PBB geneid 121340 Transcriptionfactor Sp7 is a protein that in humans is encoded by the SP7 gene . ref name pmid11792318 cite journal author Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B title The novel zinc finger containing transcriptionfactor osterix is required for osteoblast differentiation and bone formation journal Cell volume 108 issue 1 pages 17 29 year 2002 month Jan pmid 11792318 pmc doi 10.1016 S0092 8674 01 00622 5 ref ref name entrez The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text SP7 is a C2H2 type zinc finger transcriptionfactor of the SP gene family and a putative master regulator of bone cell differentiation Gao et al., 2004 . supplied by OMIM ref name entrez cite web title Entrez Gene SP7 Sp7 transcriptionfactor url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 121340 accessdate ref References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Strausberg RL, Feingold EA, Grouse LH, et al. title Generation and initial analysis of more than 15,000 full length human and mouse cDNA sequences. journal Proc. Natl. Acad. Sci. U.S.A. volume 99 issue 26 pages 16899 903 year 2003 pmid 12477932 doi 10.1073 pnas.242603899 pmc 139241 cite journal author Gronthos S, Chen S, Wang CY, et al. title Telomerase accelerates osteogenesis of bone marrow stromal stem cells ... 9 cite journal author Amorim BR, Okamura H, Yoshida K, et al. title The transcriptional factor Osterix ... year 2007 pmid 17352693 doi 10.1042 BJ20070104 refend External links MeshName Sp12 TranscriptionFactorTranscription factors g2 The PBB Controls template provides controls for Protein Box Bot, please ... 4 43 cite journal author Gao Y, Jheon A, Nourkeyhani H, et al. title Molecular cloning, structure, expression ... protein box yes update summary yes update citations yes Category Transcription factors gene 12 ... more details
Function Basic helix loop helix bHLH transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcriptionfactor and shares similarity with another bHLH transcriptionfactor, Dermo1 a.k.a. TWIST2 . The strongest expression ... RNA directed against TWIST, a novel zinc finger transcriptionfactor, increases A549 cell sensitivity ... name pmid19513566 cite journal author Okamura H, Yoshida K, Haneji T title Negative regulation of TIMP1 is mediated by transcriptionfactor TWIST1 journal Int. J. Oncol. volume 35 issue 1 pages 181 6 year 2009 month July pmid 19513566 doi ref Interactions Twist transcriptionfactor has been shown to Protein ..., a basic helix loop helix transcriptionfactor, in Saethre Chotzen syndrome. journal Nat. Genet ... GeneReviews NCBI.NIH.UW entry on Saethre Chotzen Syndrome MeshName Twist transcriptionfactor DEFAULTSORT Twist TranscriptionFactor NLM content Transcription factors g1 gene 7 stub Category Transcription ... A, S rensen N, Krauss J, Collmann H title Saethre Chotzen syndrome caused by TWIST 1 gene mutations ... 00 00380 X cite journal author Dollfus H, Kumaramanickavel G, Biswas P, et al. title Identification ... more details
Infobox protein family Symbol DP Name DP image PDB 2aze EBI.jpg width caption structure of the rb c terminal domain bound to an e2f1 dp1 heterodimer Pfam PF08781 Pfam clan InterPro IPR014889 SMART PROSITE PDOC00359 MEROPS S9 SCOP 1c5e TCDB OPM family OPM protein CAZy GT1 CDD In molecular biology, transcription factor DP is a family of proteins which function as transcription factors . DP forms a heterodimer with E2F and Transcriptional regulation regulate s genes involved in cell cycle progression. The Transcription genetics transcriptional activity of E2F is inhibited by the retinoblastoma protein which Molecular binding bind s to the E2F DP heterodimer ref name pmid16360038 cite journal author Rubin SM, Gall AL, Zheng N, Pavletich NP title Structure of the Rb C terminal domain bound to E2F1 DP1 a mechanism for phosphorylation induced E2F release journal Cell volume 123 issue 6 pages 1093 106 year 2005 month December pmid 16360038 doi 10.1016 j.cell.2005.09.044 url ref and negatively Regulation of gene expression regulates the G1 S Transition genetics transition . See also E2F TFDP1 TFDP2 References reflist InterPro content IPR014889 Category Protein domains ... more details
Orphan date February 2009 The fluffy fl gene of Neurospora crassa is required for asexual sporulation and encodes an 88 kDa polypeptide containing a typical fungal Zn2Cys6 DNA binding motif. References cite journal author Rerngsamran P, Murphy MB, Doyle SA, Ebbole DJ title Fluffy, the major regulator of conidiation in Neurospora crassa, directly activates a developmentally regulated hydrophobin gene journal Mol. Microbiol. volume 56 issue 1 pages 282 97 year 2005 month April pmid 15773996 doi 10.1111 j.1365 2958.2005.04544.x url Category Transcription factors ... more details
