AA amyloidosis is a form of amyloidosis associated with serum amyloid A protein (SAA), an acute-phase protein.^[1] It causes reactive systemic amyloidosis, as a "reaction" to inflammation, but also familial Mediterranean fever, which is an inheritable condition.^[2]

Presentation

The common feature to conditions associated with reactive systemic amyloidosis is long-standing cell breakdown due to chronic inflammatory or disease processes.

Associated conditions

It is associated with chronic inflammatory conditions, including: rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, tuberculosis, bronchiectasis, chronic osteomyelitis.

Other conditions include Hodgkin disease, renal cell carcinoma.

It can be associated with nephrotic syndrome.^[3]

References

sv:AA-amyloidos