiol and aldehyde ... of thiol to methyl glyoxalate. ref Milton, J Brand, S Jones, M.F Rayner, C.M., Tetrahedron ... uses carbonyl groups that form stable hydrates. For example, a thiol R SH reacts with hexafluoroacetone ... more details
in 2007, as an unidentified thiol in Bacillus anthracis . ref Cite pmid 17323930 ref The naturally occurring free thiol form of bacillithiol has since been synthesised and characterised along with its ... A Unique Low Molecular Weight Thiol amongst Low G C Gram Positive Bacteria journal Angew. Chem ... thiol in other organisms. ref name Newton Some of genes involved in the biosynthesis of bacillithiol ... weight thiol in Bacilli journal Proc. Natl. Acad. Sci. U.S.A. volume 107 issue 14 pages 6482 6 year ... Furthermore, in vitro kinetic studies have established that bacillithiol is a preferred thiol ... more details
enzyme Name citrate pro 3S lyase ligase EC number 6.2.1.22 CAS number 52660 22 7 IUBMB EC number 6 2 1 22 GO code 0008771 image width caption In enzymology , a citrate pro 3S lyase ligase EC number 6.2.1.22 is an enzyme that catalysis catalyzes the chemical reaction ATP acetate citrate pro 3S lyase thiol form math rightleftharpoons math AMP diphosphate citrate pro 3S lyase acetyl form The 3 substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP , acetate , and citrate pro 3S lyase thiol form , whereas its 3 product chemistry products are adenosine monophosphate AMP , diphosphate , and citrate pro 3S lyase acetyl form . This enzyme belongs to the family of ligase s, specifically those forming carbon sulfur bonds as acid thiol ligases. The systematic name of this enzyme class is acetate citrate pro 3S lyase thiol form ligase AMP forming . Other names in common use include citrate lyase ligase , citrate lyase synthetase , acetate SH acyl carrier protein enzyme ligase AMP , acetate HS citrate lyase ligase , and acetate citrate pro 3S lyase thiol form ligase AMP forming . This enzyme participates in two component system general . References reflist 1 cite journal author Antranikian G, Gottschalk G date 1982 title Copurification of citrate lyase and citrate lyase ligase from Rhodopseudomonas gelatinosa and subsequent separation of the two enzymes journal Eur. J. Biochem. volume 126 pages 43&ndash 7 pmid 7128585 doi 10.1111 j.1432 1033.1982.tb06743.x issue 1 cite journal author Antranikian G, Herzberg C, Gottschalk G date 1985 title Covalent modification of citrate lyase ligase from Clostridium sphenoides by phosphorylation dephosphorylation journal Eur. J. Biochem. volume 153 pages 413&ndash 20 pmid 3935436 doi 10.1111 j.1432 1033.1985.tb09318.x issue 2 cite journal author Quentmeier A, Antranikian G date 1985 title Characterization of citrate lyase from Clostridium sporosphaeroides journal Arch. Microbiol. volume 141 pages 85&ndash 90 pmid 399448 ... more details
chembox verifiedrevid 427110901 ImageFile BrBM.png ImageSize ImageFile1 Bromobimane 3D spacefill.png IUPACName 3 bromomethyl 2,5,6 trimethyl 1 H ,7 H br pyrazolo 1,2 a pyrazole 1,7 dione OtherNames Bromobimane, mBBr Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 102775 InChI 1 C10H11BrN2O2 c1 5 7 3 12 8 4 11 6 2 10 15 13 12 9 5 14 h4H2,1 3H3 InChIKey AHEWZZJEDQVLOP UHFFFAOYAR StdInChI Ref stdinchicite correct chemspider StdInChI 1S C10H11BrN2O2 c1 5 7 3 12 8 4 11 6 2 10 15 13 12 9 5 14 h4H2,1 3H3 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey AHEWZZJEDQVLOP UHFFFAOYSA N CASNo Ref cascite correct ?? CASNo 71418 44 5 PubChem 114810 SMILES O C1 C C N2 C C C O N12 C CBr C C Section2 Chembox Properties C 10 H 11 Br 1 N 2 O 2 Appearance Density MeltingPt 152 154 C BoilingPt Solubility in MeOH, Dimethylformamide DMF , dimethyl sulfoxide DMSO Section3 Chembox Hazards MainHazards alkylating agent FlashPt Autoignition Bromobimane or monobromobimane is a heterocyclic compound and bimane dye that is used as a reagent in biochemistry . It alkylate s thiol groups, displacing the bromine and adding the fluorescent tag sub emission sub 478 nm to the thiol. Its alkylating properties are comparable to iodoacetamide . ref cite journal author Paul C. Chinn, Vincent Pigiet, and Robert C. Fahey title Determination of thiol proteins using monobromobimane labeling and high performance liquid chromatographic analysis Application to Escherichia coli thioredoxin journal Analytical Biochemistry year 1986 volume 159 pages 143 149 doi 10.1016 0003 2697 86 90319 2 pmid 3544950 issue 1 ref References references Category Alkylating agents Category Organobromides Category Lactams Category Hydrazides ... more details