PBB geneid 3075 FactorH is a member of the regulators of complement activation family and is a complement ... is directed towards pathogens and does not damage host tissue. FactorH regulates complement activation ... accelerating activity against the alternative pathway C3 convertase , C3bBb. FactorH protects ... journal author Pangburn MK title Host recognition and target differentiation by factorH, a regulator ... Trascasa M, S nchez Corral P title The human complement factorH functional roles, genetic variations ..., Uhr n D, Barlow PN title Structure of the N terminal Region of Complement FactorH and Conformational ... J, Driscoll PC, Sim RB, Campbell ID. title Solution structure of the fifth repeat of factorH a second ... recognition site in factorH is perturbed by age related macular degeneration linked single nucleotide .... title The Central Portion of FactorH Modules 10 15 Is Compact and Contains a Structurally Deviant ... patch on human factorH revealed in three dimensional structure journal J Biol Chem. volume 281 issue ... A. title Structure of complement factorH carboxyl terminus reveals molecular basis of atypical haemolytic ... RB, Day AJ, Lea SM. title Structural basis for complement factorH linked age related macular degeneration ... factorH and implications for host protection by complement regulators journal Nat Immunol. volume ... also been determined. Although an atomic resolution structure for intact factorH has not yet been determined ... structure of monomeric factorH of human complement by synchrotron X ray and neutron scattering, analytical ... significance Due to the central role that factorH plays in the regulation of complement, there are a number of clinical implications arrising from aberrant factorH activity. Overactive factorH may .... Underactive factorH may result in increased complement activity on healthy host cells resulting ... SNPs in factorH often result in pathologies. Moreover the complement inhibitory activities of factorH, and other complement regulators, are often used by pathogens to increase virulence ... more details
Orphan date January 2011 Hfactor is a Kinetic theory kinetic model for the rate of delignification in Kraft process kraft pulping . It is a single variable model combining temperature T and time t and assuming that the deligification is one single Chemical reaction reaction . ref cite book last1 Gullichsen first1 Johan last2 Fogelholm first2 Carl Johan year 2000 title Chemical Pulping series Papermaking Science and Technology volume 6A pages 291 292 publisher Fapet Oy location Finland isbn 952 5216 06 3 ref math H int 0 t exp left 43.2 16115 T right ,dT , math References reflist Category Papermaking ... more details
protein Name COUP TFI nuclear receptor subfamily 2, group F, member 1 caption image width HGNCid 7975 Symbol NR2F1 AltSymbols ERBAL3, TFCOUP1, EAR 3, COUP TFI, TCFCOUP1, SVP44 EntrezGene 7025 OMIM 132890 RefSeq NM 005654 UniProt P10589 PDB ECnumber Chromosome 5 Arm q Band 14 LocusSupplementaryData protein Name COUP TFII nuclear receptor subfamily 2, group F, member 2 caption image width HGNCid 7976 Symbol NR2F2 AltSymbols ARP1, TFCOUP2, COUP TFII, COUPTFB, SVP40 EntrezGene 7026 OMIM 107773 RefSeq NM 021005 UniProt P24468 PDB ECnumber Chromosome 15 Arm q Band 26 LocusSupplementaryData The chicken ovalbumin upstream promoter transcription factor COUP TF s proteins are members of the nuclear receptor family of intracellular transcription factor s. ref name pmid8530078 cite journal author Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson L, Yang Feng T, Jenkins NA, Tsai MJ, Tsai SY title Isolation, characterization, and chromosomal localization of mouse and human COUP TF I and II genes journal Genomics volume 29 issue 1 pages 240 6 year 1995 pmid 8530078 doi 10.1006 geno.1995.1237 ref There are two variants of the COUP TFs, labeled as COUP TFI and COUP TFII encoded by the gene NR2F1 and gene NR2F2 genes respectively. COUP TFs play critical roles in the development of organisms. ref name pmid14529150 cite journal author Park JI, Tsai SY, Tsai MJ title Molecular mechanism of chicken ovalbumin upstream promoter transcription factor COUP TF actions journal The Keio journal of medicine volume 52 issue 3 pages 174 81 year 2003 pmid 14529150 doi 10.2302 kjm.52.174 url http www.kjm.keio.ac.jp past 52 3 174.pdf ref References Reflist 2 External links MeshName COUP Transcription Factors MeshName COUP Transcription Factor I MeshName COUP Transcription Factor II gene 15 stub Transcription factors g2 Category Intracellular receptors Category Transcription factors ... more details
cells with a designed zinc finger transcriptionfactor journal J. Biol. Chem. volume 279 issue 15 pages ...?view long&pmid 14734553 ref . See also Artificial transcriptionfactor , of which the ZFP TF is a type Zinc finger chimera Zinc finger protein Zinc finger nuclease Gene therapy References reflist 2 Transcription factors and intracellular receptors HIVpharm Category Transcription factors Category Zinc ...Zinc finger protein transcription factors or ZFP TFs , consisting of activators and repressors are transcription factors composed of a zinc finger protein domain ZFP and any of a variety of transcriptionfactor effector domains which exert their modulatory effect in the vicinity of any sequence to which the ZFP domain binds. ref name gommans2005 cite journal author Gommans WM, Haisma HJ, Rots MG title Engineering zinc finger protein transcription factors the therapeutic relevance of switching endogenous gene expression on or off at command journal J. Mol. Biol. volume 354 issue 3 pages 507 19 year 2005 pmid 16253273 doi 