Unreferenced date December 2009 Chembox verifiedrevid 370256222 ImageFile UroporphyrinogenIII skeletal.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo 1976 85 8 PubChem 1179 SMILES MeSHName UroporphyrinogenIII Section2 Chembox Properties Formula C sub 40 sub H sub 44 sub N sub 4 sub O sub 16 sub MolarMass 836.795 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition UroporphyrinogenIII is an metabolic intermediate in the biosynthesis of protoporphyrin . It is created by the enzyme uroporphyrinogenIII synthase , and is converted into coproporphyrinogen III by the enzyme uroporphyrinogenIII decarboxylase . See also Uroporphyrinogen Image Heme synthesis.png center framed Heme synthesis&mdash note that some reactions occur in the cytoplasm and some in the mitochondrion yellow Tetrapyrroles Heme metabolism intermediates DEFAULTSORT UroporphyrinogenIii Category Tetrapyrroles it Uroporfirinogeno III hu Uroporfirinog n III ja III ... more details
enzyme Name UroporphyrinogenIII synthase EC number 4.2.1.75 CAS number 37340 55 9 IUBMB EC number 4 2 1 75 GO code 0004852 image width caption protein Name UroporphyrinogenIII synthase caption image width HGNCid 12592 Symbol UROS AltSymbols EntrezGene 7390 OMIM 606938 RefSeq NM 000375 UniProt P10746 PDB ECnumber 4.2.1.75 Chromosome 10 Arm q Band 25.2 26.3 LocusSupplementaryData Infobox protein family Symbol HEM4 Name UroporphyrinogenIII synthase HemD image PDB 1wd7 EBI.jpg width caption crystal structure of uroporphyrinogeniii synthase from an extremely thermophilic bacterium thermus thermophilus hb8 wild type, native, form 2 crystal Pfam PF02602 Pfam clan InterPro IPR003754 SMART PROSITE MEROPS SCOP 1jr2 TCDB OPM family OPM protein CAZy CDD UroporphyrinogenIII synthase EC number 4.2.1.75 is an enzyme involved in the metabolism of the cyclic tetrapyrrole compound porphyrin . It is involved in the conversion of hydroxymethyl bilane into uroporphyrinogenIII . This enzyme catalysis catalyses the inversion of the final pyrrole unit ring D of the linear tetrapyrrole molecule, linking it to the first pyrrole unit ring A , thereby generating a large macrocyclic structure, uroporphyrinogenIII. ref name pmid11215515 cite journal author Raux E, Schubert HL, Warren MJ title Biosynthesis of cobalamin vitamin B12 a bacterial conundrum journal Cell. Mol. Life Sci. volume 57 issue 13 14 pages 1880 93 year 2000 month December pmid 11215515 doi 10.1007 PL00000670 url ref The enzyme protein ... title Crystal structure of human uroporphyrinogenIII synthase journal EMBO J. volume 20 issue 21 pages ... of metabolism that results from the markedly deficient activity of uroporphyrinogenIII synthase ... year 2007 pmid 17270473 doi 10.1016 j.bcmd.2006.12.001 url ref External links MeshName UroporphyrinogenIII synthase References reflist Porphyrin biosynthesis enzymes Carbon oxygen lyases lyase stub InterPro content IPR003754 Category EC 4.2.1 de UroporphyrinogenIII Synthase ja III ... more details
UROD uroporphyrinogen decarboxylase url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 7389 accessdate ref UroporphyrinogenIII decarboxylase UroD is a homodimeric ... of carboxyl groups from the four acetate side chains of uroporphyrinogenIII to yield coproporphyrinogen III . Clinical significance Mutations and deficiency in this enzyme are known to cause familial ... performed by uroporphyrinogenIII decarboxylase. J Phys Chem B 2005 109 18195 200. DOI ...PBB geneid 7389 Uroporphyrinogen decarboxylase , also known as UROD , is an enzyme that in humans is encoded by the UROD gene . ref name entrez cite web title Entrez Gene UROD uroporphyrinogen decarboxylase ... for catalyzing the conversion of uroporphyrinogen to coproporphyrinogens coproporphyrinogen ... name pmid18988736 cite journal author Lewis CA, Wolfenden R title Uroporphyrinogen decarboxylation ... pmc 2582308 ref Image UroD mechanism.svg thumb left 800px Proposed reaction mechanism of uroporphyrinogenIII decarboxyklase References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Elder