Hazards Solubility MainHazards FlashPt Autoignition Uridinediphosphateglucose uracil diphosphateglucose , Uridinediphosphate UDP glucose is a nucleotide sugar . It is involved in glycosyltransferase ... Uracil Uridinediphosphate TDP glucose Nucleotide sugars Fructose and galactose metabolic intermediates ... of glucose as a substrate for enzymes called glucosyltransferase s. ref cite journal author Rademacher ... by the enzymes that make polysaccharide s containing galactose and glucuronic acid . UDP glucose can ... glucose consists of the pyrophosphate Functional group group , the pentose sugar ribose , glucose ... more details
Unreferenced stub auto yes date December 2009 Chembox Verifiedfields changed verifiedrevid 470620324 ImageFile Uridindiphosphat protoniert.svg ImageSize IUPACName Uridine 5 trihydrogen diphosphate OtherNames Section1 Chembox Identifiers CASNo 58 98 0 CASNo Ref cascite correct CAS PubChem 1158 ChEMBL Ref ebicite changed EBI ChEMBL 130266 IUPHAR ligand 1749 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 19952429 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H12N2O6.2H3O4P c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 2 1 5 2,3 4 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 2 H3,1,2,3,4 t4 ,6 ,7 ,8 m1.. s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey PMPFLUWUGZHTOK WFIJOQBCSA N SMILES MeSHName Uridine diphosphate Section2 Chembox Properties Formula C sub 9 sub H sub 14 sub N sub 2 sub O sub 12 sub P sub 2 sub MolarMass 404.161 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine diphosphate , abbreviated UDP , is a nucleoside diphosphate . It is an ester of pyrophosphoric acid with the nucleoside uridine . UDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase uracil . See also Nucleoside Nucleotide DNA RNA Oligonucleotide UGGT Nucleobases, nucleosides, and nucleotides DEFAULTSORT Uridine Diphosphate Category Nucleotides Category Pyrimidinediones Biochem stub ca Difosfat d uridina da Uridindifosfat de Uridindiphosphat es Uridina difosfato fa fr Uridine diphosphate gl Urid n difosfato it Uridina difosfato nl Uridinedifosfaat ja pl Urydyno 5 difosforan sr Uridin difosfat fi Uridiinidifosfaatti zh ... more details
DISPLAYTITLE Uridinediphosphate N acetylglucosamine Chembox verifiedrevid 399168372 Name Uridinediphosphate N acetylglucosamine ImageFile UDP N acetylglucosamine.png ImageSize 200px IUPACName 2 R ,3 R ,4 R ,5 S ,6 R 3 acetamido 4,5 dihydroxy 6 hydroxymethyl oxan 2 yl nowiki nowiki 2 R ,3 S ,4 R ,5 R 5 2,4 dioxopyrimidin 1 yl 3,4 dihydroxyoxolan 2 yl methoxy hydroxyphosphoryl hydrogen phosphate OtherNames UDP N acetylglucosamine UDP GlcNAc Section1 Chembox Identifiers CASNo 7277 98 7 PubChem 445675 SMILES CC O N C H 1 C H C H C H O C H 1OP O O OP O O OC C H 2 C H C H C H O2 N3C CC O NC3 O O O CO O O Section2 Chembox Properties C 17 H 27 N 3 O 17 P 2 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridinediphosphate N acetylglucosamine or UDP GlcNAc is a nucleotide sugar and a coenzyme in metabolism . It is used by glycosyltransferase s to transfer N Acetylglucosamine N acetylglucosamine residues to substrates. small D small Glucosamine is made naturally in the form of glucosamine 6 phosphate, and is the biochemical precursor of all amino sugar nitrogen containing sugars . ref cite journal doi 10.1074 jbc.R100053200 last1 Roseman first1 S title Reflections on glycobiology url http www.jbc.org cgi content full 276 45 41527 journal The Journal of Biological Chemistry volume 276 issue 45 pages 41527 42 year 2001 pmid 11553646 ref To be specific, glucosamine 6 phosphate is synthesized from fructose 6 phosphate and glutamine ref cite journal author1 Sudhamoy Ghosh last2 Blumenthal first2 HJ last3 Davidson first3 E last4 Roseman first4 S title Glucosamine Metabolism url http www.jbc.org cgi reprint 235 5 1265 journal Journal of Biological Chemistry volume 235 issue 5 pages 1265 date 1960 05 01 pmid 13827775 ref as the first step of the hexosamine biosynthesis pathway. ref http www.chem.qmul.ac.uk iubmb enzyme reaction ..., and UDP GlcNAc is thought to be part of the glucose sensing mechanism. There is also evidence that it plays ... more details