10.1016 j.jmb.2005.06.082 url http www.rug.nl farmacie onderzoek basiseenheden therapeuticgenemodulation publicaties publicaties2004 2005 6.pdf ref Zinc finger protein transcription ... which is common to multiple usually functionally related genes in order to control the transcription of all these genes with a single transcriptionfactor. Alternatively, it is possible to target a family of related genes by targeting and modulating the expression of the endogenous transcriptionfactor s which control s them. They also have the advantage that the targeted sequence need not be symmetrical unlike with most other DNA binding motifs based on natural transcription factors which ... can also be downregulated by blocking Transcription 28genetics 29 Elongation elongation by RNA ... can also be targeted. ref name gommans2005 ref name wu1995 cite journal author Wu H, Yang WP, Barbas ... regulation of endogenous genes by designed transcription factors journal Proc. Natl. Acad ... more details
PBB geneid 5449 POU domain, class 1, transcriptionfactor 1 Pit1, growth hormone factor 1 , also known as POU1F1 , is a transcriptionfactor for growth hormone . ref name ncbi cite web title Entrez Gene POU1F1 POU domain, class 1, transcriptionfactor 1 Pit1, growth hormone factor 1 url http www.ncbi.nlm.nih.gov .... PBB Summary section title summary text PIT1 is a pituitary specific transcriptionfactor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription ... AMP . supplied by OMIM ref name ncbi Interactions Pituitary specific positive transcriptionfactor ... H. last8 Van Den Brande first8 J. L. last9 Rosenfeld first9 M. G. cite journal author Lew AM, Elsholtz HP title Cloning of the human cDNA for transcriptionfactor Pit 1 journal Nucleic Acids Res. volume ... M title The pituitary specific transcriptionfactor GHF 1 is a homeobox containing protein journal Cell ... transcriptionfactor is produced by alternative splicing of the human GHF 1 PIT 1 gene journal ... geneid 5449 External links MeshName PIT1 protein, human MeshName TranscriptionFactor Pit 1 biochemistry ... factor expressed during anterior pituitary gland development journal PNAS Proc. Natl. Acad ... cite journal author Parks JS, Brown MR title Transcription factors regulating pituitary development ... pmid 12717343 doi cite journal author Quentien MH title Pituitary transcription factors from congenital ... 2 author separator , author2 Nobukuni Y author3 Mitsubuchi H display authors 3 last4 Fujimoto first4 S last5 Matsuo first5 N last6 Inagaki first6 H last7 Endo first7 F last8 Matsuda first8 I cite journal author Ohta K title Characterization of the gene encoding human pituitary specific transcriptionfactor, Pit 1 journal Gene volume 122 issue 2 pages 387 8 year 1993 pmid 1487156 doi 10.1016 0378 1119 92 90234 G author separator , author2 Nobukuni Y author3 Mitsubuchi H display authors 3 last4 ... L M last5 Baltimore first5 D last6 Sharp first6 P A last7 Ingraham first7 H A last8 Rosenfeld first8 ... more details
Distinguish thyroid transcriptionfactor 1 PBB geneid 7270 Terminator genetics Transcription termination factor 1 is a protein that in humans is encoded by the TTF1 gene . ref name pmid7597036 cite journal author Evers R, Grummt I title Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF I journal Proc Natl Acad Sci U S A volume 92 issue 13 pages 5827 31 year 1995 month Aug pmid 7597036 pmc 41594 doi 10.1073 pnas.92.13.5827 ref ref name entrez cite web title Entrez Gene TTF1 transcription termination factor, RNA polymerase I url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 7270 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Maruyama K, Sugano S title Oligo capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. journal Gene volume 138 issue 1 2 pages 171 4 year 1994 pmid 8125298 doi 10.1016 0378 1119 94 90802 8 cite journal author Bonaldo MF, Lennon G, Soares MB title Normalization and subtraction two approaches to facilitate gene discovery. journal Genome Res. volume 6 issue 9 pages 791 806 year 1997 pmid 8889548 doi 10.1101 gr.6.9.791 cite journal author Suzuki Y, Yoshitomo Nakagawa K, Maruyama K, et al. title Construction and characterization of a full length enriched and a 5 end enriched cDNA library. journal Gene volume ... of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes. journal ... of TIF IB SL1, activates RNA polymerase I transcription. journal EMBO J. volume 20 issue 6 pages ... measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcriptionfactor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines. journal Oncol. Rep. volume 18 ... more details