GH, Lee GB, Tovey JA title Decreased activity of hepatic uroporphyrinogen ... uroporphyrinogen decarboxylase locus in two patients with hepatoerythropoietic porphyria. journal ... al. title Uroporphyrinogen decarboxylase a splice site mutation causes the deletion of exon 6 in multiple ..., Harrison LM, et al. title A point mutation in the coding region of uroporphyrinogen decarboxylase ... and nucleotide sequence of a complete human uroporphyrinogen decarboxylase cDNA. journal J. Biol. Chem ... MG, Raich N, et al. title Assignment of human uroporphyrinogen decarboxylase URO D to the p34 band ... for human uroporphyrinogen decarboxylase. journal Nucleic Acids Res. volume 15 issue 18 pages 7343 ... B, Beaumont C, et al. title Uroporphyrinogen decarboxylase structural mutant Gly281 Glu in a case ... G281E of the human uroporphyrinogen decarboxylase gene causes both hepatoerythropoietic porphyria ... more details
Uroporphyrinogens are tetrapyrroles with four propionic acid groups P groups and four acetic acid groups A groups . There are four forms, which vary based upon the arrangements of the P and A groups in clockwise order In the I variety i.e. uroporphyrinogen I , the order repeats four times AP AP AP AP. In the III variety i.e. uroporphyrinogen III , the fourth is reversed AP AP AP PA. This is the most common form. In the synthesis of porphyrin , it is created from hydroxymethyl bilane by the enzyme uroporphyrinogen III synthase , and it is converted into coproporphyrinogen III by the enzyme uroporphyrinogen III decarboxylase . The II and IV varieties can be created synthetically, but do not appear in nature. External links MeshName Uroporphyrinogens Tetrapyrroles Category Biomolecules biochem stub ... more details
chembox verifiedrevid 402052189 ImageFile Uroporphyrinogen I.png ImageSize 200px IUPACName OtherNames Section1 Chembox Identifiers CASNo 1867 62 5 PubChem 440775 SMILES Section2 Chembox Properties Formula C sub 40 sub H sub 44 sub N sub 4 sub O sub 16 sub MolarMass 836.795 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uroporphyrinogen I is a tetrapyrrole which accumulates in acute intermittent porphyria . Tetrapyrroles Biochem stub Category Tetrapyrroles it Uroporfirinogeno I ja I ... more details
for ill ill disambiguation For any media or product titled III meaning the number 3 disambiguation wiktionary IIIIIIiii may refer to III Records , a Japanese record label Hank Williams III or III born 1972 , American country singer Information International, Inc. , a computer technology company Innovative Interfaces, Inc. , a library software company Insurance Information Institute , a US industry organization Intelligence and Information Institute , a fictional USA government organization in the comic version of Transformers Interactive Investor International Interstate Identification Index , an index of criminal records maintained by the FBI III, the Inti Creates sound team III, Group 3 element in the periodic table III Level 3 , the highest rating used in Hong Kong motion picture rating system Hong Kong film distribution and classification Fairey III , a family of British reconnaissance aircraft See also 3 disambiguation disambig Category Initialisms de III eo III fr III it III nl III ja III no III ru III ... more details
Unreferenced stub auto yes date December 2009 Chembox verifiedrevid 357151114 ImageFile Coproporphyrinogen III.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo 2624 63 7 PubChem 321 SMILES MeSHName Coproporphyrinogen III Section2 Chembox Properties Formula C sub 36 sub H sub 44 sub N sub 4 sub O sub 8 sub MolarMass 660.757 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition In the metabolism of porphyrin , the enzyme uroporphyrinogen III decarboxylase generates coproporphyrinogen III from uroporphyrinogen III , and coproporphyrinogen III oxidase converts it into protoporphyrinogen IX . Image Heme synthesis.png center framed Heme synthesis&mdash note that some reactions occur in the cytoplasm and some in the mitochondrion yellow Tetrapyrroles Heme metabolism intermediates DEFAULTSORT Coproporphyrinogen Iii Category Tetrapyrroles Biochem stub it Coproporfirinogeno III ja III ... more details