chembox verifiedrevid 402840353 ImageFile UDP glucuronic acid.png ImageSize 200px IUPACName OtherNames Section1 Chembox Identifiers InChI 1 C9H12N2O6.C6H12O13P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 2 18 20 12,13 14 5 19 21 15,16 17 3 8 4 9 6 10 11 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 1 5,8 9H, H,10,11 H2,12,13,14 H2,15,16,17 p 4 t4 ,6 ,7 ,8 2 ,3 ,4 ,5 m10 s1 InChIKey GIFKDHYZEJQSDD DNQFPBLIBB StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H12N2O6.C6H12O13P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 2 18 20 12,13 14 5 19 21 15,16 17 3 8 4 9 6 10 11 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 1 5,8 9H, H,10,11 H2,12,13,14 H2,15,16,17 p 4 t4 ,6 ,7 ,8 2 ,3 ,4 ,5 m10 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey GIFKDHYZEJQSDD BZYIUNRFSA J CASNo 2616 64 0 PubChem 17473 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 19951236 IUPHAR ligand 1784 SMILES OC O C H O C H O C H OP O O O C H C O OP O O O.O C 1NC O N C C 1 C H 2O C H CO C H O C H 2O MeSHName UDP glucuronic acid Section2 Chembox Properties Formula C sub 15 sub H sub 22 sub N sub 2 sub O sub 18 sub P sub 2 sub MolarMass 580.285 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition UDP glucuronic acid is a sugar used in the creation of polysaccharide s and is an intermediate in the biosynthesis of ascorbic acid except in primate s and guinea pig s . It is made from UDP glucose by UDP glucose 6 dehydrogenase EC 1.1.1.22 using NAD as a cofactor. It is the source of the glucuronosyl group in glucuronosyltransferase reactions. See also glucuronic acid Uridine diphosphate UDP Nucleotide sugars Category Organophosphates Category Glycosides Category Coenzymes Category Nucleotides biochem stub fa ja pl Kwas urydyno 5 difosfo D glukuronowy fi UDP glukuronihappo ... more details
chembox Verifiedfields changed verifiedrevid 476997454 ImageFile UDP Galactose.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers InChI 1 C9H12N2O6.C6H14O12P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 3 9 5 10 6 18 20 14,15 16 4 2 8 17 19 11,12 13 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 2 7,9 10H,1H2, H2,11,12,13 H2,14,15,16 p 4 t4 ,6 ,7 ,8 3 ,4 ,5 ,6 m11 s1 InChIKey UYLAOKYVSPTOGT HUYLZDLQBS StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H12N2O6.C6H14O12P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 3 9 5 10 6 18 20 14,15 16 4 2 8 17 19 11,12 13 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 2 7,9 10H,1H2, H2,11,12,13 H2,14,15,16 p 4 t4 ,6 ,7 ,8 3 ,4 ,5 ,6 m11 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey UYLAOKYVSPTOGT UESRDHDISA J CASNo Ref cascite changed ?? CASNo 2956 16 3 PubChem 1166 ChEMBL Ref ebicite changed EBI ChEMBL 1743884 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 19951534 SMILES OC C H O C H O C H OP O O O C H C O OP O O O.O C 1NC O N C C 1 C H 2O C H CO C H O C H 2O MeSHName Uridine diphosphate galactose Section2 Chembox Properties Formula C sub 15 sub H sub 24 sub N sub 2 sub O sub 17 sub P sub 2 sub MolarMass 566.302 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine diphosphate galactose Uridine diphosphate UDP galactose is an intermediate in the production of polysaccharide s. It is important in nucleotide sugars metabolism , and is the substrate for the transferase B4GALT5 . See also UDP galactose epimerase uridine diphosphate galactose Category Coenzymes Category Nucleotides biochem stub Fructose and galactose metabolic intermediates fa ja ... more details
Autoignition Thymidine diphosphateglucose often abbreviated dTDP glucose or TDP glucose is a nucleotide linked sugar consisting of thymidine diphosphate deoxythymidine diphosphate linked to glucose ...Chembox Verifiedfields changed verifiedrevid 477863841 ImageFile Thymidine diphosphate glucose.png ImageSize 200px IUPACName nowiki nowiki 2 R ,3 S ,5 R 3 hydroxy 5 5 methyl 2,4 dioxopyrimidin 1 yl oxolan 2 yl methoxy oxidophosphoryl 2 R ,3 R ,4 S ,5 S ,6 R 3,4,5 trihydroxy 6 hydroxymethyl oxan 2 yl hydrogen phosphate OtherNames TDP glucose dTDP glucose Section1 Chembox Identifiers CASNo Ref cascite changed ?? CASNo 2196 62 5 ChEMBL Ref ebicite correct EBI ChEMBL 412989 PubChem 25202390 ChEBI Ref ebicite correct EBI ChEBI 15700 SMILES CC1 CN C O NC1 O C H 2C C H C H O2 COP O O OP O O O C H 3 C H C H C H C H O3 CO O O O O ChEMBL Ref ebicite correct EBI ChEMBL 412989 PubChem 443210 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 391476 ChEBI Ref ebicite correct EBI ChEBI 15700 SMILES O C1 C C N C O N1 C H 2O C H C H O C2 COP O O OP O O O C H 3O C H C H O C H O C H 3O CO C StdInChI Ref stdinchicite correct chemspider StdInChI 1S C16H26N2O16P2 c1 6 3 18 16 25 17 14 6 24 10 2 7 20 9 31 10 5 30 35 26,27 34 36 28,29 33 15 13 23 12 22 11 21 8 4 19 32 15 h3,7 13,15,19 23H,2,4 5H2,1H3 ... pages 701 754 year 2002 pmid 12045109 ref Biosynthesis DTDP glucose is produced by the enzyme glucose 1 phosphate thymidylyltransferase and is synthesized from dTTP and glucose 1 phosphate . Pyrophosphate is a byproduct of the reaction. Uses within the cell DTDP glucose goes on to form a variety of compounds in nucleotide sugars metabolism . Many bacteria utilize dTDP glucose to form exotic sugars ... . During the syntheses of many of these exotic sugars, dTDP glucose undergoes a combined oxidation reduction reaction via the enzyme dTDP glucose 4,6 dehydratase , producing dTDP 4 keto 6 deoxy glucose. ref name Liu ref name Reeves cite journal author Samuel G, Reeves P title Biosynthesis of O ... more details