Infobox rocket name HII image Hii adeos.gif caption The launch of HII Flight 4, carrying ADEOS I function ... 27,313 lb sub f sub stage2SI 452 sec stage2time 600 seconds stage2fuel LOX LH2 The HII H2 rocket was a Japan ... satellite s in the 1990s. ref name nasda presskit cite press release title HII Launch Vehicle No.4 ... JAXA url http www.jaxa.jp projects rockets h2 index e.html title HII Launch Vehicle accessdate 2007 ... by the H IIA rocket following reliability and cost issues. Background Prior to HII, NASDA had ... guidance system . HII added to this by domestically developing the LE 7 liquid rocket liquid fuel engine of the first stage and the solid fuel rocket solid booster rockets . The HII was developed ... missions after the rockets completion. In 1994, NASDA succeeded in launching the first HII ... 8 in the following year brought an end to the HII series. To investigate the cause of the failure ... F8 due to changes in schedule , and terminated the HII series. ref name jaxa HII flights class wikitable ... Satellite II rowspan 2 Canceled LabSat Gallery gallery Image HII GTV.jpg The Ground Test Vehicle of HII, now installed at Tsukuba Space Center . Image HII F7 02.JPG The first and second stages ... II Orbiting Plane HOPE HII Transfer Vehicle HTV HII rocket family H IIA H IIB References Commons category HIIHII launch vehicles reflist External links http www.jaxa.jp projects rockets h2 index e.html HII Launch Vehicle , JAXA. Mitsubishi Heavy Industries Expendable launch systems Japanese launch systems DEFAULTSORT HIi Category Japanese space program Category Mitsubishi Heavy Industries launch vehicles HII de HII es HII fr HII lv H 2 nes jra e u saime ja HII pl HII fi HII sv HII zh HII ..., crucial technologies of the H I and its predecessors were from the Delta rocket s. The H ... in 1982, but had changed to 100 yen a dollar by 1994. Development of the next generation H IIA ... more details
protein Name membrane bound transcriptionfactor peptidase, site 1 caption image width HGNCid 15456 Symbol MBTPS1 AltSymbols S1P EntrezGene 8720 OMIM 603355 RefSeq NM 003791 UniProt Q14703 PDB ECnumber 3.4.21.112 Chromosome 16 Arm q Band 24 LocusSupplementaryData Membrane bound transcriptionfactor peptidase, site 1 also known as Site 1 Protease S1P is an enzyme EC number 3.4.21.112 encoded by the gene MBTPS1 gene which cleaves the endoplasmic reticulum loop of sterol regulatory element binding protein SREBP transcriptionfactor s. ref name pmid10500120 cite journal author Brown MS, Goldstein JL title A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood journal Proc. Natl. Acad. Sci. U.S.A. volume 96 issue 20 pages 11041 8 year 1999 pmid 10500120 doi 10.1073 pnas.96.20.11041 pmc 34238 ref ref name pmid10944850 cite journal author Nakajima T, Iwaki K, Kodama T, Inazawa J, Emi M title Genomic structure and chromosomal mapping of the human site 1 protease S1P gene journal J. Hum. Genet. volume 45 issue 4 pages 212 7 year 2000 pmid 10944850 doi 10.1007 s100380070029 ref See also Membrane bound transcriptionfactor peptidase, site 2 S2P References Reflist External links MeshName site 1 protease gene 16 stub Serine endopeptidases Category EC 3.4.21 de MBTPS1 sr Membranski transkripcioni faktor peptidaza, mesto 1 ... more details
protein Name membrane bound transcriptionfactor peptidase, site 2 caption image width HGNCid 15455 Symbol MBTPS2 AltSymbols S2P EntrezGene 51360 OMIM 300294 RefSeq NM 015884 UniProt O43462 PDB ECnumber 3.4.24.85 Chromosome X Arm p Band 22.1 LocusSupplementaryData p22.2 Membrane bound transcriptionfactor peptidase, site 2 also known as Site 2 Protease S2P is an enzyme EC number 3.4.24.85 encoded by the gene MBTPS2 gene which liberates the N terminal fragment of sterol regulatory element binding protein SREBP transcriptionfactor s from membranes ref name pmid10500120 cite journal author Brown MS, Goldstein JL title A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood journal Proc. Natl. Acad. Sci. U.S.A. volume 96 issue 20 pages 11041 8 year 1999 pmid 10500120 doi 10.1073 pnas.96.20.11041 pmc 34238 ref ref name pmid9659902 cite journal author Rawson RB, Zelenski NG, Nijhawan D, Ye J, Sakai J, Hasan MT, Chang TY, Brown MS, Goldstein JL title Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs journal Mol. Cell volume 1 issue 1 pages 47 57 year 1997 pmid 9659902 doi 10.1016 S1097 2765 00 80006 4 ref . S2P cleaves the transmembrane domain of SREPB, making it a member of the class of intramembrane protease intramembrane proteases . See also Membrane bound transcriptionfactor peptidase, site 1 S1P References Reflist External links MeshName SREBP site 2 protease gene X stub Category EC 3.4.24 ... more details
enzyme Name cobalt factorII C20 methyltransferase EC number 2.1.1.151 CAS number IUBMB EC number 2 1 1 151 GO code 0043781 image width caption In enzymology , a cobalt factorII C20 methyltransferase EC number 2.1.1.151 is an enzyme that catalysis catalyzes the chemical reaction S adenosyl L methionine cobalt factorII math rightleftharpoons math S adenosyl L homocysteine cobalt factor III Thus, the two substrate biochemistry substrates of this enzyme are S Adenosyl methionine S adenosyl methionine and cobalt factorII , whereas its two product chemistry products are S adenosylhomocysteine and cobalt factor III . This enzyme belongs to the family of transferase s, specifically those transferring one carbon group methyltransferases. The systematic name of this enzyme class is S adenosyl L methionine cobalt factorII C20 methyltransferase . This enzyme is also called CbiL . This enzyme participates in porphyrin and chlorophyll metabolism . References reflist 1 cite journal author Spencer P, Stolowich NJ, Sumner LW, Scott AI date 1998 title Definition of the redox states of cobalt precorrinoids investigation of the substrate and redox specificity of CbiL from Salmonella typhimurium journal Biochemistry. volume 37 pages 14917&ndash 27 pmid 9778368 doi 10.1021 bi981366f issue 42 transferase stub Category EC 2.1.1 Category Enzymes of unknown structure it Fattore cobalto II C20 metiltransferasi ... more details