Infobox album See Wikipedia WikiProject Albums Name I III II IIIIIIIII Type EP Longtype series Artist Poison the Well band Poison the Well Cover PoisonthewellEPCOLLECTION.jpg Caption Cover art for the CD release compiling all three EPs. Though similar, it s not the same as the art found on the individual EPs. Released November 2008 May 2009 Recorded 2007 during the Versions sessions Genre Hardcore punk br Post hardcore br Experimental rock Length 18 39 Label Ferret Music Producer Eskil L vstr m, Pelle Henricsson Reviews Last album Versions Poison the Well album Versions br 2007 This album I III II IIIIIIIII br 2008 2009 Next album The Tropic Rot br 2009 Misc Extra album cover Upper caption Individual covers Type EP Cover Poisonthewell imagecompilation.jpg Lower caption All three EPs combined together to create a larger image. The band s logo spreads across all three covers. I III II IIIIIIIII pronounced as One of Three, Two of Three, Three of Three is a limited edition set of three 7 vinyl records by post hardcore band Poison the Well band Poison the Well . The collection features ... album, later to be known as The Tropic Rot . All songs from I III II IIIIIIIII were also made ... by Poison the Well. The limited edition CD features all six songs in this order. I III New Fast 2 11 Purple Sabbath 4 52 II III Shuffle 3 20 Bowie 4 40 IIIIII A No.1 2 35 Run Desire Gone Clean 1 02 Release history class wikitable Release date Album Format Quantity Catalog November 11, 2008 I III ... http www.ferretstyle.com artist.php?id 135 Poison the Well, Featured Release I III Ferret Music Website. Retrieved on March 24, 2009. ref January 20, 2009 II III 7 vinyl, digital download Limited quantity ... II III Ferret Music Website. Retrieved on March 24, 2009. ref Record Store Day April 18, 2009 I III II IIIIIIIII Compact Disc 2,000 copies ref name 2000copies Ferret F124 May 19, 2009 IIIIII ... Official Website Poison the Well DEFAULTSORT I Iii Ii IiiIiiIii Category Poison the Well albums ... more details
Boleslaus III may refer to Boleslaus III of Bohemia Boleslaus III the Wrymouth hndis Long comment to avoid being listed on short pages lv Bo eslavs III sv Boleslav III ... more details
Peter III may refer to Pope Peter III of Alexandria 477 Peter III of Bulgaria ruled in 1072 Peter III of Aragon 1239 1285 Peter III of Arborea died 1347 Pedro III of Kongo ruler in 1669 Peter III of Portugal 1717 1786 Peter III of Russia 1728 1762 See also Pedro III disambiguation hndis Peter III an Pietro III br Pedro III ca Pere III cs Petr III. es Pedro III fr Pierre III gl Pedro III it Pietro III lt Petras III reik m s hu III. P ter egy rtelm s t lap nl Peter III ja 3 no Peter III pl Piotr III pt Pedro III fi Pietari III sv Peter III zh ... more details
Sancho III may refer to King Sancho III of Navarre c. 985 1035 King Sancho III of Castile 1134 1158 hndis Sancho 03 de Sancho III. es Sancho III eu Antso III.a argipena fr Sanche III gl Sancho III ko 3 la Sanctius III hu III. Sancho egy rtelm s t lap ja 3 pl Sancho III pt Sancho III ru III ... more details
Alexander III may refer to Alexander III of Macedon 356 BC 323 BC , also known as Alexander the Great Alexander emperor , Byzantine Emperor 912 913 Pope Alexander III , pope from 1159 to 1181 Alexander III of Scotland 1241 1286 , king of Scotland Alexander III of Imereti 1609 1660 , king of Imereti Alexander III of Russia 1845 1894 , emperor of Russia Pont Alexandre III , an arch bridge that spans the Seine Russian battleship Imperator Aleksander III Russian warship See also King Alexander disambiguation disambiguation hn DEFAULTSORT Alexander 03 bg III br Aleksandr III ca Alexandre III cs Alexandr III. de Alexander III. et Aleksander III t psustus es Alejandro III fa fr Alexandre III gl Alexandre III it Alessandro III he lv Aleksandrs III hu III. S ndor egy rtelm s t lap mk III nl Alexander III no Aleksander III pl Aleksander III pt Alexandre III ro Alexandru al III lea ru III sk Alexander III. fi Aleksanteri III sv Alexander III tr III. Aleksander uk III vi Alexander III zh ... more details