Chembox Verifiedfields changed Watchedfields changed verifiedrevid 400127872 ImageFile Cytidine diphosphate glucose.png ImageSize 200px IUPACName nowiki nowiki 2 R ,3 S ,4 R ,5 R 5 4 amino 2 oxopyrimidin 1 yl 3,4 dihydroxyoxolan 2 yl methoxy hydroxyphosphoryl 2 R ,3 R ,4 S ,5 S ,6 R 3,4,5 trihydroxy 6 hydroxymethyl oxan 2 yl hydrogen phosphate OtherNames CDP glucose Section1 Chembox Identifiers CASNo Ref cascite correct ?? CASNo 2906 23 2 PubChem 439244 SMILES C1 CN C O N C1N C H 2 C H C H C H O2 COP O O OP O O O C H 3 C H C H C H C H O3 CO O O O O O ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID 388381 SMILES O P O C H 1O C H C H O C H O C H 1O CO O OP O O OC C H 3O C H N2 C C C N C2 O N C H O C H 3O StdInChI Ref stdinchicite changed chemspider StdInChI 1S C15H25N3O16P2 c16 7 1 2 18 15 25 17 7 13 11 23 9 21 6 31 13 4 30 35 26,27 34 36 28,29 33 14 12 24 10 22 8 20 5 3 19 32 14 h1 2,5 6,8 14,19 24H,3 4H2, H,26,27 H,28,29 H2,16,17,25 t5 ,6 ,8 ,9 ,10 ,11 ,12 ,13 ,14 m1 s1 StdInChIKey Ref stdinchicite changed chemspider StdInChIKey CGPHZDRCVSLMCF JZMIEXBBSA N Section2 Chembox Properties C 15 H 25 N 3 O 16 P 2 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Cytidine diphosphateglucose , often abbreviated CDP glucose , is a nucleotide linked sugar consisting of cytidine diphospahte and glucose. ref name Reeves cite journal author Samuel G, Reeves P title Biosynthesis of O antigens genes and pathways involved in nucleotide sugar precursor synthesis and O antigen assembly journal Carbohydr. Res. volume 338 issue 23 pages 2503 19 year 2003 pmid 14670712 doi 10.1016 j.carres.2003.07.009 ref ref name Liu cite journal doi 10.1146 annurev.biochem.71.110601.135339 author Xue M. He and Hung wen Liu title Formation ... 71 issue pages 701 754 year 2002 pmid 12045109 ref Biosynthesis CDP glucose is produced from cytidine triphosphate CTP and glucose 1 phosphate by the enzyme glucose 1 phosphate cytidylyltransferase ... more details
uridine Section1 Chembox Identifiers CASNo 58 96 8 CASNo Ref cascite correct CAS PubChem ChEMBL ... Uridine Section2 Chembox Properties C 9 H 12 N 2 O 6 MolarMass 244.20 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine is a molecule ... as a deoxyuridine . Dietary sources of uridineUridine is one of the four basic components of ribonucleic ... containing RNA, uridine is released from RNA and is absorbed intact in the gut. Some food sources of uridine are Sugarcane extract ref http www.thebody.com content art30244.html Thebody.com ref Tomatoes 0.5 to 1.0 g uridine per kilogram dry weight ref http www.aseanfood.info Articles 11018411.pdf Aseanfood.info ref Brewer s yeast 3 uridine by dry weight ref name pmid11786646 cite journal author ... of beer on the plasma concentrations of uridine and purine bases journal Metab Clin Exp volume 51 .... Moderate consumption of yeast, about 5 grams per day, should provide adequate uridine for improved ... of uridine and EPA DHA omega 3 fatty acids has antidepressant activity equivalent to that of commonly ... like effects of uridine and omega 3 fatty acids are potentiated by combined treatment in rats journal ... j.biopsych.2004.11.038 url ref Uridine in the Glycolysis Pathway Uridine plays a role in the glycolysis ... to glucose and metabolized in the common glucose pathway. Once the incoming galactose has been converted into galactose 1 phosphate Gal 1 P , it is involved in a reaction with UDP glucose, a glucose molecule bonded to a UDP uridine di phosphate molecule. This process is catalyzed by the enzyme ... result is a UDP galactose molecule and a glucose 1 phosphate molecule. This process is continued to allow ... Ribosides bg ca Uridina cs Uridin de Uridin es Uridina fa fr Uridine gl Uridina it Uridina lt Uridinas nl Uridine ja oc Uridina pl Urydyna pt Uridina sr Uridin sv Uridin zh ... more details