enzyme Name cysteine S conjugate beta lyase EC number 4.4.1.13 CAS number 68652 57 3 IUBMB EC number 4 4 1 13 GO code 0047804 image width caption In enzymology , a cysteine S conjugate beta lyase EC number 4.4.1.13 is an enzyme that catalysis catalyzes the chemical reaction RS CH sub 2 sub CH NH sub 3 sub COO math rightleftharpoons math RSH NH sub 3 sub pyruvate Hence, this enzyme has one substrate biochemistry substrate , RS CH2 CH NH3 COO , but 3 product chemistry products RSH , ammonia NH sub 3 sub , and pyruvate . This enzyme belongs to the family of lyase s, specifically the class of carbon sulfur lyases. The systematic name of this enzyme class is L cysteine S conjugate thiol lyase deaminating pyruvate forming . Other names in common use include cysteine conjugate beta lyase , glutamine transaminase K cysteine conjugate beta lyase , and L cysteine S conjugate thiol lyase deaminating . It employs one cofactor biochemistry cofactor , pyridoxal phosphate . Structural studies As of late 2007, 3 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1W7L , PDB link 1W7M , and PDB link 1W7N . References reflist 1 cite journal author Tateishi M, Suzuki S, Shimizu H date 1978 title Cysteine conjugate beta lyase in rat liver. A novel enzyme catalyzing formation of thiol containing metabolites of drugs journal J. Biol. Chem. volume 253 pages 8854&ndash 9 pmid 721818 issue 24 lyase stub Category EC 4.4.1 Category Pyridoxal phosphate enzymes Category Enzymes of known structure ... more details
enzyme Name S alkylcysteine lyase EC number 4.4.1.6 CAS number 62213 27 8 IUBMB EC number 4 4 1 6 GO code 0050271 image width caption In enzymology , a S alkylcysteine lyase EC number 4.4.1.6 is an enzyme that catalysis catalyzes the chemical reaction an S alkyl L cysteine H sub 2 sub O math rightleftharpoons math an alkyl thiol NH sub 3 sub pyruvate Thus, the two substrate biochemistry substrates of this enzyme are S alkyl L cysteine and water H sub 2 sub O , whereas its 3 product chemistry products are alkyl thiol , ammonia NH sub 3 sub , and pyruvate . This enzyme belongs to the family of lyase s, specifically the class of carbon sulfur lyases. The systematic name of this enzyme class is S alkyl L cysteine alkyl thiol lyase deaminating pyruvate forming . Other names in common use include S alkylcysteinase , alkylcysteine lyase , S alkyl L cysteine sulfoxide lyase , S alkyl L cysteine lyase , S alkyl L cysteinase , alkyl cysteine lyase , and S alkyl L cysteine alkylthiol lyase deaminating . It employs one cofactor biochemistry cofactor , pyridoxal phosphate . References reflist 1 cite journal author Nomura J, Nishizuka Y and Hayaishi O date 1963 title S Alkylcysteinase enzymatic cleavage of S methyl L cysteine and its sulfoxide journal J. Biol. Chem. volume 238 pages 1441&ndash 1446 enzyme stub Category EC 4.4.1 Category Pyridoxal phosphate enzymes Category Enzymes of unknown structure ... more details
chembox verifiedrevid 349493724 ImageFile Thiazolidine numbering.png ImageSize 100px IUPACName Thiazolidine OtherNames Section1 Chembox Identifiers CASNo 504 78 9 PubChem 10444 SMILES C1CSCN1 Section2 Chembox Properties Formula C sub 3 sub H sub 7 sub NS MolarMass 89.16 g mol Appearance Density 1.131 g cm sup 3 sup MeltingPt BoilingPt 72 75 C at 25 torr Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Thiazolidines are a class of heterocyclic organic compound s with a 5 membered saturation chemistry saturated ring with a thioether group and an amine group in the 1 and 3 positions, respectively. It is a sulfur analogue of oxazolidine . The drug pioglitazone contains a thiazolidine ring. It is a drug usually indicated in cases of type II diabetes for decreasing blood sugar. It also decreases triglycerides and C reactive protein levels. It lowers blood pressure and increases levels of HDL. Another drug which contains a thiazolidine ring is the antibiotic drug penicillin. Thiazolidines may be synthesized by a condensation reaction between a thiol and an aldehyde or ketone . The reaction is reversible. Therefore, many thiazolidines are labile towards hydrolysis in aqueous solution. Hydrolysis of the thiazolidine generates the thiol and aldehyde or ketone from which it was synthesized. References heterocyclic stub Category Thiazolidines de Thiazolidin fa nl Thiazolidine pl Tiazolidyna ... more details
