16th district may refer to a number of districts.

• United States congressional districts
  • California's 16th congressional district
  • Florida's 16th congressional district
  • Illinois's 16th congressional district
  • Massachusetts's 16th congressional district
  • Michigan's 16th congressional district
  • Missouri's 16th congressional district
  • New York's 16th congressional district
  • Ohio's 16th congressional district
  • Pennsylvania's 16th congressional district
  • Texas's 16th congressional district
  • Virginia's 16th congressional district

• XVIe arrondissement of Paris