about the naturally occurring small D small form of glucose the small L small form L Glucose Chembox Verifiedfields changed verifiedrevid 480476804 Name small D small glucose ImageFile1 Glucose chain structure.svg ImageSize1 180 ImageCaption1 ImageFile2 D glucose chain 3D balls.png ImageSize2 180 ImageCaption2 PIN D glucose SystematicName 2 R ,3 S ,4 R ,5 R 2,3,4,5,6 Pentahydroxyhexanal OtherNames Blood sugar br Dextrose br Corn sugar br small D small Glucose br Grape sugar Section1 Chembox Identifiers ... Glucose ChEBI Ref ebicite correct EBI ChEBI 4167 KEGG Ref keggcite changed kegg KEGG C00031 ... sub O sub 6 sub MolarMass 180.16 g mol ExactMass 180.063388 MeltingPt small D small glucose 146 C br small D small glucose 150 C Density 1.54 g cm sup 3 sup Solubility 91 g 100 ... capacity measurements and thermodynamic functions of crystalline D glucose at temperatures from ... icsc icsc eics0865.htm ICSC 0865 EUIndex not listed This article is about D glucose or dextrose, as noted in the hatnote at the top. The article is NOT about the term Glucose or its denotations. Keep the intro simple. Glucose IPAc en l u k o s or IPAc en k o z C sub 6 sub H sub 12 sub O sub 6 sub , also known as small D small glucose , dextrose , or grape sugar is a simple sugar monosaccharide .... Glucose is one of the main products of photosynthesis and fuels for cellular respiration . Glucose ..., those derived from the Chirality chemistry By configuration D and L right handed form of glucose, denoted small D small glucose. small D small glucose is often referred to as dextrose. The term dextrose is derived from dextrorotatory glucose . ref citation contribution dextrose url http www.m w.com ... of small D small glucose. The other stereoisomer, called L glucose small L small glucose , is hardly ever found in nature. The name glucose comes from the Greek language Greek word glukus ... Glucose metabolism.svg thumb Glucose metabolism and various forms of it in the process. br Glucose ... more details
enzyme Name uridine kinase EC number 2.7.1.48 CAS number 9026 39 5 IUBMB EC number 2 7 1 48 GO code 0004849 image width caption In enzymology , an uridine kinase EC number 2.7.1.48 is an enzyme that catalysis catalyzes the chemical reaction ATP uridine math rightleftharpoons math ADP UMP Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and uridine , whereas its two product chemistry products are adenosine diphosphate ADP and uridine monophosphate UMP . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP uridine 5 phosphotransferase . Other names in common use include pyrimidine ribonucleoside kinase , uridine cytidine kinase , uridine kinase phosphorylating , and uridine phosphokinase . This enzyme participates in pyrimidine metabolism . Structural studies As of late 2007, 8 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1UDW , PDB link 1UEI , PDB link 1UEJ , PDB link 1UFQ , PDB link 1UJ2 , PDB link 1XRJ , PDB link 2JEO , and PDB link 2UVQ . References reflist 1 cite journal author Orengo A date 1969 title Regulation of enzymic activity by metabolites. I. Uridine cytidine kinase of Novikoff ascites rat tumor journal J. Biol. Chem. volume 244 pages 2204&ndash 9 pmid 5782006 issue 8 cite journal author Skold O date 1960 title Uridine kinase from Erlich ascites tumor purification and properties journal J. Biol. Chem. volume 235 pages 3273&ndash 3279 enzyme stub Category EC 2.7.1 Category Enzymes of known structure ... more details
enzyme Name uridine nucleosidase EC number 3.2.2.3 CAS number 9025 47 2 IUBMB EC number 3 2 2 3 GO code 0045437 image width caption In enzymology , an uridine nucleosidase EC number 3.2.2.3 is an enzyme that catalysis catalyzes the chemical reaction uridine H sub 2 sub O math rightleftharpoons math D ribose uracil Thus, the two substrate biochemistry substrates of this enzyme are uridine and water H sub 2 sub O , whereas its two product chemistry products are D ribose and uracil . This enzyme belongs to the family of hydrolase s, specifically those glycosylases that hydrolyse N glycosyl compounds. The systematic name of this enzyme class is uridine ribohydrolase . This enzyme is also called uridine hydrolase . This enzyme participates in pyrimidine metabolism . Structural studies As of late 2007, 23 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1EMH , PDB link 1EMJ , PDB link 1EUG , PDB link 1FLZ , PDB link 1OKB , PDB link 1SSP , PDB link 1UDG , PDB link 1UDH , PDB link 1UDI , PDB link 1UGH , PDB link 1UUG , PDB link 1YUO , PDB link 2BOO , PDB link 2C53 , PDB link 2C56 , PDB link 2EUG , PDB link 2J8X , PDB link 2SSP , PDB link 2UUG , PDB link 3EUG , PDB link 4EUG , PDB link 4SKN , and PDB link 5EUG . References reflist 1 cite journal author Carter CE date 1951 title Partial purification of a non phosphorylytic uridine nucleosidase from yeast journal J. Am. Chem. Soc. volume 73 pages 1508&ndash 1510 doi 10.1021 ja01148a028 issue 4 hydrolase stub Category EC 3.2.2 Category Enzymes of known structure ... more details