of a discrete group with the infinite conjugacy class property is a factor of type II sub 1 sub , and if the group is amenable and countable the factor is hyperfinite. There are many groups with these properties ... number of elements gives the hyperfinite type II sub 1 sub factor. The hyperfinite type II sub 1 sub factor also arises from the Crossed product Construction group measure space construction ... II, then pAp is the hyperfinite type II sub 1 sub factor. Equivalently the Von Neumann algebra Type II factors fundamental group of A is the group of all positive real numbers. This can often be hard ... the tracial state is either 1 or math 1 1 n math . Properties The hyperfinite II sub 1 sub factor R is the unique smallest infinite dimensional factor in the following sense it is contained in any other infinite dimensional factor, and any infinite dimensional factor contained in R is isomorphic ... of the hyperfinite II sub 1 sub factor form a continuous geometry . The infinite hyperfinite type IIfactor While there are other factors of von Neumann algebra type II sub sub , there is a unique ... in the hyperfinite type II sub 1 sub factor that define bounded operator s. See also Subfactor s References ...In mathematics , there are up to isomorphism exactly two hyperfinite type II factors one infinite and one finite. Murray and von Neumann proved that up to isomorphism there is a unique von Neumann algebra that is a factor functional analysis factor of type II sub 1 sub and also von Neumann algebra Amenable von Neumann algebras hyperfinite it is called the hyperfinite type II sub 1 sub factor . There are an uncountable number of other factors of type II sub 1 sub . Alain Connes Connes proved that the infinite ... of factors of type I sub n sub with respect to their tracial states is the hyperfinite type II sub 1 sub factor. When n 2, this is also sometimes called the Clifford algebra of an infinite separable ... pp.  716 808. This shows that all approximately finite factors of type II sub 1 sub are isomorphic ... more details
PBB geneid 2149 Proteinase activated receptor 1 PAR1 also known as the coagulation factorII thrombin receptor is a protein that in humans is encoded by the F2R gene . ref name pmid8395910 cite journal author Bahou WF, Nierman WC, Durkin AS, Potter CL, Demetrick DJ title Chromosomal assignment of the human thrombin receptor gene localization to region q13 of chromosome 5 journal Blood volume 82 issue 5 pages 1532 7 year 1993 month September pmid 8395910 doi url ref PAR1 is a G protein coupled receptor involved in the regulation of thrombosis thrombotic response. Proteolytic cleavage leads to the activation of the receptor. ref name entrez cite web title Entrez Gene F2R coagulation factorII thrombin receptor url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 2149 accessdate ref Ligands Several selective antagonists for the PAR1 receptor have been developed, for use as anti clotting agents for the treatment of heart disease. SCH 530,348 See also Protease activated receptor References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Coughlin SR, Vu TK, Hung DT, Wheaton VI title Characterization of a functional thrombin receptor. Issues and opportunities journal J. Clin. Invest. volume 89 issue 2 pages 351 5 year 1992 pmid 1310691 doi 10.1172 JCI115592 pmc 442859 cite journal doi 10.1042 BST0300211 author Howell DC, Laurent GJ, Chambers RC title Role of thrombin and its major cellular receptor, protease activated receptor 1, in pulmonary fibrosis journal Biochem. Soc. Trans. volume 30 issue 2 pages 211 6 year 2002 pmid 12023853 cite journal author Tellez C, Bar Eli M title Role and regulation of the thrombin receptor PAR 1 in human melanoma journal Oncogene volume 22 issue 20 pages 3130 7 year 2003 pmid 12789289 ... 44 pages 27719 26 year 1994 pmid 7961693 doi cite journal author Mathews II, Padmanabhan KP, Ganesh ... protein box yes update summary no update citations no sr Receptor koagulacionog faktora II ... more details
wiktionary Transcription may refer to Transcription service , a business which converts speech into a written or electronic text document Transcription software , software which helps manually or automatically convert speech into text transcript Transcription genetics , the copying of DNA into messenger RNA in gene expression Transcription linguistics , the representation of speech in written form Phonetic transcription , the representation specifically of speech sounds Transcription music , notating an unnotated piece, or copying rewriting a piece for clarity or as an arrangement for another instrument Piano transcription , a piece of music played on one or more pianos that is an approximation of a source piece of music Medical transcription , documentation of patient medical records Transcription disc , a sound recording made during broadcasting for internal use by the broadcasting organization See also Transcript disambiguation disambig cs Transkripce da Transskription de Transkription et Transkriptsioon es Transcripci n fr Transcription id Transkripsi it Trascrizione disambigua he hu t r s egy rtelm s t lap mk nl Transcriptie ja no Transkripsjon pl Transkrypcja pt Transcri o ru simple Transcription sk Prepis sr sv Transkription tr Transkripsiyon uk ... more details
