chembox Verifiedfields changed verifiedrevid 470609135 ImageFile Thiouracil.png ImageSize 120px IUPACName 2 thioxo 1H pyrimidin 4 one OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 1066108 UNII Ref fdacite correct FDA UNII 59X161SCYL InChI 1 C4H4N2OS c7 3 1 2 5 4 8 6 3 h1 2H, H2,5,6,7,8 InChIKey ZEMGGZBWXRYJHK UHFFFAOYAK ChEMBL Ref ebicite correct EBI ChEMBL 345768 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C4H4N2OS c7 3 1 2 5 4 8 6 3 h1 2H, H2,5,6,7,8 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey ZEMGGZBWXRYJHK UHFFFAOYSA N CASNo Ref cascite correct CAS CASNo 141 90 2 PubChem 1269845 ChEBI Ref ebicite correct EBI ChEBI 348530 SMILES O C1 C C NC S N1 MeSHName Thiouracil KEGG Ref keggcite changed kegg KEGG C19304 Section2 Chembox Properties Formula C sub 4 sub H sub 4 sub N sub 2 sub OS MolarMass 128.153 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Thiouracil refers both to a specific molecule consisting of a sulfated uracil , and a family of molecules based upon that structure. The substance is a historically relevant antithyroid preparation. Astwood E.B. used it in 1943 as therapy of Graves disease for the first time. ref name q1 http books.google.com books?id LLoOUP y54YC&pg PA152&dq parry struma&hl de&sig bThK7levfOnNREWbw20F2Oddz7Q Gerabek W. Enzyklop die Medizingeschichte, S 152, 2005 ref It remains in use. References references Thyroid therapy Category Pyrimidines Category IARC Group 2B carcinogens Category Thioureas heterocyclic stub de Thiouracil fa ... more details
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