lide Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine monophosphate , also known ... of phosphoric acid with the nucleoside uridine . UMP consists of the phosphate Functional group ... . Biosynthesis Uridine monophosphate is formed from Orotidine 5 monophosphate orotidylic acid in a decarboxylation ... of uridine monophosphate, choline, and docosahexaenoic acid DHA were found to have significantly ..., July 3, 2008 ref Uridine Monophosphate in Foods In brain research studies such as those mentioned in this article, uridine monophosphate is used as a convenient delivery compound for uridine . Uridine is the active ingredient of the compound. A common misconception is that uridine and its compounds ... or prescription drugs. This is not so. Uridine monophosphate is a major component of RNA . Any food ... information, consult the article on uridine . References reflist See also Nucleoside Nucleotide ... fr Uridine monophosphate gl Urid n monofosfato it Uridina monofosfato nl Uridinemonofosfaat ... more details
enzyme Name uridine phosphorylase EC number 2.4.2.3 CAS number 9030 22 2 IUBMB EC number 2 4 2 3 GO code 0004850 image width caption In enzymology , an uridine phosphorylase EC number 2.4.2.3 is an enzyme that catalysis catalyzes the chemical reaction uridine phosphate math rightleftharpoons math uracil alpha D ribose 1 phosphate Thus, the two substrate biochemistry substrates of this enzyme are uridine and phosphate , whereas its two product chemistry products are uracil and alpha D ribose 1 phosphate . This enzyme belongs to the family of glycosyltransferase s, specifically the pentosyltransferases. The systematic name of this enzyme class is uridine phosphate alpha D ribosyltransferase . Other names in common use include pyrimidine phosphorylase , UrdPase , UPH , and UPase . This enzyme participates in pyrimidine metabolism . Structural studies As of late 2007, 27 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1K3F , PDB link 1LX7 , PDB link 1RXC , PDB link 1RXS , PDB link 1RXU , PDB link 1RXY , PDB link 1RYZ , PDB link 1SJ9 , PDB link 1SQ6 , PDB link 1T0U , PDB link 1TGV , PDB link 1TGY , PDB link 1U1C , PDB link 1U1D , PDB link 1U1E , PDB link 1U1F , PDB link 1U1G , PDB link 1Y1Q , PDB link 1Y1R , PDB link 1Y1S , PDB link 1Y1T , PDB link 1ZL2 , PDB link 2HN9 , PDB link 2HRD , PDB link 2HSW , PDB link 2HWU , and PDB link 2I8A . References reflist 1 cite journal author CANELLAKIS ES date 1957 title Pyrimidine metabolism. II. Enzymatic pathways of uracil anabolism journal J. Biol. Chem. volume 227 pages 329&ndash 38 pmid 13449076 issue 1 cite journal author PAEGE LM, SCHLENK F date 1952 title Bacterial uracil riboside phosphorylase journal Arch. Biochem. Biophys. volume 40 pages 42&ndash 9 pmid 12997187 doi 10.1016 0003 9861 52 90071 4 issue 1 cite journal author Pontis H, Degerstedt G and Reichard P date 1961 title Uridine and deoxyuridine phosphorylases from Ehrlich ascites tumor journal ... more details
isomerase . Glucose 1 phosphate can then be combined with uridine triphosphate UTP to form UDP glucose ...chembox verifiedrevid 464363195 ImageFileL1 Glucose 6 Phosphate.svg ImageFileR1 Beta D glucose 6 phosphate ... O O O OC O C H 1O MeSHName Glucose 6 phosphate Section2 Chembox Properties Formula C sub 6 sub H sub ... Hazards MainHazards FlashPt Autoignition Glucose 6 phosphate also known as Robison ester is glucose ... majority of glucose entering a cell will become phosphorylated in this way. Because of its prominent position in cellular chemistry , glucose 6 phosphate has many possible fates within the cell. It lies ... to these metabolic pathways, glucose 6 phosphate may also be converted to glycogen or starch for storage ... s, and in intracellular starch or glycogen granules for most other organisms. Production of glucose 6 phosphate From glucose Within a cell, glucose 6 phosphate is produced by phosphorylation of glucose ... ATP is consumed in this reaction. Enzymatic Reaction foward enzyme Hexokinase reverse enzyme Glucose 6 phosphatase substrate small D small Glucose product small D small Glucose 6 phosphate