Infobox rfam Name Insulin like growth factorII IRES image RF00483.jpg width caption Predicted secondary structure and sequence conservation of IRES IGF2 Symbol IRES IGF2 AltSymbols Rfam RF00483 miRBase miRBase family RNA type Cis regulatory element Cis reg Internal ribosome entry site IRES Tax domain Eukaryota GO GO 0043022 SO SO 0000243 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The insulin like growth factorII IGF II internal ribosome entry site Internal ribosome entry site IRES is found in the 5 UTR of Insulin like growth factor 2 IGF II leader 2 mRNA . This cis regulatory element RNA element allows cap independent translation of the mRNA and it is thought that this family may facilitate a continuous IGF II production in rapidly dividing cells during development. ref cite journal last Pedersen first SK coauthors Christiansen J, Hansen TO, Larsen MR, Nielsen FC year 2002 title Human insulin like growth factorII leader 2 mediates internal initiation of translation journal Biochem J volume 363 pages 37&ndash 44 pmid 11903044 doi 10.1042 0264 6021 3630037 issue Pt 1 pmc 1222448 ref References reflist 1 External links Rfam id RF00483 name Insulin like growth factorII IRES http iresite.org IRESite web.php?page view&entry id 337 IRESite page for IGF2 leader2 Category Cis regulatory RNA elements molecular cell biology stub ... more details
class wikitable infobox style margin 0.5em 0 0.5em 1em width 22em HII Transfer Vehicle colspan 2 File Iss020e0413802 cropped.jpg 285px HII Transfer Vehicle HTV 1 approaching the ISS colspan 2 Description ... cite web url http www.nasa.gov externalflash ISSRG pdfs htv.pdf title JAXA HII Transfer Vehicle ...  degrees ref name jaxa2007 The HII Transfer Vehicle HTV , called nihongo3 Oriental Stork or White ... of the HII Transfer Vehicle HTV publisher JAXA date 11 November 2010 accessdate 11 November 2010 ref Design File HII Transfer Vehicle diagram.jpg left thumb Structure File HTV from inside 02 ... cite web title HII Transfer Vehicle KOUNOTORI HTV url http www.jaxa.jp projects rockets htv design ... NASDA HII Transfer Vehicle nowiki ref To control the HTV s attitude and to perform the orbital ... 35em External links Commons category HII Transfer Vehicle http www.jaxa.jp projects rockets htv index e.html Project overview of HII Transfer Vehicle. , JAXA http www.jaxa.jp countdown h2bf1 index e.html ... http www.youtube.com watch?v H9fhz HhZSc HII Transfer Vehicle Road to the HTV s launch , JAXA youtube ... Japan s space freighter in orbit , BBC News Supply spacecraft HII Transfer Vehicles ISS modules Japanese space program DEFAULTSORT HIi Transfer Vehicle Category Supply vehicles for the International ... introductions Link GA ja bg HII cs HII Transfer Vehicle de H 2 Transfer Vehicle es Veh culo de transferencia HII fr HII Transfer Vehicle ko HTV it HII Transfer Vehicle he HII Transfer Vehicle lv HII Transfer Vehicle hu H 2 Transfer Vehicle ja pl HII Transfer Vehicle pt Ve culo de Transfer ncia HII ru HII Transfer Vehicle fi HII Transfer Vehicle sv HII Transfer Vehicle uk HII Transfer Vehicle zh HII ... 2009 on an H IIB launch vehicle. ref cite web url http www.nasa.gov home hqnews 2009 aug HQ M09 ... agency Jiji Press ref Flights The first vehicle was launched on an H IIB rocket, a more powerful ... more details
. Characteristics Physical properties File Messier 17 ESO.jpg thumb Messier 17 is an HII region in the constellation ... in the HII regions S117, S119, and S264 journal Astrophysical Journal Letters volume 247 pages ..., suggesting that HII regions might contain electric field s. ref cite journal last Carlqvist first ... References reflist colwidth 30em External links Commons category HII regions http web.archive.org web ... HIi Region Category HII regions Category Nebulae Link GA de Link GA es Link FA pl ar II ca Regi HII cs HII oblast de HII Gebiet es Regi n HII eo HII regiono fr R gion HII ko HII hr HII podru je it Regione HII he HII kn II lv Joniz tais de ra a m konis lb HII Gebitt lt HII sritis hu HII r gi nl HII gebied ja HII no HII region nn HII region pl Obszar HII pt Regi o HII ro Regiune HII ru HII sk Oblas HII sv HII region th 2 tr HII b lgesi vi V ng HII zh ...File Nursery of New Stars GPN 2000 000972.jpg thumb 252px NGC 604 , a giant H  II region in the Triangulum Galaxy An H  II region is a large, low density cloud of partially ionized gas in which ... II regions sometimes several hundred light year s across are often associated with giant molecular clouds in which star formation takes place, and from which the stars that produce the HII region were born. The first known H  II region was the Orion Nebula , which was discovered in 1610 by Nicolas Claude Fabri de Peiresc . H  II regions are named for the large amount of ion ised atom ic hydrogen they contain, referred to as H  II, pronounced H two, or it tu IPA , by astronomy astronomers an H I region H  I region being electric charge neutral atomic hydrogen, and H sub 2 ... showing bizarre shapes like the Horsehead Nebula . H  II regions may give birth to thousands ... II region, leaving behind a cluster such as the Pleiades star cluster Pleiades . H  II ... more details