William III may refer to William III of Aquitaine 915 963 William III of Toulouse died 1037 William III of Provence died after 1037 William III of Montferrat 970 1042 William III of Angoul me 1084 1118 William III of Ponthieu c. 1095 1172 William III of Sicily 1190 1198 William III of Dampierre 1224 1251 William III of Cagliari ruled 1256 1258 Sir William Douglas the Hardy died c. 1298 William I, Count of Hainaut or William III of Holland 1286 1337 Uilleam III, Earl of Ross died 1370 William I, Duke of Bavaria or William III of Hainaut 1330 1389 William III, Duke of Bavaria 1375 1435 William III, Duke of Luxembourg 1425 1482 William III of England or William III of Orange or William II of Scotland 1650 1702 William III of the Netherlands 1817 1890 hndis William III ca Guillem III cs Vil m III. cy Wiliam III de Wilhelm III. et Guglielmo III es Guillermo III fr Guillaume III it Guglielmo III nl Willem III nds nl Willem III pl Wilhelm III ru III fi Vilhelm III sv Vilhelm III zh ... more details
Albert III may refer to Albert III of Austria 1349 1395 Albert III, Duke of Bavaria 1438 1460 Albert III, Margrave of Brandenburg 1414 1486 Albert III, Count of Namur 1048 1102 Albert III, Prince of Anhalt Zerbst d. 1359 Albert III, Duke of Saxe Wittenberg 1375 1380 1422 Albert, Duke of Saxony 1443 1500 , sometimes called Albert III hndis Albert III de Albert III. et Albert III fr Albert III it Alberto III hu III. Albert egy rtelm s t lap nl Albert III pl Albrecht III ru III uk III ... more details
Alfonso III may refer to Alfonso III of Leon 866 914 surnamed the Great Afonso III of Portugal 1210 1279 Alfonso III of Aragon 1285 1291 Alfonso III d Este , Duke of Modena and Reggio 1628 1644 Alfonso III of Kongo 1666 1667 hndis an Alifonso III ca Alfons III es Alfonso III fr Alphonse III gl Afonso III ko 3 ka III hu III. Alfonz egy rtelm s t lap nl Alfons III ja 3 pl Alfons III pt Afonso III fi Alfonso III sv Alfons III zh ... more details
Maximilian III may refer to Maximilian III, Archduke of Austria 1558 1618 Maximilian III Joseph, Elector of Bavaria 1727 1777 hndis Maximilian III br Masimilian III de Maximilian III. et Maximilian III ko 3 lv Maksimili ns III ja 3 ... more details
Constantine III may refer to Constantine III Western Roman Emperor , self proclaimed western Roman Emperor 407 411 Constantine III Byzantine emperor , Byzantine Emperor in 641 Constantine III of Scotland , king of Scotland 995 997 Constantine III of Britain , legendary 6th century King of the Britons Constantine III of Armenia Patriarch Constantine III of Constantinople See also Constantius III hndis bs Konstantin III vor cy Cystennin III fa fr Constantin III it Costantino III he la Constantinus III hu III. Konstantin egy rtelm s t lap nl Constantijn III pl Konstantyn III ru III ... more details
Frederick III may refer to Frederick III of Sicily self styled , also known as King Frederick II of Sicily, 1272 1337 Frederick III of Germany or Frederick the Fair, King of the Romans and previously Duke Frederick I of Austria, 1289 1330 Frederick III the Simple , king of Sicily, 1341 1377 Frederick III, Holy Roman Emperor , 1415 1493 Frederick III, Elector of Saxony , 1463 1525 Frederick III, Elector Palatine , 1515 1576 Frederick III, Duke of Holstein Gottorp , 1597 1659 Frederick III of Denmark , 1609 1670 Frederick III of Brandenburg or Frederick I of Prussia, Elector of Brandenburg, 1657 1713 Frederick III, Duke of Saxe Gotha Altenburg , 1699 1772 Frederick III, German Emperor , 1831 1888 hndis br Frederig III ca Frederic III cs Fridrich III. de Friedrich III. es Federico III fr Fr d ric III fy Freark III ko 3 it Federico III lv Fr drihs III lt Frydrichas III hu III. Frigyes egy rtelm s t lap nl Frederik III ja 3 pl Fryderyk III ru III sk Fridrich III. sl Friderik III. fi Fredrik III sv Fredrik III zh ... more details