reaction ... minor foward product s adenosine diphosphate ADP minor reverse substrate s H sub 2 sub O minor reverse product s PO su p 3 b 4 substrate image D glucose wpmp.png product image Alpha D glucose 6 phosphate ... reason for the immediate phosphorylation of glucose is to prevent diffusion out of the cell. The phosphorylation adds a charged phosphate group so the glucose 6 phosphate cannot easily cross the cell membrane . From glycogen Glucose 6 phosphate is also produced during glycogenolysis from glucose ... . This will cause the G6P to be dehydrogenated by glucose 6 phosphate dehydrogenase . This reversible ... skeletons for synthesis then glucose 6 phosphate is targeted for glycolysis . Glucose 6 phosphate is first ... Phosphoglucose isomerase reverse enzyme Phosphoglucose isomerase substrate small D small Glucose ... product s substrate image Alpha D glucose 6 phosphate wpmp.png product image Beta D fructose 6 ... more details
chembox verifiedrevid 428766450 ImageFile dTDP chemical structure.png ImageSize 197 IUPACName 2R,3S,5R 3 hydroxy br 5 5 methyl 2,4 dioxopyrimidin br 1 yl oxolan 2 yl methyl phosphono hydrogen phosphate OtherNames Section1 Chembox Identifiers CASNo 1861 44 5 PubChem 164628 SMILES CC1 CN C O NC1 O C H 2C C H C H O2 COP O O OP O O O O MeSHName Section2 Chembox Properties Formula C sub 10 sub H sub 16 sub N sub 2 sub O sub 12 sub P sub 2 sub MolarMass 402.19 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Thymidine diphosphate , abbreviated dTDP , is a nucleoside diphosphate . It is an ester of pyrophosphoric acid with the nucleoside thymidine . dTDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase thymine . Unlike the other deoxyribonucleotide s, thymidine diphosphate does not contain the deoxy prefix in its name. ref cite book title The ACS style guide effective communication of scientific diphosphates information year 2006 publisher American Chemical Society location Washington, D.C. isbn 9780841239999 edition 3rd editor Coghill, Anne M. Garson, Lorrin R. page 244 ref clear See also Nucleoside Nucleotide DNA RNA Oligonucleotide Thymidine diphosphate glucose dTDP glucose References reflist External links Nucleobases, nucleosides, and nucleotides Category Nucleotides biochem stub ca Difosfat de timidina fa nl Thymidinedifosfaat ja sr Timidin difosfat zh ... more details
Bauer S date 1975 title Uridinediphosphate 2 deoxyglucose. Chemical synthesis, enzymic oxidation and epimerization ...enzyme Name UDP glucose 6 dehydrogenase EC number 1.1.1.22 CAS number 9028 26 6 IUBMB EC number 1 1 1 22 GO code 0003979 image width caption In enzymology , an UDP glucose 6 dehydrogenase EC number 1.1.1.22 is an enzyme that catalysis catalyzes the chemical reaction UDP glucose 2 NAD sup sup H sub 2 sub O math rightleftharpoons math UDP glucuronate 2 NADH 2 H sup sup The 3 substrate biochemistry substrates of this enzyme are UDP glucose , nicotinamide adenine dinucleotide NAD sup sup , and water H sub 2 sub O , whereas its 3 product chemistry products are UDP glucuronate , nicotinamide adenine dinucleotide NADH , and hydrogen ion H sup sup . This enzyme belongs to the family of oxidoreductase s, specifically those acting on the CH OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is UDP glucose NAD 6 oxidoreductase . Other names in common use include UDP glucose dehydrogenase , uridine diphosphoglucose dehydrogenase , UDPG dehydrogenase , UDPG NAD oxidoreductase , UDP alpha D glucose NAD oxidoreductase , UDP glucose NAD oxidoreductase , uridinediphosphateglucose dehydrogenase , UDP D glucose dehydrogenase , and uridinediphosphate D glucose dehydrogenase . This enzyme participates in 4 metabolism metabolic pathways pentose and glucuronate interconversions , ascorbate and aldarate metabolism , starch and sucrose metabolism , and nucleotide sugars metabolism . Structural studies As of late 2007, 5 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1DLI , PDB link ... title Some properties of uridine diphosphoglucose dehydrogenase journal Arch. Biochem. Biophys. volume ... STROMINGER JL, MAPSON LW date 1957 title Uridine diphosphoglucose dehydrogenase of pea seedlings journal ... AXELROD J, KALCKAR HM, MAXWELL ES, STROMINGER JL date 1957 title Enzymatic formation of uridine diphosphoglucuronic ... more details