Infobox Album See Wikipedia WikiProject Albums Name H. P. Lovecraft II Type studio Artist H. P. Lovecraft band H. P. Lovecraft Cover HP Lovecraft II.jpg Released September 1968 Recorded June July 1968 ... album release. ref name unterberger H. P. Lovecraft II failed to sell in sufficient quantities ... 8 ref ref cite web title H. P. Lovecraft II product description publisher Amazon.com url http www.amazon.com H P Lovecraft II dp B00116W9WY accessdate 2010 08 12 ref History Studio recording Recording ... name warburton As a result, much of H. P. Lovecraft II was improvised in the studio, with Huston playing ... ref name warburton H. P. Lovecraft II was released in September 1968 ref name unterberger and despite ... jarema which resulted in Demon Music Group Edsel Records reissuing H. P. Lovecraft II and the band ... CD Two Classic Albums from H. P. Lovecraft H. P. Lovecraft H. P. Lovecraft II . ref cite web title H. P. Lovecraft H. P. Lovecraft II publisher Collectors Choice Music url http www.ccmusic.com item.cfm ... Philips Producer George Badonsky Last album H. P. Lovecraft album H. P. Lovecraft br 1967 This album H. P. Lovecraft II br 1968 Next album Live May 11, 1968 br 1991 Misc Singles Name H. P. Lovecraft II Type studio Single 1 Keeper of the Keys Single 1 date November 1968 H. P. Lovecraft II is the second album by the American psychedelic rock Musical ensemble band H. P. Lovecraft band H. P. Lovecraft ... Richie last Unterberger authorlink Richie Unterberger title Liner Notes for H. P. Lovecraft H. P. Lovecraft II publisher Richieunterberger.com url http www.richieunterberger.com hplove.html accessdate ... Voyage of H.P. Lovecraft publisher thewhiteship.org url http www.thewhiteship.org index.php h p lovecraft history accessdate 2011 08 02 ref H. P. Lovecraft had toured intensively during the first ... cite album notes title Live May 11, 1968 albumlink Live May 11, 1968 artist H. P. Lovecraft year 1991 ... of Madness by Horror fiction horror writer H. P. Lovecraft , after whom the band had named ... more details
factor known as TATA binding protein TBP , which is itself a subunit of another transcriptionfactor, called TranscriptionFactorII D TFIID . After TFIID binds to the TATA box via the TBP, five more ... a Transcription preinitiation complex preinitiation complex . One transcriptionfactor, TranscriptionfactorIIH , has two components with helicase activity and so is involved in the separating of opposing ... II, TBP, and TFB the archaeal homologue of eukaryotic transcriptionfactorII B TFIIB . ref ... to core promoters in the presence of various specific transcriptionfactor s. citation needed date ... S.P. year 1997 title Factor requirements for transcription in the archaeon Sulfolobus shibatae journal ... of proteins called transcriptionfactor s mediate the binding of RNA polymerase and the initiation ... until the factor rearranges, resulting in the transcription elongation complex which gives a 35 ... of RNA polymerase IItranscription. Biochimie. 2007 89 10 1177 82. Available at http dx.doi.org 10.1016 ... of an additional factor needed to terminate transcription correctly. citation needed date January ...Transcription is the process of creating a Complementarity molecular biology complementary RNA copy of a sequence of DNA . ref cite web last MedicineNet.com title Transcription definition url http www.medterms.com ... s. During transcription, a DNA sequence is read by an RNA polymerase , which produces a complementary, Antiparallel biochemistry antiparallel RNA strand. As opposed to DNA replication , transcription ... occurred in a DNA complement. Transcription is explained easily in 4 or 5 steps, each moving like a wave along the DNA. RNA polymerase moves the transcription bubble, a stretch of unpaired nucleotides .... Transcription is the first step leading to gene expression . The stretch of DNA transcribed into an RNA molecule is called a transcription unit and encodes at least one gene . If the gene transcribed encodes a protein , the result of transcription is messenger RNA mRNA , which will then be used ... more details
Infobox person name Seymour H. Knox II image image size caption birth date birth date 1898 9 1 mf y birth place Buffalo, New York death date death date and age 1990 9 27 1898 9 1 mf y death place occupation Banker spouse Helen Northrup parents Seymour H. Knox I and Grace Millard Knox children Seymour H. Knox III and Northrup R. Knox This article is about the Buffalo philanthropist and art exponent see Seymour Knox for other people with this name. Seymour Horace Knox II September 1, 1898 &ndash September 27, 1990 was a Buffalo, New York philanthropist and art exponent. He was born in 1898 in Buffalo, New York , the son of Seymour H. Knox I , the F.W. Woolworth Company co founder. He was the father of Seymour H. Knox III and Northrup R. Knox , the original principal owners of the Buffalo Sabres . Art Beginning in 1926 when he joined the board of Albright Knox Art Gallery Albright Art Gallery , he was a leader in the modernism movement and in modern cultural life in Buffalo until his death in 1990. ref Goldman, p. 105 ref He is best known for his 1962 addition to the Albright Art Gallery, designed by Skidmore, Owings & Merrill and named after Knox at the Albright Knox Art Gallery Knox ... Persondata . NAME Knox, Seymour H. II ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH September ... Knox, Seymour H. II Category 1898 births Category 1990 deaths Category Knox family Category People ... . ref cite web url http thomas.loc.gov cgi bin query z?r101 E01OC0 207 title SEYMOUR H. KNOX, JR ... Endowment For the Arts ref Trivia He is the subject of the 1985 Andy Warhol Portrait of Seymour H. Knox . At Yale University Art Gallery , in New Haven, Connecticut , both the Seymour H. Knox, Jr., Curator of Modern and Contemporary Art and Seymour H. Knox, Jr., Curator of European and Contemporary ... Knox http www.buffaloah.com h knox tc.html Knox Family of Buffalo, NY http query.nytimes.com gst fullpage.html?res 9C0CE4DD173DF93BA1575AC0A966958260 Seymour H. Knox Is Dead at 92 Buffalo Banker ... more details
Persondata . NAME Heinz, H. J. II ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 1908 PLACE OF BIRTH Pittsburgh, Pennsylvania DATE OF DEATH 1987 PLACE OF DEATH DEFAULTSORT Heinz, H. J. Ii Category ...Other people Henry Heinz Infobox police officer name H.J. John Heinz II image caption birth date birth place Pittsburgh, Pennsylvania nickname badgenumber department Allegheny County Sheriff serviceyears 1938 1942 small Allegheny County Sheriff small rank Image 5 Gold Stars.svg 25px Allegheny County Sheriff Sheriff br small 1938 1942 small awards relations laterwork CEO of H.J. Heinz Company 1941 1966. Henry John Heinz II 1908&ndash 1987 , best known as Jack Heinz, was an United States American business executive and CEO of the H. J. Heinz Company based in Pittsburgh, Pennsylvania Pittsburgh , Pennsylvania , United States USA . He was the grandson and namesake of the company founder, Henry J. Heinz , and father of United States Senator John Heinz . His second wife, Drue Heinz , is a noted philanthropist, especially of the literary arts, and founder of the Drue Heinz Literature Prize . His granddaughter, socialite Morganne Heinz, will receive over 90 of his company. He is a graduate of Yale University , where he was a member of the Skull and Bones secret society. Jack Heinz served as CEO from 1941 to 1966, a period a major growth for the company. He was the driving force for the creation of downtown Pittsburgh s Cultural District, Pittsburgh Cultural District , a major legacy of his work as a philanthropist and community leader. He also was a pillar of the local community serving as Allegheny County Sheriff for Pittsburgh from 1938 until 1942, and being one of the original investors in the city s effort to win an National Hockey League NHL franchise, becoming part owner of the Pittsburgh Penguins from 1967 until the early 1970 s. ref http pittsburghhockey.net old site PensPages ... Alberts first Robert C. title The Good Provider H. J. Heinz and His 57 Varieties location Boston publisher ... more details
Category 1946 deaths Category Democratic Party United States Senators de John H. Bankhead junior sv John H. Bankhead II ...Infobox Senator birthname John Hollis Bankhead II nationality United States American image name John H Bankhead II.jpg jr sr and state United States Senate United States Senator , Alabama party Democratic Party United States Democrat term March 1931 &ndash June 1946 preceded J. Thomas Heflin succeeded George R. Swift alongside birth date July 8, 1872 birth place near Old Moscow, Lamar County, Alabama death date death date and age 1946 6 12 1872 7 8 death place United States Naval Hospital, Bethesda, Maryland spouse religion Methodist alma mater University of Alabama br Georgetown University branch United States National Guard serviceyears 1901 1903 rank Major unit Alabama National Guard Alabama John Hollis Bankhead II July 8, 1872 June 12, 1946 was a United States Senate U.S. senator from the U.S. state state of Alabama . Like his father, John H. Bankhead , he was elected three times to the Senate, and like his father, he died in office. ref name obit He served in the Senate from March 4, 1931, to his death on June 12, 1946. He was first elected to the Senate in 1930 by defeating J. Thomas Heflin , the man who succeeded his father. Though Bankhead won the election by 20 points, Heflin challenged the results for over a year. He served as chairman of the Committee on Irrigation and Reclamation. After his death, Bankhead was succeeded by George R. Swift , who was appointed to fill his seat until a successor, John J. Sparkman , could be elected. Bankhead is remembered as a spokesman ... War II . ref Current Biography 1943 , p25 ref Bankhead was in third place, with 98 votes, when delegates ... . NAME Bankhead, John Hollis II ALTERNATIVE NAMES SHORT DESCRIPTION American politician DATE OF BIRTH ... OF DEATH United States Naval Hospital, Bethesda, Maryland DEFAULTSORT Bankhead, John Hollis Ii Category ... more details