Philip III may refer to Philip III of Macedon c. 359 317 BC Philip III of France 1245 1285 Philip III of Navarre 1328 1342 Philip III of Taranto , Principality of Achaea Prince of Achaea 1364 1373 Philip III, Duke of Burgundy the Good 1419 1467 Philip III of Spain and II of Portugal 1578 1621 Philip IV of Spain and III of Portugal 1605 1665 See also Felipe III disambiguation hndis ar ast Felipe III br Fulup III ca Felip III cs Filip III. de Liste der Herrscher namens Philipp Philipp III. es Felipe III eo Filipo regantoj Filipo la 3 a fa fr Philippe III ko 3 hr Filip III. it Filippo III he la Philippus III lt Pilypas III hu III. F l p egy rtelm s t lap nl Filips III ja 3 pl Filip III ru III sk Filip III. fi Filip III sv Filip III vi Philip III vls Filips III zh ... more details
Cotys III or Kotys III can refer to two kings of Thrace Cotys III Odrysian , ruled ca. 270 BC Cotys III Sapaean , ruled 12 19 AD hndis ... more details
Baldwin III may refer to Baldwin III, Count of Flanders 940 962 Baldwin III, Count of Hainaut 1088 1120 Baldwin III of Jerusalem 1130 1162 Baldwin III of Ramla early 1330s c. 1187 or 1186 1188 hndis Baldwin III cs Balduin III. fr Baudouin III ko 3 he lt Balduinas III pl Baldwin III ... more details
Harald III or Harold III may refer to Harald III of Denmark 1041 1080 Harald III of Norway 1015 1066 Harald III, Earl of Orkney floruit fl. 1190s Harald Eiriksson hndis de Harald III. hr Harald III. et Harald III fr Harald III ja 3 pl Harald III zh ... more details
Leopold III can refer to Leopold III, Margrave of Austria 1073 1136 , sixth Margrave of Austria Leopold III, Duke of Austria 1351 1386 , co Archduke of Austria and co Duke of Styria Leopold III, Duke of Anhalt Dessau 1740 1817 , first Duke of Anhalt Dessau Leopold III, Prince of Lippe 1821 1875 Leopold III of Belgium 1901 1983 , fourth King of the Belgians hndis Leopold III cs Leopold III. de Liste der Herrscher namens Leopold Leopold III. et Leopold III es Leopoldo III fr L opold III hr Leopold III. lt Leopoldas III nl Leopold III ja 3 pl Leopold III ru III sk Leopold III. sv Leopold III tr III. Leopold ... more details
Pedro III may refer to Pedro III of Aragon 1239 1285 Pedro III of Kongo fl. 1669 1680 Pedro III of Portugal 1717 1786 See also Peter III disambiguation hndis Pedro 03 ... more details
Charles III may refer to Charles the Fat , Charles III of East Francia, 832 888 Charles the Simple , Charles III of West Francia, 879 929 Charles of Valois , duke Charles III of Anjou 1290 1325 Charles III of Alen on 1337 1375 Charles III of Naples died 1386 Charles III of Navarre , the Noble 1361 1425 Charles III, Duke of Bourbon 1490 1527 Charles III, Duke of Savoy , the Good 1486 1553 Charles III, Duke of Lorraine 1543 1608 Charles VI, Holy Roman Emperor , also Charles III of Hungary and pretender to the throne of Spain as Charles III. 1685 1740 Karl III Philip, Elector Palatine 1661 1742 Charles Edward Stuart 1720 1788 , also known as Bonnie Prince Charlie and the Young Pretender, styled himself Charles III, King of England and Scotland Charles III of Spain 1716 1788 Charles XIV John of Sweden Charles III John of Norway or Charles XIV John of Sweden 1763 1844 Charles III, Duke of Parma 1823 1854 Charles III, Prince of Monaco 1818 1889 Charles I of Austria , also known as Charles III, King of Bohemia, 1887 1922 Possible future regnal title of Charles, Prince of Wales born in 1948 Charles the 3rd is a boss character from the video game Viewtiful Joe hndis Charles III bg III ca Carles III cs Karel III. cy Siarl III et Charles III t psustus es Carlos III fr Charles III gl Carlos III it Carlo III lt Karolis III hu III. K roly egy rtelm s t lap nl Karel III ja 3 nn Karl III pl Karol III ru III sk Karol III. fi Kaarle III sv Karl III vls Karel III zh ... more details
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