unreferenced date June 2010 chembox verifiedrevid 443837963 ImageFile Glucose 1 phosphate.svg ImageSize 150px ImageCaption Anionic form of small D small glucose 1 phosphate ImageFile2 Cori ester.gif ImageSize2 150px ImageCaption2 Neutral form of small D small glucose 1 phosphate IUPACName Glucose 1 phosphate OtherNames Cori ester Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 388311 InChI 1 C6H13O9P c7 1 2 3 8 4 9 5 10 6 14 2 15 16 11,12 13 h2 10H,1H2, H2,11,12,13 t2 ,3 ,4 ,5 ,6? m1 s1 InChIKey HXXFSFRBOHSIMQ GASJEMHNBR StdInChI Ref stdinchicite correct chemspider StdInChI 1S C6H13O9P c7 1 2 3 8 4 9 5 10 6 14 2 15 16 11,12 13 h2 10H,1H2, H2,11,12,13 ... EBI ChEBI 16077 SMILES O P O OC1O C H C H O C H O C H 1O CO O MeSHName glucose 1 phosphate Section2 ... Solubility MainHazards FlashPt Autoignition Glucose 1 phosphate also called cori ester is a glucose ... of glucose 1 phosphate Catabolic In glycogenolysis , it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure. To be utilized in cellular catabolism it must first be converted to glucose 6 phosphate by the enzyme phosphoglucomutase . One reason that cells form glucose 1 phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism. Anabolic In glycogenesis , free glucose 1 phosphate can also react with Uridine triphosphate UTP to form UDP glucose , by using the enzyme UDP glucose pyrophosphorylase . It can then return to the greater glycogen structure via glycogen synthase . Glucose 1 phosphate Glucose 1 phosphate is found in some microbes. It is produced by inverting glucan ... phosphorylase trehalose phosphorylase and is then converted into glucose 6 phosphate by beta phosphoglucomutase ... metabolic intermediates de Glucose 1 phosphat es Glucosa 1 fosfato fa gl Glicosa ... more details
BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Adenosine diphosphate , abbreviated ADP , is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside ... of ADP to ATP. ref name emc.maricopa.edu Animals use the energy released in the breakdown of glucose ... et Adenosiindifosfaat el ADP es Adenos n difosfato fa fr Ad nosine diphosphate ... difosfato ru simple Adenosine diphosphate sr sh Adenozin difosfat ... diphosphate vi Adenosine diphosphate zh ... more details
Unreferenced date October 2006 Chembox verifiedrevid 447288252 ImageFile 2 Desoxycytidindiphosphat.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo 800 73 7 PubChem 3972 SMILES Nc1ccn C2CC O C COP O O OP O O O O2 c O n1 MeSHName deoxycytidine diphosphate Section2 Chembox Properties Formula C sub 9 sub H sub 15 sub N sub 3 sub O sub 10 sub P sub 2 sub MolarMass 387.177 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxycytidine diphosphate is a nucleoside diphosphate . It is related to the common nucleic acid CTP, or cytidine triphosphate , with the OH hydroxyl group on the 2 carbon on the nucleotide s pentose removed hence the deoxy part of the name , and with one fewer phosphoryl group than CTP . Deoxyguanosine diphosphate would be abbreviated dCDP. See also DNA Cofactor biochemistry Cofactor Cytosine Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxycytidine Diphosphate Category Nucleotides Biochem stub ca Difosfat de desoxicitidina fa gl Desoxicitidina difosfato nl Deoxycytidinedifosfaat sr Dezoksicitidin difosfat zh ... more details
Unreferenced date December 2009 Chembox verifiedrevid 447288204 ImageFile DGDP chemical structure.png ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo PubChem 644 SMILES C1C C OC1N2C NC3 C2NC NC3 O N COP O O OP O O O O Section2 Chembox Properties Formula C sub 10 sub H sub 15 sub N sub 5 sub O sub 10 sub P sub 2 sub MolarMass 427.201122 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxyguanosine diphosphate is a nucleoside diphosphate . It is related to the common nucleic acid GTP, or guanosine triphosphate , with the OH hydroxyl group on the 2 carbon on the nucleotide s pentose removed hence the deoxy part of the name , and with one fewer phosphoryl group than GTP. Deoxyguanosine diphosphate is abbreviated dGDP. See also Nucleic acid DNA metabolism Cofactor biochemistry Cofactor Guanosine Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxyguanosine Diphosphate Category Nucleotides ca Difosfat de desoxiguanosina fa gl Desoxiguanosina difosfato nl Deoxyguanosinedifosfaat sr Dezoksiguanozin difosfat zh ... more details