enzyme Name L tartrate dehydratase EC number 4.2.1.32 CAS number 9014 40 8 IUBMB EC number 4 2 1 32 GO code 0008730 image width caption In enzymology , a L tartrate dehydratase EC number 4.2.1.32 is an enzyme that catalysis catalyzes the chemical reaction R,R tartrate math rightleftharpoons math oxaloacetate H sub 2 sub O Hence, this enzyme has one substrate biochemistry substrate , R,R tartrate , and two product chemistry products , oxaloacetate and water H sub 2 sub O . This enzyme belongs to the family of lyase s, specifically the hydro lyases, which cleave carbon oxygen bonds. The systematic name of this enzyme class is R,R tartrate hydro lyase oxaloacetate forming . Other names in common use include tartrate dehydratase , tartaric acid dehydrase , L tartrate dehydratase , L tartaric acid dehydratase , and R,R tartrate hydro lyase . This enzyme participates in glyoxylate and dicarboxylate metabolism . It has 2 cofactor biochemistry cofactors iron , and Thiol . References reflist 1 cite journal author HURLBERT RE, JAKOBY WB date 1965 title TARTARIC ACID METABOLISM. I. SUBUNITS OF L TARTARIC ACID DEHYDRASE journal J. Biol. Chem. volume 240 pages 2772&ndash 7 pmid 14342293 4.2 enzyme stub Category EC 4.2.1 Category Iron enzymes Category Thiol enzymes Category Enzymes of unknown structure ... more details
enzyme Name citrate pro 3S lyase thiolesterase EC number 3.1.2.16 CAS number 58319 93 0 IUBMB EC number 3 1 2 16 GO code 0047778 image width caption In enzymology , a citrate lyase deacetylase EC number 3.1.2.16 is an enzyme that catalysis catalyzes the chemical reaction citrate pro 3S lyase acetyl form H sub 2 sub O math rightleftharpoons math citrate pro 3S lyase thiol form acetate Thus, the two substrate biochemistry substrates of this enzyme are citrate pro 3S lyase acetyl form and water H sub 2 sub O , whereas its two product chemistry products are citrate pro 3S lyase thiol form and acetate . This enzyme belongs to the family of hydrolase s, specifically those acting on thioester bonds. The systematic name of this enzyme class is citrate pro 3S lyase acetyl form hydrolase . This enzyme is also called citrate pro 3S lyase thiolesterase . References reflist 1 cite journal author Giffhorn F, Rode H, Kuhn A, Gottschalk G date 1980 title Citrate lyase deacetylase of Rhodopseudomonas gelatinosa. Isolation of the enzyme and studies on the inhibition by L glutamate journal Eur. J. Biochem. volume 111 pages 461&ndash 71 pmid 7460909 doi 10.1111 j.1432 1033.1980.tb04961.x issue 2 hydrolase stub Category EC 3.1.2 Category Enzymes of unknown structure ... more details
enzyme Name S succinylglutathione hydrolase EC number 3.1.2.13 CAS number 50812 22 1 IUBMB EC number 3 1 2 13 GO code 0050273 image width caption In enzymology , a S succinylglutathione hydrolase EC number 3.1.2.13 is an enzyme that catalysis catalyzes the chemical reaction S succinylglutathione H sub 2 sub O math rightleftharpoons math glutathione succinate Thus, the two substrate biochemistry substrates of this enzyme are S succinylglutathione and water H sub 2 sub O , whereas its two product chemistry products are glutathione and succinate . This enzyme belongs to the family of hydrolase s, specifically those acting on thioester bonds. The systematic name of this enzyme class is S succinylglutathione hydrolase . References reflist 1 refbegin cite journal author Uotila L date 1973 title Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases journal Biochemistry. volume 12 pages 3938 3943 pmid 4200890 doi 10.1021 bi00744a024 issue 20 cite journal author Uotila L date 1979 title Purification and properties of S succinylglutathione hydrolase from human liver journal J. Biol. Chem. volume 254 pages 7024 9 pmid 457667 issue 15 refend refbegin hydrolase stub Category EC 3.1.2 Category Enzymes of unknown structure ... more details
A., Hener U., Mosandl A. title Stereoisomeric flavor compounds. LXX 1 p menthene 8 thiol separation ... aromatic compound in grapefruit Terpineol , where a hydroxyl is in place of the thiol References ... more details
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