chembox verifiedrevid 447288226 ImageFile DADP chemical structure.png ImageSize IUPACName nowiki 5 6 aminopurin 9 yl 3 hydroxyoxolan 2 yl methyl phosphono hydrogen nowiki OtherNames dADP Reference ref http pubchem.ncbi.nlm.nih.gov summary summary.cgi?cid 620 dADP Compound Summary , PubChem . ref Section1 Chembox Identifiers CASNo 2793 06 8 PubChem 620 MeSHName Deoxyadenosine diphosphate SMILES C1C C OC1N2C NC3 C2N CN C3N COP O O OP O O O O Section2 Chembox Properties Formula C sub 10 sub H sub 15 sub N sub 5 sub O sub 9 sub P sub 2 sub MolarMass 411.201722 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxyadenosine diphosphate is a nucleoside diphosphate . It is related to the common nucleic acid ATP, or adenosine triphosphate , with the OH hydroxyl group on the 2 carbon on the nucleotide s pentose removed hence the deoxy part of the name , and with one fewer phosphoryl group than ATP. Deoxyadenosine diphosphate is abbreviated dADP. See also Cofactor biochemistry Cofactor Guanosine Cyclic adenosine monophosphate References reflist Nucleobases, nucleosides, and nucleotides Category Nucleotides ca Difosfat de desoxiadenosina fa gl Desoxiadenosina difosfato nl Deoxyadenosinedifosfaat sr Dezoksiadenozin difosfat zh ... more details
Unreferenced stub auto yes date December 2009 Orphan date December 2009 The glucose cycle also known as the hepatic futile cycle occurs primarily in the liver and is the dynamic equilibrium between glucose and glucose 6 phosphate . This is important for maintaining a constant concentration of glucose in the blood stream . Function The glucose cycle is required for one of the liver functions the homeostasis of glucose in the blood stream. When blood glucose levels are in excess, glucose can be stored in the liver as glycogen . When glucose levels in the blood stream are low the glycogen can be catabolism catabolised and glucose may re enter the blood stream. The catabolic process occurs at the nonreducing end of glycogen. A phosphate group breaks the bond between C 1 of a glucose ring and the O that connects it to the next phosphorolysis . One glucose unit is thus split off. Glycogen with n glucose units is converted into G 1 P a PO sub 4 sub group now attaches to C1 where O used to and glycogen with n 1 glucose units by enzyme glycogen phosphorylase. G 1 P is then converted into G 6 P by enzyme phosphoglucomutase. A water molecule hydrolyses G 6 P to glucose, the enzyme is glucose 6 phosphatase. Cell specificity When glucose enters a cell it is rapidly changed to glucose 6 phosphate, by hexokinase or glucokinase . The glucose cycle can occur in liver cells due to a liver specific enzyme glucose 6 phosphatase , which catalyse the dephosphorylation of glucose 6 phosphate back to glucose. Glucose 6 phosphate is the product of glycogenolysis or gluconeogenesis , where the goal is to increase free glucose in the blood due body being in catabolic state. Other cells such as muscle and brain cells do not contain glucose 6 phosphatase. As a result, any glucose 6 phosphate produced .... Regulation of glucose cycle Flux through the glucose cycle is regulated by several hormones including insulin and glucagon as well as allosteric regulation of both hexokinase and glucose ... more details
chembox verifiedrevid 443555075 ImageFile Cytidindiphosphat protoniert.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 5902 InChI 1 C9H15N3O11P2 c10 5 1 2 12 9 15 11 5 8 7 14 6 13 4 22 8 3 21 25 19,20 23 24 16,17 18 h1 2,4,6 8,13 14H,3H2, H,19,20 H2,10,11,15 H2,16,17,18 t4 ,6 ,7 ,8 m1 s1 InChIKey ZWIADYZPOWUWEW XVFCMESIBF ChEMBL Ref ebicite correct EBI ChEMBL 425252 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H15N3O11P2 c10 5 1 2 12 9 15 11 5 8 7 14 6 13 4 22 8 3 21 25 19,20 23 24 16,17 18 h1 2,4,6 8,13 14H,3H2, H,19,20 H2,10,11,15 H2,16,17,18 t4 ,6 ,7 ,8 m1 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey ZWIADYZPOWUWEW XVFCMESISA N CASNo 63 38 7 CASNo Ref cascite correct CAS CASOther br 34393 59 4 disodium salt NOT CAS verified PubChem 290 ChEBI Ref ebicite correct EBI ChEBI 17239 SMILES O P O O OP O O OC C H 2O C H N 1C O N C N C C 1 C H O C H 2O Section2 Chembox Properties Formula C sub 9 sub H sub 15 sub N sub 3 sub O sub 11 sub P sub 2 sub MolarMass 403.176422 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Cytidine diphosphate , abbreviated CDP , is a nucleoside diphosphate . It is an ester of pyrophosphoric acid with the nucleoside cytidine . CDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase cytosine . See also Nucleoside Nucleotide DNA RNA Oligonucleotide External links Nucleobases, nucleosides, and nucleotides Category Nucleotides Category Pyrimidones biochem stub ca Difosfat de citidina da Cytidindifosfat de Cytidindiphosphat fa fr Cytidine diphosphate gl Citid n difosfato it Citosindifosfato nl Cytidinedifosfaat ja sr Citidin difosfat zh ... more details
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